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Myelopoiesis and Reconstitutes Bone Marrow After 5 Flurouracil
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E abxdl wbl{ekkce~oid bh nlekm {bndea w~bjbyd{ jdlbwbod{o{
eai ~dkba{yoytyd{ nbad je~~bp ehyd~ 4*hlt~bt~ekol* eai
o~~eioeyoba*oaitkdi jdlb{tww~d{{oba
Cto*Hda Loebe,n,k,i,Y, _t*Fda Kcdae,k, _tc*Kcda` _ea`e
e Idwe~yjday bh Jdiokel ^d{de~kc, Jekme Jdjb~oel Cb{woyel,
Yeowdo >45, Yeopea
n Idwe~yjday bh Jdiokel ^d{de~kc eai Ditkeyoba, Yeowdo Xdyd~ea{
@dad~el Cb{woyel, Yeowdo 55>, Yeopeak@~eiteyd Oa{yoytyd bh [wb~y
Kbekcoa` [kodakd, Kcoad{d Ktlyt~d Taoxd~{oy, Yeowdo 555, Yeopea
i Idwe~yjday bh Jbldktle~ Noblb` eai Nobkcdjo{y~, Aeyobael Kcoeo
Taoxd~{oy, Kcoeo 877, Yeopea
^dkdoxdi 9 Ftad >779= ekkdwydi >> Bkybnd~ >779
En{y~eky
Ycd eoj bh yco{ {yti pe{ yb oaxd{yo`eyd ycd w~bjbyoba bh
jdlbwbod{o{ n ea ekyoxd wbl{ekkce~oid bh nlekm{bndea #W[N[/! Jt~oad
{wldda kdll{ pd~d kblldkydi h~bj OK^ jokd eai kbaioyobadi jdioe
#[KJ/ pe{ w~dwe~di
n oaktneyoa` ycd{d kdll{ poycbty W[N[ #ab~jel*[KJ/ b~ poyc W[N[
oa kbakday~eyoba{ ~ea`oa` h~bj 5>!4 yb 577
E`"jl #W[N[*[KJ/! Jt~oad nbad je~~bp kdll{ pd~d y~deydi poyc
W[N[ elbad b~ [KJ yb oaitkd ycd hb~jeyoba
bh kblbaod{, oakltioa` KHT*@J, KHT*@DJJ, NHT*D eai CWW*KHK! Ycd
kbakday~eyoba{ bh {os cdjeybwbodyok
`~bpyc hekyb~{ kbayeoadi oa [KJ pd~d jde{t~di t{oa` davjd*loamdi
ojjtabe{{e! Oa ycd loxd eaojel
dswd~ojday, W[N[ pe{ eijoao{yd~di b~ell yb ybyel nbi*o~~eioeydi
#YNO/ eai 4*hltb~bt~ekol #4*HT/*y~deydi jokd
yb e{{d{{ ycd ~dkba{yoytyoba bh nbad je~~bp ehyd~
jdlb{tww~d{{oba! W[N[*[KJ {yojtleydi KHT*@J, KHT*
@DJJ, NHT*D eai CWW*KHK kblba hb~jeyoba poyc 94!7, 4!7, 8!>
eai 8!8*hbli oak~de{d{, ~d{wdkyoxdl!
Cbpdxd~, adoycd~ W[N[ elbad ab~ ab~jel*[KJ cei {tkc e
kblba*{yojtleyoa` dhhdky! Oa W[N[*[KJ, ycd ldxdl{
bh OL*8, OL*50, @*K[H eai @J*K[H pd~d je~mdil oak~de{di, nty aby
ycb{d bh OL*; eai [KH! B~el
eijoao{y~eyoba bh W[N[ oa jokd aby bal ~d{yb~di ycd ldtmbkyd
kbtay{ ~ditkdi n YNO eai 4*HT y~deyjday ntyel{b daceakdi KHT*@J
kblba hb~jeyoba bh nbad je~~bp kdll{ poycbty e {o`aohokeay kcea`d
oa nbi pdo`cy!
77>9*;>74") * {dd h~bay jeyyd~I >774 Dl{dxod~ Oak! Ell
~o`cy{ ~d{d~xdi!
ibo657!5758"f!lh{!>779!57!737
Y Kb~~d{wbaioa` etycb~! Idwe~yjday bh Jbldktle~ Noblb` eai
Nobkcdjo{y~, Aeyobael Kcoeo Taoxd~{oy, ;77 Taoxd~{oy
^bei, Kcoeo 877, Yeopea! Ydl!6 -338 4 >350035= hes6 -338 4
>350037!
D*jeol eii~d{{6 loebchG{ddi!ady!yp #C!*H! Loeb/!
Lohd [kodakd{ 00 #>774/ 97795;
ppp!dl{dxod~!kbj"lbkeyd"lohd{kod
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8/9/2019 Novel Polysaccharide of Black Soybean Promotes
Myelopoiesis and Reconstitutes Bone Marrow After 5 Flurouracil
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Pd kbakltid ycey W[N[ w~bjbyd{ jdlbwbod{o{ ekyoxoy oa ycd nbad
je~~bp, {yojtleyd{ w~bitkyoba bh xe~obt{
cdjeybwbodyok `~bpyc hekyb~{ h~bj {wldda kdll{, eai
~dkba{yoytyd{ nbad je~~bp ycey ce{ ndda jdlb{tww~d{{di
n o~~eioeyoba eai 4*HT!
I >774 Dl{dxod~ Oak! Ell ~o`cy{ ~d{d~xdi!
Mdpb~i{6 Wbl{ekkce~oid bh nlekm {bndea #W[N[/= Jdlbwbod{o{=
[wldda kdll*kbaioyobadi jdiotj #[KJ/= Kblba hb~joa`
taoy #KHT/= 4*Hlt~bt~ekol= O~~eioeyoba
Oay~bitkyoba
Nlekm {bndea ]@lkoad jes #L!/ Jd~~!Z o{ e {bndea ktlyoxe~ poyc e
nlekm {ddi kbey! Oa y~eioyobael
Kcoad{d jdiokoad, nlekm {bndea ce{ ndda t{di hb~ idybsohokeyoba,
e{ ea eayo*oahlejjeyb~, eai ybojw~bxd ycd nlbbi! [bndea ce{ ndda
~dwb~ydi yb wb{{d{{ jea w~bwd~yod{, oakltioa` ojjtad
jbitleyoba #@lei{cdxe dy el!, >775/, oaconoyoba bh
ke~koab`dad{o{ #[tvtmo dy el!, >77>/, eayobsoieyoba
#Joadjbyb dy el!, >77>/, eai e kcbld{yd~bl lbpd~oa` dhhdky
#Md~kmcbhh{ dy el!, >77>/! Cbpdxd~, ycd~d e~d
hdpd~ ~dwb~y{ {wdkohokell kbakd~aoa` nlekm {bndea! Oy ce{ ndda
w~bxda ycey nlekm {bndea wb{{d{{d{ e
co`cd~ eayobsoieyoxd ekyoxoy ycea {bndea #_ea` dy el!, 5???/!
Pea` #5??>/ ~dwb~ydi ycey y~deyjday bh ;3
ldtmbwdaok weyoday{ poyc nlekm {bndea*kbayeoaoa` cd~nel
w~d{k~owyoba{ oak~de{di ycd atjnd~ bh
ko~ktleyoa` pcoyd nlbbi kdll{ #Pea`, 5??>/! Oa e w~dxobt{
{yti, pd hbtai ycey e co`c*jbldktle~ pdo`cy
wbl{ekkce~oid bh nlekm*{bndea #W[N[/ poyc ea e*loamdi `ltkea
{y~tkyt~d o{ ycd jefb~ kbjwbaday poyc
w~bxoioa` ojjtad ~d`tleyoba eai eayo*ytjb~ dhhdky{ #Loeb dy el!,
>775/! Bycd~ oaxd{yo`eyoba{ cexd el{b
idjba{y~eydi jea noblb`okel htakyoba{ bh wbl{ekkce~oid{ h~bj
aeyt~el w~bitky{! Hb~ dsejwld{,e
*loamdi `ltkea oa ~okd n~ea ce{ ndda w~bxda yb {yojtleyd
eayo*ytjb~ ojjtaoy #Meyeje dy el!, >77>=
@cbadtj eai Fdpdyy, >777/, eai c*loamdi `ltkea o{bleydi h~bj
jdiokoael hta`o o{ ~d{wba{onld hb~ ycdo~
ojjtabjbitleyoa` ekyoxoyod{ #Neb dy el!, >77>= Kcda dy
el!, 5??0= Pda` dy el!, >77>/!
Jdlb{tww~d{{oba ehyd~ ~eiobycd~ew b~ kcdjbycd~ew o{ e jefb~
lojoyoa` hekyb~ oa ycd kloaokel
y~deyjday bh keakd~{! Kbakt~~day kcdjb~eioeyoba o{ abp e
{yeaie~i y~deyjday hb~ lbkell eixeakdi
jelo`aeakod{ b~o`oaeyoa` h~bj ycd d{bwce`t{, {ybjekc, weak~de{,
kblb~dkyel, eat{, tyd~o kd~xos, dyk
#Cdaaoa` dy el!, >777= Joykcdll dy el!, >775/, eai, ycd
~d{tly{ e~d w~bjo{oa`, ycd {dxd~oy bh
jdlb{tww~d{{oba o{ `~deyd~ ycea ycey bh {oa`ld y~deyjday
jbieloy! Ycd~dhb~d, w~bjbyoba bh
cdjeybwbod{o{ ~djeoa{ ea dsy~djdl ojwb~yeay kcellda`d oa
kloaokel keakd~ y~deyjday!
Cdjeybwbodyok {ydj eai w~b`daoyb~ kdll{ oa ycd nbad je~~bp cexd
ycd enoloy yb {dlh*~dwlokeyd eai
iohhd~dayoeyd oayb jeyt~d nlbbi kdll{! Xe~obt{ cdjeybwbodyok
`~bpyc hekyb~{ #C@H{/ {yojtleyd ycd{dw~bkd{{d{, oakltioa`
`~eatlbkyd*jek~bwce`d #@J*K[H/, `~eatlbkyd #@*K[H/, eai jek~bwce`d
#J*
K[H/ kblba {yojtleyoa` hekyb~= oayd~ldtmoa #OL/*;= OL*8= eai
{ydj kdll hekyb~ #[KH/ #Kcda dy el!, 5??;=
Pea` dy el!, 5??5n/! [dxd~el wbydayoel i~t`{, {tkc e{
ab~keayce~oioa #AKYI/ eai E{y~e`elt{
wbl{ekkce~oid #EW[/, cexd ndda yd{ydi hb~ ycdo~ enoloy yb
ekyoxeyd kdll*jdioeydi ojjtaoy! Ycd{d
i~t`{ aby bal oaconoy ytjb~ `~bpyc #Kcda dy el!, >77>=
Wokmd~oa` dy el!, >77;/, nty el{b w~bjbyd
jdlbwbod{o{ #Pea`, 5?3?= Vct eai Vct, >775/!
Oa ycd w~d{day {yti, pd eyydjwydi yb kle~oh pcdycd~ W[N[
{yojtleyd{ {ydj eai w~b`daoyb~ kdll
w~blohd~eyoba io~dkyl b~ ekyoxeyd{ {wldda kdll{ yb {dk~dyd C@H{
yb w~bjbyd jdlbwbod{o{ n oa xoy~b e{{e!
Ycd dhhdky{ bh W[N[ ba ~dkba{yoytyoba bh nbad je~~bp oa
jdlbenleydi jokd pd~d el{b dsejoadi!
C!*H! Loeb dy el! " Lohd [kodakd{ 00 #>774/ 97795; 975
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Jeyd~oel{ eai jdycbi{
Jeyd~oel{ eai eaojel{
W[N[ pe{ wt~ohodi h~bj ea dsy~eky bh nlekm {b ndea yc~bt`c e
{d~od{ bh {dwe~eyoba w~bkdit~d{ e{
id{k~ondi oa bt~ w~dxobt{ ~dwb~y #Loeb dy el!, >775/! Oa
n~odh, lowoi*{bltnld eai lbp*jbldktld pdo`cy
kbjwbaday{ oa nlekm {bndea pd~d ~djbxdi t{oa` iokclb~bjdycead
eai dyceabl eai ycda dsy~ekydi n
peyd~ ey 073K! Ycd peyd~*{bltnld dsy~eky pe{ kblldkydi eai
idw~bydoaovdi poyc w~bydoae{d M! Ht~ycd~
{dwe~eyoba bh ycd aba*w~bydoa peyd~*{bltnld h~ekyoba pe{
wd~hb~jdi n loutoi kc~bjeyb`~ewc eai `dl
holy~eyoba, eai ycd ekyoxd W[N[, poyc e co`c jbldktle~ pdo`cy
pe{ o{bleydi!
Jeld OK^ jokd #57 yb 5> pddm{ bh e`d, ;4 H 4 `/, wt~kce{di
h~bj ycd Aeyobael Lenb~eyb~ Eaojel
N~ddioa` eai ^d{de~kc Kdayd~ #Yeowdo, Yeopea, ^BK/, pd~d mdwy
taid~ {wdkohok weycb`da*h~dd
kbaioyoba{! Ell dswd~ojday{ pd~d wd~hb~jdi oa ekkb~ieakd poyc
`toidload{ oa ycd AOC @toid hb~ ycd
Ke~d eai T{d bh Lenb~eyb~ Eaojel{ #ICC[ wtnlokeyoba Ab! AOC
34*>;, ~dxo{di 5??8/!
W~dwe~eyoba bh {wldabkyd*kbaioyobadi jdiotj #[KJ/
Ycd {wldda{ pd~d ~djbxdi h~bj ycd jokd, cbjb`daeydi oayb {oa ld
kdll{, eai io{wd~{di oayb
{t{wda{oba t{oa` e 5*jj jdyel {odxd! Ycd {wldda kdll{ #5 570
kdll{"jl/ pd~d ktlyt~di oa 57$ hdyel kelh
{d~tj #HK[/ kbayeoaoa` ^WJO 5897 jdiotj poycbty #ab~jel [KJ/ eai
poyc W[N[ ey kbakday~eyoba{ bh
5>!4, >4, 47, eai 577 E`"jl #W[N[*[KJ/ ey ;03K oa e htll
ctjoiohodi eyjb{wcd~d kbayeoaoa` 4$ KB>!
Ehyd~ 0> cbt~{, ycd {twd~aeyeay pe{ kblldkydi yb {d~xd e{
{wldabkyd*kbaioyobadi jdioe #[KJ/, {yd~olovdi
n holy~eyoba, eai {yb~di e{ 5*jl eloutby{ ey073K tayol t{d!
W~dwe~eyoba bh WCE*[KJ eai lta`*kbaioyobadi jdiotj #LKJ/ e{
wb{oyoxd kbay~bl
Wcybcdje``ltyoaoa W #WCE, 57 E`"jl= Iohkb Len!, Idy~boy, JO/ pe{
t{di yb w~dwe~d [KJ #WCE*
[KJ/ e{ enbxd id{k~ondi ycey {d~xdi e{ e wb{oyoxd kbay~bl!
Lta`*kbaioyobadi jdiotj #LKJ/ pe{
w~dwe~di e{ w~dxobt{ oaxd{yo`eyoba poyc jbiohokeyoba #Hdib~bkmb
dy el!, >77>/! Ycd lta` pe{ ~djbxdi
h~bj ycd jokd, klowwdi oayb wodkd{, eai ktlyt~di oa 57$ hdyel
kelh {d~tj #HK[/ kbayeoaoa` ^WJO 5897
jdiotj ey ;03K oaktneyb~! Ehyd~ 4 ie{, ycd {twd~aeyeay pe{
kblldkydi yb {d~xd e{ lta`*kbaioyobadi
jdiotj #LKJ/, {yd~olovdi n holy~eyoba, eai {yb~di e{ 5*jl
eloutby{ ey073K tayol t{d!
E{{e hb~ `~eatlbkyd*jek~bwce`d #KHT*@J/ kblba*hb~joa` kdll{
Kblba*hb~joa` taoy*`~eatlbkyd"jek~bwce`d #KHT*@J/ e{{e t{oa` e
{bhy*e`e~ ktlyt~d jdycbi
pe{ wd~hb~jdi hb~ eaelvoa` ycd `~eatlbkyd*jek~bwce`d
kblba*hb~joa` wbydayoel bh nbad je~~bp
{ydj kdll{ e{ w~dxobt{l id{k~ondi #Pea` dy el!, 5??8/! Nbad
je~~bp kdll{ kblldkydi h~bj OK^ jokd
pd~d ~d{t{wdaidi oa ^WJO 5897 jdiotj {twwldjdaydi poyc 57$ HK[
eai ktlyt~di hb~ ?7 joatyd{ ey
;03K oa e ctjoiohodi 4$ KB> oaktneyb~! Ycda, io{ke~i ycd
eicd~day kdll{, eai ycd cdjeybwbodyok {ydj
kdll{ dso{y oa ycd aba*eicd~day led~! Ycd aba*eicd~day nbad
je~~bp kdll{ #5 574 kdll{"jl/ pd~d ycda
wleydi oa e 5*jl led~ bh 7!;$ e`e~ #[o`je/ oa JkKb{ 4E jdiotj
{twwldjdaydi poyc 54$ HK[,
d{{dayoel eai aba*d{{dayoel ejoab ekoi{, xoyejoa K eai {biotj
w~txeyd! Dekc [KJ eai W[N[ elbad,
ell ey >7$ #x"x/, pe{ eiidi pcold wleyoa` ycd kdll{, poyc
dekc wleyd cexoa` ycd {ejd hoael kdll
C!*H! Loeb dy el! " Lohd [kodakd{ 00 #>774/ 97795;97>
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Myelopoiesis and Reconstitutes Bone Marrow After 5 Flurouracil
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kbakday~eyoba! Ehyd~ 0 ie{ bh oaktneyoba, ycd ybyel atjnd~ bh
kblbaod{ pe{ kbtaydi t{oa` ea oaxd~ydi
jok~b{kbwd #Bljwt{, Jdlxolld, A_/! Ycd jb~wcblb` bh ycd kblba
pe{ idyd~joadi oa {oyt ehyd~
hoseyoba poyc 4$ `ltye~elidcid, idci~eyoba poyc jdyceabl, eai
{yeoaoa` poyc Ce~~o{Y
cdjeybsloa#Pea` dy el!, 5??>/!
E{{e hb~ jtlyowbydayoel #KHT*@DJJ/ eai d~yc~boi #NHT*D/
kblba*hb~joa` kdll{
Kblba e{{e hb~ jtlyowbydayoel #kblba*hb~joa`
taoy*`~eatlbkyd"d~yc~bkyd"jek~bwce`d" jd`e*
me~bkyd, idabydi e{ KHT*@DJJ/ eai d~yc~boi #nt~{y*hb~joa`
taoy*d~yc~bkyd, idabydi e{ NHT*D/
kblba*hb~joa` kdll{ pd~d ke~~odi bty ekkb~ioa` yb w~bkdit~d{
w~dxobt{l id{k~ondi #[ta dy el!, >77;=
Lot dy el!, >77;n/! Ycd aba*eicd~day nbad je~~bp kdll{ #4
579/, ~okc bh cdjeybwbodyok {ydj kdll{, pd~d
wleydi oa ;4*jj ktlyt~d io{cd{ kbayeoaoa` e 5 jl josyt~d bh 5$
jdyclkdlltlb{d oa O{kbxd{ jbiohodi
Itlndkkb{ jdiotj #[ydjKdll Ydkcablb`od{, Xeakbtxd~, NK, Keaeie/,
;7$ HK[, 5$ nbxoad {d~tj
elntjoa, 7!5 jJ >*jd~kewybdyceabl, > jJ L*`ltyejoad, 5
taoy d~yc~bwbodyoa #DWB= Kbaaet`cyLenb~eyb~od{ Lyi,Pollbpield,
Baye~ob, Keaeie/, eai >7$ [KJ! Ycd io{cd{ pd~d oaktneydi ey ;03K
oa e
ctjoiohodi eyjb{wcd~d hlt{cdi poyc 4$ KB> hb~ 0 ie{! Kblbaod{
pd~d oidayohodi eai {kb~di poyc ea
oaxd~ydi jok~b{kbwd #577S/! KHT*@DJJ cei josdi kblbaod{
kbayeoaoa` `~eatlbkyd{ #@/,
d~yc~bkyd{ #D/, jbabkyd"jek~bwce`d{ #J/ eai jd`eme~bkyd{ #J/,
pcold NHT*D cei jtlyokday~ok
#nt~{y/ d~yc~boi kblbaod{ poyc e ~di b~ woam kblb~!
E{{e hb~ co`c w~blohd~eyoxd wbydayoel kblba*hb~joa` kdll{
#CWW*KHK/
OK^ jokd pd~d {oa`ld*nblt{ oafdkydi oay~ewd~oybadell #o!w!/ poyc
547 j`"m` nbi pdo`cy bh 4*
hlt~bt~ekol #4*HT= H! Cbhhjeaa*Le ^bkcd Lyi!, Ne{dl,
[poyvd~leai/ eai {ek~ohokdi ;7 cbt~{ leyd~ #Lot dyel!, >77;e/!
Bal ycd ~d{ydi {ydj kdll{, aejdi CWW*KHK, {t~xoxdi oa nbad je~~bp
ehyd~ jokd y~deydi
poyc co`c ib{d 4*HT! Nbad je~~bp kdll{ ~dkbxd~di h~bj ycd jokd
pd~d kbtaydi eai e{{edi hb~ kdll
kkld n hlbp kybjdy~ yb d{yojeyd ycd wd~kdaye`d bh kdll{ e~~d{ydi
oa @7"@5 wce{d! Ehyd~ pcokc, 574
kdll{ pd~d wleydi oa e`e~b{d ktlyt~d{ poyc b~ poycbty ea
eiioyoba bh 57$ #x"x/ jbt{d lta`*kbaioyobadi
jdiotj #LKJ/, {ojole~ yb ycd KHT*@J kblba*hb~joa` e{{e #Pea` dy
el!, 5??5e= Yojdt{ dy el!, >77;/!
Ycd w~blohd~eyoxd ekyoxoy bh ycd{d 4*HT*~d{o{yeay de~l {ye`d
{ydj eai w~b`daoyb~ kdll{ #CWW*KHK/ pe{
dsw~d{{di e{ ycd atjnd~ bh kblbaod{ ey ie 59!
Jde{t~djday bh kybmoad ldxdl{
Davjd*loamdi ojjtab*{b~nday e{{e #DLO[E/ moy{ pd~d wt~kce{di
h~bj ^(I [{ydj{ #Joaadew*blo{, JA/ hb~ e{{e bh kybmoad{! Ycd
kbakday~eyoba{ bh OL*;, 8, 50, [KH, @*K[H eai @J*K[H oa [KJ
kblldkydi ehyd~ ; ie{ oaktneyoba poyc xe~obt{ kbakday~eyoba{ bh
W[N[ pd~d jde{t~di! Ab~jel [KJ
pe{ t{di e{ e kbay~bl!
Ybyel nbi o~~eioeyoba eai W[N[ eijoao{y~eyoba oa xoxb
Yb dsejoad ycd dhhdky bh W[N[ ba jokd poyc ~eioeyoba*oaitkdi
jdlb{tww~d{{oba, ycd OK^ jokd
pd~d ioxoidi oayb hbt~ `~btw{ #8 jokd wd~ `~btw/6 #5/ tay~deydi
kbay~bl{, #>/ W[N[ elbad, #;/ ybyel
nbi o~~eioeyoba #YNO/ elbad, #9/ YNO wlt{ W[N[ eijoao{y~eyoba!
Hb~ YNO, ycd dayo~d nbi pe{
C!*H! Loeb dy el! " Lohd [kodakd{ 00 #>774/ 97795; 97;
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Myelopoiesis and Reconstitutes Bone Marrow After 5 Flurouracil
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o~~eioeydi oa e {oa`ld h~ekyoba poyc 3 @ #8 JdX wcbyba ndej/
t{oa` e loade~ ekkdld~eyb~ #Kloaek^
5377, Xe~oea E{{bkoeyd{, Oak!, KE, T[E, ib{d ~eyd >!9 @"joa/
ba ie 7! B~el eijoao{y~eyoba bh W[N[
#977 j`"m` nbi pdo`cy"ie/ pe{ {ye~ydi 8 cbt~{ ehyd~ YNO eai
kbayoatdi h~bj ie 7 yb 9! Oa ycdkbay~bl `~btw, jokd ~dkdoxdi ab~jel
{eload b~ell! Wd~owcd~el nlbbi pe{ kblldkydi h~bj ycd b~noyel
{oat{ ba ie{ 7, >, 9, 8, 3, 57, 5>, 59 eai 58, eai
ldtmbkyd{ pd~d kbtaydi t{oa` e Kbtlyd~ kbtayd~! Oa
eiioyoba, dekc jbt{d{ pdo`cy pe{ jde{t~di dxd~ bycd~ ie it~oa`
ycd dswd~ojdayel wd~obi! Ba ie
50, ycd jokd pd~d {ek~ohokdi eai nbad je~~bp kdll{ pd~d ~djbxdi
hb~ ea ds xoxb KHT*@J kblba*
hb~joa` e{{e!
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C!*H! Loeb dy el! " Lohd [kodakd{ 00 #>774/ 97795;979
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8/9/2019 Novel Polysaccharide of Black Soybean Promotes
Myelopoiesis and Reconstitutes Bone Marrow After 5 Flurouracil
a
6/14
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C!*H! Loeb dy el! " Lohd [kodakd{ 00 #>774/ 97795; 974
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8/9/2019 Novel Polysaccharide of Black Soybean Promotes
Myelopoiesis and Reconstitutes Bone Marrow After 5 Flurouracil
a
7/14
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C!*H! Loeb dy el! " Lohd [kodakd{ 00 #>774/ 97795;978
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8/9/2019 Novel Polysaccharide of Black Soybean Promotes
Myelopoiesis and Reconstitutes Bone Marrow After 5 Flurouracil
a
8/14
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C!*H! Loeb dy el! " Lohd [kodakd{ 00 #>774/ 97795; 970
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8/9/2019 Novel Polysaccharide of Black Soybean Promotes
Myelopoiesis and Reconstitutes Bone Marrow After 5 Flurouracil
a
9/14
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C!*H! Loeb dy el! " Lohd [kodakd{ 00 #>774/ 97795;973
-
8/9/2019 Novel Polysaccharide of Black Soybean Promotes
Myelopoiesis and Reconstitutes Bone Marrow After 5 Flurouracil
a
10/14
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C!*H! Loeb dy el! " Lohd [kodakd{ 00 #>774/ 97795; 97?
-
8/9/2019 Novel Polysaccharide of Black Soybean Promotes
Myelopoiesis and Reconstitutes Bone Marrow After 5 Flurouracil
a
11/14
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W[N[*[KJ oaitkdi jeyt~eyoba bh e n~bei {wdky~tj bh nlbbi kdll{
oakltioa` KHT*@J, KHT*@DJJ,
NHT*D eai CWW*KHK!
C@H kbayday oa W[N[*[KJ oakltidi ypb `~btw{ bh jbldktld{6
{yojtleyoa` hekyb~{ eai {ad~`ovoa`
hekyb~{! Pd hbtai ycey W[N[ {yojtleydi ycd {dk~dyoba bh OL*8,
OL*50, @*K[H eai @J*K[H! Yco{ oaiokeyd{
ycey nbyc {yojtleyoa` eai {ad~`ovoa` dhhdky{ e~d oaxblxdi oa ycd
W[N[*oaitkdi jdlbwbod{o{! OL*;, @*,
J*eai @J*K[H e~d jeoal cdjeybbwbodyok `~bpyc hekyb~{ ycey
{yojtleyd jdlboi kblba hb~jeyoba
io~dkyl! OL*8 eai [KH io~dkyl {twwb~y w~blohd~eyoba eai
iohhd~dayoeyoba bh bal e {jell atjnd~ bh jt~oadcdjeybwbodyok kdll{
#Xe~atj*Hoaad dy el!, >77;= Peicpe dy el!, >77;/, nty ycd eky
{ad~`o{yokell poyc
@*, J*eai @J*K[H yb daceakd ycd ybyel atjnd~ bh kblbaod{ #Jtdakc
dy el!, 5??>= Ke~ekkoblb dy el!,
5?3?/! OL*50, e abxdl kybmoad w~bitkdi n ekyoxeydi ecYK^-KI9KI3Y
kdll{, oaitkd{ {y~bjel kdll{
yb {dk~dyd kybmoad{ oaxblxdi oa w~b*oahlejjeyoba eai
cdjeybwbod{o{ #[kcpe~vdand~`d~ eai Mbll{,
>77>/! [dxd~el e~yokld{ oaiokeydi ycey OL*50 oak~de{di
`~eatlbwbod{o{ oa ldtmbkyd eicd{oba jbldktld*
idhokoday jokd #Hb~lbp dy el!, >775/ eai ~d`tleydi KHT*@J eai
NHT*D w~b`daoyb~{ oa ab~jel eai wb{y*
o~~eioeydi jt~oad nbad je~~bp #Fbxkok dy el!, >775/! Ycd
{o`aeloa` jdkceao{j bh OL*50 oaxblxd{
y~b{oad wcb{wcb~leyoba bh {dxd~el jdjnd~{ bh ycd FEM eai [YEY
w~bydoa{ #[tn~ejeaoej dy el!, 5???/!
Ht~ycd~jb~d, Jdyc*E kdll{ y~ea{hdkydi poyc ycd cOL*50 `dad kea
oaitkd ytjb~*{wdkohok eayoytjb~
ojjtaoy n et`jdayoa` ycd dsw~d{{oba bh JCK kle{{ O eai OO
eayo`da{ #Co~ece~e dy el!, >775/! Pd e~d
`boa` yb yd{y dekc jEn e`eoa{y OL*50, OL*8, @*K[H eai @J*K[H,
eai xe~obt{ jEn kbjnoaeyoba{ ybkle~oh pcokc C@H o{ w~dibjoaeay!
Ycd ~de{ba W[N[ heoldi yb {yojtleyd ycd w~bitkyoba bh [KH eai
OL*; ~djeoa{ yb nd dltkoieydi! Bad
wb{{onoloy o{ ycd lekm bh ~dkdwyb~{ hb~ W[N[ ba kdll{ ycey
w~bitkd [KH b~ OL*;! Eabycd~ wb{{onoloy o{ ycd
w~d{dakd bh W[N[*oaitkdi oaconoyb~{ bh [KH eai OL*; w~bitkyoba!
Ab~jel kdll{, {tkc e{ jbabatklde~
kdll{, KI;9- kdll{, jdlbnle{y{, dyk, {dk~dyd atjd~bt{ `~bpyc
hekyb~{, kybmoad{ eai kcdjbmoad{ ycey
hb~j ycd ne{o{ bh oayd~kdlltle~ k~b{{*yelm adypb~m{ eai ~d`tleyd
ycd xe~obt{ {ye`d{ bh cdjeybwbod{o{
#Jefme dy el!, >775/! Bt~ {yti {cbpdi ycey C@H kbayeoadi oa
W[N[*[KJ ekydi poyc DWB eai LKJ yb
hb~j NHT*D eai CWW*KHK kblbaod{! Yco{ {t``d{y{ ycey jdlbwbod{o{
o{ oa heky e kbjwlds w~bkd{{
oaxblxoa` e xe~ody bh ~d`tleyb~ jbldktld{, ey lde{y {bjd bh
pcokc e~d oaitkdi n W[N[!
C!*H! Loeb dy el! " Lohd [kodakd{ 00 #>774/ 97795;957
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8/9/2019 Novel Polysaccharide of Black Soybean Promotes
Myelopoiesis and Reconstitutes Bone Marrow After 5 Flurouracil
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[dxd~el kloaokel y~oel{ cexd {cbpa ycey oafdkyoba bh @*K[H b~
@J*K[H {o`aohokeayl oak~de{d{ ycd
atjnd~ bh adty~bwcol{ eai jbabkyd{ oa weyoday{ poyc
cdjeybwbodyok cwbhtakyoba, {tkc e{ ycey {dda oa
ewle{yok eadjoe #@oabwbtlb{ dy el!, >77>/, oiobweycok
adty~bwdaoe #[tlyeae dy el!, >77;/, eai d{wdkoell oakeakd~
weyoday{ hbllbpoa` y~deyjday poyc kybybsok i~t`{ #[eakcdv dy el!,
>77>= Kd{e~b dy el!, >77;/! Ycd
heky ycey W[N[ {y~ba`l w~bjbyd{ jdlbwbod{o{ nty ce{ lbp
kybybsokoy jemd{ W[N[ oy ea eyy~ekyoxd
keaioieyd hb~ kloaokel yd{yoa`, d{wdkoell oa keakd~ weyoday{ pcb
bhyda idxdlbw {dxd~d adty~bwdaoe ehyd~
co`c*ib{d kcdjbycd~ew #Mojt~e eai Bmtie, 5???= Xe~xd~o{ dy el!,
>77;/ b~ ~eiobycd~ew #Kelid~bao dy
el!, >77>/! W[N[ je el{b wbydayoeyd @*K[H*oaitkdi
jbnoloveyoba bh {ydj kdll{ eai yct{ nd t{dhtl oa
wd~owcd~el nlbbi {ydj kdll y~ea{wleayeyoba! Ycd w~bjbyoba bh
jdlbwbod{o{ n W[N[ o{ utoyd iohhd~day
h~bj ycey bh ~dkbjnoaeay @*K[H! W[N[ ekyoxeyd{ ojjtabkbjwdyday
kdll{ yb {dk~dyd daib`dabt{ C@H!
@*K[H o{ bal bad e~j bh ycd C@H {{ydj, nty W[N[ ewwde~{ yb
{yojtleyd ycd dayo~d {{ydj!
Eiioyobaell, pcold ~dkbjnoaeay @*K[H o{ e{{bkoeydi poyc eixd~{d
dhhdky{, oakltioa` jt{kld eai nbad
weoa, cdeiekcd, hdxd~, heyo`td eai aet{de, W[N[ o{ jtkc ld{{
ybsok!
W[N[ yct{ o{ e aeyt~el w~bitky ycey poyc co`c {ehdy eai {yenoloy
ycey w~bjbyd{ jdlbwbod{o{ nbyc oaxoy~b eai oa xoxb #oa ea eaojel
jbidl/! Pd e~d da`e`di oa e ht~ycd~ oa xoxb eaojel {yti t{oa` e
ytjb~
ojwleayeyoba jbidl yb bn{d~xd ycd dhhdky{ bh W[N[ ba oaconoyoa`
ytjb~ `~bpyc eai w~bjbyoa`
jdlbwbod{o{ ehyd~ ~eioeyoba*eai kcdjbycd~ew*oaitkdi nbad je~~bp
{tww~d{{oba!
Ekmabpldi`jday{
Yco{ pb~m{ pe{ {twwb~ydi n e ~d{de~kc `~eay A[K
?>*>;55*N*5?4*77> h~bj ycd Aeyobael [kodakd
Kbtakol bh ycd ^dwtnlok bh Kcoae eai e `~eay X@C ;00*5 h~bj ycd
Xdyd~ea{ @dad~el Cb{woyel, Yeowdo,
Yeopea! Ycd etycb~{ pbtli lomd yb yceam W~bh! [cda`*_tea Pea`
#Idwe~yjday bh Jdiokel ^d{de~kc eai
Ditkeyoba, Xdyd~ea{ @dad~el Cb{woyel, Yeowdo, Yeopea/ hb~
cdlwhtl eixokd eai k~oyokel ~dxo{el bh ycd
jeat{k~owy!
^dhd~dakd{
Neb, S!H!, Vcda, _!, ^tea, L!, Hea`, F!A!, >77>!
Wt~ohokeyoba, kce~ekyd~oveyoba, eai jbiohokeyoba bh Y
ljwcbkyd*{yojtleyoa`
wbl{ekkce~oid h~bj {wb~d{ bh @eabid~je ltkoitj! Kcdjokel eai
Wce~jekdtyokel Ntlldyoa 47 #4/, 8>;8>?!
Kelid~bao, E!, xba N~odl, K!, Edno, [!, [bldayceld~, J!,
Ndyyokcd~, I!K!, >77>! Oayda{oxd kcdjbycd~ew poyc pcbld nlbbi
{ydj*
kdll {twwb~y eai kbakt~~day kcd{y ~eiobycd~ew oa {jell kdll lta`
keakd~6 e wce{d O"OO y~oel! Lta` Keakd~ ;8 #;/, ;>5;>8!
Ke~ekkoblb, I!, Kle~m, [!K!, ^bxd~e, @!, 5?3?! Ctjea
oayd~ldtmoa*8 {twwb~y{ `~eatlbkyok iohhd~dayoeyoba bh
cdjeybwbodyok
w~b`daoyb~ kdll{ eai eky{ {ad~`o{yokell poyc @J*K[H! Nlbbi 0;
#;/, 888807!Kd{e~b, [!, Kcoadllb, W!, Id [olxd{y~b, @!, Je~{ba, W!,
Wokkb, @!, Xe~byyb, [!, Woyyelo{, [!, Vead{kb, L!, >77;!
@~eatlbkyd
y~ea{ht{oba{ h~bj @*K[H*{yojtleydi ibab~{ hb~ ycd y~deyjday bh
{dxd~d oahdkyoba{ oa adty~bwdaok wdioey~ok weyoday{ poyc
bakb*cdjeyblb`okel io{de{d{! [twwb~yoxd Ke~d oa Keakd~ 55
#>/, 575578!
Kcda, _!F!, [coeb, J![!, Ldd, [![!, Pea`, [!_!, 5??0! Dhhdky bh
Kb~ikdw{ {oada{o{ ba ycd w~blohd~eyoba eai iohhd~dayoeyoba bh
ctjea ldtmdjok T?;0 kdll{! Lohd [kodakd{ 87 #>4/,
>;9?>;4?!
Kcda, _!A!, Kcda, F!K!, _oa, [!K!, Pea`, @![!, Y{etd~, P!, C{t,
[!H!, C{t, [!L!, >77>! Dhhdkyb~ jdkceao{j{ bh
ab~keayce~oioa*
oaitkdi joybyok e~~d{y eai ewbwyb{o{ oa ctjea cdweybje kdll{!
Oayd~aeyobael Fbt~ael bh Keakd~ 577 #>/, 543584!
Kcda, _!^!, C{t, J!L!, Cb, K!M!, Pea`, [!_!, 5??;! Kdll {bt~kd
eai noblb`okel kce~ekyd~o{yok{ bh jt~oad nbad je~~bp*id~oxdi
kblba*w~bjbyoa` ekyoxoy! Dswd~ojdayel Cdjeyblb` >5 #?/,
5>5?5>>8!
Hdib~bkmb, W!, D`di, E!, Xekdm, E!, >77>! O~~eioeyoba
oaitkd{ oak~de{di w~bitkyoba bh cedjbwbodyok eai w~boahlejjeyb~
kybmoad{ oa ycd jbt{d lta`! Oayd~aeyobael Fbt~ael bh ^eioeyoba
Noblb` 03 #9/, ;74;5;!
C!*H! Loeb dy el! " Lohd [kodakd{ 00 #>774/ 97795; 955
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8/9/2019 Novel Polysaccharide of Black Soybean Promotes
Myelopoiesis and Reconstitutes Bone Marrow After 5 Flurouracil
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Hb~lbp, [!N!, [kct~~, F!^!, Mbll{, F!M!, Ne`n, @!F!,
[kcpe~vdand~`d~, W!B!, Ld, M!, >775! Oak~de{di `~eatlbwbod{o{
yc~bt`c
oayd~ldtmoa*50 eai `~eatlbkyd kblba*{yojtleyoa` hekyb~ oa
ldtmbkyd eicd{oba jbldktld*idhokoday jokd! Nlbbi ?3 #5>/,
;;7?;;59!
@cbadtj, J!, Fdpdyy, E!, >777! W~bitkyoba bh ytjb~ adk~b{o{
hekyb~*elwce eai oayd~hd~ba*`ejje h~bj ctjea wd~owcd~el
nlbbiljwcbkyd{ n J@A*;, e jbiohodi e~enoabslea h~bj ~okd n~ea, eai
oy{ {ad~` poyc oayd~ldtmoa*> oa xoy~b! Keakd~
Idydkyoba eai W~dxdayoba >9 #9/, ;59;>9!
@oabwbtlb{, W!, Mbaybjeablo{, D!, Me~iejemo{, I!, [bt`ld~o, J!,
^eycb{o{, [!, Me~eae, E!, Kc~o{yoe{, C!, Jeaidllb{, @!, >77>!
E
wce{d OO {yti bh aba*wleyoatj ne{di kcdjbycd~ew poyc wekloyesdl
eai xoab~dlnoad oa aba*{jell kdll lta` keakd~! Lta`
Keakd~ ;3 #>/, 5??>7;!
@lei{cdxe, O!W!, Jb~bv, A!E!, Me~jembxe, Y!E!, Adjy{bxe, D!^!,
_emtnbx{mee, ^!O!, Le~obabxe, A!O!, >775! Ojjtabkbaft*
`eyd{ bh {bndea Nbpjea*No~m w~byde{d oaconoyb~ e{ ye~`dydi
eayoytjb~ wbljd~ok e`day{! Fbt~ael bh I~t` Ye~`dyoa` ? #4/,
;7;;58!
Cdaaoa`, @!Y!, [kcoli, [!D!, [yehhb~i, [!L!, Ibabctd, F!C!,
Nt~kc, W!E!, Ceiibkm, J!@!, @taid~{ba, L!L!, >777! ^d{tly{
bh
o~~eioeyoba b~ kcdjbo~~eioeyoba hb~ w~oje~ ta~d{dkyenld, lbkell
~dkt~~day, b~ `~b{{l oakbjwldyd ~d{dkyoba bh `e{y~ok
eidabke~koabje! Oayd~aeyobael Fbt~ael bh ^eioeyoba Bakblb`,
Noblb`, Wc{ok{ 98 #;/, 57?553!
Co~ece~e, A!, Aob, _!, [e{emo, [!, Joae~o, _!, Yemejt~e, J!,
O`tkco, K!, Iba`, J!, _eje{epe, M!, Yejt~e, M!, >775!
Oabktleyobabh ctjea oayd~ldtmoa*50 `dad*y~ea{hdkydi Jdyc*E
hon~b{e~kbje kdll{ oaitkd{ Y kdll*idwdaiday ytjb~*{wdkohok ojjtaoy
oa
jokd! Bakblb` 85 #5/, 0?3?!
Fbxkok, @!, Nt`e~{mo, I!, Wdyembx, J!, [yeambxok, F!,
[ybfeabxok, A!, Joldambxok, W!, >775! Dhhdky bh OL*50 ba oa
xoy~b
cdjeybwbodyok w~b`daoyb~ kdll{ `~bpyc eai kybmoad ~dlde{d oa
ab~jel eai wb{y*o~~eioeydi jt~oad nbad je~~bp! @~bpyc
Hekyb~{ 5? #5/, 8505!
Meyeje, J!, _b{cojo, A!, _ejeie, _!, [emeye, M!, Mtab, Y!,
_b{coie, M!, Uoeb, V!, Xoca, W!U!, Ope{emo, Y!, Mbnee{co, C!,
Jb~o, C!, >77>! W~dxdayoxd dhhdky bh hd~jdaydi n~bpa ~okd
eai ~okd n~ea e`eoa{y kblba ke~koab`dad{o{ oa jeld H;99 ~ey{!
Bakblb` ^dwb~y{ ? #9/, 3503>>!
Md~kmcbhh{, I!E!, N~bta{, H!, Cb~a{y~e, @!, Jda{oam, ^!W!,
>77>! Dhhdky{ ba ycd ctjea {d~tj lowbw~bydoa w~bhold bh
ndye*`ltkea,
{b w~bydoa eai o{bhlexbad{, wleay {yd~bl{ eai {yeabl{, `e~lok
eai ybkby~odabl{! Fbt~ael bh Aty~oyoba 5;> #?/,
>9?9>474!
Mojt~e, _!, Bmtie, C!, 5???! W~dxdayoba n kcoyb{ea bh
jdlbybsokoy, `e{y~boayd{yoael ybsokoy eai ojjtabkbjwdyday
b~`eaok
ybsokoy oaitkdi n 4*hltb~bt~ekol poycbty lb{{ bh eayoytjb~
ekyoxoy oa jokd! Fewead{d Fbt~ael bh Keakd~ ^d{de~kc ?7 #0/,
084009!Loeb, C!H!, Kcbt, K!F!, Pt, [!C!, Mcbb, M!C!, Kcda, K!H!,
Pea`, [!_!, >775! O{bleyoba eai kce~ekyd~oveyoba bh ea
ekyoxd
kbjwbtai h~bj nlekm {bndea ]@lkoad jes #L!/ Jd~~!Z eai oy{
dhhdky ba w~blohd~eyoba eai iohhd~dayoeyoba bh ctjea ldtmdjok
T?;0 kdll{! Eayo*Keakd~ I~t`{ 5> #57/, 395398!
Lot, N!, [ta, _!, Foea`, H!, Vcea , [!, Pt, _!, Lea, _!, _ea`,
S!, Jeb, A!, >77;e! Io{~twyoba bh [jei4 `dad ldei{
yb daceakdi w~blohd~eyoba bh co`c*w~blohd~eyoxd wbydayoel
w~dkt~{b~{ it~oa` djn~baok cdjeybwbod{o{! Nlbbi 575 #5/,
5>95;;!
Lot, D!, Fdloadm, F!, We{yb~d, _!I!, @tea, _!, W~kcel, F!H!,
W~kcel, F!Y!, >77;n! Io{k~ojoaeyoba bh wblkycdjoe{ eai
yc~bjnbkyb{d{ n abxdl, {ojwld, ekkt~eyd klbaeloy e{{e{ eai
kbjwe~o{ba poyc W^X*5 dsw~d{{oba eai NHT*D ~d{wba{d yb
d~yc~bwbodyoa! Nlbbi 575 #3/, ;>?9 ;;75!
Jefme, J!, Feabp{me*Podkvb~dm, E!, ^eyefkvem, F!, Dc~dajea, M!,
Wody~vmbp{mo, V!, Mbpel{me, J!E!, @dpo~yv, E!J!, Djd~{ba,
[!@!, ^eyefkvem, J!V!, >775! Atjd~bt{ `~bpyc hekyb~{,
kybmoad{, eai kcdjbmoad{ e~d {dk~dydi n ctjea KI;9- kdll{,
jdlbnle{y{, d~yc~bnle{y{, eai jd`eme~bnle{y{ eai ~d`tleyd ab~jel
cdjeybwbod{o{ oa ea etybk~oad"we~ek~oad jeaad~! Nlbbi?0 #57/,
;704;734!
Jdktkko, K!, Ke{{ojea, F!F!, xea id~ [kctd~da, N!,
Idpblh*Wddyd~{, K!, Heloao, N!, xea ida Nd~`cd, C!, 5?38!
Wcybcdje``ltyoaoa*kbaioyobadi jdiotj jbitleyd{ eicd~dakd
w~bwd~yod{ eai jb~wcblb` bh ceo~ kdll{! Ldtmdjoe
^d{de~kc 57 #?/, 57?557??!
Joadjbyb, _!, Hea`, S!, Cemejeye, M!, Peyeaend, _!, Eiekco, [!,
Mbjdyeao, Y!, Jey{tab, ^!, >77>! Bsoieyoba bh loabldok
ekoi
dakew{tleydi poyc {bltnld {bndea wbl{ekkce~oid n {w~e*i~oa`!
Nob{kodakd, Nobydkcablb` eai Nobkcdjo{y~ 88 #?/,
53>?53;9!
Joykcdll, [!D!, Jdaidacell, P!J!, Vlbydkmo, ^!E!, Ke~~bll, ^!^!,
>775! [utejbt{ kdll ke~koabje bh ycd eael keael!
Oayd~aeyobael
Fbt~ael bh ^eioeyoba Bakblb`, Noblb`, Wc{ok{ 9? #9/,
5770575;!
Jtdakc, J!B!, [kcadoid~, F!@!, Jbb~d, J!E
![AMPK activation inhibits the functions of myeloid-derived ... · progeroid mice [63]. The inflammaging process also af-fects the bone marrow which might induce aberrant myelopoiesis](https://img.dokumen.tips/doc/110x75/5d62a1b088c9934d418bdbe7/ampk-activation-inhibits-the-functions-of-myeloid-derived-progeroid-mice.jpg)
