1) Briefly explain what is a conserved motif

2) Briefly explain what is the difference between a local and a global sequence alignment

3) Briefly explain how you would construct a phylogenetic supertree.

4) List the three main branches of the Gene Ontology (GO) annotation system.

5) Briefly describe the Minkowski distance

6) Briefly describe how BLAST works.

Long questions: Answer 1 out of 3.

1) Write an essay presenting the development of sequence alignment tools.

2) Write an essay on horizontal gene transfer (HGT) and the in silico tools used to detect it.

3) Describe a computational approach to gene finding that is based on markov models.