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clinically as patches, erosion, plaques, papules, and nodules
with hyperkeratotic, verrucous, pigmented red or white changes. The
progression of VIN, usual type, toinvasive cancer in untreated
patients has been unequivocally demonstrated,especially in women
over 30 years of age or immunocompromised women. A variantof VIN,
usual type, associated with genital warts or pregnancy is seen in
some younger women and can regress spontaneously.
VIN, differentiated type, is not associated with HPV and is
related to lichen sclerosaand/or squamous cell hyperplasia. It is a
less common diagnosis usually seen inolder women. It usually
presents as a warty papule or hyperkeratotic plaque. It iscommonly
seen during follow up of women who have been treated for
lichensclerosus or invasive vulvar cancer.
Rarely, a pagetoid type of VIN is seen that cannot be classified
as either VIN, usualtype, or VIN, differentiated type. This type of
VIN can be termed VIN, unclassified.
2006 Lippincott Williams & Wilkins, Inc.
Squamous Vulvar Intraepithelial Neoplasia: 2004 Modied Ter...
http://journals.lww.com/obgynsurvey/Abstract/2006/03000/S...
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