National Seminar on“ Potential of tribal medicine to treat ... s/Archive-2017... · National Seminar on“ Potential of tribal medicine to treat life threatening diseases” on

National Seminar on“ Potential of tribal medicine to treat life

threatening diseases” on 1st Nov. 2017

Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-

7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]

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SOUVENIR

National Seminar

On

“ POTENTIAL OF TRIBAL MEDICINE TO TREAT LIFE THREATENING DISEASES”

1ST November 2017

(Wednesday)





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Organizing Committee

Mrs. Alka Dubey

Patron

Mr. Amresh Dubey

Patron

Convener

Dr. P. K. Dubey

Director

Swami Vivekanand Group of Institutions

Organizing Secretary

Mr. Satyaendra K. Shrivastava

Dean (Academics & Administration)

Swami Vivekanand College of Pharmacy

Coordinators

Dr. (Mrs.) Shikha Agrawal

Vice-Principal

Swami Vivekanand College of Pharmacy





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Chairpersons of the committee

Registration

Committee

Dr. Priya Jain, Mrs. Steffy Mary Chandy,

Mrs. Pooja Pancholi, Mrs. Jyoti Jayaswal,

Mr. Praveen Sharma

Technical & Scientific

Committee

Mr. Dishant Gupta, Mrs. Archana Tiwari,

Mrs. Darshana Sharma, Mrs. Priya Jain, Mr.

Dilip Prajapati

Inauguration

Committee

Ms. Pooja Tiwari, Mrs. Priyanka Pandey,

Mrs. Khushboo Naik, Ms. Ankita Mane

Hospitality and

Transportation

Committee

Mr. Rupesh Pandey, Mr. Satyendra Yadav,

Mr. Sachin Okhade, Mr. Poonam S. Rajput





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Editorial Board

Dr. P. K. Dubey Director

Dr. (Mrs.) Shikha Agrawal Vice-Principal

Mr. Satyendra K. Shrivastava Dean (Acad. & Admin.)

Dr. Priya Jain HOD (Ph. Chemistry)

Mr. Dishant Gupta HOD (Pharmacognosy)

Mr. Rupesh Pandey HOD (Pharmacology)





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Programme schedule

On 01/11/2017

Time Schedule Programmed Details

Concurrent Sessions

09:00am-10:00am Registration & Breakfast

10:00am-11:00am Inauguration

11:00am-12:00pm Plenary Lecture I

12:00pm- 01:00pm Scientific Session

Lunch

02:00pm-03:00pm Scientific Session

03:00pm-04:00pm Valedictory Function





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Abstract index

ABSTRACT NO.

TITLE NAME OF

PRESENTING

AUTHOR

PAGE NO.

PH/2017/01 Physicochemical Investigation of Vidanga

Berries

Sweta.V.Kulkarni 15

PH/2017/02 A Review on Recent Microbial Diseases:

Information on a Fatal Battle

Danish Pariyani 16

PH/2017/03 Synthesis and Evaluation of azetidin

derivatives as antimicrobial activity

M.C. Sharma 17

PH/2017/04 Traditional Phytotherapy among tribal and

local villages of Madhya Pradesh, India used

in the treatment of Gynecological Disorders

Shweta Shriwas 18

PH/2017/05 Application of liquisolid technique to enhance

solubility and dissolution profile of poorly

water soluble drugs

Madhavi Kasturi 19

PH/2017/06 Polymeric Microparticles containing herbal

plant extracts for managemet of diabetes

Neelima Salvi 20

PH/2017/07 Theraputic Profile of Mucunapruriense linn

Priyanka Singh 21

PH/2017/08 WHO Guidelines for Herbals

Deepanshi

Saklecha

22

PH/2017/09

Study of effect of Curcuma Zeodaria

roscoe. on oxidative-stress animal model

Elangovan

Manivannan

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PH/2017/10 Herbal Hand sanitizer: Need for today

Virendra S

Rathore

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PH/2017/11 Quality Control Parameters For Herbal

Drugs and Formulations

Twinkle Copuhan 25

PH/2017/12 Virtual Screening of Phyto-constituents as

anticancer agents

Nidhi Gupta 26

PH/2017/13 Tribal medicines used in treatment of

psoriasis

Gaurav patidar 27

PH/2017/14 A Review On Ethnomedicine Of Bhil Tribe

Of Jhabua District

Ayush Soni 28

PH/2017/15 A Review on Medicinal Plants used by the

Tribal People of Satna District, M.P.

Kundan Patidar 29

PH/2017/16 Traditional tribal medicines Aloe-vera used

as a anticancer drug

Manoj Gour 30

PH/2017/17 Tribal medicines in mosquito borne diseases

Nafia Rahman 31

PH/2017/18 Hypoxis in the treatment of hiv/aids

Harshita Sharma 32

PH/2017/19 A review on Swine Flu treatment by tribal

medicines using Tinospora Cordifolia

Akshat S Baghel 33

PH/2017/20 A Review On Tribal Medicine The Untapped

Treasure

Varsha Gadekar 34

PH/2017/21 A Review on Potential and Traditional Use

of Dioscorea Species (A Wild Edible Tuber)

by the Local People of Similipal Biosphere

Reserve, India

Chetna Mandloi 35

PH/2017/22 Tribal medicine Practices in North East

India

Deepak paudel 36

PH/2017/23

Linum usitatissimum used in Tribal

medicine

Khushali Pinge 37





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PH/2017/24 Tribal medicine to treat Schizophrenia

Vrishti Thakur 38

PH/2017/25 Treatment of musculoskeletal diseases by

bonesetter shrub

Harsh Pendharkar 39

PH/2017/26 Tribal medicine to treat hepatitis B

Priya Gawla 40

PH/2017/27 Drumstick tree used as tribal medicine

Nikhil Gupta 41

PH/2017/28 Investigation of analgesic activity of

polyherbal preparation (Topical Gel)

containing herbal extract

Suman Gehlot 42

PH/2017/29 Formulation and Evaluation of herbal oil for

the treatment of arthritis

Sumeet Dwivedi 43

PH/2017/30 Pharmacognostical, Physicochemical and

Chromatographic Evaluation of Polyherbal

Formulation: Navasaya Churna

Nirmal Dongre 44

PH/2017/31 Formulation and evaluation of new nasal

drop using Essential Oil of Black Mustard

(Brassica nigra) for the Management of

Bacterial Rhinosinusitis

Harshit Sharma 45

PH/2017/32 Evaluation of Anti-diabetic activity of

Poly Herbal Antidiabetic Tablet Glucomap

Satyaendra K.

Shrivastava

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PH/2017/33 Tribal medicine’- Antidote to snake venom

Zainab

Pandhanawala

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Physicochemical Investigation of Vidanga Berries

Sweta V. Kulkarni*, Arun K. Gupta and Raju Choukse

School of Pharmacy, Dr.A.P.J.Abdul Kalam University, Indore, M.P

Abstract

Herbal medicines are being used as a effective source for treatment of

many diseases since ancient times. Embelin, is an active phytoconstituent

obtained from fruits of Embelia tsjeriam cottam, commonly known as

Vidanga. Vidanga consists of phytoconstituents which is used o cure

various severe diseases. Thus there is a need to justify the Quality of the

herbal drugs which are highly used nowadays. Standardization methods

hence act as an tests performed to ensure the safety of health. Also the

phytochemical investigation is performed to make the use of important

chemical constituents to its fullest. In this work we have performed

various evaluation tests as per Ayurvedic Pharmacopia which were found

to be within the limits. An effort was made further to optimize the best

extraction solvent. UV spectroscopic scanning was done from 200-400nm

of which λmax was found to be 291nm with a good peak shape and height

for chloroform. HPTLC studies revealed a better peak height for

Toulene:ethyl acetate and better separation of constitutents at

chloroform:methanol for chloroform solvent. Thus Chloroform was found

to the best solvent for extraction of vidanga berries.

Keywords: Vidanga, Embelia tsjeriam cottam, Phytochemical,

Standardization

*Corresponding Author Sweta V. Kulkarni





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A Review on Recent Microbial Diseases: Information on a Fatal Battle

Danish Pariyani*, Vaibhav Sharma, Mili Satle, Jacky Dumbwani,

Sanjay Jain

Indore Institute of Pharmacy, Rau-Pithampur Road, Opp. IIM, Rau,

Indore-453331

Abstract

The whole world is facing a dangerous problem originated through variety

of microorganism. Infections can caused by microorganisms — such as

bacteria, viruses, fungi or parasites. Infectious disease is a significant

burden on the public health and economic stabilities of society all over the

world. It has become the leading cause of death and disability and

presented a challenge to health sector and human progress over some

decades. Over the last two, three decades many of the infectious disease

are identified like Hepatitis C, West Nile Virus, SARS, Chikungunya, Swine

Flu, MERS, Ebola, and Zika. Most of the diseases are zoonotic and there

origin has been due to environmental, socioeconomic factors. This review

presents the overview of the diseases, microorganism, drug and its

availability in the local area. Recently people are suffering from a panic

disease called chikungunya due lack of information patient are increasing

and are not getting proper treatment. This review also includes the

location of health centers and availability of drug in the city.

Key Words: Infectious Diseases, Public Health, Death, Environment,

Drug Availability

*Corresponding Author : Danish Pariyani





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Synthesis and Evaluation of azetidin derivatives as antimicrobial

activity

M.C. Sharma*

School of Pharmacy, Devi Ahilya University, Khandwa Road, Indore, MP

452 001, India

Abstract

Present communication deals with the synthesis of a novel series of

compounds embracing azetidin nucleus in their molecular architecture. The

compounds were synthesized in excellent yields and their structures were

corroborated on the basis of IR, NMR, Mass analyses data. Moreover, the

antimicrobial potential of synthesized compounds was tested against a

panel of fungi. It also emphasizes the domination of steric properties over

the volumetric properties for modeling the activity against specific type

of bacteria. All the synthesized compounds have been found to delineate

profound antimicrobial potency as compared to reference drug.

*Corresponding Author- M.C. Sharma





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Traditional phytotherapy among tribal and local villages of Madhya

Pradesh, India used in the treatment of Gynecological Disorders

Sumeet Dwivedi, Shweta Shriwas* and Raghvendra Dubey

College of Pharmacy, Dr. APJ Abdul Kalam University, Indore, (M.P.) -

India

Abstract

Madhya Pradesh, a Central State of India is rich in natural heritage due to

tribal impact. The wide diversity of natural resources of the state along

with the tribal population focuses in the use of herbs for the treatment

of various disease and disorders. Gynecological disorders viz., menstrual

disorders, vaginitis, uterine bleeding, vaginal inflammation, itching etc. are

now-a-days very common disorder almost in every woman. The tribe of the

region uses traditional herbs for the treatment of these disorders.

Available allopathic medicines are costly, have side effects and also due to

social custom, tribes of the region use herbs for the treatment of

gynecological disorders. The present paper enumerates fifty herbs viz.,,

Achyranthes aspera, Tachyspermum ammi, Plumeria pudica, Cissus

quandragularis, Nigella sativa, Ipomea mauritiana, etc. which are commonly

used to treat gynecological disorders. The local name, dose, duration,

disease condition treatment along with method of preparation has been

presented in present investigation.

Key-Words: Herbal remedies, Madhya Pradesh, Gynecological Disorders

*Corresponding Author: Shweta Shriwas

[email protected], [email protected]

Mob.+91-9893478497





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Application of liquisolid technique to enhance solubility and dissolution

profile of poorly water soluble drugs

Madhavi Kasturi*

Department of Pharmaceutics, Smriti Collge of Pharmaceutical Education,

Indore, M.P, India – 452010

Abstract

“Liquisolid Technique” also known as “Powder Solution Technology” is considered

as new, safe and economic technique aiming for solubility and dissolution

enhancement which further increases the bioavailability of poorly water-soluble

drugs. This technique is based on the admixture of liquid medication with

appropriate carrier and coating materials. Liquid medication includes drug loaded

solutions or suspensions in non-volatile hydrophilic solvents such as PEG 400, PEG

600, Tween 80 etc. The use of hydrophilic non-volatile solvents causes improved

wettability and ensures molecular dispersion of the drug in the formulation that

leads to enhanced solubility. On the other hand, liquid medications containing

drug loaded emulsions by using hydrophobic nonvolatile solvents (vegetable oils),

one can modify release (sustained release) of drugs by this technique. Liquid

medication is combined with a carrier material (Avicel PH 102) having good

absorption properties and coating material (Aerosil 200) having high adsorptive

properties to obtain nonadherent, free-flowing readily compressible powder. It

is further mixed with disintegrants to form immediate release compacts. Hence

both immediate and sustained release of drug can be achieved with the help of

liquisolid technique. The liquisolid powder system can be transformed to

conventional solid dosage forms by compressing into tablets or filled into

capsules. By using this technique, solubility and dissolution rate can be improved

for poorly water-soluble drugs. The postulated mechanism for improved

solubility is due to their significantly improved wetting properties a greater

drug surface area is exposed to the dissolution media, resulting in an increased

dissolution rate and bioavailability. This technique proved an efficient method

for formulating water-soluble as well water-insoluble drugs.

Keywords: Liquisolid technique, carrier material, coating material, solubility

*Corresponding Author: [email protected]

mailto:[email protected]





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Polymeric Microparticles containing herbal plant extracts for

managemet of diabetes

Neelima Salvi* and Choudhary

School of Pharmacy, Devi Ahilya Vishwavidyalaya, Indore, M.P, India –

452001

Abstract

Diabetes cannot be cured completely. Incidence of diabetes mellitus

increasing day by day. Synthetic drugs which are used for the treatment

of diabetes have many side effects and frequency of dosing is more. To

overcome such problems novel carrier system has been chose. Herbal

extracts have been widely accepted as the potential medicines with less

side effects as compared to synthetic drug molecules. Biodegradable

polymers are having wide use for the preparation of vesicular system to

control the drug release pattern of drugs. “Polymeric microparticles”

considered as novel carrier technique to control the release of herbal

plant extracts from vesicular system. Extraction of crude drugs (Hovenia

dulcis) done with successive solvent extraction method by using different

solvents like Petroleum ether, ethyl acetate, chloroform, methanol, and

ethanol. In phytochemical screening we found different constituents of

the plant but Dihydromyricetin, a flavonoid isolated, which decreases

blood glucose level. Polymeric microparticles formulated with hot melt

method and emulsification method. After characterization the

microparticles which are made from hot melt method shows good results

of drug release and entrapment efficiency. In the current research work

micoparticles has been developed of chitosan employed to enhance the

drug release. Polymeric micopartcles were characterized and evaluated

for antidiabetic activity. Hovenia dulcis decrease the blood glucose level in

albino rats

*Corresponding Author: Neelima Salvi, [email protected]






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Theraputic Profile of Mucuna pruriense Linn.

Priyanka Singh*, Yukta Karam Chandani, Nirmal Dongre and Sanjay

Jain

Indore Institute of Pharmacy, Indore.

Abstract

Mucuna pruriense (Valvet bean) is amazing herbal drug, It is tropical

legume native of Africa and tropical Asia, Belongs to family Fabaceae.

Mucuna pruriense is an established herbal drug used for the management

of male infertility, nervous disorders, and also as an aphrodisiac. It has

been shown that its seeds are potentially of substantial medicinal

importance. The ancient Indian medical system, Ayurveda, traditionally

used M. pruriens, even to treat such things as Parkinson's disease. M.

pruriens has been shown to have anti-parkinson and neuroprotective

effects, which may be related to its anti-oxidant activity. It also shows

antidibetic activity. Mucuna pruriens var. utilis, an underutilized tropical

legume has a nutritional quality comparable to soya beans and other

conventional legumes as it contains similar proportions of protein, lipid,

minerals, and other nutrients.In this review the medicinal properties of M.

pruriens are summarized.

Keywords: Mucuna pruriens, Phytochemicals, Antioxidant, Parkinson's

disease, Skin, Diabetes

*Corresponding Author: Priyanka Singh

https://en.wikipedia.org/wiki/Fabaceae





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WHO Guidelines for Herbals

Deepanshi Saklecha* Anjali Soni, Divya Goswami,Nirmal Dongre and

Sanjay Jain


Abstract

Herbal medicines are the oldest form of healthcare known to humanity

and has been used in all cultures throughout history. Quality control and

standardization Reduce adulterations with substandard drugs, improper

authentication, scientific validation of the therapeutic claims, Identity,

purity, efficacy and safety Customer satisfaction and confidence.

Mistaken use of wrong species incorrect dosing, Poor quality products,

Toxicity Interactions with other medicines.Misconception that all herbs

are safe Misuse of herbal drugs Safety in quality management. To

overcome these problems World Health Organization (WHO) issues

Guidelines for herbals A set of guideline for the assessment of herbal

remedies has been published by WHO. These guidelines specify criteria to

be used in evaluating commercial crude drugs intended for use (WHO

Traditional Medicine Strategy 2002-2005). WHO guidelines on safety

monitoring of herbal medicines in pharmacovigilance systems (2004). By

following the guidelines of WHO, we can ensure the quality and Safety of

herbals.In this Review we summarize the guidelines provided by WHO.

Keywords: - WHO, Traditional Medicine

*Corresponding Author: Deepanshi Saklecha





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Study of effect of Curcuma Zeodaria roscoe. on oxidative-stress

animal model

Elangovan Manivannan*, Rajesh Sharma, Narendra Shinde

School of Pharmacy, Devi Ahilya Vishwavidyalaya, Ring Road, Indore-

452001 (M.P.), India.

Abstract

Reactive oxygen species (ROS) have been implicated in many human

diseases such as inflammation, arthritis, cardiovascular aliments, cancer,

diabetes, Alzheimer's disease, and various forms of neurodegenerative

disorders. Curcuma Zeodaria Roscoe., a plant species has been valued in

Indian system of traditional medicine for treatment of wide range of

diseases and reported to have its therapeutic benefit through its

antioxidant property. Thus, the present study was aimed to investigate

the antioxidant potential of rhizome extract of Curcuma Zeodaria Roscoe.

The methanol extract of rhizome was prepared and investigated using in

vitro assays, scavenging ability against 2,2'-diphenyl-2-picrylhydrazyl

(DPPH), and in vivo anti-oxidant potential by cold-immobilization induced

oxidative stress animal model. The maximum antioxidant activities were

observed with minimum concentration, >100 µg/ml of methanol extract of

Curcuma Zeodaria by DPPH based free radical scavenging assay. In the

cold-immobilization oxidative stress study, it was observed that the

Curcuma Zeodaria extract treatment decreased the increased level of

lipid peroxide in liver and brain tissues very significantly. The

histopathological examination of liver and brain tissues showed a

significant protective effect of Curcuma Zeodaria extract against strong

free-radical damage.

Keywords: Curcuma Zeodaria Roscoe; Oxidative-stress; Reactive oxygen

species; Antioxidant

*Corresponding Author: Elangovan Manivannan





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Herbal Hand sanitizer: Need for today

Virendra Singh Rathore*, Shubham Sharma, Nayany Sharma and

Sanjay Jain

Indore Institute of Pharmacy

Abstract

Hands are the most common mode of transmission of the microorganisms

or other infections so hand hygiene plays important role in preventing the

acquired infections. Use of hand sanitizers can help in prevention, control

and reduction of the healthcare acquired infections. Hand sanitizers can

stop transmission of microorganisms from one hand to different parts of

the body and also to other people. Nosocomial infections are increasing

alarmingly and have emerged as a critical issue in hospital care outcome.

Hand sanitization is the preeminent aid in preventing infections caused by

different opportunistic microorganisms and to get this, the use of hand

sanitizer becomes must in recent circumstances. Hand sanitizer avoids

adverse effects like itching, irritation, dermatitis etc. Plants are the rich

source of primary and secondary plant metabolites having particular

therapeutic activities. If the microorganisms reach in to the blood stream

and end up in many different body sites causes wound infections,

abscesses, osteomyelitis, endocarditis and pneumonia.

Keywords: Hand sanitization, Noscomial infections

*Corresponding Author: Virendra Singh Rathore





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Quality Control Parameters For Herbal Drugs and Formulations

Twinkle Copuhan*, Sneha Sable, Shanu Muchhala, Nirmal Dongre and

Sanjay Jain


Abstract

The use of herbal medicine is increasing in developed countries due to

increasing awareness and general acceptability of herbal drugs in today’s

medical practice. Although, most of these applications are unorthodox, it

is however a known fact that over 80% of the world population depends on

herbal medicines and product for healthy living. This rise in the use of

herbal product has also given rise to various forms of abuse and

adulteration of the products leading to consumers’ and manufacturers’

disappointment and in some instances fatal consequences. The challenge is

innumerable and enormous, making the global herbal market unsafe. This

review seeks to enlighten stakeholders in herbal medicine on the need to

establish quality parameters for collection, handling, processing and

production of herbal medicine as well as employ such parameters in

ensuring the safety of the global herbal market. The processes of good

quality assurance and standardization of herbal medicines and products

were also discussed.

Key words: Herbal medicine, standardization, quality control.

*Corresponding Author: Twinkle Copuhan





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Virtual Screening of Phyto-constituents as anticancer agents

Nidhi Gupta*, Love Kumar Soni

School of Pharmacy, Devi Ahilya University, Khandwa Road ,

Indore 452001(M.P.)

Abstract

Protein tyrosine kinase (PTKs) are key enzymes in cell signalling pathway

and play crucial role in a wide variety of diseases including cancer. PTKs

are the enzymes, which catalyzes the transfer of the γ phosphate of ATP

to tyrosine residues on protein substrates. The Phosphorylation of

tyrosine residue is one of the key covalent modifications which modulates

the enzymatic activity and creates the binding sites for the recruitment

of downstream signalling proteins. To overcome the adverse effects of

synthetic compounds curcumin and resveratrol is taken as a herbal

medicine for treating life threatening disease cancer. In order to gain

most potent and lead compound as a tyrosine kinase inhibitors Docking

studies of both compounds have been performed on Pdb:1M17 by using

Molegro Virtual Docker(MVD) 6.0 software. Common amino –acid bindings

are observed in both compounds which show similar interaction as

mentioned in the pdb data base. Docking study revealed that Steric and

H-bonding interactions play significant role against receptor tyrosine

kinase enzyme for their anticancer activity. Docking score and similar

amino-acid binding interactions provide us an idea for designing of new

lead and more potent analogues.

Key-words : Protein Tyrosine kinase, Curcumin, Resveratrol, Docking,

Anticancer activity.

*Corresponding Author: Nidhi Gupta





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Tribal medicines used in treatment of psoriasis

Gaurav patidar*, Aditi Verma, Aditya Jain, Hemant Khambete, Sanjay

Jain

Indore Institute of Pharmacy, Indore

Abstract

Psoriasis is a skin condition that results in patches of skin with silvery

scales, and red and flaky areas that can be itchy, sore, or sometimes

painful. The most common areas affected are the scalp, elbows, knees, and

lower back, although any skin surface may be involved. It can also occur in

the nails and body folds. Psoriasis is not contagious and cannot be passed

from person to person, but it can occur in members of the same family.

Psoriasis starts as small red bumps, which enlarge and become scaly. The

skin appears thick, but bleeds easily if the scales are picked or rubbed

off. The exact cause of psoriasis is unknown, but it is believed that a

combination of factors contributes to the development of the condition.

An abnormality in the immune system causes inflammation in the skin,

triggering new skin cells to develop too quickly.

There are many treatments for psoriasis. Some treatments slow the

production of new skin cells, while others relieve itching and dry skin.

There are various tribal herbal drugs used for treatment of psoriasis that

mainly includes Aloe Vera, Apple Cider Vinegar, Capsaicin, Dead Sea Salts,

Oats, Tea tree oil, Turmeric and Mahonia Aquifolium (Oregon grape). The

present review focus on various herbal treatment approaches for

psoriasis.

Key Words: Psoriasis, Herbal, Aloe, Capsaicin, Skin disease

*Corresponding Author: Gaurav Patidar





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A Review On Ethnomedicine Of Bhil Tribe Of Jhabua District

Ayush Soni*, Kundan Patidar, Harshit Kurmi, Deepak Saad

Swami Vivekanand College Of Pharmacy, Indore (M.P)

Abstract

The Bhils are inhabitants of Dhar, Jhabua, Khargone and Ratlam distrcits

of Madhya Pradesh. A large number of Bhils live in the neighbouring

States of Maharashtra, Gujarat and Rajasthan. They constitute the third

largest tribe of India; the first two being Gonds and Santhals. They

utilize a large number of plant species occurring wild in the district as

herbal remedies in various diseases and ailments. An ethno-medico-

botanical survey was conducted in the tribal blocks. Viz. Kathiware,

Alirajpur and Sodhwa blocks of Jhabua district, M. P. The authors have

gathered first-hand information on seventy – five plant species and their

mode of therapeutic uses from the tribal medicine men ‘Badwa’ and other

experienced tribals. The present study has brought of light some

interesting data on potential medicinal plants which will be screened for

determining their therapeutic and pharmacodynamic properties.

*Corresponding Author: Ayush Soni, [email protected]






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A Review on Medicinal Plants used by the Tribal People of Satna

District, M.P.

Kundan Patidar*, Ayush Soni, Harshit Kurmi, Dishant Gupta

Swami Vivekananda College Of Pharmacy, Indore, (M.P.)

Abstract

Gastrointestinal Aliments Are Very Common Among The People Of Our

Country And Tribals Believe That It Is A Root Cause For The Occurrence

Of Several Other Diseases. Modern Synthetic Medicine Has So Far Not

Produced Any Effective Curative Drug. It Only Gives Temporary Relief.

However,Traditional Herbal Medicines Have A Better Remedy For The

Diseases Of Digestive System. In The Present Paper Herbal Preparations

Used For Gastrointestinal Disorders By Tribal And Rural People Of Satna

District, Madhya Pradesh Has Been Discussed. An Effort Is Also Made To

Correlate Modern Uses And Activities Of Plant, With The Plants Used By

Tribals And Rural People For The Curative Purpose Of Gastrointestinal

Disorders.There Are Six Tribe Types Are Dominatingly Exist In The

Satna District.India Has Vast Resources Of Medicinal Plants. The Use Of

The Plants As Medicine Is Nothing New But According To An Estimate

There Are More Than 25000 Effective Herbal Formulations Exist In The

Country. In The Study Area Of Majhgawan Region Only Three Tribes Are

Dominant, Namely Kol, Gond And Mawasi.

Keywords: Tribes. Ethno-medicinal Plants. Gastrointestinal Disorders.

Majhgawan. Satna. Madhya Pradesh

*Corresponding Author: Kundan Patidar, [email protected]

mailto:%[email protected]





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Traditional tribal medicines Aloe-vera used as a anticancer drug

Manoj Gour*,Steffy Mary Chandy, Akshat Singh Baghel,

Nikhil Gupta, Khushali Pinge, Avani Swami

Swami Vivekananda College of Pharmacy, Indore

Abstract

Aloe Vera leaf gel enables the body to heal itself from cancer and also

from the damage caused by radio and chemotherapy that destroys healthy

immune cells crucial for the recovery. Aloe Vera acts as radiation

protectors and inhibits testicular damage from gamma radiation and

reduces cancer. Aloe Vera leaf contains anthraquinones, saccharides,

vitamin E and C, zinc, enzymes, acetyl salicyclic and others. Acemannan is

the major carbohydrate fraction obtained from Aloe Vera leaf. This

fraction promotes wound healing, has antiviral, anticancer and immune

stimulation effect. Compounds extracted from Aloe Vera have been used

as an immunostimulant that aids in fighting cancer. Aloe Vera emodin, an

anthraquinone, has the ability to suppress or inhibit the growth of

malignant cancer cells making it to have antineoplastic properties.

Keywords: Immunostimulant, anthraquinone, chemotherapy

*Corresponding Author: Manoj Gour





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Tribal medicines in mosquito borne diseases

Nafia Rahman*, Aman Mourya, Bhavesh Mathankar, Steffy Mary

Chandy

Swami Vivekananda College Of Pharmacy, Indore

Abstract

Malaria and other mosquito vector borne diseases prevalent globally .In

India, people often have no or limited facilities at their places. Further

due to lack of proper knowledge, local village people have to rely on

traditional medicines for treatment of the disease. Ethnomedicinal plants

and animals commonly used by tribal people to cure malaria and other

fever, in the Meikal hill region of Amarkantak were surveyed and

documented. The study revealed that plants like Van Adarak-zingiber

zerumbet (L) Zingiberceae. Andrographispaniculata Acanthaceae, Vanjira-

Asteraceae, Crinum asiaticum, Centratherum . Traditional tribal medicines

that are used by the tribal peoples for the treatment of malaria fever and

other documentation of tribal medicines for the generation of new

medicine that may be possible to control new communicable &vector borne

diseases like malaria, swine flu, bird flu, etc.

Keywords:Malaria, Ethnomedicinal plants, Zingiberceae, Asanthaceae,

Vanjira-Asteraceae, Crinum asiaticum, bird flu, swine flu.

*Corresponding Author: Nafia Rahman





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Hypoxis in the treatment of HIV/AIDS

Harshita Sharma*

Swami Vivekanand College of Pharmacy, Indore

Abstract

Herbal medicines are often used as primary treatment for HIV/AIDS and

for HIV-related problems. In general, traditional medicines are not well

researched, and are poorly regulated. Two principal African herbal

compounds used for HIV/AIDS treatment in sub-Saharan Africa

include Hypoxishemerocallidea (common name: African potato),

and Sutherlandia. Hypoxis as an immunostimulantfor patients with

HIV/AIDS. A daily dose of 2,400 mg of raw plant is purported to be

therapeutically effective. There is some indirect evidence that sterols

and sterolins, which are found in the root of Hypoxis, have the potential

to enhance immunity.The plant also contains various sterols (β-sitosterol,

stigmasterol) and their glycosides (sterolins) such as β-sitosterol

glycoside and stanols such as sitostanol also called stigmastanol, which

have also been purported to have important biological activity.

Keywords:Immunostimulant, sterolins, Hypoxis.

*Corresponding Author: Harshita Sharma





33

A review on Swine Flu treatment by tribal medicines using Tinospora

cordifolia

Akshat Singh Baghel*, Archana Tiwari , Nikhil Gupta, Manoj Gour ,

Khushali Pinge

Swami Vivekanand College of pharmacy, Indore

Abstract

Tinospora cordifolia is also known as heart leaved moonseed , commonly

known a Giloy. It is divine in medicinal use, it actively fights with many life

threating diseases from the stanvard of the tinospora cordifolia chemical

tinosporaside that is 18-norcherodne diterpene O-glucoside, have the

property of Anti-pyretic which actively fights against the Swine flu n due

to this this is mostly agains it,by building up the immunity readily and

shoes action on antibiotics to fight activity. One more another chemical

Baberine plays Vital role agains Arrhythmia that is irregular Heartbeat

and hyperlipidemia. It also purify the blood so it also fight against the

diabetes and various types of cancer.It also do not have any negative side

effect . The bitter properties present in the drug show anti-periodic

(Preventing regular recurrence of the symptoms of a disease, as in

malaria) and antispasmodic properties which is again helpful in preventing

infectious diseases like dengue, swine flu, malaria etc.

Keywords: hyperlipidemia , Anti-pyretic , life threating diseases

*Corresponding Author: Akshat Singh Baghel





34

A Review On Tribal Medicine The Untapped Treasure

Varsha Gadekar*, Premlata Patel, Rashi Agrawal,Sakshi Laad

Swami Vivekanand Collage of Pharmacy, Indore

Abstract

In recent years, uncontrolled exploitation by Multinationals has resulted in the loss of

the rich biodiversity of India, which has an immense wealth of about 45,000 species of

wild plants of which 7500 species are used for medicinal purposes. The tribal people are

the real custodians of medicinal plants. Dr. Vedavathy (2002) has recently reported the

results of a study carried out between 1994-1998 in Andhra Pradesh. From the Chittoor

district alone they have documented more than a thousand therapies and 500 medicinal

plants. The predominant tribal populations in the district comprise

the yanadi, yerukala, nakkala and the irula tribes.The Herbal Folklore Research Center

(HFRC) with a small multi-disciplinary team comprising an ethno-botanist, a social

anthropologist, two trained taxonomists, an Ayurvedic doctor and four field assistants,

made enthno-botanical surveys during 1994-1998 in the Chittoor district, in Andhra

Pradesh. The surveys were carried out with a non-random purposive sample of the rural

population. 'Snowball and judgmental' selection methods were used to identify

community members who are knowledgeable in medicinal plant identification and usage.

Vedavathy noticed that there is a strong belief among the tribal people that the

efficacy of the therapy is lost if it is revealed to strangers, who have no faith in nature

and their medicine. Fever: If the ailment is followed by fever the first precaution is to

avoid intake of solid food. During the survey the team documented six types of

antipyretic agents such as the decoction of root tubers of (shatavari), Asparagus

racemosus Willd or Cyprus rotundus used by the Yanadi tribe. The Sugalis used the

garlic bulb (Allium sativum Linn), and dry ginger. And the Nakkala tribe used the

decoction of garlic mixed with Andrographis paniculata and Morinda tinctoria root.

Headache: For headache the tribals use either dry ginger or sandal wood paste as

topical application on the forehead and for pain in the scalp region they bandage either

leaves of Delonix elata Gamble or Vitex negundo Linn. For chronic cases they make a

paste of Achyranthes aspera Linn, earthworm and Ocimum basilicum Linn seeds mixed

with a pinch of camphor, which is applied on the head and forehead. If the headache is

followed by fever and eye infection the juice made by pounding ginger, garlic and onion

is given to drink .

Key words:-Uncontrolled exploitation by multinationals, Asparagus racemosus, Allium

sativum

*Corresponding Author: Varsha Gadekar , [email protected]






35

A Review on Potential and Traditional Use of Dioscorea Species (A

Wild Edible Tuber) by the Local People of Similipal Biosphere Reserve,

India

Chetna Mandloi*, Dharita Desai, Aarti Jaiswal, Neelam

Kushwah,Darshana Sharma

Swami Vivekanand College Of Pharmacy, Indore, (M.P.)

Abstract

A number of wild crops remain unexplored in this world and among them some

have excellent medicinal and nutritional properties. India is a harbour of

biodiversity in general and phytodiversity in particular. The plant diversity is

distributed from the Western Ghats to Eastern Ghats, along with the North-

Eastern region and from the Greater Himalayas to the plain of Ganga. Among

these distributed floral regions of the country, the Eastern Ghats are important

due to their rich floral diversity. The forests of Odisha form a major part of

Eastern Ghats in general and the Similipal Biosphere Reserve (SBR) in particular.

The SBR is inhabited by many local communities. The food and medicinal habits

of these communities are not fully explored even today. They are dependent on

the forests of SBR for their food and medicine. Among their collections from

forests, root and tuberous plants play a significant role. The local communities

of SBR use about 89 types of tuberous plants for various purposes. Dioscorea is

one such tuber, having maximum use among the local of SBR. However, less

documentation and no specific reports are available on the food and medicinal

values of the species available in this part of the World. Dioscorea species,

popularly known as Yam worldwide and as Ban Aalu in Odisha, India, is a prime

staple medicinal-food substitute for the majority of rural and local people of

the state of India. Of the 13 Dioscorea species available in SBR, 10 species are

known to be bitter in taste and unpalatable when taken raw. Since less

documentation is available on the Dioscorea species of SBR and their traditional

uses, the present study was focused on the ethnobotany, nutritional and

pharmacological values of these species along its nutraceutical importance.

*Corresponding Author: Chetna Mandloi , [email protected]






36

Tribal medicine Practices in North East India

Deepak Paudel*

Swami Vivekanand College Of Pharmacy, Indore, (M.P.)

Abstract

India is one of the biggest country in terms of diversity and northeast is

heart of its wildlife diversity. Northeast region of the India comprising

states of Arunachal Pradesh, Assam, Manipur,Meghalaya, Mizoram,

Nagaland, Sikkim and Tripura still follow the age old traditional healing

systemsbased on their tribal method & practices. People living the tribal

life style in these regions they live long & are healthier they are using

plant of these regions and thriving on medicinal aspects. Each state is

having its own dialect, plant and resources for meeting out the

requirement of community including health facilities they are important to

region due the terrain of the area. They all adaptherbs, animal parts,

mantras for keeping them healthy. During various studies it was observed

that thetraditional healers in this region belong to different categories

like herbalist, diviners and birth attendantsetc. Their method of

treatment, ethics and significance of traditional healing practices are

discussed inthis abstract. Now, scientific validation and recognition of

traditional healing medicines are urgentlyrequired for revitalizing this

loosing traditional knowledge.

Key words: Diviner, Herbalist, Livelihood, Traditional Healers, Tribes

*Corresponding Author: Deepak paudel





37

Linum usitatissimum (Flaxseed) used in Tribal medicine

Khushali Pinge*, Manoj Gour,Pooja Tiwari and Akshat Singh

Swami Vivekanand College of Pharmacy, Indore, (M.P.)

Abstract

The benefits of flaxseed make it a superfood you need to add to your anti-cancer

eating plan. Ongoing studies like the one at the University of Illinois show that these

sesame seed-sized kernels may prevent serious illness.Experts believe this is due to the

phytochemicals and phytoestrogens as well as the omega-3 fatty acids contained within.

These compounds working together provide a strong protective benefit to our bodies.

Health Benefits of Flaxseed. Cancer protection. Regular consumption of flaxseed may

protect the body from colon cancer, prostate cancer, and breast cancer. Omega-3 fatty

acids prevent cancerous cells from latching onto healthy cells. If cancerous tumors

attempt to form, the lignans contained in flaxseed stop the formation of new blood

supply (anti-angiogenesis) that feeds tumor growth. In other words, they starve the

tumor of their supply of oxygen and nutrients. If cancer cells can’t get these basic

requirements, they are unable to multiply and spread.Flaxseed is the richest dietary

source of lignans, a type of phytoestrogen. A phytoestrogen is a plant nutrient that is

somewhat similar to the female hormone estrogen. Due to this similarity, lignans may

have estrogenic and/or anti-estrogenic effects in the body. Lignans are the nutrients

that are at the center of the controversy regarding whether it is safe for women with

breast cancer to eat flaxseeds.Phytoestrogens are found in a variety of foods, including

soy, flaxseeds, other nuts and seeds, whole grains, and some vegetables and fruit. Most

of the research regarding flaxseed and breast cancer focuses on the lignans found in

flaxseeds, and their potential for weak estrogenic or anti-estrogenic effects in a

woman’s body.Lignans, which are the type of phytoestrogens in flaxseed, can change

estrogen metabolism. In postmenopausal women, lignans can cause the body to produce

less active forms of estrogen. This is believed to potentially reduce breast cancer risk.

There is evidence that adding ground flaxseeds into the diet decreases cell growth in

breast tissue as well. Again, this would be the type of change that would be expected to

decrease breast cancer risk.

Keywords:- kernels, lignans, phytoestrogen, consumption, metabolism, controversy,

latching.

*Corresponding Author: Khushali Pinge





38

Tribal medicine to treat Schizophrenia

Vrishti Thakur*, Ankita Tikariya, Aayushi Dhangar, Satyaendra

Shrivastava

Swami Vivekanand College Of Pharmacy Indore (M.P.) India

Abstract

Schizophrenia is a subtle disorder of brain development and plasticity; it

affects the most basic human processes of perception, emotion, and judgment.

In the traditional medical practitioners of rural and remote areas characterized

the schizophrenia as an insanity or a mental problem due to possession by ghosts

or evil spirits and they have used various plant species’ to treat such symptoms.

The aim of the present study was to conduct an ethnomedicinal plant survey and

documentation of the formulations of different plant parts used by the

traditional medical practitioners for the treatment of schizophrenia like

psychosis. It was observed that the traditional medical practitioners used a

total of 15 plant species to make 14 formulations. The plants were divided into

13 families, used for treatment of schizophrenia and accompanying symptoms

like hallucination, depression, oversleeping or insomnia, deterioration of personal

hygiene, forgetfulness, and fear due to evil spirits like genies or ghost. A search

of the relevant scientific literatures showed that a number of plants used by

the medicinal practitioners have been scientifically validated in their uses and

traditional medicinal knowledge has been a means towards the discovery of many

modern medicines. Moreover, the antipsychotic drug reserpine, isolated from

the dried root of Rauvolfia serpentina species, revolutionized the treatment of

schizophrenia. So it is very much possible that formulations of the practitioner,

when examined scientifically in their entireties, can form discovery of lead

compounds which can be used as safe and effective antipsychotic drug to treat

schizophrenia.

Keywords:- Schizophrenia, Ethnomedicinal, Traditional medical practitioner

*Corresponding Author : Vrishti Thakur

.





39

Treatment of musculoskeletal diseases by bonesetter shrub

Harsh Pendharkar* , Priya Jain

Swami Vivekanand College of Pharmacy, Indore, (M.P.)

Abstract

“Tribal medicine is a kind of traditional medicines, which are used by tribes in

the forest. It is still in the primitive form. A study about tribals medicine will be

incomplete without the background of traditional medicine. The term “traditional

medicine” refers to way of protecting and restoring health that existed before

the arrival of modern medicine.The Bonesetter (Cissus quadrangular) shrub

belongs to the family Vitaceae. The typical lquadrangular shape of the stem has

given this plant its species name. It is asucculent creeper found trailing over

bushes and fences. In many of the tribal belts in India the local people have

successfully used this plant to mend skeletal fractures,muscle injuries and

sprains.This plant is also used to treat Amenorrhea or absence of menstruation

and painful menstruation. In Amenorrhea, prepare ash of this plant by crushing

the stem andmixing it with pinch of salt. Then burn it over coal on a slow fire.

Take a pinch or two of this ash along with one teaspoon of clarified butter or

ghee.Administratorthis three times a day for 3-7 days. For injuries, muscular

pain and sprains, grind thewhole plant into a fine paste with equal quantities of

fresh turmeric rhizomes. Applya good amount on the affected parts.The plant of

Bonesetter(Cissus quadrangular) grows commonly in the hotter anddrier regions

of India, including the Deccan peninsula, extendingwest to the lowereastern

slopes of the western Ghats and south to Travencore. It is also widespread

inthe drier parts of Africa and Arabia.

It is researched that many local tribes of India and Africa used many herbs and

treeproduct directly or indirectly to treat their diseases and disorders.

Bonesetter(harjor) is one of them medicinal plant which is used by tribals of

these region.

*Corresponding Author : Harsh Pendharkar





40

Tribal medicine to treat hepatitis B

Priya Gawla*, Satyendra K Shrivastava, P.K. Dubey

Swami Vivekanand College of Pharmacy, Indore (M.P.)

Abstract

The term 'hepatitis' simply means inflammation of the liver. Hepatitis may

be caused by a variety of viruses or other infections, medications, or a

toxin such as alcohol. Hepatitis viruses that can cause injury to liver cells

in addition to hepatitis B include the hepatitis A and hepatitis C viruses.

The hepatitis B virus reproduces in liver cells, but the virus itself is not

the direct cause of damage to the liver. Rather, the presence of the virus

triggers an immune response from the body as the body tries to eliminate

the virus and recover from the infection. This immune response causes

inflammation and may seriously injure liver calls.

Hepatitis B is endemic in Southeast Asia, estimated to infect up to 20%

of the population. Licorice was an ingredient in many of the prescriptions

used in ancient times to treat hepatitis. The root is well-known for its

anti-inflammatory activity. Curcuma (yujin) refers to one of three major

species of curcuma used in Chinese medicine, the other two are turmeric

(huangjiang) and zedoaria (ezhu). It contains a complex essential oil that

regulates blood lipids and treats infectious hepatitis. Ligustrum refers to

the seed of Ligustrum lucidum. It is rich in oleanolic acid, a compound that

appears to be effective in treatment of liver diseases, acting mainly as a

liver-protective agent. Silymarin is a complex flavonoid from Silybum

marianum, its main action is to protect the liver from damage.

Keywords: Hepatitis, ligustrum, oleanolic acid.

*Corresponding Author: Priya Gawla





41

Drumstick tree used as tribal medicine

Nikhil Gupta*,Pooja Tiwari, Akshat Singh Baghel

Manoj Gour, Khushali Pinge, Avani Swami

Swami Vivekananda College of Pharmacy, Indore

Abstract

Drumstick tree is one of the most powerful health-enhancing. Drumstick

tree leaf is best known as an excellent source of nutrition and natural

energy booster. Traditionally drumstick tree has been used medicinally as

an anti-bacterial, anti-viral, anti-diabetes agent, and has been shown to

lower harmful blood fats and high blood pressure. Drumstick flower are

useful in intestinal worm. It balances pitta and kapha. The oil which is

prepared by drumstick tree is useful in skin diseases and diabetes. The

parts of drumstick tree are : drumstick’s root bark, stem bark, leaves,

fruits and seeds are used for therapeutic purposes.. Black variety of

drumstick tree is the most common. Its qualities are Deepana ( improves

digestion ), Kshara – Has alkaline properties Vidaahakrit – causes burning

sensation Sangrahi – Useful to check diarrhoea Hrudya Pittarakta

prakopana: Increases Pitta and vitiates blood Chakshushya – Improves

vision, Kaphavataghna–Decreases imbalanced Kapha and Vata Vidradhi –

Useful in abscess. It helps in quick wound healing of abscess, upon oral

intake and external application as paste. Shvayathu – It is a good anti

inflammatory herb. Visha – Anti toxic. Has detoxifying action. Pleeha –

Useful in spleen related diseases Gulma – Useful in abdominal bloating and

tumors , Ganda Vrana – Useful in lymphadenitis.

Keywords: Anti-bacterial, anti inflammatory , energy booster

*Corresponding Author: Nikhil Gupta





42

Investigation of analgesic activity of polyherbal preparation (Topical

Gel) containing herbal extract

Suman Gehlot1*, Sumeet Dwivedi1, Abhishek Dwivedi2 and S.N.Dwivedi4

1, College of Pharmacy, Dr. APJ Abdul Kalam University, Indore, (M.P.) -

India

2, Department of Pharmacy, RKDF University, Bhopal, (M.P.) - India

Abstract

Available synthetic analgesic drugs have several side effects viz.,

gastritis, gastric ulcer, kidney disorders and cardiac arrhythmias.

Therefore, the use herbs are an important and growing part of the pain-

control and new discoveries are made practically every year. Many of

these drugs commit the side effects like Morphine is responsible do work

against heavy sedation and may elevate mood in distressed patients as do

the antidepressants. Caffeine, release the histamine in more amounts, also

have stimulation. And the use of cannabis like a medicine remains a

debated issue. Analgesic herbs are the therapeutic herbs with analgesic

effect that are commonly known as pain relief herbs or simply the pain

herbs. Analgesic herbs are natural pain reliever that reduce or eliminate

pain. These pain relief herbs are available in the market in analgesic

topical forms like essential oil and analgesic cream- that can be directly

applied at the pain sites- as well as in form of capsules, tea and tinctures

for pain relief. The present paper deals with the formulation and

evaluation of polyherbal preparation containg herbal extract of Nigella

sativa (Seeds), Ocimum sanctum (Leaves), Plumeria alba (Leaves) and

Michelia champaca (Stem). The topical gel was prepared and was further

investigated for its analgesic activity using standard diclofenac gel.

Key-Words: Analgesic activity, Topical gel, Herbal extract, Poly herbal

preparations

*Corresponding Author: Suman Gehlot

[email protected], Mob.+91-9893478497





43

Formulation and Evaluation of herbal oil for the treatment of arthritis

Sumeet Dwivedi1*, Shailesh Gupta2, Satyaendra Shrivastava3 and

Seema Kohli4

1, College of Pharmacy, Dr. APJ Abdul Kalam University, Indore, (M.P.) -

India

2, Department of Pharmacy, SRK University, Bhopal, (M.P.) - India

3, Swami Vivekanand College of Pharmacy, Indore, (M.P.) - India

4, Pharmacy Department, Kalanikaten Polytechnic College, Jabalpur, (M.P.)

- India

Abstract

Rheumatoid arthritis (RA) is a long-term autoimmune disorder that

primarily affects joints. It typically results in warm, swollen,

and painful joints. Pain and stiffness often worsen following rest. Most

commonly, the wrist and hands are involved, with the same joints typically

involved on both sides of the body. The disease may also affect other

parts of the body. This may result in a low red blood cell

count, inflammation around the lungs, and inflammation around the heart.

Fever and low energy may also be present. Often, symptoms come on

gradually over weeks to months. The concept of use of herbal therapy for

the treatment of RA is as ancient as mankind and civilization. Herbal

medicine and therapy are now-a-days widely used by the common people

because of concept of fewer side effects and with a better safety and

security profile as compared to modern allopathic medication. The present

work was aimed to formulate herbal oil using various herbs viz., satavari,

brahmi, ratanjot, harjod, eucalyptus etc. for the treatment of arthritis.

The formulated herbal oil was evaluated and various parameters such as

viscosity, saponification value, pH etc. were determined and are reported

in this paper.

Key-Words: Herbal oil, Rheumatoid Arthritis, Evaluation

*Corresponding Author: Sumeet Dwivedi

[email protected], Mob.+91-9893478497

https://en.wikipedia.org/wiki/Autoimmune_disorder

https://en.wikipedia.org/wiki/Synovial_joints

https://en.wikipedia.org/wiki/Pain

https://en.wikipedia.org/wiki/Anemia

https://en.wikipedia.org/wiki/Anemia

https://en.wikipedia.org/wiki/Pleurisy

https://en.wikipedia.org/wiki/Pericarditis





44

Pharmacognostical, Physicochemical and Chromatographic Evaluation of

Polyherbal Formulation: Navasaya Churna

Dongre Nirmal1*, Dubey P K 2and Shrivastava Virendra3

1 Indore Institute of Pharmacy, Indore.

2 Swami Vivekanand College of Pharmacy, Indore

3 Jaipur National University, Jaipur.

Abstract

Most of the traditional systems of medicines are effective but the need is just

to validate them to assess the quality, quantity and purity of the drugs. To

support the same a polyherbal Ayurvedic powdered formulation Navayasa Churna

which is mentioned in Bhaishajyaratnavali in Pandu roga chikitsa1 and used in the

treatment of Anemeia(pandu),Jaundice(kamala),Heart

diseases(hrdroga),Piles(arsa) and Liver diseases. Navasaya churna is the

composition of Nine ingredients, i.e. Amlaki ,Bibhitaka , Haritaki ,Marica

Pippali,Sunthi,Chitraka,Musta,Vidanga and Lauha bhasma. In the present study a

systematic approach has been evolved and effort has been made to develop well

designed methodology for the standardization of this Formulation. Ingredients

of the formulation, In-house formulation and Marketed formulation were

subjected to organoleptic, microscopic characterization, physico-chemical

analysis and Chromatographic studies. The pharmacognostical evaluation shows

fragments of mesocarp cells, sclereids, tannin contents of Haritaki; Silica

deposition of Amalaki: Unicellular covering Trichomas, stone cells, Rosset cristal

of bibhitaki. In physico-chemical evaluation Tap density, Bulk density, Angle of

repose, Loss on drying, moisture content, ash values viz., acid insoluble ash,

alcohol soluble extractive value, water soluble extractive value as well as pH

value etc. were determined. The Rf values spots obtained in TLC were

determined. The set parameters were found to be simple to evaluate the churna

and can be used as reference standards for the quality control/quality

assurance of Shatavaryadi churna and other related Ayurvedic formulations

comparable to the standards.

Key Words: - Standardisation, Orgenoleptic, Physicochemical.

*Corresponding Author: Nirmal Dongre





45

Formulation and evaluation of new nasal drop using Essential Oil of

Black Mustard (Brassica nigra) for the Management of Bacterial

Rhinosinusitis

Harshit Sharma*, Diksha Tomar, Rakesh Patel, Sanjay Jain

Indore Institute Of Pharmacy, Indore (M.P.), India- 453331

Abstract

Plants are very useful and utilized as medicine due to their medicinal properties.

Medicinal plants are great significance to the health of individuals and

communities. Rhino sinusitis is a significant health problem worldwide. It is an

infection of the nasal passages and the paranasal sinus. Purpose of this research,

to formulate the nasal drop by utilization of essential oil of black mustard

(Brassica nigra) , which is used in the management of bacterial rhino sinusitis.

Essential oil of mustard was isolated by simultaneous steam distillation and

extraction. It contain 79.97% of allyl isothiocynate which is the main component

of mustard essential oil which is responsible for very strong pungent odour

which cause irritation on direct application in high concentration. Nasal drops

were formulated containing different concentration of mustard essential oil and

evaluated for its antimicrobial activity against Gram Positive bacteria (S aureus)

and Gram Negative bacteria (E. coli). The essential oil has a broad-spectrum

antimicrobial activity with inhibition zones in the range of 9.43-13.67 mm in the

concentration range from 100-450µg/ml.

Keywords: Antimicrobial activity, Essential oil of black mustard, nasal drop.

*Corresponding Author: Harshit Sharma, [email protected]





46

Evaluation of Anti-diabetic activity of Poly Herbal Antidiabetic Tablet

Glucomap

Satyaendra K. Shrivastava1*, Nirmal Dongre2, P.K. Dubey1, B.

Shrivastava3 and Pankaj Sharma3

1. Swami Vivekanand College of Pharmacy, Khandwa Road, Indore (M.P)

2, Indore Institute of Pharmacy, Indore, (M.P.)

2. School of Pharmaceutical Sciences, Jaipur National University, Jaipur

(Rajasthan)

Abstract

Plants used to treat diabetes are of considerable interest as they are

recognizing to contain valuable medicinal properties in different parts of the

plant species with desire properties. Several species of plant are used in the

treatment of diabetes, a disease affecting large number of people worldwide.

The present paper deals with antidiabetic activity of polyherbal tablet

containing herbs viz., Enicostama littorale Blume. (whole plant), Phyllanthus niruri

Linn. (bhooamala), Eugenia jamboloma Linn.(seeds), Eugenia jamboloma

Linn.(leaves), Azadirachta indicaA. Juss. (leaves), Terminalia arjuna(bark), Aegle

marmelos L. Correa (leaves) and Momordica charantiaLinn. (fruits). The

formulation (GT-I) was developed as per standard anti-diabetic tablet glucomap

(GT) and anti-diabetic activity was evaluated in alloxan indued model. The data

of the blood glucose level of rats treated with Alloxan (150mg/kg body weight)

produced diabetes within 72 hours. After 72 hours of Alloxan administered the

blood glucose levels of rats were observed. Results indicate effect of

administration of feeding the GT-I & GTM on body weight and fluid intake in

normal and diabetic rats. Also, effect of administration of feeding the GT-I &

GTM on total hemoglobin and urine sugar in normal and diabetic rats were

reported. The anti-hyperglycaemic effect of the GT-I & GTM on the fasting

blood sugar levels on diabetic rats were recorded. It was revealed in present

investigation that the formulated batch GT-I shows significant anti-diabetic

activity hen compared to standard drug Glibencamide and standard formulation

GT.

Keywords: Anti-Diabetes Medicinal Herbs, Glucomap

*Corresponding Author: Satyaendra Shrivastava,Email: [email protected]





47

Tribal medicine’- Antidote to snake venom

Zainab Pandhanawala* and Priya Jain

Swami Vivekanand College of Pharmacy, Indore (M.P.)

Abstract India is a country where most of indigenous tribes exist deep into forest. In the

contemporary world when most of advancements are taking place, these tribes still

rely on the traditional methods using local plants available as an ailment against all

the diseases and wounds.

This abstract focuses on the tribal methods and plants used against Snake Venom,

by various indigenous tribes in India. Snakebite has been a major cause of

mortality across the tropical countries including Indian subcontinent. a variety of

literature sources the data has been compiled mentioning the plants, parts used,

dosage, mode of administration, name of the ethnic communities, geographical

locations etc. depending on the availability of information. Since time immemorial

human society has developed amidst with the plant-life. Snakebite, a medical

emergency encountered in the tropics and estimated 35,000 to 50,000 people die

of snakebite every year in India The common poisonous snakes found in India are

Cobra (Naja naja), Krait (Bangarus caeruleus), Russell's viper (Daboia russelli) and

Saw-scaled viper (Echis carinatus). The report contains plants such as Acanthus

ilcifolius, opium sativum, Barleria cristata etc used by various tribes in

tamilnadu,central india and uttar pradesh etc. To conclude, this aims to attract the

focus of researchers on the pharmacological uses of this plant and contribute

towards the advancement of pharmacy.

*Corresponding Author





48

An institute is As Good As the People Behind it.

Our Faculty Dr. P.K. Dubey

Director

Dr. Shikha Agarwal Mr. Satyendra K. shrivastav Dr. Nimita Manocha Mr. Dishant Gupta ( Vice Principal) (Acedmic Dean) ( Professor) (HOD)

Dr. Priya Jain

Dr. Priya Jain Mr. Rupesh Pandey Mrs. Priyanka Pandey Mrs. Steffy Chandy

(HOD) (HOD) (Assistant Professor) (Assistant Professor)

Miss Pooja Tiwari Mrs. Archana Tiwari Mrs. Khusboo Arora Mrs Dharshan Sharma

(Assistant Professor ) (Assistant Professor ) (Assistant Professor) (Assistant Professor)

Mrs.Pooja Pancholi Miss.Ankita Mane

(Assistant Professor ) (Assistant Professor )

Documents

National Seminar on“ Potential of tribal medicine to treat ... s/Archive-2017... · National Seminar on“ Potential of tribal medicine to treat life threatening diseases” on