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HELMBERG-SCORE updated due to the HLA nomenclature changes 4.001T / 2010 A brief description.

Olerup SCORE bennefits

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Due to the HLA nomenclature changes, the Helmberg SCORE™ is now updated with focus on userfriendliness and simplicity. In the new version, 4.001T, an application of new HLA Nomenclature enables instant switching between the old and the new nomenclature any time for each typing. Typing specific preferences for old/new nomenclature are stored, and a master switch is available for each front end to use the old or new nomenclature. This way, you still have the freedom to choose as you like depending on your own needs.

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Page 1: Olerup SCORE bennefits

HELMBERG-SCORE™ updated due to the HLA nomenclature changes

4.001T / 2010

A brief description.

Page 2: Olerup SCORE bennefits

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Due to the HLA nomenclature changes, the Helmberg SCORE™ is now updated with focus on userfriendliness and simplicity. In the new version, 4.001T, an application of new HLA Nomenclature enables instant switching between the old and the new nomenclature any time for each typing. Typing specific preferences for old/new nomenclature are stored, and a master switch is available for each front end to use the old or new nomenclature. This way, you still have the freedom to choose as you like depending on your own needs. Once you have downloaded the new version, you will find that the new features of the Helmberg SCORE™ have been developed so that the conversion from the old to the new nomenclature will be made as easily as possible for the laboratory staff. The following new benefits are to be found:

Conversion/teaching tool for information of old/new allele nomenclature.

Linking back and forth between old and new.

Complete list for each locus both for old and new alleles.

Filter functions to select a group of old or new alleles and display the equivalents.

Combined view of frequency status, old /new name, serological equivalent, G-name, P-name.

The software design is integrated with Olerup SSP®, and is to be used with the Olerup SSP® products. Basically, you will find that the new interface remains almost the same as you and your staff, are used to seeing in your daily work. There is no need for extra education or changes in routines. The new features are simple, and will be learned as the user tries out the options. Please take a moment to look through the following basics.

Here are your new benefits:

HELMBERG-SCORE™ 4.001T

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This is the new Helmberg SCORE™ start screen. The buttons activating the different functions are displayed on the left hand side. To create a patient record, click on “Patient/sample”.

The new 4.001T version

Previous version

Starting:

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This option is the most essential feature of the new 4.001T version. Since the nomenclature transition will create different needs during the change over, we give you the option to choose in every single situation. The typing specific preferences for old/new nomenclature are stored in the software. You can go from old to new, as well as new to old. Or to User Defined Nomenclature and reverse. The instant switch is in the upper left corner.

Click for Old Nomenclature

Click for User Defined Nomenclature

Click for New Nomenclature

The Nomenclature switch:

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Start Helmberg SCORE™. The new patient file-card template appears for entry of individual Patient as well as Sample data.

The new 4.001T version

Previous version

Creating a patient record:

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To create a new patient, click on “Patient/sample” and confirm by clicking on “Main”. Enter the following: Family name /first name and sample ID or Patient ID and sample ID.

The new 4.001T version

Previous version

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To create a gel click on “Gel” in the menu bar and “New” on the left side of the Helmberg SCORE™ screen. The gel data window opens.

The new 4.001T version

Previous version

Entering results:

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Click on “New”. Helmberg SCORE™ opens a new window for you to select an Olerup SSP® typing kit (e.g. DR low resolution kit) from the list of imported Olerup SSP® kits.

The new 4.001T version

Previous version

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The new 4.001T version

Previous version

Click “Insert typing kit” to integrate additional Olerup SSP® high resolution kit(s) into the gel and follow the procedure mentioned on page 9.

Gel Screen:

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The new 4.001T version

Previous version

The space on the gel picture is limited to 96 positions. If all positions of the gel are covered – click on “New” to start a new gel.

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Click “Analysis” to calculate the results. The check box “nomenclature 3.x” allows the flexible application of the new Allele Nomenclature, i.e. instant switch between old and new nomenclature. If the check box is checked, the result will be displayed according to the new nomenclature. If the check box is unchecked: the result will be obtained according to the old nomenclature. Click “Analyse” to start the calculation.

The new 4.001T version

Analysis screen:

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The new 4.001T version

Previous version

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If “nomenclature 3x” is checked, the high resolution result will be displayed according to the new nomenclature. If “nomenclature 3x” is unchecked, a high resolution result will be displayed according to the old nomenclature.

High resolution result with OLD nomenclature

High resolution result with NEW nomenclature

Analysis Screen – High resolution result: presentation of data

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Click on “Main” to receive patient file-card with total information displayed for patient/sample.

The new 4.001T version

Main screen with total information

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Click “Print” to print typing results from the patient file-card. There are different print options.

The new 4.001T version

Print functions:

Previous version

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Print out – results displayed according to old nomenclature.

Print out – results displayed according to new nomenclature.

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New features in 4.001T:

Tool contains a complete list for each locus for old alleles and new alleles. A drop down box allows the entering (or scrolling) of the new/old allele name for each locus to obtain the new/old allele name. A complete list of all alleles for each locus is displayed, with frequency status, old name, new name, serology, G-group/name and P-group/name.

Conversion and teaching tool

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The Typing kit import function: reduction to kits that are currently in inventory. The filter function allows kits to be listed based on allele groups. The sorting function allows sorting according to typing kit name, batch or expiry date. Automatic cleaning of database of unused typing kits before import

Typing kit import

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Click on “Typing Kits” to activate “Typing construction set”.Tool to be used to check all existing primers and mixes for specificity and localization.

Typing kits – information screen

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You laboratory will be defined by ”Lab Code”. When registering, please fill in all field and accept the Terms & Conditions. Once you have completed the firm and sent the registration, you will recieve an e-mail with User Name and Password to the e-mail addres stated in your registration. Other users from the same laboratory will be able to register in a shorter way, using the built in data from the first registration.

Registration:

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Once you have completed the registration, and for the coming updates, you will need to sign in using the User Name and Password given at the first visit.

Login:

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Distributed by:

www.olerup.com

Olerup-SSP®® AB is ISO 9001:2008 and ISO 13485:2003 certified. Olerup-SSP®® AB is IVD certified in accordance with the requirements of the IVD Directive 98/79/EC. Olerup-SSP®® HLA Typing Kits are FDA cleared and licensed by Health Canada.

Olerup-SSP® ABAddress: Hasselstigen 1SE-133 33 Saltsjöbaden, SwedenE-mail: [email protected]: +46 8 717 88 27. Fax: +46 8 717 88 18

OLERUP GmbHAddress: Loewengasse 47/6, 1030 Vienna, Austria Orders and support: [email protected] Tel: +43-1-710 15 00. Fax: +43-1-710 15 00 10

OLERUP IncAddress: 901 S. Bolmar St., Suite R West Chester, PA 19382Orders and support: [email protected] Tel: 1-877-OLERUP1. Fax: 610-344-7989

Manufactured by:

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www.Olerup SSP®.com

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HELMBERG-SCORE™

4.001T / 2010

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