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NES/ASAP Pharmacy Vocational Training SchemeSpecialist module
Infection and Antimicrobial Stewardship
Stage 3Resources 11th May 2014 v1.8
1
Please note that, with the exception of text books, the majority of resources within these lists will be available free of charge. Those which require either free registration or require a fee to be paid are annotated accordingly.
It is assumed that all participants will have registered with The Knowledge Network (TKN) and will have an Athens Password. Some of the URL links for such resources will link you direct to the article once you have entered your Athens password - if this fails, you should be able to access the article yourself via TKN.
Articles from the Journal of Antimicrobial Chemotherapy are available on the BSAC website or via TKN
There are a few resources listed which are on the YouTube platform and may not be accessible from NHS premises. These may require to be viewed from home or on a personal electronic device.
For webinars and videos the approximate running time is given in brackets after the name of the presentation
We would welcome your feedback - please contact NES Pharmacy if you have any comments about these resources or if you have trouble accessing any of the key resources.
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Contents Page number
BibliographySuggested texts - to be used for background knowledge as available locally for appropriate elements
5
Element 1 Introduction to Antimicrobial Stewardship Core resources
7
Element 2 Essential microbiology, resistance and basic immune function
11
Element 3 Antimicrobial agents by therapeutic class 15
Element 4 Healthcare Acquired Infection (HAI) 17
Element 5 Sepsis Diagnosis and Management 21
Element 6 Acute respiratory tract infection incorporating pneumonia and COPD
23
Element 7 - Urinary tract infection (UTI) 26
Element 8 Skin and soft tissue infection (SSTI) 29
Element 9 Surgical infection & prophylaxis 33
Element 10 Pharmacokinetics (PK) pharmacodynamics (PD) and therapeutic drug monitoring (TDM)
35
Element 11 Data analysis and presentation Incorporating interpretation of audit data
39
Element 12 Meningitis and CNS Infection 41
Element 13 Endocarditis and Cardiovascular Infection 44
Element 14 Bone & Joint Infections 46
3
Element 15 Gastrointestinal (GI) infections 48
Element 16 - Antibiotics used in pregnancy, neonates and paediatrics
51
Element 17 Sexually transmitted infection (STI), human immunodeficiency virus (HIV) & other blood borne virus (BBV)
56
Element 18 Tropical infectious diseases 62
Element 19 Chronic respiratory tract infections - tuberculosis (TB), cystic fibrosis (CF) and non-CF bronchiectasis
65
Element 20 Fungal infections 68
Element 21 Outpatient parenteral antimicrobial therapy (OPAT) 70
4
BibliographySuggested texts - to be used for background knowledge as available locally for appropriate elements
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
210 Antimicrobial Chemotherapy 6th Ed 2012 if available Oxford University Press
Finch RG
219 Sanford Guide 2013 if available Antimicrobial Therapy Inc
Gilbert et al (Eds)
http://www.sanfordguide.com/
296 Manual of Clinical microbiology 9th Ed 2007 (on TKN) ASM press Murray PR et al https://www.123library.org/bookdetails/?id=2814
299 Reese & Betts' practical approach to infectious diseases 5th Ed 2003 (on TKN)
Lippincott Williams and Wilkins
Betts RF et al http://www.knowledge.scot.nhs.uk/home/library/books/books-results.aspx?q=ctitle:(string(%22reese%22%2c+mode%3d%22and%22)+and+string(%22betts%22%2c+mode%3d%22and%22))&pm=fql&title=reese+and+betts&srt=rptitle100sub50bod20
329 Kucers' The Use of Antibiotics 6th Ed if available ASM Press & Hodder Arnold
Grayson ML
330 Principles and Practice of Infectious Diseases 7th Ed if available
Elsevier Churchill Livingstone
Mandell GL et al
292 Notes on medical Microbiology 4th Ed 2002 if available Churchill Livingstone Timbury MC et al
293 Clinical bacteriology 2003 if available Manson Publishing Struthers JK et al
384 Infection and Immunity 3rd Ed 2008 or 4th Ed 2013 if available
Oxford University Press
Playfair J Bancroft G
385 Basic & Clinical Immunology if available Churchill Livingstone Peakman M Vergani D
374 British National Formulary (BNF) BMJ/RPS http://www.medicinescomplete.com/about/index.htm
375 British National Formulary for Children (BNF-C) BMJ/RPS http://www.medicinescomplete.com/about/index.htm
5
Suggested texts - to be used for background knowledge as available locally for appropriate elements
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
442 Stockley's Drug Interactions (Via TKN) Medicines Complete http://www.medicinescomplete.com/mc/stockley/current/
301 ABC of Sepsis 2010 if available - comes highly recommended
BMJ Books Wiley Blackwell
Daniels R
378 Infectious Diseases of the Fetus and Newborn (7th Edition) if available
Elsevier Remington J et al
http://www.amazon.co.uk/dp/1416064001/ref=rdr_ext_tmb
479 Medications and Mothers' Milk 2012 if available Hale Publishing Hale T
440 Neonatal Formulary (6th ED) with updates 2011 if available
Wiley Hey E (Editor) http://www.neonatalformulary.com/default.asp
376 Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk 9th ed (via TKN)
Lippincott Williams & Wilkins
Briggs G http://www.knowledge.scot.nhs.uk
302 ABC of HIV and AIDS 6th Ed 2012 if available (comes highly recommended but would need to be purchased)
BMJ Books Wiley Blackwell
Alder MW
346 Oxford Handbook of Tropical Medicine 2005 (New edition published in 2014) if available
Oxford Press Eddleston M et al
http://www.talcuk.org/books/oxford-handbook-of-tropical-medicine-3rd-edition.htm
430 Manson's Tropical Diseases 23rd Ed 2013 if available Elsevier Farrar J et al (Ed)
429 Hunter's Tropical Medicine and Emerging Infectious Disease: Expert Consult -2013 Online and Print, 9e if available
Elsevier Magill AJ et al (ED)
501 Oxford Textbook of Medicine 2003 (via TKN) Oxford University Press
Warrell D Ed http://www.knowledge.scot.nhs.uk/
513 Applied Pharmacokinetics & Pharmacodynamics: Principles of Therapeutic Drug Monitoring 2006
Lippincott Williams & Wilkins
Burton ME et al (Editors)
6
Resources for Element 1 Introduction to Antimicrobial Stewardship CORE RESOURCES
Element 1 - INTRODUCTION TO ANTIMICROBIAL STEWARDSHIP - CORE RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
SAPG & SCOTTISH GOVERNMENT REFERENCES
Scottish Antimicrobial Prescribers Group (SAPG) website Scottish Medicines Consortium
SAPG http://www.scottishmedicines.org.uk/SAPG/Scottish_Antimicrobial_Prescribing_Group__SAPG_
8 Training on Use of Antimicrobials in Clinical Practice (SAPG) (60 mins)(Additional CPD section not compulsory)
NES HIS/SAPG http://www.nes.scot.nhs.uk/education-and-training/by-theme-initiative/healthcare-associated-infections/training-resources/antimicrobials-in-clinical-practice.aspx
107 Good Practice Recommendations for Antimicrobial Use in Frail Elderly Patients in NHS Scotland
SAPG SAPG http://www.scottishmedicines.org.uk/files/sapg/SAPG_Recommendations_for_antibiotic_use_in_frail_elderly_-_February_2013.pdf
121 SAPG Good Practice Recommendations for Hospital Antimicrobial Stewardship in NHS Scotland
SAPG SAPG http://www.scottishmedicines.org.uk/files/sapg/Good_practice_recommendations_for_hospital_antimicrobial_stewardship_2012.pdf
138 Scot MARAP 2008 (Due for update in 2013/14) Scottish Government http://www.scotland.gov.uk/Publications/2008/03/12153030/0
LOCAL HEALTH BOARD REFERENCES
Local health board website or intranet
OTHER ANTIMICROBIAL STEWARDSHIP REFERENCES
140 Guidelines for Developing an Institutional Program to Enhance Antimicrobial Stewardship
Clinical Infectious Diseases 2007; 44:159–77
Dellit TH et al http://www.idsociety.org/Antimicrobial_Agents/#Antimicrobial Stewardship
390 Antimicrobial Stewardship Start Smart then Focus Department of Health
https://www.gov.uk/government/publications/antimicrobial-stewardship-start-smart-then-focus
7
Element 1 - INTRODUCTION TO ANTIMICROBIAL STEWARDSHIP - CORE RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
SCOTTISH PATIENT SAFETY PROGRAMME REFERENCES
489 Scottish Patient Safety Programme Website SPSP Health Improvement Scotland
http://www.scottishpatientsafetyprogramme.scot.nhs.uk/programme
SUPPLEMENTARY RESOURCESElement 1 INTRODUCTION TO ANTIMICROBIAL STEWARDSHIP - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner Presenter
/Author URL link direct to resourceDate Resource Accessed/ Comments
SAPG & SCOTTISH GOVERNMENT REFERENCES
118 SAPG Good Practice Guidance on Ratification of Antimicrobial Policies
SAPG SAPG http://www.scottishmedicines.org.uk/files/GOOD_PRACTICE_GUIDANCE_ON_RATIFICATION_OF_ANTIMICROBIAL_POLICIES.pdf
114 Recommendations for Good Antimicrobial Practice in Acute Hospitals 2005
Scottish Government http://www.scotland.gov.uk/Resource/Doc/69582/0017099.pdf
110 (SAPG): development and impact of the Scottish National Antimicrobial Stewardship Programme (via TKN)
Int J Antimicrob Agents 2011; 38(1): 16-26
Nathwani D et al http://www.sciencedirect.com/science/article/pii/S0924857911001026
113 Antimicrobial stewardship in Scotland: impact of a national programme
Antimicrob Res Inf Cont 2012, 1:7
Nathwani D et al http://www.aricjournal.com/content/1/1/7
OTHER ANTIMICROBIAL STEWARDSHIP REFERENCES
19 Antimicrobials & Infection Management (10 hours to complete full module - can dip in for specific subjects)
NES NI Centre for Pharmacy Learning &
http://www.nes.scot.nhs.uk/education-and-training/by-discipline/pharmacy/about-nes-pharmacy/educational-resources/resources-by-topic/infectious-diseases/
8
Element 1 INTRODUCTION TO ANTIMICROBIAL STEWARDSHIP - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner Presenter
/Author URL link direct to resourceDate Resource Accessed/ Comments
Development antibiotics/antimicrobials-and-infection-management.aspx
109 From intermittent antibiotic point prevalence surveys to quality improvement: experience in Scottish hospitals
Antimicrob Res Inf Cont 2013;2:3
Malcolm W et al http://www.aricjournal.com/content/2/1/3
117 Antimicrobial Stewardship in Australian Hospitals ACSQH Duguid M Cruikshank M
http://www.safetyandquality.gov.au/publications/antimicrobial-stewardship/
230 Annual Report of the Chief Medical Officer 2011: Volume Two
This publication provides a comprehensive overview of the threat of antimicrobial resistance and infectious diseases.
Department of Health
Davies S https://www.gov.uk/government/publications/chief-medical-officer-annual-report-volume-2
231 The missing care bundle: antibiotic prescribing in hospitals (via TKN or Athens login)
Int J Ant Agents 2007; 30:25-29
Cooke FJ et al http://www.ijaaonline.com/article/S0924-8579(07)00146-X/abstract
187 Interventions to improve antibiotic prescribing practices for hospital inpatients (via TKN or Athens login)
CDSR 2013, Issue 4. Art. No.: CD003543.
Davey P et al http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD003543.pub3/abstract
305 Effectiveness of the interventions in antimicrobial stewardship: What works? Updated Cochrane systematic review and systematic review methodology (via TKN) (60 mins)
ASAP Shared Space Davey P http://www.elib.scot.nhs.uk/SharedSpace/pharmacy/Uploads/2013/Jun/20130614155109_Cochrane%20Webinar%20PDavey.pdf
306 Understanding the Determinants of Antimicrobial Prescribing Within Hospitals: The Role of “Prescribing Etiquette”
Clin Infect Dis. (2013) 57 (2): 188-196
Charani E et al http://cid.oxfordjournals.org/content/57/2/188.long
9
Resources for Element 2 Essential microbiology, resistance and basic immune function CORE RESOURCES
Element 2 - ESSENTIAL PHARMACEUTICAL MICROBIOLOGY, BACTERIAL RESISTANCE & BASIC IMMUNE FUNCTION - CORE RESOURCES
Resource ID Name of resource Resource owner Presenter
/Author URL link direct to resourceDate Resource Accessed/ Comments
MICROBIOLOGY & LAB REFERENCES
1 Bugs and Drugs Part 1 (30 mins) NES Kieran Hand http://www.nes.scot.nhs.uk/education-and-training/by-discipline/pharmacy/about-nes-pharmacy/educational-resources/webinars-and-virtual-patient-scenarios/webcasts/bugs-and-drugs-part-1.aspx
15 Basic Microbiology (2 hours) NES NES/LearnPro http://www.nes.scot.nhs.uk/education-and-training/by-theme-initiative/healthcare-associated-infections/online-short-courses/basic-microbiology.aspx
337 A Microbiologists View of Bugs & Drugs for ASAP (50 mins)
NES Alistair Leonard http://www.nes.scot.nhs.uk/education-and-training/by-discipline/pharmacy/about-nes-pharmacy/educational-resources/resources-by-topic/infectious-diseases/antibiotics/a-microbiologists-view-of-bugs-and-drugs-for-asap.aspx
436 An insight into the National Reference Laboratory (47 mins)
NES John Coia http://www.nes.scot.nhs.uk/education-and-training/by-discipline/pharmacy/about-nes-pharmacy/educational-resources/resources-by-topic/infectious-diseases/antibiotics/an-insight-into-the-national-reference-laboratories-for-asap.aspx
BACTERIAL RESISTANCE REFERENCES
12 Bacterial Resistance (2 hours) NES NES/LearnPro http://www.nes.scot.nhs.uk/education-and-training/by-theme-initiative/healthcare-associated-infections/online-short-courses/bacterial-resistance.aspx
Sept 2015 Not available HAI withdrawn
13 Multi-resistant Gram Negative Bacilli (MRGNB) (15 mins)
NES NES/LearnPro http://www.nes.scot.nhs.uk/education-and-training/by-theme-initiative/healthcare-associated-infections/online-
10
Element 2 - ESSENTIAL PHARMACEUTICAL MICROBIOLOGY, BACTERIAL RESISTANCE & BASIC IMMUNE FUNCTION - CORE RESOURCES
Resource ID Name of resource Resource owner Presenter
/Author URL link direct to resourceDate Resource Accessed/ Comments
short-courses/multi-resistant-gram-negative-bacilli-(mrgnb).aspx
138 Scot MARAP 2008 due for update in 2013/14 Scottish Government http://www.scotland.gov.uk/Publications/2008/03/12153030/0
BASIC IMMUNE FUNCTION REFERENCES
386 Clinical Guidelines for Immunoglobulin Use 2nd Ed update March 2012
Department of Health
http://www.nsd.scot.nhs.uk/Documents/clinimmumoMarch12.pdf
101 Your Immune System 101: Introduction to Clinical Immunology (YouTube - skip adverts) (90 mins)
UCSF Dr Katherine Gundling
http://www.youtube.com/watch?v=_oI0jVN4TTI&feature=player_detailpage
102 Basic Immunology - Nuts and Bolts of the Immune System (YouTube - skip adverts) (90 mins)
UCSF Dr Anthony De Franco
http://www.youtube.com/watch?feature=player_detailpage&v=mFNxXfwlP3A
SUPPLEMENTARY RESOURCESElement 2 - ESSENTIAL PHARMACEUTICAL MICROBIOLOGY, BACTERIAL RESISTANCE & BASIC IMMUNE FUNCTION - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner Presenter
/Author URL link direct to resourceDate Resource Accessed/ Comments
MICROBIOLOGY & LAB REFERENCES
466 BSAC Methods for Antimicrobial Susceptibility Testing Version 12 May 2013
BSAC BSAC http://bsacstage.pharma-mix.com////wp-content/uploads/2012/02/Version-12-Apr-2013_final.pdf
207 Guidelines on the laboratory diagnosis and susceptibility testing of MRSA
J Antimicrob Chemother 2005; 56: 1000 - 1018
Brown DFJ et al http://jac.oxfordjournals.org/content/56/6/1000.full.pdf
221 Guidance on the diagnosis and management of PVL-associated Staphylococcus aureas infection 2008
HPA/DoH HPA/DoH http://www.hpa.org.uk/webc/HPAwebFile/HPAweb_C/1218699411960
52 BSAC antimicrobial susceptibility testing – from Stokes BSAC Dr Derek Brown http://bsac.org.uk/events/past-events-2011/spring-
11
Element 2 - ESSENTIAL PHARMACEUTICAL MICROBIOLOGY, BACTERIAL RESISTANCE & BASIC IMMUNE FUNCTION - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner Presenter
/Author URL link direct to resourceDate Resource Accessed/ Comments
to European harmonization to world? (20 mins) meeting-agm-2011/spring-meeting-2011/
BACTERIAL RESISTANCE REFERENCES
276 Rapid evolution and spread of carbapenemases among Enterobacteriaceae in Europe (TKN or Athens login)
Eur Clin Microbiol Infect 2012;18: 413–431
Canton R et al http://onlinelibrary.wiley.com/doi/10.1111/j.1469-0691.2012.03821.x/abstract
278 Has the era of untreatable infections arrived? J Antimicrob Chemother 2009;64 Suppl1:i29-i36
Livermore DM http://jac.oxfordjournals.org/content/64/suppl_1/i29.full.pdf+html
7 Patterns of Antimicrobial Use and Resistance in Scotland(MSc) (56 mins)
NES William Malcolm http://www.video3uk.com/login.aspx
20 Avoiding Antibiotic Resistance: the role of the pharmacy team (NB quite old resource, may soon be replaced) (6 hours to complete whole module - can dip in for specific subjects)
NES NES Portal http://www.nes.scot.nhs.uk/education-and-training/by-discipline/pharmacy/about-nes-pharmacy/educational-resources/resources-by-topic/infectious-diseases/antibiotics/avoiding-antibiotic-resistancethe-role-of-the-pharmacy-team.aspx
44 What is happening now? Epidemiology of resistance (20 mins)
BSAC Prof Neil Woodford
http://bsac.org.uk/events/past-events-2013/bsac-spring-meeting-2013/bsac-spring-meeting-agm-2013-videos/
45 Carbapenemases in Practice (29 mins) BSAC Dr Andrew Dodgson
http://bsac.org.uk/events/past-events-2013/bsac-spring-meeting-2013/bsac-spring-meeting-agm-2013-videos/
46 Neisseria gonorrhea – the first untreatable infection (20 mins)
BSAC Prof Catherine Ison
http://bsac.org.uk/events/past-events-2013/bsac-spring-meeting-2013/bsac-spring-meeting-agm-2013-videos/
48 VRE – one difficult Gram positive after another. Treatment options for severe infections (26 mins)
BSAC Dr Nick Brown http://bsac.org.uk/events/past-events-2013/bsac-spring-meeting-2013/bsac-spring-meeting-agm-2013-videos/
49 Optimisation of combination therapy for treatment of Pseudomonas aeruginosa (10 mins)
BSAC Dr Alexander Cochrane
http://bsac.org.uk/events/past-events-2013/bsac-spring-meeting-2013/bsac-spring-meeting-agm-2013-videos/
51 New Uses for Old Agents (25 mins) BSAC Dr Kieran Hand http://bsac.org.uk/events/past-events-2013/bsac-spring-meeting-2013/bsac-spring-meeting-agm-2013-videos/
12
Element 2 - ESSENTIAL PHARMACEUTICAL MICROBIOLOGY, BACTERIAL RESISTANCE & BASIC IMMUNE FUNCTION - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner Presenter
/Author URL link direct to resourceDate Resource Accessed/ Comments
60 Antibiotic cycling - a worthwhile weapon against gram negative resistance? (30 mins)
BSAC Bob Masterton http://www.online-web-presentations.com/BSAC_2010/
111 Overview of strategies for overcoming the challenge of antimicrobial resistance
Expert Rev. Clin. Pharmacol. 3(5), 667–686 (2010)
Davey P et al http://www.scottishmedicines.org.uk/files/sapg/Davey_2010.pdf
209 Effective antibacterials: at what cost? The economics of antibacterial resistance and its control
J. Antimicrob. Chemother.2012; 66: 1948-1953
WhiteAR http://jac.oxfordjournals.org/content/66/9/1948.full.pdf
212 Risks of extended-spectrum beta-lactamases (via TKN/Athens login)
DTB 2008;46:21-24 http://dtb.bmj.com/content/46/3/21.full
222 The evolving threat of antimicrobial resistance WHO http://whqlibdoc.who.int/publications/2012/9789241503181_eng.pdf
223 The Future of antibiotics resistance n engl j med 368;4 nejm.org january 24, 2013
Spellberg B et al http://www.nejm.org/doi/pdf/10.1056/NEJMp1215093
271 Antibiotic Prescribing - Reduce and Resist (via TKN) ASAP Shared Space Philip C http://www.elib.scot.nhs.uk/SharedSpace/pharmacy/Uploads/2010/Sep/20100922142033_quiz%20section%20Reduce%20and%20resist%20section%202010.pdf
275 Susceptibility of Klebsiella pneumoniae Isolates from Intra-Abdominal Infections and Molecular Characterization of Ertapenem-Resistant Isolates
Antimicrob Agents Chemother. 2011 55(8): 3917–3921
Hawser SP et al http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3147618/
BASIC IMMUNE FUNCTION REFERENCES
379 Immunisation against infectious disease: the Green Book
Department of Health
https://www.gov.uk/government/organisations/public-health-england/series/immunisation-against-infectious-disease-the-green-book
384 Infection and Immunity 3rd Ed 2008 or 4th Ed 2013 if available
Oxford University Press
Playfair J Bancroft G
13
Element 2 - ESSENTIAL PHARMACEUTICAL MICROBIOLOGY, BACTERIAL RESISTANCE & BASIC IMMUNE FUNCTION - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner Presenter
/Author URL link direct to resourceDate Resource Accessed/ Comments
385 Basic & Clinical Immunology if available Churchill Livingstone Peakman M Vergani D
14
Resources for Element 3 Antimicrobial agents by therapeutic class CORE RESOURCES
Element 3 - ANTIBIOTICS BY THERAPEUTIC CLASS - CORE RESOURCES
Resource ID Name of resource Resource ownerPresenter/Author URL link direct to resource
Date Resource Accessed/ Comments
GENERAL CLASSIFICATION OF ANTIBIOTICS REFERENCES AND LOCAL GUIDELINES
Local Antimicrobial Prescribing Guidelines
2 Bugs and Drugs Part 2 (35 mins) NES Kieran Hand http://www.nes.scot.nhs.uk/education-and-training/by-discipline/pharmacy/about-nes-pharmacy/educational-resources/webinars-and-virtual-patient-scenarios/webcasts/bugs-and-drugs-part-2.aspx
443 Electronic Medicines Compendium eMC Datapharm http://www.medicines.org.uk/emc/
219 Sanford Guide 2013 if access available (subscription or purchase required)
Antimicrobial Therapy Inc
Gilbert et al (Eds)
http://www.sanfordguide.com/
374 British National Formulary (BNF) BMJ/RPS http://www.medicinescomplete.com/about/index.htm
ADVERSE DRUG REACTIONS & INTERACTIONS REFERENCES
442 Stockley's Drug Interactions (via TKN) Medicines Complete http://www.medicinescomplete.com/mc/stockley/current/
467 Yellow Card Reporting Website MHRA MHRA http://yellowcard.mhra.gov.uk/
15
SUPPLEMENTARY RESOURCESElement 3 - ANTIBIOTICS BY THERAPEUTIC CLASS - SUPPLEMENTARY RESOURCESResource ID Name of resource Resource owner Presenter
/Author URL link direct to resourceDate Resource Accessed/ Comments
GENERAL CLASSIFICATION OF ANTIBIOTICS REFERENCES AND LOCAL GUIDELINES
19 Antimicrobials & Infection Management (10 hours to complete full module - can dip in for specific subjects)
NES NI Centre for Pharmacy Learning & Development
http://www.nes.scot.nhs.uk/education-and-training/by-discipline/pharmacy/about-nes-pharmacy/educational-resources/resources-by-topic/infectious-diseases/antibiotics/antimicrobials-and-infection-management.aspx
125 Management of infection guidance for primary care HPA
HPA http://www.hpa.org.uk/webc/HPAwebFile/HPAweb_C/1279888711402
215 Gentamicin ototoxicity: a 23 year selected case series of 103 patients
MJA June 2012 ;196(11) 701-05
Ahmed RM et al https://www.mja.com.au/journal/2012/196/11/gentamicin-ototoxicity-23-year-selected-case-series-103-patients
217 2005-2006 Field Guide to Antibiotic Therapy Drug Topics Astra Zeneca
http://www.zubnistranky.cz/atb.pdf
218 Carbapenem Antibiotics for serious infections (via TKN or Athens login)
BMJ 2012;344:e3236 Hawkey PM et al http://www.bmj.com/content/344/bmj.e3236
220 Johns Hopkins ABX Guide (subscription required - some MI centres may subscribe)
Unbound Medicine Inc
http://www.hopkinsguides.com/hopkins/ub/index/Johns_Hopkins_ABX_Guide/All_Topics/A
441 UKCPA Drug Dosing in Extremes of Body Weight in Critically Ill Patients 2013
UKCPA http://www.nes.scot.nhs.uk/media/2536057/vt3_drug_dosing_ukcpa_doc__for_resources__website__jan_2014.pdf
16
Resources for Element 4 Healthcare Acquired Infection (HAI)CORE RESOURCES
Element 4 - HEALTHCARE ASSOCIATED INFECTION (HAI) - CORE RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
HAI GENERAL REFERENCES
387 HPS Compendium of Healthcare Associated Infection Guidance
Health Protection Scotland
http://www.hps.scot.nhs.uk/haiic/publicationsdetail.aspx?id=47911
CDI REFERENCES
3 Bugs and Drugs Part 3 Clostridium difficile associated disease (CDAD) (15 mins)
NES Kieran Hand http://www.nes.scot.nhs.uk/education-and-training/by-discipline/pharmacy/about-nes-pharmacy/educational-resources/webinars-and-virtual-patient-scenarios/webcasts/bugs-and-drugs-c-difficile.aspx
10 Clostridium difficile HIA Learning Tutorial (2 hours) NES NES/LearnPro http://www.nes.scot.nhs.uk/education-and-training/by-theme-initiative/healthcare-associated-infections/online-short-courses/c-difficile-a-clinical-tutorial.aspx
11 Clostridium difficile HAI Clinical Scenario (60 mins) NES NES/LearnPro http://www.nes.scot.nhs.uk/education-and-training/by-theme-initiative/healthcare-associated-infections/online-short-courses.aspx
327 C Difficile Associated Disease Clinical Vignette (20) (free registration for HCPs) (2 hours)
PAUSE BSAC http://www.pause-online.org.uk
437 Guidance on Prevention and Control of Clostridium difficile Infection (CDI) in Healthcare Settings in Scotland
HPS HPS http://www.documents.hps.scot.nhs.uk/about-hps/hpn/clostridium-difficile-infection-guidelines.pdf
388 SMC Advice on fidaxomicin Scottish Medicines Consortium
https://www.scottishmedicines.org.uk/SMC_Advice/Advice/791_12_fidaxomicin_dificlir/fidaxomicin_Dificlir
SABs / MRSA REFERENCES
283 Clinical Practice Guidelines for the Diagnosis and Management of Intravascular Catheter-Related
Clinical Infectious Diseases
Mermel LA et al http://cid.oxfordjournals.org/content/49/1/1.full
17
Element 4 - HEALTHCARE ASSOCIATED INFECTION (HAI) - CORE RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
Infection: 2009 Update by the Infectious Diseases Society of America (note corrigendum)
2009;49(1):1-45
319 MRSA Treatment Errors Clinical Vignette (12) (free registration for HCPs) (60 mins)
PAUSE BSAC http://www.pause-online.org.uk
325 IV Catheter Related Infection Clinical Vignette (18) (free registration for HCPs) (2 hours)
PAUSE BSAC http://www.pause-online.org.uk
17 MRSA An Online Tutorial (3 hours) NES NES/LearnPro http://www.nes.scot.nhs.uk/education-and-training/by-theme-initiative/healthcare-associated-infections/online-short-courses/mrsa-a-clinical-tutorial.aspx
18 MRSA Clinical Scenario (2 hours) NES NES/LearnPro http://www.nes.scot.nhs.uk/education-and-training/by-theme-initiative/healthcare-associated-infections/online-short-courses/mrsa-a-clinical-scenario.aspx
22 Preventing Catheter Related Bloodstream Infections (60 mins)
NES NES/LearnPro http://www.nes.scot.nhs.uk/education-and-training/by-theme-initiative/healthcare-associated-infections/online-short-courses/preventing-catheter-related-bloodstream-infections.aspx
391 Staphyloccus Aureus Bacteraemia Algorithm and Quality Indicators 2012/13
SAPG SAPG http://www.scottishmedicines.org.uk/SAPG/Quality_Improvement/Staph_aureus_bacteraemia
203 Guidelines (2008) for the prophylaxis and treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections in the United Kingdom
J. Antimicrob. Chemother., May 2009; 63: 849 - 861
Gould FK et al http://jac.oxfordjournals.org/content/63/5/849.full.pdf
18
SUPPLEMENTARY RESOURCESElement 4 - HEALTHCARE ASSOCIATED INFECTION (HAI) - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
HAI GENERAL REFERENCES
6 Healthcare Associated Infection (MSc)(free registration required) (45 mins)
NES Jacqueline Sneddon
http://www.nes.scot.nhs.uk/education-and-training/by-discipline/pharmacy/about-nes-pharmacy/educational-resources/webinars-and-virtual-patient-scenarios/webinars.aspx
389 Scottish Government HAI Task Force Scottish Government http://www.scotland.gov.uk/Topics/Health/Services/Preventing-Healthcare-Infections/Infection-Monitoring/Taskforce
CDI REFERENCES
150 Clinical Practice Guidelines for Clostridium difficile Infection in Adults: 2010
Infect Cont Hoso Epidem 2010 ; 31 : 431 -455
Cohen SH et al http://www.idsociety.org/Organism/
186 Successful use of feedback to improve antibiotic prescribing and reduce Clostridium difficile infection: a controlled interrupted time series
JAC (2007) 59 (5): 990-995.
Fowler S et al http://jac.oxfordjournals.org/content/59/5/990.full
439 Updated guidance on the management and treatment of Clostridium difficile infection (English Guidance)
HPA HPA www.hpa.org.uk/webc/HPAwebfile/HPAweb_C/1317138914904
SABs MRSA REFERENCES
166 Management of Patients with Infections Caused by Methicillin-Resistant Staphylococcus Aureus
Clinical Infectious Diseases ; 2011 ; 52 : 1 -38
LIU C et al http://www.idsociety.org/Organism/
205 Guidelines for UK practice for the diagnosis and management of (MRSA) infections presenting in the community
J. Antimicrob. Chemother.,2008; 61: 976 - 994.
Nathwani D et al http://jac.oxfordjournals.org/content/61/5/976.full.pdf
19
Element 4 - HEALTHCARE ASSOCIATED INFECTION (HAI) - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
392 Clinical Management of SAB (via TKN / Athens login) Lancet Inf Dis 2011;11:208-22
Thwaites GE et al
http://www.thelancet.com/journals/laninf/article/PIIS1473-3099(10)70285-1/abstract
368 MRSA Screening and Suppression - Quick Reference Guide for Primary Care
HPA http://www.hpa.org.uk/Topics/InfectiousDiseases/InfectionsAZ/PrimaryCareGuidance/
20
Resources for Element 5 Sepsis Diagnosis and Management CORE RESOURCES
Element 5 - SEPSIS - CORE RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
GENERAL SEPSIS REFERENCES
84 Neutropenic Sepsis CG151 2012 NICE NICE http://publications.nice.org.uk/neutropenic-sepsis-prevention-and-management-of-neutropenic-sepsis-in-cancer-patients-cg151
272 Sepsis - Improving care, improving outcome (via TKN) (30 mins)
ASAP Shared Space Rooney K http://www.elib.scot.nhs.uk/SharedSpace/pharmacy/Uploads/2012/Mar/20120307120621_ASAP%20presentation%20Kevin%20Rooney.pdf
334 Diagnosis and Treatment of Sepsis for ASAP (45 mins) NES Dilip Nathwani http://www.nes.scot.nhs.uk/education-and-training/by-discipline/pharmacy/about-nes-pharmacy/educational-resources/resources-by-topic/infectious-diseases/infection/diagnosis-and-treatment-of-sepsis-for-asap.aspx
381 NHS Scotland NEWS & Sepsis Screening Tool iTunes NES https://itunes.apple.com/gb/app/nhs-scotland-news-sepsis-screening/id657497806?mt=8
435 Antibiotic Use within Intensive Care (34 mins) NES Radha Sundaram http://www.nes.scot.nhs.uk/education-and-training/by-discipline/pharmacy/about-nes-pharmacy/educational-resources/resources-by-topic/infectious-diseases/antibiotics/antibiotic-use-within-intensive-care-for-asap.aspx
SEPSIS-INDUCED ORGAN DYSFUNCTION REFERENCES
279 Mechanisms of Sepsis -Induced Organ Dysfunction (via TKN / Athens login)
Critical Care Medicine 2007;35(10):2408-16
Abraham E et al http://www.knowledge.scot.nhs.uk/home/search-results.aspx?q=publicid%3a%22ebscocinahl%7c2009738199%22&pm=fql&expand=true&portal=
21
SUPPLEMENTARY RESOURCESElement 5 - SEPSIS - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
GENERAL SEPSIS REFERENCES
149 2012 International Guidelines for Management of Severe Sepsis and Septic Shock
Critical Care Medicine ; 2013 ; 41 : 580 -637
Dellinger PR http://www.idsociety.org/Organ_System/
213 The sepsis six and the severe sepsis resuscitation bundle: a prospective observational cohort study (via TKN / Athens login)
Emerg Med J 2011;28:6 507-512
Daniels R et al http://emj.bmj.com/search?submit=yes&pubdate_year=&volume=&firstpage=&doi=&author1=Daniels+R&author2=Nutbeam+T&title=sepsis&andorexacttitle=and&titleabstract=&andorexacttitleabs=and&fulltext=&andorexactfulltext=and&resourcetype=HWCIT&fmonth=&fyear=2010&tm
301 ABC of Sepsis 2010 if available BMJ Books wiley Blackwell
Daniels R
309 Septic Shock Clinical Vignette (02) (free registration for HCPs) (2 hours)
PAUSE BSAC http://www.pause-online.org.uk
380 Severe sepsis and septic shock NEJM Derek C et al http://www.nejm.org/doi/full/10.1056/NEJMra1208623
382 Critical Care & Trauma Part 8: Surgical Sepsis Office of International Surgery, U. Toronto
Jackson A et al http://ptolemy.library.utoronto.ca/content/critical-care-and-trauma-part-8-surgical-sepsis
SEPSIS BIOMARKERS REFERENCES
280 Molecular diagnostics of sepsis where are we today? (via TKN / Athens login)
Int J Med Microbiol 2010;300(6):411-3
Bauer M et al http://www.sciencedirect.com/science/article/pii/S1438422110000317
281 Use of procalcitonin to reduce patients' exposure to antibiotics in intensive care units (PRORATA trial):(via TKN / Athens login)
Lancet 2010;375(9713):463-74
Bouadma L et al http://www.sciencedirect.com/science/article/pii/S0140673609618791
370 Procalcitonin - what does it mean for sepsis (YouTube) BC Patient Safety & Reynolds S http://www.youtube.com/watch?v=ie0QpnRCfbs
22
Element 5 - SEPSIS - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
(46 mins) Quality Council
371 Novel biomarkers for infection & sepsis 2010 (30 mins) BSAC Dark P http://bsac.org.uk/PlayVideoPage.html?url=https://s3-eu-west-1.amazonaws.com/havap-2010/08_Paul_Dark
23
Resources for element 6 Acute respiratory tract infection incorporating pneumonia and COPD CORE RESOURCES
Element 6 - ACUTE RRESPIRATORY TRACT INFECTION - CORE RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
GENERAL RESPIRATORY REFERENCES
9 Antibiotic Prescribing for Today's Practitioner (2 hours) NES NES/LearnPro http://www.nes.scot.nhs.uk/education-and-training/by-theme-initiative/healthcare-associated-infections/online-short-courses/antibiotic-prescribing.aspx
PNEUMONIA & INFLUENZA REFERENCES
90 Pneumonia CG DRAFT NICE NICE http://guidance.nice.org.uk/index.jsp?action=find
122 Community Acquired Pneumonia Care Bundle SAPG http://www.scottishmedicines.org.uk/files/sapg/Community_Acquired_Pneumonia_Care_Bundle-DRAFTv0.pdf
193 BTS Guideline on Management of Community Acquired Pneumonia in Adults (2009)
Thorax 2009;64(3) Lim WS et al http://www.brit-thoracic.org.uk/guidelines-and-quality-standards/community-acquired-pneumonia-in-adults-guideline/
204 Guidelines for the management of hospital-acquired pneumonia in the UK: Report of the Working Party of BSAC
J. Antimicrob. Chemother., July 2008; 62: 5 - 34
Masterton RG http://jac.oxfordjournals.org/content/62/1/5.full.pdf+html?sid=490c8455-ddc9-4139-8069-a5ded90e4e7b
409 HPA guidance on use of antiviral agents for the treatment and prophylaxis of influenza (Oct 2012)
HPA http://www.hpa.org.uk/webc/HPAwebFile/HPAweb_C/1317131466016
OTHER ACUTE LRTI REFERENCES
201 Chronic obstructive pulmonary disease NICE CG101 NICE http://guidance.nice.org.uk/CG101
262 GOLD Initiative for Chronic Obstructive Lung Disease 2013
GOLD http://www.goldcopd.org/guidelines-resources.html
265 Atypical Infection? Respiratory Case Study (via TKN) ASAP Shared Space Sneddon J http://www.elib.scot.nhs.uk/SharedSpace/pharmacy/Uploads/2013/Mar/20130326101614_Atypical%20Case%20Study%20Resp.pdf
24
Element 6 - ACUTE RRESPIRATORY TRACT INFECTION - CORE RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
UPPER RESPIRATORY TRACT INFECTION REFERENCES
88 Respiratory Tract Infections in primary care CG69 NICE NICE http://publications.nice.org.uk/respiratory-tract-infections-antibiotic-prescribing-cg69
SUPPLEMENTARY RESOURCESElement 6 - ACUTE RESPIRATORY TRACT INFECTION - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource ownerPresenter/Author URL link direct to resource
Date Resource Accessed/ Comments
PNEUMONIA & INFLUENZA REFERENCES
14 Preventing Ventillator Associated Pneumonia (60 mins)
NES LearnPro http://www.nes.scot.nhs.uk/education-and-training/by-theme-initiative/healthcare-associated-infections/online-short-courses/preventing-ventilator-associated-pneumonia.aspx
183 Seasonal Influenza in Adults and Children—Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management: Clinical Practice Guidelines
Clin Infect Dis 2009 ; 48 : 1003 -1032
Harper SA http://www.idsociety.org/Organism/
195 British Thoracic Society guidelines for the management of community acquired pneumonia in children: update 2011
Thorax 2011;66 (2) Harris M et al http://www.brit-thoracic.org.uk/guidelines-and-quality-standards/community-acquired-pneumonia-in-children-guideline/
200 Guidelines for the clinical management of patients with an influenza-like illness during an influenza pandemic
Thorax 2007;62;1-46 Lim WS http://www.brit-thoracic.org.uk/guidelines-and-quality-standards/influenza/
224 Ventilator associated pneumonia (via TKN / Athens login)
BMJ 2012;334e3325 Hunter JD http://www.bmj.com/content/344/bmj.e3325
25
Element 6 - ACUTE RESPIRATORY TRACT INFECTION - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource ownerPresenter/Author URL link direct to resource
Date Resource Accessed/ Comments
308 Pneumonia Clinical Vignette (01) (free registration for HCPs) (2 hours)
PAUSE BSAC http://www.pause-online.org.uk
482 Analysis Relationships Between Pharmacokinetic Parameters in silico/in vivo of Selected Antiviral Drugs Based on Structural Analysis
Adv Clin Exp Med 2008, 17, 3, 285–292
Grabowski T et al
http://www.advances.am.wroc.pl/pdf/2008/17/3/285.pdf
URTI REFERENCES
38 Management of Sore Throat and Indication for Tonsillectomy (2010) SIGN 117
SIGN SIGN http://www.sign.ac.uk/guidelines/fulltext/117/index.html
160 IDSA Clinical Practice Guideline for Acute Bacterial Rhinosinusitis in Children and Adults"US Update on NICE CG 69
Clinical Infectious Diseases ; 2012 ; : e1 -e41
Chow AW et al http://www.idsociety.org/Organ_System/#Lower/Upper Respiratory
161 Clinical Practice Guideline for the Diagnosis and Management of Group A Streptococcal Pharyngitis: 2012 ( more recent than SIGN 117)
Clinical Infectious Diseases ; 2012 ; : 1 -17
Shulman ST http://www.idsociety.org/Organ_System/#Lower/Upper Respiratory
263 Antibiotics for sore throat (via TKN / Athens login) CDSR 2006(4) Art No CD000023
Spinks A http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD000023.pub3/abstract;jsessionid=2E5B87CAD4DC6091A291B972C7D4889F.d01t04
322 Sore Throat Clinical Vignette (15) (free registration for HCPs) (90 mins)
PAUSE BSAC http://www.pause-online.org.uk
26
Resources for element 7 - Urinary tract infection (UTI)CORE RESOURCES
Element 7 - URINARY TRACT INFECTION (UTI) - CORE RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
GENERAL UTI REFERENCES
Local Antimicrobial Guidelines
9 Antibiotic Prescribing for Today's Practitioner(cases 3 & 7)
NES NES/LearnPro http://www.nes.scot.nhs.uk/education-and-training/by-theme-initiative/healthcare-associated-infections/online-short-courses/antibiotic-prescribing.aspx
43 Management of Suspected Bacterial Urinary Tract Infections in Adults (updated 2012) SIGN 88
SIGN http://www.sign.ac.uk/guidelines/fulltext/88/index.html
74 Urinary Tract Infection in Children CG54 NICE NICE http://publications.nice.org.uk/urinary-tract-infection-in-children-cg54
108 Decisions Aid for Diagnosis and Management of Suspected UTI in Older People
SAPG SAPG http://www.scottishmedicines.org.uk/files/sapg/SAPG_Decision_aid_for_UTI_in_older_people_-_May_2013.pdf
253 European Association of Urology Guidelines on Urological Infections 2013 (Use in conjunction with local antibiotic prescribing guidelines)
EAU Grabe M et al http://www.uroweb.org/gls/pdf/18_Urological%20infections_LR.pdf
PYELONEPHRITIS REFERENCES
156 Guidelines for Antimicrobial Treatment of Acute Uncomplicated Cystitis and Pyelonephritis in Women (refer to local prescribing guidelines)
Clin Infect Dis 2011 ; 52 : e103 -e120
Gupta K et al http://www.idsociety.org/Organ_System/#Genitourinary
299 Reese & Betts' practical approach to infectious diseases 5th Ed 2003 (on TKN) or alternative available text book for background information (UTI/pyelonephritis Chapter used in conjunction with local guidelines for specific antibiotics)
Lippincott Williams and Wilkins
Betts RF et al http://www.knowledge.scot.nhs.uk/home/library/books/books-
27
Element 7 - URINARY TRACT INFECTION (UTI) - CORE RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
CAUTI REFERENCES
155 Diagnosis, Prevention, and Treatment of Catheter-Associated Urinary Tract Infection in Adults: 2009
Clin Infect Dis 2010 ; 50 : 625 -663
Hooton TM http://www.idsociety.org/Organ_System/#Genitourinary
SUPPLEMENTARY RESOURCESElement 7 - URINARY TRACT INFECTION - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
GENERAL UTI REFERENCES
154 Guidelines for the Diagnosis and Treatment of Asymptomatic Bacteriuria in Adults
Clin Infect Dis 2005 ; 40 : 643 -654
Nicolle LE http://www.idsociety.org/Organ_System/#Genitourinary
225 Presentation, pattern, and natural course of severe symptoms, and role of antibiotics and antibiotic resistance among patients presenting with suspected uncomplicated urinary tract infection in primary care: observational study. (via TKN / Athens login)
BMJ 2010;340:b5633 Little P et al http://www.bmj.com/content/340/bmj.b5633?view=long&pmid=20139213
313 UTI in Pregnancy Clinical Vignette(06) NB refer to local policy for choice of antibiotic regimens (free registration for HCPs) (90 mins)
PAUSE BSAC http://www.pause-online.org.uk
PYELONEPHRITIS REFERENCES
312 UTI Pyelonephritis Clinical Vignette(05) NB drug regimens differ from latest guidance (free registration for HCPs) (2 hours)
PAUSE BSAC http://www.pause-online.org.uk
315 Pyelonephritis Clinical Vignette (08) NB drug regimens differ from latest guidance (free
PAUSE BSAC http://www.pause-online.org.uk
28
Element 7 - URINARY TRACT INFECTION - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
registration for HCPs) (2 hours)
CAUTI REFERENCES
316 Catheter Associated Infection Clinical Vignette(09 ) (free registration for HCPs) (90 mins)
PAUSE BSAC http://www.pause-online.org.uk
29
Resources for Element 8 Skin and soft tissue infection (SSTI) CORE RESOURCES
Element 8 - SKIN AND SOFT TISSUE INFECTION (SSTI) - CORE RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
GENERAL SSTI REFERENCES
165 Practice Guidelines for the Diagnosis and Management of Skin and Soft Tissue Infections
Clin Infect Dis 2005 ; 41 : 1373 -1406
Stevens DL et al http://www.idsociety.org/Organ_System/#Skin & Soft Tissue
434 Treating infections in Skin & Soft Tissue in acute and OPAT settings (60 mins) Video and handouts
NES Andrew Seaton http://vimeo.com/79984822 for video
and
http://www.nes.scot.nhs.uk/education-and-training/by-discipline/pharmacy/about-nes-pharmacy/educational-resources/resources-by-topic/infectious-diseases/antibiotics/treating-infection-in-skin,-soft-tissue,-bone-and-joints-for-asap.aspxfor handout
CELLULITIS & VENOUS LEG ULCER REFERENCES
216 Diagnosis and management of cellulitis (via TKN / Athens login)
BMJ 2012; 345:e4955 Phoenix G http://www.bmj.com/content/345/bmj.e4955
310 Cellulitis Clinical Vignette (03) (free registration for HCPs) (90 mins)
PAUSE BSAC http://www.pause-online.org.uk
369 Venous Leg Ulcers: Infection Diagnosis & Microbiology Investigation
HPA http://www.hpa.org.uk/Topics/InfectiousDiseases/InfectionsAZ/PrimaryCareGuidance/
NECROTISING FASCIITIS AND OTHER SERIOUS SSTI REFERENCES
227 Necrotising Fasciitis (via TKN / Athens login) BMJ 2005;330:830 Hasham S et al http://www.bmj.com/content/330/7495/830
30
Element 8 - SKIN AND SOFT TISSUE INFECTION (SSTI) - CORE RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
256 Lyme Borreliosis (via TKN / Athens login) Lancet 379 Feb 2012(9814);461-76
Stanek G et al http://www.sciencedirect.com/science/article/pii/S0140673611601037
DIABETIC FOOT ULCER REFERENCES
116 Use of antibiotics in people with diabetic foot disease - a consensus statement
The Diabetic Foot Journal Vol 12 No 2 2009
Leese G et al http://www.scottishmedicines.org.uk/files/sapg/Use_of_Antibiotics_in_people_with_diabetic_foot_disease_-_Consensus_Statement_-_2009.pdf
320 Foot Infection in Diabetic Ulcer Clinical Vignette (13) (free registration for HCPs) (90 mins)
PAUSE BSAC http://www.pause-online.org.uk
MRSA & PVL-SA REFERENCES
282 Guidance on the diagnosis and management of PVL-associated staphylococcus aureus infections (PLL-SA) in England (Awaiting Scottish Document in 2014)
HPA Public Health England
http://www.hpa.org.uk/Publications/InfectiousDiseases/InfectionControl/0811GuidanceonthediagnosisandmanagementofPVLSA/
203 Guidelines (2008) for the prophylaxis and treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections in the United Kingdom
J. Antimicrob. Chemother., May 2009; 63: 849 - 861
Gould FK et al http://jac.oxfordjournals.org/content/63/5/849.full.pdf
SUPPLEMENTARY RESOURCESElement 8 - SKIN AND SOFT TISSUE INFECTION (SSTI) - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
GENERAL SSTI REFERENCES
228 Skin and soft tissue infection diagnosis and management (Registration required with RPS - fee)
Clinical Pharmacist 2009;1:13-22
Seaton RA http://www.pjonline.com/search/all?filter0=skin+and+soft+tissue+infection+diagnosis+and+ma
31
Element 8 - SKIN AND SOFT TISSUE INFECTION (SSTI) - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
nagement&filter8=&filter7%5BClinical+Pharmacist%5D=Clinical+Pharmacist&filter4=2009&filter5=&filter6=&filter2=**ALL**&filter1=**ALL**&x=12&y=11
CELLULITIS & VENOUS LEG ULCER REFERENCES
226 Antibiotics and antiseptics for venous leg ulcers (via TKN / Athens login)
Cochrane Database Syst Rev. 2014, Issue 1. Art. No.: CD003557.
O'Meara S et al http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD003557.pub5/abstract
NECROTISING FASCIITIS AND OTHER SERIOUS SSTI REFERENCES
167 The Clinical Assessment, Treatment, and Prevention of Lyme Disease, Human Granulocytic Anaplasmosis, and Babesiosis
Clin Infect Dis 2006 ; 43 : 1089 -1134
Wormser GP et al
http://www.idsociety.org/Organism/
DIABETIC FOOT ULCER REFERENCES
92 Diabetic Foot Problems CG119 NICE NICE http://publications.nice.org.uk/diabetic-foot-problems-cg119
164 Diagnosis and Treatment of Diabetic Foot Infections Clin Infect Dis 2012 ; 54 : e132 -e173
Lipsky BA http://www.idsociety.org/Organ_System/#Skin & Soft Tissue
MRSA & PVL-SA REFERENCES
166 Management of Patients with Infections Caused by Methicillin-Resistant Staphylococcus Aureus
Clinical Infectious Diseases ; 2011 ; 52 : 1 -38
LIU C et al http://www.idsociety.org/Organ_System/#Skin & Soft Tissue
205 Guidelines for UK practice for the diagnosis and management of (MRSA) infections presenting in the community
J. Antimicrob. Chemother.,2008; 61: 976 - 994.
Nathwani D et al http://jac.oxfordjournals.org/content/61/5/976.full.pdf
229 Skin and soft tissue infection focus on MRSA Clinical Pharmacist Seaton RA http://www.pjonline.com/search/all?
32
Element 8 - SKIN AND SOFT TISSUE INFECTION (SSTI) - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
(Registration required with RPS - fee) 2009;1:23-28 filter0=skin+and+soft+tissue+infection+diagnosis+and+management&filter8=&filter7%5BClinical+Pharmacist%5D=Clinical+Pharmacist&filter4=2009&filter5=&filter6=&filter2=**ALL**&filter1=**ALL**&x=12&y=11
OTHER SSTI REFERENCES
364 Acne Vulgaris (30 mins) NICE CKS http://cks.nice.org.uk/acne-vulgaris
366 Atopic eczema in children: Management of atopic eczema in children from birth up to the age of 12 years
NICE http://publications.nice.org.uk/atopic-eczema-in-children-cg57
367 Fungal Skin and Nail Infections Primary Care Quick Reference Guide
HPA http://www.hpa.org.uk/webc/HPAwebFile/HPAweb_C/1240294785726
431 NICE CKS Guidelines on Fungal nail & skin infections NICE NICE http://cks.nice.org.uk/
33
Resources for Element 9 Surgical infection & prophylaxisCORE RESOURCES
Element 9 - SURGICAL INFECTION AND PROPHYLAXIS -CORE RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
GENERAL SURGICAL INFECTION & PROPHYLAXIS REFERENCES (also covering MRSA)
41 Antibiotic Prophylaxis in Surgery (2008) SIGN 104 SIGN http://www.sign.ac.uk/guidelines/fulltext/104/index.html
87 Surgical Site Infection CG74 NICE NICE http://publications.nice.org.uk/surgical-site-infection-cg74
119 SAPG Good Practice Recommendations for Surgical and Procedural Antibiotic Prophylaxis 2012
SAPG SAPG http://www.scottishmedicines.org.uk/files/sapg/Good_practice_recommendations_for_surgical_prophylaxis_2012.pdf
139 Clinical practice guidelines for antimicrobial prophylaxis in surgery
Am J Health Syst Pharm 2013; 70: 195-283
Bratzler DW et al http://www.idsociety.org/Antimicrobial_Agents/#Antimicrobial Prophylaxis for Surgery
ASPLENIA & VALVULAR HEART DISEASE REFERENCES
232 Review of guidelines for the prevention and treatment of infection in patients with an absent or dysfunctional spleen
British Journal of Haematology 2011, 155, 308–317
Davies JM et al http://www.sbp.com.br/pdfs/Review_guidelinesforthepreventionandtreatmentofinfectioninpatientswithaabsentordysfunctionalsp.pdf
89 NICE Prophylaxis Against Infective Endocarditis CG64 NICE NICE http://publications.nice.org.uk/prophylaxis-against-infective-endocarditis-cg64
TRAUMA REFERENCES
470 The Management of Severe Open Lower Limb Fractures (BOAST 4) 2009
BRITISH ORTHOPAEDIC ASSOCIATION & BAPRAS
http://www.boa.ac.uk/LIB/LIBPUB/Documents/BOAST%204%20-%20The%20Management%20of%20Severe%20Open%20Lower%20Limb%20Fractures.pdf
34
SUPPLEMENTARY RESOURCESElement 9 - SURGICAL INFECTION AND PROPHYLAXIS - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
GENERAL SURGICAL INFECTION & PROPHYLAXIS REFERENCES
9 Antibiotic Prescribing for Today's Practitioner (2 hours)
NES NES/LearnPro http://www.nes.scot.nhs.uk/education-and-training/by-theme-initiative/healthcare-associated-infections/online-short-courses/antibiotic-prescribing.aspx
58 Surgical Prophylaxis for gram positive and gram negative infections (30 mins)
BSAC Mark Willox http://www.online-web-presentations.com/SSI/day1/pdf/Mark%20Wilcox.pdf
339 SAPG Guidance on Re-Dosing Antimicrobials for Surgical Prophylaxis
SAPG J Sneddon A MacDonald
http://www.scottishmedicines.org.uk/files/sapg/SAPG_Recommendations_for_Re-dosing_Antibiotics_for_Surgical_Prophylaxis.pdf
233 Infections associated with orthopedic implants (via TKN / Athens login)
Curr Op Infect Dis 2006;19:349-356
Trampuz A et al http://www.knowledge.scot.nhs.uk/
382 Critical Care & Trauma Part 8: Surgical Sepsis Office of International Surgery, U. Toronto
Jackson A et al http://ptolemy.library.utoronto.ca/content/critical-care-and-trauma-part-8-surgical-sepsis
476 Surgical Site Infection Surveillance HPS http://www.hps.scot.nhs.uk/haiic/sshaip/surgicalsiteinfectionsurveillance.aspx
493 NICE Quality Standard QS49 Surgical site infection NICE NICE http://publications.nice.org.uk/surgical-site-infection-qs49
35
Resources for Element 10 Pharmacokinetics (PK) pharmacodynamics (PD) and therapeutic drug monitoring (TDM)CORE RESOURCES
Element 10 - ANTIMICROBIAL PHARMACOKINETICS (PK), PHARMACODYNAMICS (PD) & THERAPEUTIC DRUG MONITORING (TDM) - CORE RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
GENERAL PK, PD AND TDM REFERENCES
103 Therapeutic Drug Monitoring of Antimicrobials via TKN / Athens login)
Br J Pharmacol Roberts JA et al http://onlinelibrary.wiley.com.proxy.knowledgeservices.org/doi/10.1111/j.1365-2125.2011.04080.x/pdf
143 Vancomycin Therapeutic Monitoring: Review and Recommendations from the ASHP, IDSA and SIDP Task Force
Am J Health-Syst Pharm ; 2009 ; 66 : 82 -98
Rybak M et al http://www.idsociety.org/Antimicrobial_Agents/
468 Antimicrobial Pharmacokinetics Webinar Part 1 (26 mins)
NES Alison Thomson https://attendee.gotowebinar.com/recording/4788799007120449538
509 Antimicrobial Pharmacokinetics Webinar Part 2 (40 mins)
NES Alison Thomson https://attendee.gotowebinar.com/recording/1870728132351983618
511 Antimicrobial Pharmacokinetics Webinar Part 3 (42 mins)
NES Alison Thomson https://attendee.gotowebinar.com/recording/7518889677424862209
189 Development of teicoplanin dosage guidelines for patients treated within an (OPAT) programme
JAC (2009) 64 (1): 181-187.
Lamont E et al http://jac.oxfordjournals.org/content/64/1/181.full
273 Development of gentamicin guidelines for synergistic use (via TKN)
ASAP Shared Space Thomson A http://www.elib.scot.nhs.uk/SharedSpace/pharmacy/Uploads/2011/Mar/20110323151742_Gent-dosing_synergy.pdf
335 Antibiotic pharmacokinetic and pharmacodynamic indices : for ASAP (1 hour and 40 mins)
NES Andrew Lovering http://www.nes.scot.nhs.uk/education-and-training/by-discipline/pharmacy/about-nes-pharmacy/educational-resources/resources-by-topic/infectious-diseases/antibiotics/antibiotic-pharmacokinetic-and-pharmacodynamic-indices-for-asap.aspx
383 Pharmacodynamics of antibiotics : focus on outcome & resistance : for ASAP (60 mins)
NES Andrew Lovering http://www.nes.scot.nhs.uk/education-and-training/by-discipline/pharmacy/about-nes-pharmacy/educational-
36
Element 10 - ANTIMICROBIAL PHARMACOKINETICS (PK), PHARMACODYNAMICS (PD) & THERAPEUTIC DRUG MONITORING (TDM) - CORE RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
resources/resources-by-topic/infectious-diseases/antibiotics/pharmacodynamics-of-antibiotics-focus-on-outcome-resistance-for-asap.aspx
59 The impact of recent antimicrobial interventions - the PK/PD debate & what the evidence says (30 mins)
BSAC William Hope http://www.online-web-presentations.com/BSAC_HAVAP2010/
AMINOGLYCOSIDE & GLYCOPEPTIDE REFERENCES
338 Gentamicin and Vancomycin Training Resource (4 hours)
NES/LearnPro Alison Thomson http://www.nes.scot.nhs.uk/education-and-training/by-theme-initiative/healthcare-associated-infections/online-short-courses/gav-gentamicin-and-vancomycin.aspx
395 SAPG Intravenous gentamicin (GG&C and Hartford) & Vancomycin (Continuous & pulsed)
SAPG SAPG http://www.scottishmedicines.org.uk/SAPG/Quality_Improvement/Gentamicin_and_Vancomycin
512 Gentamicin and Vancomycin Dosing in Amputees (Via TKN registration and Athens Password required)
ASAP/TKN Steve McCormick
http://www.elib.scot.nhs.uk/SharedSpace/pharmacy/Pages/Forums/DiscussionTopics.aspx?ContainerID=209407&topicID=3643
SUPPLEMENTARY RESOURCESElement 10 - ANTIMICROBIAL PHARMACOKINETICS (PK), PHARMACODYNAMICS (PD) & THERAPEUTIC DRUG MONITORING (TDM) - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
GENERAL PK, PD AND TDM REFERENCES
396 Examples of dosage regimen design (registration required with RPS - fee)
The Pharmaceutical Journal2004;273:188
Thomson AH http://www.pjonline.com/search/all?filter0=&filter8=Thomson&filter7%5BThe+Pharmaceutical+Journal%5D=The+Pharmaceutical+Journal&filter4=2004&filter5=273&filter6=188&filter2=**ALL**&filter1=**ALL**&x=11&y
37
Element 10 - ANTIMICROBIAL PHARMACOKINETICS (PK), PHARMACODYNAMICS (PD) & THERAPEUTIC DRUG MONITORING (TDM) - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
=11#library-results
397 Why do therapeutic drug monitoring (registration required with RPS - fee)
The Pharmaceutical Journal2004;273:153
Thomson AH http://www.pjonline.com/search/all?filter0=&filter8=Thomson&filter7%5BThe+Pharmaceutical+Journal%5D=The+Pharmaceutical+Journal&filter4=2004&filter5=273&filter6=153&filter2=**ALL**&filter1=**ALL**&x=7&y=12#library-results
398 Variability in drug dosage requirements (registration required with RPS - fee)
The Pharmaceutical Journal2004;272:806
Thomson AH http://www.pjonline.com/search/all?filter0=&filter8=Thomson&filter7%5BThe+Pharmaceutical+Journal%5D=The+Pharmaceutical+Journal&filter4=2004&filter5=272&filter6=806&filter2=**ALL**&filter1=**ALL**&x=7&y=11#library-results
399 Back to basics: pharmacokinetics (registration required with RPS - fee)
The Pharmaceutical Journal2004;272:769
Thomson AH http://www.pjonline.com/search/all?filter0=&filter8=&filter7%5BThe+Pharmaceutical+Journal%5D=The+Pharmaceutical+Journal&filter4=2004&filter5=272&filter6=769&filter2=**ALL**&filter1=**ALL**&x=15&y=10
400 Bespoke pharmacy: Tailoring medicines to the needs of patients - the role of therapeutic drug monitoring (registration required with RPS - fee)
Hospital Pharmacist2003;10:160
Thomson AH http://www.pjonline.com/search/all?filter0=&filter8=omson&filter7%5BHospital+Pharmacist%5D=Hospital+Pharmacist&filter4=2003&filter5=10&filter6=160&filter2=**ALL**&filter1=**ALL**&x=10&y=10
235 Continuous v intermittent infusions of antibiotics for the treatment of severe acute infections (via TKN / Athens login)
Cochrane Database Syst Rev 2013(3) Art No CD008481
Shiu J et al http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008481.pub2/abstract
PK IN SPECIAL PATIENT GROUPS REFERENCES
512 Gentamicin and Vancomycin Dosing in Amputees (Via ASAP/TKN Steve http://www.elib.scot.nhs.uk/SharedSpace/pharmacy/
38
Element 10 - ANTIMICROBIAL PHARMACOKINETICS (PK), PHARMACODYNAMICS (PD) & THERAPEUTIC DRUG MONITORING (TDM) - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
TKN registration and Athens Password required) McCormick Pages/Forums/DiscussionTopics.aspx?ContainerID=209407&topicID=3643
441 UKCPA Drug Dosing in Extremes of Body Weight in Critically Ill Patients 2013
UKCPA http://www.nes.scot.nhs.uk/media/2536057/vt3_drug_dosing_ukcpa_doc__for_resources__website__jan_2014.pdf
502 How should antibiotics be dosed in obesity? UKMI Q&A 378.1
NICE Evidence UKMI https://www.evidence.nhs.uk/topic/obesity?om=%5B%7B%22srn%22%3A%5B%22%20ukmi%20%22%5D%7D%5D
100 Dosing of Antibiotics in Obesity (via TKN / Athens login)
Current Opinion in Infectious Diseases
Janson B, Thursky K
http://www.knowledge.scot.nhs.uk/home/search-results.aspx?q=publicid%3a%22OVIDmedl%7c23041773%22&pm=fql&expand=true&portal=
518 Altered vancomycin pharmacokinetics in obese and morbidly obese patients: what we have learned over J Antimicrob Chemother. 2012;67(6):1305-10.the past 30 years
J Antimicrob Chemother. 2012;67(6):1305-10.
Grace E http://jac.oxfordjournals.org/content/67/6/1305.long
456 Clinical Pharmacokinetics of Penicillins, Cephalosporins and Aminoglycosides in the Neonate
Pharmaceuticals 2010; 3 (8): 2568-2591.
Pacifici, G.M http://www.mdpi.com/1424-8247/3/8/2568
457 Clinical pharmacokinetics of vancomycin in the neonate: a review
Clinics (Sao Paulo). 2012 July; 67(7): 831–837
Pacifici GM Allegaert K
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400177/
237 Antibiotic dosing in critical illness J Antimicrob Chemother 2011;66 S2ii23-ii31
MacKenzie C et al
http://jac.oxfordjournals.org/content/66/suppl_2/ii25.long
525 Pharmacokinetic issues for antibiotics in the critically ill patient
Crit Care Med 2009; 37(3): 840 - 851
Roberts JA et al http://clinicalevidence.pbworks.com/w/file/fetch/55562374/REVISION%20GENERALIDADES%20ANTIBIOTICOS.pdf
514 Influence of multiple courses of therapy on aminoglycoside clearance in adult patients with
J. Antimicrob. Chemother. (2013)
Alghanem S et al http://jac.oxfordjournals.org/content/68/6/1338.full.pdf+html?hwoaspck=true
39
Element 10 - ANTIMICROBIAL PHARMACOKINETICS (PK), PHARMACODYNAMICS (PD) & THERAPEUTIC DRUG MONITORING (TDM) - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
cystic fibrosis 68 (6): 1338-1347
515 Population pharmacokinetics of tobramycin in patients with and without cystic fibrosis (via TKN/Athens login)
Clinical Pharmacokinetics 2013 52 (4): 289-301
Hennig S et al www.knowledge.scot.nhs.uk/
516 Pharmacokinetic and pharmacodynamic optimisation of intravenous tobramycin dosing among children with cystic fibrosis. (via TKN/Athens login)
J pharmacokinet pharmacodynam 2014;41(1): 71-79
Sherwin CMT et al
www.knowledge.scot.nhs.uk/
517 Once versus three-times daily regimens of tobramycin treatment for pulmonary exacerbations of cystic fibrosis--the TOPIC study: a randomised controlled trial (via TKN/Athens login)
Lancet. 2005;365(9459):573-8
Smyth A et al www.knowledge.scot.nhs.uk/
519 Dose optimisation of antibiotics in children: application of pharmacokinetics/pharmacodynamics in paediatrics (via TKN/Athens login)
Int J Antimicrobial Agents; 43(3): 223-230
Downes KJ et al www.knowledge.scot.nhs.uk/
520 Pharmacokinetics in children Merck Manual Online Merck http://www.merckmanuals.com/professional/pediatrics/principles_of_drug_treatment_in_children/pharmacokinetics_in_children.html
521 Pharmacokinetics in the Elderly Merck Manual Online Merck http://www.merckmanuals.com/professional/geriatrics/drug_therapy_in_the_elderly/pharmacokinetics_in_the_elderly.html
522 Unique Aspects of Antimicrobial Use in Older Adults Clin Infect Dis. (2005) 40 (7): 997-1004.
Faulkener CM et al
http://cid.oxfordjournals.org/content/40/7/997.long
523 Optimal Dosing Design for Antibiotic Therapy in the Elderly: A Pharmacokinetic and Pharmacodynamic Perspective
Recent Pat Anti-Infec Drug Disc 2008;3:45-52
Noreddin A et al http://www.eurekaselect.com/82160/article
524 Pharmacokinetics and Safety of Antimicrobial Agents During Pregnancy (old article for background info only - refer to local guidelines re drug dosing etc)
Rev Inf Dis 1985; 7(3): 287-313
Chow AW, Jeweson PJ
http://www.amchp.org/programsandtopics/womens-health/CDC/ANTIBIOTICS/Chow.pdf
40
Element 10 - ANTIMICROBIAL PHARMACOKINETICS (PK), PHARMACODYNAMICS (PD) & THERAPEUTIC DRUG MONITORING (TDM) - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
526 Pharmacokinetics in pregnancy Best Prac & Res Clin Obs & Gyn 2001; 15(6): 819-26
Dawes M Chowienczyk PJ
http://analysis3.com/download.php?id=14636
PK, PD & TDM WITH OTHER DRUG GROUPS
503 Therapeutic drug monitoring (TDM) of antifungal agents: guidelines from the British Society for Medical Mycology
J Antimicrob Chemother (2013) doi: 10.1093/jac/dkt508
Ashbee HR et al http://jac.oxfordjournals.org/content/early/2013/12/28/jac.dkt508.full?hwoaspck=true&sid=94fb36c1-9153-44c8-b5a5-bddaddddb708
480 Optimizing antifungal choice and administration (via TKN / Athens login)
Curr Med Research Opin. 29, Sup 4, 2013, 13–18
Andes D http://informahealthcare.com.proxy.knowledgeservices.org/doi/pdf/10.1185/03007995.2012.761135
481 Sequential treatment of cytomegalovirus infection or disease with a short course of intravenous ganciclovir followed by oral valganciclovir: efficacy. safety, and pharmacokinetics (via TKN / Athens login)
Transpl Infect Dis 2010: 12: 204-212
Caldes A et al www.knowledge.scot.nhs.uk /
482 Analysis Relationships Between Pharmacokinetic Parameters in silico/in vivo of Selected Antiviral Drugs Based on Structural Analysis
Adv Clin Exp Med 2008, 17, 3, 285–292
Grabowski T et al
http://www.advances.am.wroc.pl/pdf/2008/17/3/285.pdf
483 The Role of Therapeutic Drug Monitoring in the Management of Patients With Human Immunodeficiency Virus Infection (via TKN / Athens login)
Therapeutic Drug Monitoring. 33 (3):265-74 2011
Pretorius E et al www.knowledge.scot.nhs.uk /
41
Resources for Element 11 Data analysis and presentation Incorporating interpretation of audit dataCORE RESOURCESElement 11 - DATA ANALYSIS AND PRESENTATION INCORPORATING INTERPRETATION OF AUDIT DATA - CORE RESOURCES
Resource ID Name of resourceResource owner Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
446 Introduction to routine data for ASAP (16 mins)
NES Vicky Elliott https://attendee.gotowebinar.com/recording/7181743125700807938
472 Basic statistics for ASAP (17 mins) NES Vicky Elliott https://attendee.gotowebinar.com/recording/6376940196590164993
473 Data for quality improvement for ASAP (14 mins)
NES Andrea Patton https://attendee.gotowebinar.com/recording/4826215385075476226
474 Utilising and presenting data from routine sources for ASAP (18 mins)
NES Vicky Elliott https://attendee.gotowebinar.com/recording/6282428376111341058
475 Introduction to Control Charts and Statistical Process Control (SPC) for ASAP (16 mins)
NES Gwen Bayne https://attendee.gotowebinar.com/recording/4981498315782606082
507 Presenting Data NES Gwen Bayne https://attendee.gotowebinar.com/recording/3571299886369227010
508 The Power of Local Data for ASAP (20 mins)
NES Frances Kerr? Still to be recorded
494 Surgical Prophylaxis Indicator Report SAPG http://www.scottishmedicines.org.uk/files/sapg/Surgical_Prophylaxis_Indicator_Report_October_2013.pdf
495 National Services Scotland Annual Report
NHS National Services Scotland
http://www.nhsnss.org/pages/publications/annual_reports.php
SUPPLEMENTARY RESOURCES
42
Element 11 - DATA ANALYSIS AND PRESENTATION INCORPORATING INTERPRETATION OF AUDIT DATA - SUPPLEMENTARY RESOURCE
Resource ID Name of resource Resource ownerPresenter/Author URL link direct to resource
Date Resource Accessed/ Comments
7 Patterns of Antimicrobial Use and Resistance in Scotland(MSc) (56 mins)
NES William Malcolm http://www.video3uk.com/login.aspx
53 Antimicrobial resistance surveillance, improving relevance and outputs 20 mins)
BSAC Prof Alasdair McGowan
http://bsac.org.uk/events/past-events-2011/spring-meeting-agm-2011/spring-meeting-2011/
109 From intermittent antibiotic point prevalence surveys to quality improvement: experience in Scottish hospitals
Antimicrob Res Inf Cont 2013;2:3
Malcolm W et al http://www.aricjournal.com/content/2/1/3
447 Excel 2007 training course Microsoft office http://office.microsoft.com/en-us/training/excel-2007-training-courses-HA010218987.aspx?CTT=5&origin=HA010225533
43
Resources for Element 12 Meningitis and CNS InfectionCORE RESOURCES
Element 12 - MENINGITIS AND CNS INFECTION - CORE RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
MENINGITIS REFERENCES
35 Management of Invasive Meningococcal Disease in Children & Young People (2008) SIGN 102
SIGN http://www.sign.ac.uk/guidelines/fulltext/102/index.html
77 Bacterial meningitis and meningococcal septicaemia: Management of bacterial meningitis and meningococcal septicaemia in children and young people younger than 16 years in primary and secondary care CG102 2010
NICE NICE http://publications.nice.org.uk/bacterial-meningitis-and-meningococcal-septicaemia-cg102
147 Practice Guidelines for the Management of Bacterial Meningitis(This covers adults whereas UK documents just up to 16 years)
Clin Infect Dis ; 2004 ; 39 : 1267 -1284
Tunkel AR et al http://www.idsociety.org/Organ_System/#Central Nervous System (CNS)
393 Guidance for public health management of meningococcal disease in the UK
HPA http://www.hpa.org.uk/webc/HPAwebFile/HPAweb_C/1194947389261
450 Early management of suspected bacterial meningitis and meningococcal septicaemia in adults
Journal of Infection 2003; 46: 75-77
Heyderman RS et al
http://www.britishinfection.org/drupal/sites/default/files/meningitisJI2003.pdf
451 Early management of suspected bacterial meningitis and meningococcal septicaemia in adults algorithm
BIS BIS http://www.britishinfection.org/drupal/sites/default/files/MeningitisAlgorithm03.pdf
496 Viral Meningitis (via TKN) Dynamed http://web.ebscohost.com/dynamed/detail?sid=bdc5104f-6727-41be-bbc3-c4bad5b4ed6a%40sessionmgr113&vid=1&hid=123&bdata=JnNpdGU9ZHluYW1lZC1saXZlJnNjb3BlPXNpdGU%3d#db=dme&AN=114531
ENCEPHALITIS REFERENCES
452 Management of suspected viral encephalitis in adults Journal of Infection Solomon T et al http://www.journalofinfection.com/article/S0163-
44
Element 12 - MENINGITIS AND CNS INFECTION - CORE RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
– Association of British Neurologists and British Infection Association National Guidelines
2012; 64(4);347-73 4453(11)00563-9/fulltext
OTHER CNS INFECTION REFERENCES - SEE SUPPLEMENTARY RESOURSES SECTION
SUPPLEMENTARY RESOURCESElement 12 - MENINGITIS AND CNS INFECTION - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
GENERAL CNS INFECTION REFERENCES
284 SWAB Guidelines on Antibacterial Therapy of Patients with Bacterial Central Nervous System Infections
SWAB Dutch Working Party on Antimicrobial Policy
http://www.swab.nl/swab/cms3.nsf/uploads/FE54A057082AA54CC1257A2B00293B1D/$FILE/SWAB_CNSguideline_%20June12.pdf
MENINGITIS REFERENCES
82 Bacterial Meningitis and meningococcal sepatcaemia in children and young people (QS19)
NICE NICE http://publications.nice.org.uk/quality-standard-for-bacterial-meningitis-and-meningococcal-septicaemia-in-children-and-young-qs19
448 Antibiotics for preventing meningococcal infections (via TKN / Athens login)
CDSR 2013, Issue 10. Art. No.: CD004785
Trestioreanu A Z et al
http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD004785.pub5/abstract
394 Lessons from research for doctors in training: recognition and early management of meningococcal disease in children and young people 3rd Ed
Meningitis research foundation
http://www.meningitis.org/health-professionals/doctors-in-training
45
Element 12 - MENINGITIS AND CNS INFECTION - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
449 Cerebrospinal fluid lactate concentration to distinguish bacterial from aseptic meningitis: a systematic review and meta analysis (Structured abstract) (via TKN / ‐Athens login)
Cochrane DARE 2011 Issue 3
Huy Ntet al http://onlinelibrary.wiley.com/o/cochrane/cldare/articles/DARE-12011001453/frame.html
ENCEPHALITIS REFERENCES
148 The Management of Encephalitis: Clinical Practice Guidelines
Clin Infect Dis 2008 ; 47 : 303 -327
Tunkel AR et al http://www.idsociety.org/Organ_System/#Central Nervous System (CNS)
OTHER CNS INFECTION REFERENCES
167 The Clinical Assessment, Treatment, and Prevention of Lyme Disease, Human Granulocytic Anaplasmosis, and Babesiosis
Clin Infect Dis 2006 ; 43 : 1089 -1134
Wormser GP et al
http://www.idsociety.org/Organism/
454 British Infection Society guidelines for the diagnosis and treatment of tuberculosis of the central nervous system in adults and children
Journal of Infection (2009) 59, 167-187
Thwaites G et al http://www.britishinfection.org/drupal/sites/default/files/CNS%20TB%202009%20Thwaites.pdf
234 The rational use of antibiotics in the treatment of brain abscess (via TKN / Athens login)
Br J Neurosurg 2000;14(6):525-30
Louvois J et al http://www.cwmicrobiology.nhs.uk/NeuroPDFs/brain_abscess.pdf
168 Practice Parameter: Treatment of Nervous System Lyme Disease (AAN)" (Endorsed by IDSA)
Neurology ; 2007 ; 69 : 91 -102
Halperin JJ et al http://www.idsociety.org/Organism/
46
Resources for Element 13 Endocarditis and Cardiovascular Infection CORE RESOURCES
Element 13 - ENDOCARDITIS AND CARDIOVASCULAR INFECTION - CORE RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
GENERAL ENDOCARDITIS REFERENCES
Local antimicrobial guidelines on the treatment of infective endocarditis
89 Prophylaxis Against Infective Endocarditis CG64 2008 NICE NICE http://publications.nice.org.uk/prophylaxis-against-infective-endocarditis-cg64
202 Guidelines for the diagnosis and antibiotic treatment of endocarditis in adults: a report of the Working Party of BSAC
J. Antimcrob.Chemother., Feb 2012; 67:269-289
Gould FK et al http://jac.oxfordjournals.org/content/early/2012/02/13/jac.dks039.full
289 Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009)
(one year more recent than NICE CG 64 so possibly CORE)
European Heart Journal 2009;30(19):2369-2413
ESC Guideline http://eurheartj.oxfordjournals.org/content/30/19/2369.full
CARDIOVASCULAR IMPLANTABLE ELECTRONIC DEVICE INFECTION REFERENCES
145 Cardiovascular Implantable Electronic Device Infections
Circulation ; 2010 ; 121 : 458 -477
Baddour LM http://www.idsociety.org/Organ_System/
47
SUPPLEMENTARY RESOURCESElement 13 - ENDOCARDITIS AND CARDIOVASCULAR INFECTION - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
GENERAL ENDOCARDITIS REFERENCES
311 Infective Endocarditis Clinical Vignette(04) NB refer to local guidelines for specific drug therapy - good for background information only) (2 hours)
PAUSE BSAC http://www.pause-online.org.uk
206 Guidelines for the prevention of endocarditis: report of the Working Party of the British Society for Antimicrobial Chemotherapy 2006 (cited in NICE CG64)
J Antimicrob Chemother 2006; 57:1034-42
Gould FK et al http://jac.oxfordjournals.org/content/57/6/1035.full.pdf
288 Infective endocarditis (via TKN / Athens login) N Engl J Med 2013; 368(15):1425-33
Hoen B et al http://www.knowledge.scot.nhs.uk/home/search-results.aspx?q=publicid:%22OVIDmedl|23574121%22&pm=fql&expand=true&portal=
48
Resources for Element 14 Bone & Joint InfectionsCORE RESOURCES
Element 14 - BONE AND JOINT INFECTION - CORE RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
GENERAL BONE & JOINT INFECTION REFERENCES
92 Diabetic Foot Problems CG119 NICE NICE http://publications.nice.org.uk/diabetic-foot-problems-cg119
116 Use of antibiotics in people with diabetic foot disease - a consensus statement
The Diabetic Foot Journal Vol 12 No 2 2009
Leese G et al http://www.scottishmedicines.org.uk/files/sapg/Use_of_Antibiotics_in_people_with_diabetic_foot_disease_-_Consensus_Statement_-_2009.pdf
163 Diagnosis and Management of Prosthetic Joint Infection: Clinical Practice Guidelines by the Infectious Diseases Society of America
Clinical Infectious Diseases ; 2013 ; 56 : 1 -25
Osmon DR et al http://www.idsociety.org/Organ_System/#Skeletal (Bones & Joints)
260 Bacterial septic arthritis in adults (via TKN / Athens login)
Lancet 2010;375: 846-55
Matthews CJ http://www.sciencedirect.com/science/article/pii/S0140673609615956
433 Treating infections in Bone & Joint in acute and OPAT settings
NES Andrew Seaton
INTERACTION AND ADR REFERENCES
442 Stockley's Drug Interactions Medicines Complete http://www.medicinescomplete.com/mc/stockley/current/
443 Electronic Medicines Compendium eMC Datapharm http://www.medicines.org.uk/emc/
SUPPLEMENTARY RESOURCESElement 14 - BONE AND JOINT INFECTION - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
GENERAL BONE & JOINT INFECTION REFERENCES
49
Element 14 - BONE AND JOINT INFECTION - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
233 Infections associated with orthopedic implants (via TKN / Athens login)
Curr Op Infect Dis 2006;19:349-356
Trampuz A et al http://www.knowledge.scot.nhs.uk/
259 Prosthetic Joint Associated Infections (via TKN / Athens login)
Best Prac Res Clin Rheumatol 2006;20(6):1045
Zimmerli W http://www.bprclinrheum.com/article/S1521-6942(06)00107-0/abstract
321 Septic Arthritis Clinical Vignette (14) (free registration for HCPs) (2 hours)
PAUSE BSAC http://www.pause-online.org.uk
50
Resources for Element 15 Gastrointestinal (GI) infectionsCORE RESOURCES
Element 15 - GASTROINTESTINAL (GI) INFECTION - CORE RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
GENERAL GI INFECTION REFERENCES
157 Guidelines for the Selection of Anti-infective Agents for Complicated Intra-abdominal Infections
Clin Infect Dis 2010 ; 501 : 133 -164
Solomkin JS http://www.idsociety.org/Organ_System/#Intra-Abdominal
Local Antimicrobial Prescribing Guidelines on the eradication of H pylori and other GI infections
290 EASL clinical practice guidelines on the management of ascites, spontaneous bacterial peritonitis, and hepatorenal syndrome in cirrhosis (via TKN / Athens login)
Journal of Hepatology 2010;53(3):397-417
European Association for the Study of the Liver
http://www.sciencedirect.com/science/article/pii/S0168827810004782
PERITONITIS REFERENCES
291 Spontaneous Bacterial peritonitis: recent guidelines and beyond (via TKN / Athens login)
GUT 2012;61:297-310
Weist R et al http://gut.bmj.com/content/61/2/297.full
HELICOBACTER PYLORI REFERENCES
497 Test and treat for Helicobacter pylori (HP) in Dyspepsia Quick Reference Guide for Primary Care
British Infection Association
BIA http://www.britishinfection.org/drupal/sites/default/files/files/Helicobacter%20guidance%20final%20for%20web%2027_06_12.pdf
INFECTIOUS DIARRHOEA REFERENCES
477 Guidelines for the management of norovirus outbreaks in acute and community health and social care settings 2012
BIA BIA http://www.britishinfection.org/drupal/sites/default/files/files/Norovirus%20report.pdf
490 Diarrhoea and vomiting in children NICE CG 84 2009 NICE NICE http://publications.nice.org.uk/diarrhoea-and-vomiting-in-children-cg84
379 Immunisation against infectious disease: the Green Department of https://www.gov.uk/government/organisations/public-
51
Element 15 - GASTROINTESTINAL (GI) INFECTION - CORE RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
Book (Rotavirus) Health health-england/series/immunisation-against-infectious-disease-the-green-book
340 Travax (travelers' diarrhoea) (free registration required)
Health Protection Scotland
http://www.travax.nhs.uk/
PANCREATITIS REFERENCES
318 Pancreatitis Clinical Vignette (11) (free registration for HCPs) (60 mins)
PAUSE BSAC http://www.pause-online.org.uk
SUPPLEMENTARY RESOURCESElement 15 - GASTROINTESTINAL (GI) INFECTION SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
HELICOBACTER PYLORI REFERENCES
405 Evidence-based guidelines from ESPGHAN and NASPGHAN for Helicobacter pylori infection in children
J Ped Gastro Nutr 2011 ;53(2):230-43
Koletzko S et al http://www.naspghan.org/user-assets/Documents/pdf/PositionPapers/H%20pylori%20-%20PAP%20version.pdf
94 Dyspepsia (inc H Pylori) SIGN 68 2003 SIGN http://www.sign.ac.uk/guidelines/fulltext/68/index.html
INFECTIOUS DIARRHOEA REFERENCES
151 Practice Guidelines for the Management of Infectious Diarrhea
Clin Infect Dis 2001 ; 32 : 331 -350
Guerrant RL et al http://www.idsociety.org/Organ_System/#Gastrointestinal (GI)
254 Cryptosporidiosis and its treatment CDC http://www.cdc.gov/parasites/crypto/health_professionals/tx.html
255 Diagnosis and treatment of amebiasis Clin Infect Dis Petri WA http://cid.oxfordjournals.org/content/29/5/1117.full
52
Element 15 - GASTROINTESTINAL (GI) INFECTION SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
1999;29:1117-25
BILIARY INFECTIONS REFERENCES
458 Diagnosis and Management of Primary Sclerosing Cholangitis
HEPATOLOGY 2010; 51(2): 660-78
Chapman R et al http://www.aasld.org/practiceguidelines/Documents/Practice%20Guidelines/PSC_2-2010.pdf
53
Resources for Element 16 - Antibiotics used in pregnancy, neonates and paediatrics CORE RESOURCES
Element 16 - ANTIBIOTICS USED IN PREGNANCY, NEONATES AND PAEDIATRICS - CORE RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
PREGNANCY & LACTATION REFERENCES
238 Toxbase Monographs for drugs in pregnancy and breastfeeding (free registration for healthcare professionals - one registration per pharmacy)
Toxbase http://www.toxbase.org/
240 Sepsis in Pregnancy, Bacterial (Green-top 64a) 2012 RCOG http://www.rcog.org.uk/womens-health/clinical-guidance/sepsis-pregnancy-bacterial-green-top-64a
241 Sepsis following Pregnancy, Bacterial (Green-top 64b) 2012
RCOG http://www.rcog.org.uk/womens-health/clinical-guidance/sepsis-following-pregnancy-bacterial-green-top-64b
43 Management of Suspected Bacterial Urinary Tract Infections in Adults (updated 2012) SIGN 88
SIGN http://www.sign.ac.uk/guidelines/fulltext/88/index.html
478 Lactmed US National Library of Medicine
http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT
479 Medications and Mothers' Milk 2012 if available Hale Publishing Hale T
491 NICE CG37 Postnatal care (also covers neonates) NICE NICE http://publications.nice.org.uk/postnatal-care-cg37
492 Antibiotics for mastitis in breastfeeding women (via TKN / Athens login)
Jahanfar S, Ng CJ, Teng CL
Cochrane Database of Systematic Reviews 2013, Issue 2. Art. No.: CD005458
http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD005458.pub3/abstract;jsessionid=1A612ACABA2A10EC5B2BEFE9CDFEF885.f01t03
376 Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk 9th ed (via TKN)
Lippincott Williams & Wilkins
Briggs G http://www.knowledge.scot.nhs.uk /
524 Pharmacokinetics and Safety of Antimicrobial Agents During Pregnancy (old article for background info
Rev Inf Dis 1985; 7(3): 287-313
Chow AW, Jeweson PJ
http://www.amchp.org/programsandtopics/womens-health/CDC/ANTIBIOTICS/Chow.pdf
54
Element 16 - ANTIBIOTICS USED IN PREGNANCY, NEONATES AND PAEDIATRICS - CORE RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
only - refer to local guidelines re drug dosing etc)
NEONATE REFERENCES
83 Antibiotics in Early Onset Neonatal Infection CG149 NICE NICE http://publications.nice.org.uk/antibiotics-for-early-onset-neonatal-infection-cg149
440 Neonatal Formulary (6th ED) with updates 2011 (if available)
Wiley Hey E (Editor) http://www.neonatalformulary.com/default.asp
PAEDIATRIC REFERENCES
195 British Thoracic Society guidelines for the management of community acquired pneumonia in children: update 2011
Thorax 2011;66 (2) Harris M et al http://www.brit-thoracic.org.uk/guidelines-and-quality-standards/community-acquired-pneumonia-in-children-guideline/
462 Cystic Fibrosis Foundation evidence-based guidelines for management of infants with cystic fibrosis (US guidance) (via TKN / Athens login)
J Pediatr. 2009 Dec;155(6 Suppl):S73-93.
Borowitz D et al http://www.guideline.gov/content.aspx?f=rss&id=43789
375 British National Formulary for Children (BNF-C) BMJ/RPS http://www.medicinescomplete.com/about/index.htm
77 Bacterial meningitis and meningococcal septicaemia: Management of bacterial meningitis and meningococcal septicaemia in children and young people younger than 16 years in primary and secondary care CG102 (2010)
NICE NICE http://publications.nice.org.uk/bacterial-meningitis-and-meningococcal-septicaemia-cg102
407 Bronchiolitis in children (2006) SIGN 91 SIGN SIGN http://www.sign.ac.uk/guidelines/fulltext/91/index.html
498 NICE CG 132 Guidance on Caesarian section NICE NICE http://publications.nice.org.uk/caesarean-section-cg132
91 Bronchiolitis in Children CG DRAFT NICE NICE http://guidance.nice.org.uk/
35 Management of Invasive Meningococcal Disease in Children & Young People (2008) SIGN 102
SIGN SIGN http://www.sign.ac.uk/guidelines/fulltext/102/index.html
71 Feverish Illness in Children CG160 NICE NICE http://publications.nice.org.uk/feverish-illness-in-children-
55
Element 16 - ANTIBIOTICS USED IN PREGNANCY, NEONATES AND PAEDIATRICS - CORE RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
cg160
74 Urinary Tract Infection in Children CG54 NICE NICE http://publications.nice.org.uk/urinary-tract-infection-in-children-cg54
38 Management of Sore Throat and Indication for Tonsillectomy (2010) SIGN 117
SIGN SIGN http://www.sign.ac.uk/guidelines/fulltext/117/index.html
506 Introduction to paediatric pharmaceutical care (use generic sections and chapter on childhood infection)
NES NES http://www.nes.scot.nhs.uk/education-and-training/by-discipline/pharmacy/about-nes-pharmacy/educational-resources/resources-by-topic/child-health/introduction-to-paediatric-pharmaceutical-care.aspx
SUPPLEMENTARY RESOURCESElement 16 - ANTIBIOTICS USED IN PREGNANCY, NEONATES AND PAEDIATRICS - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
PREGNANCY & LACTATION REFERENCES
402 Preterm Prelabour Rupture of Membranes (Green Top 44)
RCOG http://www.rcog.org.uk/files/rcog-corp/GTG44PPROM28022011.pdf
404 Recommended strategies for Intrapartum Antimicrobial Prophylaxis (IAP) for Perinatal Group B Streptococcal Disease.
perinatology.com http://www.perinatology.com/protocols/GBS.htm
211 Timing of prophylactic antibiotics for preventing postpartum infectious morbidity in women undergoing cesarean delivery (Protocol) (via TKN / Athens login)
CDSR 2011, Issue 12. Art. No.: CD009516
Baxter JK et al http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD009516/full
239 Antibacterial medication use during pregnancy and Arch Pediat Adolesc Crider KS et al http://archpedi.jamanetwork.com/article.aspx?
56
Element 16 - ANTIBIOTICS USED IN PREGNANCY, NEONATES AND PAEDIATRICS - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
risk of birth defects Med 2009;163(11):978-85
articleid=382406
455 Antibiotic Use in Pregnancy and Lactation OBSTETRICS & GYNECOLOGY 2006; 107(5): 1120-38
Nahum GG et al http://www.amchp.org/programsandtopics/womens-health/CDC/ANTIBIOTICS/Nahum.pdf
246 Group B Streptococcal Disease, Early Onset (Green-top 36) 2012
RCOG http://www.rcog.org.uk/womens-health/clinical-guidance/prevention-early-onset-neonatal-group-b-streptococcal-disease-green-
247 Genital Herpes in Pregnancy, Management (Green-top 30) 2007
RCOG http://www.rcog.org.uk/womens-health/clinical-guidance/management-genital-herpes-pregnancy-green-top-30
248 Chickenpox in Pregnancy (Green-top 13) 2007 RCOG http://www.rcog.org.uk/womens-health/clinical-guidance/chickenpox-pregnancy-green-top-13
526 Pharmacokinetics in pregnancy Best Prac & Res Clin Obs & Gyn 2001; 15(6): 819-26
Dawes M Chowienczyk PJ
http://analysis3.com/download.php?id=14636
524 Pharmacokinetics and Safety of Antimicrobial Agents During Pregnancy (old article for background info only - refer to local guidelines re drug dosing etc)
Rev Inf Dis 1985; 7(3): 287-313
Chow AW, Jeweson PJ
http://www.amchp.org/programsandtopics/womens-health/CDC/ANTIBIOTICS/Chow.pdf
NEONATE REFERENCES
285 Management of antibiotic-resistant infection in the newborn (via TKN / Athens login)
Arch Dis Child Educ Pract Ed 2011;96:122-127
Gray JW et al http://ep.bmj.com/content/96/4/122.full
287 Improving antibiotic prescribing in neonatal units: time to act (via TKN / Athens login)
Arch Dis Child Fetal Neonat Ed 2012;97:F141-F146
Bedford Russell A
http://fn.bmj.com/content/97/2/F141.full
457 Clinical pharmacokinetics of vancomycin in the Clinics (Sao Paulo). Pacifici GM http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400177/
57
Element 16 - ANTIBIOTICS USED IN PREGNANCY, NEONATES AND PAEDIATRICS - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
neonate: a review 2012 July; 67(7): 831–837
Allegaert K
403 Recommendations for the Prevention of Perinatal Group B Streptococcal (GBS) Disease Policy Statement American Academy of Paediatrics 2011
PEDIATRICS 2011.128 (3): 1-6
http://pediatrics.aappublications.org/content/early/2011/07/28/peds.2011-1466.full.pdf
456 Clinical Pharmacokinetics of Penicillins, Cephalosporins and Aminoglycosides in the Neonate
Pharmaceuticals 2010; 3 (8): 2568-2591.
Pacifici, G.M http://www.mdpi.com/1424-8247/3/8/2568
PAEDIATRIC REFERENCES
408 Guidelines on Paediatric Urology (European Association of Urology 2012)
EAU Tekgul S et al http://www.uroweb.org/gls/pdf/21_Paediatric_Urology_LR_August%202012.pdf
411 Recommendations for treatment of childhood non-severe pneumonia (via TKN / Athens login)
Lancet Infect Dis 2009;9: 185-96
Grant GB et al http://blog.utp.edu.co/maternoinfantil/files/2010/08/Guia_Lancet_Neumonia_severa.pdf
412 Antibiotics for acute otitis media in children (Review) Jan2013 (via TKN / Athens login)
Cochrane Venekamp RP et al
http://summaries.cochrane.org/CD000219/antibiotics-for-middle-ear-infection-acute-otitis-media-in-children
453 Management of suspected viral encephalitis in children – Association of British Neurologists and British Paediatric Allergy, Immunology and Infection Group National Guidelines
Journal of Infection 2012; 64(5); 449-77
Kneen R et al http://www.journalofinfection.com/article/S0163-4453(11)00562-7/fulltext
95 Cystic fibrosis (pseudomonas lung infection) - colistimethate sodium and tobramycin TA276 (2013)
NICE NICE http://publications.nice.org.uk/colistimethate-sodium-and-tobramycin-dry-powders-for-inhalation-for-treating-pseudomonas-lung-ta276
490 Diarrhoea and vomiting in children NICE CG 84 2009 NICE NICE http://publications.nice.org.uk/diarrhoea-and-vomiting-in-children-cg84
366 Atopic eczema in children: Management of atopic eczema in children from birth up to the age of 12 years
NICE NICE http://publications.nice.org.uk/atopic-eczema-in-children-cg57
58
Element 16 - ANTIBIOTICS USED IN PREGNANCY, NEONATES AND PAEDIATRICS - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
406 Guidelines on the Management of Acute and Chronic Peritoneal Dialysis
Scottish Paediatric Renal and Urology Network
Renal Unit, Yorkhill
http://www.clinicalguidelines.scot.nhs.uk/Renal%20Unit%20Guidelines/YOR-REN-030%20Management%20of%20Acute%20and%20Chronic%20Peritoneal%20Dialysis%20Oct%2010%20Revision%201.pdf
198 BTS guidelines for the management of pleural infection in children
Thorax 2005;60(Suppl I):i1–i21
Balfour-Lynne IM
http://www.brit-thoracic.org.uk/guidelines-and-quality-standards/pleural-infection-in-children/
516 Pharmacokinetic and pharmacodynamic optimisation of intravenous tobramycin dosing among children with cystic fibrosis.
J pharmacokinet pharmacodynam 2014;41(1): 71-79
Sherwin CMT et al
www.knowledge.scot.nhs.uk/
519 Dose optimisation of antibiotics in children: application of pharmacokinetics/pharmacodynamics in paediatrics (via TKN/Athens login)
Int J Antimicrobial Agents; 43(3): 223-230
Downes KJ et al www.knowledge.scot.nhs.uk/
520 Pharmacokinetics in children Merck Manual Online Merck http://www.merckmanuals.com/professional/pediatrics/principles_of_drug_treatment_in_children/pharmacokinetics_in_children.html
59
Resources for Element 17 Sexually transmitted infection (STI), human immunodeficiency virus (HIV) & other blood borne virus (BBV) CORE RESOURCES
Element 17 - STI, HIV AND OTHER BBV - CORE RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
GENERAL STI/BBV/HIV REFERENCES
64 HIV-STI Pathology (free registration for HCPs) (90 minutes)
e-Learning for Health NHS http://www.e-lfh.org.uk/home/
STI REFERENCES
40 Management of Genital Chlamidia tracomatis Infection (2009) SIGN 109
SIGN http://www.sign.ac.uk/guidelines/fulltext/109/index.html
417 Sexually Transmitted Infections in Primary Care (although primary care is good summary document)
BASSH http://www.bashh.org/documents/Sexually%20Transmitted%20Infections%20in%20Primary%20Care%202013.pdf
65 HIV-STI Bacterial STIs and related conditions (free registration required for HCPs) (2 hours and 30 mins)
e-Learning for Health NHS http://www.e-lfh.org.uk/home/
66 HIV-STI Genital Ulcer Disease (including syphilis) (free registration required for HCPs) (60 mins)
e-Learning for Health NHS http://www.e-lfh.org.uk/home/
413 UK National Guideline for the Management of Pelvic Inflammatory Disease 2011
BASSH http://www.bashh.org/documents/3572.pdf
BBV REFERENCES
68 HIV-STI Viral Hepatitis (free registration required for HCPs) (3 hours)
e-Learning for Health NHS http://www.e-lfh.org.uk/home/
85 Hepatitis B (chronic) diagnosis and management in children & adults (CG 165)
NICE NICE http://publications.nice.org.uk/hepatitis-b-chronic-cg165
362 Hepatitis Drug Interactions Website (Liverpool University)
Liverpool University http://www.hep-druginteractions.org/
60
Element 17 - STI, HIV AND OTHER BBV - CORE RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
363 SIGN 133: Management of Hepatitis C (July 2013) SIGN http://www.sign.ac.uk/guidelines/fulltext/133/index.html
424 UK consensus guidelines for the use of the protease inhibitors boceprevir and telaprevir in genotype 1 chronic hepatitis C infected patients (via TKN / Athens login)
Aliment Pharmacol Ther 2012; 35(6): 647-62
Ramachandran P et al
http://onlinelibrary.wiley.com.proxy.knowledgeservices.org/doi/10.1111/j.1365-2036.2012.04992.x/full
425 EASL Issue 8 (April 2012) Revised Clinical Practice Guidelines on the Management of Chronic Hepatitis B with corrigendum
Journal of Hepatology 2012 (57 ):167–185
EASL http://www.easl.eu/_clinical-practice-guideline/issue-8-april-2012-revised-clinical-practice-guidelines-on-the-management-of-chronic-hepatitis-b
HIV REFERENCES
69 HIV-STI 12 Specific Assessment and Management of HIV (free registration required for HCPs) (60 mins)
e-Learning for Health NHS http://www.e-lfh.org.uk/home/
361 HIV Drug Interactions Website (Liverpool University) Liverpool University http://www.hiv-druginteractions.org/
401 BHIVA and BIA Guidelines for the Treatment of Opportunistic Infection in HIV-seropostive individuals 2011
BHIVA http://www.bhiva.org/documents/Guidelines/OI/hiv_v12_is2_Iss2Press_Text.pdf
418 BHIVA guidelines summaries for patients BHIVA http://www.bhiva.org/guidelines-summaries.aspx
419 Introduction to combination therapy (good summary document for those new to subject)
iBase http://i-base.info/guides/starting
485 Impact of antiretroviral dosing frequency and pill burden on adherence among newly diagnosed, antiretroviral-naïve HIV patients (via TKN / Athens login)
Int J STD & AIDS 2012; 23: 351–355
Buscher A et al http://www.knowledge.scot.nhs.uk/
486 Adherence to Therapy, Treatment Success, and the Prevention of Resistance (via TKN / Athens login)
Infect Diseases in Clin Pract; 14(4):S15-18 2006
Jain SK et al http://www.knowledge.scot.nhs.uk/
487 Novel modular teaching of HIV patients and effect on adherence to HAART (via TKN / Athens login)
Tropical Med & Int Health 17(s1: 18
Busari O http://www.knowledge.scot.nhs.uk/
61
Element 17 - STI, HIV AND OTHER BBV - CORE RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
2012
SUPPLEMENTARY RESOURCESElement 17 - STI, HIV AND OTHER BBV - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
GENERAL STI/BBV/HIV REFERENCES
93 NES Sexual and Reproductive Health NES www.portal.scot.nhs.uk
128 Sexual Health in General Practice (Free Registration for HCPs) (2 hours)
RCGP http://elearning.rcgp.org.uk/course/view.php?search=infection&morelesson=1&id=33
410 UK National Guideline on the Management of Sexually Transmitted Infections and Related Conditions in Children and Young People 2010
BASSH http://www.bashh.org/documents/2674.pdf
420 Clinical Care Options Website (free registration for HCPs)
Clinical Care Options (CCO)
http://www.clinicaloptions.com/
STI REFERENCES
46 Neisseria gonorrhea – the first untreatable infection BSAC Prof Catherine Ison
http://bsac.org.uk/events/past-events-2013/bsac-spring-meeting-2013/bsac-spring-meeting-agm-2013-videos/
67 HIV-STI HPV Infection (free registration required for HCPs) 3 hours)
e-Learning for Health NHS http://www.e-lfh.org.uk/home/
247 Genital Herpes in Pregnancy, Management (Green-top 30) 2007
RCOG http://www.rcog.org.uk/womens-health/clinical-guidance/management-genital-herpes-pregnancy-green-top-30
62
Element 17 - STI, HIV AND OTHER BBV - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
249 BASHH Clinical Effectiveness Group Guidelines (have referred to specific guidelines elsewhere)
BASSH http://www.bashh.org/BASHH/Guidelines/Guidelines/BASHH/Guidelines/Guidelines.aspx
BBV REFERENCES
76 Hepatitis B - Tenofovir disoproxil TA173 NICE NICE http://publications.nice.org.uk/tenofovir-disoproxil-for-the-treatment-of-chronic-hepatitis-b-ta173
80 Hepatitis C (genotype 1) - Telaprevir TA252 NICE NICE http://publications.nice.org.uk/telaprevir-for-the-treatment-of-genotype-1-chronic-hepatitis-c-ta252
81 Hepatitis C (genotype 1) - Boceprevir TA253 NICE NICE http://publications.nice.org.uk/boceprevir-for-the-treatment-of-genotype-1-chronic-hepatitis-c-ta253
86 Hepatitis C (Children and Young People) Peginterferon Alfa & Ribavirin TA300
NICE NICE http://publications.nice.org.uk/peginterferon-alfa-and-ribavirin-for-treating-chronic-hepatitis-c-in-children-and-young-people-ta300
152 Diagnosis, Management and Treatment of Hepatitis C (AASLD)
HEPATOLOGY ; 2011 ; 54 : 1433 -1444
Ghany MG et al http://www.idsociety.org/Organism/
423 European Association for the Study of Liver EASL www.easl.eu
484 Interferon: an important step forward in treating hepatitis C infection (Registration required with RPS - fee)
The Pharmaceutical Journal2008;280:753
Bryan J http://www.pjonline.com/
481 Sequential treatment of cytomegalovirus infection or disease with a short course of intravenous ganciclovir followed by oral valganciclovir: efficacy. safety, and pharmacokinetics (via TKN - Athens login)
Transpl Infect Dis 2010: 12: 204-212
Caldes A et al http://www.knowledge.scot.nhs.uk/
HIV REFERENCES
252 BHIVA Guidelines (have referred to specific guidelines elsewhere)
BHIVA http://www.bhiva.org/ClinicalGuidelines.aspx
250 HIV infection pathology and disease progression Clinical Pharmacist Weston R et al http://www.pjonline.com/search/all?
63
Element 17 - STI, HIV AND OTHER BBV - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
(registration with RPS required - fee) 2009;1: 387 filter0=hiv+infection+pathology+and+disease+progression&filter8=weston&filter7%5BClinical+Pharmacist%5D=Clinical+Pharmacist&filter4=&filter5=&filter6=&filter3%5Bcpd_article%5D=cpd_article&filter2=**ALL**&filter1=**ALL**&
254 Cryptosporidiosis and its treatment CDC http://www.cdc.gov/parasites/crypto/health_professionals/tx.html
415 Treating opportunistic infections in HIV-infected children
CHIVA http://www.chiva.org.uk/professionals/health/guidelines/complications/treating-oi.html
416 Guidelines for the management of HIV infection in pregnant women 2012
BHIVA http://www.bhiva.org/PregnantWomen2012.aspx
181 Guidelines for the Prevention and Treatment of Opportunistic Infections Among HIV-Exposed and HIV-Infected Children
The Pediatric Infectious Disease Journal November 6, 2013
Siberry GK et al http://www.idsociety.org/Organism/
421 HIV pharmacists association (free registration required for pharmacists)
HIV PA hivpa.org
422 Guidelines for the Management of Hepatitis Viruses in Adults Infected with HIV 2013
BHIVA http://www.bhiva.org/hepatitis-2013.aspx
483 The Role of Therapeutic Drug Monitoring in the Management of Patients With Human Immunodeficiency Virus Infection (via TKN / Athens login)
Therapeutic Drug Monitoring. 33 (3):265-74 2011
Pretorius E et al http://www.knowledge.scot.nhs.uk/
426 Toronto General Hospital Immunodeficiency Clinic Drug Information/Interactions
Toronto General Hospital
http://hivclinic.ca/main/drugs_home.html
488 Pharmacists: Partners in Health Care for HIV-Infected Patients
NY State DoH AIDS Institute 2000-2013
http://www.hivguidelines.org/clinical-guidelines/hiv-and-pharmacy/pharmacists-partners-in-health-care-for-hiv-infected-patients/
64
Element 17 - STI, HIV AND OTHER BBV - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
302 ABC of HIV and AIDS 6th Ed 2012 if available (comes highly recommended but would need to be purchased)
BMJ Books Wiley Blackwell
Alder MW
65
Resources for Element 18 Tropical infectious diseasesCORE RESOURCES
Element 18 - TROPICAL INFECTIOUS DISEASES - CORE RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
GENERAL TROPICAL DISEASES REFERENCES
340 Travax (Free registration required for HCPs or possibly access via The Knowledge Network)
Health Protection Scotland
http://www.travax.nhs.uk/
MALARIA REFERENCES
469 Guidelines for malaria prevention in travelers from the United Kingdom 2013
Public Health England Chiodini PL et al http://www.hpa.org.uk/webw/HPAweb&HPAwebStandard/HPAweb_C/1195733823080?p=1191942128258
243 Malaria in pregnancy prevention (Green-top 54A) 2010 RCOG http://www.rcog.org.uk/prevention-malaria-pregnancy-green-top-54a
244 Malaria in pregnancy diagnosis & treatment (Green-top 54B) 2010
RCOG http://www.rcog.org.uk/diagnosis-and-treatment-malaria-pregnancy-green-top-54b
349 The British Infection Society UK Malaria Treatment Guidelines (2007)
Journal of Infection (2007); 54: 111-121
Laloo DG et al http://www.britishinfection.org/drupal/sites/default/files/malariatreatmentBIS07.pdf
351 The British Infection Society Malaria Algorithm for Diagnosis & Initial Management
BIS http://www.britishinfection.org/drupal/sites/default/files/MalariaAlgorithm07.pdf
OTHER TROPICAL DISEASES REFERENCES
255 Diagnosis and treatment of amebiasis Clin Infect Dis 1999;29:1117-25
Petri WA http://cid.oxfordjournals.org/content/29/5/1117.full
257 Review: Diagnosis and Management of Schistosomiasis (via TKN / Athens login)
BMJ2011;342:d2651 Gray DJ et al http://www.bmj.com/content/342/bmj.d2651
427 Rabies: Guidance on Prophylaxis and Management in Humans in Scotland
Health Protection Scotland
http://www.documents.hps.scot.nhs.uk/about-hps/hpn/rabies-guidelines-2013.pdf
428 Leishmaniasis Clin Med 2011; 11(5): Moore EM, http://www.clinmed.rcpjournal.org/content/
66
Element 18 - TROPICAL INFECTIOUS DISEASES - CORE RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
492-7 Lockwood DN 11/5/492.full.pdf
355 WHO Ebola, Marburg and Crimean Congo Haemorrhagic Fever Factsheets
WHO http://www.who.int/mediacentre/factsheets/en/
222 The evolving threat of antimicrobial resistance WHO http://whqlibdoc.who.int/publications/2012/9789241503181_eng.pdf
SUPPLEMENTARY RESOURCES Element 18 - TROPICAL INFECTIOUS DISEASES - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
GENERAL TROPICAL DISEASE REFERENCES
342 National Travel Health Network and Centre NaTHNaC http://www.nathnac.org/pro/index.htm
343 CDC Health Information for International Travel (Yellow Book)
CDC http://wwwnc.cdc.gov/travel/page/yellowbook-home-2012
345 Travel Health (60 mins) NES http://www.nes.scot.nhs.uk/media/1912665/travel_health_interactive.pdf
379 Immunisation against infectious disease: the green book
DoH https://www.gov.uk/government/organisations/public-health-england/series/immunisation-against-infectious-disease-the-green-book
429 Hunter's Tropical Medicine and Emerging Infectious Disease: Expert Consult -2013 Online and Print, 9e if available
Elsevier Magill AJ et al (ED)
430 Manson's Tropical Diseases 23rd Edition 2013 if available
Elsevier Farrar J et al (Ed)
MALARIA REFERENCES
67
Element 18 - TROPICAL INFECTIOUS DISEASES - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
348 The London Hospital of Tropical Medicine Malaria Guidelines 2013
The Hospital for Tropical Diseases
http://www.thehtd.org/Malaria%20guideline_final_June2013.pdf
350 The British Infection Society New Guidelines on Malaria Prevention: A Summary
Journal of Infection (2007); 54: 107-110
Swales CA et al http://www.britishinfection.org/drupal/sites/default/files/malariapreventionBIS07.pdf
OTHER TROPICAL DISEASES REFERENCES
354 WHO Expert Consultation on Rabies 2013 WHO http://apps.who.int/iris/bitstream/10665/85346/1/9789240690943_eng.pdf
68
Resources for Element 19 Chronic respiratory tract infections - tuberculosis (TB), cystic fibrosis (CF) and non-CF bronchiectasis CORE RESOURCES
Element 19 - CHRONIC RESPIRATORY INFECTION - TB, CF & BRONCHIECTASIS - CORE RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
TUBERCULOSIS REFERENCES
70 Tuberculosis NICE CG 117 NICE NICE http://publications.nice.org.uk/tuberculosis-cg117
197 Guidelines for the prevention and management of Mycobacterium tuberculosis infection and disease in adult patients with chronic kidney disease
Thorax 2010;65:559e570
Milburn H et al http://www.brit-thoracic.org.uk/guidelines-and-quality-standards/tuberculosis-guideline/
258 Extensively drug-resistant tuberculosis (via TKN / Athens login)
Lancet Infect Dis 2009;9: 19-30
Jassal M http://www.ncbi.nlm.nih.gov/pubmed/18990610
298 WHO Guidelines for the programmatic management of drug-resistant tuberculosis 2011
WHO http://whqlibdoc.who.int/publications/2011/9789241501583_eng.pdf
CYSTIC FIBROSIS REFERENCES
464 Antibiotic Treatment for Cystic Fybrosis – 3rd Edition Report of the UK Cystic Fibrosis Trust Antibiotic Working Group
Cystic Fibrosis Trust http://cysticfibrosis.org.uk/media/82010/antibiotic-treatment-for-cystic-fibrosis-may-09.pdf
95 Cystic fibrosis (pseudomonas lung infection) - colistimethate sodium and tobramycin TA276 (2013)
NICE NICE http://publications.nice.org.uk/colistimethate-sodium-and-tobramycin-dry-powders-for-inhalation-for-treating-pseudomonas-lung-ta276
501 Oxford Textbook of Medicine 2003 see chapter on cystic fibrosis (via TKN)
Oxford University Press
Warrell D www. knowledge .scot.nhs.uk/
NON-CF BRONCHIECTASIS REFERENCES
192 The BTS Guideline for non-CF Bronchiectasis Thorax (Volume 65, Supplement 1) 2010
Pasteur MC et al http://www.brit-thoracic.org.uk/guidelines-and-quality-standards/bronchiectasis-guideline/
69
SUPPLEMENTARY RESOURCESElement 19 - CHRONIC RESPIRATORY INFECTION - TB, CF & BRONCHIECTASIS - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
TUBERCULOSIS REFERENCES
169 Diagnosis, Treatment and Prevention of Nontuberculous Mycobacterial Diseases
Am J Resp Crit care Med 2007 ; 175 : 367 -416
Griffith DE et al http://www.idsociety.org/Organism/
199 Management of opportunist mycobacterial infections: Joint Tuberculosis Committee guidelines 1999
Thorax 2000;55:210–218
Campbell IA et al http://www.brit-thoracic.org.uk/guidelines-and-quality-standards/non-tuberculous-mycobacteria/
297 WHO Treatment of tuberculosis: guidelines for national programmes 4th Ed 2009
WHO http://www.who.int/tb/publications/tb_treatmentguidelines/en/index.html
317 Tuberculosis Clinical Vignette (10)( free registration required for HCPs) Good if limited access to patients with TB (3 hours)
PAUSE BSAC http://www.pause-online.org.uk
323 Tuberculosis Clinical Vignette (16)(free registration required for HCPs) ) Good if limited access to patients with TB (2 hours)
PAUSE BSAC http://www.pause-online.org.uk
454 British Infection Society guidelines for the diagnosis and treatment of tuberculosis of the central nervous system in adults and children
Journal of Infection (2009) 59, 167-187
Thwaites G et al http://www.britishinfection.org/drupal/sites/default/files/CNS%20TB%202009%20Thwaites.pdf
CYSTIC FIBROSIS REFERENCES
445 Cystic Fibrosis & OPAT - What can we learn? BSAC Iara-Mina Sequeios
http://e-opat.com/downloads
463 Antibiotic Prescribing Guidelines in Adults with Cystic Fibrosis - 2013 V2 Example of local adaptation of Cystic Fibrosis Trust Guidance
NHS Lothian McCabe D et al Awaiting link to NES website
461 Standards of care for patients with cystic fibrosis: a Journal of cystic Barreto C et al http://www.sciencedirect.com/science/article/pii/
70
Element 19 - CHRONIC RESPIRATORY INFECTION - TB, CF & BRONCHIECTASIS - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
European consensus fibrosis 2005; 4: 7 – 26
S1569199304002139
462 Cystic Fibrosis Foundation evidence-based guidelines for management of infants with cystic fibrosis.
J Pediatr. 2009 Dec;155(6 Suppl):S73-93.
Borowitz D et al http://www.guideline.gov/content.aspx?f=rss&id=43789
500 Cystic Fibrosis Pharmacological Management (registration required with RPS - fee)
Clinical Pharmacist 2011;3:245
Smyth S http://www.pjonline.com/
499 Cystic Fibrosis Physiology and Diagnosis (registration required with RPS - fee)
Clinical Pharmacist 2011;3: 239
Cuevas OA http://www.pjonline.com/
514 Influence of multiple courses of therapy on aminoglycoside clearance in adult patients with cystic fibrosis
J. Antimicrob. Chemother. (2013) 68 (6): 1338-1347
Alghanem S et al http://jac.oxfordjournals.org/content/68/6/1338.full.pdf+html?hwoaspck=true
515 Population pharmacokinetics of tobramycin in patients with and without cystic fibrosis (via TKN/Athens login)
Clinical Pharmacokinetics 2013 52 (4): 289-301
Hennig S et al www.knowledge.scot.nhs.uk/
516 Pharmacokinetic and pharmacodynamic optimisation of intravenous tobramycin dosing among children with cystic fibrosis (via TKN/Athens login).
J pharmacokinet pharmacodynam 2014;41(1): 71-79
Sherwin CMT et al
www.knowledge.scot.nhs.uk/
517 Once versus three-times daily regimens of tobramycin treatment for pulmonary exacerbations of cystic fibrosis--the TOPIC study: a randomised controlled trial (via TKN/Athens login)
Lancet. 2005;365(9459):573-8
Smyth A et al www.knowledge.scot.nhs.uk/
71
Resources for Element 20 Fungal infectionsCORE RESOURCES
Element 20 - FUNGAL INFECTION - CORE RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
GENERAL FUNGAL AND ANTIFUNGAL REFERENCES
Available textbook(s) for background information
367 Fungal Skin and Nail Infections Primary Care Quick Reference Guide
HPA http://www.hpa.org.uk/webc/HPAwebFile/HPAweb_C/1240294785726
431 NICE CKS Guidelines on Fungal nail & skin infections NICE NICE CKS http://cks.nice.org.uk/
432 Guidelines on the management of invasive fungal infection during therapy for haematological malignancy
British Committee on Standards in Haematology
Prentice AG et al http://www.bcshguidelines.com/documents/fungal_infection_bcsh_2008.pdf
171 Treatment of Aspergillosis Clin Infect Dis 2008 ; 46 : 327 -360
Walsh TJ et al http://www.idsociety.org/Organism/
174 Practice Guidelines for the Management of Cryptococcal Disease
Clin Infect Dis 2010 ; 50 : 291 -322
Perfect JR http://www.idsociety.org/Organism/
175 Guidelines for The Management of Candidiasis Clin Infect Dis 2009 ; 42 : 503 -535
Pappas PG http://www.idsociety.org/Organism/
Local guidelines for e.g. management of Pneumocystic jirovecii
THERAPEUTIC DRUG MONITORING REFERENCES
503 Therapeutic drug monitoring (TDM) of antifungal agents: guidelines from the British Society for Medical Mycology
J Antimicrob Chemother (2013) doi: 10.1093/jac/dkt508
Ashbee HR et al http://jac.oxfordjournals.org/content/early/2013/12/28/jac.dkt508.full?hwoaspck=true&sid=94fb36c1-9153-44c8-b5a5-bddaddddb708
72
SUPPLEMENTARY RESOURCESElement 20 - FUNGAL INFECTION - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
GENERAL FUNGAL AND ANTIFUNGAL REFERENCES
50 Directed therapy for fungal infections – latest advances (30 mins)
BSAC Dr Rosemary Barnes
http://bsac.org.uk/events/past-events-2013/bsac-spring-meeting-2013/bsac-spring-meeting-agm-2013-videos/
465 An Official American Thoracic Society Statement: Treatment of Fungal Infections in Adult Pulmonary and Critical Care Patients (also covers Pneumocystic jirovecii)
Am J Respir Crit Care Med 2011; 183: 96–128
Limper AH et al http://www.thoracic.org/statements/resources/tb-opi/treatment-of-fungal-infections-in-adult-pulmonary-critical-care-and-sleep-medicine.pdf
172 Clinical Practice Guidelines for the Management of Blastomycosis
Clin Infect Dis 2008 ; 46 : 1801 -1812
Chapman SW http://www.idsociety.org/Organism/
173 Practice Guidelines for the Treatment of Coccidioidomycosis
Clin Infect Dis 2005 ; 41 : 1217 -1223
Galgiani JN http://www.idsociety.org/Organism/
176 Clinical Practice Guidelines for the Management of Patients with Histoplasmosis: 2007 Update by the Infectious Diseases Society of America"
Clin Infect Dis 2007 ; 45 : 807 -825
Wheat LJ http://www.idsociety.org/Organism/
177 Clinical Practice Guidelines for the Management of Sporotrichosis: 2007 Update by the Infectious Diseases Society of America
Clin Infect Dis 2007 ; 45 : 1255 -1265
Kauffman CA http://www.idsociety.org/Organism/
THERAPEUTIC DRUG MONITORING REFERENCES
480 Optimizing antifungal choice and administration (via TKN / Athens login)
Curr Med Research Opin. 29, Sup 4, 2013, 13–18
Andes D http://informahealthcare.com.proxy.knowledgeservices.org/doi/pdf/10.1185/03007995.2012.761135
73
Resources for Element 21 Outpatient parenteral antimicrobial therapy (OPAT)CORE RESOURCES
Element 21 - OPAT - CORE RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
GENERAL OPAT REFERENCES
190 Good practice recommendations for outpatient parenteral antimicrobial therapy (OPAT) in adults in the UK: a consensus statement
JAC (2012) 67 (5): 1053-1062.
Chapman ALN et al
http://jac.oxfordjournals.org/content/67/5/1053.full
268 Pharmaceutical Care in OPAT (via TKN) (15 mins) ASAP Shared Space Robb F http://www.elib.scot.nhs.uk/SharedSpace/pharmacy/Pages/RecordDetailFull.aspx?nid=229082&ret=http%3a%2f%2fwww.elib.scot.nhs.uk%2fSharedSpace%2fpharmacy%2fPages%2fRecordDetailShort.aspx%3fnid%3d229082%26ret%3d%2fSharedSpace%2fpharmacy%2fPages%2fIndex.aspx%3
328 Outpatient Parenteral Antibiotic Therapy (OPAT) Clinical Vignette (21) (free registration for HCPs) (3 hours)
PAUSE BSAC http://www.pause-online.org.uk
504 eOPAT website BSAC BSAC http://e-opat.com/
56 Microbiology - present and future (20 mins) BSAC Nick Brown http://e-opat.com/downloads/
SPECIFIC CONDITIONS OR DRUGS IN OPAT REFERENCES
55 Role of OPAT in DFI - benefits, drugs, issues (10 mins) BSAC Paul Chadwick/Claire McIntosh
http://e-opat.com/downloads/
433 Treating infections in Bone & Joint in acute and OPAT settings
NES Andrew Seaton To be uploaded once recorded
434 Treating infections in Skin & Soft Tissue in acute and OPAT settings (60 mins)
NES Andrew Seaton http://vimeo.com/79984822 for video
and
74
Element 21 - OPAT - CORE RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
http://www.nes.scot.nhs.uk/education-and-training/by-discipline/pharmacy/about-nes-pharmacy/educational-resources/resources-by-topic/infectious-diseases/antibiotics/treating-infection-in-skin,-soft-tissue,-bone-and-joints-for-asap.aspxfor handout
189 Development of teicoplanin dosage guidelines for patients treated within an (OPAT) programme
JAC (2009) 64 (1): 181-187.
Lamont E et al http://jac.oxfordjournals.org/content/64/1/181.full
SUPPLEMENTARY RESOURCESElement 21 - OPAT - SUPPLEMENTARY RESOURCES
Resource ID Name of resource Resource owner
Presenter/Author URL link direct to resource
Date Resource Accessed/ Comments
GENERAL OPAT REFERENCES
142Practice Guidelines for Outpatient Parenteral Antimicrobial Therapy
Clin Infect Dis ; 2004 ; 38 : 1651 -1672
Tice AD et al http://www.idsociety.org/Antimicrobial_Agents/#Outpatient Parenteral Anti-Infective Therapy (OPAT)
444 What are the ideal OPAT agents? (20 mins) BSAC DR Robin Howe http://e-opat.com/downloads
SPECIFIC CONDITIONS OR DRUGS IN OPAT REFERENCES
445 Cystic Fibrosis & OPAT - What can we learn? BSAC Iara-Mina Sequeios
http://e-opat.com/downloads
505 Risk factors for failure of outpatient parenteral antibiotic therapy (OPAT) in infective endocarditis
J Antimicrob Chemother (2013) 68 (7): 1650-1654.
Duncan CJA et al http://jac.oxfordjournals.org/content/68/7/1650
75
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