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8/8/2019 Nurs-134 Medication Research Fa2010
1/15
Postpartum Medications - Mother
Name, dose, route,
frequency
Class, Action of drug
and why ordered for
this patient
Potential Side Effects Patient assessments
needed before
administering
How will you know this
drug is effective for this
patient
Patient teaching you
need to do
Ibuprofen (Motrin)
Doses:
400 mg q_4__ hours600 mg q_6___ hours
800 mg q_6___ hours
prn
Class:NSAID, nonopiate analgesic,
antipyretic
(Skidmore,487)
Action: Decreases Cox-1 and Cox-2 enzymes
necessary for
biosynthesis of
prostaglandin.
Analgesic, anti-
inflammatory,
antipyretic. (Skidmore,
487, Adams 726)
Why: Mild to moderatepain, inflammation.(Murray & Mckinney,
408)
The most common side
effects from ibuprofen
are GI related, which
include nausea, vomiting,diarrhea or constipation,
anorexia, and heartburn.
(Adams, 726)
*Assess current
medications being taken.
- oral anticoagulants are
taken d/t an increased risk
of bleeding
-Use with other NSAIDs
or corticosteroids may
increase risk of serious GI
symptoms
(Adams, 726)
*Assess for GI symptoms
such as nausea, vomiting,
or diarrhea (Murray &
McKinney, 408)
*Assess for infection-may
mask symptoms
(Skidmore, 488)
*pt will report a
reduction in pain within
one hour.
*A reduction in
inflammation or
temperature will be
noted.
(Adams, 726)
*Take PO with food or
milk. (Murray &
McKinney, 408)
*Advise pt to avoid
alcohol, salicylates,
and other NSAIDs r/t
an increased risk of GI
bleeding. (Skidmore,
488)
*Advise pt to notify
HCP of hematemesis,
tarry stools or coffee
ground vomit. (Adams,
726)
Acetaminophen (Tylenol)
325-500 mg po q 4-6 hours
prn
*Nonopioid analgesic,
antipyretic (Adams, 729)
*Inhibition of COX in
CNS; no peripheral nerve
action.
*Mild to moderate pain
(Murray & McKinney,408)
*Within recommended
dosing limits,
acetaminophen usually
produces few side effects.
(Adams, 730)
*May cause
hepatotoxicity withoverdose or long term use
(Skidmore, 38)
*Assess pts current drug
hx for any other Rx or
OTC meds that contain
acetaminophen to
calculate total dosing.
(Adams, 730)
*Assess patient for typicalalcohol use to avoid an
increased risk of
hepatotoxicity. (Adams,
730)
*Pt will report a
reduction in pain within
one hour. (Adams, 730)
*Do not take with
alcohol d/t increased
risk of liver damage.
(Adams, 730)
*Report any signs of
hepatotoxicity, such as
jaundice, yellowing ofeyes, clay-colored
stools, or dark urine.
(Adams, 730)
Oxycodone (Percolone)
5 mg. po q __4___hours
prn (Murray &
McKinney, 408)
* Opiate analgesic
(Skidmore, 718)
*Fill receptor mu and
kappa receptor sites in
CNS which blocks
*CNS sx-drowsiness,
dizziness, confusion,
H/A, sedation, euphoria.
*GI sx-nausea, vomiting,
anorexia, constipation,
*Assessment of pain on
scale.
*Assessment of VS, LOC,
allergies, and time of last
dose.
*Pt will report a
reduction in pain within
one hour. (Adams, 438)
*Inform HCP if pain
rating increases.
*Immediately report
SOB, dyspnea,
vomiting, dizziness
1st Year Nursing \NURS-134 TraditionalNURS-134 Medication Research FA2010.doc
1
8/8/2019 Nurs-134 Medication Research Fa2010
2/15
Postpartum Medications - Mother
Name, dose, route,
frequency
Class, Action of drug
and why ordered for
this patient
Potential Side Effects Patient assessments
needed before
administering
How will you know this
drug is effective for this
patient
Patient teaching you
need to do
afferent
neurotransmitters
conveying pain. (Adams,
438)*Moderate pain (Murray
& McKinney, 408)
cramps.
*Respiratory depression.
(Skidmore, 719)
(Adams, 438) upon standing.
*Make position
changes slowly.
(Adams, 439)
Oxycodone 5 mg. and
Acetaminophen 325 mg
(Percocet)
1-2 tablets po q 4-6 hours
prn
Docusate (Colace)
100 mg. po BID
*Laxative, emollient
(Skidmore, 324) Stool
softener (Adams,1030)
*Permits easier mixing offats and fluids in
intestines/fecal mass,
detergent like action
(Murray & McKinney
395)
*Prevention of
constipation in
postpartum period-
especially helpful for
patients with episiotomy.
(Murray &
McKinney,395; Adams,
1031)
*Anorexia, cramps,
diarrhea. (Skidmore,
325)
*Allergies, last BM *Pt will have a BM
usually within first 2-3
days postpartum.
(Murray & McKinney,395)
*Take tabs or caps
with 8oz of liquid on
an empty stomach for
better results.(Skidmore, 325)
*Discuss with pt that
adequate fluid
consumption and
ambulation is
necessary for adequate
bowel function.
(Skidmore, 325)
Glycerin/Witch Hazel
topical pads (Tucks)
*Hemorrhoidal astringent
*Astringent
*Temporary relief of
localized itching and
discomfort r/t
hemorrhoids.
(Drugs.com)
*Rectal bleeding
(drugs.com)
*Rectal bleeding
(drugs.com)
* Assess size of
hemorrhoids.
*Temporary relief of
localized itching and
discomfort r/t
hemorrhoids.
(Drugs.com)
*Instruct pt to clean
area with water before
use and do not reuse
pad after application.
(drugs.com)
1st Year Nursing \NURS-134 TraditionalNURS-134 Medication Research FA2010.doc
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Postpartum Medications - Mother
Name, dose, route,
frequency
Class, Action of drug
and why ordered for
this patient
Potential Side Effects Patient assessments
needed before
administering
How will you know this
drug is effective for this
patient
Patient teaching you
need to do
Hydrocortisone-pramoxine
topical (Proctofoam-HC)
q6 hours prn hemorrhoids
*Pramoxine-Anesthetic;
Hydrocortisone-
corticosteroid
*Promoxine-interfereswith pain signals to the
brain; hydrocortisone-
reduces chemicals in the
body that cause
inflammation.
*Used on rectal area for
relief of inflammation on
itchiness.
(drugs.com)
*Allergic reaction-
uticaria and dyspnea
*Blurred vision, H/A,
sore throat, burning andirritation at area of
application, rectal
bleeding.
(drugs.com)
*Assess pt hx for known
allergies to steroids or to
anesthetic agents
(drugs.com)
*Relief of rectal
inflammation and
itchiness
(drugs.com)
*Wash perineumbefore application.
Ferrous Sulfate
300-325 mg. po BID
*Hematinic
*Replaces iron stores in
red blood cells.
*Iron deficiency anemia
and prophylaxis in
pregnancy
(Skidmore, 403-404)
*GI sx: Nausea,
constipation, epigastricpain, black and red tarry
stools.
(Skidmore, 404)
*Baseline hemoglobin
studies (Skidmore, 404)
*Improvement of Hct,
Hgb, reticulocytes.
*Pt reports decreased
fatigue and weakness.
(Skidmore, 205)
*Less GI discomfort if
taken with meals.(Murray & McKinney,
671)
*Take with Vitamin C
for better absorption.
(Murray & McKinney,
671)
*Encourage dietary
intake of iron-
meat,dark green leafy
vegetables, beans,
eggs. (Skidmore, 405)*Increase water intake,
bulk and activity for
constipation before
laxative use.
(Skidmore, 405)
Ketorolac (Toradol)
15-30 mg IV q6 hours
10 mg po q 4-6 hours
*NSAID, nonopioid
analgesic.
*Decreases enzyme
necessary for
prostaglandin synthesis
*CNS-dizziness
*GI-nausea, flatulence,
diarrhea, GI bleeding
(Skidmore, 530-531)
*Increased effects of
*Review current
medications for
anticoagulant use (Murray
& McKinney, 408)
*Assess for hx of aspirin
*Pt will report a decrease
in pain. (Skidmore, 532)
*Take PO with food or
milk to decrease GI
discomfort. (Murray &
McKinney, 408)
*Notify HCP for
1st Year Nursing \NURS-134 TraditionalNURS-134 Medication Research FA2010.doc
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Postpartum Medications - Mother
Name, dose, route,
frequency
Class, Action of drug
and why ordered for
this patient
Potential Side Effects Patient assessments
needed before
administering
How will you know this
drug is effective for this
patient
Patient teaching you
need to do
in inflammation.
(Skidmore, 531)
*Mild to moderate pain.
(Murray & McKinney,408)
anticoagulants. (Murray
& McKinney, 408)
sensitivity.
*Monitor for location of
pain and ROM 1hr before
administration.(Skidmore, 532)
bleeding, bruising,
fatigue, malaise.
(Skidmore, 532)
Simethicone (Mylicon)
80 mg (chewable tablet)
po pc and bedtime prn gas
*Antiflatulent
*Lowers surface tension
of gas bubbles, and
disperses/prevents gas
pockets in GI system.
(Skidmore, 871)
*Flatulence and
abdominal distention.
(Murray & McKinney,
408)
*GI-nausea, vomiting,
abdominal craming,
diarrhea.
(Adams, 1021)
*Identify reason for
excess gas, assess bowel
sounds. (Skidmore, 871)
*Absence of flatulence.
(Skidmore, 871)
*Relief of distension.
(Murray & McKinney,
408)
*Encourage
ambulation. (Murray
& McKinney, 408)
*Take after meals and
HS. (Skidmore, 871)
Ondansentron (Zofran)
4 mg. IVPB q6h prn
*Antiemetic
*Blocks serotonin in
PNS, CNS, and small
intestine to prevent
nausea and vomiting.
(Skidmore, 707)
*Postoperative nausea
and vomiting.
(Murray & McKinney,
408)
*CNS-headache
*GI-diarrhea, abdominal
pain.
*Musculoskeletal pain,
shivering, urinary
retention, orthostatic
hypotension, flulike sx.
(Skidmore, 707; Adams,
1043.)
*Assess for absence of
nausea or vomiting before
administration.
(Skidmore, 707)
*Absence of nausea and
vomiting. (Skidmore,
707)
*Inform pt reason for
administering, and
expected result.
*Instruct pt to report
GI sx, changes in
respirations, rash or
irritation at injection
site.
(Skidmore, 708)
Diphenhydramine
(Benadryl) 25 mg. IVP
q 6h prn itching
*1st generation, non
selective antihistamine
*Competes with
histamine for H1-receptor
site in blood vessels, GI
and respiratory system to
decrease allergic
response.
(Skidmore, 315)
*Itching after epidural
*Dry mouth, dizziness,
drowsiness, headache,
nausea, vomiting,
thickened bronchial
secretions, urinary
retention.
(Murray & McKinney,
408; Adams, 1265)
*Assess respiratory
status-may cause
increased CNS
depression.
(Skidmore, 317)
*Absence of itching.
(Murray & McKinney,
408)
*Caution pt to request
assistance with
ambulation d/t
dizziness.
*Consult physician if
breastfeeding; may be
contraindicated.
(Skidmore, 316)
1st Year Nursing \NURS-134 TraditionalNURS-134 Medication Research FA2010.doc
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Postpartum Medications - Mother
Name, dose, route,
frequency
Class, Action of drug
and why ordered for
this patient
Potential Side Effects Patient assessments
needed before
administering
How will you know this
drug is effective for this
patient
Patient teaching you
need to do
opioids. (Murray &
McKinney, 408)
RhO(D) Immune Globulin(RhoGAM)
One standard dose
(300mcg) IM within
___72__hours after
delivery
*Concentratedimmunoglobins, for RBC
antigen Rho(D)
*Suppresses immune
reaction in the Rh-
negative mother to Rh-
positive antigen blood of
a newborn. Prevents
hemolytic disease in
future pregnancies.
*Prevention of immune
reaction to Rh antibodies,hemolytic disease.
(Murray & McKinney,
649)
*Local pain atintramuscular site
*Fever
(Murray & McKinney,
649)
*Blood typing of motherand cord blood.
Administer if mother is
Rh-negative and newborn
is positive, or if uncertain
of newborn type.
(Murray & McKinney,
649)
*Assess for previous
reactions to
immunizations and
previous immunizationswith this product.
(Skidmore, 838)
*Prevention oferythroblastosis fetalis in
subsequent deliveries.
(Skidmore, 838)
*Teach patient reasonfor RhoGAM
administration, how it
works, and need for
future administration
in Rh positive
deliveries.
(Skidmore, 838)
Rubella Virus Vaccine
Entire volume of single-
dose vial subcutaneously
*Attenuated live virus
vaccine
*Causes formation of
antibodies against the
rubella virus by
producing a modified,
not communicable
rubella infection.*Administered to
pregnant or postpartum
mothers whose antibody
screen does not show
immunity to rubella to
prevent rubella infection
and severe congenital
defects in subsequent
pregnancies.
(Murray & McKinney,
400)
*Transient stinging at
injection site
*Fever
*Lymphadenopathy
*Arthralgia
*Transient arthritis
(Murray & McKinney,400)
*Assess pt hx for
immunosupression,
sensitive to neomycin or
eggs, respiratory tract or
febrile infection, active
TB, or conditions that
affect bone marrow or
lymphatic system as
vaccine may be
contraindicated.
(Murray & McKinney,
400)
*Immunity to rubella
virus.
*Pt should be
cautioned to avoid
pregnancy for at least
4 weeks after
administration.
(Murray & McKinney,
400)
1st Year Nursing \NURS-134 TraditionalNURS-134 Medication Research FA2010.doc
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Labor and Delivery Medications - Mother
Name, dose, route,
frequency
Class, Action of drug
and Why ordered for
this patient
Potential Side Effects Patient assessments, i.e.,
V.S. or lab values
How will you know this
drug is effective for this
patient
Patient teaching you
need to do
Dinoprostone (Cervidil)
10 mg. vaginal insert
q12 hours x2
*Oxytocic, abortifacient.
(Skidmore, 313)
*Myometriumstimulation to stimulate
uterine contractions and
cervical dilation.
(Skidmore, 313)
*Cervical ripening, Labor
induction (Murray &
McKinney, 364)
*GI-nausea, vomiting,
diarrhea
*Leg cramps, jointswelling, headache.
(Skidmore, 314)
*Fetal bradycardia.
*Assess for fever after
administration.
*Assess dilatation,effacement, fetal heart
tones, hypertonous
contractions lasting
longer than one minute.
*Assess respiratory rate
and rhythm, BP and
pulse-notify physician
immediately for
abnormalities after
administration.
*Assess forhypersensitive reaction-
dyspnea, rash.
(Skidmore, 314)
*Cervical ripening,
progression of labor.
(Skidmore, 314)
*Explain purpose of
administration and
expected result.*Advise pt to remain
supine for 10-15
minutes after insertion
of suppository.
*Instruct to inform
nurse or physician
immediately for
contractions that last
longer than one
minute.
(Skidmore, 314)
Magnesium Sulfate
2 Grams/hour IV (for
woman with Gestational
HTN or PTL)
*Electrolyte,
anticonvulsant, laxative,
tocolytic.
(Skidmore, 581, Murray
& McKinney, 712)
*Increases osmotic
pressure, draws fluid into
colon; relaxes uterineactivity. (Skidmore, 581,
Murray & McKinney,
713)
*Management of
pregnancy HTN and
prevention of seizures;
tocolytic. (Murray &
McKinney, 713)
*Fluid overload,
electrolyte imbalances-
potential to cause
pulmonary edema and
cardiac dysrhythmias.
*Depression of deep
tendon reflexes
*Respiratory or cardiacdepression
*Lethargy, weakness,
visual blurring, H/A,
sensation of heat,
constipation.
*Reduced fetal heart rate,
fetal-neonatal hypotonia.
(Murray & McKinney,
712-714)
*Assess VS, heart and
lung sounds hourly
*Monitor I&O ratio
*Check bowel sounds
Q4-8 hrs
*Serum magnesium levels
*Electronic fetalmonitoring
(Murray & McKinney,
713-714)
*Absence of HTN related
seizures
*Inhibition of preterm
labor
(Murray & McKinney,
712-713)
*Explain to pt reason
for administration and
expected outcome.
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Labor and Delivery Medications - Mother
Name, dose, route,
frequency
Class, Action of drug
and Why ordered for
this patient
Potential Side Effects Patient assessments, i.e.,
V.S. or lab values
How will you know this
drug is effective for this
patient
Patient teaching you
need to do
Oxytocin (Pitocin)
__2-10____ milliunits/
minute
IV (to induce or augmentlabor)
*Oxytocic
*Synthetic hormone that
stimulates uterine smooth
muscle to illicit stronger,longer, more frequent
uterine contractions. Has
vasoactive and
antidiuretic properties.
*Induction or
augmentation of labor at
or near term.
(Murray &McKinney,
366)
*Adverse reactions may
occur d/t hypersensitivity
or overdose.
*Hypertonic uterineactivity leading to fetal
bradycardia or
tachycardia, reduced fetal
heart rate variability and
late decelerations.
*Impaired uterine blood
flow leading to fetal
asphyxia.
*Uterine rupture, abrutio
placentae, rapid birth
causing maternal or fetaltrauma, maternal fluid
retention, hypotension,
tachycardia, cardiac
dysrhythmias,
subarachnoid
hemorrhaging.
(Murray &McKinney,
366)
*Assess fetal heart rate
for at least 20 minutes
prior to administration to
identify reassuring ornonreassuring patterns,
*Perform Leopolds
maneuvers and/or vaginal
examination to verify
cephalic fetal
presentation.
-If fetal presentation is
not cephalic, notify
physician and do not
administer.
*Observer for effectivelabor pattern after
administration.
-Contractions q2-3
minutes, lasting 40-90
seconds at an intensity of
50-80 mm Hg.
-Observe for uterine
hypertonicity:
contractions occurring
less than 2 minutes apart,
rest interval shorter than
30 seconds, lasting longer
than 90-120 seconds each.
*Monitor fetal heart rate
for nonreassuring patterns
such as tachycardia,
bradycardia, decreased
variability or late
decelerations.
*If uterine hypertonicity
or nonreassuring fetal
heart patterns are
*Induction or progression
of labor.
(Murray &McKinney,
366)
*Advise patient that
contractions will
mimic menstrual
cramps and willincrease intensity.
(Skidmore, 722)
*Discuss with pt the
reason for
administration, and the
expected results.
(Skidmore, 722)
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Labor and Delivery Medications - Mother
Name, dose, route,
frequency
Class, Action of drug
and Why ordered for
this patient
Potential Side Effects Patient assessments, i.e.,
V.S. or lab values
How will you know this
drug is effective for this
patient
Patient teaching you
need to do
observed, d/c infusion,
increase rate of
nonadditive solution,
place mother on her sideand administer O2 mask
8-10 L/min; notify
physician.
(Murray
&McKinney,366)
Nalbuphine (Nubain)
5-10 mg IV q 3-4 hours
prn pain
*Opioid analgesic
*Inhibits ascending pain
pathways and alters pain
perception
*Analgesia/intrapartum
supplement for delivery
(Murray &McKinney,
344; Skidmore, 664)
*Respiratory depression,
rash, nausea, vomiting,
cramps, drowsiness,
dizziness, confusion,
H/A, sedation.(Skidmore, 664)
*Assess current
medications and hx-
contraindicated for
opiate-dependant pts and
may reverse analgesiceffects of some other
narcotics such as
meperidine.
(Murray &McKinney,
344)
*Assess pain before and
after administration.
*Monitor VS, especially
respiratory status.
*Monitor CNS changes-
LOC, dizziness,confusion, pupil reaction.
*Monitor for allergic
reaction such as rash and
uticaria.
(Skidmore, 664)
*Relief of pain and
pruritis r/t epidural
narcotics. (Murray
&McKinney, 344)
*Advise pt that
dizziness, drowsiness
and confusion are
common and they
should ask forassistance before
ambulating.
*Instruct pt to change
position slowly to
prevent orthostatic
hypotension.
*Discuss with the pt
reasons for
administering and the
expected results.
(Skidmore, 664)
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Labor and Delivery Medications - Mother
Name, dose, route,
frequency
Class, Action of drug
and Why ordered for
this patient
Potential Side Effects Patient assessments, i.e.,
V.S. or lab values
How will you know this
drug is effective for this
patient
Patient teaching you
need to do
Fentanyl ___6___mcg.
via epidual
*Opioid analgesic
*Inhibits CNS ascending
pain pathways, increases
pain threshold; binds toopiate receptors to alter
pain perception.
*Relief of pain, adjuct to
epidural anesthesia.
(Skidmore, 401)
*Respiratory depression,
bradycardia, cardiac and
respiratory arrest,
laryngospasm, musclerigidity.
(Skidmore, 402)
*Monitor respiratory
status for 24 hours
*Assess VS
*Assess pain rating
regularly
*Assess ROM
*Monitor for allergic
reaction
*Monitor for CNS
changes-LOC, pupil
reaction, dizziness,
drowsiness.
(Murray &McKinney,
342-343; Skidmore, 402)
*Pt will have a reduction
in pain within 10
minutes.
(Murray &McKinney,342; Skidmore, 402)
*Advise pt that
dizziness, drowsiness
and confusion are
common and theyshould ask for
assistance before
ambulating.
*Instruct pt to change
position slowly to
prevent orthostatic
hypotension.
*Discuss with the pt
reasons for
administering and the
expected results.
(Skidmore, 403)
3Ephedrine sulfate 25-50
mg IV push for
hypotension due to spinal
or epidural anesthesia
*Vasopressor,
bronchodilator, nasal
decongestant
*Acts on beta receptors
in heart to increase
contractility and HR, acts
on alpha-receptors in
blood vessels to cause
vasoconstriction.
(Skidmore, 365)*Correction of
hypotension r/t epidural
or subarachnoid block
(Murray & McKinney,
344)
*Tremors, anxiety,
anorexia, nausea,
vomiting
(Skidmore, 357)
*Monitor BP and pulse
q5min when
administering IV
*Monitor respiratory
function r/t
bronchodilator action
*Monitor for allergic
reaction and paradoxical
brochospasm
*Assess for paresthesiasand coldness or
extremities r/t reduced
peripheral blood flow
(Skidmore, 357)
*Increased B/P
(Skidmore, 357)
*Explain reason for
medication and
expected outcome.
Oxytocin (Pitocin)
___2___Units added to 1st
postpartum IV (to prevent
pp hemorrhage)
*Oxytocic
*Synthetic hormone that
stimulates uterine smooth
muscle to illicit stronger,
longer, more frequent
*Adverse reactions may
occur d/t hypersensitivity
or overdose.
*Uterine hypertonicity
*Hypotension,
*Monitor VS q15 mins or
follow postpartum agency
protocol.
*Monitor lochia color,
quantity and presence of
clots.
*No incidence of uterine
pp hemorrhage (Murray
& McKinney, 366)
*Explain reason for
administration and
expected outcome.
(Skidmore, 722)
1st Year Nursing \NURS-134 TraditionalNURS-134 Medication Research FA2010.doc
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Labor and Delivery Medications - Mother
Name, dose, route,
frequency
Class, Action of drug
and Why ordered for
this patient
Potential Side Effects Patient assessments, i.e.,
V.S. or lab values
How will you know this
drug is effective for this
patient
Patient teaching you
need to do
uterine contractions. Has
vasoactive and
antidiuretic properties.
*Maintance of uterinecontractility post partum
to control bleeding.
(Murray &McKinney,
366)
tachycardia, cardia
dysrhythmias,
subarachnoid
hemorrhage.(Murray & McKinney,
366)
-notify physician for
bright red lochia or large
clots
*Observe uterus forfirmness, height, and
deviation.
*Palpate uterus, and
massage until firm if it is
boggy.
*Monitor I&O and
auscultate breath sounds
to identify fluid retention.
*Assess for cramping.
(Murray & McKinney,
366)
Methylergonovine maleate
(Methergine) 0.2 mg
po/IM/IV q 2-5 hours
*Oxytocic
*Stimulates continuous
uterine contraction and
causes arterial
vasoconstriction.
*Prevention and tx of pp
hemorrhage r/t uterine
atony or subinvolution.
(Murray & McKinney,
733)
*Nausea, vomiting,
uterine cramping,
hypertension, dizziness,
H/A, dyspnea, chest pain
& palpitations, peripheral
ischema, uterine and GI
cramping.
(Murray & McKinney,
733)
*Assess B/P prior to
administration and
monitor per agency
protocol.
*Assess fundal tone;
check for nonphasic
contractions, relaxation or
severe cramping.
(Murray & McKinney,
733; Skidmore, 615)
*Uterine contraction and
involution.
*Progression of
involution.
(Murray & McKinney,
733)
*Discuss reason for
administration and
expected outcome.
*Advise pt not to
smoke d/t increased
vasoconstriction
(Murray & McKinney,
733)
Terbutaline sulfate
0.25 mg subcutaneously
(discuss off-label use as a
tocolytic, not as an asthma
medication)
*Selective Beta-agonist
*Stimulates beta-
adrenergic receptors in
sympathetic nervous
system which inhibits
uterine muscular activity
*Stop preterm labor and
reduce or stop hypertonic
uterine contractions.
(Murray & McKinney,
*Maternal and fetal
tachycardia, palpitations,
cardiac dysrhythmias,
chest pain, wide pulse
pressure
*Dyspnea, chest
discomfort
*Tremors, restlessness,
H/A, dizziness, weakness
*Hypokalemia,
*ECG, blood glucose and
electrolyte levels, and
urinalysis prior to
administration.
*Assess fetal heart rate
when drug is initiated and
at agency recommended
intervals.
*Assess maternal pulse,
B/P and respirations same
*Preterm labor is stopped
*Hypertonic uterine
contractions stopped
(Murray & McKinney,
713)
*Encourage pt to
empty bladder q 2hrs.
*S/S of preterm labor
to be aware of after
discharge
(Murray & McKinney,
713)
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Labor and Delivery Medications - Mother
Name, dose, route,
frequency
Class, Action of drug
and Why ordered for
this patient
Potential Side Effects Patient assessments, i.e.,
V.S. or lab values
How will you know this
drug is effective for this
patient
Patient teaching you
need to do
713; Skidmore hyperglycemia
*Nausea, vomiting,
reduced bowel motility
*Flushing, diaphoresis
(Murray & McKinney,
713)
interval as FHR
monitoring.
*Notify physician for side
effects: maternal HR>120 bpm, respirations
>24, dyspnea, pulmonary
edema, systolic BP< 80-
90 mm Hg, FHR >160.
*Report continued uterine
activity
*Encourage pt to empty
bladder q 2hrs
(Murray & McKinney,
713)
Carboprost tromethamine
(Hemabate)
100-250-mcg q 1.5-3.5
hours IM (abortifacient)
250 mcg q 15-30 minutes
IM (pp hemorrhage)
*Oxytocic, abortifacient
*Stimulates uterine
contractions
*Loss or fetus; decreased
pp bleeding
(Skidmore, 176)
*Fever, chills, nausea,
vomiting, diarrhea
(Skidmore, 176)
*Monitor B/P and pulse;
monitor for changes
indicative of hemorrhage.
*Monitor respiratory
status
*Notify physician for
contractions lasting
>1minute
*Assess for incomplete
abortion
(Skidmore, 177)
*Abortion of fetus within
approximately 16 hours.
*No incidence of pp
hemorrhage
(Skidmore, 176)
*Advise pt to report
abdominal cramps,
increased temp or
blood loss or foul-
smelling lochia.
(Skidmore, 176)
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Labor and Delivery Medications - Mother
Name, dose, route,
frequency
Class, Action of drug
and Why ordered for
this patient
Potential Side Effects Patient assessments, i.e.,
V.S. or lab values
How will you know this
drug is effective for this
patient
Patient teaching you
need to do
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Medications -Newborn
Name, dose, route,
frequency
Class, Action of drug
and Why ordered for
this infant
Potential Side Effects Patient assessments
needed before
administering
How will you know this
drug is effective for this
infant
Parent teaching you
need to do
Vitamin K
(Aquamephyton) 1 mg.
IM x1 within 1 hour ofbirth
*Fat soluble vitamin
*Promotes formation of
clotting factors
II(prothrombin), VII, IX,
X by the liver
*Provides vitamin K to
neonate who can not
synthesize it in the
intestines d/t absence of
intestinal flora;
prevention of
hemorrhagic disease of
the newborn.
(Murray & McKinney,501)
*Erythema, pain, edema
at site of injection
*Anaphylaxis, hemolysis,
hyperbilirubinemia
especially in preterm
infant or overdose
(Murray & McKinney,
501)
*May be delayed 1 hour
after birth to allow for
feeding and bonding
*Observe continuously
for any bruising or
bleeding
*Assess gestational age
for dosing
*Infant should be bathed
prior to administration
(Murray & McKinney,
501; Skidmore, 764)
*No incidence of
newborn hemorrhagic
disease.
(Murray & McKinney,
501)
*Educate parents
reason for
administration.(Murray & McKinney,
500)
Erythromycin eye
ointment to both eyes x1
within 1 hour of birth
*Antibiotic
*Inhibits protein
synthesis in bacteria
*Prophylaxis of
opthalmia neonatorum r/t
Neisseria gonorrhoeae
and Chlamydia
trachomatis **required
by law
(Murray & McKinney,
501)
*Burning, itching,
chemical conjunctivitis
lasting 24-48 hours.
(Murray & McKinney,
501)
*Cleanse eyes before
application
*Hold tube horizontally
when applying to avoid
injury
*Administer from inner
canthus to outer canthus
*Ointment may be wiped
from outer eye after 1
minute
(Murray & McKinney,
501)
*Prevention of opthalmia
neonatorum r/t Neisseria
gonorrhoeae and
Chlamydia trachomatis
*Educate parents
reason for
administration.
(Murray & McKinney,
500)
Hepatitis B vaccine
(Engerix-B)
10mcg/0.5 mL IM x1
*Vaccine
*Immunization against
hepatitis B infection
*prevention of Hep B in
exposed and unexposed
infants (Murray &
McKinney, 520)
*Pain or redness at
injection site
*Low-grade fever
(Murray & McKinney,
520)
*Obtain parental consent
*Bathe infant prior to
injections to prevent
contamination from
maternal blood
(Murray & McKinney,
520)
*Pt will not become
infected with Hepatitis B
(Murray & McKinney,
520)
*Parent teaching that
this vaccine will
prevent hep B
infection and infant
will need to receive a
series of 3 doses
(Murray & McKinney,
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Medications -Newborn
Name, dose, route,
frequency
Class, Action of drug
and Why ordered for
this infant
Potential Side Effects Patient assessments
needed before
administering
How will you know this
drug is effective for this
infant
Parent teaching you
need to do
520)
Hepatitis B ImmuneGlobulin (HBIG)
0.5 mL within _____
hours of birth
*Immune globulin
*Provides antibodies and
passive immunity to
hepatitis B
*Prophylaxis for infants
of hepatitis B surface
antigen-positive mothers
(Murray & McKinney,
521)
*Pain and tenderness atinjections site
*Uticaria, anaphylactic
reaction
(Murray & McKinney,
521)
*Maternal hepatitis Bantigen screening
*Bathe infant prior to
injections to prevent
contamination from
maternal blood
(Murray & McKinney,
521)
*Prevention of hepatitisB infection
(Murray & McKinney,
521)
*Parent teaching aboutreason for medication
and expected outcome.
(Murray & McKinney,
521)
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