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8/20/2019 Obesity and the Mind: A Chicken and Egg Problem?
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©2016 MFMER | slide-1
Obesity and the Mind:
A Chicken-and-Egg P!ble"
#aen $% &!the' Ph(' A$PP' )P
*ati!nal Pess F!+ndati!nFeb+ay 2,' 2016
8/20/2019 Obesity and the Mind: A Chicken and Egg Problem?
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©2016 MFMER | slide-2
(iscl!s+e
Releant .inancial elati!nshi/s
*!ne
O..-label inestigati!nal +ses
*!ne
8/20/2019 Obesity and the Mind: A Chicken and Egg Problem?
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©2016 MFMER | slide-,
Obecties
(isc+ss /sych!l!gical .act!s that in.l+ence:
Obesity
eat"ent !. !besity
$ehai!al inteenti!n
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©2016 MFMER | slide-34!+ce: he Obesity 4!ciety 5n.!ga/hic ask F!ce' *!e"be 201
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©2016 MFMER | slide-
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Obesity and (e/essi!n
!tal Men 7!"en0
10
1
20
2
,0
,
30
3
0
3,%2
,6%8
36%9
,, ,2%6 ,,%3
Age-adjusted percentage of adults aged 20 and over who were obese, by sex and depression status: United States, 200!20"0
(e/essi!n *! (e/essi!n
#ercent
Patt )A' $!dy (% (e/essi!n and !besity in the ;%4% ad+lt h!+seh!ld /!/+lati!n' 200
8/20/2019 Obesity and the Mind: A Chicken and Egg Problem?
7/36©2016 MFMER | slide-9
Obesity and (e/essi!n
)!ngit+dinal analysis
Obese /es!ns: > isk !. de/essi!n
(e/essed /es!ns: 8> isk !. !besity
*! di..eences bet?een "en and ?!"en
M!e /!n!+nced a"!ng A"eicans
Fl!iana 4% )+//in!' M(@ )e!n!e M% de 7it' M4@ Pa+l F% $!+y' M(' Ph(@ he! 4tinen' Ph(@ Pi" C+i/es' Ph(@ $enda 7% % =% Pennin'
Ph(@ Fans &% Bit"an' M(' Ph(% Oe?eight' Obesity' and (e/essi!n: A 4yste"atic Reie? and Meta-analysis !. )!ngit+dinal 4t+dies% Arch
Gen Psychiatry. 2010@69,D:220-22% d!i:10%1001achgen/sychiaty%2010%2@
8/20/2019 Obesity and the Mind: A Chicken and Egg Problem?
8/36©2016 MFMER | slide-8
a+"a hist!y
Ete"e !besity ass!ciated ?ith hist!y !. a/e'
"!lestati!n' ci"e icti"iGati!n' P4(
*ati!nal sa"/le !. ,'012 ?!"en
Obesity s+gey sa"/les
20-,2> childh!!d se+al ab+se
F! s!"e /atients' ?eight is /!tectie
Felitti' 1,@ $e?et!n et al%' 201 #ing et al' 16@ $+se et al%' 2003
8/20/2019 Obesity and the Mind: A Chicken and Egg Problem?
9/36©2016 MFMER | slide-
E"!ti!nal eating
A..ect eg+lati!n' esca/e' /hysi!l!gical
Haies by indiid+al
E"!ti!nal eates c!ns+"e "!e s?eet'
high-.at .!!ds
Men: "eal-ty/e c!".!t .!!ds
7!"en: s?eet snacks' cab!hydates
Haies by e"!ti!n
Can i"/act entie /!cess !. ingesti!n
Eni!n"ental in.l+ence
#!nttinen et al%' 2010@ 7ansink et al%' 200,' 2013@ Ees et al%' 201,
8/20/2019 Obesity and the Mind: A Chicken and Egg Problem?
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Macht 2008
Eating changes in es/!nse t! stess
#+"che I Meye 16,D P+del 183D P!//e et al% 18D7einstein et al% 19D0>
10>
20>
,0>
30>
0>
60>
90>
80>
eat "!e
eat less
8/20/2019 Obesity and the Mind: A Chicken and Egg Problem?
11/36©2016 MFMER | slide-11
*ight Eating 4ynd!"e
M!ning an!eia
Eening hy/e/hagia
2-0> cal!ic intake a.te eening "eal
A?akening !ncenight , nights?eek
C!ns+"/ti!n !. high cal!ie snacks d+ing
a?akenings M!e c!""!n d+ing stess.+l /ei!ds
;/ t! 30> !. /atients
Allis!n I 4t+nkad' 2003
8/20/2019 Obesity and the Mind: A Chicken and Egg Problem?
12/36©2016 MFMER | slide-12
$inge Eating (is!de
)age a"!+nt' sh!t ti"e' l!ss !. c!nt!l
Ra/id' secetie' +ntil +nc!".!tably .+ll
Pealence: ,-> !. ?!"en' 2> !. "en
10-1> teat"ent seeking
EJ+ally distib+ted by ace
A"eican Psychiatic Ass!ciati!n' (iagn!stic and 4tatistical Man+al !. Mental (is!des (4M-D' 201,%
8/20/2019 Obesity and the Mind: A Chicken and Egg Problem?
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$inge Eating and (e/essi!n
Mac+s et al%' 188elch I Aga' 137adden et al%' 1,$!dy et al%' 13#+ehnel I 7adden' 13M+ssell et al%' 160
23
6
8
10
12
13
16
18
20
$inge eating
*!n binge-eating
$ec% &epression 'nventory
Wadden et al., 2002
8/20/2019 Obesity and the Mind: A Chicken and Egg Problem?
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F!!d Addicti!n
4i"ila sy"/t!"at!l!gy t! s+bstance de/endence
$ehai!al and ne+!/hysi!l!gical eidence
$ain K eni!n"ent inteacti!n
C!nnecti!n ?ith $E(
23> !. th!se ?ith FA did n!t hae $E(
Pealence: 11> t! 9>
#!ball AM' Clak MM' C!llaG!-Claell M' #ell!gg ' A"es &' Ebbet ' &!the #$% he elati!nshi/ a"!ng .!!d addicti!n' negatie "!!d' and
eating-dis!deed behai!s in /atients seeking t! hae baiatic s+gey% 4+g Obes Relat (is% 201 A/ 22% PM5(:2618,,02%
(O5:10%1016%s!ad%201%03%00%Mac+s MM' 7ildes E% (is!deed eating in !bese indiid+als% C+ O/in Psychiaty 2013' 29:33,-339%(O5:10%109LCO%000000000000010,
8/20/2019 Obesity and the Mind: A Chicken and Egg Problem?
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5"/act !n eat"ent
8/20/2019 Obesity and the Mind: A Chicken and Egg Problem?
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(e/essi!n and $aiatic 4+gey
22> t! > li.eti"e hist!y !. de/essi!n
30> !. /atients !n antide/essant
(e/essi!n d!es n!t al?ays es!le
)!ng-te" /!st!/eatie +se !. /sych!t!/ics
RL&$ "ay a..ect abs!/ti!n' distib+ti!n'
eli"inati!n
Risk .! /!! ?eight !+tc!"es
5ncease isk !. sel.-ha"
$hatti et al%' 201@)egenba+e et al%' 2012@ Mitchell et al%' 201,@ R!eig et al%' 2012@ 4te..en et al%' 2012
8/20/2019 Obesity and the Mind: A Chicken and Egg Problem?
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a+"a =ist!y
Attiti!n
5nceased distess
)!se less ?eight in $7)P EJ+ialent ?eight l!ss 2 yeas /!st s+gey
5nceased isk !. /sychiatic h!s/italiGati!ns
$+se et al%' 2003@ Clak et al%' 2009
8/20/2019 Obesity and the Mind: A Chicken and Egg Problem?
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F!!d Addicti!n I 7eight )!ss
FA elated t! less ?eight l!ss
a.te bie. $7)P
/!st-baiatic s+gey
FA n!t elated t! ?eight l!ss !+tc!"es
! attiti!n in $7)P
2 yeas /!st RL&$
$+"eiste et al%' 2012@ Clak I 4a+les' 201,@ #!ball et al%' 201@ )ent et al%' 201,
8/20/2019 Obesity and the Mind: A Chicken and Egg Problem?
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Alc!h!l and $aiatic 4+gey
#re-(p )ear " )ear 2
A;( 9%0> 9%> "0*+
Alc!h!l-elated ha" 6%1> 9%,> *.
Alc!h!l de/endence 2%6> ,%8> /*0
A;(5 8 2%3> ,%6> /*
#ing et al%' AMA 2012@,09:21-22
Pe!/ s% y 1 /N%2@ Pe!/ s L 2 / %001@ 1 y s 2 y /N%02
n N 1'3
8/20/2019 Obesity and the Mind: A Chicken and Egg Problem?
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1 2 , 3 6 8100
2
3
6
8
10
12
Swedish (bese Subjects
C!nt!l $anding H$& &$P
1ollow-up tie, year
#roportion of patients reporting ediu ris% alcohol consuption 34
Alc!h!l and $aiatic 4+gey
4enss!n et al%' 201, Obesity
8/20/2019 Obesity and the Mind: A Chicken and Egg Problem?
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4!+ce: he Obesity 4!ciety 5n.!ga/hic ask F!ce' *!e"be 201
8/20/2019 Obesity and the Mind: A Chicken and Egg Problem?
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y/ical (ietes )!ss&ain C!+se
5eight
6ie
8/20/2019 Obesity and the Mind: A Chicken and Egg Problem?
23/36©2016 MFMER | slide-2,
Obesity eat"ent
7ifestyle 8odification
(iet Physical Actiity $ehai! change
Medicati!ns .! ?eight l!ss
End!sc!/ic /!ced+es
5nceased
isks
A"!+nt !.?eight l!ss
10>
10-1>
1-20>
$aiatic s+gey 2-3>
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©2016 MFMER | slide-23
Expert panel report: Guidelines (2013) or the !ana"e!ent o o#er$ei"ht and obesity in adults.
Obesity 201% 22(&2): &%1'&%10
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©2016 MFMER | slide-2
$ehai!al 5nteenti!n
;sed intechangeably ?ith li.estyle inteenti!n
(iet
Physical actiity
$ehai! thea/y
echniJ+es t! e/lace "alada/tie behai!s?ith ne? eating and actiity habits
4a?e' &een' Hette' 7adden% $ehai! thea/y ?hee ae ?e n!?Q
C+ O/in End!cin!l (iabetes Obes 200@16:,39-,2%
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©2016 MFMER | slide-26
$ehai! hea/y .! Obesity
Self-onitoring
4ti"+l+sC!nt!l
4!cial4+//!t
Mind.+lEating
C!gnitieRest+ct+ing
&!al 4etting
7adden et al% irculation 2012
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©2016 MFMER | slide-29
$ake' Ray"!nd C%' and (aniel 4% #ischenba+"% 4el.-M!nit!ing May $e *ecessay .! 4+ccess.+l 7eight C!nt!l%Seha#ior *herapy 23' n!% , 1,D: ,99
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©2016 MFMER | slide-28
4el.-"!nit!ing
C!nsistent /edict! !. ?eight l!ss
Cal!ie intake +ndeesti"ated +/ t! 0>
=igh .eJ+ency K c!nsistency N "!e ?eight l!ss
Elect!nic t!!ls "ay be bette
F!!d' ?eight' /hysical actiity
$+ke )E' 7ang ' 4eick MA% 4el.-"!nit!ing in ?eight l!ss: A syste"atic eie? !. the liteat+e% A" (iet Ass!c 2011@111:2@ Petes!n et al%' Obesity 2013@22:162-169%
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©2016 MFMER | slide-2
5denti.y and Manage igges
Pe!/le
Places
i"es !. day
E"!ti!ns
4!cial eents
Cetain .!!ds
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©2016 MFMER | slide-,0
Challenge L!+ igges
A!id' li"it' ! "aste tiggest! stay !n tack
;se a .!!d diay ! !the
sel.-"!nit!ing deice ;se e?ads n!t .!!dTD
Mind.+lness a//!ach
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©2016 MFMER | slide-,1
O+tc!"es
7eight l!ss indicated and desied
)i.estyle inteenti!ns
8 kg in 6 "!nths U - 10>D
&eate than +s+al cae
Haiability
Expert panel report: Guidelines (2013) or the !ana"e!ent o o#er$ei"ht and obesity in adults. Obesity 201% 22(&2): &%1'&%10
4!+ce: ;C!nn R+dd Cente .! F!!d P!licy I Obesity
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©2016 MFMER | slide-,2
Relati!nshi/ $et?een Physical Actiity andMaintenance !. 7eight )!ss
*!t Maintained Maintained0
20
30
60
80
100
Subjects ;xercising 34
#ay"an 4' $+!ld 7' 4ten 4% Maintenance and ela/se a.te ?eight l!ss in ?!"en: behai!al as/ects% A! + lin ,utr 10@2:800-809%7yatt =' Catenacci HA% he !le !. /hysical actiity in /!d+cing and "aintaining ?eight l!ss% ,at lin Pract Endocrinol -etab 2009@,9D:18-2%
P0%001
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©2016 MFMER | slide-,,
4+""ay
Many /sych!l!gical as/ects t! eating and ?eight
(e/essi!n can lead t! !besity and ice esa
F! s!"e /e!/le' ?eight is /!tectie
4el.-"!nit!ing dietay intake is best /edict! !.
$ei"ht loss
Physical actiity is best /edict! !. $ei"ht loss
!aintenance
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©2016 MFMER | slide-,
7eight $ias
*egatie attit+des that negatiely in.l+ence
inteacti!ns
Obseed in childen' /aents' health cae
/!ides' "edia
A..ects e"/l!y"ent' ed+cati!n' health cae
4!cial' /sych!l!gical' /hysical c!nseJ+ences
4tig"atiGing ide!s ?ith !nline ne?s st!ies
htt/:???%+c!nn+ddcente%!g"edia-galley
P+hl et al% =eadless' h+ngy' and +nhealthy: A ide! c!ntent analysis !. !bses /es!ns /!tayed in !nline ne?s% +
ealth o!! 201,@0:1-19
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V+esti!ns I (isc+ssi!n