Phys Ther. 2011 August; 91(8): 11981207.
Published online 2011 May 26. doi: 10.2522/ptj.20100372PMCID:
PMC3145896
Associations Between Physical Performance and Executive Function
in Older Adults With Mild Cognitive Impairment: Gait Speed and the
Timed Up & Go Test
Ellen L. McGough, Valerie E. Kelly, Rebecca G. Logsdon, Susan M.
McCurry, Barbara B. Cochrane, Joyce M. Engel, Linda TeriAuthor
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article has been cited by other articles in PMC.
Go to:Abstract
Background
Older adults with amnestic mild cognitive impairment (aMCI) are
at higher risk for developing Alzheimer disease. Physical
performance decline on gait and mobility tasks in conjunction with
executive dysfunction has implications for accelerated functional
decline, disability, and institutionalization in sedentary older
adults with aMCI.
Objectives
The purpose of this study was to examine whether performance on
2 tests commonly used by physical therapists (usual gait speed and
Timed Up & Go Test [TUG]) are associated with performance on 2
neuropsychological tests of executive function (Trail Making Test,
part B [TMT-B], and Stroop-Interference, calculated from the Stroop
Word Color Test) in sedentary older adults with aMCI.
Design
The study was a cross-sectional analysis of 201 sedentary older
adults with memory impairment participating in a longitudinal
intervention study of cognitive function, aging, exercise, and
health promotion.
Methods
Physical performance speed on gait and mobility tasks was
measured via usual gait speed and the TUG (at fast pace). Executive
function was measured with the TMT-B and Stroop-Interference
measures.
Results
Applying multiple linear regression, usual gait speed was
associated with executive function on both the TMT-B (=0.215,
P=.003) and Stroop-Interference (=0.195, P=.01) measures,
indicating that slower usual gait speed was associated with lower
executive function performance. Timed Up & Go Test scores (in
logarithmic transformation) also were associated with executive
function on both the TMT-B (=0.256, P Literature > PubMed
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145896/?report=classic
