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Contents 02 What are the disease modifying drugs? 03 Who is eligible for these drugs on the NHS? 06 Who prescribes these drugs? 07 Can I pay privately for these drugs? 07 Frequently asked questions – natalizumab 08 Side effects – natalizumab 10 Frequently asked questions – beta interferon and glatiramer acetate 16 Side effects – beta interferon and glatiramer acetate 18 Other disease modifying drugs 20 Further information Disease modifying drugs are not a cure for multiple sclerosis (MS), but they can reduce the number and severity of relapses. One of the drugs licensed for MS, natalizumab (brand name Tysabri), has also been shown to slow the progression of disability over two years. 1,2 It is not yet known whether any of these drugs will slow down the rate of disability in the long term. If you are experiencing relapses with your MS, disease modifying drugs might be a suitable treatment. 3, 4 Unfortunately, research to date has shown that these drugs are of no benet for people with primary progressive MS. 5 Several different disease modifying drugs have been licensed for MS and are available on the NHS for those who meet the criteria: natalizumab (brand name Tysabri) beta interferon 1a (two brands available – Avonex and Rebif) beta interferon 1b (two brands available – Betaferon and Extavia) glatiramer acetate (Copaxone) This booklet might help you decide if disease modifying drugs are a suitable option for you. We look at the differences between these drugs, who is eligible on the NHS, and the practicalities of taking them. You may need to choose between several drugs and this booklet might help with that decision. We also look briey at less commonly used disease modifying drugs and emerging treatments, some of which are expected to apply for licensing in 2009. Disease modifying drugs Fourth edition  August 2009 06 M S Essentials For people living with MS This publication is available in large print (22 point) Call 020 8438 0799 or email infoteam@mssociety.org.uk

MS Essentials 06 Disease Modifying Drugs

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