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November 2007 BRC5 Bethesda
Variation database
» Use Ensembl Variation database schema
» Ancilliary database to ‘core’
» Perl API for programmatic access
» Biomart implementation for data mining
» Align reads to reference genome and call SNPs
November 2007 BRC5 Bethesda
More Anopheles gambiae genomes
» Sequencing of A. gambiae M & S forms complete
» M form (WashU GSC) 2,754,999 reads
» S form (JCVI) 2,714,217 reads
» Planned sequencing for 12 genome Anopheles cluster
November 2007 BRC5 Bethesda
SNP calling in A. gambiae S form
» Data from Ewen Kirkness (JCVI)
» 2.1 million potential SNPs