1

PharmaceuticalSciencesDepartmentalScholarship2015-2016

Facultyunderlined,*PharmacyStudents,**GraduateStudents/Residents

1.GarstC*,FulmerM,ThewkeD,andBrownS.Optimizedextractionof2-arachidonylglycerolandanandamidefromaortictissueandplasmaforquantificationbyLC-MS/MS.EuropeanJournalofLipidScienceandTechnology,2016;118:814-820.

2.KirkLM*,LuuY*,LewisPO*,andBrownSD.Stabilityofcommercially-availablegrapeandcompoundedcherryoralvancomycinpreparationsstoredinsyringesandcups.InternationalJournalofPharmaceuticalCompounding,20(2);March-April2016,159-163.

3.KyleAR*,CarmicalJ*,ShahD*,PryorJ*,BrownS.UHPLC-MS/MSquantificationofbuprenorphine,norbuprenorphine,methadone,andglucuronideconjugatesinumbilicalcordplasma.BiomedicalChromatography2015:29;1567-1574.

4.BentleyJ*,SnyderF*,BrownS,BrownR,PondB.Sexdifferencesind,l-methylphenidatekinetics.EuropeanReviewforMedicalandPharmacologicalSciences.2015;19(13):2514-2519

5.KirkLM*,Brown,SD.Beyond-usedatedeterminationofbuprenorphinebuccalsolutionusingastability-indicatinghigh-performanceliquidchromatographicassay.JournalofFelineMedicineandSurgery2015Dec;17(12):1035-40,doi:10.1177/1098612X15569329

6.Papich,MG,BrownS,Kirk.L*.Howto(properly)determinethebeyond-usedateandstabilityofacompoundedformulationforpets.JournalofFelineMedicineandSurgery(LettertotheEditor),18(4);364-365,2016.

7.Peters,HT*,Strange,LG*,BrownSD,PondBB.Establishingapharmacokineticprofileofmethylphenidateuseinpregnancy:astudyinmice.Neurotoxicology&Teratology,2016(InPress)

8.CarmicalJ,*BrownSD.TheImpactofPhospholipidsandPhospholipidRemovalonBioanalyticalMethodPerformance.BiomedicalChromatography2016(Inpress).

9.LuuY*,ThigpenJ,BrownSD.StabilityofSildenafilinCombinationwithHeparinandDopamine.AmericanJournalofHealth-SystemsPharmacy,Accepted:March2015,ManuscriptID-2015AJHP0853

10.PetersJ*,KeaslingR*,BrownS,PondB.QuantificationofsyntheticcathinonesinratbrainusingHILIC-ESI-MS/MS.JournalofAnalyticalToxicology,AcceptedMay2016,ManuscriptID–JAT-16-2050.R1

11.MurrellDE**,CaricoRL*,BossaerJB,HarirforooshS,CluckDB.Isavuconazoniumsulfate:atriazoleprodrugforinvasivefungalinfections.InternationalJournalofPharmacyPractice(Accepted)

12.HarirforooshS,StewartDW.Adescriptiveinvestigationoftheimpactofstudentresearchprojectsarisingfromelectiveresearchcourses.BMCResearchNotes.2016;9:48

2

13.MurrellDE**,HarirforooshS.ImprovingtherenalprofileofaHIVdrugcombinationthroughprodrugalteration.JournalofIntegrativeNephrologyandAndrology2016;3:1-2

14.CooperDL**,CarmicalJA*,PanusPC,HarirforooshS.Formulationandinvitroevaluationofniacin-loadednanoparticlestoreduceprostaglandinmediatedvasodilatoryflushing.EuropeanReviewforMedicalandPharmacologicalSciences2015;19:3977-3988

15.PalauVE,ChakrabortyK,WannD,HiltonK,LightnerJ,BrannonM,StoneW,KrishnanK.2016γ-TocotrienolupregulatesceramidebyactivationofthedenovosynthesispathwayandsphingomyelinhydrolysisandmodulatesphingolipidcellulartransportanddistributionviaARV1andCERTinpancreaticcancerMIAPaCa-2cells.FreeRadicalBiologyandMedicine.Acceptedforpublication8-2016;underrevision.

16.TorrenegraRD,Rodriguez,J.Rodriguez,OE,PalauVE,MendezGM2016.Antiproliferativeactivityof3,5,7trihydroxy-6-methoxyflavoneobtainedfromChromolaenaleivensis(Hieron)oncancercelllinesofthebreast,prostate,colon,lungandcervix.Pharmacologyonline1:7-11

17.CrossK,PalauVE,BrannonM,LightnerJ,DycusM,StoneW,KrishnanK.Delta-tocotrienolandsimvastatininducecytotoxicityandsynergyinBRAFmutantSK-MEL-28butnotinwildtypeBRAFSK-MEL-2melanomacancercells.CancerResearch75(15Supplement)July2016

18.RoseA,WannD,LightnerJ,BrannonM,StoneW,PalauVE,KrishnanK.Metforminsuppressessynthesisofprosurvivalsphingolipid,sphingosine-1-phosphate,byinhibitionofsphingosinekinase-1inMCF-7andSK-BR-3breastcancercelllines.CancerResearch75(15Supplement)·July2016

19.WannD,PalauVE,LightnerJ,BrannonM,StoneW,KrishnanK.MetformindecreasescellularceramidesinMCF-7andMDA-MB231breastcancercelllinesbyinhibitionofceramidesyntheticenzymes.CancerResearch75(15Supplement):4639-4639·July2015

20.WhittedCL**,PalauVE,TorrenegraRD,HarirforooshS.2015.Developmentofreversed-phasehighperformanceliquidchromatographymethodsforquantificationandpharmacokineticsoftwoisomericflavonesinrats.ChromatographyB1001:150-155·July2015

21.LeJeuneT*,TsuiHY*,ParsonsLB*,PearsonK*,WyattJE*,WhittedCL**PatelJU*,AdamsCB*,D.Street*,MillerG,RamsauerRE,McPhersonB,TsuiHM*,WheelerJ*,LivesayC*,RodriguezOE,TorrenegraRD,KrishnanK,andPalauVE.2015Mechanismofactionoftwoflavoneisomerstargetingcancercellswithvaryingdifferentiationstatus.PLoSOne10(11).

22.BossaerJB,PanusPC,StewartDW,HagemeierNE.StudentPerformanceinaPharmacotherapyOncologyModulebeforeandafterFlippingtheClassroom.AmJPharmEduc.201680(2)Article31.

23.WallsZF,GongH,WilsonRJ.LiposomalCoencapsulationofDoxorubicinwithListeriolysinOIncreasesPotencyviaSubcellularTargeting.MolPharm.2016Jan25.

PharmacyPracticeDepartmentalScholarship2015-2016

3

1. AdamsCB,StreetDS,CrassM,BossaerJB.LowrateofcetuximabhypersensitivityreactionsinNortheastTennessee:AnAppalachianeffect?JournalofOncologyPharmacyPractice2015http://doi.org/10.1177/1078155215618771

2. AlexanderKM.Children’sAllergyOTCMedicationsandtheUseofProperDosingDevices.StudentPharmacistMagazine(APhA),2015;11(6).

3. AlexanderKM,BurchetteJE,SmithgallS**,CluckD.ObservationsfromthePhaseIIMatch:ImpactonStudentResidencyCandidates.AmJPharmEd,Inpress.

4. BinanayCA,AkwanaloCO,AruasaW,BarasaFA,CoreyGR,CroweS,BloomfieldGS.BuildingSustainableCapacityforCardiovascularCareataPublicHospitalinWesternKenya.JournaloftheAmericanCollegeofCardiology,2015;66(22),2550–2560.http://doi.org/10.1016/j.jacc.2015.09.086

5. BossaerJB,ChakrabortyK.Druginteractionbetweenidelalisibanddiazepamresultinginalteredmentalstatusandrespiratoryfailure.JournalofOncologyPharmacyPractice:OfficialPublicationoftheInternationalSocietyofOncologyPharmacyPractitioners(2016).http://doi.org/10.1177/1078155216653705

6. BossaerJB,GeraciSA,ChakrabortyK.CardiovascularToxicityandManagementofTargetedCancerTherapy.TheAmericanJournaloftheMedicalSciences,2016;351(5),535–543.http://doi.org/10.1016/j.amjms.2016.02.023

7. BossaerJB,PanusP,StewartDW,HagemeierNE,GeorgeJ.StudentPerformanceinaPharmacotherapyOncologyModuleBeforeandAfterFlippingtheClassroom.AmericanJournalofPharmaceuticalEducation,2016;80(2),31.http://doi.org/10.5688/ajpe80231

8. BurchetteJE,CambellD,GeraciS.Preventinghospitalizationsfromacuteexacerbationsofchronicobstructivepulmonarydisease.AmericanJournaloftheMedicalSciences,2016;InPress.

9. ClementsJN,WhitleyHP,D’SouzaJJ,GrossB,HessR,ReeceS,ShealyK.Sodiumglucoseco-transporterinhibitorsforthemanagementofdiabetesmellitus:anopinionpaperfromtheEndocrineandMetabolismPracticeandResearchNetworkoftheAmericanCollegeofClinicalPharmacy.CurrentMedicalResearchandOpinion,2015;31(9),1733–1741.http://doi.org/10.1185/03007995.2015.1069739

4

10. CluckD,LewisP,DurhamSH,HesterEK.TheRiseandFallofEfavirenz.JournaloftheInternationalAssociationofProvidersofAIDSCare(JIAPAC),2016,2325957416629561.http://doi.org/10.1177/2325957416629561

11. MospanC,DeVeeC*,CluckD.PelvicInflammatoryDisease:StrategiesforTreatmentandPrevention.2016,fromhttps://www.uspharmacist.com/article/pelvic-inflammatory-disease-strategies-for-treatment-and-prevention

12. CovertKL,FlemingJN,StainoC,CasaleJP,BoyleKM,PilchNA,Taber,DJ.Predictingandpreventingreadmissionsinkidneytransplantrecipients.ClinicalTransplantation,2016;30(7),779–786.http://doi.org/10.1111/ctr.12748

13. GrayJ,Hagemeier,N,BrooksB,AlamianA.PrescriptionDisposalPractices:A2-YearEcologicalStudyofDrugDropBoxDonationsinAppalachia.AmericanJournalofPublicHealth,2015;105(9),e89-94.http://doi.org/10.2105/AJPH.2015.302689

14. HagemeierN,BlevinsS*,HagenK,SorahE*,ShahR*,FerrisK*.IntegrationofRuralCommunityPharmaciesintoaRuralFamilyMedicinePractice-BasedResearchNetwork:ADescriptiveAnalysis.INNOVATIONSinPharmacy,2015;6(3).Retrievedfromhttp://pubs.lib.umn.edu/innovations/vol6/iss3/12

15. HagemeierNE,AlamianA,MurawskiMM,FlippinH*,HagyEJ*,PackRP.CorrelatesofPrescriptionOpioidLegitimacyJudgmentsAmongCommunityPharmacists.SubstanceUse&Misuse,2016;51(6),692–699.http://doi.org/10.3109/10826084.2015.1135952

16. HagemeierNE,TudiverF,BrewsterS*,HagyEJ*,HagamanA,PackRP.Prescriptiondrugabusecommunication:Aqualitativeanalysisofprescriberandpharmacistperceptionsandbehaviors.ResearchinSocial&AdministrativePharmacy:RSAP,2015.http://doi.org/10.1016/j.sapharm.2015.12.008

17. HarirforooshS,StewartDW.Adescriptiveinvestigationoftheimpactofstudentresearchprojectsarisingfromelectiveresearchcourses.BMCResearchNotes,2016;9.http://doi.org/10.1186/s13104-016-1865-1

18. HessR.(2016).NewTherapiesforType1Diabetes.InNewTherapiesforType1Diabetes.(Book1-Endocrinologic/RheumatologicCare.,pp.35–57).Lenexa,KS:AmericanCollegeofClinicalPharmacy.

19. HessR,BrandonS,JohnsonFP.EffectivenessofPharmacistandPhysicianCollaborationintheTreatmentofType2DiabeteswithSevereInsulinResistanceUsingU-500Insulin.SouthMedJ,2016;InPress.

20. HessR,HagemeierNE,BlackwelderR,RoseD*,AnsariN*,BranhamT*.TeachingCommunicationSkillstoMedicalandPharmacyStudentsThroughaBlendedLearningCourse.AmericanJournalofPharmaceuticalEducation,2016;80(4),64.http://doi.org/10.5688/ajpe80464

21. HessR,RenfroC*.(2016).AComparativeAnalysisofPharmacists’Self-ConfidenceBeliefsforRegularU-500(concentrated)InsulinandU-100Insulin.JDiabetolEndocrinol,1(1),5–8.

5

22. InterprofessionalTeamDevelopmentinStudent-LedClinicsinRuralNortheastTennessee.(2016).InternationalJournalofHealthSciencesEducation.,InPress.

23. KarpenSC,HagemeierNE.(2016).AssessingFacultyandStudentInterpretationsofAACPSurveyItemswithCognitiveInterviewing.AmericanJournalofPharmaceuticalEducation.,InPress.

24. LeBlancB*,MeltonST.(2015).SAMSHAOpioidOverdosePrevention:TheRoleofOverdoseEducationandNaloxoneDistributionforPharmacists.PostgraduateInstituteforMedicine(PIM)forOnlineWebLesson.,November.

25. LindquistD**,BurchetteJE,OdleB,CluckD.NewAntibiotics-OldProblems.IntJPharmPract,InPress.

26. ManningDH,FerenceKA,Welch,AC,Holt-MaceyM.Developmentandimplementationofpass/failgradingsystemforadvancedpharmacypracticeexperiences.CurrentsinPharmacyTeachingandLearning,2016;8(1),59–68.http://doi.org/10.1016/j.cptl.2015.09.002

27. MeltonST.(2015a,October1).Whatistheroleoftopiramateinthetreatmentofalcoholusedisorders?MedscapeAsktheExperts.Retrievedfromhttp://www.medscape.com/viewarticle/851686

28. MeltonST.(2015b,November23).$5Insanity:ANewDrugofAbuse.MedscapeAsktheExperts.Retrievedfromhttp://www.medscape.com/viewarticle/854616

29. MeltonST,&OrrR.(2015).DetectionandDeterrenceofPrescriptionDrugAbuseandMisuseinDentalPractice.1stedition.Ed.O’NeilM.July2015.(1sted.).

30. MillerML,KarwaR,SchellhaseEM,PastakiaSD,CroweS,ManjiI,MainaM.MeetingtheNeedsofUnderservedPatientsinWesternKenyabyCreatingtheNextGenerationofGlobalHealthPharmacists.AmericanJournalofPharmaceuticalEducation,2016;80(2),22.http://doi.org/10.5688/ajpe80222

31. MospanC,AlexanderK.DevelopmentandImplementationofCharitablePharmacyServiceswithinaFederally-QualifiedHealthCenter(FQHC).INNOVATIONSinPharmacy,2015;6(3).Retrievedfromhttp://pubs.lib.umn.edu/innovations/vol6/iss3/4

32. MospanC,CluckD.PreventionandManagementofGenitalHerpes.RetrievedSeptember27,2016,fromhttps://www.uspharmacist.com/article/prevention-and-management-of-genital-herpes

6

33. MurrellD**,BossaerJB,CaricoR*,HarirforooshS,CluckD.Isavuconazoniumsulfate:atriazoleprodrugforinvasivefungalinfections.TheInternationalJournalofPharmacyPractice,2016.http://doi.org/10.1111/ijpp.12302

34. NelsonB.InsulinDeliveryinType2Diabetes:ToPumporNottoPump?RetrievedSeptember28,2016,fromhttp://www.iforumrx.org/node/293

35. NelsonB**,CluckD,AlexanderK.,UnderwoodRF,CrossLB.Needforawarenessaboutinteractionbetweennonprescriptionintranasalcorticosteroidsandpharmacokineticenhancers.AmericanJournalofHealth-SystemPharmacy:AJHP:OfficialJournaloftheAmericanSocietyofHealth-SystemPharmacists,2015;72(13),1086–1088.http://doi.org/10.2146/ajhp150179

36. PackRP,HagamanAM,WarfieldS,GrayJA,TudiverFG,AlamianA,HagemeierNE..InterprofessionalResearch,TrainingandOutreach:TheETSUPrescriptionDrugAbuse/MisuseWorkingGroup.InternationalJournalofHealthSciencesEducation2016;3(2),1–11.

37. RicketAL**,StewartDW,WoodRC,CornettL,OdleB,CluckD,El-BazouniH.ComparisonofPostoperativeBleedinginTotalHipandKneeArthroplastyPatientsReceivingRivaroxabanorEnoxaparin.TheAnnalsofPharmacotherapy,2016;50(4),270–275.http://doi.org/10.1177/1060028015626435

38. ShahD,BrownS,HagemeierN,ZhengS,KyleA,PryorJ,SinghP.Predictorsofneonatalabstinencesyndromeinbuprenorphineexposednewborn:cancordbloodbuprenorphinemetabolitelevelshelp?SpringerPlus,2016,5(1),854.http://doi.org/10.1186/s40064-016-2576-8

39. SnyderME,FrailCK,GernantSA,BacciJL,ColeyKC,ColipLM,HagemeierNE,SmithRB.Fellowshipsincommunitypharmacyresearch:Experiencesoffiveschoolsandcollegesofpharmacy.JournaloftheAmericanPharmacistsAssociation:JAPhA,2016;56(3),316–322.http://doi.org/10.1016/j.japh.2015.11.015

40. WallsZF,BossaerJB,CluckD.Usingscientificinquirytoincreaseknowledgeofvaccinetheoryandinfectiousdiseases.EducationforHealth(Abingdon,England),2016,29(2),95–106.http://doi.org/10.4103/1357-6283.188743

41. WoodRC,StewartDW,SlusherL*,El-BazouniH,CluckD,FreshourJ,OdleB.RetrospectiveEvaluationofPostoperativeBleedingEventsinPatientsReceivingRivaroxabanAfterUndergoingTotalHipandTotalKneeArthroplasty:ComparisonwithClinicalTrialData.Pharmacotherapy,2015;35(7),663–669.http://doi.org/10.1002/phar.1608

7

PharmaceuticalSciencesDepartmentalPresentationsandAbstracts2015-2016

1. S.D.Brown,P.O.Lewis,L.M.Kirk*,Y.Luu*,“STABILITYOFCOMMERCIALLY-AVAILABLEGRAPEANDCOMPOUNDEDCHERRYORALVANCOMYCINPREPARATIONSSTOREDINSYRINGESANDCUPS.”2015AmericanAssociationofCollegesofPharmacy,NationalHarbor,MD,July2015

2. S.D.Brown,N.E.Hagemeier,D.L.Hurley,R.A.Lugo,D.S.Roane,L.D.Calhoun,“ENGAGINGPHARMDSTUDENTSTHROUGHACONCENTRATIONINPHARMACYRESEARCHPROGRAM.”2015AmericanAssociationofCollegesofPharmacy,NationalHarbor,MD,July2015

3. J.Carmical*,A.R.Kyle*,D.Shah*,S.D.Brown,“EFFECTOFPHOSPHOLIPIDREMOVALONTHEDETERMINATIONOFBUPRENORPHINE,NORBUPRENORPHINE,METHADONE,ANDGLUCURONIDECONJUGATESINUMBILICALCORDPLASMA.”2015ASHPMid-YearMeetingandClinicalExposition,NewOrleans,LA,December2015

4. Y.Luu*,J.Thigpen,S.D.Brown,“STABILITYOFSILDENAFILINCOMBINATIONWITHHEPARINANDDOPAMINE.”2015ASHPMid-YearMeetingandClinicalExposition,NewOrleans,LA,December2015

5. L.M.Kirk*,Y.Luu*,S.D.Brown,P.O.Lewis,“VALIDATEDCHROMATOGRAPHICMETHODFORAPPLICATIONTOWARDTHEBEYOND-USE-DATEDETERMINATIONOFTWOLIDOCAINECONTAININGMOUTHWASHPREPARATIONS.”2015ASHPMid-YearMeetingandClinicalExposition,NewOrleans,LA,December2015

6. LorenKirk*,StacyBrown,YaoLuu*,AmandaOgle*,JessicaHuffman*,PaulLewis,“BEYONDUSEDATEDETERMINATIONOFLIDOCAINE-CONTAININGMAGICMOUTHWASHPREPARATIONS,”2016AppalachianStudentResearchForum

7. JessicaHuffman*,AmandaOgle*,StacyBrown,PaulLewis,“STABILITYSTUDYOFCOMPOUNDEDPYRIMETHAMINEORALSUSPENSIONS”2016AppalachianStudentResearchForum

8. KerriKochelek*,LaurenStrange*,RobKeasling*,StacyBrown,BrooksPond,“THEPHARMACOKINETICPROFILEOF“BATHSALTS”INMATERNALBRAIN,MATERNALPLASMA,PLACENTA,ANDFETALBRAIN,”2016AppalachianStudentResearchForum

9. SergioAlonso*,MatthewWalker*,DylanHayes*,CharlesCollins.ACTIVECONTENTOFVITAMIND3SUPPLEMENTS;ETSUAppalachianStudentResearchForum(April6-7,2016)Thisposterwasawardedfirstplaceinitscategory.

10. H.V.Oakes**,C.Devee*,B.Farmer*,S.Allen-Campbell**,A.Johnson*,M.Ketron*,A.Hanley,andB.B.Pond.(2016)NEUROGENESISWITHINTHEDENTATEGYRUSAFTERCHRONICTHERAPEUTICORABUSIVEDOSESOFMETHYLPHENIDATE.AppalachianStudentResearchForum,JohnsonCity,TN.(1stplacewinner,posterpresentations)

11. S.Shepard*,S.Rednour*,S.Allen-Campbell*,A.Hanley,andB.B.Pond(2016)NEUROCHEMICALOUTCOMESFOLLOWINGINDIVIDUALANDCOMBINEDSYNTHETICCATHINONEEXPOSURE.AppalachianStudentResearchForum,JohnsonCity,TN.

8

12. K.Johnson*,M.M.Ketron*,H.V.Oakes**,S.Allen-Campbell**,A.Hanley,andB.B.Pond(2016)PROMOTIONOFNEUROGENESISANDNEURONALSURVIVALWITHINTHEHIPPOCAMPUSBYLONG-TERMMETHYLPHENIDATETHERAPY.AppalachianStudentResearchForum,JohnsonCity,TN.

13. S.A.Allen**,H.V.Oakes**,S.Rednour*,S.Shepard*,andB.B.Pond(2016)NEUROCHEMICALOUTCOMESFOLLOWINGINDIVIDUALANDCOMBINEDSYNTHETICCATHINONEEXPOSURE.ExperimentalBiology,SanDiego,CA..

14. SHarirforoosh(InvitedPresentation)PHARMACOGENOMICSOFHIVMEDICATIONS.Symposium#5.2015AmericanCollegeofClinicalPharmacologyAnnualMeeting.SanFrancisco,California.September28,2015.

15. DerekE.Murrell**,HannahV.Oakes**,JessicaA.Coleman*,AngelaV.Hanley,KennyW.Bullins,GregA.Hanley,andSHarirforoosh.EFFECTOFALISKIRENNANOFORMULATIONONRATKIDNEYFUNCTION.2016SocietyofToxicologyAnnualMeetingandExposition.NewOrleans,LA.March2016

16. CrystalL.Whitted**,AngelaV.Hanley,KennethW.Bullins,DerekE.Murrell**,VictoriaE.Palau,RubenTorrenegra,SHarirforoosh.PHARMACOKINETICSOF5,7-DIHYDROXY-3,6,8-TRIMETHOXY-2-PHENYL-4H-CHROMEN-4-ONEINRATS.2015AmericanAssociationofPharmaceuticalScientistsAnnualMeetingandExposition.Orlando,FL.October2015

17. SHarirforoosh,DustinL.Cooper**,DerekE.Murrell**,JamesW.Denham,PCPanus,AngelaV.Hanley,KennyW.Bullins,andGregA.HanleyEVALUATIONOFKIDNEYHISTOPATHOLOGYANDRENALDRUGCONCENTRATIONOFCELECOXIBLOADEDPOLYLACTIC-CO-GLYCOLICNANOPARTICLESINRATS.2015AmericanAssociationofPharmaceuticalScientistsAnnualMeetingandExposition.Orlando,FL.October2015

18. SHarirforoosh,DustinL.Cooper**,DerekE.Murrell**,JamesW.Denham,PCPanus,AngelaV.Hanley,KennyW.Bullins,andGregA.Hanley.EFFECTOFDICLOFENACLOADEDPOLYLACTIC-CO-GLYCOLICNANOPARTICLESONKIDNEYHISTOPATHOLOGYINRATS.2015AmericanAssociationofPharmaceuticalScientistsAnnualMeetingandExposition.Orlando,FL.October2015

19. DustinL.Cooper**,AngelaV.Hanley,KennyW.Bullins,GregA.Hanley,JenniferL.Hoard,JessicaM.Coleman,andSHarirforoosh.ASSESSMENTOFRELATIVEBIOAVAILABILITYOFDICLOFENACLOADEDPOLY(LACTIDE-CO-GLYCOLIDE)NANOPARTICLESAFTERORALADMINISTRATION(posterpresentation).2015AmericanCollegeofClinicalPharmacologyAnnualMeeting.SanFrancisco,CA.September2015

20. DannyR.Pate*,KMueller,D.L.HURLEY.ADDITIONOFLIRAGLUTIDE3MGTOLIFESTYLEMODIFICATIONCOUNSELINGMAYREDUCEWEIGHTINOBESEADULTSWITHOUTDIABETES.Poster#167AtTheAppalachianStudentResearchForum,EastTennStateUniv.,April2016.

21. AnaCombs*,NicoleHawks*,ZacHoward*,T.J.Howell*,JaclynJordan*,HannahE.M.Martinez*,CodyPeeler*,AlexaPuswicz,CaseyTaylor*,JustinTaylor*,CaitlynWaldroup*,DavidL.Hurley.PHYLOGENETICANDEXPRESSIONANALYSISOFRATZN-16PROTEINACTIONIN

9

SOMATOTROPHCELLLINESTOSTUDYTISSUE-SPECIFICTRANSCRIPTIONOFTHEGROWTHHORMONEGENE.Poster#162atTheAppalachianStudentResearchForum,EastTennStateUniv.,April2016.

22. JarrettJM,Annor-GyamfiJK,WhittedC**,PalauVE,ShilabinAG.SYNTHESISANDIN-VITROCELLVIABILITY/CYTOTOXICITYSTUDIESOFNOVELPYRROLOBENZODIAZEPINES.PosterpresentationatTheCapitolEvent;Nashville,TN;February2016

23. CrossK,PalauVE,BrannonM,LightnerJ,DycusM,StoneW,KrishnanK.DELTA-TOCOTRIENOLANDSIMVASTATININDUCECYTOTOXICITYANDSYNERGYINBRAFMUTANTSK-MEL-28BUTNOTINWILDTYPEBRAFSK-MEL-2MELANOMACANCERCELLS.AACRAnnualMeeting,NewOrleans,LA,April2016.

24. RoseA,WannD,LightnerJ,BrannonM,StoneW,PalauVE,KrishnanK.METFORMINSUPPRESSESSYNTHESISOFPROSURVIVALSPHINGOLIPID,SPHINGOSINE-1-PHOSPHATE,BYINHIBITIONOFSPHINGOSINEKINASE-1INMCF-7ANDSK-BR-3BREASTCANCERCELLLINES.AACRAnnualMeeting,NewOrleans,LA,April2016.

25. TurnerB*,IkeleL*,LiuYC*,AbbottM*,WhittedC**,TorrenegraRD,RodriguezJ,PalauVE.EFFECTOFGNAPHALINONCELLADHESIONPROTEINSINPANCREATICANDCOLONCANCERCELLLINES.AppalachianStudentResearchForum,JohnsonCity,TNApril2016

26. WhittedCL**,CartwrightBM,WallsZ,ZouY,TorrenegraRD,andPalauVE.TWOISOMERICFLAVONESAND5-FLUOROURACILHAVEASYNERGISTICEFFECTINCOLONCANCERCELLSWHENUSEDINCOMBINATIONWITH5-FLUOROURACILDUETOINCREASEDDNADAMAGE.AppalachianStudentResearchForum,JohnsonCity,TNApril2016

27. CrossK,PalauVE,BrannonM,LightnerJ,DycusM,StoneW,KrishnanK.DELTA-TOCOTRIENOLANDSIMVASTATININDUCECYTOTOXICITYANDSYNERGYINBRAFMUTANTSK-MEL-28BUTNOTINWILDTYPEBRAFSK-MEL-2MELANOMACANCERCELLS.AppalachianStudentResearchForum,JohnsonCity,TNApril2016

28. RoseA,WannD,LightnerJ,BrannonM,StoneW,PalauVE,KrishnanK.METFORMINSUPPRESSESSYNTHESISOFPROSURVIVALSPHINGOLIPID,SPHINGOSINE-1-PHOSPHATE,BYINHIBITIONOFSPHINGOSINEKINASE-1INMCF-7ANDSK-BR-3BREASTCANCERCELLLINES.AppalachianStudentResearchForum,JohnsonCity,TNApril2016

29. SypniewskiB*,BrownJ*,AbiaI*,MastersM*,PalauVE,andWallsZF.ACTIVATABLESUBCELLULARTARGETINGOFMODULARPEPTIDETOTHESECRETORYORGANELLESOFBREASTCANCERCELLS.AppalachianStudentResearchForum,JohnsonCity,TNApril2016

30. PalauVE(InvitedSeminar)COMPOUNDSOBTAINEDFROMANDEANPLANTSWITHANTINEOPLASTICACTIVITYD.AnnualSeminarDepartmentofGraduateStudiesPontificiaUniversidadJaverianaBogota,Colombia2015

31. PalauVE(InvitedSeminar)COMPOUNDSOBTAINEDFROMANDEANPLANTSWITHANTINEOPLASTICACTIVITYSTRUCTURE-FUNCTIONACTIVITY.DepartmentofScienceandTechnologyUniversidaddeCienciasAplicadasyAmbientalesBogota,Colombia2015

10

32. PalauVE(InvitedSeminar)COMPOUNDSOBTAINEDFROMANDEANPLANTS:STRUCTURE–ACTIVITYRELATIONSHIPS.DepartmentofChemistryNovaSoutheasternUniversityFtLauderdale,FL2016

33. PeterC.Panus,JakeO’DellandJoshuaGeorgeUSEOFAQUANTITATIVEDRUGINDEXTOQUANTIFYDRUGSRELEVANTTOFALLRISKINCOMMUNITY-DWELLINGOLDERADULTS.AbstractwaspresentedatCombinedSectionsMeetingoftheAPTAfor,February17–20,2016.Poster1094

Textbooks

The2ndeditionofthetextbookentitled"PharmacologyforthePhysicalTherapist"forMcGraw-HillpublisherswillbeginrevisioninJune,2016,withacompletiondateofAugust2018.TheeditorialpositionshavechangedwithErinJobstasfirstauthorandPeterC.Panuswillbe2ndauthor.Contracthasbeensignedbyallparties.

PharmacyPracticeDepartmentalPresentationsandAbstracts2015-2016

Dataisinprocessofbeingcollected

College (Both Departments) Peer-Reviewed Publications – 2014-15 GCOP Faculty in Bold, PharmD students*, Other students**, Graduate students underlined

1. Peter C. Panus, David W. Stewart, Nicholas E. Hagemeier, Jim C. Thigpen, Lauren Brooks. Impact of self-testing frequency on exam scores in a pathophysiology course: a subgroup analysis. Am J Pharm Educ. 2014 Nov 15;78(9):165.

2. Crystal Whitted, Victoria Palau, Ruben Torrenegra, and Sam Harirforoosh. 2015. Development of reversed-phase high performance liquid chromatography methods for quantification of two isomeric flavones and the application of the methods to pharmacokinetic studies in rats. Journal of Chromatography B. 1001:150-155 http://dx.doi.org/10.1016/j.jchromb.2015.07.039

3. Uta B. Schambra, Jeff Goldsmith, Kevin Nunley, Yali Liu, Sam Harirforoosh, and Heidi M. Schambra. 2015. Low and moderate prenatal ethanol exposure of mice during gastrulation or neurulation delays neurobehavioral development. Neurotoxicology and Teratology. S0892-0362(15)30012-X. http://dx.doi.org/10.1016/j.ntt.2015.07.003

4. Derek E. Murrell, James W. Denham, and Sam Harirforoosh. 2015. Histopathology and Oxidative Stress Analysis of Concomitant Misoprostol and Celecoxib Administration. Journal of Toxicologic Pathology. 28: 165–170

5. Dustin L. Cooper, Derek E. Murrell, David S. Roane, and Sam Harirforoosh. 2015. Effects of formulation design on niacin therapeutics: mechanism of action, metabolism, and drug delivery. International Journal of Pharmaceutics. 490(1-2):55-64. http://dx.doi.org/10.1016/j.ijpharm.2015.05.024

11

6. Derek E. Murrell, Jonathan P. Moorman, and Sam Harirforoosh. 2015. Stribild: a review of component characteristics and combination drug efficacy. European Review for Medical and Pharmacological Sciences. 19: 904-914

7. Dustin L. Cooper and Sam Harirforoosh. 2014. Effect of formulation variables on preparation of celecoxib loaded polylactide-co-glycolide nanoparticles. PLoS ONE 9(12): e113558. http://dx.plos.org/10.1371/journal.pone.0113558

8. Rogers M, Kalra S, Moukharskaya J, Chakraborty K, Niyazi M, Krishnan K, Lightner J, Brannon, M, Stone WL, Palau VE 2015. Synergistic growth inhibition of PC-3 prostate cancer cells with low-dose combinations of Simvastatin and Alendronate. Anticancer research;35(4):1851-9M. K. Pickering,* S.D. Brown, “Assays for determination of ertapenem for applications in therapeutic drug monitoring, pharmacokinetics, and sample stability.” Biomedical Chromatography. 28: 1525-1531, 2014.

9. D. Stallard,* S. Brown, “Comparing HPLC stationary phases for the separation of six compounds used in pain management: is there a viable alternative to C18?”Journal of Diagnostic Techniques & Biomedical Analysis; 2(2): 2014.

10. A.R. Kyle,* J. Carmical,* D. Shah,* J. Pryor,* S. Brown, “UHPLC-MS/MS quantification of buprenorphine, norbuprenorphine, methadone, and glucuronide conjugates in umbilical cord plasma.” Biomedical Chromatography. Accepted: February 2015; Article first published online: 22 MAR 2015, DOI: 10.1002/bmc.3460

11. J. Bentley,* F. Snyder,* S. Brown, R. Brown, B. Pond, “Sex differences in d,l-methylphenidate kinetics.” European Review for Medical and Pharmacological Sciences. Accepted: February 2015

12. L.M. Kirk,* S.D. Brown, “Beyond-use date determination of buprenorphine buccal solution using a stability-indicating high-performance liquid chromatographic assay.” Journal of Feline Medicine and Surgery. Accepted: December 2014; Published online before print: February 13, 2015, doi:10.1177/1098612X15569329

13. C. Garst,* S.D. Brown, M. Fulmer, D. Thewke, “Optimized Extraction of 2-Arachidonyl Glycerol and Anandamide from Aortic Tissue and Plasma for Quantification by LC-MS/MS.” European Journal of Lipid Science and Technology. Accepted: June 2015

14. 15. Walls ZF, Varghese Gupta S, Amidon GL, Lee KD. “Synthesis and Characterization of Valyloxy Methoxy Luciferin for the Detection of Valacyclovirase and Peptide Transporter”. Bioorg Med Chem Lett. 2014

15. S. A. Allen and B. B. Pond (2014) Chromatographic and electrophoretic strategies for the chiral separation and quantification of d- and l-threo methylphenidate in biological matrices. Biomedical Chromatography, 28: 1554-64.

16. Mospan CM. Consideration of Proton Pump Inhibitor (PPI) Warning in Treating Gastroesophageal Reflux Disease (GERD). JAAPA 2015 (in press).

17. Mospan CM, Leonard C, Alley K. Afrezza®: What is its Place in Insulin Therapy? JAAPA 2015 (in press).

18. Mospan CM. Statins and Cognitive Function: Protective or Harmful? JAAPA. Submitted 2015 (in

12

press).

19. Wood RC 3rd, Stewart DW, Slusher L*, El-Bazouni H, Cluck D, Freshour J, Odle B. Retrospective Evaluation of Postoperative Bleeding Events in Patients Receiving Rivaroxaban After Undergoing Total Hip and Total Knee Arthroplasty: Comparison with Clinical Trial Data. Pharmacotherapy. 2015 Jul;35(7):663-9. doi: 10.1002/phar.1608. Epub 2015 Jun 19.

20. Nelson B, Cluck D, Alexander K, Underwood RF, Cross LB. Need for awareness about interaction between nonprescription intranasal corticosteroids and pharmacokinetic enhancers. Am J Health Syst Pharm. 2015 Jul 1;72(13):1086-8. doi: 10.2146/ajhp150179.

21. Bossaer J, Panus P, Stewart DW, Hagemeier NE, George J. Student Performance in a Pharmacotherapy Oncology Module Before and After Flipping the Classroom. American Journal of Pharmaceutical Education 2015 (in press).

22. Gray JA, Hagemeier NE, Brooks B, Alamian AA. Prescription waste and disposal practices: A two-year ecological study of drug drop box donations in Appalachia. American Journal of Public Health 2015 (in press).

23. Hagemeier NE, Alamian AA, Murawski MM, Pack RP. Factors associated with provision of addiction treatment facility information by community pharmacists. Journal of Substance Abuse Treatment. 2015; 52: 67-72. Early online November 2014.

24. Hagemeier NE, Hess R, Hagen KS, Sorah EL*. Impact of an interprofessional communication course on nursing, medical and pharmacy students' communication skill self-efficacy beliefs. American Journal of Pharmaceutical Education. 2014; 78(10): Article 186.

25. Panus PC, Stewart DW, Hagemeier NE, Thigpen JC, Brooks L. A Subgroup Analysis of the Impact of Self-testing Frequency on Examination Scores in a Pathophysiology Course. American Journal of Pharmaceutical Education. 2014; 78(9): Article 165.

26. Nelson B, Hess R. Insulin Delivery in Type 2 Diabetes Mellitus: To Pump or Not to Pump? iForumRx.org (in press).

27. Bossaer JB, Chakraborty K. Drug interaction between idelalisib and diazepam resulting in altered mental status and respiratory failure. J Oncol Pharm Pract 2015 (in press).

28. Stewart DW, Rikye S, Odle B, Bossaer JB, Flores EK. Use of anticoagulation in patients with active cancer: a single center retrospective analysis. J Hematol Oncol Pharm. 2014;4(4):110-114.

29. Alexander KM, Divine HS, Hanna CR, Gokun Y, Freeman PR. Implementation of Personalized Medicine Services in Community Pharmacies: Perceptions of Independent Community Pharmacists. J Am Pharm Assoc 2014; 54(5):510-517.

30. Alexander K. Children's Allergy OTC Medications and the Use of Proper Dosing Devices. Student Pharmacist Magazine (APhA) 2015 (in press).

31. Mospan C, Alexander K. Development and Implementation of Charitable Pharmacy Services within a Federally-Qualified Health Center (FQHC). Innovations in Pharmacy 2015 (in press).

32. Stewart DW, Rikhye S, Odle B, Bossaer J, Flores EK. Prescribing of Low-Molecular-Weight

13

Heparin and Warfarin in Patients with Acute Venous Thromboembolism and Active Cancer. J Hematol Oncol Pharm 2014; 4(4): 110-114.

33. Thigpen J, Melton ST. Neonatal abstinence syndrome: a challenge for medical providers, mothers, and society. J Pediatr Pharmacol Ther. 2014 Jul;19(3):144-6. Thigpen J, Melton ST. Neonatal abstinence syndrome: a challenge for medical providers, mothers, and society. J Pediatr Pharmacol Ther. 2014 Jul;19(3):144-6.

34. Begley KJ, Monaghan MS, Clavier CW, Lugo RA, Crouch MA. Technology in the Pharmacy Learning Environment: Survey of Use and Misuse. Innovations in Pharmacy 2015: 6(1); Article 186.

35. Ward RM, Drover DR, Hammer GB, Stemland CJ, Kern S, Tristani-Firouzi M, Lugo RA, Satterfield K, Anderson BJ. The pharmacokinetics of methadone and its metabolites in neonates, infants, and children. Pediatr Anesth 2014: 24:591-601.

College Non-Peer-Reviewed Articles - 2014-15

GCOP Faculty in Bold, PharmD students*, Other students**, Graduate students underlined

1. Panus P. “Drug Associated Falls”. Michigan Health and Rehabilitation Services and the Home Rehabilitation Services of Michigan. Troy, MI. 3/7/2015

2. Mospan CM. Using our Earthly Endeavors to Serve Patients. Christianity & Pharmacy; 2015 (Special Missions Issue) (in press).

3. Mospan CM. Bouncing back from burnout. Student Pharmacist. May/June 2015;11(5):18.

4. Bossaer JB. Addressing potential interactions between antineoplastics and dietary supplements (letter). Am J Health Syst Pharm. 2015;72(11)915-6.

5. Johnson M, Gaddy J, Dunkerson K, Alexander K, Dalle-Ave M. Implementing an Interdisciplinary Community-based Health Intervention in a Rural Setting. Tennessee Family Physician. 2014; 7(3): 19-20.

6. Stewart DW. Reflections on influencing the next generation of pharmacists (letter). Am J Pharm Educ 2015 (in press).

14

College Peer-Reviewed Book Chapters – 2014-15 GCOP Faculty in Bold, PharmD students*, Other students**, Graduate students underlined

1. Florence JA, Flores EK. (2015). Hypoglycemia, Diabetic. In Domino FJ (Ed.), The 5-Minute Clinical Consult 2016, Philadelphia: Wolters Kluwer Health.

2. Sisson E, Calhoun M. Dyslipidemia: Contemporary Evaluation and Management. American Society of Health-System Pharmacists, 2015. eBook.

3. Melton ST. Anxiety Disorders. College of Psychiatric and Neurologic Pharmacist Review Course for Board Certification in Psychiatric Pharmacy. In press (January 2016)

4. Melton ST. Treatment Resistant Generalized Anxiety Disorder: A Case of the Intolerable Adjunctive. In: Chavez B, Grady SE, McGuire JM, Nelson LA, editors. Psychiatric Pharmacotherapy Case Series. Lincoln NE): College of Psychiatric and Neurologic Pharmacists; 2015. 32p. Available from http://cpnp.org/ed/case/2015/gad-3 .

5. Melton ST, Orr R. Detection and Deterrence of Prescription Drug Abuse and Misuse in Dental Practice. American Dental Association Practical Guide to Substance Use Disorders and Safe Prescribing, 1st edition. Ed. O'Neil M. July 2015.

6. Melton ST, Kirkwood CK. Insomnia, Drowsiness and Fatigue. Handbook of Nonprescription Drugs: An Interactive Approach to Self-Care.,18th edition. Eds. Berardi RR, Kroon LA, McDermott JH, et al. December 2014.

15

College Presentations – 2014-15 GCOP Faculty in Bold, PharmD students*, Other students**, Graduate students underlined

1. Mospan CM. (2015). Utilizing the flipped classroom to create critical thinking in home monitoring recommendations. AACP Self-Care Therapeutics/Non-prescription Medicines Special Interest Group Newsletter. Retrieved from: http://www.aacp.org/governance/SIGS/selfcarenonprescriptionmedicine/Documents/AACP%20Self%20Care%20SIG%20Newsletter%202015%20final.pdf.

2. Panus P, Barnhart R. Physical Therapy and Pharmacology Interactions in the Pediatric Patient. Submitted to Combined Sections Meeting of the APTA, Indianapolis, IN, 2/6/2015. (2 hour platform presentation).

3. Stewart DW, Panus P. Pharmacy curriculum outcomes assessment (PCOA) performance in relation to individual course level performance. American Association of Colleges of Pharmacy Annual Meeting. National Harbor, MD, July 11–15, 2015.

4. Harirforoosh S. GLP and GMP Requirements: What They Mean. Short course on Drug Development and Discovery by FDA Standards. 2014 American Association of Pharmaceutical Scientists Annual Meeting and Exposition. San Diego, California. November 2, 2014 (by invitation).

5. H. M. Trivett,* S. D. Brown, and B. B. Pond (2014) Quantitative determination of d- and l- enantiomers of methylphenidate in placenta and fetal brain tissue by liquid chromatography-mass spectrometry. American Society of Health-System Pharmacists, Anaheim, CA.

6. S. A. Allen, S. Rednour,* and B. B. Pond (2015) Alterations in brain tissue neurochemistry following chronic ‘bath salts’ exposure Experimental Biology, Boston, MA.

7. S. A. Allen, S. Rednour,* and B. B. Pond (2015) Alterations in brain tissue neurochemistry following chronic ‘bath salts’ exposure Appalachian Student Research Forum, Johnson City, TN. (2nd place winner, poster presentations).

8. H. M. Trivett,* S. D. Brown, and B. B. Pond (2015) Quantitative determination of d- and l- enantiomers of methylphenidate in placenta and fetal brain tissue by liquid chromatography-mass spectrometry. Appalachian Student Research Forum, Johnson City, TN. (1st place winner, oral presentations).

9. J. Peters,* R. Keasling,* S. D. Brown, and B. B. Pond. (2015) A method for quantification of “bath salts” in mouse brain tissue using liquid chromatography-mass spectrometry. Appalachian Student Research Forum, Johnson City, TN.

10. Whitted CL, Cooper DL, Palau VE, Torrenegra RD, Harirforoosh S. Development of a High Performance Liquid Chromatography Method for Quantification of a Flavone in Rat Plasma. Annual Meeting of the American Association of Pharmaceutical Scientists (AAPS), San Diego, CA November 2014.

11. Wann D, Palau V, Lightner J, Brannon M, Stone W, Krishnan K. Metformin decreases cellular ceramides in MCF-7 and MDA-MB 231 breast cancer cell lines by inhibition of ceramide synthetic enzymes. American Association of Cancer Research (AACR), Philadelphia, PA. April 2015.

16

12. Turner, B.* Ikele, L.,* Whitted, C., Torrenegra, R., Palau, VE. Gnaphalin a flavonoid derived from Gnaphalium gracile H.B.K. has a differential apoptotic effect on pancreatic cell lines. Appalachian Research Forum, Johnson City, TN April 2015.

13. Liu YC*, Irick C, Whitted CL, Torrenegra RD, Palau VE. Gnaphalin a flavonoid derived from Gnaphalium gracile H.B.K. has a differential cytotoxic effect on colon cell lines. Appalachian Research Forum, Johnson City, TN April 2015.

14. Pate D,* Claborn J,* Balic M,* Abbott M,* Torrenegra RD, Palau VE. Gnaphalin has preferential cytotoxic effects towards breast cancer MCF-7 and prostate androgen-dependent LnCaP cancer cell lines. Appalachian Research Forum, Johnson City, TN April 2015.

15. Bowen E, Davis S, Dixon E, Corbin M, Whitted CL, Torrenegra RD, Palau VE. Evaluation of Flavone P on Pancreatic Cancer Cell Lines. Appalachian Research Forum, Johnson City, TN April 2015.

16. Wann D, Palau V, Lightner J, Brannon M, Stone W, Krishnan K. Metformin decreases cellular ceramides in MCF-7 and MDA-MB 231 breast cancer cell lines by inhibition of ceramide synthetic enzymes. [abstract] In: Proceedings of the 106th Annual Meeting of the American Association for Cancer Research; 2015 Apr 18–22; Philadelphia (PA): AACR 2015.

17. Whitted CL, Cooper DL, Palau VE, Torrenegra RD, Harirforoosh S. Development of a High Performance Liquid Chromatography Method for Quantification of a Flavone in Rat Plasma. [abstract] In: Proceedings of the Annual Meeting of the American Association of Pharmaceutical Scientists; 2014 Nov 2-6; San Diego (CA):AAPS 2014.

18. S.D. Brown, P.O. Lewis,* L.M. Kirk,* Y. Luu,* “Stability of commercially-available grape and compounded cherry oral vancomycin preparations stored in syringes and cups.” 2015 American Association of Colleges of Pharmacy, National Harbor, MD, July 2015.

19. S.D. Brown, N. E. Hagemeier, D. L. Hurley, R. A. Lugo, D. S. Roane, L. D. Calhoun, “Engaging PharmD Students through a Concentration in Pharmacy Research Program.” 2015 American Association of Colleges of Pharmacy, National Harbor, MD, July 2015.

20. S. Brown, M. Borketey, S. Campbell, “LC-MS-MS Determination of Arachidonic Acid and Linoleic Acid Product Profiles in Colon Cancer Cells.” Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy, New Orleans, LA, March 2015.

21. J. Pryor, S. Piyush, D. Nilesh, A. Redmond,* S. Brown, and D. Shah,* “Correlation of newborn’s clinical course with cord blood levels of buprenorphine, methadone, and their metabolites.” Pediatric Academic Societies (PAS) Annual Meeting, Vancouver, BC, Canada, May 2014; Encore presentation at the American Academy of Pediatrics (AAP) Annual Meeting, San Diego, CA, October 2014.

22. Loren Kirk,* Yao Luu,* Paul Lewis,* Stacy Brown, “STABILITY OF ORAL VANCOMYCIN PRODUCTS FOR BULK PREPARATION AND STORAGE,” Appalachian Student Research Forum (Won 2nd Place in Pharmacy/Medical Students Division).

17

23. Jennifer Carmical,* Amy Kyle,* Darshan Shah,* Stacy Brown, “EFFECT OF PHOSPHOLIPID REMOVAL ON THE DETERMINATION OF BUPRENORPHINE, NORBUPRENORPHINE, METHADONE, AND GLUCURONIDE METABOLITES IN UMBILICAL CORD PLASMA,” Appalachian Student Research Forum.

24. Bryan R. Gunter,* Kristen A. Butler,* Richard L. Wallace, Nakia Woodward, Steven M. Smith, and Sam Harirforoosh. NSAIDs-induced cardiovascular adverse effects: a meta-analysis (poster presentation). 2015 American Pharmacists Association Annual Meeting & Exposition. San Diego, CA. March 2015.

25. Crystal L. Whitted, Dustin L. Cooper, Victoria E. Palau, Ruben Torrenegra, and Sam Harirforoosh. A Reversed-phase high performance liquid chromatography method for the quantitative determination of a flavone in rat plasma (poster presentation). 2015 American Pharmacists Association Annual Meeting & Exposition. San Diego, CA. March 2015.

26. Jessica A. Coleman,* Dustin L. Cooper, and Sam Harirforoosh. Formulation and optimization of aliskiren loaded poly(lactide-co-glycolide) nanoparticles (poster presentation). 2015 American Pharmacists Association Annual Meeting & Exposition. San Diego, CA. March 2015.

27. Derek E. Murrell and Sam Harirforoosh. Analysis of concomitant rebamipide influence on celecoxib concentration in the rat liver (poster presentation). 2015 American Pharmacists Association Annual Meeting & Exposition. San Diego, CA. March 2015.

28. Derek E. Murrell, Yuyun Rahmasari,* John D. Harrell,* James W. Denham,* Kenneth W. Bullins, Angela V. Hanley, Peter C. Panus, and Sam Harirforoosh. An Examination of Hepatic Effects during Diclofenac or Celecoxib Administration in the Presence or Absence of Rebamipide (poster presentation). 2014 American Association of Pharmaceutical Scientists Annual Meeting and Exposition. San Diego, CA. November 2014.

29. Dustin L. Cooper, Angela V. Hanley, Kenny W. Bullins, Greg A. Hanley, Jessica M. Coleman,* and Sam Harirforoosh. Polylactic-co-glycolic nanoparticle encapsulation improves oral bioavailability of celecoxib in rats (poster presentation). 2014 American Association of Pharmaceutical Scientists Annual Meeting and Exposition. San Diego, CA. November 2014.

30. Dustin L. Cooper, Jennifer, A. Carmical,* Peter C. Panus, and Sam Harirforoosh. Effects of niacin loaded polymeric nanoparticles on in vitro prostaglandin expression (poster presentation). 2014 American Association of Pharmaceutical Scientists Annual Meeting and Exposition. San Diego, CA. November 2014.

31. Derek E. Murrell, Dustin L. Cooper, and Sam Harirforoosh. The effect of concomitant misoprostol on hepatic celecoxib concentration (poster presentation). 2014 American Association of Pharmaceutical Scientists Annual Meeting and Exposition. San Diego, CA. November 2014.

32. Derek E. Murrell and Sam Harirforoosh. A Quantitative Model for Prediction of Hepatic Diclofenac Concentration following a Single Oral Dose (poster presentation). The 5th American Conference on Pharmacometrics. Las Vegas, NV. October 2014.

33. Derek E. Murrell, John Harrell,* Yuyun Rahmasari,* Dustin L. Cooper, Angela V. Hanley, Kenneth W. Bullins, and Sam Harirforoosh. Evaluation of hepatic oxidative stress in rats following celecoxib and misoprostol concomitant administration (poster presentation). 2014

18

American College of Clinical Pharmacology Annual Meeting. Atlanta, GA. September 2014.

34. Dustin L. Cooper and Sam Harirforoosh. Characterization of PVA and DMAB based Celecoxib Loaded Polymeric Nanoparticles (poster presentation). 41st Annual Meeting & Exposition of the Controlled Release Society. Chicago, IL. July 2014.

35. Jennifer A. Carmical,* Dustin L. Cooper, Sam Harirforoosh. Formulation and Characterization of Niacin Loaded PLGA-Based Nanoparticles (poster presentation). 41st Annual Meeting & Exposition of the Controlled Release Society. Chicago, IL. July 2014.

36. Yao Luu,* Jim Thigpen, Stacy Brown, “STABILITY OF SILDENAFIL IN COMBINATION WITH HEPARIN AND DOPAMINE, Appalachian Student Research Forum.

37. Manis, JD,* Carver, HD,* Combs, A,* Hawks, BN,* Howell, TJ,* Jordan, J,* Martinez, HEM,* Peeler, C,* Puswicz, A,** Taylor, J,* and Hurley, DL. 2015. Expression cloning of rat Zn16 to examine differential N- and C-terminal functionality regulating transcription of the Growth Hormone gene. Poster presentation at the Appalachian Student Research Forum, April 9, 2015, Johnson City, TN.

38. SD Brown*, NE Hagemeier, DL Hurley, RA Lugo, DS Roane*, LD Calhoun. Engaging PharmD Students in the Concentration in Pharmacy Research Program at the Bill Gatton College of Pharmacy at ETSU. Symposium presentation at AACP Annual Meeting, Washington DC, June 2015.

39. Hagemeier NE, Alamian A, Murawski MM, Pack RP, Flippin H, Hagy EJ. Correlates of Prescription Opioid Legitimacy Estimations among Community Pharmacists in Tennessee. Presented at College on Problems of Drug Dependence Annual Meeting. Phoenix, AZ; June 2015.

40. Sevak RJ, Brooks B, Gray JA, Alamian A, Hagemeier NE, Pack RP. Yearly trends in controlled substances obtained via permanent drug donation boxes in Northeast Tennessee. Presented at College on Psychiatric and Neurologic Pharmacists Annual Meeting. Tampa, FL; April 2015.

41. Walker A, Warfield S, Blevins S, Holland M, Hagemeier NE. The role of Tennessee community pharmacists in preventing diabetes-related hospitalizations. Presented at East Tennessee State University Primary Care and Prevention Research Day. Johnson City, TN; February 2015.

42. Brooks B, Gray JA, Hagemeier NE, Alamian A. Permanent drug donation boxes address prescription substance abuse in Northeast Tennessee: A 30-month descriptive analysis. Presented at East Tennessee State University Primary Care and Prevention Research Day. Johnson City, TN; February 2015.

43. Gray JA, Brooks B, Alamian A, Hagemeier NE. An Ecological Study of Drug Drop Box Donations in Appalachia. Presented at American Public Health Association Annual Meeting and Exposition. New Orleans, LA; November 2014.

44. Hagemeier NE, Blevins S, Ferris K, Mubaslat R. Community Pharmacists' Willingness to Participate in a Rural Appalachian Practice-Based Research Network. Presented at North American Primary Care Research Group PBRN Conference. Bethesda, MD; July 2014.

19

45. Hagemeier NE, Melton S, Cross LB. Design, Implementation, and Evaluation of a Self-Awareness Focused Contemporary Pharmacy Practice Course. Presented at the American Association of Colleges of Pharmacy Annual Meeting. Grapevine, TX; July 2014.

46. Hagemeier NE, Gentry C, Cross LB, Rose D, Miller G, Phillips C. Student Pharmacists' Personal Finance Perceptions, Projected Student Loan Indebtedness, and Career Decision Making. Presented at the American Association of Colleges of Pharmacy Annual Meeting. Grapevine, TX; July 2014.

47. Gray JA, Melton ST, Hagemeier NE. Student Pharmacists Engaged to Address Prescription Substance Abuse in East Tennessee. Presented at the American Association of Colleges of Pharmacy Annual Meeting. Grapevine, TX; July 2014.

48. Hagemeier NE. Prescription Drug Abuse: Past, Present and Prevention. East Tennessee State University Tables of Content. Johnson City, TN; April 10, 2015.

49. Pack RP, Hagemeier NE, Brooks B. ETSU Diversity-Promoting Institutions Drug Abuse Research Program (DIDARP). ETSU Academic Health Sciences Center Prescription Drug Abuse Prescription Drug Abuse/Misuse Grand Rounds. Johnson City, TN; April 3, 2015. (CE event)

50. Hagemeier NE, Tudiver F. Comfort, Complexities, and Confrontation: Health Care Provider Communication and Prescription Drug Abuse and Misuse. 19th Annual Louis A Cancellaro Primary Care Conference. Johnson City, TN; March 25, 2015. (CE event)

51. Hagemeier NE, Tudiver F. ETSU DIDARP Project 1: Health Care Provider Communication and Prescription Drug Abuse and Misuse. 5th Annual AppNET Conference. Johnson City, TN; March 13, 2015 (CE event)

52. Click I, Hagemeier NE. Improving Tennessee Health Care Providers Understanding of Neonatal Abstinence Syndrome. 5th Annual AppNET Conference. Johnson City, TN; March 13, 2015 (CE event)

53. Phillips CE*, Hess R. Surveying Pharmacists' Confidence in Patient Counseling on the Safe Use of Regular U-500 (Concentrated) Insulin Compared With U-100 Insulin. Poster presented at 49th Annual American Society Health-System Pharmacists Midyear Clinical Meeting. Anaheim, CA 2014.

54. Hess R, Flores E. Comparison of Teaching Methods on Skin Disorders: Standardized Patients Dressed in Moulage Versus Paper Cases. Poster presented at American Association of Colleges of Pharmacy Annual Meeting. Grapevine, TX. 2014.

55. Bossaer JB, Panus P. Student performance in a pharmacotherapy oncology module before and after flipping the classroom. Am J Pharm Educ 2014;78(5) Article 111, page 78.American Association of Colleges of Pharmacy Annual Meeting July 2014. Grapevine, TX.

56. Adams CB, Street, DS, Bossaer JB. Incidence of cetuximab-related infusion reactions in Northeastern Tennessee.Hematology Oncology Pharmacy Association Annual MeetingMarch 2015. Austin, TX.

57. Adams CB, Street, DS, Bossaer JB. Incidence of cetuximab-related infusion reactions in

20

Northeastern Tennessee.American Society of Health-Systems Pharmacists Midyear Clinical Meeting December 2014. Anaheim, CA.

58. Calhoun M, Harris E. Developing Interprofessionalism: Integrating Students and Residents of Pharmacy and Medicine into an Interprofessional Practice. Interprofessional Education Conference, June 2015, Pigeon Forge, TN.

59. Ricket A, Cornett L, Wood R, Freshour J, Odle B, Cluck D, and Stewart DW. Comparison of "real-world" post-operative bleeding in THA and TAK patients receiving rivaroxaban or enoxaparin. Southeastern Residency Conference, April 2015. Athens, Georgia.

60. Ricket A, Cornett L, Wood R, Freshour J, Odle B, Cluck D, and Stewart DW. Comparison of "real-world" post-operative bleeding in THA and TAK patients receiving rivaroxaban or enoxaparin. American Society of Health-System Pharmacists Annual Midyear Clinical Meeting; December 2014. Anaheim, California.

61. Mullins CM, Stidham A, Lee M, Melton ST. Integrating a Clinical Fellows Framework and Interprofessional Model of Care. Poster Presentation at the 1st Annual Southeastern Education Conference. Music Road Resort, Pigeon Forge, TN. June 11, 2015.

62. Gray J, Hagemeier N, Melton ST. Prescription Drug Abuse Prevention in East Tennessee: Engaging Communities to Impact an Epidemic. Poster presentation at the 2014 Annual Meeting of the American Association of Colleges of Pharmacy, Grapevine, TX. July 26, 2014.

63. K Baker, KP Williams, R Blackwelder, B Cross, K Tillman. Interprofessional Education and Faculty Attitudes. Presented at the national IPEC conference in Washington, DC.

64. MC Hogue*, PC Panus, E Anson, J Jeka, ED Thompson, S Zheng, Z Walls, BL Odle. Quantitative Drug Index (QDI) Poster. ASHP 2014 MidYear Meeting.

65. Gray J, LeBlanc B*, Bare K*, Anthony A*. PRESCRIPTION DONATIONS INCREASED DURING DEA SPONSORED DRUG TAKE BACK EVENT: IMPACT OF MASS MARKETING. Journal of the American Pharmacists Association. 2015.Poster presented at the American Pharmacists Association Meeting, San Diego, California; March 27, 2015.

21

College Non-Peer-reviewed Newsletters – 2014-15 GCOP Faculty in Bold, PharmD students*, Other students**, Graduate students underlined

1. Mospan CM. (2015). Strategic planning for your career. American Pharmacists Association (New Practitioner Network). Retrieved from: http://www.pharmacist.com/strategic-planning-your-career.

2. Mospan CM. (2014). Giving the gift of hope. American Pharmacists Association (New Practitioner Network). Retrieved from: http://pharmacist.com/giving-gift-hope.

3. Mospan CM. (2014). The ins and outs of moving. American Pharmacists Association (New Practitioner Network). Retrieved from: http://www.pharmacist.com/node/790653?is_sso_called=1.

4. Morris, B, Mospan CM, Ung D, Lantaff W, Brown P. The resident is in. America's Pharmacist: Don't Stop Thinking About Tomorrow. July 2014: 28-31.

5. Mospan CM. (2014). Making a budget: utilizing online tools. American Pharmacists Association (New Practitioner Network). Retrieved from: http://www.pharmacist.com/how-make-budget-using-online-tools.

6. Mospan CM. A heart for volunteering. Student Pharmacist. May/June 2014;10(5):19.

College Online Publications – 2014-15

1. Melton ST. What is the role of topiramate in the treatment of alcohol use disorders? Medscape Ask the Experts. Accepted for publication online July 2015.

2. Melton ST. College of Psychiatric and Neurologic Pharmacists Substance Abuse Task Force. Naloxone Access:A Practical Guideline for Pharmacists. April 2015. Available at http://cpnp.org/_docs/guideline/naloxone/naloxone-access.pdf

3. Melton ST. Has gabapentin become a drug of abuse? Medscape Ask the Experts. July 14, 2014. Available at http://www.medscape.com/viewarticle/826680 .

4. B Nelson, A Simpson, LB Cross. Digoxin Use in Patients with Atrial Fibrillation - Should We Desist? iForumRx 2015.

College Letters/Editorials

1. Thigpen JT, Melton S. Neonatal Abstinence Syndrome: A Challenge for Medical Providers, Mothers, and Society (letter).Journal of Pediatric Pharmacology and Therapeutics2014;19(3):144-146.