FINAL EXAMDECEMBER.2011

Time : 3 hours

PATHOLOGY

PAPER- I

NATIONAL BOARD OF EXAMINATIONS

PATHO/D/1113211

Max. Marks :100

Attempt all questions in order.Each question carries 10 marks.

1. Classify glomerular diseases. Discuss the immune and non-immune pathogenesis of glomerulonephritis.

a. Classiff vasculitis.b. Describe the pathology of small vessel vasculitis.

3. a. Mention the common site of origin of osteogenic sarcoma.b. Describe the different histological subtypes of osteogenic

sarcoma.

4. a. Define cirrhosis.b. Enumerate the causes of cirrhosis.c. Describe the method of evaluation of core biopsy of liver in

cirrhosis.

5. a. Write down the pathogenesis of celiac disease.b. Describe the pathological features of this disease.

6. a. Classify interstitial pneumonias.b. Describe the pathology of usual interstitial pneumonia.

7. a. Enumerate the different histological subtypes of breastcarcinoma.

b. Discuss the prognostic factors of breast carcinoma.

8. Describe the immunophenotypic and cytogenetic changes ofperipheral B cell neoplasms.

9. Describe the cutaneous manifestations and chromosomalaberrations in familial cancer syndromes.

10. Describe the pathogenesis and pathology of Grave's disease.

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tPOSSESIONruSE OF CELL PHONES OR ANY SUC,H ELECTRONIC GADGETS IS NOT PE.qMITTED INSIDE THE

EXAMINATION HALL

FINAL EXAMDECEMBER.2011

NATIONAL BOARD OF EXAMINATIONS

PATHOLOGY

PAPER- IITime :3 hoursMax. Marks : 100

Attempt all questions in order.Each question carries 10 marks.

PATHO/D/I1t32il1

a. Enumerate the causes of disseminated intravascularcoagulation (DlC).

b. Discuss the laboratory diagnosis of DlC.

Describe the hematological manifestation of HIV infection.

Discuss the role of genetic counseling and prenatal diagnosis ininherited bleeding disorders.

a. Discuss the pathogenesis of anemia of chronic diseases.b. Describe the differentiating features of anemia of chronic

diseases from lron deficiency anemia.

Discuss the etiopathogenesis and laboratory diagnosis of bonemarrow failure syndromes in children.

Describe the diagnostic criteria and laboratory investigations in acase of anti-phospholipid antibody syndrome.

a. Describe the pathogenesis of hereditary spherocytosis (HS).b. Discuss the laboratory investigations in a case of HS.

write the diagnostic criteria for multiple myeloma and describethe recent advances in its etiopathogenesis.

a. Enlist the various blood components.b. Enumerate their indications for clinical usage.

Discuss the classification, pathogenesis and prognostic factors ofmyelodysplastic synd romes.

POSSESIONftTSE OF CELL PHOI{ES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THEEXAMINATION HALL

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FINAL EXAMDECEMBER.2011

NATIONAL BOARD OF EXAMINATIONS

PATHOLOGY

PAPER- III

Time : 3 hoursMax. Marks : 100

Attempt all questions in order.Each question carries 10 marks.

PATHOTD/Iil3?Ua

Describe the pathology, pathogenesis and laboratory diagnosisof dengue hemorrhagic fever.

Discuss the glandular lesions of cervix detected by PAP smear.

a. Enumerate the various laboratory tests to detect viralinfection.

b, Describe the different laboratory tests to detect HIV infection..

Discuss the role of morphology and ancillary techniques ininterpretation of urine cytology.

Discuss the role of cyto-morphology and ancillary techniques indifferential diagnosis of small round cell tumour.

Describe the cytology and laboratory investigations of a case ofautoimm une thyroid itis.

Describe the pathophysiology and laboratory diagnosis of chronicrenalfailure (CRF).

What are the methods of cell block preparations and write itsutility in cytological diagnosis?

Describe in detail the laboratory investigation in a patientsuffering from diabetes mellitus.

a, What is the principle of chromatography?b. Describe High Performance Liquid Chromatography and its

applications.

POSSESION/USE OF CELL PHONES OR ANY SACH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THEEXAMINATION HALL

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FINAL EXAMDECEMBER.2017

PATHOLOGY

PAPER. IVr

Time : 3 hours

Max. Marks : 100

Attempt all questions in order.Each question carries 10 marks.

NATIONAL BOARD OF EXAMINATIONS

PATHO/D/1il34,V

1 .

2 .

3.

4.

Describe the pathogenesis and pathology of graft versus hostdisease.

a. Enumerate the various mediators of inflammation.b. Give their: principal sources and action.

a. Describe the mechanisms involved in phagocytosis.b. Discuss the various leucocyte function defects.

a. Write the etiopathogenesis of Systemic Lupus Erythematosus(sLE).

b. bescriUe the morphology of Lupus nephritis.

Discuss the mechanisms of cell injury in chronic alcoholism.

Discuss the regulation of energy balance in obesity.

Discuss the sequence of events occurring in healing of fracturebone.

a. What are the different subtypes of stem cells?b. Enurnerate the role of stem cells in various therapeutic

modalities

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Enumerate various tumor suppressor genes.Describe their important mechanisms of action.

Describe the principle of fluorescence in-situ hybridization(FrsH).Enumerate the various applications of FISH.

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POSSESIONflSE OF CELL PHONES OR ANY SIJCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THEEXAMINATION HALL