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Megavoltage Radiation Therapy for Axial and Inoperable Giant-Cell Tumor of Bone* by ARNAB CHAKRAVARTI, IRA J. SPIRO, EUGEN B. HUG, HENRY J. MANKIN, JIMMY T. EFIRD, and HERMAN D. SUIT J Bone Joint Surg Am Volume 81(11):1566-73 November 1, 1999 ©1999 by The Journal of Bone and Joint Surgery, Inc.

Megavoltage Radiation Therapy for Axial and Inoperable Giant-Cell Tumor of Bone* by ARNAB CHAKRAVARTI, IRA J. SPIRO, EUGEN B. HUG, HENRY J. MANKIN, JIMMY

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Page 1: Megavoltage Radiation Therapy for Axial and Inoperable Giant-Cell Tumor of Bone* by ARNAB CHAKRAVARTI, IRA J. SPIRO, EUGEN B. HUG, HENRY J. MANKIN, JIMMY

Megavoltage Radiation Therapy for Axial and Inoperable Giant-Cell Tumor of Bone*

by ARNAB CHAKRAVARTI, IRA J. SPIRO, EUGEN B. HUG, HENRY J. MANKIN, JIMMY T. EFIRD, and HERMAN D. SUIT

J Bone Joint Surg AmVolume 81(11):1566-73

November 1, 1999

©1999 by The Journal of Bone and Joint Surgery, Inc.

Page 2: Megavoltage Radiation Therapy for Axial and Inoperable Giant-Cell Tumor of Bone* by ARNAB CHAKRAVARTI, IRA J. SPIRO, EUGEN B. HUG, HENRY J. MANKIN, JIMMY

Figs. 1-A, 1-B, and 1-C: Case 4.

ARNAB CHAKRAVARTI et al. J Bone Joint Surg Am 1999;81:1566-73

©1999 by The Journal of Bone and Joint Surgery, Inc.

Page 3: Megavoltage Radiation Therapy for Axial and Inoperable Giant-Cell Tumor of Bone* by ARNAB CHAKRAVARTI, IRA J. SPIRO, EUGEN B. HUG, HENRY J. MANKIN, JIMMY

Fig. 1-B One year after treatment, there was complete eradication of the soft-tissue component with osseous remodeling and postirradiation osseous changes (arrow).

ARNAB CHAKRAVARTI et al. J Bone Joint Surg Am 1999;81:1566-73

©1999 by The Journal of Bone and Joint Surgery, Inc.

Page 4: Megavoltage Radiation Therapy for Axial and Inoperable Giant-Cell Tumor of Bone* by ARNAB CHAKRAVARTI, IRA J. SPIRO, EUGEN B. HUG, HENRY J. MANKIN, JIMMY

Fig. 1-C Ten years after treatment, there was no evidence of disease.

ARNAB CHAKRAVARTI et al. J Bone Joint Surg Am 1999;81:1566-73

©1999 by The Journal of Bone and Joint Surgery, Inc.

Page 5: Megavoltage Radiation Therapy for Axial and Inoperable Giant-Cell Tumor of Bone* by ARNAB CHAKRAVARTI, IRA J. SPIRO, EUGEN B. HUG, HENRY J. MANKIN, JIMMY

Fig. 2 Graph showing the actuarial rate of lack of disease progression for the twenty patients who were managed with radiation, with or without an operation.

ARNAB CHAKRAVARTI et al. J Bone Joint Surg Am 1999;81:1566-73

©1999 by The Journal of Bone and Joint Surgery, Inc.