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Pain:
More than a
4-Letter WordKEMERY J. SIGMUND, MS, ATC, LAT
CCE, ASSISTANT PROFESSOR,
CONCORDIA UNIVERSITY WISCONSIN
PHD CANDIDATE, KINESIOLOGY
UNIVERSITY OF WISCONSIN-MILWAUKEE
Disclosures
Conflicts of Interest: None
No financial disclosures or conflicts
Viewpoints are my own
Patient information contained is not an
actual patient case or based on a real
person
Acknowledgements
Dr. Marie Hoeger Bement at Marquette University for photos and patient resources, support, & advising
Mary Beth Geiser, PT, DPT at Marquette University & Aurora Hospital Systems for photos and patient resources & support
Dr. Jennifer Earl-Boehm at UW-M for support & advising
Co-workers & students: Photos
What is Pain?
Pain is an unpleasant sensory & emotional experience
associated with actual or potential tissue damage. International Association for the Study of Pain (www.IASP-pain.org)
Pain is the 5th vital sign (The Joint Comission, 2001)
Pain is the number one reason people
seek medical care.
Effective pain management is a moral
imperative
Professional responsibility & Duty of
HCPs
Veterinarians receive 3X as much pain
education as doctors, therapists, and
human providers (all from IOM Report, 2011)
Pain is what the patient says it is (McCaffery,
1968)
Myths Surrounding Pain Assessment
I can only measure pain with Numeric Scales/ VAS
VAS/Numeric scales are not very accurate
If I assess pain, patients will focus on pain instead of function
My patient doesn’t have very high pain tolerance
I know what to expect w/ a given diagnosis
I don’t need to assess it- I can tell when my patient is “really in pain”
What do we know about pain?
A Case To Consider
Molly: HS track athlete with MTSS
Yesterday, pain was 6/10 and they had a meet –
successfully ran 3200m, 1600m; placed 2nd and 3rd,
respectively
Today: 8/10 pain; no visible signs of antalgic gait; walking
under own power; smiling & happy
Palp causes Molly to wince and pull leg away up the
medial tibial border
Pushes your hand away with sharp vs dull but you barely
touched her with the monofilament
Why might she be reporting 8/10
pain today and what do we do?
Biopsychosocial
Model
Biomedical
Model
Find the underlying
cause!
The issue is in the
tissue!
If it doesn’t work…
What is factors are
influencing her
pain? Our
assessment?
Consider 2 scenarios…
Is pain always indicative of tissue
damage?
NO.
When tissue damage does occur, do
you always feel pain?
NO.
Pain with no known tissue damage
Can cause increased nervous
system response
(AMPLIFICATION OF THE SIGNAL)
if persistent or continual
(Peripheral or Central):
Pain sensitization
Why does sensitization occur?
(The short version) Peripheral
Reduced nociceptor firing threshold
Increased nociceptor firing rate
Increased excitatory NT release
Increased receptive fields
Central (called Nociplasty)
Increased neuronal responsiveness
Reduced central/ Wide dynamic range neuron threshold
Communication between pain info (nociceptors) and touch receptors due to overload
Signs of pain sensitization:
Peripheral Nervous System Allodynia
Pain with a non-noxious
stimulus
Did we see this with
Molly?
Signs of Sensitization Hyperalgesia (Local or Remote)
Increased pain response to a noxious stimulus
Did we see this with
Molly?
Signs of Sensitization:
Central Nervous System Hyperalgesia (Remote)
Conditioned Pain
Modulation
Pain should inhibit pain
Impaired CPM Response=
when pain no longer inhibits
pain
Signs of Sensitization: Central
Temporal Summation
Increased pain with a constant
stimulus OR a repeated stimulus of
same intensity
Accentuated in those with
sensitization
Time (s)
0 20 40 60 80 100 120
Pa
in R
atin
gs
0
2
4
6
8
10Chronic
Pain
Healthy
Photos from the lab of Dr. Marie Hoeger
Bement, Marquette University
Clinical Assessment
Allodynia
Hyperalgesia
Temporal Summation
Conditioned Pain Modulation
Heat/Cold Sensation
So What?: Clinical Significance
1) Symptoms may not match behaviors
(they may not “look” like they’re in pain)
2) May appear to be overreactive: it’s a nervous
system issue
3) The “underlying cause” isn’t always malposition,
poor movement, etc.
Pain-movement Relationships
4) You can assess this and include it in notes!
5) You can treat this!
Pain Modulation: 4 M’s…
Medications
Doesn’t have to be all NSAIDs and Opioids
Modalities (affecting sensitization)
Options
Manual Therapy
Jt Mobs, Manips, Massage
Movement
Movement is therapy
…& 1 Big E
Patient Education
In chronic musculoskeletal conditions,
exercise + education can be more effective
than exercise alone
Patellofemoral Pain
Chronic LBP
Knee OA
One More Soapbox:
Opioid Epidemic & AT•“Playgrounds to Pills”:
•Every day (US,) 2500 youth (ages 12-17) abuse a Rx pain reliever for the 1st time.
•Avg age of first time drug use= 12
•2017: death by OD became the leading cause of death among teens in Waukesha County, surpassing traffic accidents
•OD deaths in WI have risen 72% since 2017
What’s your role? What can you do?
Pain in 5-minutes
Pain Specialists, Australia
https://www.youtube.com/watch?v=C_3phB93rvI
Other GREAT Resources
Spoon Theory: https://butyoudontlooksick.com/articles/written-
by-christine/the-spoon-theory/
Patient Education: Adriaan Louw- Why You Hurt
Flyers, This Year in Pain: www.IASP.org
References
International Association for the Study of Pain. Terminology. https://www.iasp-pain.org/terminology?navItemNumber=576
Baker DW. The Joint Commission’s Pain Standards: Origins and Evolution. Oakbrook Terrace, IL: The Joint Commission. 2001-2017.
Institute of Medicine. Relieving pain in America: a blueprint for transforming prevention, care, education, and research.http://www.nap.edu/catalog.php?record_id=13172.
Clauw DJ. Diagnosing and treating chronic musculoskeletal pain based on the underlying mechanism(s) Best Pract Res ClinRheumatol. 2015; 29(1):6-19
Woolf CJ. Central sensitization: implications for the diagnosis and treatment of pain. Pain. 2011, 152 (3S) S2-15.
Resources
Fillingim RB, Loeser JD, Baron R, Edwards RR. Assessment of chronic
pain: Domains, methods, and mechanisms. J Pain. 2016; 17(9S): T10-
20.
Kennedy DL, Kemp HI, Ridout D, Yarnitsky D, Rice AS. Reliability of
conditioned pain modulation: a systematic review. Pain. 2016;
157(11): 184-192
Merkle SL, Sluka KA, Frey-Law LA. The interaction between pain and
movement. J Hand Ther. 2018; In Press.