NKU Department of Chemistry

Research Publications 2003-Present

NKU Faculty Member

*Undergraduate Researcher

2016 K. Cahill*; R. Suttmiller*; M. Oehrle*; A. Sabelhaus*; K. L. Gemene “Pulsed Chronopotentiometric Detection of Thrombin Activity Using Reversible Polyion Selective Electrodes,” Electroanalysis, 2017, 29, 448-455. DOI: 10.1002/elan.201600401

NKU Chemistry Publications 2003-Present Page 2 of 15

2016 E. Hofmann*; J. Webster*; T. Do*; R. Kline*; L. Snider*; Q. Hauser*; G. Higginbottom; A. Campbell; L. Ma; S. Paula “Hydroxylated chalcones with dual properties: Xanthine oxidase inhibitors and radical scavengers,” Bioorganic & Medicinal Chemistry, 2016, 24, 578-587. DOI: 10.1016/j.bmc.2015.12.024 K. L. Gemene “The Need for Synthetic Anticoagulants/Antidotes and Simple, Inexpensive and Reliable Sensors for These Biological Polyions,” Journal Research Analytical, 2016, 2, e102. L. Survant*; M. Andrejevic; J. Picker; J. Van den Hoeck; E. Fossum; I. Lagadic “Surface-initiated polymerization of styrene from one-step prepared thiol-functionalized organoclays,” Polyhedron, 2016, 114, 37-41. DOI: 10.1016/j.poly.2015.09.027

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2015 R. Shaheen; G. M. Abdel-Salam; M. P. Guy; R. Alomar; M. S. Abdel-Hamid; H. H. Afifi; S. I. Ismail; B. A. Emam; E. M. Phizicky; F. S. Alkuraya “Mutation in WDR4 impairs tRNA m(7)G46 methylation and causes a distinct form of microcephalic primordial dwarfism,” Genome Biology, 2015, 16, 210. DOI: 10.1186/s13059-015-0779-x PMID: 26416026 M. P. Guy; M. Shaw; C. L. Weiner*; L. Hobson; Z. Stark; K. Rose; V. M. Kalscheuer; J. Gecz; E. M.

Phizicky “Defects in tRNA Anticodon Loop 2'-O-Methylation are Implicated in Non-Syndromic X-

Linked Intellectual Disability Due to Mutations in FTSJ1,” Human Mutation, 2015, 36, 1176-1187.

DOI: 10.1002/humu.22897 PMID: 26310293

T. Dunn*; T. Do*; Q. Hauser*; K. C. Russell; L. Ma “A rapid one-step synthesis of isoflavanone compounds under microwave irradiation,” Current Microwave Chemistry, 2015, 2, 150-158. DOI: 10.2174/2213335602666141217222452 C. A. Basinger*; K. Sullivan*; S. Siemer*; S. A. Oehrle; K. A. Walters “Synthesis and preliminary characterization of a PPE-type polymer containing substituted fullerenes and transition metal ligation sites,” Journal of Chemistry, 2015, Article ID 672654. DOI: 10.1155/2015/672654

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2014

E. Amato*; T. Bankemper*; R. Kidney*; T. Do*; A. Onate*; F. S. Thowfeik; E. J. Merino; S. Paula;

L. Ma “Investigation of fluorinated and bifunctionalized 3-phenylchroman-4-one (isoflavanone)

aromatase inhibitors,” Bioorganic & Medicinal Chemistry, 2014, 22, 126–134.

DOI: 10.1016/j.bmc.2013.11.045

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2013

E. A. Walsh*; J. R. Deye*; W. Baas*; K. Sullivan*; A. Lancaster*; K. A. Walters “Synthesis and Spectroscopy of New Transition-Metal Fullerene Supramolecular Systems,” Journal of Photochemistry and Photobiology A, 2013, 260, 24-36. DOI: 10.1016/j.jphotochem.2013.03.006 R. Hemmer*; A. Hall*; R. Spaulding*; B. Rossow*; M. Hester*; M. Caroway*; A. Haskamp*; S. Wall*; H. A. Bullen; C. A. Morris; K. L. Haik “Analysis of Biotinylated Generation 4 Poly(amidoamine) (PAMAM) Dendrimer Distribution in the Rat Brain and Toxicity in a Cellular Model of the Blood-Brain Barrier,” Molecules, 2013, 18, 11537-11552. DOI: 10.3390/molecules180911537

K. Y. Chan*; B. Courtois*; K. Loose*; Hare, P. M. “Solvent dependent fluorescence lifetimes of estrone, 17β-estradiol, and 17α-ethinylestradiol,” Photochemistry and Photobiology, 2013, 2, 294-299. DOI: 10.1111/php.12011

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2012

K. L. Gemene; M. E. Meyerhoff “Selectivity enhancement for chloride ion by In(III)-porphyrin-based polymeric membrane electrode operated in pulsed chronopotentiometric mode,” Electroanalysis, 2012, 24, 643-648. DOI: 10.1002/elan.201200021 K. Y. Chan*; B. M. Gavaghan*; A. W. Stoeckel*; K. Irizarry*; P. M. Hare “Solvent effects on the steady state photophysics of estrone and 17β-estradiol,” Photochemistry and Photobiology, 2012, 88, 295-303. DOI: 10.1111/j.1751-1097.2011.01066.x C. H. Schein; D. Chen; L. Ma; J. J. Kanalas; J. Gao; M. E. Jimenez; L. E. Sower; M. A. Walter; S. R.

Gilbertson; J. W. Peterson “Pharmacophore Selection and Redesign of Non-nucleotide Inhibitors

of Anthrax Edema Factor,” Toxins, 2012, 4, 1288-1300.

DOI: 10.3390/toxins4111288

D. Chen; L. Ma; J. J. Kanalas; J. Gao; J. Pawlik; M. E. Jimenez; M. A. Walter; J. W. Peterson; S. R.

Gilbertson; C. H. Schein “Structure-based redesign of an edema toxin inhibitor,” Bioorganic &

Medicinal Chemistry, 2012, 20, 368-376.

DOI: 10.1016/j.bmc.2011.10.091

K. Bonfield*; E. Amato*; A. Bankemper*; H. Agard*; J. Steller*; J. Keeler*; D. Roy*; A. McCallum*;

S. Paula; L. Ma “Development of a new class of aromatase inhibitors: design, synthesis and

inhibitory activity of 3-phenylchroman-4-one (isoflavanone) derivatives,” Bioorganic and

Medicinal Chemistry, 2012, 20, 2603-2613.

DOI: 10.1016/j.bmc.2012.02.042

C. A. Cason*; T. A. Fabre*; A. Buhrlage; K. L. Haik; H. A. Bullen “Low-level Detection of

poly(amidoamine) PAMAM Dendrimers using lmmunoimaging Scanning Probe Microscopy,”

International Journal of Analytical Chemistry, 2012, 2012. 1-8. Article ID 341260

DOI: 10.1155/2012/341260

H. A. Bullen “Student-driven independent research projects: developing a framework for success

in analytical chemistry,” Analytical and Bioanalytical Chemistry, 2012, 404, 927-930.

DOI: 10.1007/s00216-012-6153-x

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2011

C. Elam*; M. Lape*; J. Deye*; J. Zultowsky; D. Stanton; S. Paula “Discovery of novel SERCA

inhibitors by virtual screening of a large compound library,” European Journal of Medicinal

Chemistry, 2011, 46, 1512-1523.

DOI: 10.1016/j.ejmech.2011.01.069 PMID: 21353727

H. A. Bullen; R. Hemmer; A. Haskamp*; C. Cason*; S. Wall*; R. Spaulding*; B. Rossow*; M.

Hester*; M. Caroway*; K. L. Haik “Evaluation of Biotinylated PAMAM Dendrimer Toxicity in

Models of the Blood Brain Barrier: A Biophysical and Cellular Approach,” Journal of Biomaterials

and Nanobiotechnology, 2011, 2, 485-493. [Invited Special Issue: Recent Advances in Drug

Delivery Systems]

DOI: 10.4236/jbnb.2011.225059

C. Larive; T. Wenzel; H. A. Bullen; R. S. Kelly; A. Fitch; A. Cavinato; E. Gross “Environmental

Analysis: Lake Nakuru Flamingos,” Journal of the Analytical Sciences Digital Library, 2011.

(http://www.asdlib.org/lakeNakuru.php)

K. Haik; H. A Bullen “A Risky Proposition? Undergraduate Research with Low-Income, First-

Generation, Underrepresented STEM Students,” CUR Quarterly, 2011, Spring.

J. N. Richardson; A. L. Drake*; C. E. Lazo-Miller*; D. W. Wolfe*; J. Hand*; T. Morgan*; I. L. Lagadic

“Lead Detection in Environmental Water using an Organoclay Film-based Attenuated Total

Reflectance Sensor,” Sensors & Actuators B, 2011, 158, 271-277.

DOI: 10.1016/j.snb.2011.06.018

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2010

P. M. Hare; E. A. Price; C. M. Stanisky; I. Janik; D. M. Bartels “Solvated electron extinction

coefficient and oscillator strength in high temperature water,” Journal of Physical Chemistry A,

2010, 114, 1766.

DOI: 10.1021/jp909789b

M. Lape*; C. Elam*; S. Paula “Comparison of current docking tools for the simulation of inhibitor

binding by the transmembrane domain of the sarco/endoplasmic reticulum calcium ATPase,”

Biophysical Chemistry, 2010, 150, 88-97.

DOI: 10.1016/j.bpc.2010.01.011 PMID: 20167416

M. Lape*; S. Paula; W. J. Ball, Jr. “A molecular model for cocaine binding by the

immunotherapeutic human/mouse chimeric monoclonal antibody 2E2,” European Journal of

Medicinal Chemistry, 2010, 45, 2291-2298.

DOI: 10.1016/j.ejmech.2010.02.004 PMID: 20185210

K. Haik; H. A. Bullen “Undergraduate Research at the Intersection of Disciplines: Challenges and

Solutions to Research Issues at the Interface of Biology and Chemistry at Northem Kentucky

University (NKU),” CUR Quarterly, 2010, Winter.

H. J. Gulley-Stahl*; P.A. Hogan II*; W. L. Schmidt*; S. J. Wall*; A. Buhrlage*; H. A. Bullen “Surface

Complexation of Catechol to Metal Oxides: An ATR-FTIR, Adsorption, and Dissolution Study,”

Environmental Science & Technology, 2010, 44, 4166-4121.

DOI: 10.1021/es902040u

E. D. Banks*; N. M. Taylor*; J. Gulley; B. R. Lubbers; J. G. Giarrizo; H. A. Bullen; T . M. Hoehler; H.

A. Barton “Bacterial Calcium Carbonate Precipitation in Cave Environments: A Function of

Calcium Homeostasis,” Geomicrobiology Journal, 2010, 27, 444-454.

DOI: 10.1080/01490450903485136

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2009

S. Paula; J. Abell*; J. Deye*; C. Elam*; M. Lape*; J. Purnell*; R. Ratliff*; K. Sebastian*; J. Zultowsky;

R. J. Kempton “Design, synthesis, and biological evaluation of hydroquinone derivatives as novel

inhibitors of the sarco/endoplasmic reticulum calcium ATPase,” Bioorganic and Medicinal

Chemistry, 2009, 17, 6613-6619.

DOI: 10.1016/j.bmc.2009.07.075 PMID: 19699645

J. Deye*; C. Elam*; M. Lape*; R. Ratliff*; K. Evans*; S. Paula “Structure-based virtual screening

for novel inhibitors of the sarco/endoplasmic reticulum calcium ATPase and their experimental

evaluation,” Bioorganic and Medicinal Chemistry, 2009, 17, 1353-1360.

DOI: 10.1016/j.bmc.2008.12.010 PMID: 19117760

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2008

C. A. Cason*; S. A. Oehrle; T. A. Fabré*; C. D. Girten*; K. A. Walters; D. A. Tomalia; K. H. Martines; H. A. Bullen “Improved Methodology for Monitoring Poly(amidoamine) Dendrimers Surface Transformations and Product Quality by Ultra Performance Liquid Chromatography,” Journal of Nanomaterials, 2008, Article ID 456082. DOI: 10.1155/2008/456082 M. G. Lauer*; J. W. Leslie*; A. Mynar*; S. A. Stamper*; A. D. Martinez*; A. J. Bray*; S. Negassi*; K. McDonald*; E. Ferraris*; A. Muzny*; S. McAvoy*; E. Wang; B. Nuez; C. Parish; K. A. Walters; K. C. Russell “Synthesis, Spectroscopy, and Theoretical Calculations for a Series of Push-Pull [14]-pyridoannulenes,” Journal of Organic Chemistry, 2008, 73, 474-484. DOI: 10.1021/jo7019724 J. R. Deye*; A. N. Shiveley*; S. A. Oehrle; K. A. Walters “Separation of Substituted Fullerenes using Normal-Phase HPLC-MS,” Journal of Chromatography A, 2008, 1181, 159-161. DOI: 10.1021/ic7018555 H. A. Bullen; K. A. Walters “Development of a Nanomaterials One-Week Intersession Course,” Journal of Chemical Education, 2008, 85, 1406-1409. DOI: 10.1021/ed085p1406 J. R. Deye*; A. N. Shiveley*; S. M. Goins*; L. Rizzo*; S. A. Oehrle; K. A. Walters “Synthesis of a New Ligand for Transition-Metal Fullerene Supramolecular Systems,” Inorganic Chemistry, 2008, 47, 23-25. DOI: 10.1016/j.chroma.2007.12.052

M. Lape*; C. Elam*; M. Versluis*; R. Kempton; S. Paula “Molecular determinants of sarco/

endoplasmic reticulum calcium ATPase inhibition by hydroquinone-based compounds,” Proteins:

Structure, Function, and Bioinformatics, 2008, 70, 639-649.

DOI: 10.1002/prot.21542 PMID: 17879345

H. J. Gulley-Stahl*; W. L. Schmidt*; H. A. Bullen “Characterization and Reactivity of Chromia Nanoparticles prepared by Urea Forced Hydrolysis,” Journal of Material Science, 2008, 43, 7066-7072. DOI: 10.1007/s10853-008-3056-5 C. Morris*; B. J. Sieve; H. A. Bullen “E-Learning Module: Introduction to X-ray Diffraction,” Journal of the Analytical Science Digital Library, 2008, Article ID 100047. (http://www.asdlib.org/onlineArticles/ecourseware/Bullen_XRD/XRDModule_index.htm)

NKU Chemistry Publications 2003-Present Page 11 of 15

J. Nordling; R. L. Millen; H. A. Bullen; M. Tondra; M. Granger; M. D. Porter “Giant Magnetoresistance Sensors: 1. Internally Calibrated Readout of Scanned Magnetic Arrays,” Analytical Chemistry, 2008, 80, 7930-7939. DOI: 10.1021/ac8009577 R. L. Millen; J. Nordling; H. A. Bullen; M. Tondra; M. Granger; M. D. Porter “Giant Magnetoresistive Sensors: 2. Detection of Biorecognition vents at Self-Referencing and Magnetically Tagged Arrays,” Analytical Chemistry, 2008, 80, 7940-7946. DOI: 10.1021/ac800967t H. A. Bullen; S. A. Oehrle; A. F. Bennett*; N. M. Taylor*; H. A. Barton “The Use of Attenuated Total Reflectance Fourier Transformed Infrared (ATR-FTIR) Spectroscopy to Identify Microbial Metabolic Products on Carbonate Mineral Surfaces,” Applications in Environmental Microbiology, 2008, 74, 4553. DOI: 10.1128/AEM.02936-07

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2007

J. H. Niewahner; K. A. Walters “Laboratory Instruction of an Experiment Using a Glove Box: Synthesis of Bis(1,2-dimethylimidazole)copper(I) hexafluorophosphate,” Journal of Chemical Education, 2007, 84, 702-703. DOI: 10.1021/ed084p702 J. H. Niewahner; K. A. Walters; A. Wagner* “Improved Synthesis of Geodken’s Macrocycle and the Synthesis of its Dichloride Salt,” Journal of Chemical Education, 2007, 84, 477-479. DOI: 10.1021/ed084p477 J. R. Deye*; K. A. Walters “Photoluminescence and Electroluminescence, Solid State,” in Application of Physical Methods to Inorganic and Bioinorganic Chemistry, R. A. Scott and C. M. Lukehart (Editors), John Wiley & Sons, 2007, 461-468. D. Stanton; J. Ankenbauer*; D. Rothgeb*; M. Draper*; S. Paula “Identification and characterization of novel sodium/potassium-ATPase inhibitors by virtual screening of a compound database,” Bioorganic and Medicinal Chemistry, 2007, 15, 6062-6070. DOI: 10.1016/j.bmc.2007.06.050 PMID: 17618121 R. A. Wilson*; H. A. Bullen “Learning Module: Introduction to Scanning Probe Microscopy,” Journal of the Analytical Sciences Digital Library, 2007, Article ID 100043. (http://www.asdlib.org/onlineArticles/ecourseware/Bullen/SPMModule.htm) H. A. Bullen “Teaching surface characterization to undergraduates,” Analytical and Bioanalytical Chemistry, 2007, 387, 1579-1581. DOI: 10.1007/s00216-006-1096-8

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2005 S. M. Keenan; R. K. Delisle; W. J. Ball; S. Paula; W. J. Welsh “Elucidation of the Na+, K+-ATPase digitalis binding site,” Journal of Molecular Graphics and Modeling, 2005, 23, 465-475. DOI: 10.1016/j.jmgm.2005.02.001 PMID: 15886034 S. Paula; M. R. Tabet; W. J. Ball, Jr. “Interactions between cardiac glycosides and sodium/ potassium-ATPase: 3D structure-activity relationship models for ligand binding to the E2-Pi form of the enzyme versus activity inhibition,” Biochemistry, 2005, 44, 498-510. DOI: 10.1021/bi048680w PMID: 15641774

M. E. Bardgett; P. J. Schultheis, P. J.; D. L. McGill; R. E. Richmond; J. R. Wagge* “Magnesium

deficiency impairs fear conditioning in mice,” Brain Research, 2005, 1038, 100-106.

DOI: 10.1016/j.brainres.2005.01.020

E. Ferraris*; D. L. McGill “Studies of an Engineered H+,K+ ATPase/Na+K+ATPase Chimeric Enzyme Expressed in HeLa Cells,” Norse Scientist, 2005, 3, 35-40.

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2004

P. J. Schulthies; T. J. Hagen; K. K. O'Toole*; A. Tachibana; C. R. Burke*; D. L. McGill; G. W. Okunade;

G. E. Shull “Characterization of the P5 subfamily of P-type transport ATPases in mice,”

Biochemical Biophysical Research Communications, 2004, 323, 731-738.

DOI: 10.1016/j.bbrc.2004.08.156 D. L. McGill “Double-Dipping as a Means of Creating Research Time,” CUR Quarterly, 2004, 24, 176.

NKU Chemistry Publications 2003-Present Page 15 of 15

2003 K. A. Walters; Y. J. Kim; J. T. Hupp “Manipulation of the Distance of Light-Induced Electron Transfer Within a Semi-Rigid Donor(Amine)/Acceptor(Terpyridine) Assembly via Complexation of Di-positive and Tri-positive Metal Ions,” Journal of Electroanalytical Chemistry, 2003, 554-555, 449-458. DOI: 10.1016/S0022-0728(03)00315-2 K. A. Walters “Stark Spectroscopy,” in Comprehensive Coordination Chemistry II, T. J. Meyer and J. A. McCleverty (Editors), Eleviser, 2003, Volume 2, 303-313.