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PHYSIOLOGY OF PREGNANCY BY TIYAS K DEPARTMENT OF CHILD & MATERNITY NURSING, AIRLANGGA UNIVERSITY, 2013

Physiology of Pregnancy

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CONCEPT OF PREGNANCY

PHYSIOLOGY OF PREGNANCYBYTIYAS KDEPARTMENT OF CHILD & MATERNITY NURSING, AIRLANGGA UNIVERSITY, 2013Definition of pregnancyThe period from conception to birth (wordnet.princeton.edu/perl/webwn )

Pregnancy is a state in which a woman carries a fertilized egg inside her body (medical-dictionary.thefreedictionary.com/pregnancy)Conception Fertilization of an ovum by a spermatozoon

Cell division

Chromosome exchange

Normal PregnancySpans 40 weeks without any complication in either mother & fetus

Trimesters:First: weeks 1 through 13 Second: weeks 14 through 26 Third: weeks 27 through 40

Fetal Growth

Signs and symptomsPresumptive indicators Missed menstrual period Home pregnancy test positive Amenorrhea, nausea, vomiting, breast tenderness, urinary frequency, fatigue (morning sickness) Quickening (perception of fetal movement)

Probable indicatorsUterine enlargement Braxton Hicks contractions Uterine souffle Ballotement Positive pregnancy test

Positive indicatorsPresence of fetal heartbeat distinct from mothers Fetal movement felt by someone other than mother Visualization (e.g., ultrasound examination)

Diagnosis of Pregnancy USGDoppler ExaminationEstimated date of birth (EDB)Ngeles rule Determine first day of LMP(Last Menstrual Period), subtract 3 months, add 7 days plus 1 year Alternatively, add 7 days to LMP and count forward 9 months

Adaptation of PregnancyPsychosocial adaptation:Maternal adaptation Accepting pregnancy Identifying with mother role Reordering personal relationships Establishing relationship with fetus Emotional attachment Preparing for childbirth

Adaptation of PregnancyPsychosocial adaptation:Paternal adaptation Accepting pregnancy Identifying with father role Reordering personal relationships Establishing relationship with fetus Emotional attachment Preparing for childbirth Sibling adaptation Grandparent adaptation

Physical ChangesHormonesEndocrine systemReproduction systemHematology systemRespiratory systemUrinary systemGastrointestinal systemBone and integument system

Pregnancy HormonesHuman Chorionic Gonadotropin(hCG)glicoprotein lutein hormone like structure Produce by trophoblast. Rising level to 9th WOP. To maintain corpus luteum wich produce oestrogen & proqesteron before placenta is available Change in smell & taste nauseaDecreasing immunosupresan reduce mother rejection to placenta15Pregnancy HormonesHuman Placental Lactogen(hPL)Polipeptide produce by syntiotrophoblastProduce time 510days after implantation Reduce mother responds to insulin sugar intake on mother > extra cell matrix water water retention edemaPregnancy HormonesProgesteroneProduce by syntiotrophoblastLowering excitability of white muscle (myometrium, ureter, usus)Increasing sensitivity of chemoreceptor on CO2Increasing temperature 0,51,0Cinduce varicose & hemorrhoids cause by dilatation of vein on lower extremity & rectal

Hormone level during pregnancy

Endocrine system>> sekresi ACTH>> Beta endorfin on 3rd trimester >> oxytocin sekretion > corticosteroid @cortisol higher level in morning , induce striae >> T3 & T4 intestine calcium absorbtion >>, excretion by the renal > contraction frequency (5% per week) especially nocturnal

CERVIXCervix thickness & soften start at 2nd trimestercervix Mucus sticky to avoid infection

VAGINA>> blood flow vena enlargement >> mucus + normal bacteria vagina >acid

UTERUS

Hematology systemHemodilutionIncreased blood volume 3050% from week 734 Hemoglobin, immunoglobulin, platelet & protein >hyperventilationSnoring especially women with preeclampsia (Izci etal,2005)

Urinary systemIncreased GFR 4050% on 1st trimesterActivity of Reninangiotensinaldosterone system increaseelektrolitGlycosuriaUrinate frequencies >>

Gastrointestinal systemSlow gastric emptyingNausea, vomiting constipation

Mother Weight DistributionFetal weight : 28%Plasenta : 5,7%amnion : 4,1%uterus : 8%breast : 6,5%Blood volume : 13,1%Body fat : 33,6%(Neil, 1995)Increase Body WeightBMI PRENATALNormal Increase of body weight (Kg)Underweight ( Melanocyte stimulating hormone hyper pigmented skin

Striae

Linea nigra

Care ManagementPurpose of prenatal care is to identify existing risk factors and other deviations from normal Emphasis on preventive care and optimal self-care

AssessmentInitial visit: interview Reason for seeking care Current pregnancy Obstetric and gynecologic history Medical history Nutritional history History of drug use Family history Social and experiential history History of physical abuse Review of systems Physical examination Laboratory tests

Follow-up visits Interview Physical examination Fetal assessment Fundal height Gestational age Health status Laboratory tests Multiple-marker or triple-screen blood test Other blood tests (RPR/VDRL, CBC, anti-Rh) Other tests Ultrasonography Amniocentesis

Obstetric History TerminologyG (gravida): the current pregnancyT (term births): the number of pregnancies ending >37 weeks gestation, at termP (preterm births): the number of preterm pregnancies ending >20 weeks or viability but before completion of 37 weeksA (abortions): the number of pregnancies ending before 20 weeks or viabilityL (living children): number of children currently living

36Physical ExaminationPelvic examinationExamination of external and internal genitaliaBimanual examinationPelvic shape: gynecoid, android, anthropoid, platypelloidPelvic measurements: diagonal conjugate, true (obstetric) conjugate, and ischial tuberosity

37Abdomen Leopolds maneuvers

Fundal height (FH) and age of gestation by Mc Donalds

Months of gestation = FH ( cm ) X 2/7weeks of gestation = FH ( cm ) X 8/7

Estimated Fetal Weight (EFW) based onJohnson Tausack formula

EBW = [FH(cm) N ] X 155

N = 13 if fetal head have not pass the pelvic inlet yetN = 12 if fetal head is above the spina iskhiadika.N = 11 if fetal head is below the spina iskhiadika.AuscultationNormal Fetal Heart Beat(FHB) = 120160 times/ min Follow-up VisitsVisit schedule: Every 4 weeks up to 28 weeksEvery 2 weeks from 29 to 36 weeksEvery week from 37 weeks to birth

421st Trimester DiscomfortsUrinary frequency or incontinence (see Teaching Guidelines 12-1)FatigueNausea and vomitingBreast tendernessConstipationNasal stuffiness, bleeding gums, epistaxisCravingsLeukorrhea432nd Trimester DiscomfortsBackacheVaricosities of the vulva and legsHemorrhoidsFlatulence with bloating443rd Trimester DiscomfortsReturn of 1st trimester discomfortsShortness of breath and dyspneaHeartburn and indigestionDependent edemaBraxton Hicks contractions

45Intervention Education on:Nutrition Personal hygiene Prevention of urinary tract infections Kegel exercises Preparation for breastfeeding newborn Dental health Physical activity Posture and body mechanics Rest and relaxation Employment and travel Clothing

Medications Immunizations Alcohol, cigarettes, and other substances Normal discomforts Recognizing potential complications Printed list of signs and symptoms Emergency telephone numbers Recognizing preterm labor After the 20th week Before 37th week of pregnancy Uterine contractions, if untreated, cause cervix to open earlier, with resulting preterm birth

Sexual counseling Permission Countering misinformation Suggesting alternative behaviors Psychosocial support Cultural influences Emotional response Clothing Physical activity and rest Sexual activity Diet

Childbirth and Perinatal EducationBirth setting choices Labor, delivery, recovery, postpartum (birthing) rooms Birth centers Home birth Factors increasing the safety of birth at home Pain management

Key Points Maternal physical and familial adaptations to pregnancy generate needs that nurse can anticipate and meet Nurse must be alert to hazards such as supine hypotension, warning signs and symptoms, and signs of family maladaptation Each pregnant woman needs to know how to recognize and report preterm labor Cultural prescriptions and proscriptions influence responses to pregnancy and health care Childbirth education helps parents make transition from role of expectant parents to role and responsibilities of parents