Oral Care Products

8/6/2019 Oral Care Products

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ORAL CARE

PRODUCTS

Tooth paste, tooth powders, Mouth

washes



Introduction

Tooth problems

Acquired pellicle

Plaque

Calculus( tartar)

Food debris

Dental caries

Periodontal diseases

Dentifrice



Dentifrice

Requirements of a dentifrice

Should effectively clean teeth of food debris, plaque and stains

Should leave a sensation of cleanliness &freshness in the mouth

Non-toxic, pleasant, & convenient to use

Stable during commercial shelf life

Economical

Conform to national standards for its abrasivity to enamel

Any claims made should be substantiated by appropriate data



Formulation

Abrasive

Detergents & foaming agents

Humectants

Binding agents

Sweetening & flavoring agents

miscellaneous



Formulation

Abrasives

Precipitated chalk Aragonite (orthorombic crystals)

Calcite (rhombohedral) Calcium phosphate

Dicalcium phosphate dihydrate (DCP)

Anhydrous dicalcium phosphate

Tricalcium phosphate

Calcium pyrophosphate

Other phosphates Sodium metaphosphate( used in fluoride containing

toothpaste)

Ammonium phosphate

Hydrated alumina



Formulation

Detergents & other foaming agents

Sodium lauryl sulphate

Special attention should be given regarding the taste

Sodium Lauryl Sarcosinate

Anti enzymatic activity

Sodium lauryl sulphoacetate

Acrid taste Slightly alkaline pH

Other detergents

Sodium coconut monoglyceride



Formulation

Humetants

Prevent drying out of the product

Imparts plasticity

Glycerine, glossy product

polypropylene glycol,softer consistancy

Sorbitol solution (70%), high viscosity, firm

toothpaste, good plasticity.



Formulation

Binding agents

Hydrophilic colloids

Disperse, swell or absorb water , form a

viscous liquid phase Natural gums (gum tragacanth, gum arabic)

Cellulose derivatives (CMC, Sodium CMC,

HEC)

Starch ethers , Cellulose ethers , MC, HEC, carrageen, non

ionic

Synthetic resins, polyox, carbopol.



Formulation

Sweetening & flavoring agents

Sweetening agents

Saccharin sodium(0.05-0.3%) Chloroform

flavoring agents

Spearmint

Pippermint(high quality from Mentha piperita) Wintergreen

Cinnamon- mint



Formulation

Flavors blended with other essential oils

Clove, cinnamon, anise, caraway,

coriander, eucalyptus, nutmeg, thyme Other oils

Citrus oil

Eugenol

Menthol etc.



Formulation

Miscellaneous agents

Preservatives Methyl parahydroxy benzoate(0.15%)

Propyl parahydroxy benzoate(0.02%) Anti microbial

Formaldehyde, dichlorophene

Astringents Zinc chloride

Oxidizing agents Potassium chlorate, sodium perborate

Chlorophyll, deodorizing effect



Formulation

Enzyme inhibitors

Penicillin

Sodium N-lauroyl sarcosinate

Sodium dehydroacetate

Strontium chloride

Treatment of hypersensitivity



Manufacture

SS vessel

Mixers( kneading mixers, dough mixer)

Gels are prepared of the binding agents

In the gels , the powders are added

slowly with constant stirring

Flavouring agents are added Surface active agent is added in the last



Packaging

Tin tubes

Tin coated lead tubes

Aluminum tubes

Corrosion of tubes minimized by coating

with wax or lacquering

Stannous fluoride containing toothpastes

not packed in Aluminium tubes Collapsible tubes of polyolefins

Bioburden



Evaluation of abrasiveness of dentifrice &

dentifrice ingredients Fixed teeth in plaster of Paris, brush them with

different dentifrice by hand using toothbrush.

Changes in the diameter of a grounded tooth----

-- to determine abrasion characteristics of dentifrice.

Micrometer gauge sensitivity 0.001 inch

Antimony block( 100g) on revolving plate

Loss in weight of antimony block Reference: PP Sharma Page no.805-808



Tooth Powders

Camphorated chalk

Cracking of tooth enamel

Abrasive

Detergent

Flavoring & sweetening agents



Formulation

Dental soap powder

Selected fatty acids

Sodium palmitate soap

SLS detergent

Flavored with essential oils

Sodium saccharin sweetening agents

Sodium benzoate

Smoker¶s teeth, tobacco stains



Tooth Powders

Indian standard for tooth powders

Type ± 1 foaming

Type- 2 non-foaming

Fineness test

Foaming power

Refer PP Sharma pg no. 790



Manufacturing of toothpowder

Small quantity ingredients are mixed first

Mixture is added to remaining ingredients.

Non- free flowing powders Granulation

Packed in metallic cans with dispensor

Plastic containers

Facilities for mfg of blck tooth powder & white powder should be separate



Mouth washes

Liquid dentifrices

Ready to use

Concentrated form

Three types

Mouthwashes containing anti-bacterial

Mouthwashes containing fluoride

Mouthwashes containing minerals

(astringents)



Functions of mouthwashes

Rinsing food debris from mouth

Reduction in total bacterial count in

mouth

Imparting flavor to the mouth cavity

Imparting flavor to the breath



Deodorizing effect

Mechanical removal of fermentative

debris between teeth & other tissues

Inhibition of bacterial & enzymatic activity in mouth

Chemical reaction

Masking of unpleasant odour with pleasant odour



Manufacture of mouthwashes

Glass lined mixing vessels

SS 316

Mixing vessels preferably should have

chilling coils

Filtration before filling

Filter aids Fuller¶s earth

Pure talc

Documents

Oral Care Products