NUTRIGENOMICS, NUTRACEUTICS & LONGEVITY

1 F. MAROTTA, MD, PhD (Japan), 1 A. CAMPIOTTI, MD, 2 F. HE, PhD

1 ReGenera Research Group for Aging Intervention & Milano Medical - Healthy Aging Unit, Italy.

2 Dept. of Nutrition & Food Hygiene, West China School of Public Health, Sichuan University, China.

3° Annual International conference of Geriatrics & Gerontology Dept, Ain Shams University; "AgeING Friendly Globe”

herbal extracts (SC100) that are predicted to modulate the expression of many genes involved in aging and stress resistance

PLOS ONE, April 16, 2015

020406080

100120140160

0 1 month 2 months

Salivary Amylase: effect of AFA-based supplementation

Novel Aphanizomenon-based formulation® with wider adaptogenic and mood-enhancer ability

124 Female patients (40 pre-menopausal and 80 menopausal)• All with swinging mood, lack of energy and mental vigilance, • even if on HRT• Treatment: Adapto-MM 1c 2 times a day for 3 months• Benefit: subjective improvement of VAS already after 2-3 weeks

(p<0.001)• Reduced waking salivary cortisol leveò• Reduced oxidative stress and Revelar score and improved carotene

content

Milano Medical – Healthy Aging Center research team