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Molecular Diagnostics - Today and Tomorrow
Leopoldina Symposium24 - 26 June 2012Venice International University, San Servolo, Italy
In alphabetical order:
Carlos Caldas, CambridgeWebster Cavenee, San DiegoHartmut Döhner, UlmRoland Eils, HeidelbergHinrich Gronemeyer, StrasbourgTorsten Haferlach, MunichJörg Hoheisel, HeidelbergMarc Ladanyi, New YorkPeter Lichter, HeidelbergHolger Moch, ZürichChristoph Plass, HeidelbergDaniel Rauh, DortmundMichael Rehli, RegensburgGuido Reifenberger, DüsseldorfFrançois Ringeisen, ParisPeter Schirmacher, HeidelbegRoland Schüle, FreiburgReiner Siebert, Kiel Dominic Smiraglia, New YorkRoman Thomas, CologneEva Wardelmann, ColognePaul Waring, MelbourneWolfgang Wick, HeidelbergAndreas von Deimling, HeidelbergThorsten Zenz, HeidelbergJessica Zucman-Rossi, Paris
Organizers
Reinhard Büttner, CologneWolfgang Eisenmenger, MunichOtmar D. Wiestler, Heidelberg
Conference VenueConference CenterVenice International UniversityIsola di San Servolo30100 Venice, Italy
The island is easily reached with the public transport system of ACTV using line 20 from San Zaccaria, mo-nument stop (it may take 10 minutes).
ContactDr. Jana GrünewaldTel: +49 (0)6221 42-2651 Email: [email protected]
Ms. Carina HeydtTel: +49 (0)221 478-5008Email: [email protected]
Webpagewww.dkfz.de/moldiag2012
Speakers
San Servolo island
Venice
Sunday, 24 June 2012
9:00 Registration10:30 Welcome and Introduction Reinhard Büttner
Session I Diagnosing Hematopoietic Tumors Chair: H.K. Müller-Hermelink10:45 Thorsten Zenz Translating lymphoma genetics into clinical care11:15 Hartmut Döhner Translating genetics of acute myeloid leukemia into clinical care11:45 N.N. 12:15 Lunch break
Session II Learning from Cancer Genomics Chair: Peter Lichter13:30 Jessica Zucman-Rossi
14:00 Roland Eils Experiences from massive cancer genome sequencing: comparison of sequencing technologies and IT challenges14:30 N.N. 15:00 Peter Lichter 19:30 Special Lecture: Torsten Haferlach Molecular diagnostics of leukemias Chair: Christof von Kalle
Monday, 25 June 2012
Session III Mapping Genomes and Methylomes Chair: Christoph Plass8:30 Reiner Siebert (Epi)Genomicprofilingoflymphomas9:00 Dominic Smiraglia
9:30 Michael Rehli Epigeneticprofilingofacutemyeloidleukemia10:00 Carlos Caldas Genomic landscapes of breast cancer: inter and intra tumor heterogeneity10:30 Coffee break
Session IV Deciphering Epigenetics Chair: Roland Schüle11:00 Hinrich Gronemeyer 11:30 Christoph Plass Epigeneticprofilinginchroniclymphocytic leukemia12:00 Roland Schüle In vivo functions of the histone demethylase LSD112:30 N.N. 13:00 Lunch break
Session V Predictive Pathology Chair: Reinhard Büttner14:30 Peter Schirmacher Implementation of molecular diagnostic testing - The true challenge of translational diagnostic15:00 Paul Waring Molecularly – directed, signal –seeking clinical trials in refractory cancer15:30 Eva Wardelmann 16:00 Coffee break Session VI Oncogene Dependencies in Lung Cancer Chair: Roman Thomas16:30 Daniel Rauh Chemical oncology – converging cancer genetics, structural biology and medicinal chemistry
17:00 Marc Ladanyi Comprehensive clinical genotyping of lung cancers: new targets, new technologies, new challenges17:30 Roman Thomas 19:30 François Ringeisen
Tuesday, 26 June 2012
Session VII Neurooncology Chair: Otmar D. Wiestler9:00 Andreas von Deimling From DNA sequence analysis to immunohistochemistry: Detection of IDH1 and BRAF mutations9:30 Webster Cavenee PTEN phosphorylation as a biomarker of resistance to targeted therapy10:00 Wolfgang Wick Relevance of MGMT promoter methylation in glioma depends on IDH1 mutational status10:30 Guido Reifenberger Molecular diagnostics of gliomas: MGMT,1p/19q, and beyond
11:00 Coffee break Session VIII Proteome Diagnostics Chair: Holger Moch11:30 Holger Moch Driver gene alterations and tumor surface proteome12:00 Jörg Hoheisel Affinity-based,quantitativeproteomic analysis of pancreatic cancer. 12:30 Wrap-up and Farewell Otmar D. Wiestler
