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Mentor’s advice
Peer advice
Why a fellowship
Write aCompelling storyPilot data
Letters of recommendation
What budget can be used for
Goal setting
MSTP Fellowship and Career Development SupportAlison Hall, Ph.D.
Office of Graduate Education
Career Development
De-Mystifying the Process
1.Support as an MSTP student1. Fellowship—NIH F30/312. Non-federal funding
2. Next funding steps after graduation1. Career Development—NIH K082. Independence—NIH K02/R01
3. Components of an effective proposal
• National Research Service Awards (NRSA)– F30, 31 Predoctoral Fellowships– F32 Postdoctoral Fellowships
• Career Development Awards– K01 Mentored Research Scientist Development
Awd– K08 Mentored Clinical Scientist Development Awd– K23 Mentored Patient-Oriented Research – K99/00 Pathway to Independence Award
Who has NIH support?
NIH Reporter http://projectreporter.nih.gov/reporter.cfm
Examples…Graduate Education Office..
The NIH NRSA Ruth L Kirschstein
Stipend FY 2011Predoctoral $21,600
Postdoctoral Years of Experience:0 $38,4961 $40,548
TuitionTraining Related ExpensesPredoctoral Trainees: $4,200Postdoctoral Trainees: $7,850
F awardhttp://grants.nih.gov/training/f_files_nrsa.htmF KIOSK
Up to 3 years funding
Tips and samples http://grants.nih.gov/grants/grant_tips.htm_process.htm
Deadlines 3 times per year usu Apr 8, Aug 8, Dec 8
electronic submissions!
F30 / 31 funding for MSTP students
F31 Diversity PA-11-112 for URM students supports PhD phase, includes most institutes
F31 NIH PA-11-111* supports PhD phase
F30 Parent MD-PhD NIH PA-11-110* supports MD and PhD phases
*NCI, NIA, NIAAA, NIDCD, NIDCR, NIDA, NIMH, NINDS, NCCAM
NRSA predoctoral proposal components:
Specific Aims (1 page) 3 aimsResearch Strategy (6 pages)Sponsor/co-sponsor infoRespective Contribution (1 page)Responsible Conduct of Research (1 page)Goals for fellowship training and career (1 page)Activities planned under this award (1 page)Dissertation and other research experience (2 pages)
Three letters of referenceBiosketch including courses and gradesMore than research--incorporate training goals
Reviewer Criterion ScoresApplicantSponsors, collaboratorsResearch Training PlanTraining PotentialInstitutional environment, commitment to training
new techniquesnew collaboratorspresent at meetings, go to coursestimeline including publication planadvisory committee meet six mos for feedback
Non-Federal (Foundations, Corporations, etc)
Grantsnet
Advanced search“Research Funding” , Individual “early doctoral student” “PhD dissertation student”Research area (optional, choose many)
Often single deadline per year
…Plan to apply to Feds and Foundations
Example
American Society Of Microbiology Robert D. Watkins Minority Graduate Fellowshiphttp://www.asm.org/Education/index.asp?bid=6278
3 yearsgraduate coursework completed by activation datementored by an ASM memberMay 1 deadline annually
Example
American Heart Association(Great Rivers affiliate)
Cardiovascular and stroke research
$22,000 plus $1K fringe1-2 years, option 3
Jan deadline, starts July
Inform Cliff before preparing the application
MSTP specific instructions maximum allowable period, 6 yr max on an NIH training mechanism
Choose best funding for MD-PhD training incl covering the MD phase if possible
Project max. training period, max. tuition—
anything left over will revert back to the NIH
Career Development AwardsK01 Mentored Research Scientist Development AwdK08 Mentored Clinical Scientist Development AwdK23 Mentored Patient-Oriented Research K99/00 Pathway to Independence Award
Provides protected time for mentored research
Get pilot data during residency/fellowship
2. Next funding steps after graduation
K08 Mentored Clinical Scientist Development AwardK Kiosk http://grants.nih.gov/training/careerdevelopmentawards.htm
For clinically trained persons to pursue research careers in basic or clinical sciences
Must apply within 3 years of clinical trainingpartial salary (up to $100K)
some research costs (30-50K) up to five years
Not uniform salary—see Institute!! (this is NCI)75% effort (50% surgery)
The K08
Three letters of referenceSpecific aims 1 page
All in 12 pages:Candidates backgroundCareer goals and objectivesCareer development plan/ training activitiesTraining in RCRResearch Strategy
The K08
AGAIN
Career Development Plan (very important)
• learn new techniques, new area, fundable
• present at meetings, review grants, courses
• Update didactics
• Timeline including publication plan
• advisory committee familiar with research, career goals, meet six mos for feedback
Copyright restrictions may apply.
Dickler, H. B. et al. JAMA 2007;297:2496-2501.
First-Time Applicants for R01 Grants by Degree (1964-2004) and Percentage Awarded (1964-2003)
# physician investigators applying for first R01s
little change for 3 decadesThose proposing clinical work less successful
MD-PhDs are few, but successful!
3. Components of an effective proposal
Most applications electronic
Assigned to Scientific Review GroupStudy section review
NIH Scores 1 (great)- 9 (poor)Summary sheet
http://grants.nih.gov/grants/partners/NexusImages/September06/submit.jpg
Write for the Reviewers
• Reviewers are:– Smart– Accomplished– Dedicated– Fair
Phyllis McBride, [email protected]
Write for the Reviewers
• Reviewers are also:– Busy– Overworked– Skeptical– May not be as
knowledgeable about the details
Phyllis McBride, [email protected]
What is the benefit of answering your question?Who will it help and how?
Make a definitive statement on purpose of your researchwhy it should be funded
A strong research idea passes the “so what” test
Specific Aims (1 p max)
Propose 2 or 3 aims
Provide a rationale—where did hypothesis come from? why is this a strong idea?
Provide a hypothesis to be tested with a specific aim
Have objectives that are measurable and focused
Research Strategy (6 p max)
background and significance no more than a pagenot a wikipedia on the subject!!lead to remaining question each paragraph
Pilot data--perhaps a year of work? Plan to submit right after qualifier
Research Strategy, continued
How test hypothesis, what approach?
Propose to learn two techniques within planDescribe who will teach you and howInclude collaborators, letters as needed
Cite, but do not expect reviewer to read papers
Provide general scope of experiment
Include “Anticipated outcome and Alternative interpretations” for each aim
Sponsor/co-sponsor inforesearch expertisetraining experience and successmay need to choose add’l senior persondescribe when meet
Responsible Conduct of ResearchIBMS 500 + advanced ethics
Goals for fellowship training and careerthesis committee composition, mtgscoursework CSH, other instnspublications, national meetingsProfessional skills