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PEDIATRIC AND ADULT INFLUENZA WEBINAR: 2020-2021 FLU SEASON SEPTEMBER 2, 2020 Presenters: Shelly Doebler, MPH Stefanie Cole, BSN, RN, MPH 1

PEDIATRIC AND ADULT INFLUENZA WEBINAR: 2020-2021 FLU ... · Influenza-Associated Pediatric Deaths Became nationally reportable in 2004 for people younger than 18 years of age 2019-2020

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Page 1: PEDIATRIC AND ADULT INFLUENZA WEBINAR: 2020-2021 FLU ... · Influenza-Associated Pediatric Deaths Became nationally reportable in 2004 for people younger than 18 years of age 2019-2020

PEDIATRIC AND ADULT INFLUENZA WEBINAR: 2020-2021 FLU SEASON

SEPTEMBER 2, 2020

Presenters: Shelly Doebler, MPH

Stefanie Cole, BSN, RN, MPH

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Speaker Disclosures

■ Speakers for today’s webinar: – Stefanie Cole, BSN, RN, MPH, Immunization Nurse Educator,

MDHHS– Shelly Doebler, MPH, Influenza Epidemiologist, MDHHS

■ All faculty presenters have nothing to disclose.

■ No commercial support was provided for this CME/PCE activity.

3

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CME Information

■ This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of MSU and MDHHS. MSU is accredited by the ACCME to provide continuing education for physicians.

■ Michigan State University designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

4

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PCE Information

■ This activity has been approved to meet knowledge-based educational needs and 1.0 Pharmacy Continuing Education (PCE) Credit will be awarded to participants by the Michigan Pharmacists Association (MPA).

■ Michigan Pharmacists Association is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a provider of continuing pharmacy education.

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Pediatric and Adult Influenza Webinar Objectives ■ Discuss influenza disease rates,

surveillance, and vaccine coverage levels

■ Discuss influenza vaccine recommendations

■ Identify strategies to improve influenza vaccination rates

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Influenza Disease Burden■ Difficult to predict severity and timing■ Rates of serious illness and death greatest in:

– Persons aged 65 years and older– Children <5 years, especially children

less than 2 years of age– Persons with medical conditions that put

them at high risk■ Only half develop classic clinical flu symptoms■ 5 categories of surveillance: viral, mortality,

hospitalization, geographic spread, and outpatient influenza-like illness (ILINet)2

– We need more ILINet providers!– For more information email,

[email protected]

7

1. www.cdc.gov/flu/about/burden/preliminary-in-season-estimates.htm2. www.michigan.gov/mdhhs/0,5885,7-339-71550_2955_22779-121722--,00.html

Deaths: 24,000 – 62,000

Hospitalizations: 410,000 - 740,000

Cases: 39,000,000 -56,000,000

National Influenza Burden Estimates 2019-2020 Season1

Page 7: PEDIATRIC AND ADULT INFLUENZA WEBINAR: 2020-2021 FLU ... · Influenza-Associated Pediatric Deaths Became nationally reportable in 2004 for people younger than 18 years of age 2019-2020

Influenza-Associated Pediatric Deaths■ Became nationally reportable in 2004 for people younger than 18 years of

age

■ 2019-2020 flu season: 188 pediatric deaths– 6 deaths confirmed in Michigan1

■ “Influenza-Associated Pediatric Deaths in the United States, 2010–20162”– Published February 2018– Average annual number: 113■ Highest incident rate among children < 6 months (0.66 per 100,000)

– 65% died within a week of symptom onset– Half had no pre-existing medical conditions– Only 31% of children ≥ 6 months had received any flu vaccinations

8

1. www.cdc.gov/flu/weekly/index.htm#ILIMap2. https://pediatrics.aappublications.org/content/141/4/e20172918

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2020-2021 Influenza Vaccination Strains■ Egg-based vaccines will include:

– A/Guangdong-Maonan/SWL1536/2019 (H1N1)pdm09-like virus (NEW)– A/Hong Kong/2671/2019 (H3N2)-like virus (NEW)– B/Washington/02/2019 (B/Victoria lineage)-like virus (NEW)– B/Phuket/3073/2013-like (Yamagata lineage) virus (Quadrivalent only)

■ Quadrivalent cell- or recombinant-based vaccines will include: – A/Hawaii/70/2019 (H1N1)pdm09-like virus (NEW)– A/Hong Kong/45/2019 (H3N2)-like virus (NEW)– B/Washington/02/2019 (B/Victoria lineage)-like virus (NEW)– B/Phuket/3073/2013-like (Yamagata lineage) virus

9www.who.int/influenza/vaccines/virus/recommendations/2020-21_north/en/

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10www.cdc.gov/flu/weekly/index.htm

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2020-2021 SEASONAL INFLUENZA VACCINE RECOMMENDATIONSACIP RecommendationsFlu Vaccine TimingInfluenza Vaccine Products

11

Don’t forget to submit your questions in the Questions and Answers box!

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Influenza Recommendations

12www.cdc.gov/mmwr/volumes/69/rr/rr6908a1.htm

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Core Influenza Vaccine Recommendation

■ Has not changed since 2010■ Routine annual flu vaccination is recommended for ALL

persons aged 6 months and older who do not have contraindications

■ No preferential recommendation is made for one flu vaccine product over another for persons for whom more than one licensed, recommended, age-appropriate product is available

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Timing of Flu Vaccination

■ ACIP recommends that flu vaccination be offered by the end of October

■ Children aged 6 months through 8 years who need 2 doses should receive their 1st dose ASAP after vaccine becomes available to allow the 2nd dose to be received by the end of October– Minimum interval: 4 weeks

■ For those only needing 1 dose this season, early vaccination (i.e., July and August) is likely to be associated with suboptimal immunity before the end of the flu season, particularly among older adults

14

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Timing of Flu Vaccination, Cont’d.

■ Continue to vaccinate as long as flu viruses are circulating, and unexpired vaccine is available

■ No recommendation is made for revaccination later in the season for persons who have already been fully vaccinated

15This Photo by Unknown Author is licensed under CC BY-SA

Likelihood of persistence of

vaccine-induced protection

through the season

Avoiding missed opportunities to

vaccinate, or vaccinating after

onset of flu circulation occurs

Page 15: PEDIATRIC AND ADULT INFLUENZA WEBINAR: 2020-2021 FLU ... · Influenza-Associated Pediatric Deaths Became nationally reportable in 2004 for people younger than 18 years of age 2019-2020

Types of Influenza Vaccine Available in 2020-21 Season■ IIV = Inactivated Influenza Vaccine

– All standard-dose, unadjuvanted IIV is quadrivalent (IIV4)■ This included Cell-Culture Based (ccIIV4)

– Other types of IIV: High-Dose (HD-IIV4*) and Adjuvanted (aIIV3, aIIV4*)

■ RIV4 = Recombinant Influenza Vaccine, quadrivalent■ LAIV4 = Live, Attenuated Influenza Vaccine, quadrivalent

16*New flu vaccine licensures for the 2020-21 season!

Page 16: PEDIATRIC AND ADULT INFLUENZA WEBINAR: 2020-2021 FLU ... · Influenza-Associated Pediatric Deaths Became nationally reportable in 2004 for people younger than 18 years of age 2019-2020

A Look at IIV4

IIV4

4 flu strains: 2 A, 2 B

Egg-based, standard-dose (SD), unadjuvanted

Ages 6 months and older

For: healthy, underlying medical conditions, pregnant

Give intramuscularly (IM)

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Page 17: PEDIATRIC AND ADULT INFLUENZA WEBINAR: 2020-2021 FLU ... · Influenza-Associated Pediatric Deaths Became nationally reportable in 2004 for people younger than 18 years of age 2019-2020

A Look at HD-IIV4, aIIV4, and aIIV3HD-IIV4

(Fluzone® High-Dose Quadrivalent)

aIIV4 (Fluad® Quadrivalent)

aIIV3 (Fluad®)

4 flu strains: 2 A, 2 B 3 flu strains: 2 A, 1 B

Give intramuscularly (IM)

Ages 65 years and older

Has 4x more antigenthan SD flu vaccine

Adjuvant (MF59) added to create stronger immune response

For: healthy, underlying medical conditions18

Page 18: PEDIATRIC AND ADULT INFLUENZA WEBINAR: 2020-2021 FLU ... · Influenza-Associated Pediatric Deaths Became nationally reportable in 2004 for people younger than 18 years of age 2019-2020

A Look at ccIIV4 and RIV4ccIIV4

(Flucelvax® Quadrivalent)RIV4

(Flublok® Quadrivalent)

4 flu strains: 2 A, 2 BGive intramuscularly (IM)

Ages 4 years and older Ages 18 years and olderProduced in a mammalian

cell line Produced in an insect cell line

For persons who are healthy, have any underlying medical conditions, are pregnant

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Page 19: PEDIATRIC AND ADULT INFLUENZA WEBINAR: 2020-2021 FLU ... · Influenza-Associated Pediatric Deaths Became nationally reportable in 2004 for people younger than 18 years of age 2019-2020

A Look at LAIV4

LAIV4 (FluMist® Quadrivalent)

4 flu strains: 2 A, 2 B

Administered intranasally (IN/NAS)

Ages 2-49 years (healthy, not pregnant)

20

Do not miss an opportunity to vaccinate, use any age-appropriate flu vaccine that is available!

Page 20: PEDIATRIC AND ADULT INFLUENZA WEBINAR: 2020-2021 FLU ... · Influenza-Associated Pediatric Deaths Became nationally reportable in 2004 for people younger than 18 years of age 2019-2020

U.S. Licensed Influenza Vaccines Available 2020-21

21Table credit to Dr. Grohskopf, CDC COCA Call 8/20/20, https://emergency.cdc.gov/coca/calls/index.asp

Vaccine Type 6-23 Months 2-3 Years 4-17 Years 18-49 Years 50-64 Years 65 Years +

IIV4s (egg)

Afluria QuadrivalentFluarix QuadrivalentFluLaval QuadrivalentFluzone Quadrivalent

ccIIV4 (cell) Flucelvax Quadrivalent

RIV4 (recombinant) Flublok Quadrivalent

Adjuvanted aIIV3 (egg) Fluad

Adjuvanted aIIV4 (egg)

Fluad Quadrivalent (NEW)

High-dose HD-IIV4 (egg)

Fluzone High-Dose Quadrivalent (NEW)

LAIV4 (egg) FluMist Quadrivalent (healthy, non-pregnant)

Page 21: PEDIATRIC AND ADULT INFLUENZA WEBINAR: 2020-2021 FLU ... · Influenza-Associated Pediatric Deaths Became nationally reportable in 2004 for people younger than 18 years of age 2019-2020

2020-21 Flu Vaccine Presentation Chart

■ Lists flu vaccine products, brand names, age indications, product presentations

■ Multi-dose vials: – Afluria: once stopper has been

pierced, discard vial after 28 days or 20 needle punctures to the vial, whichever comes first

– Fluzone: max 10 doses can be withdrawn (even if 0.25 mL doses)

– Flucelvax: use up until exp. date

22

www.michigan.gov/flu→ Resources → Health Professional Resources

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FLU VACCINE GUIDANCE FOR USE IN CHILDREN

Pediatric Dose VolumesNumber of Doses Needed in 2020-21 Season

23

Page 23: PEDIATRIC AND ADULT INFLUENZA WEBINAR: 2020-2021 FLU ... · Influenza-Associated Pediatric Deaths Became nationally reportable in 2004 for people younger than 18 years of age 2019-2020

Influenza Vaccine Dose Volumes■ Children aged 6 through 35 months may receive any of the four IIV4

products licensed for this age group

■ For 6-35 months, dose volume depends on the flu vaccine product that is administered

24

If You’re Using This Vaccine... Dose Volume for Ages 6-35 Months

Afluria (Seqirus) 0.25 mL per dose

Fluarix or FluLaval (GSK) 0.5 mL per dose

Fluzone (Sanofi Pasteur)0.25 mL OR 0.5 mL per dose

*No preference is expressed for either dose volume

For children aged 3 years and older, dose volume for SD-IIV 0.5 mL regardless of the flu vaccine product being administered

Page 24: PEDIATRIC AND ADULT INFLUENZA WEBINAR: 2020-2021 FLU ... · Influenza-Associated Pediatric Deaths Became nationally reportable in 2004 for people younger than 18 years of age 2019-2020

Influenza Vaccine Dose Volumes, Cont’d.■ For IIV4, the needed volume for a child 6-35 months may be administered from a

manufacturer supplied prefilled syringe, a single-dose vial, or a multi-dose vial

■ If a 0.5 mL single-dose vial is used for a 0.25 mL dose for a child 6-35 months, only administer half the volume, the other half should be discarded

Vaccine Administration Error Case Study: ■ A 6-month-old was inadvertently given a 0.25 mL dose of FluLaval (or Fluarix) rather

than the recommended 0.5 mL dose. What do you do? – If you recognize the error that same day, give a second 0.25 mL dose of the

product that was used. This equals a full dose for this child. If the error is not discovered until the next day, the 6-month-old needs to be revaccinated with a full dose of IIV4 ASAP (this will be the 1st dose of this infant’s 2-dose series).

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Page 25: PEDIATRIC AND ADULT INFLUENZA WEBINAR: 2020-2021 FLU ... · Influenza-Associated Pediatric Deaths Became nationally reportable in 2004 for people younger than 18 years of age 2019-2020

2020-21 Flu VaccineDose Volumes for Children

■ Prevent flu vaccine administration errors in children

■ Covers pediatric dosage by vaccine, how to correct vaccine administration errors

26

www.michigan.gov/flu→ Resources → Health Professional Resources

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■ # of doses needed is based on child’s age at time of 1st dose of 2020-21 flu vaccine and # of doses of flu vaccine received in previous seasons

■ How many seasonal (i.e., trivalent, quadrivalent) flu vaccines received before 7/1/2020

– If 2 or more doses: give 1 dose this season– If only 1 dose or has NEVER received flu vaccine:

give 2 doses this season (separate by 4 weeks)■ 2 doses do not need to be from the same season or

consecutive seasons, need to be spaced at least 4 weeks apart

■ Give 1st dose as soon as possible after vaccine is available, 2nd dose by end of October

■ If the child turns 9 years between dose 1 and dose 2, still give dose 2

2-Dose Recommendation: 6 Months-8 Years

27

MCIR is programmed for 2-dose assessment. Make sure to use MCIR!www.michigan.gov/flu→ Resources → Health Professional Resources

Page 27: PEDIATRIC AND ADULT INFLUENZA WEBINAR: 2020-2021 FLU ... · Influenza-Associated Pediatric Deaths Became nationally reportable in 2004 for people younger than 18 years of age 2019-2020

FLU VACCINE & PREGNANCY

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Pregnancy Flu Vaccine Recommendation■ Pregnant and postpartum women have been observed to be at

higher risk for severe illness and complications from flu, particularly during 2nd and 3rd trimesters

■ Flu vaccination during pregnancy lowers risk of flu hospitalization in pregnant women by average 40%, babies <6 months old by average 72%

■ ACIP and ACOG recommend that:– All women who are pregnant or who might be pregnant or

postpartum during the flu season receive flu vaccine– Any licensed, recommended, and age-appropriate IIV or RIV4

may be used (LAIV4 should not be used during pregnancy)– Administer at any time during pregnancy, before and during

the flu season

29

www.acog.org/Clinical-Guidance-and-Publications/Committee-Opinions/Committee-on-Obstetric-Practice/Influenza-Vaccination-During-Pregnancy

www.cdc.gov/flu/highrisk/pregnant.htm – Pregnant Women & Flu Vaccine Studies

Page 29: PEDIATRIC AND ADULT INFLUENZA WEBINAR: 2020-2021 FLU ... · Influenza-Associated Pediatric Deaths Became nationally reportable in 2004 for people younger than 18 years of age 2019-2020

INFLUENZA VACCINATION ADMINISTRATION

Screening for VaccinationEgg AllergyVaccine Administration

30

Don’t forget to submit your questions in the Questions and Answers box!

Page 30: PEDIATRIC AND ADULT INFLUENZA WEBINAR: 2020-2021 FLU ... · Influenza-Associated Pediatric Deaths Became nationally reportable in 2004 for people younger than 18 years of age 2019-2020

Screening for Contraindications and Precautions■ Screen for contraindications and

precautions every time vaccines are indicated

■ Use a standardized form■ Help prevent vaccine errors

■ Follow only valid contraindications and precautions

■ Document any permanent or temporary contraindications/precautions in the chart/EMR

31www.immunize.org

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Contraindications to Flu Vaccine■ IIV/RIV/LAIV: History of severe allergic reaction to the vaccine or any of its components*

■ LAIV: – Concomitant aspirin- or salicylate-containing therapy (children and adolescents)– Children aged 2-4 years with a history of asthma or documented wheezing episode in the past 12

months– Immunocompromised due to any cause, including immunosuppression caused by medications,

congenital or acquired immunodeficiency states, HIV infection, anatomic asplenia, or functional asplenia (e.g., sickle cell anemia)

– Close contacts/caregivers of severely immunosuppressed persons who require a protected environment

– Pregnancy– Active communication between CSF and oropharynx, nasopharynx, nose, or ear or any other cranial

CSF leak– Cochlear implants– Receipt of flu antivirals within: previous 48 hours (oseltamivir, zanamivir), previous 5 days (peramivir),

previous 17 days (baloxavir)

32

*However, ACIP recommends that persons with history of egg allergy may receive any flu vaccine otherwise appropriate for their age/health status

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Precautions to Flu Vaccine

■ IIV/RIV/LAIV: Moderate or severe acute illness with or without fever and history of Guillain-Barré syndrome within 6 weeks of previous flu vaccine

■ LAIV:– Asthma in persons aged 5 years and older– Other underlying medical conditions that might predispose to

complications after influenza infection (e.g., chronic pulmonary, cardiovascular [excluding isolated hypertension], renal, hepatic, neurologic, hematologic, or metabolic disorders [including diabetes mellitus])

33

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Quick Looks at Using IIV, ccIIV, RIV, and LAIV

34

www.michigan.gov/flu→ Resources → Health Professional Resourceswww.michigan.gov/VaccineQuickLooks

Page 34: PEDIATRIC AND ADULT INFLUENZA WEBINAR: 2020-2021 FLU ... · Influenza-Associated Pediatric Deaths Became nationally reportable in 2004 for people younger than 18 years of age 2019-2020

Flu Vaccination for Persons With Egg Allergy

■ History of egg allergy and only hives after exposure to egg should receive flu vaccine

– Use any licensed, recommended vaccine (i.e., any IIV, RIV4, or LAIV4) otherwise appropriate for age/health status

■ History of egg allergy and symptoms other than hives (e.g., angioedema or swelling, respiratory distress, lightheadedness, or recurrent vomiting) or required epinephrine/another emergency medical intervention: may receive flu vaccine

– May receive any licensed, recommended vaccine (i.e., any IIV, RIV4, LAIV4) otherwise appropriate for age/health status

– If a vaccine other than ccIIV4 or RIV4 is used, administer it in an inpatient or outpatient medical setting

– Supervised by health care provider able to recognize and manage severe allergic reactions

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Flu Vaccine & Egg Allergy, Cont’d.■ For persons who report egg allergy, it is not

recommended to administer divided doses of flu vaccine or to do skin testing with the vaccine before administration

■ No post-vaccination observation period is recommended specifically for egg-allergic persons

■ Reminder: previous severe allergic reaction to flu vaccine is a contraindication to future receipt of the vaccine

36www.michigan.gov/flu→ Resources → Health Professional Resources

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Flu Vaccine Administration

■ Covers intramuscular (IM) and intranasal (IN/NAS) administration techniques

■ Do skills check-offs for staff in your office

37

www.michigan.gov/flu→ Resources → Health Professional Resources

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Shoulder Injury Related to Vaccine Administration (SIRVA)■ Inflammatory reaction resulting

from incorrect administration of a vaccine intended for IM injection in deltoid, into/around the underlying bursa of the shoulder

■ Causes shoulder pain and limited range of motion

■ Symptom onset occurs ≤ 48 hours after vaccine administration

38

Images courtesy of CDC

IAC Skills Checklist for Immunization: www.immunize.org/catg.d/p7010.pdf

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CDC Infographic: Preventing SIRVA

■ CDC resource on vaccine administration to prevent SIRVA

■ Help reduce errors

■ Skills check off with staff

39

Order FREE at: www.healthymichigan.com→Immunizations → IM163

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Flu Vaccine Information Statements (VIS)

■ Current IIV/RIV and LAIV VIS edition dates: 8/15/19

– These are “interim” versions and will be replaced with “final” versions, expected late 2020.

■ To access Michigan VISs (includes language on MCIR), go to www.michigan.gov/VIS

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TREATMENT OF INFLUENZATreating Cases of InfluenzaPrescribing Antivirals

41

Don’t forget to submit your questions in the Questions and Answers box!

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Treatment for Patients with Influenza■ Antiviral treatment is recommended as soon as possible for any patient with

suspected or confirmed flu who: – Is hospitalized– Has severe, complicated, or progressive illness– Is at higher risk for flu complications

■ Decision to start antiviral treatment should not wait for lab confirmation of flu

■ Clinical benefit is greatest when treatment is administered early, within 48 hours of illness onset

– Antivirals can be prescribed to persons with illness onset greater than 48 hours

■ A history of flu vaccination does not rule out the possibility of influenza infection or the need to use antivirals to treat flu

42www.cdc.gov/flu/professionals/antivirals/summary-clinicians.htm

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Who Should Be Treated With Flu Antivirals?

■ Children younger than 2 years, adults 65 years and older

■ Persons with chronic pulmonary, cardiovascular, renal, hepatic, hematological, and metabolic disorders, or neurologic and neurodevelopment conditions

■ Persons with immunosuppression, including caused by medications or HIV infection

■ Women who are pregnant or postpartum (within 2 weeks of delivery)

■ Younger than 19 years on long-term aspirin or salicylate therapy

■ American Indians and Alaska Natives

■ BMI ≥ 40

■ Residents of nursing homes and other chronic care facilities

43www.cdc.gov/flu/professionals/antivirals/summary-clinicians.htm

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44

ANTIVIRAL AGENT USE (# OF DAYS) RECOMMENDED FORNOT RECOMMENDED

FOR USE IN

Oseltamivir/Tamiflu®

(oral)

Treatment (5) 2 weeks & older N/A

Chemoprophylaxis (7) 3 months & older N/A

Zanamivir/Relenza®

(inhaled)

Treatment (5) 7 years & older People with underlying respiratory disease (e.g., asthma, COPD)

Chemoprophylaxis (7) 5 years & older People with underlying respiratory disease (e.g., asthma, COPD)

Peramivir/Rapivab®

(IV)

Treatment (1) 2 years & older N/A

Chemoprophylaxis (N/A) Not recommended N/A

Baloxavir/Xofluza®

(oral)

Treatment (1) 12 years & older N/A

Chemoprophylaxis (N/A) Not recommended N/A

www.cdc.gov/flu/professionals/antivirals/summary-clinicians.htm

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FLU VACCINE CONSIDERATIONS DURING COVID-19

45

Don’t forget to submit your questions in the Questions and Answers box!

Page 45: PEDIATRIC AND ADULT INFLUENZA WEBINAR: 2020-2021 FLU ... · Influenza-Associated Pediatric Deaths Became nationally reportable in 2004 for people younger than 18 years of age 2019-2020

Giving Flu Vaccine During COVID-19■ Screen for COVID-19 symptoms and

contact with cases prior to and upon arrival

■ Require face coverings for those 2 years and older

■ Implement physical distancing strategies

■ Providers: always wear medical facemasks, eye protection based on level of community transmission

■ When administering LAIV4:– Wear gloves

46www.cdc.gov/vaccines/pandemic-guidance/index.html

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Guidance for Off-Site Vaccination Clinics

■ Curbside or drive-through clinics– For children aged 6

months and older, have the parent remove from car seat and hold

– Direct drivers to a waiting area for 15 minutes after vaccination and check before they leave

47www.cdc.gov/vaccines/hcp/admin/mass-clinic-activities/index.html

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Influenza Vaccination of Persons with COVID-19■ Because SARS-CoV-2 is a novel coronavirus, clinical experience with

flu vaccination of persons with COVID-19 is limited

■ For someone who has acute illness with suspected or lab-confirmed COVID-19, clinicians can consider delaying flu vaccination until the patient is no longer acutely ill

■ If flu vaccination is delayed, patients should be reminded to return for flu vaccination once they have recovered from their acute illness

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MDHHS Vaccination & COVID-19 Resources

www.michigan.gov/VaccinesDuringCOVID

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INFLUENZA VACCINATION COVERAGE LEVELS AND STRATEGIES TO INCREASE COVERAGE

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Don’t forget to submit your questions in the Questions and Answers box!

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Michigan Influenza Vaccination Coverage, Select Ages, According to National Surveys and MCIR, 2011-2019

15

25

35

45

55

65

75

2011-12 2012-13 2013-14 2014-15 2015-16 2016-17 2017-18 2018-196mos and older 6mos and older (MCIR) 6mos-4 yrs

13-17yrs 18-49yrs HR* 65+

51*HR = High Risk; data available at: www.cdc.gov/flu/fluvaxview/reportshtml/trends/index.html

§ Minimal improvement over 8 season

§ “Everyone, every year” § Overall coverage remains

< 50%§ Healthy People 2020 goals

§ 70% for healthy adults (18+ years) and children 6 months through 17 years of age

§ MCIR estimates below national estimates for MI coverage

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Focus Area #1: 2-Dose Coverage ■ 2019-20 coverage levels in Michigan children, MCIR data

■ Children 6 months through 8 years of age complete (1 or 2 doses)– Only 32.8% complete for the season (1 or 2 doses)

(341,107/1,039,707)

■ Of the 528,656 children recommended 2 doses– 11.7% (62,038) received both doses– County range: 4.4% - 21.6%

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Methods to Improve Flu Coverage in Young Children ■ Initiate the conversation with parents/patients

about the importance of flu vaccine– Tell a personal story– Alana’s Foundation:

www.alanasfoundation.org/– Families Fighting Flu:

www.familiesfightingflu.org/

■ Ensure children who need 2 doses get their first dose early

■ No missed opportunities– Assess patients during every visit– Provide a strong recommendation and

offer flu vaccine to every patient

■ Routine vaccination hesitancy1: 6%

■ Hesitancy for flu vaccine: 26%

■ Parent hesitation2:– Perceived low vaccine

effectiveness– Safety concerns – Perception that flu vaccine

causes the flu

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1. Kempe, A. et al., Pediatrics, 2020 Retrieved from https://doi.org/10.1542/peds.2019-38522. De St. Maurice, A. et al., Pediatrics, 2020 Retrieved from https://doi.org/10.1542/peds.2020-17703. MDHHS Clearinghouse: www.healthymichigan.com

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Focus Area #2: Pregnant Women■ About half of pregnant women

receive a flu vaccine1

– Average 53.7% coverage from 2010-11 to 2017-18 flu seasons

– 65.7% offered vaccination and received the flu vaccine

– 26.7% of women reported receiving no recommendation; higher among Black women, high school diploma, below poverty line

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1. www.cdc.gov/mmwr/volumes/68/wr/mm6840e1.htm2. www.cdc.gov/flu/fluvaxview/pregnant-women-nov2017.htm

0% 10% 20% 30%

Concerned about safetyrisks to self

Not concerned about gettingthe flu

Concerned about safetyrisks to baby

Concerned about selfgetting sick or side effects

Does not think fluvaccination is effective

Reported main reason for not receiving flu vaccination among women pregnant any time August 1- November 8, 2017, who do not intend to receive flu vaccination for the rest of the flu season, Internet Panel Survey, United States (n=663)2

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Methods to Improve Coverage in Pregnant Women■ Ensure you are giving a strong recommendation

– 2016 American College of Obstetricians and Gynecologists (ACOG) study1

■ All medical providers reported giving recommendations for the vaccine– Only 85% of patients reported receiving a

recommendation

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1. www.ncbi.nlm.nih.gov/pmc/articles/PMC4983379/2. Created by John Parrish-Sprowl- Professor of Communication Studies; Director, Global Health Communication Center, Indiana University3. Opel et al. The Architecture of Provider-Parent Vaccine Discussions at Health Supervision Visits. Pediatrics. 2013;132(6):1037–1046. - July 01, 20144. www.cdc.gov/flu/about/burden-averted/2018-2019.htm

■ AIMS Method2: – Announce: vaccination will happen, assume they are ready to vaccinate– Inquire: seek to understand the person by asking about their concerns– Mirror: make sure they know you understand their concerns by mirroring but not

repeating and asking questions – Secure: consolidate every conversation by securing their trust

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56Order FREE at: www.healthymichigan.com

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Focus Area #3: Underlying Medical Conditions and Racial/Ethnic Disparities

■ Persons of any age– Diabetes, asthma, heart

disease, neurological conditions, and more2

■ Racial/ethnic disparities observed in persons with chronic conditions

■ American Indian/Alaskan Native (AI/AN) seem to be at higher risk for flu complications

57

1. www.cdc.gov/flu/fluvaxview/coverage-1819estimates.htmwww.cdc.gov/flu/about/disease/high_risk.htm

US Children (6 mos-17 yrs)

US Adults (18+ yrs)

All persons MI (6 mos +)

Non-Hispanic White

60.9 48.7 47.5

Non-Hispanic Black

59.8 39.4 39.8

Hispanic 66.3 37.1 49.9

Asian 71.2 44.0 -

AI/AN 58.5 37.6 -

Other/Multiple 60.3 39.7 42.1

Flu Vaccination Coverage by Race/Ethnicity, Children and Adults, US, MI, 2018-2019 Season1

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Addressing Chronic Conditions and Disparities■ Disparities result from individual attitudes

and beliefs, social norms, and health care practices1

■ Engagement is critical ■ Tailor messages to your audience■ Leverage local capacity■ Translated materials■ Culturally appropriate education

■ CDC materials addressing specific chronic conditions2

■ HCP Toolkit3

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1. www.ncbi.nlm.nih.gov/pubmed/289336192. www.cdc.gov/vaccines/hcp/adults/for-patients/health-conditions.html3. www.cdc.gov/flu/professionals/vaccination/prepare-practice-tools.htm

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And Remember

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Resources Throughout the Season

■ MI Flu Focus– Weekly flu updates during the flu

season – Includes surveillance system

updates, flu updates of interest, flu journal articles, and other flu news

– To receive MI Flu Focus email Shelly Doebler ([email protected]) with the subject line MI Flu Focus

■ Seasonal Flu Posters: – Order free at:

www.healthymichigan.com

60

www.michigan.gov/mdhhs/0,5885,7-339-73970_71692_71696-537640--,00.html

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Go to www.Michigan.gov/flu

and click on Resources to find all our updated

handouts!

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To Obtain MPA PCE Credit

§ Register as a user on the MPA website at michiganpharmacists.org with first name, last name, e-mail address, and password

§ Complete post-test and evaluation by September 16, 2020 at https://www.michiganpharmacists.org/education/20-318

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Thank you for your attendance!■ A survey link will be sent out to all registrants

■ Physicians/nurses, to obtain 1 AMA PRA Category 1 Credit for participating today:

– Complete the post-test within MSU’s evaluation by logging in to https://cmetracker.net/MSU

– Needs to be completed by September 30, 2020– If you have any questions, contact Connie DeMars at [email protected]

■ If we don’t have time to address your questions:– Stefanie Cole: [email protected]– Michelle Doebler: [email protected]

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The webinar recording & slides will be posted soon for 2 weeks only at

www.michigan.gov/flu→ Resources → Health Professionals Resources.

Check that site frequently!