Chemistry of Functional Organic Chemicals

International Year of Chemistry

– 2011 –

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France-Japan Joint Forum

France-Japan Joint Forum on

Chemistry of Functional Organic Chemicals

for

Celebrating International Year of Chemistry – 2011 –

organized by UDS, CNRS and JSPS

With the support of: Région Alsace

Conseil Général du Bas-Rhin Communauté Urbaine de Strasbourg

Consulat Général du Japon à Strasbourg

Scientific Coordinators: Jean-Pierre Sauvage, Kazuhiko Saigo Organizers : Jean-Marc Planeix, Yoichi Nakatani, Gilberte Chambaud, Régis Réau, Pascal Breuilles

Secretariat: Francine Pinard, Satoko Tada, Bertrand Pinard, Mina Saito

Video of the forum is available on Canal U, the web-TV of French Ministry of Higher Education and Research: http://www.canalc2.tv/

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Timing Schedule Day One – Thursday 23rd June 2011

08:00 Registration Institut de Science et d'Ingénierie Supramoléculaires (ISIS), Université de Strasbourg (UDS)

08:40-09:10

Welcome remarks Chairpersons Jean-Marc Planeix, Yoichi Nakatani - Éric Westhof

Vice-President "Recherche et formation doctorale", University of Strasbourg

- Hiroshi Karube Consul General of Japan in Strasbourg

- Régis Réau Director, Institute of Chemistry, CNRS

- Henri Dreyfus Representative of the Mayor of Strasbourg

- François Loos Vice-President, Conseil Régional d’Alsace

- Kazuhiko Saigo Former Chair, 116th Committee of JSPS Vice-President, Kochi University of Technology

- Motoyuki Ono President, Japan Society for the Promotion of Science (JSPS)

09:10-10:40 1st Session Chairperson: Paolo Samori - Jean-Marie Lehn

“Perspectives in Chemistry: Towards Adaptive Chemistry”

- Masakatsu Shibasaki “Recent Progress in Cooperative Asymmetric Catalysis”

10:40-11:00 Coffee break

11:00-12:30 1st Session Chairperson: Paolo Samori - Clément Sanchez

“Rational Design of Nanostructured and Hierarchically structured Functional Solids”

- Susumu Kitagawa “Gas Science/Technology of Porous Coordination Polymers”

Program

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12:30 Photo session 12:40-13:45 Lunch time ISIS 13:45-15:15 2nd Session Chairperson: Pierre Rabu

- Jean-François Nirengarten “Fullerene-containing nanostructures for materials science and biological applications”

- Masahiko Yamaguchi “Organic Synthesis from Small Helical Molecules towards Materials”

15:15-15:45 Coffee break 15:45-17:15 2nd Session Chairperson: Pierre Rabu

- Wais Hosseini “Controlling movements in molecular turnstiles”

- Takashi Kato “Self-Assembly of Molecular-Based Functional Materials”

Day Two – Friday 24th June 2011 08:00 Registration ISIS 08:30-10:00 3rd Session Chairperson: Pierre Braunstein

- Marc Fontecave “Lessons from Nature: highly selective radical-based chemistry in metabolic and biosynthetic pathways”

- Yoshihisa Inoue “Bio-Supramolecular Photochirogenesis”

10:00-10:20 Coffee break 10:20-11:50 3rd Session Chairperson: Pierre Braunstein

- Mihai Barboiu “Dynamic Interactive Systems – toward natural selection of functions”

- Koji Suzuki “Creation of Sensing Molecules and Materials for Chemical Sensors”

11:50-13:00 Lunch time ISIS 13:00-15:15 4th Session Chairperson: Jean Weiss

- Olivia Reinaud “Biomimetic molecular funnels with hat and boots”

- Norio Teramae “Molecule Recognition Based on Abasic-site-binding Fluorescent Ligands”

- Raymond Ziessel “Boron Dipyrromethene Dyes: A Toolbox for Molecular Photonics and Light Emitting Devices”

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15:15-15:45 Coffee break

15:45-18:00 4th Session Chairperson: Jean Weiss - Yoshiki Chujo

“Mainchain-Type Organoboron Polymers: Synthesis and Photoluminescence Properties”

- Alain Deffieux “Ring Polymers and Related Chain Architectures: Synthesis and Molecular Imaging”

- Takao Ikariya “Greener Molecular Transformation with Bifunctional Molecular Catalysts”

Day Three – Saturday 25th June 2011 07:45 Registration ISIS

08:00-09:30 5th Session Chairperson: Dominique Matt - Didier Astruc

“Green Catalysis inside Dendritic Nanoreactors” - Atsushi Takahara

“Dynamics and Functional Properties of Precisely Designed Polymer Brushes”

09:30-09:45 Coffee break 09:45-11:15 5th Session Chairperson: Dominique Matt

- Régis Réau “Organophosphorus and Organometallic Chemistry for the Design of pi-Conjugated Systems”

- Tamejiro Hiyama “Carbon-Carbon Bond Forming Strategy through C–H and C–C Activation”

11:15-12:00 Special lecture - George M. Whitesides “Charge Transport by Tunneling through Self-Assembled Monolayers (SAMs)”

12:00-12:10 Closing remarks - Jean-Pierre Sauvage - Kazuhiko Saigo - Jean-Marc Planeix - Yoichi Nakatani

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Forum Abstracts and CVs (Speakers)

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1st Session

Perspectives in Chemistry: Towards Adaptive Chemistry Jean-Marie Lehn ISIS, Université de Strasbourg and Collège de France, Paris

Supramolecular chemistry explores the design of systems undergoing self-organization, i.e. systems

capable of generating well-defined functional supramolecular architectures by self-assembly from their

components, thus behaving as programmed chemical systems. Chemistry may therefore be considered as

an information science, the science of informed matter .

The design of molecular information-controlled functional self-organizing systems also provides an original

approach to nanoscience and nanotechnology

Supramolecular chemistry is intrinsically a dynamic chemistry in view of the lability of the interactions

connecting the molecular components of a supramolecular entity and the resulting ability of

supramolecular species to exchange their constituents. The same holds for molecular chemistry when the

molecular entity contains covalent bonds that may form and break reversibility, so as to allow a continuous

change in constitution by reorganization and exchange of building blocks. These features define a

Constitutional Dynamic Chemistry (CDC) on both the molecular and supramolecular levels.

CDC takes advantage of dynamic constitutional diversity to allow variation and selection in response to

either internal or external factors to achieve adaptation.

The merging of the features: - information and programmability, - dynamics and reversibility, -constitution

and structural diversity, points towards the emergence of adaptive and evolutive chemistry.

Lehn, J.-M., Supramolecular Chemistry: Concepts and Perspectives, VCH Weinheim, 1995. Lehn, J.-M., Toward complex matter: Supramolecular chemistry and self-organization, Proc. Natl. Acad. Sci. USA, 2002, 99, 4763. Lehn, J.-M., From supramolecular chemistry towards constitutional dynamic chemistry and adaptive chemistry, Chem. Soc. Rev., 2007, 36, 151.

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Jean-Marie Lehn Professor ISIS – Université de Strasbourg Address: 8, allee Gaspard Monge, 67000 Strasbourg, France Phone: +33 (0)3 68 85 51 45 /44 Fax: 33 (0)3 68 85 51 40 E-mail: lehn@unistra.fr http://www-isis.u-strasbg.fr

Jean-Marie LEHN was born in Rosheim, France in 1939. In 1970 he became Professor of Chemistry at the

Université Louis Pasteur in Strasbourg and from 1979 to 2010 he was Professor at the Collège de France

in Paris. He is presently Professor Emeritus at the University of Strasbourg. He shared the Nobel Prize in

Chemistry in 1987 for his studies on the chemical basis of “molecular recognition” (i.e. the way in which a

receptor molecule recognizes and selectively binds a substrate), which also plays a fundamental role in

biological processes.

Over the years his work led him to the definition of a new field of chemistry, which he has proposed calling

“supramolecular chemistry” as it deals with the complex entities formed by the association of two or more

chemical species held together by non-covalent intermolecular forces, whereas molecular chemistry

concerns the entities constructed from atoms linked by covalent bonds. Subsequently, the area developed

into the chemistry of "self-organization" processes and more recently towards "adaptive chemistry".

Author of more than 850 scientific publications, Lehn is a member of many academies and institutions. He

has received numerous international honours and awards.

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1st Session

Recent Progress in Cooperative Asymmetric Catalysis Masakatsu Shibasaki Institute of Microbial Chemistry, Tokyo

We have been very much interested in highly atom economical asymmetric catalysis, that is, catalytic

asymmetric induction just through proton transfer conditions. To realize asymmetric catalysis of this type,

we believe that asymmetric two-center catalysis or cooperative asymmetric catalysis plays a key role.

In this symposium, practical catalytic asymmetric synthesis of ranirestat (a highly potent aldose reductase

inhibitor under clinical development for the treatment of diabetic complications), α β3-3-adrenoreceptor

agonist, R207910 (a promising potent antitubeculosis drug candidate of both drug-sensitive and

drug-resistant Mycobacterium tubeculosis), and development of direct catalytic asymmetric aldol reaction

of thioamides is presented.

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Masakatsu Shibasaki Director: Institute of Microbial Chemistry Emeritus Professor: The University of Tokyo & Hokkaido University Address: 3-14-23, Kamiosaki, Shinagawa-ku, Tokyo, 141-0021, Japan Phone: +81 (0)3 34 47 77 79 Fax: +81 (0)3 34 41 75 89 E-mail: mshibasa@bikaken.or.jp http://www.bikaken.or.jp/research/group/shibasaki/shibasaki- lab/index.html

Masakatsu Shibasaki was born in 1947 in Saitama, Japan, and received his PhD. from the University of

Tokyo in 1974 under the direction of the late Professor Shun-ichi Yamada before doing postdoctoral studies

with Professor E. J. Corey at Harvard University. In 1977 he returned to Japan and joined Teikyo

University as an associate professor. In 1983 he moved to Sagami Chemical Research Center as a group

leader, and in 1986 took up a professorship at Hokkaido University, before returning to the University of

Tokyo as a professor in 1991. He was a visiting professor at Philipps-Universität Marburg during 1995. He

has received the Pharmaceutical Society of Japan Award for Young scientists (1981), Inoue Prize for

Science (1994), Fluka Prize (Reagent of the Year, 1996), the Elsevier Award for Inventiveness in Organic

Chemistry (1998), the Pharmaceutical Society of Japan Award (1999), the Molecular Chirality Award

(1999), the Naito Foundation Research Prize for 2001 (2002), ACS Award (Arthur C. Cope Senior Scholar

Award) (2002), the National Prize of Purple Ribbon (2003), the Toray Science Award (2004), The Japan

Academy Prize (2005), Takamine Memorial Sankyo Award (2006), the Rare Earth Society of Japan Award

(2007), ACS Award (Creative Work in Synthetic Organic Chemistry (2008), Centenary Medal and

Lectureship Award (Royal Society of Chemistry) and Prelog Medal (ETH, Switzerland) in 2008 and many

others.

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1st Session

Rational Design of Nanostructured and Hierarchically structured Functional Solids Clément Sanchez Laboratoire de Chimie de la Matière Condensée de Paris, CNRS, Université Pierre et Marie Curie. Collège de France

Hybrid inorganic-organic materials can be broadly defined as synthetic materials with organic and

inorganic components which are intimately mixed. They can be either homogeneous systems derived from

monomers and miscible organic and inorganic components, or heterogeneous and phase-separated

systems where at least one of the components’ domains has a dimension ranging from a few Å to several

nanometers. Hybrid phases can also be used to nanostructure or texture new inorganic nanomaterials

(porous or non porous). Research on hybrids has experienced an explosive growth since the 1980s, with

the expansion of soft inorganic chemistry processes. The mild synthetic conditions provided by the sol-gel

process such as metallo-organic precursors, low processing temperatures and the versatility of the

colloidal state allow for the mixing of the organic and inorganic components at the nanometer scale in

virtually any ratio. These features, and the advancement of organometallic chemistry and polymer and

sol-gel processing, make possible a high degree of control over both composition and structure (including

nanostructure) of these materials, which present tunable structure-property relationships. This, in turn,

makes it possible to tailor and fine-tune properties (mechanical, optical, electronic, thermal, chemical…) in

very broad ranges, and to design specific systems for applications. Hybrid materials can be processed as

gels, monoliths, thin films, fibers, particles or powders or can be intermediates to design materials having

complex shapes or hierarchical structures. The seemingly unlimited variety, unique structure-property

control, and the compositional and shaping flexibility give these materials a high potential. Indeed, some

hybrid materials are already commercial. This keynote lecture will describe some recent advances on the

Chemistry and processing of Nanostructured and Hierarchically structured Functional Inorganic and

hybrid Solids. Some of their properties will also be discussed.

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Clément Sanchez Laboratoire de Chimie de la Matière Condensée de Paris, CNRS, Université Pierre et Marie Curie. Collège de France Address: 11 Place Marcelin Berthelot, Bâtiment D. 75231, Paris, France Phone: +33 (0)1 44 27 15 01 Fax: 33 (0)1 44 27 15 04 E-mail: clement.sanchez@upmc.fr http://www.labos.upmc.fr/lcmcp/?q=node/1973

Clément Sanchez Professor at the Collège de France (Chaire de Chimie des Matériaux Hybrides”), leads

the Laboratory Chimie de la Matière Condensee of Paris at the University of Paris VI. Ph.D at the University

of Paris VI in 1981, he did post-doctoral work at the University of Berkeley. Today, he currently leads a

research group working on sol-gel chemistry and physical properties of nanostructured porous and

non-porous inorganic and hybrid organic–inorganic materials shaped as monoliths, microspheres and films.

Targetted application domains include: chemical and biological sensors, photovoltaics, catalysis nad

photocatalysis, fuel cells, and new hybrid therapeutic vectors. He has co-authored more than 400 articles

and book chapters and he has more than 50 patents. Member of the French and European Academies,

he was awarded by many scientific French and International prizes.

(more information at: http://www.labos.upmc.fr/lcmcp/?q=node/1973)

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1st Session Gas Science/Technology of Porous Coordination Polymers Susumu Kitagawa Institute for Integrated Cell-Material Sciences, Department of Synthetic Chemistry and Biological Chemistry, Kyoto University

The recent advent of porous coordination polymers (PCPs) or metal-organic frameworks (MOFs) as new

functional microporous materials, have attracted the attention of chemists and physicists due to not only

scientific but also application interest in the creation of unprecedented regular nano-sized spaces and in the

finding of novel phenomena. We have found flexible porous frameworks, which respond to specific guests,

dissimilar to the conventional porous materials. We call this new material as “soft porous crystal (SPC)”.

SPCs provide nanopores responsive to gas species, showing unique properties ranging optical to magnetic

properties. They also afford efficient reaction vessels, which allow the conversion of occluded guests, the

typical instances are controlled living radical polymerization of styrens and stereoregulated polymerization

of substituted acetylenes. We are focusing on separation/storage/conversion of various gases such as

CO2,NO,CO and CH4, toward a new technology of gases including air. The key for success is to develop

porous coordination polymers or metal-organic frameworks.

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Susumu Kitagawa Institute for Integrated Cell-Material Sciences Department of Synthetic Chemistry and Biological Chemistry, Kyoto University Address: Katsura, Nishikyo-ku, Kyoto, 615-8510, Japan Phone : +81 (0)7 53 83 27 33 FAX: +81 (0)7 53 83 27 32 E-mail: kitagawa@icems.kyoto-u.ac.jp http://www.sbchem.kyoto-u.ac.jp/kitagawa-lab/index.htm http://kip.jst.go.jp/

Date of birth: July 4, 1951 Title: Deputy Director

Professor, Dr. Eng. Education: 1975-1979 Kyoto University, Graduate School, Hydrocarbon Chemistry, PhD degree

1971-1974 Kyoto University, Undergraduate course, Hydrocarbon Chemistry

Professional Appointments: 2007-present Deputy Director, Institute for Integrated Cell-Material Sciences, Kyoto University

1998-present Professor, Kyoto University, Department of Synthetic Chemistry & Biological Chemistry

1992-1998 Professor, Tokyo Metropolitan University, Department of Chemistry

1988-1992 Associate Professor, Kinki University, Department of Chemistry

1986-1987 Visiting Scientist, Department of Chemistry, Texas A & M University

F. A. Cotton Laboratory

1983-1988 Lecturer, Kinki University, Department of Chemistry

1979-1983 Assistant Professor, Kinki University, Department of Chemistry

Award: 2011 Research Category, The Commendation for Science and Technology by the Minister of

Education, Culture, Sports, Science and Technology

2010 Thomson Reuters Citation Laureate (Chemistry)

2009 The Chemical Society of Japan Award, Japan

2008 Humboldt Research Award, Germany

2007 The Japan Society of Coordination Chemistry Award, Japan

2007 Earl L. Muetterties Memorial Lectureship, University of California, Berkeley

2002 The Chemical Society of Japan Award for Creative Work, Japan

Research interests: Coordination Chemistry, Porous Materials

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2nd Session

Fullerene-containing nanostructures for materials science and biological applications Jean-François Nierengarten Laboratoire de Chimie des Matériaux Moléculaires, Université de Strasbourg et CNRS, Ecole Européenne de Chimie, Polymères et Matériaux (ECPM)

Carbon rich nanostructures have been a major hot topic in chemical research over the past two decades.

In particular, fullerenes combining three-dimensionality with unique electronic properties are extremely

promising nanostructures for the preparation of new advanced materials or biologically active molecules.1

As part of this research, our group has been involved in the development of fullerene-based photoactive

molecular devices for fundamental photophysical investigations but also for applications in solar energy

conversion.2 On the other hand, our group has also developed a large variety of fullerene-containing

dendrimers for various applications in supramolecular chemistry and materials science.3 More recently, we

have started a research program on fullerene hexakis-adducts with a Th-symmetrical octahedral addition

pattern.4 The spherical framework of such fullerene derivatives is indeed an appealing plateform for the

preparation of new nanomaterials and bioactive molecules. The most recent advances in this particular

field will be presented to illustrate the current state-of-the-art of fullerene chemistry for the

development of new functional nanostructures. 1. Fullerenes: Principles and Applications; F. Langa, J.-F. Nierengarten (Eds.), RSC Nanoscience and Nanotechnology Series,

2007.

2. For reviews, see: J.-F. Nierengarten, New J. Chem. 2004, 28, 1177; T. M. Figueira-Duarte, A. Gégout, J.-F. Nierengarten, Chem.

Commun. 2007, 109.

3. For reviews, see: J.-F. Nierengarten, Topics in Current Chemistry 2003, 228, 87; U. Hahn, F. Cardinali, J.-F. Nierengarten, New

J. Chem. 2007, 31, 1128.

4. J. Iehl, J.-F. Nierengarten, Chem. Eur. J. 2009, 15, 7306; J. Iehl, J.-F. Nierengarten, Chem. Commun. 2010, 46, 4160; P.

Compain, C. Decroocq, J. Iehl, M. Holler, D. Hazelard, T. Mena Barragán, C. Ortiz Mellet, J.-F. Nierengarten, Angew. Chem. Int. Ed.

2010, 49, 5753; P. Fortgang, E. Maisonhaute, C. Amatore, B. Delavaux-Nicot, J. Iehl, J.-F. Nierengarten, Angew. Chem. Int. Ed.

2011, 50, 2364; S. Cecioni, V. Oerthel, J. Iehl, M. Holler, D. Goyard, J.-P. Praly, A. Imberty, J.-F. Nierengarten, S. Vidal, Chem. Eur.

J. 2011, 17, 3252.

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Jean-François Nierengarten Laboratoire de Chimie des Matériaux Moléculaires, Université de Strasbourg et CNRS, Ecole Européenne de Chimie, Polymères et Matériaux (ECPM) Address: 25 rue Becquerel, 67087 Strasbourg, Cedex 2, France Phone : +33 (0)3 68 85 27 64 FAX: +33 (0)3 68 85 27 74 E-mail: nierengarten@chimie.u-strasbg.fr http://www-ecpm.u-strasbg.fr/umr7509/WebLaboNierengarten.htm

Jean-François Nierengarten studied Biochemistry and Chemistry at the University of Strasbourg, France,

and received his doctoral degree under the supervision of J.-P. Sauvage and C. Dietrich-Buchecker

(Strasbourg, 1994). After postdoctoral work with F. Diederich at the ETH-Zürich, Switzerland, during

1994-1996, he returned to Strasbourg as a CNRS researcher. In 2005, he moved to the Laboratoire de

Chimie de Coordination (LCC) in Toulouse. Since 2007, he is head of the Laboratoire de Chimie des

Matériaux Moléculaires (University of Strasbourg). Jean-François Nierengarten is involved in the synthetic

chemistry of the fullerenes since 1995 and is author of more than 200 papers, review articles and book

chapters. The expertise of his group ranges from the development of new synthetic methodologies to the

preparation of compounds having the required design features for their applications.

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2nd Session Organic Synthesis from Small Helical Molecules towards Materials Masahiko Yamaguchi Advanced Institute for Materials Research (WPI-AIMR), Department of Organic Chemistry, Graduate School of Pharmaceutical Sciences, Department of Chemistry, Graduate School of Science, Tohoku University

Synthetic organic molecules with molecular weight of several to tens of thousands can exhibit different

properties, like DNA or protein, from usual organic molecules of molecular weight several hundreds.

Built-up macromolecules are such nanometer size molecules with defined structure, and are synthesized

by the methodology of organic synthesis.

We considered that systematic study on a diversity of built-up macromolecules can lead to the

development of novel structures and function. The studies will broaden and deepen our understanding on

the principles, which govern the properties of nanometer size molecules. As an example, we describe

synthesis and property of chiral oligomeric compounds containing helicene. They form double-helixes in

solution, which switch its structure between random-coil like DNA. Molecular systems containing the

helicene-contaning built-up macromolecules are also studied on the solid surfaces and in the gels.

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Masahiko Yamaguchi Professor Advanced Institute for Materials Research (WPI-AIMR) Department of Organic Chemistry, Graduate School of Pharmaceutical Sciences Department of Chemistry, Graduate School of Science, Tohoku University Address: Sendai 980-8578, Japan Phone : +81 (0)2 27 95 68 12 FAX: +81 (0)2 27 95 68 11 E-mail: yama@mail.pharm.tohoku.ac.jp http://iremc.pharm.tohoku.ac.jp/ http://www.pharm.tohoku.ac.jp/~sekkei/sekkei-j.html

Masahiko Yamaguchi received his BSc (1977) and PhD degrees (1982) from the University of Tokyo under

guidance of Professor T. Mukaiyama. He joined Kyushu Institute of Technology in 1982 as Assistant

Professor and was promoted to Associate Professor in 1985. During 1987 to 1988 he worked as a post

doctorate fellow at Yale University with Professor S. Danishefsky. He moved to the Department of

Chemistry at Tohoku University in 1991. In 1997, he was appointed Professor in the Faculty of

Pharmaceutical Sciences of Tohoku University. He became Professor of Graduate School of

Pharmaceutical Sciences and Graduate School of Science of the same university in 2006, and Professor of

WPI-AIMR in 2007. Since 2007, he is group leader of GCOE program for chemistry in Tohoku University.

He received the Chemical Society of Japan Award for Young Chemists in 1986 and the Synthetic Organic

Chemistry Award, Japan in 2007.

Research interest

1) Transition metal catalysed synthesis of organosulfur and organophosphorus compounds

2) Synthesis and property of helicenes

3) Synthesis and property of built-up macromolecules

4) Development of organic materials and biomaterials

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2nd Session Controlling movements in molecular turnstiles Wais Hosseini Université de Strasbourg, Institut Le Bel, UMR CNRS 7140, Tectonique Moléculaire du Solide

Movement plays a fundamental role in the living world. Biological motors of the linear type based on

myosine1 or kinesine2 and rotary motors3 based on ATPase have been discovered and studied.

An abiotic motor is a molecular architecture for which controlled (speed, amplitude and orientation)

movements (translational or rotational) between a fixed and a mobile portion may be induced by external

stimuli.4

As a first step towards molecular motors, a series of molecular turnstiles based on a porphyrin core as a

stator bearing specific interactions sites, a hinge (octahedral Sn(IV) cation) located at the centre of the

porphyrin and different handles equipped with recognition sites connected to the porphyrin through Sn-O

axial bonds have been designed.5-7 The, synthesis and structural characterisation, both in solution

by 1H-NMR and in the solid state by X-ray diffraction on single crystals, of a series of molecular turnestils will

be presented.

1 J. T. Finer, R. M. Simmons, J. A. Spudlich, Nature 1994, 368, 113; 2 M. Whittaker, E. M. Wilson-Kubalek, J. E. Smith, L. Faust, R. A. Milligan, H. L. Sweeney, Nature 1995, 378, 748.

2 E. P. Sabin, F. J. Kull, R. Cook, R. D. Vale, R. J. Fletterick, Nature 1996, 380, 555; E. Meuhöfer, J. Howard, Proc. Natl. Acad. Sci. U.S.A., 1995, 92, 574.

3 T. Elston, H. Wang, G. Oster, Nature 1998 391, 510; H. Noji, R. Yasuda, M. Yoshida, K. Kinosita Jr., Nature 1997, 386, 299. 4 J.-P. Sauvage, Science, 2001, 291, 2105; J. P. Sauvage, Acc. Chem. Res. 1998, 31, 611; J.-P. Collin, J.-M. Kern, L. Raehm,

J.-P. Sauvage, in Molecular Switches, Editor: Feringa, Ben L, Wiley-VCH Verlag GmbH, Weinheim, Germany, 2001, 249; V. Balzani, M. Gomez-Lopez, J. F. Stoddart, Acc. Chem. Res. 1998, 31, 405; J. F. Stoddart, Acc. Chem. Res, 2001, 34, 410; N. Koumura, R. W. J. Zijlstra, R. A. van Delden, N. Harada, B. L. Feringa, Nature 1999, 401, 152; M. K. J. Ter Wiel, R. A. Van Delden, A. Meetsma, B. L. Feringa, J. Am. Chem. Soc., 2005, 127, 14208; W. R. Browne, B. L. Feringa, Nature Nanotechnology, 2006, 1, 25; E. R. Kay, D. A. Leigh, F. Zerbetto, Angew. Chem. Int. Ed, 2007, 46, 72.

5 A. Guenet, A.; E. Graf; N. Kyritsakas; L. Allouche; M. W. Hosseini, Chem. Commun., 2007, 2935. 6 A. Guenet, E. Graf, N. Kyritsakas, M. W. Hosseini, Inorg Chem., 2010, 49, 1872. 7 T. Lang, A. Guenet, E. Graf, N. Kyritsakas, M. W. Hosseini, Chem. Commun., 2010, 46, 3508. 8 A. Guenet, E. Graf, N. Kyritsakas, M. W. Hosseini, Chemistry, 2011 ASAP. 9 T. Lang, E. Graf, N. Kyritsakas, M. W. Hosseini, Dalton Trans., 2011, 40, 3517-3523.

10 T. Lang, E. Graf, N. Kyritsakas, M. W. Hosseini, Dalton Trans., 2011 DOI: 10.1039/c1dt10184f.

Schematic representation of the open (a), three closed

states (b), (c) and (d) of a molecular turnstile composed

of a stator equipped with a hinge (light blue) bearing two

different (blue and red) interaction sites (e and f) and two

handles based on a tridentate coordination pole (purple)

and of its metal complex. The green sphere represents a

metal with square planar coordination geometry. The

circle with a red sphere represents a competitive

protected metal complex.

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Wais Hosseini Professor FRSC Institut Universitaire de France (IUF) Chaire de Tectonique Moléculaire International Center for Frontier Research in Chemistry (FRC) Editor-in-Chief of New Journal of Chemistry (NJC) http://www.rsc.org/Publishing/Journals/nj/index.asp Address: 4, rue Blaise Pascal, CS 90032, 67081 Strasbourg Cedex, France Phone : +33 (0)3 68 85 13 23 FAX: +33 (0)3 68 85 13 25 E-mail: hosseini@unistra.fr http://www-chimie.u-strasbg.fr/%7Elcco/perso/Wais/index_fr.html

Mir Wais Hosseini was born in Kabul, Afghanistan and moved to Strasbourg at the age of 17. He was

educated at the University Louis Pasteur, Strasbourg. He started his research career under the supervision

of Jean-Marie Lehn and worked with him for 10 years as a CNRS researcher. After a post-doctoral period

with K. Raymond at Berkeley, he became a full professor at University Louis Pasteur in 1990 and created

his own research group. Currently, he is an Exceptional Class Professor at the University of Strasbourg and

a Senior member of the prestigious Intitut Universitaire de France (IUF) where he occupies the Chair of

Molecular Tectonics. He is a fellow of the Royal Society of Chemistry and member of Academia Europae.

His scientific career may be divided into two periods. The first part (1979-90) was with Jean-Marie Lehn.

While at that time the vast majority of supramolecular chemists were exclusively working on cation

recognition, he worked on anion recognition and on supramolecular catalysis. During his period at Berkeley,

he worked on abiotic analogues of siderophores. During his second period, he started a new area of

research centered on molecular tectonics, an approach bridging the gap between supramolecular

chemistry, solid state chemistry, materials science and self-assembly. Combining molecular and

supramolecular synthesis, he explored, in parallel, the use of the majority of possible attractive

intermolecular forces for the design of molecular networks and crystals.

He as supervised 34 PhD students, 5 "Habilitations", 10 postdoctoral fellows and ca 80 undergraduate

students. He published over 255 manuscripts and delivered some 350 lectures. He was invited Professor at

University of Geneva, University of Western Australia, Tsukuba Research Centre, University of Tokyo,

Academia Sinica and University of Kyoto. He contributed to scientific edition as Scientific Editor of Chemical

Communications and more recently as the Editor-In-Chief of New Journal of Chemistry.

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2nd Session Self-Assembly of Molecular-Based Functional Materials Takashi Kato Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo

Control of self-organized structures of molecular assemblies is a useful approach to the fabrication of highly functional molecular materials [1-3]. Enhanced and low-dimensional dynamic functions can be induced by the incorporation of ion-, electro-, photo-active moieties into self-organized liquid crystalline (LC) assemblies. Herein we describe our recent approaches to the development of functional supramolecular LC assemblies: (a) Nanosegregated LC structures can be used as pathways for ion transportation. One-, two, and three-dimensional ion-transporting channels have been formed in the nanostructured LC phases through self-organization of ionic molecules and lithium salts [1]. (b) New electrochromic liquid crystals have been built through the control of nanosegregated structures for electron and ion transportation [2]. Oligothiophenes bearing imidazolium moieties exhibit electrochromic responses in the bulk smectic LC phases without electrolytes. (c) Dynamically functional photo-functional materials, mechano-responsive luminescent liquid crystals have been developed [3]. Once mechanical shear force is applied to these pi-conjugated LC molecules, the emission colours are changed due to mechano-induced liquid crystal phase transitions. References: [1] Angew Chem. Int Ed (2006) 45, 38; (2010) 49, 7847. J Am Chem Soc (2011) 133, 2163. [2] J Am Chem Soc (2010) 132, 7702. [3] Nature Chem (2009) 1, 605.

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Takashi Kato Professor Department of Chemistry and Biotechnology, School of Engineering The University of Tokyo Address: Bunkyo-ku Tokyo 113-8656, JAPAN Phone : +81 (0) 3 58 41 74 40 FAX: +81 (0) 3 58 41 86 61 E-mail: kato@chiral.t.u-tokyo.ac.jp http://kato.t.u-tokyo.ac.jp/index-e.html

Takashi Kato is a professor at Department of Chemistry and Biotechnology, School of Engineering, the

University of Tokyo since 2000. He received his Ph.D. degree at the University of Tokyo under supervision

of Professor Toshiyuki Uryu in 1988. After his postdoctoral research at Cornell University with Professor

Jean M. J. Frechet, he joined the University of Tokyo. His research focuses on self-assembled functional

materials including supramolecular liquid crystals, ion- and electron-active materials, liquid-crystalline gels,

functional polymers, and organic/inorganic hybrids. He is the recipient of several awards including the

Chemical Society of Japan Award for Young Chemists (1993), The Wiley Polymer Science Award

(Chemistry) 2001, the 17th IBM Japan Science Award (2003), the 1st JSPS Prize (2005), the Award of

Japanese Liquid Crystal Society (2008), the Award of the Society of the Polymer Science, Japan (2010).

He has published about 340 papers including original papers, reviews, and chapters of books. He is editors

of "Polymer Journal", and "Chemistry Letters", advisory boards of "Journal of Materials Chemistry" and

"Advanced Materials", "Chemical Science", "The Chemical Records". He is currently a board of director of

the international liquid crystalline society.

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3rd Session Lessons from Nature: highly selective radical-based chemistry in metabolic and biosynthetic pathways Marc Fontecave Laboratoire de Chimie et Biologie des Métaux, UMR CNRS-CEA-Université Joseph Fourier 5249, CEA Grenoble, Collège de France,

Free radicals are generally considered as highly reactive and toxic species within living organisms and biological scavengers provide them with protection. However, recent discoveries have shown that a large number of biochemical reactions proceed through radical mechanisms with free radical intermediates allowing very selective substrate activation and transformation. Radical-SAM enzymes constitute a very large family of iron sulphur proteins involved in a great variety of metabolic pathways and biosynthetic reactions. The active site, a complex between a [4Fe-4S] cluster and S-adenosylmethionine (SAM), serves to generate free radicals for reaction initiation. This unique and complex radical chemistry will be specifically illustrated through examples of enzymes involved in selective modification of nucleic acids and proteins. First, ribonucleotide reductase, involved in deoxyribonucleotide synthesis, will be presented as a prototype of this class of enzymes (1). Second, mechanistic studies of the sporephotoproduct lyase, an enzyme essential for repairing DNA in pathogenic sporulating bacteria exposed to UV radiation, will be discussed (2,3). Third, enzymes participating in the biosynthesis of sulfur-containing compounds and catalyzing C-H to C-S bond formation, will be presented with special emphasis on thiomethyl-transferases (4,5,6,7).

(1) Deoxyribonucleotide synthesis in anaerobic microorganisms : the class III ribonucleotide reductase. M. Fontecave, E. Mulliez, D. Logan. Progress in Nucleic Acid Research and Molecular Biology 2002, 72, 95-127; (2) DNA repair and free radicals: New insights into the mechanism of spore photoproduct lyase revealed by single mutation. A. Chandor-Proust, O. Berteau, T. Douki, D. Gasparutto, S. Ollagnier-de-Choudens, M. Atta, M. Fontecave. J. Biol. Chem. 2008, 283, 36361-36368; (3) Combined NMR and DFT studies for the absolute configuration elucidation of the spore photoproduct, a UV-induced DNA lesion. C. Mantel, A. Chandor, D. Gasparutto, T. Douki, M. Atta, M. Fontecave, P-A. Bayle, J-M. Mouesca, M. Bardet. J. Am. Chem. Soc. 2008, 130, 16978-16984; (4) Biological radical sulfur insertion reactions. M. Fontecave, S. Ollagnier-de Choudens, E. Mulliez, Chem. Rev. 2003, 103,2149-2166; (5) MiaB, a bifunctional Radical-S-adenosylmethionine enzyme involved in the thiolation and methylation of tRNA, contains two essential [4Fe-4S] clusters. H. L. Hernández, F. Pierrel, E. Elleingand, R. García-Serres, Boi Hanh Huynh, M. K. Johnson, M. Fontecave, M. Atta. Biochemistry 2007, 46, 5140-5147; (6) Identification of eukaryotic and prokaryotic methythiotransferases for biosynthesis of 2-methylthio-N6threonylcarbamoyladenosine in tRNA. S. Arragain, SK. Handelman, F. Forouhar, FY. Wei, K. Tomizawa, JF. Hunt, T. Douki, M. Fontecave, E. Mulliez, M. Atta. J. Biol. Chem. 2010, 285, 28425-28433; (7) Post-translational modification of ribosomal proteins: Structural and functional characterization of RimO from Thermotoga maritima, a Radical-SAM methylthiotransferase. S. Arragain, R. Garcia-Serres, G. Blondin, T. Douki, M. Clemancey, J.-M.Latour, F. Forouhar, H. Neely, G.T. Montelione, J.F. Hunt, E. Mulliez, M. Fontecave, M. Atta. J. Biol. Chem. 2010, 285, 5792-5801

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Marc Fontecave Professor at the College de France, Paris Member of the French Academy of Sciences President of the Scientific Council of Paris Laboratoire de Chimie et Biologie des Métaux, UMR5249 CEA Grenoble Address: CEA Grenoble, 17 Avenue des Martyrs, 38054 Grenoble Cedex 9 Collège de France, 11 Place Marcelin Berthelot, 75231 Paris Cedex 05, France Phone : +33 (0)4 38 78 91 22 (sec:9102) E-mail: mfontecave@cea.fr http://www.college-de-france.fr/default/EN/all/chi_pro/index.htm

27/09/1956 Married, 3 children 1984: PhD in Chemistry 1985-1986: Post-doc, Karolinska Institute 1988-2008: Professor, University J. Fourier, Grenoble 1995-1998 : Director of the Doctoral School “Chemistry-Biology” of the University of Grenoble 1997-2006: Director of the Laboratory of Chemistry and Biochemistry of Biological

Redox Centers, CEA Grenoble 2007-2010: Director of the Laboratory of Chemistry and Biology of Metals, CEA Grenoble 2003-2008: Director of the Institute of Research in Life sciences and Technologies CEA-Grenoble 2003-2006: Director of the Institute of Metals in Biology of Grenoble (IMBG) Distinctions 1992-1996 : Member of the Institut Universitaire de France (Junior) 2004 : Silver Medal of the CNRS (Centre National de la Recherche Scientifique) 2005-2008 : Member of the Institut Universitaire de France (Senior) 2006 : Election at the French Academy of Sciences 2008: Nominated as Professor at the College de France

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3rd Session

Bio-Supramolecular Photochirogenesis Yoshihisa Inoue Department of Applied Chemistry, Osaka University

Photochirogenesis, or chiral photochemistry, is one of the most intriguing topics in current chemistry, as an

attractive alternative to the conventional catalytic and enzymatic asymmetric syntheses which met a great

success in the last few decades.

Photochemical asymmetric synthesis can be achieved by using a variety of chiral molecular sensitizers

and hydrogen-bonding templates as well as chiral supramolecular and biomolecular hosts. Of these

photochirogenesis strategies, the supramolecular approach is of particular interest, enabling us to execute

the dual stereocontrol through the pre-organization of prochiral reactant molecule(s) in the ground state

and also through the manipulation of subsequent chirogenic reactions in the excited state.

Serum albumins possess binding pockets for various endogenous and exogenous organic compounds,

providing ideal chiral environment for supramolecular photochirogenesis. We employed a variety of

mammalian serum albumins as biomolecular hosts for mediating the enantiodifferentiating

photocyclodimerization of 2-anthracenecarboxylate to obtain chiral photocyclodimers in >90% ee.

More recently, we used molecular chaperone prefoldin and its subunits as biomolecular hosts for the same

photochirogenic reaction and elucidated the binding and photocyclodimerization mechanisms.

A global view of the bio-supramolecular photochirogenesis will be discussed in the lecture.

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Yoshihisa Inoue Professor of Chemistry Department of Applied Chemistry, Osaka University Address: 2-1 Yamada-oka, Suita 565-0871, Japan Phone : +81 (0) 6 68 79 79 20 FAX: +81 (0) 6 68 79 79 23 E-mail: inoue@chem.eng.osaka-u.ac.jp http://www.chem.eng.osaka-u.ac.jp/~inoken/

Degrees

Bachelor (Chemistry) 1972 Osaka University Master (Chemistry) 1974 Osaka University Ph.D. (Chemistry) 1977 Osaka University

Positions Assistant Professor 1977-85 Himeji Institute of Technology Research Associate 1978-79 Columbia University (Prof. N.J. Turro) Associate Professor 1985-94 Himeji Institute of Technology Professor 1994--date Osaka University Director 1996-2002 Inoue Photochirogenesis Project (ERATO, JST) Director 2002-2008 Entropy Control Project (ICORP, JST)

Research Interest Chiral Photochemistry; Supramolecular Chemistry

Honors CSJ Award for Young Chemists 1983 Chemical Society of Japan JPA Award 1998 Japanese Photochemistry Association Molecular Chirality Award 2003 Molecular Chirality Research Organization CUSO Lectureship Award 2007 Conference Universitaire de Suisse Occidentale JPA Lectureship Award 2009 Japanese Photochemistry Association Humboldt Research Award 2011 Alexander von Humboldt Foundation

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3rd Session Dynamic Interactive Systems – toward natural selection of functions Mihail Barboiu Institut Europeen des Membranes, Adaptive Supramolecular Nanosystems Group ENSCM/UMII/UMR CNRS 5635

Dynamic interactive systems are defined by networks of exchanging and reversibly connected objects (supermolecules, polymers, biomolecules, biopolymers, pores, nanoplatforms, surfaces, liposomes, cells). They operate under natural selection to allow spatial/temporal and structural/functional adaptability in response to internal constitutional or to external stimulant factors. Herein we will discuss some selected examples of hybrid organic/inorganic systems materials (SYSMAT), covering (a) the sol–gel resolution of constitutional architectures from dynamic combinatorial libraries and (b) the generation of dynamic hybrid materials and systems membranes (SYSMEM) able to evolve inside pore functional architectures via ionic stimuli, so as to improve membrane transport functions.

1. M. Barboiu, Chem. Commun., 2010, 46, 7466-7476. 2. M. Barboiu, S. Cerneaux, G. Vaughan, A. van der Lee, J. Am. Chem. Soc. 2004, 126, 3545-3550 3. C. Arnal-Herault, M. Michau, M. Barboiu, Angew. Chem. Int. Ed. 2007, 46, 8409-8413. 4. C. Arnal-Hérault, M. Barboiu, A. Pasc, M. Michau, A. van der Lee, Chem. Eur. J. 2007, 13, 6792 5. C. Arnal-Herault, A. Pasc-Banu, M. Barboiu, Angew. Chem. Int. Ed. 2007, 46, 4268-4272.

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Mihail Barboiu Institut Europeen des Membranes Adaptive Supramolecular Nanosystems Group ENSCM/UMII/UMR CNRS 5635 Address: Place Eugene Bataillon CC047, 34095, Montpellier, France Phone : +33 (0)4 67 14 91 95 FAX: +33 (0)4 67 14 91 19 E-mail: mihai.barboiu@iemm.univ-montp2.fr http://www-en.iemm.univ-montp2.fr/spip.php?rubrique12

Mihail Barboiu received his PhD in 1998 from University of Montpellier II before spending 2 years as Associate Professor at College de France, with Prof. Jean-Marie LEHN at the Supramolecular Chemistry Laboratory, at University Louis Pasteur, Strasbourg. Since 2001, he has been CNRS Research Fellow and then Group Leader/Senior Researcher at the Institut Européen des Membranes in Montpellier, France and Associate Professor at University Politehnica of Bucharest, Romania. A major focus of his research is Dynamic Constitutional Chemistry of functional adaptive systems: biomimetic membranes, biosensors, etc. Authors of more than 130 scientific publications, Dr. Barboiu has received in 2004 EURYI Award in Chemistry.

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3rd Session

Creation of Sensing Molecules and Materials for Chemical Sensors Koji Suzuki Department of Applied Chemistry, Keio University

In the biological field, chemical sensors such as synthetic molecular probes play an important role in the

investigation of biological functions, and in cellular or in vivo imaging. The creation of original molecular

probes is one of the main concerns in our research group. In the past, designed ion sensing ligands

(ionophores) have been successfully synthesized and are now in practical use in biomedical electrolyte

analysis. One of our recent research was the creation of imaging probes based on our ionophore design

concept and our developed bright fluorescent molecules (KMG series dyes). By linking an ion recognizing

ionophore with a fluorescent dye as a transducer, a chemical probe (fluorescent probe) is obtained,

transforming a simple molecular recognition ligand into a sensor ligand. For instance, a KFL fluorescent

dye combined with a BAPTA chelating group resulted in a fluorescent probe for calcium ions. In this case,

the introduction of a suitable linker connecting the KFL dye moiety and the BAPTA chelating moiety

allowed to realize an off/on fluorescent probe. As these examples demonstrate, functional chemical

combinations contribute to bioanalysis.

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Koji Suzuki Professor Department of Applied Chemistry, Keio University Address: 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan Phone : +81 (0)4 55 66 15 68 FAX: +81 (0)4 55 66 15 68 E-mail: suzuki@applc.keio.ac.jp http://suzuki-lab.applc.keio.ac.jp/

Academic Carrier: - Vice President of the Japan Society for Analytical Chemistry (JSAC) (since 04/2011) - Professor of Faculty of Science and Technology at Keio University (since 04/1998) - Associate Professor of Faculty of Science and Technology at Keio University (04/1993-03/1998) - Visiting Professor at ETH-Zurich (09/1990-01/1992) - Assistant Professor of Faculty of Science and Technology at Keio University (04/1988-03/93) - Research Associate of Faculty of Science and Technology at Keio University (04/1982-03/1988) Awards: - The Japan Society for Analytical Chemistry/ Advanced Analytical Technology Award - The Japan Analytical Instruments Manufacturers Association (JAIMA) Award (09/2009) - The Japan Society for Analytical Chemistry/ JSAC Award (09/2007) - The Hitachi Environment Foundation/ Environment Prize (06/2005) - The Japan Air Cleaning Association/ Technology Award (05/2005) - Keio University/ Gijyuku Award (11/2003) - The Chemical Society of Japan/ CSJ Award for Creative Work (03/1997) - The Japan Society for Analytical Chemistry/ JSAC Award for Young Scientists Research Area: - Analytical Chemistry: Chemical and Biochemical Sensors

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4th Session Biomimetic molecular funnels with hat and boots Olivia Reinaud Laboratoire de Chimie et Biologie Pharmacologiques et Toxicologiques, CNRS UMR 8601,Université Paris Descartes

Modeling the active site of an enzyme is an important tool for a better understanding of its catalytic cycle. Classically however, biomimetic inorganic chemistry is mainly focused on reproducing the first coordination sphere of the metal ion and little information is available concerning the influence, or even the control, that the microenvironment provided by a protein can have on the reactivity of the metal. The aim of our work is to design supramolecular systems that will mimic both the coordination core and the hydrophobic pocket of a metallo-enzyme active site. Our strategy is to synthesize calix[6]arene-based ligands that allow the control of the coordination sphere of the metal ion together with the approach and the binding of an external molecule. Recent developments will be presented, with a particular emphasis on polytopic receptorsand water-soluble systems. Coquière, D.; Le Gac, S.; Darbost, U.; Sénèque, O.; Jabin, I. ; Reinaud O. Org. Biomol. Chem., 2009, 7, 2485 - 2500 (Perspective).

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Olivia Reinaud Professor Laboratoire de Chimie et Biologie Pharmacologiques et Toxicologiques, CNRS UMR 8601,Université Paris Descartes Address: 45, rue des Saint-Pères, 75270 Paris Cedex 06, France Phone : +33 (0)1 42 86 21 83 FAX: +33 (0)1 42 86 83 87 E-mail: Olivia.Reinaud@parisdescartes.fr http://www.biomedicale.univ-paris5.fr/umr8601/-Chimie-Bioinorganique-.html

Olivia Reinaud was born in 1960 in France. She studied Physics and Chemistry first at Orsay University

(Paris XI), then at Pierre et Marie Curie University (Paris VI) and finally at the Ecole Supérieure de

Physique et Chimie Industrielles de la ville de Paris (ESPCI). Her PhD thesis concerned the development

of new synthetic routes to quinonoid compounds of biological interest, using bio-inspired copper catalyzed

oxidation methodologies in the group of Drs. M. Maumy and P. Capdevielle. She then spent a year as a

postdoc fellow in the lab of Dr. D. Mansuy at René Descartes University (Paris V) and studied the

biochemical aspects of oxidative processes related to the metabolism of linoleic acid by leucocytes.

Rejoining her former lab at the ESPCI as a CNRS researcher, she then developed novel biomimetic

copper catalyzed processes. In order to complete her experience, she took a two year sabbatical and

worked at Delaware University (USA) with Pr. K. Theopold on the stepwise activation of dioxygen by

Cobalt trispyrazolyl borate complexes. Upon her return to France, she started a new project associating

organic, inorganic and supramolecular chemistry with some “bio-inspiration”. After four years at the Ecole

Nationale Supérieure de Chimie de Paris (ENSCP), she ended up back in her postdoc lab, at Paris

Descartes University. She switched her CNRS position for a Professor position in 2001. Her current

research interest now lies in the field entitled “Supramolecular Bio-Inorganic Chemistry”, mainly dealing

with biomimetic metal complexes based on calixarene derivatives.

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4th Session Molecule Recognition Based on Abasic-site-binding Fluorescent Ligands Norio Teramae Department of Chemistry, Graduate School of Science, Tohoku University We have recently proposed a new strategy of ligand-based fluorescence assay for single-nucleotide polymorphisms (SNPs) typing, in combination with abasic site (AP site)-containing DNAs.1) Our method is based on construction of the chemically stable AP site in DNA duplexes, which allows small synthetic and/or biotic fluorescent molecules (ligands) to bind to target nucleotides accompanied by fluorescence signaling. Specific molecular interactions between ligands and bases opposite the AP site or phosphate backbone were confirmed by 1H-NMR1c) and 31P-NMR measurements.1b) Thermodynamic analysis based on isothermal titration calorimetry indicated that the hydrophobicity of a ligand was responsible for the increase in the binding affinity at the AP site.1d) Like aptasensors, the nucleobase opposite the AP site in DNA duplexes can work as a receptor for the detection of small biotic molecules.2)

References [1] (a) J. Am. Chem. Soc., 125 , 8982 (2003), (b) Chem. Commun., 1185 (2006), (c) J. Phys. Chem. B, 113, 1522 (2009), (d) Nucl. Acids Res., 37, 1411 (2009). [2] (a) Angew. Chem. Int. Ed., 45, 1563 (2006). (b) J. Am. Chem. Soc., 131 , 2448 (2009).

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Norio Teramae Department of Chemistry, Graduate School of Science, Tohoku University Address: Aoba-ku, Sendai 980-8578, Japan Phone : +81 (0) 2 27 95 65 49 FAX: +81 (0) 2 27 95 65 52 E-mail: teramae@m.tohoku.ac.jp http://www.anal.chem.tohoku.ac.jp/index_english.html

1972 Bachelor degree at the University of Tokyo 1977 Ph. D at the University of Tokyo 1978 Assistant Professor at the University of Tokyo 1984-5 PostDoc at the University of Florida, USA (Prof. James D. Winefordner) 1987 Lecturer at theUniversity of Tokyo 1990 Associate Professor at Nagoya University 1993- Professor at Tohoku University 2005-7 Chairman of the Tohoku Branch of the Spectroscopical Society of Japan 2007-9 Chairman of the Tohoku Branch of the Japan Society for Analytical Chemistry 2007-9 President of the Spectroscopical Society of Japan 2009-10 Chairman of the Tohoku Branch of the Chemical Society of Japan 2010-- Sendai Science Museum, conference member & chairman

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4th Session Boron Dipyrromethene Dyes: A Toolbox for Molecular Photonics and Light Emitting Devices Raymond Ziessel Laboratoire de Chimie Moléculaire, Ecole Européenne de Chimie, Polymères et Matériaux, ULP, CNRS Electronic energy transfer (EET) plays a critical role in many biological processes and is used by nature to

direct energy to a site where chemical reactions need to be initiated. Such EET can occur over large

distances and can involve many individual molecules of identical, similar or disparate chemical identity.

Advances in spectroscopy and data processes have allowed the rates of EET to be measured on

extremely fast timescales such that improved mechanistic insight becomes feasible. At the same time,

highly sophisticated synthetic operations have been devised that facilitate the isolation and purification of

elaborate multi-component molecular arrays. A key feature of these arrays concerns the logical positioning

of individual units in a way that favours directed EET along the molecular axis or along some other

preferred pathways. Of particular interest is the spectacular growth in the application of boron

dipyrromethene dyes as basic reagents in such artificial photon collectors and these compounds have

dominated the market in recent years because of their synthetic versatility and valuable photophysical

properties. In presentation, recent developments in the field are highlighted in terms of synthesis and

subsequent spectroscopic exploration.

References

R. Ziessel, G. Ulrich, A. Harriman, New J. Chem. 2007, 31, 496 (Highlight article).

G. Ulrich, R. Ziessel, A. Harriman, Angew. Chem. Int. Ed. 2008, 47, 1184 (Review article).

R. Ziessel, A. Harriman Chem. Commun 2011, 611-631 (Feature Article).

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Raymond Ziessel Laboratoire de Chimie Organique et Spectroscopies Avancée (LCOSA), Centre national de la Recherche Scientifique (CNRS), Université Louis Pasteur (ULP), Ecole de Chimie, Polymères, Matériaux (ECPM) Address: 25 rue Becquerel, 67087 Strasbourg Cedex, France Phone : +33 (0)3 90 24 26 89 E-mail: ziessel@unistra.fr http://www-lmspc.u-strasbg.fr/lcosa/

Birth date 23 december 1953 in Colmar (France) PhD in 1982, Organic Chemistry from the University Louis Pasteur of Strasbourg under the supervision of Professor J.-M. Lehn and Dr. Jean Pierre Sauvage Postdoc in 1985/1986 University of California, Berkeley, USA, Professor Robert Bergmann CNRS fellow, Director de Recherche DRCE. Silver Medal in Chemistry CNRS in 2000.

Research Themes:

1) Lanthanide chemistry for fluorescence imaging and immunofluoroassays 2) Metallo-polyacetylene for novel ligand and complexes design 3) Engineering of fluorescent gels and liquid crystals for opto-electronic applications 4) Novel organic fluorophores (Bodipys’): synthetic protocols, methodology, colour tuning 5) Bodipys for excitonic energy transfert and antibody labeling. Scientific production: 453 publications in Internatinal Journals, 13,100 citations and h factor of 62.

16 PCT patents, 324 invited conferences, 22 pD direction.

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4th Session Mainchain-Type Organoboron Polymers: Synthesis and Photoluminescence Properties Yoshiki Chujo Department of Polymer Chemistry, Kyoto University

We have reported a wide variety of organoboron polymers including boron atoms in the main chain by

means of hydroboration polymerization. These polymers exhibited various interesting properties due to

the high electron affinity of boron atoms; strong fluorescence emission, n-type electronic conductivity,

third-order nonlinear optical properties, and so on.

The present paper reports the synthesis and properties of the first example of conjugated polymers

containing organoboron quinolate in their main chain. These polymers were prepared by the

Sonogashira-Hagihara coupling. The polymers exhibited intense green-blue photoluminescence.

Moreover, efficient energy transfer from conjugated main chain to quinoline rings has been indicated.

Similar polymers having boron quinolate in the main chain were also prepared and showed unique

photoluminescent properties.

As other examples of photoluminescent organoboron conjugated polymers having tetracoordinated boron

complexes, poly(cyclodiborazane)s, poly(pyrazabole)s, organoboron diketonate polymers, BODIPY

conjugated polymers and carborane-based polymers are also described. In these polymers, very

interesting and peculiar optical properties were observed. Such examples are extremely high

photo-emissions, fine tuning of emission colors, phosphorescence properties, near-UV fluorescence

emission, near-IR photoluminescence, and aggregation-induced emission behaviors. These

performances would be the topics of the present paper and should be very important in the fields of

electrical, optical, and magnetical applications.

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Yoshiki Chujo Department of Polymer Chemistry, Graduate School of Engineering, Kyoto University Address: Katsura, Nishikyo-ku, Kyoto 615-8510, JAPAN Phone : +81 (0) 7 53 83 26 04 FAX: +81 (0) 7 53 83 26 05 E-mail: chujo@chujo.synchem.kyoto-u.ac.jp http://chujo.synchem.kyoto-u.ac.jp/

Yoshiki Chujo completed his PhD at Kyoto University in 1980 and then joined Nagoya University as an

assistant professor in 1981. In 1983, he joined the group of Prof. J. E. McGrath at Virginia Tech in the

U.S.A. as a postdoctoral research fellow. He returned to Kyoto University as a lecturer in 1986 and has

been Professor of Polymer Chemistry there since 1994. His research interests focus on polymer synthesis,

inorganic polymers, and polymeric hybrid materials. He has published more than 500 papers. The impact of

his work is manifested in the discovery of various new polymerization methodologies, which enabled the

preparation of the first examples of various types of hetero-element containing mainchain-type polymers

showing very unique optical and electrical properties.

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4th Session Ring Polymers and Related Chain Architectures: Synthesis and Molecular Imaging Alain Deffieux* and Michel Schappacher CNRS, Université de Bordeaux, Laboratoire de Chimie des Polymères Organiques The synthesis and study of macromolecules of increasing molecular complexity is a very active research

domain in close relation with the development of molecular materials for nanosciences and

nanotechnologies. In recent years highly-branched combs have gained widespread attention due to their

original structure and unique bulk and solution properties, which strongly differ from their linear

counterparts.

We have recently developed synthetic approaches via the combination of controlled polymerization

processes and coupling reactions allowing the preparation of comb polymers with linear, star-like and

cyclic backbone architecture.

An important aspect of these studies concerns the use of adequate methods to precisely characterize the

final polymers. Direct visualization of isolated macromolecules by Atomic Force Microscopy (AFM) has

appeared to be an efficient approach to investigate these comb polymers at the molecular level (Figure

below).

Our presentation will focus on the synthetic strategies applied to the preparation of cyclic comb polymers

and on the characterization of sets of isolated polymers by AFM. Besides characterization of the molecular

parameters of macrocycles, statistical analysis of large series of macromolecules allowed us to vizualise

for the first time complex ring structures, among which tadpoles, knotted rings, height-shape rings and

catenated rings. Their mechanism of formation during the cyclization process will be discussed.

100 nm100 nm

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Alain Deffieux Research Professor at CNRS, University-Bordeaux Address: LCPO-ENSCBP, 16 avenue Pey Berland 33607 Pessac Cedex France Phone : +33 (0) 5 40 00 84 85 E-mail: deffieux@enscpb.fr http://www.lcpo.fr

▪ Education: 1979: PhD at Paris VI University (Professor Pierre Sigwalt supervisor), ▪ Work Experience: 1988 - present: Research Director (Professor) at LCPO CNRS, Bordeaux-1 University 1981 - 1988 : Research Associate at CNRS, Paris VI and Bordeaux-1 Universities 1979 - 1981 : Post-doctoral fellow, University of North Carolina ( Pr Vivian Stannett) ▪ Research Interests: Catalyst/Initiator Design, Bio-Catalysis Reactivity Control in Polymerizations of vinyl and Heterocyclic Monomers Bio-Inspired Polymerizations Precise Synthesis and imaging of Complex Macromolecules: Cyclics, Stars, Combs, Dr Alain Deffieux, University of Bordeaux, France, get his Ph D in Polymer Science in the group of Pierre Sigwalt at the University Pierre and Marie Curie, Paris. After 2 years spent as associate researcher in the Laboratory of Professor Vivian Stannett at North Carolina University, he joined the Centre National de la Recherche Scientifique at Paris and then moved as Research Professor to Bordeaux University in 1986 where he participated to the creation and development of the Laboratoire de Chimie des Polymères Organiques (LCPO). He is head of a research group with activities focused on precise control of polymerization reactions going from elementary reaction processes to the design of polymers with complex chain architecture. Alain Deffieux is co-author of 330 papers on polymerization processes including about 220 in international journals, 16 book chapters, and 40 patents. He also contributes to 230 lectures and communications in symposia, 160 in international symposia, and gave 60 invited or plenary lectures. ▪Awards : 2009: Grand prix of the French Polymer Group 2010: French-Brazilian FBpol Prize 2010: International Prize of the Japan Society of Polymer Sciences .

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4th Session Greener Molecular Transformation with Bifunctional Molecular Catalysts Takao Ikariya Graduate School of Science and Engineering, Tokyo Institute of Technology Conceptually new chiral bifunctional transition metal-based catalysts originated from Metal-cooperating

ligand effect promoted asymmetric reactions, concerto molecular catalysis, are described. This concerto

molecular catalysis offered a great opportunity to open up fundamental aspects for stereoselective

reductive and oxidative transformation and is now realized to be a powerful and practical and greener tool

to access chiral compounds in organic synthetic chemistry.1 Noticeably, the structural and electronic tuning

of the bifunctional catalyst, for example, a change in the chelating amine ligands causes a drastic change

in the catalytic performance. I will discuss on recent advances on the asymmetric hydrogenation2,

oxidative transformation3, and C–C bond formations4 with the bifunctional catalysts.

References: 1) Org. Biomol. Chem. 2006, 4, 393; Acc. Chem. Res. 2007, 40, 1300; Bull. Chem. Soc. Jpn. 2011, 84, 1. 2) J. Am. Chem. Soc. 2007, 129, 290; Angew. Chem., Int. Ed. 2009, 48, 1324; J. Am. Chem. Soc. 2010, 132, 11414; J. Am. Chem. Soc. 2011, 133, 4240. 3) Angew. Chem., Int. Ed. 2008, 47, 2447. 4) J. Am. Chem. Soc. 2008, 130, 2158; J. Am. Chem. Soc. 2010, 132, 16637; Angew. Chem., Int. Ed. 2010, 49, 8157.

40

Takao Ikariya Graduate School of Science and Engineering, Tokyo Institute of Technology Address: 2-12-1-E4-1 O-okayama, Meguro-ku, Tokyo 152-8552, Japan Phone : +81 (0) 3 57 34 26 36 FAX: +81 (0) 3 57 34 26 37 E-mail: tikariya@apc.titec h.ac.jp http://www.apc.titech.ac.jp/%7Etikariya/index.html

Takao Ikariya completed his Ph.D. degree in 1976 at the Tokyo Institute of Technology and then he was

appointed as an assistant professor in the Department of Synthetic Chemistry at the University of Tokyo.

He discovered a prototype of chiral Ru–BINAP complex and successfully developed asymmetric

hydrogenation with the Ru–BINAP complexes. He spent Prof. Robert H. Grubbs' group at Caltech for one

and a half years in 1979–1981 as a postdoctoral fellow. In 1985, he moved to the central research center

of NKK cop. In 1991, he joined in the ERATO Molecular Catalysis Project of JST, which was directed by

Prof. Ryoji Noyori. Then Ikariya was promoted to full professor at the Tokyo Institute of Technology in

1997. He received the Chemical Society of Japan Award in 2009 and the Humboldt Research Awards in

2011. His current research interests include powerful and practical molecular catalysis in both liquid

solvents and supercritical fluids.

41

5th Session

Green Catalysis inside Dendritic Nanoreactors Didier Astruc ISM, UMR CNRS N°5255, Université Bordeaux1

The modern ecological and economical contrainsts are pushing the chemical community to think of the

replacement of organic solvents by water for organic synthesis. With these ideas in mind, we and others

have designed nanoreactors that should allow to reach this goal, even with water insoluble substrates and

catalysts, under mild conditions. Dendrimers and nanoparticles provide magic media (Scheme below)

that can be designed for that purpose.1 The lecture will compare metallodendritic catalysis whereby the

catalyst is located inside the dendrimer or not, and will point out and illustrate the advantages of

intradendritic catalysis. Examples will be choosen in redox catalysis, catalysis by transition-metal

nanoparticles and using commercial molecular catalysts. process will be discussed.

1. C. Ornelas, D. Méry, E. Cloutet, J. Ruiz, D. Astruc J. Am. Chem. Soc. 2008, 130, 1495-1506. C. Ornelas, J. Ruiz, C. Belin, D. Astruc J. Am. Chem. Soc. 2009, 131, 590-601. E. Boisselier, A. K. Diallo, L. Salmon, C. Ornelas, J. Ruiz, Didier Astruc J. Am. Chem. Soc. 2010, 132, 2729–2742. A. K. Diallo, C. Absalon, J. Ruiz, D. Astruc J. Am. Chem. Soc. 2011, 133, 629-641.

substrate

SiSi

SiNNN

ONN

N

O

NN

NOO

OOO

OO

OO

OO

OO

OO

O

OO

O

O

O

O

O

O

O

O O

O

O

O

O

O

O

O

OO

O

Si

Si

SiNN N O

NN N

ON N

N

O

OO

O OO

O O O

O O O O

OO

O O OO O OO O

O O

OO O

OO

OO

O

OO

O

O

Si

Si

SiN N

NO

NNNO

NNN

O

OO

O

O

O

O

O

O

OO

O

O

OO

OO

O

OO

O

OO

OO

OO

OOO

OOO

OOOO

Ru cata.

product

substrate

SiSi

SiNNN

ONN

N

O

NN

NOO

OOO

OO

OO

OO

OO

OO

O

OO

O

O

O

O

O

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O

O O

O

O

O

O

O

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O

OO

O

Si

Si

SiNN N O

NN N

ON N

N

O

OO

O OO

O O O

O O O O

OO

O O OO O OO O

O O

OO O

OO

OO

O

OO

O

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Si

Si

SiN N

NO

NNNO

NNN

O

OO

O

O

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O

OO

O

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OO

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OOO

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product

42

Didier Astruc ISM, UMR CNRS N°5255, Université Bordeaux 1 Address: 44305 Talence Cedex, France Phone : +33 (0) 5 40 00 62 71 FAX : +33 (0)5 40 00 69 94 E-mail: d.astruc@ism.u-bordeaux1.fr http://astruc.didier.free.fr/welcome.htm

Didier Astruc (born in Versailles) carried out his studies in chemistry in Rennes. After a PhD with Prof. R.

Dabard in organometallic chemistry, he did post-doctoral studies with Prof. R. R. Schrock (2005 Nobel

Laureate) at MIT, Cambridge, Mass., U.S. and later a sabbatical year with Prof. K. P. C. Vollhardt at the

University of California at Berkeley. He became a CNRS Director of research in Rennes, then in 1983 full

Professor of Chemistry at the University Bordeaux 1. He is known for his work on “Electron-Reservoir”

complexes and dendritic molecular batteries, catalytic processes (olefin metathesis, C-C coupling,

catalysis in water) using nanoreactors and molecular recognition using gold nanoparticles and

metallodendrimers. He is the author of three books, 370 scientific publications and the editor of five books

or special issues. He has served as a member of the National CNRS committee from 2000 to 2008 and

the President of the Coordination Chemistry Division of the Société Française de Chimie from 2000 to

2004. Didier Astruc is on the Thompson-Reuters list of the top 100 chemists who have achieved the

highest citation impact scores for their chemistry papers published between 2000 and 2010.

43

5h Session Dynamics and Functional Properties of Precisely Designed Polymer Brushes Atsushi Takahara Institute for Materials Chemistry and Engineering, Kyushu University

Nature utilizes hydrophilic surfaces to achieve unique functionality. In this study, high-density hydrophilic

polymer brushes were prepared on Si-wafer and various substrates by surface-initiated controlled radical

polymerization of vinyl monomers with various functional groups. Super hydrophilicity, antifouling behavior,

low friction behavior, and intelligent adhesion were realized by polyelectrolyte brushes. For example,

poly(3-sulfopropyl methacrylate potassium salt) (PSPMK) and poly{2-(methacryloyloxy)ethyl

phosphorylcholine} (PMPC) brushes with 100 nm thickness showed extremely low friction coefficient under

aqueous media and also repelled both of air bubble and hexadecane droplet in water. Antifouling behavior

in an aqueous environment was observed on the surface of polyelectrolyte brushes. Once the polymer

brush substrate covered with oil layer was dipped into water, the oil detached quickly from the brush surface

due to excellent affinity of polyelectrolyte brushes to water. On the other hand, antifouling behavior was not

achieved by hydrophobic poly(2-perfluorooctylehtyl acrylate) (PFA-C8) brush even though the PFA-C8

brush shows relatively oleophobic property under air atmosphere. Furthermore, the unique reversible

adhesion system was designed from oppositely charged and sulfobetaine type polymer brushes

immobilized on Si-wafer.

44

Atsushi Takahara Professor, Institute for Materials Chemistry and Engineering, Kyushu University Project Leader, JST ERATO Takahara Soft Interfaces Project Address: 744 Motooka, Nishi-ku, Fukuoka 812-0395, Japan Phone : +81 (0) 9 28 02 25 17 FAX: +81 (0) 9 28 02 25 18 E-mail: takahara@cstf.kyushu-u.ac.jp http://talahara.ifoc.kyushu-u.ac.jp/ http://www.soft-interfaces.jp

Education, Academic Backgrond

1983 Dr. Eng., Applied Chemistry, Kyushu University

1983 Research associate, Faculty of Engineering, Kyushu University

1985 Associate Professor, Faculty of Engineering, Kyushu University

1999 Professor, Institute for Materials Chemistry and Engineering. Kyushu University

2004-2007 Program Officer, Research Center for Science Systems, JSPS

2005-2008 Member, Science Council of Japan

2009- Project Leader, JST ERATO

Academic Societies

2008- Vice President, The Society of Polymer Science, Japan

2009- Council member of Pacific Polymer Federation

Awards

• 1995 Rheology Award, Japanese Society of Rheology, “Fatigue Analyses of Solid Polymers based on

Nonlinear Dynamic Viscoelastic Measurements”

• 1999 Fiber Society Scientific Award, The Society of Fiber Science and Technology, Japan, “Analyses

and Prediction of Fatigue Behaviors of Solid Polymers and Fibers in terms of Nonlinear Dynamic

Viscoelastic Measurements” • 2003 Polymer Science Award, The Society of Polymer Science, Japan, “Study on Nanoscale Surface

Structure and Properties of Organic and Polymer Thin Films”

45

5th Session Organophosphorus and Organometallic Chemistry for the Design of pi-Conjugated Systems Régis Réau Université de Rennes1, CNRS, UMR 6226, Sciences Chimiques de Rennes π -Conjugated oligomers and polymers based on aromatic heterocyclopentadienes have attracted strong

interest in recent years owing to their potential applications for electronic devices (light emitting diodes, thin

film transistors, photovoltaïc cells...). The tailoring of these semi-conducting organic materials for improving

their electrochemical and optical properties towards plastic electronic applications necessitates extensive

experimental molecular engineering. We have showed that the phosphole unit is an appealing building block

for this molecular engineering due to its low aromatic character and the versatile reactivity of its P-centre that

allow a structural diversity to be easily generated. The synthesis of π-conjugated systems based on

phosphole synthons and their use as materials for OLEDs, including white-emitting devices, will be

presented. Their coordination chemistry was also exploited towards the design of new helicenes derivatives

with tuneable, large chiroptical properties.

For recent references see: Adv. Mat., 2009, 21, 1261 ; J. Am. Chem. Soc., 2009, 131, 3183 ; Chem. Eur. J., 2010, 16, 11340, 2010, 16, 5976 and 2010, 16, 7143; Angew. Chem. Int. Ed., 2010, 49, 99; J. Am. Chem. Soc., 2011, 133, 3800 ; Chem. Eur. J., 2011, 4, 1357 ;

46

Régis Réau Université de Rennes1, CNRS, UMR 6226, Sciences Chimiques de Rennes Address: Campus de Beaulieu, 35042 Rennes cedex, France Phone : +33 (0)2 23 23 57 84 E-mail: regis.reau@univ-rennes1.fr http://www.scienceschimiques.univ-rennes1.fr/equipes/om2/phosphore-materials-molecular

Régis Réau obtained his PhD degrees at the University of Toulouse in 1988 under the supervision of

Professor I. Tkatchenko investigating novel phosphorus ligands in homogeneous catalysis. He received

an Alexander von Humboldt Postdoctoral Fellowship to work with Professor W. Keim in Aachen (1989) on

asymmetric catalysis. Subsequently, he joined the group of G. Bertrand in Toulouse becoming a

permanent member of the CNRS. He has been working on the synthesis of anti-aromatic species, novel

super-Lewis acids and heterocyclic P-derivatives. In 1997, he was appointed professor at the University of

Rennes. His current research interests involve the synthesis of organophosphorus and organometallic

pi-conjugated materials for optoelectronic applications (OLEDs, NLO, …). In 2001, he was appointed

junior member of the Institut Universitaire de France. He has published about 128 papers and five

chapters in books.

47

5th Session Carbon-Carbon Bond Forming Strategy through C–H and C–C Activation Tamejiro Hiyama Research and Development Initiative, Chuo University The cross-coupling reaction allows us to make C–C Bonds for extension of p-conjugate systems exactly at

the designed position with the designed stereochemistry, producing, however, metallic residues as wastes.

In view of the green chemistry in the future, the transformation of 100% atom economy hopefully without

prefunctionalization is ideal. To this end, we have studied C–CN bond activation using a Ni(0)/Lewis acid

co-catalytic system to make unsaturated bonds insert between the bond. An example is the reaction of

benzonitrile with 4-octyne using Ni(cod)2 (1 mol%), PCyPh2 (2 mol%) and AlMe3 (4 mol%) in toluene at

50 °C to give (Z)-2,3-dipropylcinnamonitrile in 97% yield in 16 h. Even acetonitrile undergoes the similar

transformation. The same catalyst system was found to activate C–H bonds in heteroaromatic and

polyfluoroaromatic cores and allow alkynes and alkenes insert between the bonds. Recent example

demonstrates that exclusive C-4 alkylation of pyridine is achieved using 1-alkene as the alkylating agent,

Ni(cod)2 (5 mol%), MeAl(OC6H2-2,6-tBu2-4-Me)2 (20 mol%) as a bulky Lewis acid and IPr (5 mol%) as a

bulky carbene ligand for Ni to give 4-alkylpyridines in high yields as a single regioisomer with normal/iso

ratios of >95:5.

48

Tamejiro Hiyama Research & Development Initiative, Chuo University Address: 1-13-27 Kasuga, Bunkyo-ku, Tokyo 112-8551, Japan Phone : +81 (0) 3 38 17 16 28 FAX: +81 (0) 3 38 17 16 06 E-mail: thiyama@kc.chuo-u.ac.jp http://www.chem.chuo-u.ac.jp/~omega300/index.html

Born in Osaka, 1946, Tamejiro Hiyama started his academic career in 1972 as Assistant Professor at

Kyoto University, received the Doctor of Engineering degree in 1975 from Kyoto University, and spent a

postdoctoral year at Harvard University. In 1981, he joined Sagami Chemical Research Center as

Research Fellow, Group Leader, to start his own research team. There, he was promoted to Senior

Research Fellow and then to Executive Research Fellow before he moved in 1992 to Research Laboratory

of Resources Utilization, Tokyo Institute of Technology, as Professor of Newer Metal Resources. In 1997,

he was invited back to Kyoto University as Professor of Organic Materials at Department of Material

Chemistry, Graduate School of Engineering, and worked there until retirement in 2010 due to the age limit

of 63. Since then he is RDI Professor of Chuo University. Research Achievements: carbenoid reagents

for selective organic synthesis, Barbier-type carbonyl addition of Cr reagents (Nozaki-Hiyama-Kishi [or

simply NHK] reaction), nitrile addition of magnesium ester enolates (Hiyama reaction), cross-coupling

reaction with organosilicon reagents (Hiyama coupling), oxidative desulfurization-fluorination for synthesis

of organofluorine compounds, carbostannylation, carbocyanation and hydro(hetero)arylation reactions,

novel materials for light-emitting and liquid crystals. Awards: Young Chemist Award of the Chemical

Society of Japan 1980; Japan Liquid Crystal Society Award 2004; Synthetic Organic Chemistry Award

2007; the CSJ Award 2008. Current Activities: Vice Chairman of JSPS 116th Committee; Editor-in-Chief

of Chemistry Letters; President of Japanese Liquid Crystal Society.

49

CVs (Chairpersons)

50

Chairperson – 1st Session

Paolo Samori Institut de Science et d'Ingénierie Supramoléculaires (ISIS) of the Université de Strasbourg (UdS)

Paolo Samorì (Imola, Italy, 1971) is full professor (PR1) and senior member as well as deputy director of

the Institut de Science et d'Ingénierie Supramoléculaires (ISIS) of the Université de Strasbourg (UdS)

where he is also Director of the Nanochemistry Laboratory. He is also a junior member of the Institut

Universitaire de France (IUF) from 2010 til 2015. He obtained a Laurea (master’s degree) in Industrial

Chemistry at University of Bologna in 1995. In 2000 he received his Ph.D in Chemistry from the Humboldt

University Berlin (Prof. J.P. Rabe). He was permanent research scientist at Istituto per la Sintesi Organica

e la Fotoreattività of the Consiglio Nazionale delle Ricerche of Bologna from 2001 til 2008, and Visiting

Professor at ISIS from 2003 til 2008. He has published >145 papers on applications of scanning probe

microscopies beyond imaging, hierarchical self-assembly of hybrid architectures at surfaces,

supramolecular electronics, and the fabrication of molecular-scale nanodevices. His work has been

awarded various prizes, including the young scientist awards at EMRS (1998) and MRS (2000) as well as

the IUPAC Prize for Young Chemists 2001, the Vincenzo Caglioti award 2006 granted by the Accademia

Nazionale dei Lincei ,the “Nicolò Copernico” award 2009 (Italy) for his discoveries in the field of

nanoscience and nanotechnology, the prix "Guy Ourisson" 2010 du Cercle Gutenberg and the ERC

starting grant 2010. He is member of the advisory board of Advanced Materials and ChemPhysChem

(Wiley-VCH), Journal of Materials Chemistry as well as Nanoscale (RSC). Bibliometrics: >3500 citations,

h-index=33.

51

Chairperson – 2nd Session

Pierre Rabu IPCMS - Département de Chimie et des Matériaux Inorganiques (DCMI)

Pierre Rabu (born 1964) obtained his PhD in solid state chemistry from University of Nantes, France, in

1990. He then became CNRS researcher in the Institute of Physics and Chemistry of Strasbourg, France,

to work on low-dimensional magnetic materials. He was a JSPS research fellow at Institute for

Fundamental Organic Chemistry, Kyushu University, Fukuoka, Japan, in 1996 and visiting fellow of

Advanced Materials Research Institute, University of New Orleans, USA, in 2001. He received the 1998

prize of the Solid State Chemistry division of the French Chemical Society. Since 2005, Pierre Rabu is

director of research and focuses his activities on the design of hybrid organic-inorganic materials exhibiting

multifunctionality. In 2005-2008, he was director of the CNRS national group of research on Multifunctional

Hybrid Materials.

52

Chairperson – 3rd Session

Pierre Braunstein CNRS Research Director, Laboratoire de Chimie de Coordination, Institut de Chimie (UMR 7177 CNRS), Université Louis Pasteur Address: 4, rue Blaise Pascal, F-67081 Strasbourg, France Phone: +33 (0) 3 68 85 13 08 Fax: +33 (0) 3 68 85 13 22 E-mail: braunstein@unistra.fr

Pierre Braunstein graduated from the Ecole Nationale Supérieure de Chimie de Mulhouse and obtained

his Dr. Ing. and Doctorat d'Etat from the Université Louis Pasteur (ULP) in Strasbourg. He is Director of

Research with the CNRS and the Director of the Coordination Chemistry Laboratory (Institut de Chimie,

UMR 7177 CNRS) of the Université de Strasbourg. His main research interests concern the inorganic and

organometallic chemistry of the transition and main group elements where he has (co)authored ca. 450

scientific publications and review articles. He is a member i.a. of the French Académie des Sciences and

the German National Academy Leopoldina, and is a Fellow of the Royal Society of Chemistry.

Recent reviews

* F. Speiser, P. Braunstein, L. Saussine, Catalytic Ethylene Dimerization and Oligomerization.

Acc. Chem. Res. 2005, 38, 784-793.

* P. Braunstein, Bonding and organic and inorganic reactivity of metal-coordinated phosphino enolates.

Chem. Rev. 2006, 106, 134-159. * S. Sculfort, P. Braunstein, Intramolecular d10-d10 interactions in heterometallic clusters of the transition metals. Chem. Soc. Rev. 2011, 40, 2741-2760.

53

Chairperson – 4th Session

Jean Weiss Chimie des Ligands à Architecture Contrôlée (CLAC) Institut de Chimie de Strasbourg - UMR7177, CNRS-Université de Strasbourg

Dr. Jean WEISS is a CNRS Research Director at the “Institut de Chimie de Strasbourg”. He received his

PhD. degree under the supervision of Dr. Jean-Pierre Sauvage in 1986 and pursued post-doctoral studies

at UCLA with Prof. Donald J. Cram and at the MPI in Heidelberg with Prof. Dr. Heinz A. Staab as an A. von

Humboldt fellow. He started as a CNRS Research Associate in 1988 and was appointed Research

Director in 1998. Since 2004 he is the leader of the CLAC (Controlled Ligand Architecture in Coordination

chemistry) team, which has recently merged with the former Laboratoire de Chimie des Porphyrines,

directed by Dr. Henry Callot. The main scientific interests of the team focus on the coordination chemistry

of metallic complexes and control of their physical/chemical properties using rigid and semi-rigid ligands,

the synthesis and studies of tetrapyrrolic compounds as molecular materials, electron and energy transfers

in supramolecular assemblies, heme proteins models and self-organization in solution and on surfaces.

54

Chairperson – 5th Session

Dominique Matt Laboratoire de chimie inorganique et catalyse Institut de Chimie de Strasbourg UMR 7177 CNRS-UDS Address: 1, rue Blaise Pascal, 67008 Strasbourg cedex, France E-mail: dmatt@unistra.fr http://inorganics.online.fr/

Dominique Matt is a CNRS research director within the Strasbourg Chemistry Institute. He studied

chemistry at the Ecole Nationale Supérieure de Chimie de Strasbourg and obtained his Doctorat d'Etat in

1980 at the Université Louis Pasteur with Pierre Braunstein. After a postdoctoral position with Professor L.

M. Venanzi at the ETH, Zurich, he spent one year at BASF-Ludwigshafen (Germany), where he developed

a low-pressure process for the synthesis of acetic acid. Since 1983, he has held a position in the CNRS at

the Université of Strasbourg, where he became Directeur de Recherche in 1991. His research interests are

centered at the interface of coordination, organometallic and supramolecular chemistry, with an emphasis

on the study of metallo-cavitands. He is author of over 200 publications and holder of 7 patents.

Selected publications

1. "Os-chelating behaviour of a cavity-shaped diphosphane", R. Gramage-Doria, D. Armspach, D. Matt,

and L. Toupet, Angew. Chem. 50, 2011, 1554-1559

2. "Cavity-shaped Ligands. Calix[4]arene-based monophosphanes for fast Suzuki-Miyaura cross-coupling", L.

Monnereau, D. Sémeril, D. Matt, L. Toupet, Chemistry, Eur. J. 16, 2010, 9237-9247

3. "Calix[4]arene-phosphine dimers: precursors of flexible metallo-capsules and self-compacting molecules", S.

Sameni, M. Lejeune, C. Jeunesse, D. Matt, L. Toupet, Chemistry, Eur. J. 15, 2009, 10446- 1045

4. "Self-mediated, stereoselective oxidation of thia-capped cyclodextrins", D. Armspach, D. Matt, L. Toupet, Angew.

Chem. Int. Ed. 48, 2009, 4555-4558 5. "Resorcin[4]arene-derived mono- and diphosphines in Suzuki cross-coupling", H. El Moll, D. Sémeril, D. Matt, L.

Toupet, Adv. Synth. Catal. 352, 2009, 901-908

55

CVs (Scientific Coordinators)

56

Organizer

Jean-Pierre Sauvage Université de Strasbourg

Research Fields : chemical topology, catenanes and rotaxanes, molecular knots, molecular machines, artificial photosynthesis Professional Career : 2009~present Professor Emeritus (University of Strasbourg) and Distinguished Visiting Scholar (Northwestern University) 1979~2009 CNRS Director of Research 1981~1984 University Professor 1971~1979 CNRS Research Fellow A few selected awards : 1988 CNRS Silver Medal 1991 Izatt-Christensen Award in Macrocyclic Chemistry 1994 Prelog Gold Medal, ETH-Zürich (Switzerland) 1997 Member of the French Academy of Sciences 2000 Centenary Lecturer and Medal (Royal Society of Chemistry, United Kingdom) 2005 Pierre Süe Prize of the French Society of Chemistry 2005 Catalan Sabatier Prize of the Royal Spanish Society of Chemistry (RSEQ) 2008 RB Woodward Award in Porphyrin Chemistry 2009 Japan Coordination Chemistry Society Award 2010 Honorary Doctorate, University of Zurich More than 20 Named Lectureships in Europe, Japan, Australia, Israël or in the USA Publications and Citations : About 470 publications and 520 lectures. Sauvage is a "HighlyCited" chemist (more than 25,000 citations with an average citation number of 59 per publication); h-index = 84.

57

Organizer

Kazuhiko Saigo Kochi University of Technology Address: Miyanokuch, Tosayamada, Kami, Kochi 782-8502, Japan

Education: Undergraduate Studies: Tokyo Institute of Technology, Bachelor of Science, 1969 Doctor of Science, Tokyo Institute of Technology, 1976 (Supervisor: Prof. Teruaki MUKAIYAMA) Appointments: Research Associate, Dainippon Ink and Chemicals Industries, 1969-1972 Research Associate, Tokyo Institute of Technology, 1972-1973 Research Associate, The University of Tokyo, 1973-1976 Lecturer then Associate Professor at Saitama University, Saitama University, 1976-1982 Post-Doctoral Research Fellow at Université Louis Pasteur, France, 1979-80 (Prof. J.-M. LEHN) Associate Professor, The University of Tokyo, 1982-1993 Professor, The University of Tokyo, 1993-2010 Professor, Kochi University of Technology, 2010-2011 Vice President, Kochi University of Technology, 2011-

58

Note

Note

59

Centre National de la Recherche Scientifique 3, Rue Michel-Ange 75794 Paris, France

Tel : +33 (0)1 44 96 40 00 Fax : +33 (0)1 44 96 48 56

http://www.cnrs.fr/

Faculté de Chimie, Université de Strasbourg 4, Rue Blaise Pascal

67081 Strasbourg, France Tel : +33 (0)3 68 85 16 66 Fax : +33 (0)3 68 85 17 49 http://www.unistra.fr/

JSPS Strasbourg Office Maison universitaire France-Japon

42a, Avenue de la Forêt-Noire 67000 Strasbourg, France Tel : +33 (0)3 68 85 20 17 Fax : +33 (0)3 68 85 20 14 jsps@japon.u-strasbg.fr

http://jsps.u-strasbg.fr/