ISMB Symposium 29–30 June 2016 B01 Lecture Theatre, Clore Management CentreBirkbeck College, Torrington Square, London WC1E 7HX

At the interface of Structural, Chemical,

Computational and Cell Biology

w.ismb.lon.ac.uk

Wednesday 29 June – Day 109:30–09:55 Registration – Tea and Coffee in the foyer

09:55–10:00 Opening CommentsProf Geraint Rees, Dean, Faculty of Life Sciences, UCL

Structural Biology Programme10:00–10:45 ‘RNA-protein complexes in RNA metabolism: an integrative structural biology’

Prof Teresa Carlomagno, EMBL Heidelberg, Germany

10:45–11:30 ‘Structural studies of eukaryotic transcription’Dr Alan Cheung, Institute of Structural Biology, London, UK

11:30–11:45 15 minute break – Tea and Coffee in the foyer

11:45–12:30 ‘Mechanism of action of Tc toxins’Prof Stefan Raunser, Max Planck Institute of Molecular Physiology, Dortmund, Germany

12:30–13:30 Lunch break Please note: lunch is not provided as part of the ISMB Symposium, but there are a number of sandwich shops, cafes and restaurants nearby.

Computational Biology Programme13:30–14:15 ‘Co-Evolution Based Methods: new methods and applications’

Prof Alfonso Valencia, CNIO, Barcelona, Spain

14:15–15:00 ‘Chance and necessity: the computational analysis of antibody structure’Prof Anna Tramontano, Sapienza University, Rome, Italy

15:00–15:15 15 minute break – Tea and Coffee in the foyer

Biophysics and Proteomics Programme15:15–16:00 ‘Biochemical methods for protein-lipid networks’

Dr Anne-Claude Gavin, EMBL Heidelberg, Germany

16:00–16:45 ‘The power of correlative super-resolution imaging’Dr Aleksandra Radenovic, EPFL, Lausanne, Switzerland

ISMB Symposium 29–30 June 2016 B01 Lecture Theatre, Clore Management CentreBirkbeck College, Torrington Square, London WC1E 7HX

At the interface of Structural, Chemical,

Computational and Cell Biology

www.ismb.lon.ac.uk

Thursday 30 June – Day 2 Biochemistry and Cell Biology Programme

10:00–10:45 ‘BAR-domain proteins in a test tube’Prof Patricia Bassereau, Institut Curie, Paris, France

10:45–11:30 ‘Cellular senescence in regeneration and development: every cloud has a silver lining’Dr Max Yun, Institute of Structural and Molecular Biology, London, UK

11:30–11:45 15 minute break – Tea and Coffee in the foyer

11:45–12:30 ‘Epigenetic switching: sensing and remembering winter’Prof Caroline Dean, John Innes Centre, Norwich, UK

12:30–13:30 Lunch break Please note: lunch is not provided as part of the ISMB Symposium, but there are a number of sandwich shops, cafes and restaurants nearby.

Chemical Biology Programme13:30–14:15 ‘Systems chemistry: Chemical selection at the origins of life’

Dr Matthew Powner, Institute of Structural and Molecular Biology, London, UK

14:15–15:00 ‘Ligand discovery and anti-cancer therapeutics: from the bench to the clinic’Prof Dario Neri, ETH, Zurich, Switzerland

15:00–15:15 Closing CommentsProf Nicholas Keep, Executive Dean, School of Science, Birkbeck College