Upload
duongquynh
View
221
Download
0
Embed Size (px)
Citation preview
Curriculum vitae
PERSONAL INFORMATION Balázs Sarkadi
WORK EXPERIENCE
October 1972–September 2014 Director of Research UnitNational Blood Service (Hungary)
Research in the area of hematology and stem cells
September 2007–Present Research ProfessorSemmelweis University (Hungary)
Conducting research in medical biophysics, mentoring PhD students
September 2011–Present Scientific adviserResearch Center of Hungarian Acad. Sci., Institute of Molecular Pharmacology (Hungary)
Research in the area of stem cells
EDUCATION AND TRAINING
September 1966–September1972
MDSemmelweis University (Hungary)
General medical doctoral degree
August 1976–August 1980 PhDHungarian Acad. Sci. (Hungary)
Ph.D. in Biochemistry
August 1980–August 1986 DScHungarian Acad. Sci.
Doctor of Sciences, Biology
ADDITIONAL INFORMATION
Expertise Cell biology, membrane biology, stem cell research
Publications Publication list of Balazs Sarkadi (https://vm.mtmt.hu/www/index.php)
Total number of publications: 248
Total number of citations: 10 550
Independent citations: 9 176
IF total: 698,085
2013+
Sarankó H, Tordai H, Telbisz A, Ozvegy-Laczka C, Erdős G, Sarkadi B, Hegedűs
T.
Effects of the gout-causing Q141K polymorphism and a CFTR ΔF508 mimicking mutation on the processing and stability of the ABCG2 protein. Biochem Biophys Res Commun. 2013, 437:140-145.
Pomozi V, Le Saux O, Brampton C, Apana A, Iliás A, Szeri F, Martin L, Monostory K, Paku S, Sarkadi B, Szakács G, Váradi A.
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 1 / 36
Curriculum vitae Balázs Sarkadi
ABCC6 is a basolateral plasma membrane protein. Circ Res. 2013 112:148-151.
Várady G., Cserepes J., Németh, A, Szabó E., Sarkadi B.:
Membrane proteins as personalized biomarkers: where we stand and where we are headed. Biomarkers in Medicine, 2013 accepted for publication"
2013
1.Telbisz A, Ozvegy-Laczka C, Hegedus T, Varadi A, Sarkadi B
Effects of the lipid environment, cholesterol and bile acids on the function of purified, reconstituted human ABCG2 protein.
BIOCHEM J 450: (2)387-395 (2013)
IF: 4.897**
Journal Article/Article/Scientific
2.Grabundzija I, Wang J, Sebe A, Erdei Z, Kajdi R, Devaraj A, Steinemann D, Szuhai K, Stein U, Cantz T, Schambach A, Baum C, Izsvak Z, Sarkadi B, Ivics Z
Sleeping Beauty transposon-based system for cellular reprogramming and targeted gene insertion in induced pluripotent stem cells.
NUCLEIC ACIDS RES epub: 1-19 (2013)
IF: 8.026**
Journal Article/Article/Scientific
3.Erdei Z, Sarkadi B, Brozik A, Szebenyi K, Varady G, Mako V, Pentek A, Orban TI, Apati A
Dynamic ABCG2 expression in human embryonic stem cells provides the basis for stress response.
EUR BIOPHYS J 42: (2-3)169-179 (2013)
IF: 2.139**
Journal Article/Article/Scientific
4.Apáti A, Pászty K, Hegedus L, Kolacsek O, Orbán TI, Erdei Z, Szebényi K, Péntek A, Enyedi A, Sarkadi B
Characterization of calcium signals in human embryonic stem cells and in their differentiated offspring by a stably integrated calcium indicator protein
CELL SIGNAL 25: (4)752-759 (2013)
IF: 4.058**
Journal Article/Article/Scientific
2012
5.Telbisz A, Hegedus C, Ozvegy-Laczka C, Goda K, Varady G, Takats Z, Szabo E, Sorrentino BP, Varadi A, Sarkadi B
Antibody binding shift assay for rapid screening of drug interactions with the human ABCG2 multidrug transporter.
EUR J PHARM SCI 45: (1-2)101-109 (2012)
IF: 3.212*
Journal Article/Article/Scientific
Dependent (self-) citations: 2
6.Sarkadi B, Schatten G
Stem Cell Course in the Middle East: Science Diplomacy and International Collaborations During the Arab Spring
STEM CELL REV REP 8: (1)87-90 (2012)
IF: 3.739*
Journal Article/Article/Scientific
7.Kasza I, Varady G, Andrikovics H, Koszarska M, Tordai A, Scheffer GL, Nemeth A, Szakacs G, Sarkadi B
Expression Levels of the ABCG2 Multidrug Transporter in Human Erythrocytes Correspond to Pharmacologically Relevant Genetic Variations.
PLOS ONE 7: (11) (2012)
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 2 / 36
Curriculum vitae Balázs Sarkadi
IF: 4.092*
Journal Article/Article/Scientific
8.Hegedűs C, Truta-Feles K, Antalffy G, Várady G, Német K, Özvegy-Laczka C, Kéri G, Orfi L, Szakács G, Settleman J, Váradi A, Sarkadi B
Interaction of the EGFR inhibitors gefitinib, vandetanib, pelitinib and neratinib with the ABCG2 multidrug transporter: Implications for the emergence and reversal of cancer drug resistance
BIOCHEM PHARMACOL 84: (3)260-267 (2012)
IF: 4.705*
Journal Article/Article/Scientific
Independent citations: 2
9.Hegedus C, Truta-Feles K, Antalffy G, Brozik A, Kasza I, Nemet K, Orban TI, Ozvegy-Laczka C, Varadi A, Sarkadi B
PI3-kinase and mTOR inhibitors differently modulate the function of the ABCG2 multidrug transporter.
BIOCHEM BIOPH RES CO 420: (4)869-874 (2012)
IF: 2.484*
Journal Article/Article/Scientific
Dependent (self-) citations: 1
10.Gyimesi G, Ramachandran S, Kota P, Dokholyan NV, Sarkadi B, Hegedus T
ATP hydrolysis at one of the two sites in ABC transporters initiates transport related conformational transitions (vol 1808, pg 2954, 2011)
BBA-BIOMEMBRANES 1818: (5)1435 (2012)
IF: 3.990*
Journal Article/Article/Scientific
11.Gyimesi G, Borsodi D, Saranko H, Tordai H, Sarkadi B, Hegedus T
ABCMdb: a database for the comparative analysis of protein mutations in ABC transporters, and a potential framework for a general application.
HUM MUTAT 33: (11)1547-1556 (2012)
IF: 5.686*
Journal Article/Article/Scientific
12.de Boussac H, Orban TI, Varady G, Tihanyi B, Bacquet C, Brozik A, Varadi A, Sarkadi B, Aranyi T
Stimulus-induced expression of the ABCG2 multidrug transporter in HepG2 hepatocarcinoma model cells involves the ERK1/2 cascade and alternative promoters.
BIOCHEM BIOPH RES CO 426: (2)172-176 (2012)
IF: 2.484*
Journal Article/Article/Scientific
13.Apati A, Paszty K, Erdei Z, Szebenyi K, Homolya L, Sarkadi B
Calcium signaling in pluripotent stem cells.
MOL CELL ENDOCRINOL 353: (1-2)57-67 (2012)
IF: 4.192*
Journal Article/Article/Scientific
Independent citations: 7 Dependent (self-) citations: 1 All citations: 8
14.Anita Schamberger, Balázs Sarkadi, Orbán Tamás
Human mirtrons can express functional microRNAs simultaneously from both arms in a flanking exon-independent manner
RNA BIOL 9: (9)1177-1185 (2012)
IF: 4.933*
Journal Article/Article/Scientific
2011
15.Varga N, Vereb Z, Rajnavolgyi E, Nemet K, Uher F, Sarkadi B, Apati A
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 3 / 36
Curriculum vitae Balázs Sarkadi
Mesenchymal stem cell like (MSCl) cells generated from human embryonic stem cells support pluripotent cell growth
BIOCHEM BIOPH RES CO 414: (3)474-480 (2011)
IF: 2.484
Journal Article/Article/Scientific
Dependent (self-) citations: 1
16.Varady G, Sarkadi B, Fatyol K
TTRAP is a novel component of the non-canonical TRAF6-TAK1 TGF-beta signaling pathway.
PLOS ONE 6: (9)e25548 (2011)
IF: 4.092
Journal Article/Article/Scientific
17.Tamás I Orbán, Ágota Apáti, Zsuzsanna Izsvák, Zoltán Ivics, Balázs Sarkadi
Use of Transposon-Transposase Systems for Stable Genetic Modification of Embryonic Stem Cells
In: Craig Atwood(ed.)
Methodological advances in the culture, manipulation and utilization of embryonic stem cells for basic and practical applications.
Rijeka: InTech, 2011. pp. 259-274.
(ISBN:978-953-307-197-8) Chapter in Book/Study/Scientific
18.Szebenyi K, Erdei Z, Pentek A, Sebe A, Orban TI, Sarkadi B, Apati A
Human pluripotent stem cells in pharmacological and toxicological screening: new perspectives for personalized medicine
PERS MED 8: (3)347-364 (2011)
IF: 1.528
Journal Article/Survey paper/Scientific
19.Prochazkova J, Kubala L, Kotasova H, Gudernova I, Sramkova Z, Pekarova M, Sarkadi B, Pachernik J
ABC transporters affect the detection of intracellular oxidants by fluorescent probes.
FREE RADIC RES 45: (7)779-787 (2011)
IF: 2.878
Journal Article/Article/Scientific
20.Kolacsek O, Krízsik V, Schamberger A, Erdei A, Apáti Á, Várady G, Mátés L, Izsvák Z, Ivics Z, Sarkadi B, Orbán TI
Reliable transgene-independent method for determining Sleeping Beauty transposon copy numbers
MOB DNA 2: (2011)
Journal Article/Article/Scientific
Independent citations: 1
21.Homolya L, Orban TI, Csanady L, Sarkadi B
Mitoxantrone is expelled by the ABCG2 multidrug transporter directly from the plasma membrane
BBA-BIOMEMBRANES 1808: (1)154-163 (2011)
IF: 3.990
Journal Article/Article/Scientific
Independent citations: 1 Dependent (self-) citations: 2 All citations: 3
22.Gyimesi G, Ramachandran S, Kota P, Dokholyan NV, Sarkadi B, Hegedus T
ATP hydrolysis at one of the two sites in ABC transporters initiates transport related conformational transitions.
BBA-BIOMEMBRANES 1808: (12)2954-2964 (2011)
IF: 3.990
Journal Article/Article/Scientific
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 4 / 36
Curriculum vitae Balázs Sarkadi
Independent citations: 6 Dependent (self-) citations: 2 All citations: 8
23.Fulop K, Jiang Q, Wetering KV, Pomozi V, Szabo PT, Aranyi T, Sarkadi B, Borst P, Uitto J, Varadi A
ABCC6 does not transport vitamin K3-glutathione conjugate from the liver: Relevance to pathomechanisms of pseudoxanthoma elasticum.
BIOCHEM BIOPH RES CO 415: (3)468-471 (2011)
IF: 2.484
Journal Article/Article/Scientific
Independent citations: 2 Dependent (self-) citations: 1 All citations: 3
24.Brozik A, Hegedus C, Erdei Z, Hegedus T, Ozvegy-Laczka C, Szakacs G, Sarkadi B
Tyrosine kinase inhibitors as modulators of ATP binding cassette multidrug transporters: substrates, chemosensitizers or inducers of acquired multidrug resistance?
EXPERT OPIN DRUG MET 7: (5)623-642 (2011)
IF: 3.119
Journal Article/Article/Scientific
Independent citations: 11 Dependent (self-) citations: 9 All citations: 20
2010
25.Schneider CK, Salmikangas P, Jilma B, Flamion B, Todorova LR, Paphitou A, Haunerova I, Maimets T, Trouvin JH, Flory E, Tsiftsoglou A, Sarkadi B, Gudmundsson K, O Donovan M, Migliaccio G, Ancans J, Maciulaitis R, Robert JL, Samuel A, Ovelgonne JH, Hystad M, Fal AM, Lima BS, MoraruAS, Turcani P, Zorec R, Ruiz S, Akerblom L, Narayanan G, Kent A, Bignami F, Dickson JG, Niederwieser D, Figuerola-Santos MA, Reischl IG, Beuneu C, Georgiev R, Vassiliou M, Pychova A, Clausen M, Methuen T, Lucas S, Schussler-Lenz M, Kokkas V, Buzas Z, MacAleenan N, Galli MC, Line A, Gulbinovic J, Berchem G, Fraczek M, Menezes-Ferreira M, Vilceanu N, Hrubisko M, Marinko P, Timon M, Cheng W, Crosbie GA, Meade N, di Paola ML, VandenDriessche T, Ljungman P, D ApoteL, Oliver-Diaz O, Buttel I, Celis P
Challenges with advanced therapy medicinal products and how to meet them.
NAT REV DRUG DISCOV 9: (3)195-201 (2010)
IF: 28.712
Journal Article/Scientific
26.Sarkadi B, Szakacs G
Understanding transport through pharmacological barriers--are we there yet?
NAT REV DRUG DISCOV 9: (11)897-898 (2010)
Journal Article/Comment, Correction/Scientific
Independent citations: 2 Dependent (self-) citations: 1 All citations: 3
27.Sarkadi B, Orban TI, Szakacs G, Varady G, Schamberger A, Erdei Z, Szebenyi K, Homolya L, Apati A
Evaluation of ABCG2 Expression in Human Embryonic Stem Cells: Crossing the Same River Twice?
STEM CELLS 28: (1)174-176 (2010)
IF: 7.871
Journal Article/Article/Scientific
Independent citations: 10 Dependent (self-) citations: 2 All citations: 12
28.Nathwani SM, Butler S, Fayne D, McGovern NN, Sarkadi B, Meegan MJ, Lloyd DG, Campiani G, Lawler M, Williams DC, Zisterer DM
Novel microtubule-targeting agents, pyrrolo-1,5-benzoxazepines, induce apoptosis in multi-drug-resistant cancer cells.
CANCER CHEMOTH PHARM 66: (3)585-596 (2010)
IF: 2.759
Journal Article/Scientific
Dependent (self-) citations: 1
29.Greene LM, Nathwani SM, Bright SA, Fayne D, Croke A, Gagliardi M, McElligott AM, O Connor L, Carr M, Keely NO, O Boyle NM, Carroll P, Sarkadi B, Conneally E, Lloyd DG, Lawler M, Meegan MJ,
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 5 / 36
Curriculum vitae Balázs Sarkadi
Zisterer DM
The vascular targeting agent combretastatin-A4 and a novel cis-Restricted {beta}-Lactam Analogue, CA-432, induce apoptosis in human chronic myeloid leukemia cells and ex vivo patient samples including those displaying multidrug resistance.
J PHARMACOL EXP THER 335: (2)302-313 (2010)
IF: 4.017
Journal Article/Scientific
Independent citations: 1 Dependent (self-) citations: 1 All citations: 2
30.BATHORI GYOERGY [HU], MEHN DORA, AKOS PAL, KRAJCSI PETER, SZENTE LAJOS, FENYVESI EVA, TELBISZ AGNES, SARKADI BALAZS, VARADI ANDRAS, GEDEY SZILVIA, GLAVINAS HRISTOS [HU], KIS EMESE, NAGY TUENDE, NEMETH ATTILA, MOLNAR EVA
CHOLESTEROL LOADED INSECT CELL MEMBRANES AS TEST SYSTEMS FOR ABC TRANSPORTER PROTEINS
Patent ID: US2010021927 (A1)
Year of submission: 2006.
Publication year: 2010
Submitted to: Magyarország
Protection forms/International patent/Scientific
2009
31.Schamberger A, Kasza I, Homolya L, Sarkadi B, Orbán TI
Sleeping Beauty transzpozon alapú génbevitel: GFP-címkézett ABCG2 multidrogtranszporter-variánsok karakterizálása stabil sejtvonalakban
BIOKÉMIA XXXIII. évf.: 38 (2009)
Journal Article/Not subtyped/Scientific
32.Polgar O, Ediriwickrema LS, Robey RW, Sharma A, Hegde RS, Li YF, Xia D, Ward Y, Dean M, Ozvegy-Laczka C, Sarkadi B, Bates SE
Arginine 383 is a crucial residue in abcg2 biogenesis
BBA-BIOMEMBRANES 1788: (7)1434-1443 (2009)
IF: 3.998
Journal Article/Article/Scientific
Independent citations: 1 Dependent (self-) citations: 1 All citations: 2
33.Orbán TI, Apáti Á, Sarkadi B
Új remény a gén- és őssejtterápiában: a transzpozon alapú génbeviteli eljárások
BIOKÉMIA 33: (1)49-58 (2009)
Journal Article/Article/Scientific
34.Orbán TI, Apáti Á, Izsvák ZS, Ivics Z, Sarkadi B
Egyet fizet, kettőt kap: humán embrionális őssejtek cardiomyocyta irányú differenciációja egy kettős arcú promóterrel, Sleeping Beauty transzpozon-alapú génbevitelt követően
BIOKÉMIA 33: (3)3 (2009)
Journal Article/Abstract/Scientific
35.Orbán TI, Apáti Á, Németh A, Varga N, Krízsik V, Schamberger A, Szebényi K, Erdei Z, Várady G, Karászi É, Homolya L, Német K, Gócza E, Miskey C, Mátés L, Ivics Z, Izsvák Z, Sarkadi B
Applying a "double-feature" promoter to identify cardiomyocytes differentiated from human embryonic stem cells following transposon-based gene delivery
STEM CELLS 27: (5)1077-1087 (2009)
IF: 7.747
Journal Article/Article/Scientific
Independent citations: 7 Dependent (self-) citations: 10 All citations: 17
36.Orbán TI, Apáti Á, Németh A, Varga N, Krízsik V, Schamberger A, Várady G, Német K, Izsvák Z, Sarkadi B
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 6 / 36
Curriculum vitae Balázs Sarkadi
Application of a "double-feature" promoter to identify cardiomyocytes differentiated from human embryonic stem cells: American Society of Gene Therapy 12th Annual Meeting Abstracts
MOL THER 17: (Supplement 1)265-266 (2009)
Journal Article/Abstract/Scientific
37.Katona M, Kiss K, Angyal V, Kucsma N, Sarkadi B, Takáts Z, Szakács G
A mass spectrometry based functional assay for the quantitative assessment of ABC transporter activity
RAPID COMMUN MASS SP 23: (21)3372-3376 (2009)
IF: 2.695
Journal Article/Article/Scientific
Independent citations: 2 Dependent (self-) citations: 1 All citations: 3
38.Kasza I, Hegyi Z, Szabo K, Andrikovics H, Német K, Váradi A, Sarkadi B, Homolya L
Model system for the analysis of cell surface expression of human ABCA1.
BMC CELL BIOL 10: 93 (2009)
IF: 2.654
Journal Article/Article/Scientific
Independent citations: 5
39.Hou Y, Li C, Palaniyandi K, Magtibay PM, Homolya L, Sarkadi B, Chang XB
Effects of putative catalytic base mutation E211Q on ABCG2-mediated methotrexate transport
BIOCHEMISTRY-US 48: (38)9122-9131 (2009)
IF: 3.226
Journal Article/Article/Scientific
Independent citations: 2 Dependent (self-) citations: 1 All citations: 3
40.Hegedüs C, Özvegy-Laczka C, Szakács G, Sarkadi B
Interaction of ABC multidrug transporters with anticancer protein kinase inhibitors: substrates and /or inhibitors?
CURR CANCER DRUG TAR 9: (3)252-272 (2009)
IF: 5.129
Journal Article/Article/Scientific
Independent citations: 12 Dependent (self-) citations: 2 All citations: 14
41.Hegedus C, Ozvegy-Laczka C, Apati A, Magocsi M, Nemet K, Orfi L, Keri G, Katona M, Takats Z, Varadi A, Szakacs G, Sarkadi B
Interaction of nilotinib, dasatinib and bosutinib with ABCB1 and ABCG2: implications for altered anti-cancer effects and pharmacological properties.
BR J PHARMACOL 158: (4)1153-1164 (2009)
IF: 5.204
Journal Article/Article/Scientific
Independent citations: 53 Dependent (self-) citations: 4 All citations: 57
42.Hegedus C, Szakacs G, Homolya L, Orban TI, Telbisz A, Jani M, Sarkadi B
Ins and outs of the abcg2 multidrug transporter: an update on in vitro functional assays
ADV DRUG DELIVER REV 61: (1)47-56 (2009)
IF: 11.957
Journal Article/Survey paper/Scientific
Independent citations: 20 Dependent (self-) citations: 3 All citations: 23
43.Apáti Á, Pászty K, Hegedűs L, Orbán TI, Homolya L, Enyedi Á, Sarkadi B
Calcium signaling in beating human embryonic stem cell-derived cardiomyocytes
FASEB J 2009: (2009)
Journal Article/Abstract/Scientific
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 7 / 36
Curriculum vitae Balázs Sarkadi
Independent citations: 1
2008
44.Turk D, Apati A, Varady G, Orban T, Krizik V, Uher F, Sarkadi B, Nemet K
Comparison of various promoters driving gfp expression in hek and human embryonic stem cells, by using lentiviral transduction
HUM GENE THER 19: (10)1189 (2008)
Journal Article/Abstract/Scientific
45.Szakacs G, Varadi A, Ozvegy-Laczka C, Sarkadi B
The role of abc transporters in drug absorption, distribution, metabolism, excretion and toxicity (adme-tox)
DRUG DISCOV TODAY 13: (9-10)379-393 (2008)
IF: 6.618
Journal Article/Survey paper/Scientific
Independent citations: 94 Dependent (self-) citations: 16 All citations: 110
46.Seres L, Cserepes J, Elkind N B, Törőcsik D, Nagy L, Sarkadi B, Homolya L
Functional ABCG1 expression induces apoptosis in macrophages and other cell types
BBA-BIOMEMBRANES 1778: (10)2378-2387 (2008)
IF: 4.180
Journal Article/Article/Scientific
Independent citations: 10 Dependent (self-) citations: 1 All citations: 11
47.Sarkadi B, Ozvegy-Laczka C, Hegedus C
The role of abc transporters in resistance to anticancer tyrosine kinase inhibitors
ANTICANCER RES 28: (5C)584 (2008)
Journal Article/Abstract/Scientific
48.Sarkadi B
Abc multidrug transporters in cancer drug resistance and drug metabolism
CYTOM PART B-CLIN CY 74B: (1)29 (2008)
Journal Article/Abstract/Scientific
49.Ozvegy-Laczka C, Laczko R, Hegedus C, Litman T, Varady G, Goda K, Hegedus T, Dokholyan NV, Nikolay V, Sorrentino BP, Varadi A, Sarkadi B
Interaction with the 5D3 monoclonal antibody is regulated by intramolecular rearrangements but not by covalent dimer formation of the human ABCG2 multidrug transporter
J BIOL CHEM 283: (38)26059-26070 (2008)
IF: 5.520
Journal Article/Article/Scientific
Independent citations: 12 Dependent (self-) citations: 6 All citations: 18
50.Orban TI, Apati A, Nemeth A, Varga N, Krizsik V, Schamberger A, Varady G, Karaszi E, Homolya L, Nemet K, Miskey C, Ivics Z, Izsvak Z, Sarkadi B
Identification of tissues differentiated from human embryonic stem cells using a non-typical promoter behavior
HUM GENE THER 19: (10)1186 (2008)
Journal Article/Abstract/Scientific
51.Orban TI, Seres L, Ozvegy-Laczka C, Elkind NB, Sarkadi B, Homolya L
Combined localization and real-time functional studies using a gfp-tagged abcg2 multidrug transporter
BIOCHEM BIOPH RES CO 367: (3)667-673 (2008)
IF: 2.648
Journal Article/Article/Scientific
Independent citations: 5 Dependent (self-) citations: 6 All citations: 11
52.Cserepes J, Elkind NB, Szentpetery Zs, Sarkadi B, Varadi A, Klein I, Homolya L, Seres L, Ozvegy-
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 8 / 36
Curriculum vitae Balázs Sarkadi
Laczka Cs
Homo and heterodimer proteins of the ABCG family, methods for detection and screening modulators thereof
Patent ID: US2008187935 (A1)
Year of submission: 2005.
Reference number of submission: US20050571754.
Publication year: 2008
Protection forms/International patent/Scientific
53.Apáti Á, Orbán T, Varga N, Németh A, Schamberger A, Krizsik V, Erdélyi-Belle B, Homolya L, Várady G, Padányi R, Karászi É, Kemna EW, Német K, Sarkadi B
High level functional expression of the ABCG2 multidrug transporter in undifferentiated human embryonic stem cells.
BBA-BIOMEMBRANES 1778: (12)2700-2709 (2008)
IF: 4.180
Journal Article/Article/Scientific
Independent citations: 23 Dependent (self-) citations: 7 All citations: 30
2007
54.Vas V, Vrauko K, Regeczy N, Schwab R, Sarkadi B
Characterization of umbilical cord blood hematopoietic stem, progenitor cell subsets and mesenchymal stem cell lines: a hungarian cord blood bank report
BLOOD REV 21: S88-S89 (2007)
Journal Article/Abstract/Scientific
55.Turk D, Varga N, Varady G, Sarkadi B, Uher F, Nemet K, Apati A
A mesenchymal stem cell-like cell line obtained from human embryonic stem cells provides feeder layer for undifferentiated stem cell growth
HUM GENE THER 18: (10)1081 (2007)
Journal Article/Abstract/Scientific
56.Telbisz A, Muller M, Ozvegy-Laczka C, Homolya L, Szente L, Varadi A, Sarkadi B
Membrane cholesterol selectively modulates the activity of the human abcg2 multidrug transporter
BBA-BIOMEMBRANES 1768: (11)2698-2713 (2007)
IF: 3.640
Journal Article/Article/Scientific
Independent citations: 26 Dependent (self-) citations: 12 All citations: 38
57.Schwab R, Micsik T, Szokoloczi O, Schafer E, Tihanyi B, Tihanyi T, Kupcsulik P, Diofalvi K, Mersich T, Besznyak I, Zarand A, Mihalik R, Sarkadi B, Keri G, Pap A, Jakab F, Kopper L, Petak I
Functional evaluation of multidrug resistance transporter activity in surgical samples of solid tumors
ASSAY DRUG DEV TECHN 5: (4)541-550 (2007)
IF: 1.832
Journal Article/Article/Scientific
Independent citations: 1 Dependent (self-) citations: 1 All citations: 2
58.Orban T, Apati A, Varga N, Krizsik V, Schamberger A, Izsvak Z, Nemet K, Sarkadi B
Transposon-mediated gene transfer into human embryonic stem cells
HUM GENE THER 18: (10)1080-1081 (2007)
Journal Article/Abstract/Scientific
59.Fuller MD, Thompson CH, Zhang ZR, Freeman CS, Schay E, Szakács G, Bakos E, Sarkadi B, McMaster D, French RJ, Pohl J, Kubanek J, McCarty NA
State-dependent inhibition of cystic fibrosis transmembrane conductance regulator chloride channels by a novel peptide toxin
J BIOL CHEM 282: (52)37545-37555 (2007)
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 9 / 36
Curriculum vitae Balázs Sarkadi
IF: 5.581
Journal Article/Article/Scientific
Independent citations: 8 Dependent (self-) citations: 3 All citations: 11
60.Feher A, Turk D, Varady G, Orban T, Szakacs G, Sarkadi B, Settleman J, Nemet K
Down-regulation of the abcg2 multidrug transporter by lentiviral shrna expression eliminates gefitinib-induced multidrug resistance in non-small lung carcinoma cells
HUM GENE THER 18: (10)1070 (2007)
Journal Article/Abstract/Scientific
2006
61.Tusnady G E, Sarkadi B, Simon I, Varadi A
Membrane topology of human ABC proteins
FEBS LETT 580: 1017-1022 (2006)
IF: 3.372
Journal Article/Article/Scientific
Independent citations: 31 Dependent (self-) citations: 2 All citations: 33
62.Szatmari I, Vámosi G, Brazda P, Balint LB, Benko S, Széles L, Jeney V, Özvegy-Laczka G, SzántóA, Barta E, Balla J, Sarkadi B, Nagy L
PPARg reguleted ABCG2 expression confers cytoprotection to human dendritic cells
J BIOL CHEM 281: (33)23812-23823 (2006)
IF: 5.808
Journal Article/Article/Scientific
Independent citations: 79 Dependent (self-) citations: 11 All citations: 90
63.Sarkadi B, Homolya L, Szakacs G, Varadi A
Human multidrug resistance ABCB and ABCG transporters: Participation in a chemoimmunity defense system
PHYSIOL REV 86: 1179-1236 (2006)
IF: 31.441
Journal Article/Survey paper/Scientific
Independent citations: 202 Dependent (self-) citations: 25 All citations: 227
64.Sarkadi B, Muller M, Klein I, Szabo K, Homolya L, Varadi A
ABC transporters for membrane lipids
CHEM PHYS LIPIDS 143: (1-2)40-41 (2006)
Journal Article/Abstract/Scientific
65.Polgar O, Ozvegy Laczka C, Robey R W, Morisaki K, Okada M, Tamaki A, Koblos G, Elkind N B, Ward Y, Dean M, Sarkadi B, Bates S E
Mutational studies of G553 in TM5 of ABCG2: A residue potentially involved in dimerization
BIOCHEMISTRY-US 45: 5251-5260 (2006)
IF: 3.633
Journal Article/Article/Scientific
Independent citations: 13 Dependent (self-) citations: 3 All citations: 16
66.Muller M, Klein I, Kopacsi S, Remaley A T, Rajnavolgyi E, Sarkadi B, Varadi A
Co-expression of human ABCG5 and ABCG8 in insect cells generates an androstan stimulated membrane ATPase activity
FEBS LETT 580: (26)6139-6144 (2006)
IF: 3.372
Journal Article/Article/Scientific
Independent citations: 5
67.Homolya L, Elkind NB, Seres L, Cserepes J, Sarkadi B
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 10 / 36
Curriculum vitae Balázs Sarkadi
Apoptotic effect of ABCG1 expression and function
FEBS J 273: (Suppl. 1)322 (2006)
Journal Article/Abstract/Scientific
68.Cervenak J, Andrikovics H, Ozvegy Laczka C, Tordai A, Nemet K, Varadi A, Sarkadi B
The role of the human ABCG2 multidrug transporter and its variants in cancer therapy and toxicology
CANCER LETT 234: 62-72 (2006)
IF: 3.277
Journal Article/Article/Scientific
Independent citations: 18 Dependent (self-) citations: 7 All citations: 25
2005
69.Seres L, Cserepes J, Elkind NB, Sarkadi B, Homolya L
Subcellular localization of the ABCG1 and ABCG4 transporters in mammalian cells
FEBS J 272: (Suppl. 1)209 (2005)
Journal Article/Abstract/Scientific
70.Schwab Richard, Petak Istvan, Sarkadi Balazs, Kopper Laszlo, Keri Gyoergy, Pap Akos, Szakacs Gergely, Homolya Laszlo, Jakab Ferenc, Moldvay Judit, Feher Arnold
Method And Reagent Kit For Evaluation Of Multidrug-Resistance Activity
Patent ID: WO2005116648
Publication year: 2005
Protection forms/International patent/Scientific
71.Reményi J, Hegedus T, Kovács P, Csík G, Sarkadi B, Hudecz F
In vitro antitumor effect and localization of daunomycin-polypeptide conjugate in sensitive and resistant cell lines
FEBS J 272: 528 (2005)
Journal Article/Abstract/Scientific
Dependent (self-) citations: 1
72.Reményi J, Miklán Z S, Csík G, Mezo G, Gaál D, Kovács P, Sarkadi B, Hudecz F
Drug targeting by peptide conjugates
SCI PHARM 73: KL-5 (2005)
Journal Article/Abstract/Scientific
73.Ozvegy Laczka C, Cserepes J, Elkind N B, Sarkadi B
Tyrosine kinase inhibitor resistance in cancer: role of ABC multidrug transporters
DRUG RESIST UPDATE 8: 15-26 (2005)
IF: 6.172
Journal Article/Survey paper/Scientific
Independent citations: 24 Dependent (self-) citations: 3 All citations: 27
74.Ozvegy Laczka C, Varady G, Koblos G, Ujhelly O, Cervenak J, Schuetz JD, Sorrentino BP, Koomen GJ, Varadi A, Nemet K, Sarkadi B
Function-dependent conformational changes of the ABCG2 multidrug transporter modify its interactionwith a monoclonal antibody on the cell surface
J BIOL CHEM 280: 4219-4227 (2005)
IF: 5.854
Journal Article/Article/Scientific
Independent citations: 24 Dependent (self-) citations: 14 All citations: 38
75.Ozvegy Lacka C, Koblos G, Sarkadi B, Varadi A
Single amino acid (482) variants of the ABCG2 multidrug transporter: major differences in transport capacity and substrate recognition
BBA-BIOMEMBRANES 1668: 53-63 (2005)
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 11 / 36
Curriculum vitae Balázs Sarkadi
IF: 4.224
Journal Article/Article/Scientific
Independent citations: 33 Dependent (self-) citations: 9 All citations: 42
76.Morisaki K, Robey R, Özvegy-Laczka C, Honjo Y, Polgár O, Steadman K, Sarkadi B, Bates S
Single nucleotide polymorphisms modify the transporter activity of ABCG2
CANCER CHEMOTH PHARM 56: 161-172 (2005)
IF: 2.235
Journal Article/Article/Scientific
Independent citations: 29 Dependent (self-) citations: 7 All citations: 36
77.Morisaki K, Robey R, Ozvegy Laczka C, Honjo Y, Polgar O, Steadman K, Sarkadi B, Bates S E
Single nucleotide polymorphisms modify the transporter activity of ABCG2
CANCER CHEMOTH PHARM 56: 161-172 (2005)
IF: 2.235
Journal Article/Article/Scientific
Independent citations: 34 Dependent (self-) citations: 12 All citations: 46
78.Jakab K, Gopcsa L, Adam E, Domjan G, Sarkadi B, Paloczi K
Application of flow cytometry immunophenotyping and multidrug resistance assay in B-cell acute lymphoid leukemia and multiple myeloma
NEOPLASMA 52: 36-42 (2005)
IF: 0.731
Journal Article/Article/Scientific
Independent citations: 2
79.Jakab K, Gopcsa L, Adam E, Domjan G, Sarkadi B, Paloczi K
Application of flow cytometry immunophenotyping and multidrug resistance assay in B-cell acute lymphoid leukemia and multiple myeloma
NEOPLASMA 52: 36-42 (2005)
IF: 0.731
Journal Article/Article/Scientific
Independent citations: 1
80.Elkind N B, Szentpetery Z, Apati A, Ozvegy-Laczka C, Varady G, Ujhelly O, Szabo K, Homolya L, Varadi A, Buday L, Keri G, Nemet K, Sarkadi B
Multidrug transporter ABCG2 prevents tumor cell death induced by the epidermal growth factor receptor inhibitor Iressa (ZD1839, Gefitinib).
CANCER RES 65: (5)1770-1777 (2005)
IF: 7.616
Journal Article/Article/Scientific
Independent citations: 133 Dependent (self-) citations: 18 All citations: 151
2004
81.SZENTPÉTERY ZS, SARKADI B, BAKOS É, VÁRADI A
Functional studies ont he MRP1 multidrug transporter: Characterization of ABC-signature mutant variants
ANTICANCER RES 24: 449-456 (2004)
Journal Article/Conference paper in journal/Scientific
Independent citations: 6 Dependent (self-) citations: 1 All citations: 7
82.Szentpetery Z, Kern A, Liliom K, Sarkadi B, Varadi A
The role of the conserved glycines of ATP-binding cassette signature motifs of MRP1 in the communication between the substrate-binding site and the catalytic centers
J BIOL CHEM 279: 41670-41678 (2004)
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 12 / 36
Curriculum vitae Balázs Sarkadi
IF: 6.355
Journal Article/Article/Scientific
Independent citations: 17 Dependent (self-) citations: 2 All citations: 19
83.Sarkadi B, Ozvegy Laczka C, Nemet K, Varadi A
ABCG2 - a transporter for all seasons
FEBS LETT 567: 116-120 (2004)
Journal Article/Conference paper in journal/Scientific
Independent citations: 146 Dependent (self-) citations: 11 All citations: 157
84.R Schwab, I Peták, Gy Kéri, Á Pap, B Sarkadi, I Kopper, B B Németh, T Micsik, K Diófalvy, G Szakács, J Moldvay, I Homolya
Method and Reagent Kit for Evaluation of Multidrug-Resistance Activity
Patent ID: HU098565
Publication year: 2004
Protection forms/Hungarian patent/Scientific
85.Ozvegy-Laczka C, Hegedus T, Varady G, Ujhelly O, Schuetz JD, Varadi A, Keri G, Orfi L, Nemet K,Sarkadi B
High-affinity interaction of tyrosine kinase inhibitors with the ABCG2
multidrug transporter
MOL PHARMACOL 65: (6)1485-1495 (2004)
IF: 5.080
Journal Article/Article/Scientific
Independent citations: 162 Dependent (self-) citations: 19 All citations: 181
86.Krishnamurthy P, Ross D D, Nakanishi T, Bailey Dell K, Zhou S, Mercer K E, Sarkadi B, Sorrentino B P, Schuetz J D
The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme
J BIOL CHEM 279: 24218-24225 (2004)
IF: 6.355
Journal Article/Article/Scientific
Independent citations: 168 Dependent (self-) citations: 20 All citations: 188
87.KERN A, SZENTPÉTERY Z, LILIOM K, BAKOS É, SARKADI B, VÁRADI A
Nucleotide and transported substrates modulate different steps of the ATPase catalytic cycle of MRP1multidrug transporter
BIOCHEM J 380: 549-560 (2004)
IF: 4.278
Journal Article/Article/Scientific
Independent citations: 2 Dependent (self-) citations: 2 All citations: 4
88.Homolya L, Sarkadi B, Evers R
Simple quantitative fluorescent assay method for determining the activity of transport proteins of interest
Patent ID: US2004033508 (A1)
Year of submission: 2003.
Reference number of submission: US20030312857.
Publication year: 2004
Protection forms/International patent/Scientific
89.GLAVINAS H, KRAJCSI P, CSEREPES J, SARKADI B
The role of ABC transporters in drug resistance, metabolism and toxicity
CURR DRUG DELIV 1: 27-42 (2004)
Journal Article/Article/Scientific
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 13 / 36
Curriculum vitae Balázs Sarkadi
90.CSEREPES J, SZENTPÉTERY Z, SERES L, ÖZVEGY-LACZKA C, LANGMANN T, SCHMITZ G, GLAVINAS H, KLEIN I, HOMOLYA L, VÁRADI A, SARKADI B, ELKIND NB
Functional expression and characterization of the human ABCG1 and ABCG4 proteins: indications forheterodimerization
BIOCHEM BIOPH RES CO 320: 860-867 (2004)
IF: 2.904
Journal Article/Article/Scientific
Independent citations: 43 Dependent (self-) citations: 6 All citations: 49
91.Chu X Y, Huskey S E W, Braun M P, Sarkadi B, Evans D C, Evers R
Transport of ethinylestradiol glucuronide and ethinylestradiol sulfate by the multidrug resistance proteins MRP1, MRP2, and MRP3
J PHARMACOL EXP THER 309: 156-164 (2004)
IF: 4.335
Journal Article/Article/Scientific
Independent citations: 42 Dependent (self-) citations: 1 All citations: 43
92.Chu X, Huskey SE, Braun MP, Sarkadi B, Evans DC, Evers R
Transport of ethinylestradiol glucuronide and ethinylestradiol sulfate by the multidrug resistance proteins MRP1, MRP2, and MRP3.
J PHARMACOL EXP THER 309: 156-164 (2004)
IF: 4.335
Journal Article/Article/Scientific
Independent citations: 35 Dependent (self-) citations: 1 All citations: 36
2003
93.Váradi A, Tusnády GE, Sarkadi B
Membrane topology of ABC transporters
In: Holland IB(ed.)
ABC Proteins: From Bacteria to Man.
Elsevier, 2003.
Chapter in Book/Study/Scientific
Independent citations: 1 Dependent (self-) citations: 1 All citations: 2
94.Ujhelly O, Özvegy C, Várady G, Cervenak J, Homolya L, Grez M, Scheffer G, Roos D, Bates SE, Váradi A, Sarkadi B, Német K
Application of a human multidrug transporter (ABCG2) variant as selectable marker in gene transfer toprogenitor cells
HUM GENE THER 14: 403-412 (2003)
IF: 4.965
Journal Article/Article/Scientific
Independent citations: 15 Dependent (self-) citations: 11 All citations: 26
95.Szakács G, Sarkadi B
Multidrug resistance in cancer and modulation of drug effects by ABC transporters
In: Keri Gy, Toth I(ed.)
Molecular pathomechanisms and new trends in drug research.
London; New York: CRC Press - Taylor and Frances Group, 2003.
(ISBN:0415277256 ; 9780415277259) Chapter in Book/Study/Scientific
96.Sinkó E, Ilias A, Ujhelly O, Homolya L, Scheffer GL, Bergen AA, Sarkadi B, Váradi A
Subcellular localization and N-glycosylation of human ABCC6, expressed in MDCKII cells
BIOCHEM BIOPH RES CO 308: 263-269 (2003)
IF: 2.836
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 14 / 36
Curriculum vitae Balázs Sarkadi
Journal Article/Article/Scientific
Independent citations: 12 Dependent (self-) citations: 4 All citations: 16
97.Hudecz F, Reményi J, Szabó R, Hegedűs T, Sarkadi B, Gaál D
Peptide targeting of daunomycin into sensitive and multidrug resistant tumors
BIOPOLYMERS 71: 299 (2003)
Journal Article/Abstract/Scientific
98.Hudecz F, Kóczán Gy, Reményi J, Hegedűs T, Sarkadi B
Modulation of bioactivity of drugs (daunomycin and methotrexate) by peptide targeting.
In: Cordopatis PA, Manessi-Zoupa E, Paira GN(ed.)
3rd Hellenic Forum on Bioactive Peptides.
Patras: Typorama, 2003. pp. 93-102.
(ISBN:960-762029-1) Chapter in Book/Conference paper/Scientific
99.Homolya L, Váradi A, Sarkadi B
Multidrug resistance-associated proteins: Export pumps for conjugates with glutathione, glucuronate or sulfate
BIOFACTORS 17: 103-114 (2003)
IF: 1.852
Journal Article/Article/Scientific
Independent citations: 80
100.Hegedűs T, Sessler T, Scott R, Thelin W, Bakos E, Váradi A, Szabó K, Homolya L, Milgram SL, Sarkadi B
C-terminal phosphorylation of MRP2 modulates its interaction with PDZ proteins
BIOCHEM BIOPH RES CO 302: 454-461 (2003)
IF: 2.836
Journal Article/Article/Scientific
Independent citations: 51 Dependent (self-) citations: 1 All citations: 52
101.Bodó A, Bakos E, Szeri F, Váradi A, Sarkadi B
The role of multidrug transporters in drug availability, metabolism and toxicity
TOXICOL LETT 140-141: 133-143 (2003)
IF: 2.224
Journal Article/Article/Scientific
Independent citations: 139 Dependent (self-) citations: 2 All citations: 141
102.Bodó A, Bakos E, Szeri F, Váradi A, Sarkadi B
Differential modulation of the human liver conjugate transporters MRP2 and MRP3 by bile acids and organic anions
J BIOL CHEM 278: 23529-23537 (2003)
IF: 6.482
Journal Article/Article/Scientific
Independent citations: 88 Dependent (self-) citations: 8 All citations: 96
2002
103.Varadi A, Szakacs G, Bakos E, Sarkadi B
P glycoprotein and the mechanism of multidrug resistance
In: Bock G, Goode JA(ed.)
Mechanisms of Drug Resistance in Epilepsy: Lessons from Oncology : Symposium on Mechanisms of drug resistance in epilepsy: lessons from oncology, held at the Novartis Foundation, London, 13-15 March 2001.
Chichester: Wiley-Interscience Publication, 2002. pp. 54-68.
(Novartis Foundation Symposia; 243.)
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 15 / 36
Curriculum vitae Balázs Sarkadi
(ISBN:9780470841464) Chapter in Book/Conference paper/Scientific
Independent citations: 19 Dependent (self-) citations: 1 All citations: 20
104.Váradi A, Tusnády G E, Sarkadi B
Membrane topology of the human ABC transporters
In: Cole S, Kuchlerk, Higgins C F(ed.)
ABC Proteins:From Bacteria to Man.
Amsterdam: Kluwer Academic Publishers, 2002. pp. 37-47.
(ISBN:0-12-352551-9) Chapter in Book/Study/Scientific
105.Seprodi Janos (Hu), Sarkadi Balazs (Hu), Hegedus Tamas (Hu), Keri Gyoergy (Hu), Orfi Laszlo (Hu), Idei Miklos (Hu), Hollosy Ferenc (Hu), Teplan Istvan (Hu), Okada Yoshio (Jp)
Soluble Compounds For The Inhibition Of Multidrug Resistance And Pharmaceutical Compositions Thereof
Patent ID: WO0220527
Publication year: 2002
Protection forms/International patent/Scientific
106.Seprodi Janos (Hu), Sarkadi Balazs (Hu), Hegedus Tamas (Hu), Keri Gyoergy (Hu), Orfi Laszlo (Hu), Idei Miklos (Hu), Hollosy Ferenc (Hu), Teplan Istvan (Hu), Okada Yoshio (Jp)
Soluble Compounds For The Inhibition Of Multidrug Resistance And Pharmaceutical Compositions Thereof
Patent ID: AU8613101
Publication year: 2002
Protection forms/Patent in other country/Scientific
107.Özvegy C, Váradi A, Sarkadi B
Characterization of drug transport, ATP hydrolysis, and nucleotide trapping by the human ABCG2 multidrug transporter. Modulation of substrate specificity by a point mutation
J BIOL CHEM 277: 47980-47990 (2002)
IF: 6.696
Journal Article/Article/Scientific
Independent citations: 110 Dependent (self-) citations: 25 All citations: 135
108.Gy Kéri, L Orfi, Gy Bökönyi, T Hegedus, B Hegymegi-Barakonyi, A Ullrich, B Sarkadi
Development of focused tyrosine kinase inhibitory library and testing against MDR
In: Benedetti E, Pedone C(ed.)
Peptides 2002: proceedings of the twenty- seventh European Peptide symposium : August 31-September 6, 2002, Sorrento, Italy.
Napoli: Edizioni Ziino, 2002. pp. 530-531.
(ISBN:8890094818) Chapter in Book/Conference paper/Scientific
109.Ilias A, Urbán Z, Seidl TL, Le Saux O, Sinkó E, Boyd CD, Sarkadi B, Váradi A
Loss of ATP-dependent transport activity in pseudoxanthoma elasticum-associated mutants of humanABCC6 (MRP6)
J BIOL CHEM 277: 16860-16867 (2002)
IF: 6.696
Journal Article/Article/Scientific
Independent citations: 129 Dependent (self-) citations: 19 All citations: 148
110.Homolya L, Varadi A, Sarkadi B
Multidrug Resistance-Associated Proteins: Export Pumps for Conjugates with Glutathione,Glucuronate or Sulfate
In: Pompella A, Banhegyi G, Wellman Rousseau M(ed.)
Thiol metabolism and redox regulation of cellular functions: Proceedings of the NATO Advanced Research Workshop on Thiol Metabolism and Redox Regulation of Cellular Functions, 10-13 April 2002, Pisa, Italy.
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 16 / 36
Curriculum vitae Balázs Sarkadi
Amsterdam: IOS Press, 2002. pp. 107-118.
(NATO Science Series I: Life and Behavioural Science; 347.)
(ISBN:1 58603 282 8) Chapter in Book/Conference paper/Scientific
111.Hegedus T, Orfi L, Seprodi A, Varadi A, Sarkadi B, Keri G
Interaction of tyrosine kinase inhibitors with the human multidrug transporter proteins, MDR1 and MRP1.
BBA-MOL BASIS DIS 1587: (2-3)318-325 (2002)
IF: 3.300
Journal Article/Article/Scientific
Independent citations: 111 Dependent (self-) citations: 5 All citations: 116
2001
112.Szakács G, Özvegy C, Bakos E, Sarkadi B, Váradi A
Role of glycine-534 and glycine-1179 of human multidrug resistance protein (MDR1) in drug-mediatedcontrol of ATP hydrolysis
BIOCHEM J 356: 71-75 (2001)
IF: 4.326
Journal Article/Article/Scientific
Independent citations: 23 Dependent (self-) citations: 10 All citations: 33
113.Szakács G, Langmann T, Özvegy C, Orsó E, Schmitz G, Váradi A, Sarkadi B
Characterization of the ATPase cycle of human ABCA1: implications for its function as a regulator rather than an active transporter
BIOCHEM BIOPH RES CO 288: (5)1258-1264 (2001)
IF: 2.946
Journal Article/Article/Scientific
Independent citations: 34 Dependent (self-) citations: 7 All citations: 41
114.Seprődi J, Hollosy M, Idei M, Kéri Gy, Teplán I, Füzesi M, Hegedűs T, Sarkadi B
Peptides 2000: Synthesis, analysis and biologicak studies of highly hydrophobic but highly soluble peptidomimetics against MDR
In: Martinez J, Fehrentz JA(ed.)
Peptides 2000: Proceedings of the 26th European Peptide Symposium.
Paris: EDK, Paris, France, 2001. pp. 847-848.
(ISBN:9782842540487) Chapter in Book/Conference paper/Scientific
115.Sarkadi B, Homolya L, Holló Zs
Assay and reagent kit for evaluation of multi-drug resistance in cells
Patent ID: US6277655 (B1), US2001019846 (A1)
Year of submission: 1998.
Reference number of submission: US19980203553, US20010840791.
Publication year: 2001
Protection forms/International patent/Scientific
116.Reményi J, Hegedűs T, Sarkadi B, Hudecz F
Effect of a daunomycin-polypeptide conjugate in multidrug resistant tumor cell lines
In: Martinez J, Fehrentz JA(ed.)
Peptides 2000: Proceedings of the 26th European Peptide Symposium.
Paris: EDK, Paris, France, 2001. pp. 941-942.
(ISBN:9782842540487) Chapter in Book/Conference paper/Scientific
117.Reményi J, Hegedűs T, Sarkadi B, Tóth S, Falus A, Gaál D, Hudecz F
Daunomycin-polypetide conjugates: in vitro antitumour effect in sensitive and multidrug resistant cell lines
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 17 / 36
Curriculum vitae Balázs Sarkadi
EUR J CANCER 37: 66 (2001)
Journal Article/Abstract/Scientific
118.Özvegy C, Litman T, Szakács G, Nagy Z, Bates S, Váradi A, Sarkadi B
Functional characterization of the human multidrug transporter, ABCG2, expressed in insect cells
BIOCHEM BIOPH RES CO 285: 111-117 (2001)
IF: 2.946
Journal Article/Article/Scientific
Independent citations: 140 Dependent (self-) citations: 39 All citations: 179
119.Karaszi E, Jakab K, Homolya L, Szakács G, Holló Z, Telek B, Kiss A, Rejtő L, Nahajevszky S, Sarkadi B, Kappelmayer J
Calcein assay for multidrug resistance reliably predicts therapy response and survival rate in acute myeloid leukaemia
BRIT J HAEMATOL 112: 308-314 (2001)
IF: 2.815
Journal Article/Article/Scientific
Independent citations: 35 Dependent (self-) citations: 10 All citations: 45
120.Homolya L, Sarkadi B, Boucher RC
The role of CFTR in the mechanically induced intercellular calcium waves in human airway epithelia
PEDIATR PULM 32: (S22)S239 (2001)
Journal Article/Abstract/Scientific
121.Connolly L, Moran E, Larkin A, Scheffer G, Scheper R, Sarkadi B, Kool M, Clynes M
A new monoclonal antibody, P2A8(6), that specifically recognizes a novel epitope on the multidrug resistance-associated protein 1 (MRP1), but not on MRP2 nor MRP3
HYBRIDOMA HYBRIDOM 20: 333-341 (2001)
Journal Article/Article/Scientific
Independent citations: 3 Dependent (self-) citations: 2 All citations: 5
2000
122.Szakács G, Özvegy C, Bakos E, Sarkadi B, Váradi A
Transition-state formation in ATPase-negative mutants of human MDR1 protein
BIOCHEM BIOPH RES CO 276: 1314-1319 (2000)
IF: 3.055
Journal Article/Article/Scientific
Independent citations: 18 Dependent (self-) citations: 2 All citations: 20
123.Szakacs G, Homolya L, Sarkadi B
Selective and quantitative detection of P-glycoprotein (MDR1) and multidrug resistance protein (MRP1) function in calcein accumulation assay
CYTOMETRY 42: (2)155 (2000)
Journal Article/Abstract/Scientific
124.Smith AJ, van Helvoort A, Van Meer G, Szabó K, Welker E, Szakacs G, Varadi A, Sarkadi B, Borst P
MDR3P-glycoprotein a phosphatidylcholine translocase, transports several cytotoxic drugs and directly interacts with drugs as judged by interference with nucleotide trapping
J BIOL CHEM 275: (31)23530-23539 (2000)
IF: 7.368
Journal Article/Article/Scientific
Independent citations: 142 Dependent (self-) citations: 7 All citations: 149
125.Sarkadi B, Seprodi J, Hegedüs T, Kéri Gy, Orfi L, Idei M, Hollósy F, Teplán I, Okada Y
Multi-Drug Rezisztencia Megszüntetésére Alkalmas Oldékony Vegyületek, E Vegyületeket TartalmazóGyógyászati Készítmények És Eljárás A Vegyületek Eloállítására
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 18 / 36
Curriculum vitae Balázs Sarkadi
Patent ID: P0003554
Publication year: 2000
Protection forms/Hungarian patent/Scientific
126.Reményi J, Hegedűs T, Sarkadi B, Hudecz F
Effect of a daunomycin-polypeptide conjugate in multidrug resistant
J PEPT SCI 6: 218 (2000)
Journal Article/Abstract/Scientific
127.Nagy H, Goda K, Szakacs G, Arceci R, Varadi A, Sarkadi B, Mechetner E, Szabo G
Fluorescence resonance energy transfer studies of function-related changes in the oligomerization and conformational state of Pgp
CYTOMETRY 42: (2)151-152 (2000)
Journal Article/Abstract/Scientific
128.Kern A, Felföldi F, Sarkadi B, Váradi A
Expression and characterization of the N- and C-terminal ATP-binding domains of MRP1
BIOCHEM BIOPH RES CO 273: 913-919 (2000)
IF: 3.055
Journal Article/Article/Scientific
Independent citations: 11
129.Bakos E, Evers R, Sinkó E, Váradi A, Borst P, Sarkadi B
Interactions of the human multidrug resistance proteins MRP1 and MRP2 with organic anions
MOL PHARMACOL 57: 760-768 (2000)
IF: 5.678
Journal Article/Article/Scientific
Independent citations: 189 Dependent (self-) citations: 27 All citations: 216
130.Bakos E, Evers R, Calenda G, Tusnady GE, Szakács G, Varadi A, Sarkadi B
Characterization of the amino-terminal regions in the human multidrug resistance protein (MRP1)
J CELL SCI 113: (Pt 24)4451-4461 (2000)
IF: 5.996
Journal Article/Article/Scientific
Independent citations: 70 Dependent (self-) citations: 6 All citations: 76
1999
131.Vadász ZS, Szabó K, Sarkadi B, Teplán I, Mék M, Idei M, Győrffy E, Seprődi J
New hydrophobic peptide like compounds modulating MDR1-ATPase activity.
In: Bajusz S, Hudecz F(ed.)
Peptides 1998: Proceedings of the 25th European Peptide Symposium. August 30-September 4, 1998, Budapest, Hungary.
Budapest: Akadémiai Kiadó, 1999. p. 640.
(ISBN:9789630576222) Chapter in Book/Scientific
Independent citations: 1
132.Szabó K, Szakács G, Hegedűs T, Sarkadi B
Nucleotide occlusion in the human cystic fibrosis transmembrane conductance regulator. Different patterns in the two nucleotide binding domains
J BIOL CHEM 274: 12209-12212 (1999)
IF: 7.666
Journal Article/Article/Scientific
Independent citations: 65 Dependent (self-) citations: 2 All citations: 67
133.Sharom FJ, Yu X, Lu P, Liu R, Chu JW, Szabó K, Müller M, Hose CD, Monks A, Váradi A, Seprődi J, Sarkadi B
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 19 / 36
Curriculum vitae Balázs Sarkadi
Interaction of the P-glycoprotein multidrug transporter (MDR1) with high affinity peptide chemosensitizers in isolated membranes, reconstituted systems, and intact cells
BIOCHEM PHARMACOL 58: 571-586 (1999)
IF: 2.755
Journal Article/Article/Scientific
Independent citations: 64 Dependent (self-) citations: 10 All citations: 74
134.Sarkadi B, Homolya L, Holló Zs
Assay for multi-drug resistance
Patent ID: US5872014 (A)
Year of submission: 1997.
Reference number of submission: US19970928528.
Publication year: 1999
Submitted to: Magyarország
Protection forms/International patent/Scientific
135.Klein I, Sarkadi B, Váradi A
An inventory of the human ABC proteins
BIOCHIM BIOPHYS ACTA 1461: 237-262 (1999)
IF: 2.590
Journal Article/Survey paper/Scientific
Independent citations: 404 Dependent (self-) citations: 8 All citations: 412
136.Ito S, Woodland C, Sarkadi B, Hockmann G, Walker SE, Koren G
Modeling of P-glycoprotein-involved epithelial drug transport in MDCK cells
AM J PHYSIOL-RENAL 277: F84-F96 (1999)
IF: 3.590
Journal Article/Article/Scientific
Independent citations: 21 Dependent (self-) citations: 4 All citations: 25
1998
137.Váradi A, Tusnády G E, Bakos É, Sarkadi B
Membrane topology of the human multidrug resistance-associated protein (MRP) and its homologs.
In: M Clynes(ed.)
Multiple drug resistance in cancer: molecular, cellular and clinical aspects.
Dordrecht: Kluwer Academic Publishers, 1998. pp. 71-80.
(ISBN:0-7923-5272-6) Chapter in Book/Study/Scientific
138.Varadi A, Tusnady GE, Bakos E, Sarkadi B
Membrane topology of the human multidrug resistance-associated protein (MRP) and its homologs.
CYTOTECHNOLOGY 27: (1-3)71-79 (1998)
IF: 0.616
Journal Article/Article/Scientific
Independent citations: 2
139.Tordai A, Andrikovics H, Kalmar L, Rajczy K, Pénzes M, Sarkadi B, Klein I, Varadi A
High Frequency of the Haemochromatosis C282Y Mutation in Hungary Can Argue Against the Celtic Origin of the Mutation
J MED GENET 35: (10)878-879 (1998)
Journal Article/Comment, Correction/Scientific
Independent citations: 13 Dependent (self-) citations: 2 All citations: 15
140.Szakács G, Jakab K, Antal F, Sarkadi B
Diagnostics of multidrug resistance in cancer
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 20 / 36
Curriculum vitae Balázs Sarkadi
PATHOL ONCOL RES 4: 251-257 (1998)
Journal Article/Article/Scientific
Independent citations: 31 Dependent (self-) citations: 5 All citations: 36
141.Szabo K, Welker E, Bakos E, Muller M, Roninson IB, Varadi A, Sarkadi B
Nucleotide trapping in the human multidrug transporter (MDR1) is stimulated by substrate
FASEB J 12: (4)A441 (1998)
Journal Article/Abstract/Scientific
142.Szabó K, Welker E, Bakos, Müller M, Roninson I, Váradi A, Sarkadi B
Drug-stimulated nucleotide trapping in the human multidrug transporter MDR1. Cooperation of the nucleotide binding domains
J BIOL CHEM 273: (17)10132-10138 (1998)
IF: 7.199
Journal Article/Article/Scientific
Independent citations: 56 Dependent (self-) citations: 16 All citations: 72
143.Szabo K, Muller M, Bakos E, Welker E, Roninson IB, Varadi A, Sarkadi B
Co-operation of the nucleotide binding domains in the human multidrug transporter
FASEB J 12: (8)A1456 (1998)
Journal Article/Abstract/Scientific
144.Holló Z, Homolya L, Hegedűs T, Müller M, Szakács G, Jakab K, Antal F, Sarkadi B
Parallel functional and immunological detection of human multidrug resistance proteins, P-glycoprotein and MRP1
ANTICANCER RES 18: 2981-2987 (1998)
IF: 1.236
Journal Article/Article/Scientific
Independent citations: 18 Dependent (self-) citations: 5 All citations: 23
145.Bakos E, Evers R, Szakács G, Tusnády GE, Welker E, Szabó K, de Haas M, van Deemter L, Borst P, Váradi A, Sarkadi B
Functional multidrug resistance protein (MRP1) lacking the N-terminal transmembrane domain
J BIOL CHEM 273: (48)32167-32175 (1998)
IF: 7.199
Journal Article/Article/Scientific
Independent citations: 211 Dependent (self-) citations: 38 All citations: 249
1997
146.Tusnády GE, Bakos E, Váradi A, Sarkadi B
Membrane topology distinguishes a subfamily of the ATP-binding cassette (ABC) transporters
FEBS LETT 402: (1)1-3 (1997)
IF: 3.504
Journal Article/Article/Scientific
Independent citations: 215 Dependent (self-) citations: 15 All citations: 230
147.Tordai A, Klein I, Rajczy K, Penzes M, Sarkadi B, Varadi A
Prevalence of factor V Leiden (Arg506Gln) in Hungary.
BRIT J HAEMATOL 99: 466-467 (1997)
Journal Article/Comment, Correction/Scientific
Independent citations: 7
148.Szabó K, Bakos E, Welker E, Müller M, Goodfellow HR, Higgins CF, Váradi A, Sarkadi B
Phosphorylation site mutations in the human multidrug transporter modulate its drug-stimulated ATPase activity
J BIOL CHEM 272: 23165-23171 (1997)
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 21 / 36
Curriculum vitae Balázs Sarkadi
IF: 6.963
Journal Article/Article/Scientific
Independent citations: 41 Dependent (self-) citations: 3 All citations: 44
149.Sarkadi B, Müller M
Search for specific inhibitors of multidrug resistance in cancer
SEMIN CANCER BIOL 8: 171-182 (1997)
IF: 4.074
Journal Article/Article/Scientific
Independent citations: 49
150.Bakos E, Klein I, Welker E, Szabó K, Müller M, Sarkadi B, Váradi A
Characterization of the human multidrug resistance protein containing mutations in the ATP-binding cassette signature region
BIOCHEM J 323: 777-783 (1997)
IF: 3.579
Journal Article/Article/Scientific
Independent citations: 38 Dependent (self-) citations: 5 All citations: 43
1996
151.Sarkadi B, Müller M, Holló Z
The multidrug transporters--proteins of an ancient immune system
IMMUNOL LETT 54: 215-219 (1996)
IF: 1.255
Journal Article/Article/Scientific
Independent citations: 14 Dependent (self-) citations: 1 All citations: 15
152.Sarkadi B, Homolya L, Holló Zs
Assay and reagent kit for the quantitative in vitro determination in biological specimens of the activity of proteins causing multi-drug resistance in tumors
Patent ID: CA2198731 (A1), WO9606945 (A1)
Year of submission: 1995.
Reference number of submission: CA19952198731, WO1995HU00042.
Publication year: 1996
Submitted to: Amerikai Egyesült Államok
Protection forms/International patent/Scientific
153.Müller M, Bakos E, Welker E, Váradi A, Germann UA, Gottesman MM, Morse BS, Roninson IB, Sarkadi B
Altered drug-stimulated ATPase activity in mutants of the human multidrug resistance protein
J BIOL CHEM 271: 1877-1883 (1996)
IF: 7.452
Journal Article/Article/Scientific
Independent citations: 88 Dependent (self-) citations: 43 All citations: 131
154.Homolya L, Holló Z, Hegedûs T, Sarkadi B
Quantitative Characterization of P-glycoprotein Function
CELL BIOL INT 20: (3)233 (1996)
Journal Article/Abstract/Scientific
155.Homolya L, Müller M, Holló Zs, Sarkadi B
Fluorescence assay for studying P-glycoprotein function at single cell level
In: J Slavik(ed.)
Fluorescence Microscopy and Fluorescent Probes.
New York: Plenum Press, 1996. pp. 241-245.
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 22 / 36
Curriculum vitae Balázs Sarkadi
(ISBN:0-306-45392-4) Chapter in Book/Study/Scientific
156.Homolya L, Holló M, Müller M, Mechetner EB, Sarkadi B
A new method for a quantitative assessment of P-glycoprotein-related multidrug resistance in tumour cells
BRIT J CANCER 73: 849-855 (1996)
IF: 3.666
Journal Article/Article/Scientific
Independent citations: 49 Dependent (self-) citations: 15 All citations: 64
157.Holló Z, Homolya L, Hegedűs T, Sarkadi B
Transport properties of the multidrug resistance-associated protein (MRP) in human tumour cells
FEBS LETT 383: 99-104 (1996)
IF: 3.750
Journal Article/Article/Scientific
Independent citations: 148 Dependent (self-) citations: 17 All citations: 165
158.Bakos E, Hegedűs T, Holló Z, Welker E, Tusnády GE, Zaman GJ, Flens MJ, Váradi A, Sarkadi B
Membrane topology and glycosylation of the human multidrug resistance-associated protein
J BIOL CHEM 271: (21)12322-12326 (1996)
IF: 7.452
Journal Article/Article/Scientific
Independent citations: 194 Dependent (self-) citations: 34 All citations: 228
1995
159.Welker E, Szabó K, Holló Z, Müller M, Sarkadi B, Váradi A
Drug-stimulated ATPase activity of a deletion mutant of the human multidrug-resistance protein (MDR1)
BIOCHEM BIOPH RES CO 216: 602-609 (1995)
IF: 3.179
Journal Article/Article/Scientific
Independent citations: 13 Dependent (self-) citations: 4 All citations: 17
160.
Sarkadi B
(ed.)
ICRO International Symposium and Course on Membrane Transporters and Channels
Magyarország, Budapest1995.05.22-1995.06.04: 1995.
Conference proceedings/ /Scientific
1994
161.Stutts MJ, Gabriel SE, Price EM, Sarkadi B, Olsen JC, Boucher RC
Pyridine nucleotide redox potential modulates cystic fibrosis transmembrane conductance regulator Cl- conductance
J BIOL CHEM 269: 8667-8674 (1994)
IF: 7.716
Journal Article/Article/Scientific
Independent citations: 13 Dependent (self-) citations: 2 All citations: 15
162.Sarkadi B, Homolya L, Holló Z, Müller M
Quantitative in vitro determination of P-glycoprotein function in tumor cells.
ANTI-CANCER DRUG 5: (1)14 (1994)
Journal Article/Abstract/Scientific
163.Sarkadi B, Müller M, Homolya L, Holló Z, Seprődi J, Germann UA, Gottesman MM, Price EM, Boucher RC
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 23 / 36
Curriculum vitae Balázs Sarkadi
Interaction of bioactive hydrophobic peptides with the human multidrug transporter
FASEB J 8: 766-770 (1994)
IF: 15.115
Journal Article/Article/Scientific
Independent citations: 66 Dependent (self-) citations: 19 All citations: 85
164.Kovács T, Corvazier E, Papp B, Magnier C, Bredoux R, Enyedi A, Sarkadi B, Enouf J
Controlled proteolysis of Ca(2+)-ATPases in human platelet and non-muscle cell membrane vesicles. Evidence for a multi-sarco/endoplasmic reticulum Ca(2+)-ATPase system
J BIOL CHEM 269: 6177-6184 (1994)
IF: 7.716
Journal Article/Article/Scientific
Independent citations: 19 Dependent (self-) citations: 19 All citations: 38
165.Holló Z, Homolya L, Davis CW, Sarkadi B
Calcein accumulation as a fluorometric functional assay of the multidrug transporter.
BRIT J HAEMATOL 87: (1)33 (1994)
Journal Article/Abstract/Scientific
166.Holló Z, Homolya L, Davis CW, Sarkadi B
Calcein accumulation as a fluorometric functional assay of the multidrug transporter
BIOCHIM BIOPHYS ACTA 1191: 384-388 (1994)
IF: 2.507
Journal Article/Article/Scientific
Independent citations: 182 Dependent (self-) citations: 18 All citations: 200
1993
167.Yankaskas Jr, Haizlip JE, Conrad M, Koval D, Lazarowski E, Paradiso AM, Rinehart CA Jr, Sarkadi B, Schlegel R, Boucher RC
Papilloma virus immortalized tracheal epithelial cells retain a well-differentiated phenotype
AM J PHYSIOL 264: C1219-C1230 (1993)
IF: 3.139
Journal Article/Article/Scientific
Independent citations: 103 Dependent (self-) citations: 15 All citations: 118
168.Yankaskas JR, Suchindran H, Sarkadi B, Nettesheim P, Randell SH
CYSTIC-FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (CFTR) PROTEIN IS SELECTIVELY EXPRESSED IN CILIATED AIRWAY EPITHELIAL-CELLS
AM REV RESPIR DIS 147: A26 (1993)
Journal Article/Abstract/Scientific
Independent citations: 3
169.Papp B, Pászty K, Kovács T, Sarkadi B, Gárdos G, Enouf J, Enyedi A
Characterization of the inositol trisphosphate-sensitive and insensitive calcium stores by selective inhibition of the endoplasmic reticulum-type calcium pump isoforms in isolated platelet membrane vesicles
CELL CALCIUM 14: 531-538 (1993)
IF: 4.545
Journal Article/Article/Scientific
Independent citations: 36 Dependent (self-) citations: 19 All citations: 55
170.König T, Kapus A, Sarkadi B
Effects of equisetin on rat liver mitochondria: evidence for inhibition of substrate anion carriers of the inner membrane
J BIOENERG BIOMEMBR 25: 537-545 (1993)
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 24 / 36
Curriculum vitae Balázs Sarkadi
IF: 4.761
Journal Article/Article/Scientific
Independent citations: 11
171.Homolya L, Holló Z, Germann UA, Pastan I, Gottesman MM, Sarkadi B
Fluorescent cellular indicators are extruded by the multidrug resistance protein
J BIOL CHEM 268: 21493-21496 (1993)
IF: 6.793
Journal Article/Article/Scientific
Independent citations: 362 Dependent (self-) citations: 35 All citations: 397
1992
172.Sarkadi B, Price EM, Boucher RC, Germann UA, Scarborough GA
Expression of the human multidrug resistance cDNA in insect cells generates a high activity drug-stimulated membrane ATPase
J BIOL CHEM 267: 4854-4858 (1992)
IF: 6.733
Journal Article/Article/Scientific
Independent citations: 368 Dependent (self-) citations: 60 All citations: 428
173.Sarkadi B, Bauzon D, Huckle WR, Earp HS, Berry A, Suchindran H, Price EM, Olson JC, Boucher RC, Scarborough GA
Biochemical characterization of the cystic fibrosis transmembrane conductance regulator in normal and cystic fibrosis epithelial cells
J BIOL CHEM 267: 2087-2095 (1992)
IF: 6.733
Journal Article/Article/Scientific
Independent citations: 67 Dependent (self-) citations: 27 All citations: 94
174.Papp B, Enyedi A, Pászty K, Kovács T, Sarkadi B, Gárdos G, Magnier C, Wuytack F, Enouf J
Simultaneous presence of two distinct endoplasmic-reticulum-type calcium-pump isoforms in human cells. Characterization by radio-immunoblotting and inhibition by 2,5-di-(t-butyl)-1,4-benzohydroquinone
BIOCHEM J 288: 297-302 (1992)
IF: 3.716
Journal Article/Article/Scientific
Independent citations: 75 Dependent (self-) citations: 39 All citations: 114
175.Olsen JC, Johnson LG, Stutts MJ, Sarkadi B, Yankaskas Jr, Swanstrom R, Boucher RC
Correction of the apical membrane chloride permeability defect in polarized cystic fibrosis airway epithelia following retroviral-mediated gene transfer
HUM GENE THER 3: 253-266 (1992)
IF: 4.950
Journal Article/Article/Scientific
Independent citations: 57 Dependent (self-) citations: 23 All citations: 80
176.Kapui Z, Hermecz I, Sarkadi B, Szentmiklósi P, Tardos L, Blaskó G
Comparative studies of drotaverine--acephyllinate (Depogen) and pentoxifylline (Trental)
THROMB RES 66: 693-706 (1992)
IF: 1.293
Journal Article/Article/Scientific
Independent citations: 3 Dependent (self-) citations: 3 All citations: 6
177.Johnson LG, Olsen JC, Sarkadi B, Moore KL, Swanstrom R, Boucher RC
Efficiency of gene transfer for restoration of normal airway epithelial function in cystic fibrosis
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 25 / 36
Curriculum vitae Balázs Sarkadi
NAT GENET 2: 21-25 (1992)
Journal Article/Article/Scientific
Independent citations: 230 Dependent (self-) citations: 19 All citations: 249
1991
178.Sarkadi B, Tordai A, Homolya L, Scharff O, Gárdos G
Calcium influx and intracellular calcium release in anti-CD3 antibody-stimulated and thapsigargin-treated human T lymphoblasts
J MEMBRANE BIOL 123: 9-21 (1991)
IF: 3.436
Journal Article/Article/Scientific
Independent citations: 38 Dependent (self-) citations: 4 All citations: 42
179.Sarkadi B, Parker JC
Activation of ion transport pathways by changes in cell volume
BIOCHIM BIOPHYS ACTA 1071: 407-427 (1991)
IF: 2.460
Journal Article/Article/Scientific
Independent citations: 276 Dependent (self-) citations: 6 All citations: 282
180.Papp B, Enyedi A, Kovács T, Sarkadi B, Wuytack F, Thastrup O, Gárdos G, Bredoux R, Levy Toledano S, Enouf J
Demonstration of two forms of calcium pumps by thapsigargin inhibition and radioimmunoblotting in platelet membrane vesicles
J BIOL CHEM 266: 14593-14596 (1991)
IF: 6.714
Journal Article/Article/Scientific
Independent citations: 110 Dependent (self-) citations: 36 All citations: 146
1990
181.Sarkadi B, Tordai A, Müller M, Gárdos G
Regulation of stimulus-induced calcium transport pathways in human T (Jurkat) lymphoblasts
MOL IMMUNOL 27: (12)1297-1306 (1990)
IF: 2.000
Journal Article/Article/Scientific
Independent citations: 8 Dependent (self-) citations: 1 All citations: 9
182.Sarkadi B, Tordai A, Gárdos G
Membrane depolarization selectively inhibits receptor-operated calcium channels in human T (Jurkat) lymphoblasts
BIOCHIM BIOPHYS ACTA 1027: (2)130-140 (1990)
IF: 2.411
Journal Article/Article/Scientific
Independent citations: 25 Dependent (self-) citations: 5 All citations: 30
183.Kovács T, Tordai A, Szász I, Sarkadi B, Gárdos G
Membrane depolarization inhibits thrombin-induced calcium influx and aggregation in human platelets
FEBS LETT 266: (1-2)171-174 (1990)
IF: 3.420
Journal Article/Article/Scientific
Independent citations: 7 Dependent (self-) citations: 2 All citations: 9
184.Kapui Z, Hermecz I, Sarkadi B, Szentmiklósi P, Tardos L
Drotaverin-acefillinát (Depogen) és pentoxifilln (Trental) összehasnlító vizsgálata
In: Szabó J Z, Szentmiklósi A J(ed.)
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 26 / 36
Curriculum vitae Balázs Sarkadi
A keringésfarmakológiai kutatások újabb eredményei.
Debrecen: DOTE, 1990. pp. 247-264.
(ISBN:9637286241) Chapter in Book/Study/Scientific
Dependent (self-) citations: 1
1989
185.Tordai A, Sarkadi B, Görög G, Gárdos G
Inhibition of the CD3-mediated calcium signal by protein kinase C activators in human T (Jurkat) lymphoblastoid cells
IMMUNOL LETT 20: (1)47-52 (1989)
IF: 1.509
Journal Article/Article/Scientific
Independent citations: 15 Dependent (self-) citations: 3 All citations: 18
186.Sarkadi B, Gárdos G
Drug actions on potassium fluxes in red cells
In: B U Raess, G Tunnicliff(ed.)
The Red Cell Membrane: A Model For Solute Transport.
New York: Humana Press, 1989. pp. 369-396.
(ISBN:0-89603-158-6) Chapter in Book/Study/Scientific
187.Papp B, Sarkadi B, Enyedi A, Caride AJ, Penniston JT, Gárdos G
Functional domains of the in situ red cell membrane calcium pump revealed by proteolysis and monoclonal antibodies. Possible sites for regulation by calpain and acidic lipids
J BIOL CHEM 264: 4577-4582 (1989)
IF: 6.636
Journal Article/Article/Scientific
Independent citations: 29 Dependent (self-) citations: 14 All citations: 43
188.Magocsi M, Sarkadi B, Kovács T, Gárdos G
Thrombin-induced activation of calcium transport pathways and their role in platelet functions
BIOCHIM BIOPHYS ACTA 984: 88-96 (1989)
IF: 2.261
Journal Article/Article/Scientific
Independent citations: 28 Dependent (self-) citations: 4 All citations: 32
189.Kovács T, Szász I, Sarkadi B, Brezanoczy F, Gárdos G
Volume regulatory mechanisms of human granulocytes in hypoosmotic media
ACTA BIOCHIM BIOPHYS ACAD SCI HUNG 24: 83-99 (1989)
IF: 0.508
Journal Article/Article/Scientific
Independent citations: 4 Dependent (self-) citations: 1 All citations: 5
190.Enouf J, Bredoux R, Bourdeau N, Sarkadi B, Levy Toledano S
Further characterization of the plasma membrane- and intracellular membrane-associated platelet Ca2+ transport systems
BIOCHEM J 263: 547-552 (1989)
IF: 3.631
Journal Article/Article/Scientific
Independent citations: 34 Dependent (self-) citations: 5 All citations: 39
1988
191.Szirmai M, Sarkadi B, Szász I, Gárdos G
Volume regulatory mechanisms of human platelets
HAEMATOLOGIA (BUDAPEST) 21: 33-40 (1988)
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 27 / 36
Curriculum vitae Balázs Sarkadi
IF: 0.127
Journal Article/Article/Scientific
Independent citations: 3 Dependent (self-) citations: 2 All citations: 5
192.Sarkadi B, Enyedi A, Penniston JT, Verma AK, Dux L, Molnár E, Gárdos G
Characterization of membrane calcium pumps by simultaneous immunoblotting and 32P radiography
BIOCHIM BIOPHYS ACTA 939: 40-46 (1988)
IF: 2.278
Journal Article/Article/Scientific
Independent citations: 22 Dependent (self-) citations: 14 All citations: 36
193.Magocsi M, Enyedi A, Sarkadi B, Gárdos G
Effects of phosphoinositides on calcium movements in human platelet membrane vesicles
BIOCHIM BIOPHYS ACTA 944: 202-212 (1988)
IF: 2.278
Journal Article/Article/Scientific
Independent citations: 17 Dependent (self-) citations: 2 All citations: 19
1987
194.Ujhelyi E, Onody K, Minh DQ, Sarkadi B, Fust G
Enhancing effect of alpha-interferon on the C2 synthesis by cultured human monocytes
IMMUNOL LETT 15: 41-44 (1987)
IF: 1.224
Journal Article/Article/Scientific
Independent citations: 1 Dependent (self-) citations: 4 All citations: 5
195.Sarkadi B, Enyedi A, Gárdos G
Conformational changes of the in situ red cell membrane calcium pump affect its proteolysis
BIOCHIM BIOPHYS ACTA 899: 129-133 (1987)
IF: 2.394
Journal Article/Article/Scientific
Independent citations: 7 Dependent (self-) citations: 1 All citations: 8
196.Hunyady L, Sarkadi B, Cragoe EJ Jr, Spät A, Gárdos G
Activation of sodium-proton exchange is not a prerequisite for Ca2+ mobilization and aggregation in human platelets
FEBS LETT 225: 72-76 (1987)
IF: 3.381
Journal Article/Article/Scientific
Independent citations: 18
197.Enyedi A, Flura M, Sarkadi B, Gárdos G, Carafoli E
The maximal velocity and the calcium affinity of the red cell calcium pump may be regulated independently
J BIOL CHEM 262: 6425-6430 (1987)
IF: 6.373
Journal Article/Article/Scientific
Independent citations: 81 Dependent (self-) citations: 23 All citations: 104
1986
198.Sarkadi B, Enyedi A, Földes Papp Z, Gárdos G
Molecular characterization of the in situ red cell membrane calcium pump by limited proteolysis
J BIOL CHEM 261: 9552-9557 (1986)
IF: 6.315
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 28 / 36
Curriculum vitae Balázs Sarkadi
Journal Article/Article/Scientific
Independent citations: 129 Dependent (self-) citations: 18 All citations: 147
199.Enyedi A, Sarkadi B, Földes Papp Z, Monostory S, Gárdos G
Demonstration of two distinct calcium pumps in human platelet membrane vesicles
J BIOL CHEM 261: 9558-9563 (1986)
IF: 6.315
Journal Article/Article/Scientific
Independent citations: 61 Dependent (self-) citations: 9 All citations: 70
1985
200.Sarkadi B, Cheung R, MacK E, Grinstein S, Gelfand EW, Rothstein A
Cation and anion transport pathways in volume regulatory response of human lymphocytes to hyposmotic media
AM J PHYSIOL 248: C480-C487 (1985)
IF: 3.011
Journal Article/Article/Scientific
Independent citations: 78 Dependent (self-) citations: 9 All citations: 87
201.Sarkadi B, Gárdos G
Calcium-induced potassium transport in cell membranes
In: Martonosi M(ed.)
Enzymes of Biological Membranes.
New York: Plenum Press, 1985. pp. 193-234.
Vol. 3., Membrane transport
(ISBN:0306414538) Chapter in Book/Study/Scientific
202.Sarkadi B, Grinstein S, Rothstein A, Gárdos G
Analysis of Ca2+-induced K+-transport of human erythrocytes in propionate media
ACTA BIOCHIM BIOPHYS ACAD SCI HUNG 20: 193-202 (1985)
IF: 0.517
Journal Article/Article/Scientific
Independent citations: 2
1984
203.Sarkadi B, Attisano L, Grinstein S, Buchwald M, Rothstein A
Volume regulation of Chinese hamster ovary cells in anisoosmotic media
BIOCHIM BIOPHYS ACTA 774: 159-168 (1984)
IF: 2.536
Journal Article/Article/Scientific
Independent citations: 57 Dependent (self-) citations: 10 All citations: 67
204.Sarkadi B, MacK E, Rothstein A
Ionic events during the volume response of human peripheral blood lymphocytes to hypotonic media. II. Volume- and time-dependent activation and inactivation of ion transport pathways
J GEN PHYSIOL 83: 513-527 (1984)
IF: 5.306
Journal Article/Article/Scientific
Independent citations: 38 Dependent (self-) citations: 6 All citations: 44
205.Sarkadi B, MacK E, Rothstein A
Ionic events during the volume response of human peripheral blood lymphocytes to hypotonic media. I. Distinctions between volume-activated Cl- and K+ conductance pathways
J GEN PHYSIOL 83: 497-512 (1984)
IF: 5.306
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 29 / 36
Curriculum vitae Balázs Sarkadi
Journal Article/Article/Scientific
Independent citations: 71 Dependent (self-) citations: 6 All citations: 77
206.Grinstein S, Rothstein A, Sarkadi B, Gelfand EW
Responses of lymphocytes to anisotonic media: volume-regulating behavior
AM J PHYSIOL 246: C204-C215 (1984)
IF: 2.905
Journal Article/Article/Scientific
Independent citations: 267 Dependent (self-) citations: 22 All citations: 289
207.Farkas G, Enyedi A, Sarkadi B, Gárdos G, Nagy Z, Faragó A
Cyclic AMP-dependent protein kinase stimulates the phosphorylation of phosphatidylinositol to phosphatidylinositol-4-monophosphate in a plasma membrane preparation from pig granulocytes
BIOCHEM BIOPH RES CO 124: 871-876 (1984)
IF: 3.020
Journal Article/Article/Scientific
Independent citations: 18 Dependent (self-) citations: 1 All citations: 19
208.Enyedi A, Faragó A, Sarkadi B, Gárdos G
Cyclic AMP-dependent protein kinase and Ca2+-calmodulin stimulate the formation of polyphosphoinositides in a sarcoplasmic reticulum preparation of rabbit heart
FEBS LETT 176: 235-238 (1984)
IF: 2.965
Journal Article/Article/Scientific
Independent citations: 20 Dependent (self-) citations: 1 All citations: 21
1983
209.Sarkadi B, Enyedi A, Faragó A, Mészáros G, Kremmer T, Gárdos G
Cyclic AMP-dependent protein kinase stimulates the formation of polyphosphoinositides in lymphocyte plasma membrane
FEBS LETT 152: 195-198 (1983)
IF: 2.879
Journal Article/Article/Scientific
Independent citations: 15 Dependent (self-) citations: 6 All citations: 21
210.Grinstein S, Cohen S, Sarkadi B, Rothstein A
Induction of 86Rb fluxes by Ca2+ and volume changes in thymocytes and their isolated membranes
J CELL PHYSIOL 116: 352-362 (1983)
IF: 2.852
Journal Article/Article/Scientific
Independent citations: 29 Dependent (self-) citations: 7 All citations: 36
211.Enyedi A, Sarkadi B, Faragó A, Szász I, Gárdos G
The effect of cyclic AMP-dependent protein kinase on the formation of polyphosphoinositides in erythrocyte membranes
BIOMED BIOCHIM ACTA 42: S130-S131 (1983)
Journal Article/Article/Scientific
212.Enyedi A, Faragó A, Sarkadi B, Szász I, Gárdos G
Cyclic AMP-dependent protein kinase stimulates the formation of polyphosphoinositides in the plasmamembranes of different blood cells
FEBS LETT 161: 158-162 (1983)
IF: 2.879
Journal Article/Article/Scientific
Independent citations: 35 Dependent (self-) citations: 7 All citations: 42
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 30 / 36
Curriculum vitae Balázs Sarkadi
1982
213.Szász I, Sarkadi B, Gárdos G
Operation of the Ca-dependent K(Rb)-transport in human lymphocytes
HAEMATOLOGIA (BUDAPEST) 15: 83-89 (1982)
Journal Article/Article/Scientific
214.Sarkadi B, Enyedi A, Nyers A, Gárdos G
The function and regulation of the calcium pump in the erythrocyte membrane
ANN NY ACAD SCI 402: 329-348 (1982)
IF: 1.653
Journal Article/Article/Scientific
Independent citations: 37 Dependent (self-) citations: 5 All citations: 42
215.Sarkadi B, Enyedi A, Szász I, Gárdos G
Active calcium transport and calcium-dependent membrane phosphorylation in human peripheral blood lymphocytes
CELL CALCIUM 3: 163-182 (1982)
IF: 2.935
Journal Article/Article/Scientific
Independent citations: 13 Dependent (self-) citations: 6 All citations: 19
216.Enyedi A, Sarkadi B, Gárdos G
On the substrate specificity of the red cell calcium pump
BIOCHIM BIOPHYS ACTA 687: 109-112 (1982)
IF: 2.652
Journal Article/Article/Scientific
Independent citations: 9 Dependent (self-) citations: 1 All citations: 10
217.Enyedi A, Sarkadi B, Nyers A, Gárdos G
Effects of divalent metal ions on the calcium pump and membrane phosphorylation in human red cells
BIOCHIM BIOPHYS ACTA 690: 41-49 (1982)
IF: 2.652
Journal Article/Article/Scientific
Independent citations: 17 Dependent (self-) citations: 3 All citations: 20
1981
218.Szasz I, Sarkadi B, Enyedi A, Gardos G
Ca-transport and CaMg-ATPase activity in human red cell preparations
ACTA BIOL MED GER 40: 429-436 (1981)
IF: 0.569
Journal Article/Article/Scientific
Independent citations: 4
219.Sarkadi B, Enyedi A, Gardos G
METAL-ATP COMPLEXES AS SUBSTRATES AND FREE METAL-IONS AS ACTIVATORS OF THERED-CELL CALCIUM-PUMP
CELL CALCIUM 2: 449-458 (1981)
IF: 1.771
Journal Article/Article/Scientific
Independent citations: 6 Dependent (self-) citations: 2 All citations: 8
220.Sarkadi B, Szász I, Gárdos G
Calcium and calmodulin in the regulation of blood cell functions (a mini-review)
HAEMATOLOGIA (BUDAPEST) 14: 121-136 (1981)
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 31 / 36
Curriculum vitae Balázs Sarkadi
Journal Article/Article/Scientific
221.Marino D, Sarkadi B, Gardos G, Bolis L
CALCIUM-INDUCED ALKALI CATION-TRANSPORT IN NUCLEATED RED-CELLS
MOL PHYSIOL 1: 295-300 (1981)
Journal Article/Article/Scientific
Independent citations: 8 Dependent (self-) citations: 1 All citations: 9
1980
222.Sarkadi B, Enyedi A, Gárdos G
MOLECULAR-PROPERTIES OF THE RED-CELL CALCIUM-PUMP .1. EFFECTS OF CALMODULIN, PROTEOLYTIC DIGESTION AND DRUGS ON THE KINETICS OF ACTIVE CALCIUM-UPTAKE IN INSIDE-OUT RED-CELL MEMBRANE- VESICLES
CELL CALCIUM 1: 287-297 (1980)
Journal Article/Article/Scientific
Independent citations: 93 Dependent (self-) citations: 9 All citations: 102
223.Sarkadi B, Enyedi A, Szász I, Gárdos G
Effect of calmodulin on active calcium uptake and membrane phosphorylation in inside-out red cell membrane vesicles
In: S R Hollán, G Gárdos,
B Sarkadi
(ed.)
Genetics, Structure and Function of Blood Cells: proceedings of the 28th International Congress of Physiological Sciences, Budapest, 1980.
Budapest: Pergamon Press - Akadémiai Kiadó, 1980. pp. 181-188.
(ISBN:9630527324 ; 9780080268187) Chapter in Book/Conference paper/Scientific
224.Sarkadi B, Szász I, Gárdos G
Characteristics and regulation of active calcium transport in inside-out red cell membrane vesicles
BIOCHIM BIOPHYS ACTA 598: 326-338 (1980)
IF: 2.864
Journal Article/Article/Scientific
Independent citations: 100 Dependent (self-) citations: 19 All citations: 119
225.Sarkadi B
Active calcium transport in human red cells
BIOCHIM BIOPHYS ACTA 604: 159-190 (1980)
IF: 2.864
Journal Article/Article/Scientific
Independent citations: 153 Dependent (self-) citations: 5 All citations: 158
226.
S R Hollán, G Gárdos,
B Sarkadi
(ed.)
Genetics, Structure and Function of Blood Cells: proceedings of the 28th International Congress of Physiological Sciences, Budapest, 1980
Budapest: Pergamon Press - Akadémiai Kiadó, 1980. 308p.
(ISBN:9630527324 ; 9780080268187)
Book/Conference proceedings/Scientific
227.Enyedi A, Sarkadi B, Szász I, Bot G, Gárdos G
MOLECULAR-PROPERTIES OF THE RED-CELL CALCIUM-PUMP .2. EFFECTS OF CALMODULIN, PROTEOLYTIC DIGESTION AND DRUGS ON THE CALCIUM- INDUCED MEMBRANE PHOSPHORYLATION BY ATP IN INSIDE-OUT RED-CELL MEMBRANE-VESICLES
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 32 / 36
Curriculum vitae Balázs Sarkadi
CELL CALCIUM 1: 299-310 (1980)
Journal Article/Article/Scientific
Independent citations: 34 Dependent (self-) citations: 8 All citations: 42
1979
228.Sarkadi B, Schubert A, Gárdos G
Effects of calcium-EGTA buffers on active calcium transport in inside-out red cell membrane vesicles
EXPERIENTIA 35: 1045-1047 (1979)
IF: 0.858
Journal Article/Article/Scientific
Independent citations: 42
1978
229.Szász I, Hasitz M, Sarkadi B, Gárdos G
Phosphorylation of the Ca2+ pump intermediate in intact red cells, isolated membranes and inside-outvesicles
MOL CELL BIOCHEM 22: 147-152 (1978)
IF: 1.706
Journal Article/Article/Scientific
Independent citations: 26 Dependent (self-) citations: 7 All citations: 33
230.Szász I, Sarkadi B, Gárdos G
Mechanisms for passive calcium transport in human red cells
ACTA BIOCHIM BIOPHYS ACAD SCI HUNG 13: 239-242 (1978)
IF: 0.421
Journal Article/Article/Scientific
Independent citations: 7
231.Szász I, Sarkadi B, Schubert A, Gárdos G
Effects of lanthanum on calcium-dependent phenomena in human red cells
BIOCHIM BIOPHYS ACTA 512: 331-340 (1978)
IF: 3.215
Journal Article/Article/Scientific
Independent citations: 58 Dependent (self-) citations: 6 All citations: 64
232.Szász I, Sarkadi B, Gárdos G
Effect of drugs on the calcium-dependent rapid potassium transport in calcium-loaded intact red cells
ACTA BIOCHIM BIOPHYS ACAD SCI HUNG 13: 133-141 (1978)
IF: 0.421
Journal Article/Article/Scientific
Independent citations: 8 Dependent (self-) citations: 1 All citations: 9
233.Szász I, Sarkadi B, Gárdos G
Changes in the Ca2+-transport processes of red cells during cold storage in ACD
BRIT J HAEMATOL 39: 559-568 (1978)
IF: 3.196
Journal Article/Article/Scientific
Independent citations: 14 Dependent (self-) citations: 2 All citations: 16
234.Szász I, Hasitz M, Breuer JH, Sarkadi B, Gárdos G
Biconcave shape and its transformations in human red cells
ACTA BIOL ACAD SCI HUNG 29: 1-17 (1978)
IF: 0.163
Journal Article/Article/Scientific
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 33 / 36
Curriculum vitae Balázs Sarkadi
Independent citations: 9
235.Sarkadi B, MacIntyre JD, Gárdos G
Kinetics of active calcium transport in inside-out red cell membrane vesicles
FEBS LETT 89: 78-82 (1978)
IF: 3.004
Journal Article/Article/Scientific
Independent citations: 51 Dependent (self-) citations: 12 All citations: 63
236.Sarkadi B, Alifimoff JK, Gunn RB, Tosteson DC
Kinetics and stoichiometry of Na-dependent Li transport in human red blood cells
J GEN PHYSIOL 72: 249-265 (1978)
IF: 4.855
Journal Article/Article/Scientific
Independent citations: 138 Dependent (self-) citations: 8 All citations: 146
237.Sarkadi B, Tosteson D C
Active cation transport in human red cells
In: G Giebisch, D C Tosteson, H H Ussing(ed.)
Membrane Transport in Biology.
Berlin: Springer-Verlag, 1978. pp. 117-160.
Vol. 3., Transport across multi-membrane systems
(ISBN:3-540-08596-3) Chapter in Book/Study/Scientific
238.Pandey GN, Sarkadi B, Haas M, Gunn RB, Davis JM, Tosteson DC
Lithium transport pathways in human red blood cells
J GEN PHYSIOL 72: 233-247 (1978)
IF: 4.855
Journal Article/Article/Scientific
Independent citations: 147 Dependent (self-) citations: 15 All citations: 162
1977
239.Szász I, Sarkadi B, Gárdos G
Mechanism of Ca2+-dependent selective rapid K+-transport induced by propranolol in red cells
J MEMBRANE BIOL 35: 75-93 (1977)
IF: 3.453
Journal Article/Article/Scientific
Independent citations: 47 Dependent (self-) citations: 10 All citations: 57
240.Schubert A, Sarkadi B
Kinetic studies on the calcium-dependent potassium transport in human red blood cells
ACTA BIOCHIM BIOPHYS ACAD SCI HUNG 12: 207-216 (1977)
IF: 0.797
Journal Article/Article/Scientific
Independent citations: 5 Dependent (self-) citations: 2 All citations: 7
241.Sarkadi B, Szász I, Gerlóczy A, Gárdos G
Transport parameters and stoichiometry of active calcium ion extrusion in intact human red cells
BIOCHIM BIOPHYS ACTA 464: 93-107 (1977)
IF: 0.797
Journal Article/Article/Scientific
Independent citations: 129 Dependent (self-) citations: 13 All citations: 142
242.Gárdos G, Szász I, Sarkadi B
Effect of intracellular calcium on the cation transport processes in human red cells
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 34 / 36
Curriculum vitae Balázs Sarkadi
ACTA BIOL MED GER 36: 823-829 (1977)
IF: 0.499
Journal Article/Article/Scientific
Independent citations: 9 Dependent (self-) citations: 2 All citations: 11
1976
243.Sarkadi B, Szász I, Gárdos G
The use of ionophores of rapid loading of human red cells with radioactive cations for cation-pump studies
J MEMBRANE BIOL 26: 357-370 (1976)
IF: 3.444
Journal Article/Article/Scientific
Independent citations: 130 Dependent (self-) citations: 13 All citations: 143
1975
244.Gárdos G, Szász I, Sarkadi B
Mechanism of Ca-dependent K transport in human red cells
In: G Gárdos, I Szász(ed.)
Biomembranes: Structure and Function.
Amsterdam: Akadémiai Kiadó - Elsevier Science Publishers, 1975. pp. 167-180.
(Proceedings of meetings of the federation of european bi ochemical societies; 35.)
(ISBN:9780444109354) Chapter in Book/Conference paper/Scientific
1974
245.Szász I, Sarkadi B, Gárdos G
Erythrocyte parameters during induced CA-2+-dependent rapid K+-efflux: optimum conditions for kinetic analysis
HAEMATOLOGIA (BUDAPEST) 8: 143-151 (1974)
Journal Article/Article/Scientific
246.Goldschmidt B, Sarkadi B, Gárdos G, Matlary A
Platelet producton and survival in cyanotic congenital heart disease
SCAND J HAEMATOL 13: 110-115 (1974)
IF: 1.367
Journal Article/Article/Scientific
1972
247.Sarkadi B, Schubert A
Energy consumption of active sodium transport in isolated frog skin
ACTA BIOCHIM BIOPHYS ACAD SCI HUNG 7: 367-376 (1972)
Journal Article/Article/Scientific
1971
248.Spät A, Sarkadi B, Intody Z, Korner A, Szanto J
Effect of renal papillary lipids and prostaglandin E2 on corticosteroid production in the rat
ACTA PHYSIOL ACAD SCI HUNG 40: 187-199 (1971)
Journal Article/Article/Scientific
Independent citations: 8 Dependent (self-) citations: 9 All citations: 17
Projects Ongoing Research Support
Hungarian Research Fund (OTKA) 115375, 09.01. 2015 - 08.31.2019
Regulation of the expression of ABC transporters in normal human stem cells.
Role: PI grant support approx. USD 400,000
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 35 / 36
Curriculum vitae Balázs Sarkadi
Memberships 1982- Hungarian Society of Biochemistry (vice-president);
1982- Federation of European Biochemical Societies (FEBS - president, 2006-2007)
1988- Member, American Physiological Society
1992- Member, American Society of Biochemistry and Molecular Biology
1992- Member, American Association of Cancer Research
1996- International Cell Research Organization, Panel Convener, Vice President,
2000- Member, American Society of Cell Biology
2006- Member, Academia Europeae
2010 - Full member of the Hungarian Academy of Sciences,
2017- Vice president, International Transmembrane Transporter Society
Other Relevant Information I spent several years as a post-doc and then as a visiting scientist at major universities and research centers in the United States and Canada. I am head of the Membrane Research Group and professorat Semmelweis University, member of the Hungarian Academy of Sciences, past president of the Federation of European Biochemical Societies (FEBS), member of several international research societies and the Academia Europeae. My research has been focusing on the investigation of ABC membrane transporters, which play a major role in the multidrug resistance of cancer, in general pharmacology, and in stem cell function. With my colleagues we have devised new methods for the functional analysis of ABC transporter proteins, and developed compounds that modulate their function.
I have published more than 150 papers in international scientific journals, with a citation number over 9,500. My current work is focusing on the role of ABC multidrug transporters in the cellular effects of targeted anticancer agents, and the function of these transporters in normal and cancer stem cells. I am a Research Professor of Semmelweis University, Budapest, Hungary, actively participating in the education of graduate and postgraduate students. I served as a supervisor for 14 Ph.D. students, whoalready successfully obtained their doctoral degrees.
Awards:
1982, 1986, Research Award of the Hungarian Academy of Sciences
1995-2004 Howard Hughes International Fellowship
1995 Bela Tanko Award (Hung. Biochem. Soc.)
1997-2000 Szechenyi Research Professorship, Hungary
2000 Fulbright Senior Research Fellowship
2003 Academy Award, Hungary
2004- Membership, Hungarian Academy of Sciences
2005- Membership, Academia Europaea
2006 Denis Gabor Award
2009 Ipolyi Arnold Award, Hungary
21/11/17 © European Union, 2002-2017 | http://europass.cedefop.europa.eu Page 36 / 36