Mitosis Meiosis 1

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    Mitosis and MeiosisCell Division

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    Why Do Cells Divide?

    For growth, repair, and

    reproduction

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    Mitosis

    Organisms grow by theadditionof cells

    In multicellular organismsome of these cells

    perform functions dierentfrom other cells.

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    he process of a cellbecoming dierent is

    diferentiation. !nder normal conditionsonce an animal cell becomes

    speciali"ed it can nolongerform an entire organism,however plant cells are

    totipotent and any cell canform an entire plant.

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    When do cells divide?

    Most limiting factor in si"e isthe si"e of the cell membrane.Cells must obtain nutrients

    as volume increases, cellsurface area does not increaseas greatly

    larger cells re#uire a largersurface area for survival

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    Cell Division vs. $uclearDivision

    Cyto%inesis& he actual division of thecell into two new cells.

    Mitosis& he division of the nucleus ofthe cell into two new nuclei.

    $ote& 'ometimes cells go throughmitosis without going throughcyto%inesis. Describe a cell that did this.

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    erminology

    Chromatin( thin )brousform of D$* and proteins

    Sister chromatids(identical structures that

    result from chromosomereplication, formed during 'phase

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    *natomy of a

    Chromosome Centromere(

    point where sisterchromatids are

    +oined together

    Pshort arm-upward

    Qlong arm-

    downward

    Telomere(tips ofchromosome

    p -arm

    centromere

    q-arm

    telomerechromatids

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    ow Do Cells Divide/

    Cell cycle( se#uence ofphases in the life cycle of

    the cell

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    Getting ready to split

    Cell cycle has two parts:

    growth and preparation

    0interphase1cell division

    mitosis 0nuclear division1cyto%inesis 0cytoplasm division1

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    Interphase

    Occurs betweendivisions

    2ongest part of cycle 3 stages

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    Interphase

    45 or 4ap 5

    he cell +ust )nisheddividing so in 4ap 5the cell is recovering

    from mitosis

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    Interphase

    ' or 'ynthesis

    stageD$* replicates

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    Interphase

    4 6 or 4ap 6

    his is preparationfor mitosis

    Organelles are

    replicated.More growthoccurs.

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    MITOSIS

    Mitosis begins after G 2 and ends

    before G 1

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    7rophase

    Chromosome

    condense Microtubles form

    he nuclear

    envelope brea%sdown

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    Metaphase

    Chromosomes

    are pulled tocenter of cell

    2ine up along8metaphaseplate9

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    *naphase

    Centromeres divide 'pindle )bers pullone set of

    chromosomes toeach pole

    7recise alignmentis critical todivision

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    elophase

    $uclear envelope form aroundchromosomes

    Chromosomes uncoil

    Cyto%inesisanimals ( pinching of plasma

    membrane

    plants( elongates and the cell plateforms0 future cellwall and cellmembrane1

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    Meiosis

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    What is Meiosis?

    A division of the nucleus that reduces

    chromosome number by half.

    Important in sexual reproduction

    Involves combining the genetic

    information of one parent with that of

    the the other parent to produce a

    genetically distinct individual

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    erminology

    Diploid( two sets ofchromosomes 06n1, in

    humans 63 pairs or :; total Haploid( one set of

    chromosomes 0n1 ( gametesor se< cells, in humans 63chromosomes

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    Chromosome 7airing

    Homologous pair

    each chromosome in pair

    are identical to the other0 carry genes for same trait1

    only one pair diers ( se

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    7hases of Meiosis

    * diploid cell replicates itschromosomes

    wo stages of meiosis

    Meiosis I and Meiosis II

    Only 5 replication

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    Synapsis( pairing ofhomologous chromosomes

    forming a tetrad.Crossing over( chromatidsof tetrad e

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    Meiosis I

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    7rophase I

    Chromosomes condense

    omologous chromosomes pair

    w? each other @ach pair contains four sister

    chromatids ( tetrad

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    Metaphase I

    etrads or

    homologouschromosomes move to

    center ofcell

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    *naphase I

    omologou

    schromosomes pulled to

    oppositepoles

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    elophase I

    Daughter

    nucleiformed

    hese arehaploid 05n1

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    Meiosis II

    Daughter cells undergo a

    second division- muchli%e mitosis

    NO ADDITIONA!"#ICATION OCC$!S

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    7rophase II

    'pindle

    )bers formagain

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    Metaphase II

    'isterchromatidsmove to thecenter

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    *naphase II

    Centromeressplit

    Individualchromosome

    s are pulledto poles

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    elophase II A

    Cyto%inesis Four haploid

    daughtercells resultsfrom one

    originaldiploid cell

    ev ew os s

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    ev ew os sMeiosis

    oth are forms of nucleardivision

    oth involve replication

    oth involve disappearance ofthe nucleus, and nucleolus,

    nuclear membrane oth involve formation ofspindle )bers

    DI%%"!"NC"S

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    DI%%"!"NC"S &eiosisproduces daughter cells that

    have 1/2the number of chromosomesas the parent. 4o from 6n to 5n.

    Daughter cellsproduced by meiosis

    are notgenetically identicalto oneanother.

    In meiosiscell division ta%es placetwice but replication occurs onlyonce.

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    alue of ariation

    'ariation( dierencesbetween members of apopulation.

    Meiosis results in randomseparationof chromosomes ingametes.

    Causes diverse populationsthat over time can be strongerfor survival.