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StatXact® 11 provides statisticians in disciplines across the social and natural sciences with the world’s most expansive toolkit for exact inference and power analysis. Offering more than 150 tests and procedures, the StatXact® suite has transformed the complex algorithms of modern statistical analysis into a validated software package with a user-friendly interface. New in Version 11 Improved tests for 2x2 tables: Blaker’s Method for p-values and confidence intervals Bayesian procedures for 2x2 tables: compare proportions using the risk difference, risk ratio and odds ratio Increased flexibility through R language: customized tests using R functions New correlation structures for categorical data: adjacent and equal correlation coefficient options when testing two ordered multinomials, unordered RxC tables, singly ordered RxC tables and doubly ordered RxC tables Only in StatXact Exact tests for equivalence and non-inferiority of paired and independent binomial data Exact tests on unordered, singly ordered and doubly ordered RxC tables, with Cochran-Mantel-Haenszel (CMH) tests, for correlated data Exact tests of trend in C correlated binomial populations Exact tests for correlated two samples data: Wilcoxon Mann-Whitney, Normal scores, Savage scores, and Permutation Exact inference on one-sample Poisson rates and Homogeneity and CI on common relative risks and trend in C ordered rates for Poisson data Exact power and sample size calculations for binomial and multinomial tests StatXact® PROCs for SAS Users Did you know you can use Cytel‘s nonparametric and exact inference methods within SAS? StatXact® PROCs plugs into SAS, providing immediate access to: Over 150 additional tests and procedures — all fully referenced and validated More nonparametric inference exact statistics see back page Automation of batch jobs and documentation for submittals within SAS All within SAS. The Most Popular Software for Exact Inference Available in StatXact 10 and 11: Correlated data analysis: Exact tests for ordered and unordered multinomial data Genetics data analysis: Exact Family Based Association Tests Increased power for 2x2 tables: Boschloo’s test, power and sample size calculations Improved confidence intervals: Mid-p correction Detection of shift and dispersion in comparing two populations: Lepage Test Stratified data analysis of two independent samples: Aligned Mid-rank Score Test

New in Version 11 Only in StatXact All within SAS ...for SAS Users Did you know you can use Cytel‘s nonparametric and exact inference methods within SAS? StatXact® PROCs plugs into

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Page 1: New in Version 11 Only in StatXact All within SAS ...for SAS Users Did you know you can use Cytel‘s nonparametric and exact inference methods within SAS? StatXact® PROCs plugs into

StatXact® 11 provides statisticians in disciplines across the social and natural sciences with the world’s most expansive toolkit for exact inference and power analysis. O�ering more than 150 tests and procedures, the StatXact® suite has transformed the complex algorithms of modern statistical analysis into a validated software package with a user-friendly interface.

New in Version 11• Improved tests for 2x2 tables: Blaker’s Method for p-values and con�dence intervals

• Bayesian procedures for 2x2 tables: compare proportions using the risk di�erence, risk ratio and odds ratio

• Increased �exibility through R language: customized tests using R functions

• New correlation structures for categorical data: adjacent and equal correlation coe�cient options when testing two ordered multinomials, unordered RxC tables, singly ordered RxC tables and doubly ordered RxC tables

Only in StatXact • Exact tests for equivalence and non-inferiority of paired and independent binomial data

• Exact tests on unordered, singly ordered and doubly ordered RxC tables, with Cochran-Mantel-Haenszel (CMH) tests, for correlated data

• Exact tests of trend in C correlated binomial populations

• Exact tests for correlated two samples data: Wilcoxon Mann-Whitney, Normal scores, Savage scores, and Permutation

• Exact inference on one-sample Poisson rates and Homogeneity and CI on common relative risks and trend in C ordered rates for Poisson data

• Exact power and sample size calculations for binomial and multinomial tests

StatXact® PROCs for SAS Users

Did you know you can use Cytel‘s nonparametric and exact inference methods

within SAS? StatXact® PROCs plugs into SAS, providing immediate

access to:

• Over 150 additional tests and procedures — all fully referenced and validated

• More nonparametric inference exact statistics — see back page —

• Automation of batch jobs and documentation for submittals within SAS

All within SAS.

The Most Popular Software for Exact Inference

Available in StatXact 10 and 11: • Correlated data analysis: Exact tests for ordered and unordered multinomial data

• Genetics data analysis: Exact Family Based Association Tests

• Increased power for 2x2 tables: Boschloo’s test, power and sample size calculations

• Improved con�dence intervals: Mid-p correction

• Detection of shift and dispersion in comparing two populations: Lepage Test

• Stratified data analysis of two independent samples: Aligned Mid-rank Score Test

Page 2: New in Version 11 Only in StatXact All within SAS ...for SAS Users Did you know you can use Cytel‘s nonparametric and exact inference methods within SAS? StatXact® PROCs plugs into

StatXact SAS

One-sample Goodness-of-Fit

SEYES YESerauqS-ihC

SEYvorogomloK

SEYsrofeilliL

SEYsnuR

Paired Samples

SEYES YESngiS

Wilcoxon Signed-Rank YES YES

Hodges Lehman Estimates YES

SEYnoitatumreP

McNemar - Conditional YES YES

McNemar - Unconditional Yes

Marginal Homogeneity YES

Two Independent Samples

Wilcoxon-Mann-Whitney YES YES

Hodges Lehman estimates YES

Normal Scores YES YES

Savage Scores YES YES

Lepage YES

Aligned Midrank Score (strati�ed) YES

SEYES YESyekuT-legeiS

Ansari-Bradley YES YES

SEYES YESztolK

SEYES YESdooM

SEYrevonoC

Permutation YES YES

SEYknargoL

Wilcoxon-Gehan YES

Kolmogorov-Smirnov YES YES

Wald-Wolfowitz Runs YES

K Related Samples

SEYnamdeirF

SEYW s'lladneK

SEYQ s'narhcoC

SEYedauQ

SEYegaP

K Independent Samples

SEYES YESnaideM

Kruskall-Wallis YES YES

Normal Scores YES YES

SEYES YESegavaS

ANOVA with General Scores YES YES

Jonckheere-Terpstra YES YES

Linear by Linear YES YES

SEYknargoL

Wilcoxon-Gehan YES

Tarone and Ware Trend YES

StatXact SAS

One-Sample Rates and Proportions

SEYSEYlaimoniB

SEYlaimonitluM

SEYnossioP

Poisson Rates

Homogeneity of Relative Risks YES

CI on Common Relative Risk YES

Trend in C Ordered Poisson Rates YES

Two Independent Binomials

Fisher's Exact YES YES

Boschloo YES

Pearson's Chi-square YES YES

Likelihood Ratio YES YES

CI on Odds Ratio YES YES

Barnard's Test for Superiority YES YES

Tests of Non-inferiority YES

Tests of Equivalence YES

CI on Di�erence of Proportions YES YES

CI on Ratio of Proportions YES YES

Two Related Binomials

SEYES YESrameNcM

CI on odds Ratio YES

Test for Superiority YES

Tests of Non-inferiority YES

Tests of Equivalence YES

CI on Di�erence of Proportions YES

Strati�ed 2x2 Tables

Homogeneity of Odds Ratios YES YES

CI on Common Odds Ratios YES YES

C Ordered Binomials

Correlated and Uncorrelated

Cochran-Armitage Trend YES

Permutation with General Scores YES

Trend Test for Clustered Data YES

Test for Interaction Across Strata YES

Two Ordered Multinomials

Wilcoxon-Mann-Whitney YES

Savage Scores YES

Normal Scores YES

Permutation with General Scores YES

Test for Interaction Across Strata YES

Unordered RxC Table

Pearson's ChiSquare YES

Likelihood Ratio YES

Fisher-Freeman-Halton YES

StatXact SAS

Single Ordered RxC Table

Kruskal-Wallis YES

Normal Scores YES

SEYESegavaS

ANOVA with Arbitrary Scores YES

Doubly Ordered RxC Table

Jonckheere-Terpstra YES

Linear by Linear Association YES

Strati�ed RxC Tables

Unordered RxC Table YES

Single Ordered RxC Table YES

Doubly Ordered RxC Table YES

Measures of Association (nominal)

Contingency Coe�cients YES

Goodman-Kruskal-Tau YES

Uncertainty Coe�cient YES

Measures of Association (ordinal)

Pearson's Correlation YES YES

Spearman's Correlation YES YES

Kendall's Concordance YES

Kendall's Tau and Somers' D YES YES

Gamma Coe�cient YES

Measures of Agreement

Cohen's Kappa YES YES

Weighted Kappa YES YES

Power & Sample Size

One Binomial YES YES

Genetic Data

Family Based Association Test YES YES

Paired Binomials: Di�erence YES

Two Binomials: Di�erence

YES

YES

K ordered Binomials YES

Two Ordered Multinomials (power) YES

Bayesian Inference

Two Binomials: Ratio

Superiority, Non-inferiority, Equivalence

Superiority, Non-inferiority, Equivalence

YES

YES

StatXact 11 compared to SASThe most non-parametric and exact methods.Now with R integration and expanded OS support.

www.cytel.com 675 Massachusetts Ave., Cambridge, MA 02139 +1.617.661.2011

Available for correlated and uncorrelated data with or without strata

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