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Percutaneous Intervention in Takayasu’s Aortoarteritis Dr Rajesh Vijayvergiya, MD, DM, FSCAI, FISES, FACC Associate Professor Cardiology Associate ProfessorCardiology PGIMER, Chandigarh. India India

Percutaneous Intervention in Takayasu’s Aorto arteritisCase History • 20 yrs old boy CR No. 4806371, presented in December 2011, with:‐ – HTN from 1 year on ACEI drug. –

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Page 1: Percutaneous Intervention in Takayasu’s Aorto arteritisCase History • 20 yrs old boy CR No. 4806371, presented in December 2011, with:‐ – HTN from 1 year on ACEI drug. –

Percutaneous Intervention in Takayasu’s Aorto‐arteritis

Dr Rajesh Vijayvergiya, MD, DM, FSCAI, FISES, FACC

Associate Professor CardiologyAssociate Professor‐CardiologyPGIMER, Chandigarh. 

IndiaIndia

Page 2: Percutaneous Intervention in Takayasu’s Aorto arteritisCase History • 20 yrs old boy CR No. 4806371, presented in December 2011, with:‐ – HTN from 1 year on ACEI drug. –

Case HistoryCase History

• 20 rs old bo CR No 4806371 presented in December 2011 ith• 20 yrs old boy CR No. 4806371, presented in December 2011, with:‐– HTN from 1 year on ACEI drug.– B/L upper limb claudication Rt > Lt. – Post meal abdominal pain from last 6 months.  

• Examination‐ BP in both UL – 110/80 mmHg, feeble brachial arteries, BP in both LL 170/80 mmHg. 

• Rt supra‐clavicular bruit +. Rest N.• 2‐D Echo Normal. CXR Normal.• Blood sugar 76mg% urea/Creatinine 22/0 6mm%• Blood sugar 76mg%, urea/Creatinine 22/0.6mm%, • ESR 20 mm in 1st hr, CRP negative• CT angio Abdominal aorta‐ 95% osteal stenosis of celiac trunk, 70% 

i f SMA 90% i f R R l Abd i lstenosis of SMA, 90% stenosis of Rt Renal artery. Abdominal aorta Normal.  

• Diagnosis‐ Takayasus Aortoarteritis (TAA) – inactive phase type III, i l i i h d bd i l linvolving aortic arch and abdominal aorta vessels.  

Page 3: Percutaneous Intervention in Takayasu’s Aorto arteritisCase History • 20 yrs old boy CR No. 4806371, presented in December 2011, with:‐ – HTN from 1 year on ACEI drug. –

AngiogramAngiogram

Rt SCA 90% diffuse long segment stenosis

26th Dec 2011

Page 4: Percutaneous Intervention in Takayasu’s Aorto arteritisCase History • 20 yrs old boy CR No. 4806371, presented in December 2011, with:‐ – HTN from 1 year on ACEI drug. –

AngiogramAngiogram

L SCA 70% i R RAS 90% L RA lLt SCA 70% stenosis

Coronaries, bilateral carotids were normal. 

Rt RAS 90%, Lt RA normal 

Page 5: Percutaneous Intervention in Takayasu’s Aorto arteritisCase History • 20 yrs old boy CR No. 4806371, presented in December 2011, with:‐ – HTN from 1 year on ACEI drug. –

AngiogramAngiogram 

Prox SMA 70% stenosisGradient of 50mmHg

CT 90% osteal stenosis, Retrograde filling from SMA

26th Dec 2011

Page 6: Percutaneous Intervention in Takayasu’s Aorto arteritisCase History • 20 yrs old boy CR No. 4806371, presented in December 2011, with:‐ – HTN from 1 year on ACEI drug. –

PTRA + StentingPTRA + Stenting

7F RDC Renal Guide (Medtronic), ATW Coronary guide wire. Lesion pre‐dilation with  2.5X20  then 5X20 mm balloon, 

26th Dec 2011

Very hard lesion, difficult to dilate it.  

Page 7: Percutaneous Intervention in Takayasu’s Aorto arteritisCase History • 20 yrs old boy CR No. 4806371, presented in December 2011, with:‐ – HTN from 1 year on ACEI drug. –

PTRA + StentingPTRA + Stenting

6X24 mm Genesis BES deployed at 12 atms. Ostium flared at 14 atms. p y

26th Dec 2011

Page 8: Percutaneous Intervention in Takayasu’s Aorto arteritisCase History • 20 yrs old boy CR No. 4806371, presented in December 2011, with:‐ – HTN from 1 year on ACEI drug. –

Rt Subclavian artery stentingRt Subclavian artery stenting

7F  long Sheath (Cook) for cannulation of Rt Subclavian artery. ATW id i th l iATW coronary guide wire across the lesion.Pre‐dilation with 5X20 mm balloon. – Hard lesion having difficulty in dilatation . 

26th Dec 2011

Page 9: Percutaneous Intervention in Takayasu’s Aorto arteritisCase History • 20 yrs old boy CR No. 4806371, presented in December 2011, with:‐ – HTN from 1 year on ACEI drug. –

Rt Subclavian artery stentingRt Subclavian artery stenting

Wire changed to 0.018 inch Road Runner wire.7X120 mm Zilver Cooks SES deployed, post dilated with 5X20 mm Balloon.7X120 mm Zilver Cooks SES deployed, post dilated with 5X20 mm Balloon.Good flow achieved. 

Page 10: Percutaneous Intervention in Takayasu’s Aorto arteritisCase History • 20 yrs old boy CR No. 4806371, presented in December 2011, with:‐ – HTN from 1 year on ACEI drug. –

Lt Subclavian Artery stentingLt Subclavian Artery stenting

7F  long Sheath (Cook) for cannulation of Lt Subclavian artery. 0.018 inch Road Runner wire across the lesion.A 7X29 mm Genesis BES directly deployed at 14 atms, good flow achieved.Th di t i b th th ft t tiThere was no pressure gradient in both the arms after stenting. 

26th Dec 2011

Page 11: Percutaneous Intervention in Takayasu’s Aorto arteritisCase History • 20 yrs old boy CR No. 4806371, presented in December 2011, with:‐ – HTN from 1 year on ACEI drug. –

Mesenteric RevascularizationMesenteric Revascularization.

• Needs brachial approach for Celiac trunk stenting. g

• Performed in 2nd sitting. 

Page 12: Percutaneous Intervention in Takayasu’s Aorto arteritisCase History • 20 yrs old boy CR No. 4806371, presented in December 2011, with:‐ – HTN from 1 year on ACEI drug. –

Celiac trunk stentingCeliac trunk stenting

ll dil d S S f b l iPatent well dilated SES of Rt subclavian artery.  7 F Rt brachial long sheath.Celiac Trunk (CT ) cannulation with JR 3.5, 6F coronary catheter via femoral route.A 300 h l th 0 014 i h R dR i th l i i Rt b hi lA 300 cm exchange length 0.014 inch RoadRunner wire across the lesion via Rt brachial. CT lesion pre‐dilated with 4.5X15 mm balloon.  7X18 mm Genesis BES deployed. 5th Jan 2012

Page 13: Percutaneous Intervention in Takayasu’s Aorto arteritisCase History • 20 yrs old boy CR No. 4806371, presented in December 2011, with:‐ – HTN from 1 year on ACEI drug. –

SMA stentingSMA stenting

SMA lesion crossed with 0.014 inch Road runner wire. A 7X24 mm BES was deployed.Brisk flow achieved in SMA. 

5th Jan 2012

Page 14: Percutaneous Intervention in Takayasu’s Aorto arteritisCase History • 20 yrs old boy CR No. 4806371, presented in December 2011, with:‐ – HTN from 1 year on ACEI drug. –

Post intervention Abdominal Aortogram

5th Jan 2012

Page 15: Percutaneous Intervention in Takayasu’s Aorto arteritisCase History • 20 yrs old boy CR No. 4806371, presented in December 2011, with:‐ – HTN from 1 year on ACEI drug. –

ConclusionsConclusions 

• Young boy with inactive phase of TAA type III.

• Symptomatic chronic mesenteric ischemia,Symptomatic chronic mesenteric ischemia, bilateral UL claudication and secondary hypertension treated with percutaneoushypertension treated with percutaneous stenting. 

• 2 months follow‐up‐doing well.  

5th Jan 2012