PATHOLOGY OF THE SKIN. PERINATAL PATHOLOGY, PATHOLOGY OF ... PATHOLOGY OF THE SKIN. PERINATAL PATHOLOGY,

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  • PATHOLOGY OF THE SKIN.

    PERINATAL PATHOLOGY,

    PATHOLOGY OF THE

    NEWBORN AND INFANT

    XIII. practical training

    3rd year General Medicine

  • Inflammatory dermatosis

     Spongiotic dermatosis

     Psoriasiform dermatosis

     Vesiculobulous dermatosis

     Cytotoxic dermatosis

     Angiocentric dermatosis

     Granulocytic dermatosis

     Granulomatous dermatosis

     Paniculitis

  • Spongiotic dermatitis (subacute eczema dermatitis)

  • Psoriasis

     Chronic course of disease (hyperproliferation of epidermis)

     Hyperkeratosis

     Parakeratosis

     Papillomatosis

     Neutrophils in stratum corneum

     Different forms:

    papules, plaques, erythrodermia,

    alteration of nails, hyperpigmentation

     General symptoms, arthropathy

  • Psoriasis

  • Psoriasis,

    erythroderma

  • Psoriasis

  • Psoriasis

  • Psoriasis

  • Psoriasis

    guttata

  • Psoriasis, chronic alteration of nails

  • Psoriasis palmaris (palmoplantaris)

  • Psoriasis

    1

    1

    2

    2

    3

    1 acanthosis

    2 compact hyperkeratosis

    with parakeratosis

    3 stratum granulosum is absent

  • Psoriasis, microabscessus of Munro´s (residues of neutrophil leukocytes in stratum corneum)

    parakeratotic lamellae

    with neutrophil residues

  • Psoriasis pustulosa palmoplantaris

    intraepidermal pustule, acanthosis

  • TBC, Lupus vulgaris

  • TBC, Lupus vulgaris

  • TBC, Lupus vulgaris, TBC verrucosa

    tuberculous granulomas with

    multiple Langhan’s cells

  • Atheroma of the skin with inflammatory and giant cell reaction

  • Verruca vulgaris

  • Verruca vulgaris

  • Verruca vulgaris

    1

    2

    3

    1 hyperkeratosis

    2 papilomatosis

    3 parakeratosis

  • Verruca vulgaris

    1

    1 parakeratosis

  • Molluscum contagiosum

  • Molluscum contagiosum

  • Seborrheic keratosis (verruca)

  • Seborrheic keratosis (verruca)

  • Seborrheic keratosis (verruca)

    1 2

    1 hinges of proliferating basaloid cells, 2 abruptive keratosis

  • Seborrheic keratosis (verruca)

    1 proliferating basaloid cells, melanin

    2 abruptive keratosis

  • Bowen’s dermatosis

  • Bowen’s dermatosis

    dysplastic, polymorphic keratinocytes (spread in adnexal epithelium)

  • Bowen’s dermatosis

    dysplastic, polymorphic keratinocytes in groups

  • Bowen’s dermatosis

    acanthosis,

    hyperkeratosis with parakeratosis

  • Squamous cell carcinoma

  • Keratinizing squamous cell carcinoma

  • Keratinizing squamous cell carcinoma

    1

    2

    1 tumour infiltration, 2 hyperkeratosis, acanthosis

  • Keratinizing squamous cell carcinoma

    1

    2

    2

    2

    1 keratinization in tumour hinge, 2 mitosis

  • Basal cell carcinoma (Basalioma)

  • Basal cell carcinoma

  • Basal cell carcinoma

  • Basalioma terebrans

  • Basal cell carcinoma

    Hinges of basaloid tumour epithelium, pigmentation (melanin)

    1 fissure between tumour epithelium and fibrous stroma of

    corium

    1

  • Basal cell carcinoma

    1

    2

    1 tumour hinges

    2 pigment

  • Basal cell carcinoma

    1 fissure between tumour epithelium and

    fibrous stroma of corium 1

  • Basal cell carcinoma with pigment

  • Basal cell carcinoma, superficial

    multiple focuses

    lymphocytic infiltrate

    in base

  • Basal cell carcinoma, infiltrating (morphea type)

    1

    2

    1 infiltrating tumour hinges, 2 sclerotic fibrous tissue

    3 inflammatory infiltrate

    3

    1

    1

  • Junctional nevocellular nevus

  • Intradermal nevocellular nevus

  • Malignant melanoma

  • Malignant melanoma

  • Malignant melanoma

  • Malignant melanoma

  • Aspiration of amniotic fluid

  • Respiratory distress syndrome – hyaline membranes

  • Hyaline membranes

    1 Undeveloped alveoli

    2 Hyaline membranes

    1 2

    1

    1

    2

    2

  • Hyaline membranes

    1 Hyaline membranes

    1

    1

    1

    1

  • Respiratory distress syndrome – acute catarrhal

    bronchopneumonia