302 APPROACH TO ASSESSMENT OF PRE- NATAL ALCOHOL EXPOSURE G.Richardson,M.Scher & N.Dav Drug & Alcohol Epidemiology WPIC 3811 O'Hara St Pittsburgh,PA 15213 The relationship between 2 types of neonatal assessment was studied in order to determine the utility of each for describing the effects of prenatal alcohol exposure. The results reported are from a longitudinal study of alcohol & marijuana use during pregnancy. Women are screened during the 4th prenatal month at which time alcohol & other drug use are measured. Those who are selected into the sample are interviewed at 7 months prenatally & post-delivery, when the infants are also examined. To date, 32 infants have been assessed with the ENEAS & a 21-channel sleep-EEG recording. The averag gestational age is 40.5 weeks; the average birthweight is 3564 grams; & mean Apgar scores are 8.2 & 8.8 at 1 & 5 minutes. Controlling for race, sex, birthweight, alcohol & marijuana use, there were no significant correlations between the two Lester state clusters & EEG state. The orientation cluster was correlated with total # of arousals & # of spontaneous arousals. The range of state cluster was correlated with small body movements & the regulation of state cluster with total # of body movements & movements. Given the pattern of findings, one can that the 2 methods assess different aspects of neurological integration & should be used as complementary techniques. To better describe the range of deviation from normal development, both measures should be used.

Multimethod approach to assessment of prenatal alcohol exposure

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302

~ruLTIMETHOD APPROACH TO ASSESSMENT OF PRENATAL ALCOHOL EXPOSURE G.Richardson,M.Scher& N.Dav Drug & Alcohol Epidemiology WPIC3811 O'Hara St (121~UP) Pittsburgh,PA 15213

The relationship between 2 types of neonatal assessment was studied in order todetermine the utility of each for describingthe effects of prenatal alcohol exposure.

The results reported are from a longitudinal study of alcohol & marijuana useduring pregnancy. Women are screened duringthe 4th prenatal month at which time alcohol& other drug use are measured. Those who areselected into the sample are interviewed at7 months prenatally & post-delivery, whenthe infants are also examined. To date, 32infants have been assessed with the ENEAS &a 21-channel sleep-EEG recording. The averaggestational age is 40.5 weeks; the averagebirthweight is 3564 grams; & mean Apgarscores are 8.2 & 8.8 at 1 & 5 minutes.

Controlling for race, sex, birthweight,alcohol & marijuana use, there were nosignificant correlations between the twoLester state clusters & EEG state. The orientation cluster was correlated with total #of arousals & # of spontaneous arousals. Therange of state cluster was correlated withsmall body movements & the regulation ofstate cluster with total # of body movements& fac~al/sucking movements.

Given the pattern of findings, one can se~

that the 2 methods assess different aspectsof neurological integration & should be usedas complementary techniques. To betterdescribe the range of deviation from normaldevelopment, both measures should be used.