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Odds and Ends
• Drawing an EKG waveform properly• What to include in your hemorrhage
diagram (Tips and Help Schedule at http://webs.wofford.edu/davisgr/bio342/hemorrhagediagramtips.htm
– Hypovolemic shock?– Death?– Whatever you can do well in 15 minutes!
• Revised Abstracts may be turned in anytime but no later than the last Friday of class (Dec 7th.)
1QQ # 28 for 10:30Answer one
1. Diagram the response to a drop in oxygen delivery to the kidney.
2. Diagram the effects of sympathetic stimulation of systemic arterioles that leads to an increase in mean arterial pressure.
3. Diagram the effects of sympathetic stimulation of veins that leads to an increase in mean arterial pressure.
ACE expressed on luminal surface of pulmonary endothelial cells.
Gradient for CO2 is only 6 mmHg;CO2 is more 20x more soluble and permeable than O2
Ventilation by Bulk Flow
Gas exchange by Diffusion
Gas exchange
Where should the receptors be for the negative feedback loop for homeostasis?
Why the difference in partial pressures in Air and Alveoli?
Peripheral Chemoreceptors1) Carotid bodies (not carotid sinuseswhich are baroreceptors)2) Aortic bodies (not aortic arch baroreceptors)
Central Chemoreceptors in medulla (sensitive to H+ in interstitial fluid of medulla)
To ponder: Why should there be three sets of chemoreceptors?
RespiratoryPhysiologyThe physics of air flow
1) Flow in tubes
2) Ventilation
Poiseulle’s equation
Upper
Respiratory
Tract
The Structure underlying the function:
Lower
Respiratory
Tract
Bronchitis= infection/inflammation of conducting airwaysAsthma = smooth muscles contract →increase resistance to
airflow in conducting airways.
Intercostal muscles
Pneumothorax (unilateral due to each lung having its own compartment.
Greg R. and the story of spontaneous pneumothorax
Visceral pleura and parietal pleura separated by fluid-filled pleural cavity which allows lung and chest wall to slide relative to each other but remain adhered unless air enters the pleural cavity (which leads to collapse of the lung and outward expansion of chest wall on that side.)
Upper Tract Sleep Apneaa)obstructive,
b)central
&
CPAP
Continuous Positive Airway Pressure
Bronchopulmonary segments and Surgical resection
Bronchopulmonary segments and Surgical resection
Why is lung cancer so common?Why is lung cancer so common?
How are the delicate living tissues of the respiratory protected?
How are the delicate living tissues of the respiratory protected?