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Mrs. Fernandez Anatomy & Physiology Honors Chapter 2: The Body’s Chemical Makeup

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Mrs. Fernandez Anatomy & Physiology Honors Chapter 2: The Bodys Chemical Makeup Slide 2 Case Study Investigation You have a friend who is preparing for a charity marathon, but he feels that he is too out of shape to compete with seasoned runners. You go with him to shop for energy drinks that would give him a competitive edge. He finally finds a drink called Endurance that promises to boost an athlete's energy during strenuous competition. Your friend drinks several bottles of Endurance before the race. Your friend collapses after 2 hours of running, only 10 miles into the 26-mile race. The medical team on the scene discovers that your friend is dizzy, vomiting, and breathing rapidly. In addition, his muscles are quickly alternating between very tense and overly relaxed. An on-the-spot examination shows that his heartbeat is rapid, yet his blood pressure is low. Determine the possible body chemistry problems causing this set of conditions. Slide 3 Introduction to Chemistry Studying the human body requires knowledge of the chemistry of the bodys structure and function. -What are the properties? Interactions? Our body is composed of 2 substances: energy and matter. Whats the difference? Much of our energy is released as heat -Homeostasis Most important chemistry to study our body is organic chemistry: compounds that contain carbon. Slide 4 Atoms & Molecules All matter is composed of atoms smallest undividable unit -Different types of atoms called elements Contains 3 subatomic particles - ??? Organized into a periodic table according to chemical properties developed by Mendeleev. Interactive table: www.ptable.com Slide 5 Composed of protons and neutrons in the nucleus, and electron orbitals Atomic mass = P + N Atomic # = P Physical Properties: Boiling point, color, density, hardness, melting point, etc. Atom Structure & Function Slide 6 For most elements, the # of N = # of P. When it differs, the element is called an isotope. -Makes the atomic mass different for same element -Have very similar chemical and physical properties, but greatly differ in nuclear properties. -Radioactive isotopes can cause cancer, and also cure it (radiation therapy). Also used in carbon dating (lets us know how long something has been dead for). Slide 7 Atom Structure & Function Gaining or losing electrons = Ions. -Important for every day body reactions: Na/K pump, nerve impulses, and muscle reactions Discovery Education: Properties of Atoms Slide 8 Properties of Molecules Molecules are true building blocks of our body -Made up of two or more atoms joined by chemical bonds -Used to replace worn down molecules or get energy Pure molecules: 2 or more of the same element -Ex: Oxygen molecule made of 2 O bonded Compounds: 2 or more different elements -Ex: Water, H20 Slide 9 Types of Bonds Ionic: Donating / Receiving electrons between 2 elements -Usually from first two columns (readily lose an electron) and next-to-last column (readily gain electron) - Form strong and rigid bonds = crystalline structure -Ex: Na+Cl- (table salt), Bone matrix (calcium chloride), and nerve impulses -Weaken in water (dissolve) Slide 10 Types of Bonds Covalent Bonds: Sharing of electrons between 2 elements -More characteristic of the biochemical's that make up the human body -Usually only involve C, H, N, O, P & S -Very important in carbon compounds -Dont weaken in water -Ex: hair, skin, rubber, plastic -Breaking down covalent bonds creates energy: metabolism Slide 11 Types of Bonds Hydrogen Bonds: Generally temporary and weak -Partial positive H is attracted to negative O, N, F -Ex: Water! -Gives the glue-like property of adhesiveness (using moisture to stick a cup to a surface) and cohesiveness (water attaching to itself) -Responsible for more of the chemical reactions in our body Slide 12 Gizmo: Element Builder Slide 13 Independent Assignment Work SILENTLY On page 40 answer the CONCEPT CHECK 1-3 Q+A Outline from pg. 40-42 starting at Parts of a Molecule. At least 2 sentences per paragraph as well as all terms and definitions Slide 14 Biochemicals Biochemicals: Organic molecules produced by chemical reactions in living organisms Obtained by eating plants, or animals that have eaten plants. 2 major categories: 1. Bioactive 2. Structural Slide 15 Bioactive Molecules Carry out / promote reactions in the body Ex: Caffeine Slide 16 Structural Molecules Components of the body Ex: Tendons, Nails, Fat Some biochemical have both bioactive & structural properties, such as sugar Slide 17 Biochemical Components Made up of Carbon skeleton and Functional group Carbon Skeleton: carbon atoms held by covalent bonds (can be straight chain, branch, ring, etc) Functional Group: one or more elements responsible for chemical activities Slide 18 Functional Groups Hydroxyl (Alcohol): Made of O ; Helps other molecules dissolve in water. Carbonyl: Transfer electrons and help in bonding Carboxyl: Acid, exchanges hydrogen ions with other atoms Amino: Made of N ; Make up proteins and parts of DNA Phosphate: Made of P, captures and releases energy in body processes Sulfhydryl: Made of S ; Gives unique shapes to molecules when bonded Slide 19 Isomers Same molecular formula, but different structural formula (bonding and arrangement of atoms) May have different physical and chemical properties Ex: Propanol can be 1-propanol (perfumes) or 2-propanol (rubbing alcohol) Slide 20 Chirality The mirror image of itself Described as left handed or right handed, the way your hands are mirror images of each other Ex: Right-handed glucose (sugar) and Left-handed glucose (poison) Slide 21 Independent Assignment Complete the Concept Check on page 42 Questions and Answers On a separate sheet of paper Due Today Please work SILENTLY Slide 22 Acids & Bases pH: How many hydrogen ions are in the water Bases / Alkaline solutions: low concentration of H Bland taste, slimy feel Acids / Acidic solutions: high concentration of H Sharp taste, like lemons and vinegar Slide 23 Acids & Bases Buffers help to neutralize acids and bases to pH of 7 Very important in blood and body fluids Slide 24 CSI Re-Visit Knowing a little more about elements and their role in the body now, is there any new idea you have about our CSI patient? Could an acidic or basic reaction be happening his blood? Slide 25 Human Molecules 4 major organic chemical groups: Lipids Carbohydrates Peptides Nucleic Acids Slide 26