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4/6/2012
1
Moshe Heller LAc.
Pervasive Development
Disorders PDD
� The term "pervasive development disorders"
(PDDs) refers to a group of conditions that
involve delays in the development of many
basic skills, most notably the ability to
socialize with others, to communicate and to
use imagination. Children with these
conditions often are confused in their
thinking and generally have problems
understanding the world around them
Pervasive Development Disorders
PDD
� Because these conditions typically are
identified in children around 3 years of age --
a critical period in a child's development --
they are called development disorders.
Although the condition begins far earlier than
3 years of age, parents often do not notice a
problem until the child is a toddler who is
not walking, talking or developing as well as
other children of the same age.
4/6/2012
2
There are five types of PDDs:
� Autism
� Asperger's syndrome
� Childhood disintegrative disorder
� Rett's syndrome
� Pervasive development disorder not
otherwise specified (PDDNOS)
Autism
� Children with autism have problems with
social interaction, pretend play and
communication. They also have a limited
range of activities and interests. Many
(nearly 75%) of children with autism also
have some degree of mental retardation.
� To Diagnose Autistic disorder requires
impairments in all three domains:
communication, social interaction and
repetitiveness
Asperger's syndrome
� Like children with autism, children with Asperger's syndrome have difficulty with social interaction and communication, and have a narrow range of interests. However, children with Asperger's have average or above average intelligence, and develop normally in the areas of language and cognition (the mental processes related to thinking and learning). Children with Asperger's often also have difficulty concentrating and may have poor coordination.
� Asperger’s disorder is distinguished by the lack of communication impairments and better-preserved intellectual functioning.
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Pervasive development disorder not
otherwise specified (PDD NOS)
� This category is used to refer to children who
have significant problems with
communication and play, and some difficulty
interacting with others, but are too social to
be considered autistic
� PDD NOS is diagnosed in cases when
diagnostic criteria for autistic or Asperger’s
disorders are not met.
Rett's syndrome
� Children with this very rare disorder have the symptoms associated with a PDD and also suffer problems with physical development. They generally suffer the loss of many motor, or movement, skills -- such as walking and use of their hands -- and develop poor coordination. This condition has been linked to a defect on the X chromosome, so it almost always affects girls
Childhood disintegrative
disorder
� Children with this rare condition begin their
development normally in all areas, physical
and mental. At some point, usually
between 2 and 10 years of age, a child with
this illness loses many of the skills he or
she has developed. In addition to the loss
of social and language skills, a child with
disintegrative disorder may lose control of
other functions, including bowel and
bladder control.
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Autism Diagnosis (DSM IV)
Impaired social interaction (at least two):
� Markedly deficient regulation of social interaction through multiple nonverbal behaviors, such as eye contact, facial expression, body posture, and gestures
� Lack of peer relationships that are appropriate to developmental level
� Absence of seeking to share achievements, interests, or pleasure with others
� Absence of social or emotional reciprocity
Autism Diagnosis (DSM IV)
Impaired communication (at least one):
� Delayed or absent development of spoken language, for which the patient doesn't try to compensate with gestures
� In patients who can speak, notable deficiency in ability to begin or sustain a conversation
� Language that is repetitive, stereotyped, or idiosyncratic
� Appropriate to developmental stage, absence of social imitative play or spontaneous, make-believe play
Autism Diagnosis (DSM IV)
Activities, behaviors, and interests that are repetitive, restricted, and stereotyped (at least one):
� Abnormal (in focus or intensity) preoccupation with interests that are restricted and stereotyped (such as spinning things)
� Rigid performance of routines or rituals that don't appear to have a function
� Repetitive, stereotyped motor mannerisms (such as hand flapping)
� Persistent absorption with parts of objects
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Autism Diagnosis (DSM IV)
Before age three, the patient shows delayed
or abnormal functioning in one or more of
these areas:
� Social interaction
� Language used in social communication
� Imaginative or symbolic play
These symptoms are not better explained by Childhood
Disintegrative Disorder or Rett's Disorder.
Asperger's Diagnosis (DSM
IV)At least two demonstrations of impaired social interaction:
� Markedly deficient regulation of social interaction through multiple non-verbal behaviors, such as eye contact, facial expression, body posture, and gestures.
� Lack of peer relationships that are appropriate to developmental level
� Absence of seeking to share achievements, interests, or pleasure with others
� Absence of social or emotional reciprocity
Asperger's Diagnosis (DSM
IV)At least one demonstration of activities, behavior, and interests that are repetitive, restricted, and stereotyped:
� Abnormal (in focus or intensity) preoccupation with interests that are restricted and stereotyped (such as spinning things)
� Rigid performance of routines or rituals that don't appear to have a function
� Repetitive, stereotyped motor mannerisms (such as hand flapping)
� Persistent absorption with parts of objects
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Asperger's Diagnosis (DSM
IV)� The symptoms cause clinically important impairment
in social, occupational, or personal functioning.
� There is no clinically important general language delay (the child can speak words by age two, phrases by age three).
� There is no clinically important delay in developing cognition, age-appropriate self-help skills, adaptive behavior (except social interaction), and normal curiosity about the environment.
� The patient doesn't fulfill criteria for Schizophrenia or for another specific pervasive developmental disorder.
PDD NOS(DSM IV)
� Pervasive Developmental Disorder Not Otherwise Specified (PDD NOS) for severe, per-vasive developmental disturbances that do not meet criteria for one of the specific disorders described above or for Schizophrenia, SchizotypalPersonality Disorder, or Avoidant Personality Disorder. DSM-IV particularly mentions atypical autism, which is a label used for disturbances that don't meet criteria for Autistic Disorder because of late age of onset, too few symptoms, or atypical symptoms.
Rett's Disorder(DSM IV)
All of the following suggest normal early
development:
� Prenatal and perinatal development
� Psychomotor development, at least until age 5
months
� Head circumference at birth
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Rett's Disorder(DSM IV)
After this apparently normal beginning, all of these occur:
� Head growth slows abnormally between 5 and 48 months.
� Between 5 and 30 months, the child loses already acquired purposeful hand movements and develops stereotyped hand movements, such as hand washing or hand wringing.
� Early in the course, the child loses interest in the social environment. (However, social interaction often develops later.)
� Gait or movements of trunk are poorly coordinated.
� Severe psychomotor retardation and impairment of expressive and receptive language.
Childhood Disintegrative Disorder
(DSM IV)
� At least until age two, the child develops
normally, as shown by age-appropriate
adaptive behavior, play, social relationships,
and both nonverbal and verbal
communication.
Childhood Disintegrative Disorder
(DSM IV)
Before age 10, the child experiences
clinically important loss of previously
learned skills in the following areas (two or
more required):
� Language (expressive or receptive)
� Adaptive behavior or social skills
� Bladder or bowel control
� Play
� Motor skills
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Childhood Disintegrative Disorder
(DSM IV)
The child functions abnormally in two or more
of the following ways:
� Social interaction is characterized by impaired
nonverbal behaviors, peer relationships, or
emotional or social reciprocity.
� Communication is characterized by delayed or
absent spoken language, inability to converse,
language use that is repetitive or stereotyped,
or absence of varied make-believe play.
Childhood Disintegrative Disorder
(DSM IV)
� Activities, behavior, and interests are
repetitive, restricted, and ste-reotyped;
this includes motor mannerisms and
stereotypies.
� These symptoms are not better
explained by Schizophrenia or by
another specific pervasive
developmental disorder.
Diagnosis (Western)
� Autistic disorder, Asperger’s disorder and
PDD NOS are referred to as autism
spectrum disorders (ASD).
� The current gold standard for diagnosing
ASD is based on clinical history and patient
observation performed by trained clinicians
with the use of structured diagnostic tools
such as the Autism Diagnostic Interview –
revised (ADI-R) and the Autism Diagnostic
Observation Schedule (ADOS).
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Treatment (Western Alternative)
� Gluten Free / Casein-Free diet
� Allergies (Mast Cell Activation)
� Enzymatic therapy
� Craniosacral therapy
Chinese Medicine
� In trying to understand Autism Spectrum
Disorder (ASD) in Chinese medical
terms it is Important to look at :
1. Possible etiological factors
2. Physiology of the organs involved
3. Common symptoms
Etiology
� Immunizations – Although there is
still a debate weather
immunizations can be associated
with Autism, from a Chinese
medical perspective it is
important to take into
consideration that they may be
contributing to toxicity
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10
Etiology
�Antibiotics – In certain cases
(when used inappropriately)
can be the cause of Lingering
Pathogenic Influences (LPF)
and their cold nature can
contribute to the formation of
Phlegm
Etiology
�Parasites – parasitic infections
(worms, fungal and viral) are
more common then we think and
they have a strong influence on
both physiological and
psychological functions (Gu
Syndrome)
Etiology
� Digestive disorders – Children with
Autism almost always present with
digestive disturbances. It is interesting
to note that although in main stream
western medicine this link is
controversial in western alternative
therapies it is very much the hallmark.
In Chinese medicine diet is extremely
important in the treatment of autism
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Etiology
�Constitutional predisposition –
The development of this disorder
at young age as well as the fact
that it is a developmental disorder
point to the involvement of Jing.
Thus in order to address autism
the Kidney Jing must be
addressed
Physiology of the organs
involved
� Heart – “ Hthe heart controls all mental
activities of the mind and is responsible
for insight and cognitionH”, “A healthy
Heart and mind will positively influence
our ability to relate to other peopleH”
Giovanni Maciocia, Foundations of
Chinese Medicine. The heart is also in
charge of appropriate behavior and
understanding of social cues
Physiology of the organs
involved
�Spleen – “The Spleen houses the
intellect (Yi)” Giovanni Maciocia,
Foundations of Chinese Medicine.
The “Yi” is responsible for applied
thinking, studying and generating
ideas. It is interesting to see that
Autistic Children often suffer from
digestive disorders.
4/6/2012
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Physiology of the organs involved
�Kidneys - The Kidneys store
essence – control growth and
development – Developmental
issues always involve Kidneys.
The Kidney are also in charge of
the production of marrow that fills
up the brain.
Physiology of the organs involved
�Liver – The Liver Houses the
Hun. The Hun provides for a
sense of direction as well as a
way to sense other peoples
emotions. The Hun and the Shen
work together in the interactions
with other people.
Pathological factors
contributing to Autism
�Phlegm – Is a very common
factor in ASD. Phlegm can be
both the etiological factor as well
as the pathological factor.
Patterns will vary From Phlegm
Damp to Phlegm misting the
mind to Phlegm wind or fire
4/6/2012
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Pathological factors
contributing to Autism
�Heat - Heat can cause hyperactivity
and violent behavior particularly
when combined with phlegm
�Pathogenic factors – may influence
the mind especially when they
become lingering, or the infestation of
parasites
Gu Syndrome
� Black alcamy
� Infestation of a pathogenic influence
� Gu pathogens represent a type of toxin (gu du). This makes reference to their virulent epidemic quality, but also to the only recently corroborated fact that the metabolic byproducts of parasitic organisms have a toxic affect on the body.
� Cause a variety of symptoms
Gu Syndrome
� the authoritative 6th century encyclopedia Beiji Qianjin Yaofang (Thousand Ducat Formulas) explains, "Some of them will cause bloody stools, while others initiate the desire to lay in a dark room; others may bring about bouts of irregular emotions, such as depression that alternates with periods of sudden happiness; others again cause the extremities to feel heavy and ache all over; and then there are myriads of other symptoms H"
4/6/2012
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Disperse Gu toxins (with diaphoretic
herbs) (san du)
� Zi Su Ye (Follum Perillae Frutescentis),
� Bo He (Herba Men-thae),
� Bai Zhi (Radix Angelicae),
� Lian Qlao (Fructus ForsythiaeSuspensae),
� Gao Ben (Rhizoma et Radix LigusticiSinensis),
� Sheng Ma (Rhizoma Cimicifugae)
� Ju Hua (Flos Chrysantherrit Morifolli).
Kill parasites (sha Chong) and expel
demons (qu gui)
� Da Suan (Bulbul Alli Sativi),
� Yu jin (Tuber Curcumae),
� Shen (Radix Sophorae Flavescentis),
� Huai Hua (Flos Sophorae Japonicae Immaturus),
� She Chuang Zi (Fructus Cnidii Monnieri),
� Jin Yin Hua (Flos Lonicerae Japonicae),
� Qing Hao (Herba Arteinislae Apiaceae),
� Shi Chang Pu (Rhizome Acori Graminei),
� Ding Xiang (Flos Caryophylli),
� He Zi (Fructus Terminaliae Chebulae)
� Bing Lang (Semen Arecae Catechu),
Calm the spirit (by nourishing the qi and
yin of the Lung and Heart) (an Shen)
� Huang Jing (Rhizome Polygonati),
� Bai He (Bulbus Lilii),
� Bei Sha Shen (Radix Glehniae Littoralis),
� Xuan Shen (Radix Scrophulariae
Ningpoensis),
� Sheng Di Huang (Radix Rehmanniae
Glutinosae),
� Xi Yang Shen (Radix Panacis Quinque-folli),
� Fu Shen (Poriae Cocos, Sclerotium)
4/6/2012
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Tonify qi and blood (pungent/detoxifying
substances) (bu qixue)
� Dang Gui (Radix Angelicae Sinensis),
� Bai Shao (Radix Pae-oniae Lactiflorae),
� He Shou Wu (Radix Polygoni Multiflori),
� Gan Cao (Radix Glycyrrhizae Uralensis),
� Huang Qi (Radix Astragals)
� Wu Jia Pi (Cortex Acanthopanacis Radicis).
Move qi and blood (with anti parasitic
herbs) (xingqi poju)
� Chuan Xiong (Radix Ligustici Wallichii),
� Chai Hu (Radix Bupleuri),
� E Zhu (Rhizoma Curcumae Zedoariae),
� San Leng (Rhizoma Sparganii),
� Chen Pi (Pericarpium Citri Reticulatae),
� Mu Xiang (Radix Saussureae seu Vladimirae),
� Ze Lan (Herba Lycopi Lucidi)
� San Qi (Radix Notogin-seng).
Common Symptoms
� Sleep disturbances
� Digestive symptoms
� Irregular appetite
� Hypersensitivity to touch, smell and
sound
� Repetitive Behavior
4/6/2012
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Treatment Modalities
� Shoni Shin
� Cutaneous Electro Stimulation
� Acupuncture
� Tiger warmer
� Magnets
� Herbs
� Nutrition
Shoni ShinBachi Bari (Plectrum), Heragata Arrow, Choto, Hoki, Choki,
Kakibari Rake, Solid Copper Yoneyama and Matsuba
(Pineapple)
Cutaneous electro stimulation
4/6/2012
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Cutaneous electro stimulation
Acupuncture
� With children up to 2 years of age we
use non retention technique. Between 2
to 6 years we try to leave the needle for
a few of minutes, 7-12 retain 4-10
minutes and 12 – 18 between 10 and 20
minutes
� I Use Serin reds (40G) 1 inch needles
but I have commonly seen the use of
thicker gauges.
Common Points Used
� Si Shen Zhen (Four Spirits Needles): A.k.a. Si Shen Cong (M-HN-1), the four points located 1.5 inches in front, behind, and to the left and right of Bai Hui (GV 20)
� Ding Shen Zhen (Stabilizing the Spirit Needles): 5 inches above each of Yin Tang (M-HN-3) and Yang Bai (GB 14)
� Nie San Zhen (Temporal Three Needles): 2 inches perpendicularly above the apex of the ear and 1 inch in front and back of that on the same level; three points in total
4/6/2012
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Common Points Used
� Nie Shan San Zhen (Temporal Above
Three Needles): 3
inches perpendicularly above the apex
of the ear and 1 inch in front and back of
that on the same level; three points in
total
Common Points Used
� Nao San Zhen (Brain Three Needles):
Nao Hu (GV 17), both Nao Kong (GB
19)
� Zhi San Zhen (Intelligence Three
Needles): Shen Ting (GV 24), both Ben
Shen (GB 13)
� Xing Shen Zhen (Arousing the Spirit
Needles): Ren Zhong (GV 26), Shao
Shang (LU 11), Yin Bai (Sp 1)
Tiger warmer
4/6/2012
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Magnets� Qi flows in the con-nective tissue energetic
pathways from the bionorth (-) pole to the biosouth (+) pole
� The designation of bionorth (-) and biosouth(+) is based on the earth's geographic North and South Poles. The bionorth (-) side of the magnet will point to the geographic South Pole (the Antarctic) and will attract the north-seeking needle of a compass. The biosouth(+) side of the magnet will be repelled by the north-seeking needle of a compass and will point to the geographic North Pole (the Arctic). It should be noted that this is opposite to the definition used by the National Bureau of Standards (NBS).
Magnets
� Simple tonification of one acupoint: place the biosouth pole of the magnet facing downward on the skin, with the bionorthpole of the magnet facing outward. This would direct Universal Qi to flow into the child and therefore tonifies.
� Simple sedation of one acupoint: place the bionorth pole of the magnet on the skin, with the biosouth pole facing outward. This directs Qi flow away from the body and is therefore dispersing or sedating.
Basic Autism FormulasBasic Autism FormulasBasic Autism FormulasBasic Autism Formulas
Deficiency pattern
• Shi Chang Pu (Rhizoma AcoriGraminei)
• Yuan Zhi (Radix PolygalaeTenuifoliae)
• Tian Zhu Huang (Concretio SiliceaBambusae)
• Qian Shi (Semen Euryales Ferox)
• Long Chi (Dens Draconis)
• Bai Zhu (Rhizoma AtractylodisMacrocephalae)
• Tian Nan Xing (Rhizoma Arisaematis)
• Bei Xie (Rhizoma Dioscoreae)
• Bai Zi Ren (Semen Biotae Orientalis)
• Xi Yang Shen (Radix PanacisQuinquefolii)
• Chuan Xiong (Radix LigusticiWallichii)
Excess pattern
• Shi Chang Pu (Rhizoma AcoriGraminei)
• Yuan Zhi (Radix PolygalaeTenuifoliae)
• Tian Zhu Huang (Concretio SiliceaBambusae)
• Qian Shi (Semen Euryales Ferox)
• Long Chi (Dens Draconis)
• Huang Lian (Rhizoma Coptidis)
• Rou Gui (Cortex Cinnamomi Cassias)
• Suan Zao Ren (Semen ZiziphiSpinosae)
• Hu Po (Succinum)
• Dan Zhu Ye (Herba LopthatheriGracili)
• Yu Jin (Tuber Curcumae)
4/6/2012
20
Autism TreatmentAutism TreatmentAutism TreatmentAutism Treatment
Main PointsMain PointsMain PointsMain Points
HtHtHtHt9999, Ht, Ht, Ht, Ht8888, Ht, Ht, Ht, Ht7777, Ht, Ht, Ht, Ht3333
UBUBUBUB15151515, UB, UB, UB, UB44444444, Du, Du, Du, Du16161616, GB, GB, GB, GB20202020, Du, Du, Du, Du20202020, Du, Du, Du, Du26262626
Eight extra channels, Neck PointsEight extra channels, Neck PointsEight extra channels, Neck PointsEight extra channels, Neck Points
For Sp type For Sp type For Sp type For Sp type use:use:use:use:
Sp3, Sp10
St36
Liver Liver Liver Liver QiQiQiQiConstraintConstraintConstraintConstraint
use:use:use:use:
LivLivLivLiv2222, Liv, Liv, Liv, Liv14141414
UBUBUBUB18181818
Kidney Vacuity Kidney Vacuity Kidney Vacuity Kidney Vacuity –Kid3
UB23
PhlegmPhlegmPhlegmPhlegm
Ht 5, St 40
A 3 year old with PDDNOS
S/S
� Developmental delays with speech
� Hyperactive
� Frequent ear infection and fluid accumulation behind the eardrum
� Urine reflux
� Bowls tend to be soft but on multiple suplements
� Finger vien very dark and reaching the qi gate
4/6/2012
21
Treatment
� Shoni Shin
� TW5, GB41
� SP9
� GB20
� Formula: Xiao Chai Hu Tang based
B 7 year old ASD, ADD,SID
S/S:
� Developmental delays in speech, gross and fine motor skills, social interaction;
� Inability to follow directions; � Inability to remain focused and behave appropriately in a classroom setting.
� Repetitive self-stimulative behaviors.� Narrow Range of Interests,� Very narrow range of diet� Eye contact is very difficult.� Sensory Input can be too much, or not enough.� Low muscle tone.� Echolalia