IntroductionThe need to assess the real health eff ects from
exposure to chemicals is hampered by our inadequate understanding
of what chemicals people are exposed to and to what degree these
exposures might cause short term (acute) or long term (chronic)
adverse health eff ects.
What is Human Biomonitoring?Human Biomonitoring is the
measurement of toxic substances in the human body. The purpose of
Human Biomonitoring is to determine if you have been exposed to a
toxic substance, how much of that toxic substance is in your body,
and whether the amount of that toxic substance in your body is
enough to cause an adverse health eff ect. Toxic substances
generally enter the body through one of three routes: ingestion,
inhalation, or dermal penetration.
The amount of substance available for toxic action depends on a
number of factors. In most cases, the substance is absorbed to some
degree into the bloodstream where it is distributed throughout the
body. At this point, toxic substances have three possible fates:
they are stored, excreted, or metabolized. Most chemicals undergo
some combination of all three. Storage typically occurs in a
reservoir such as bone or adipose tissue. Excretion involves the
elimination of substances or their metabolites through urine,
feces, saliva, sweat, or exhalation. Substances that are
metabolized are often chemically altered to make excretion of the
substance easier.
The time (antecedent or present), duration, and intensity of
exposure to a particular substance will dictate the choice of human
tissue that is sampled to monitor the substance or its metabolites.
Most Human Biomonitoring involves sampling humans for whole blood
or serum and urine. However, meaningful results have been achieved
from sampling saliva, feces, hair, nails, teeth, breath, and sweat.
For example, when exposed to lead from paint, approximately 90
percent of lead absorbed will be stored in the bone over time and
10 percent is excreted, mostly through the urine, nails, and
hair.
Human Exposure Analysis (Biomonitoring)Why Do Human
Biomonitoring?The goal of Human Biomonitoring is to help prevent
environmental disease by doing the following: Determine which
environmental chemicals actually get into
people Measure how much exposure each person has Assess exposure
for health studies of exposed populations Determine which
population groups are at high risk for exposure
and adverse health eff ects Assess the eff ectiveness of public
health interventions to reduce
exposures Monitor trends in exposure levels over time
EXPOSURE
PARAMETERLogam Arsen (As)
Logam Cadmium (Cd)
Logam Crome (Cr)
Logam Mercury (Hg)
Logam Lead (Pb)
Senyawaan Benzen
Senyawaan Toluene
Senyawaan Xyelene
Senyawaan Acetone
Senyawaan Metyl Etyl Ketone
DETERMINAN
METABOLITUrine
Darah
Urin
Urin and Darah
Darah
Urine
Urin
Urin
Urin
Urin
METHODE
ANALYSISNIOSH
NIOSH
NIOSH
NIOSH
NIOSH
NIOSH
NIOSH
NIOSH
NIOSH
NIOSH
RECOMENDED
VALUESBEI`s ACGIH
BEI`s ACGIH
BEI`s ACGIH
BEI`s ACGIH
BEI`s ACGIH
BEI`s ACGIH
BEI`s ACGIH
BEI`s ACGIH
BEI`s ACGIH
BEI`s ACGIH
What Can AASlab Do for You?AAS Laboratory is uniquely positioned
to help you with a full range of professional services from design,
development, and writing funding/grant proposals to preparing fi
nal consultative reports on sound scientifi c laboratory data.
Please contact +62 21 735 5856 or email :
[email protected] for more information or to schedule a
free initial consultation.
Parameters AnalisisSaat ini AAS Laboratory sudah terakreditasi
ISO 17025 oleh KAN, dengan demikian KETELUSURAN data pengukuran
yang dilakukan dapat terjamin dengan baik. Selain itu, di dukung
peralatan tercanggih di kelasnya seperti GCMS, HPLC dan Atomic
Absorption Spectrophotometer dan Tenaga Ahli yang memang mempunyai
Kompetensi di Bidangnya.
Analisa Biomonitoring yang bisa di lakukan oleh AASLab :
