Polymerase δ and εin colon cancer

Aaron Stevens

Polymerase δ and ε contain both polymerase and exonuclease domains

Polymerase δ and ε are the major replicative polymerases

Pol δ and ε help repair damage

Mutating the exonuclease domain leads to decreased survival rates

Point mutations in Pol δ are found in colon cancer

Mutating the exonuclease domain of Polymerase δ leads to cancer

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