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UNITED Scientific Group A non-profit organization Exhibitor MEDPATH-2020 FIRST EDITION MEDICAL PATHOLOGY FEBRUARY 17-19, 2020 DoubleTree by Hilton Houston Intercontinental Airport 15747 John F. Kennedy Blvd. Houston, TX 77032 USA The event invitation code is: Medpath We are excited to use Whova as our event platform. Attendees please download Whova event app.

MEDPATH-2020 · Alexion is a global biopharmaceutical company focused on serving patients and families affected by rare diseases through the discovery, development and commercialization

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UNITED Scientific Group

A non-profit organization

Exhibitor

MED

PATH

-202

0FI

RST E

DITIO

N MEDICAL PATHOLOGY

FEBRUARY17-19, 2020

DoubleTree by Hilton Houston Intercontinental Airport

15747 John F. Kennedy Blvd.Houston, TX 77032 USA

The event invitation code is: Medpath

We are excited to use Whova as our event platform. Attendees please download Whova event app.

Alexion is a global biopharmaceutical company focused on serving patients and families affected by rare diseases through the discovery, development and commercialization of life-changing therapies.

Breakthrough Therapies

Through the transformative power of our science, Alexion has delivered life-changing ther-apies to patients suffering from rare diseases. We have pioneered the complex field of complement biology and delivered solutions to challenges that once seemed impossible for patients living with rare and devastating diseases.

Alexion has developed and delivered therapies for the treatment of complement-mediated diseases – two for patients with paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS), and one for patients with anti-aquaporin-4 (AQP4) an-tibody positive neuromyelitis optica spectrum disorder (NMOSD) and anti-acetylcholine receptor (AchR) antibody-positive generalized myasthenia gravis (gMG).

Alexion also has two highly innovative enzyme replacement therapies for patients with life-threatening and ultra-rare metabolic disorders—hypophosphatasia (HPP) and lysosom-al acid lipase deficiency (LAL-D).

Venue Floor

07:50-08:00 Introduction to MedPath-2020 @ Seattle I

Keynote Session @ Seattle I

08:00-08:30 Andy N.D. Nguyen, University of Texas-Houston, Houston, TX The Coming Digital Pathology Revolution: Diagnostic Systems for Whole Slide Imaging

08:30-09:00 Carl Morrison, Roswell Park Comprehensive Cancer Center, Buffalo, NY Pathologists as Gatekeepers to Precision Medicine

09:00-09:30 Robert E. Brown, UTHealth McGovern Medical School, Houston, TX M2 Macrophages in Crystal Storing Histiocytosis Associated with Plasma Cell Myeloma

09:30-10:00 Agnieszka Wiktiewicz, Roswell Park Comprehensive Cancer Center, Buffalo, NY Precision Medicine in Pancreatic Cancer: The Importance of Orthogonal Approaches to Target A

Therapy Recalcitrant Diseases

10:00 -10:20 Coffee Break @ Prefunction Foyer

Session-I @ Seattle I

Hematopathology | Laboratory Medicine

Chairs: Morayma Reyes Gil, Montefiore Medical Center, Bronx, NY Eleanor M. Travers, Private Medical Practice, Philadelphia, PA

10:20-10:40 Morayma Reyes Gil, Montefiore Medical Center, Bronx, NY Artificial Intelligence to Identify Neutrophil Extracellular Traps in Peripheral Blood Smears

10:40-11:00 Jie-Gen Jiang, Rutgers New Jersey Medical School, Newark, NJ Plasma Cell Myeloma with Dual Expression of Kappa and Lambda Light Chains

11:00-11:20 Wei Cui, The University of Kansas Medical Center, Kansan City, KS p53 Expression in Large B-cell Lymphomas with MYC Extra Copies and CD99 Expression in Large

B-cell Lymphomas in Relation to MYC Status

11:20-11:40 Ling Guo, Ohio State University Wexner Medical Center, Columbus, OH Ultrasensitive Automated RNA in situ Hybridization for Kappa and Lambda Light Chain mRNA

Detects B-cell Clonality in Tissue Biopsies with Performance Comparable or Superior to Flow Cytometry

11:40-12:00 Katsiaryna Laziuk, University of Missouri School of Medicine, Columbia, MO T -cell Lymphoma/Leukemias: The Uncommon & Rare

12:00-12:20 Yaseen Mohiuddin, University of Michigan Medical School, Ann Arbor, MI An Uncommon Presentation of Diffuse Large B-cell Lymphoma as a Pleural Based Cavitary Lesion

12:20-12:40 Beata Grygalewicz, Maria Sklodowska-Curie Institute Oncology Center, Poland Is the Duplication and Deletion of 11q a Specific Change only for Burkitt-like Lymphoma with 11q

Aberrations?

DaY...One Feb 17Monday

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07:30-07:50 Registrations & Badge Pick-up @ Prefunction Foyer

12:40-13:00 Michelle Lin, Houston Methodist Hospital, Houston, TX Mullerian-Type Clear Cell Carcinoma of the Testis: An Extremely Rare Occurrence with Unique

Clinical Presentation

13:00-13:20 Lei Chen, The University of Texas Health Science Center McGovern Medical School, Houston, TX Acute Leukemia of Ambiguous Lineage Presents with Pelvic Mass and Retroperitoneal

Lymphadenopathy

13:20-14:00 Lunch Break @ Dallas/Houston

14:00-14:20 C. Cameron Yin, University of Texas MD Anderson Cancer Center, Houston, TX Clinical Applications of Next-generation Sequencing in the Diagnosis, Risk Stratification and

Target Therapy of Myeloid Neoplasms

14:20-14:40 Jie Xu, MD Anderson Cancer Center, Houston, TX Lymphomas Being Potential Candidates for PD-1 Blockade Immunotherapy

14:40-15:00 Min Shi, Mayo Clinic, Rochester, MN Mixed-Phenotype Large Granular Lymphocytic Leukemia: A Rare Subtype in the Large Granular

Lymphocytic Leukemia Spectrum

15:00-15:20 Ji Yuan, University of Nebraska Medical Center, Omaha, NE Application of Flow Cytometry in Diagnosis of Chronic Myelomonocytic Leukemia

15:20-15:40 Eleanor M. Travers, Private Medical Practice, Philadelphia, PA Prescriptive Visual Informatics Reporting of Early Scientific “Trigger Signals” with a Diagnostic

Critical Path (DCP) API to Avert Adverse Diagnostic Events in High Risk Patients

15:40-16:00 Katell Peoc’h, University of Paris, France Clinical Biomarkers of Acute Mesenteric Ischemia: First Results from the SURVIBIO Trial

16:00-16:20 Coffee Break @ Prefunction Foyer

16:20- 16:40 Alden E Chesney, VCU Medical Center, Richmond, VA Interference of Daratumumab with Flow Cytometric Assessment of Plasma Cell Myeloma

16:40-17:00 Weijie Li, UMKC School of Medicine, Kansas, MO Flow Cytometry Detection of Normal/ Reactive Minor Cell Populations in Peripheral Blood and

Bone Marrow: Phenotypic Features and Clinical Significance

17:00-17:20 Lisa Maness, Winston-Salem State University, Winston-Salem, NC The Inhibitory Effect of Essential Oils on Rhizopus stolonifer, Trichophyton mentagrophytes, and

Microsporum gypseum

17:20-17:40 Lian-Wang Guo, The Ohio State University, Columbus, OH Nullifying Epigenetic Writer DOT1L Attenuates Intimal Hyperplasia

17:40-18:00 Shinya Tajima, St. Marianna University School of Medicine, Japan Nuclear Inverse Polarity Papillary Lesions with Lack of Myoepithelial Cells: A Report of the Two

Cases

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Session-II @ Seattle I

Anatomical | Neuro | Surgical | Diagnostic | Toxicologic

Chairs: Thomas Weber, University of Hamburg, Germany Larry Nichols, Mercer University School of Medicine, Macon, GA

08:00-08:20 Kanwaljit Aulakh, Pathology Laboratory Associates, Tulsa, OK Data Warehouse Strategies and the Modern Anatomic Pathology Laboratory: Quality

Management, Patient Safety, and Pathology Productivity Issues and Opportunities

08:20-08:40 Larry Nichols, Mercer University School of Medicine, Macon, GA Must Anatomic Pathologists Surrender the Diagnosis of Fungal Hyphae to the Microbiology

Laboratory?

08:40-09:00 Charles M Lombard, El Camino Hospital, Los Altos Hills, CA The Pathogenesis of Pulmonary Lymphangioleiomyomatosis

09:00-09:20 Louis Maximilian Buja, UTHealth McGovern Medical School, Houston, TX Diagnostic Surgical Pathology of Aortic Diseases

09:20-09:40 Karla Lais Pegas, Santa Casa de Misericordia Hospital, Brazil Cancer: What if it were an Infectious Disease?

09:40-10:00 Steven J Soldin, NIH, Bethesda, MD The Role of Mass Spectrometry in Optimizing the Diagnosis and Treatment of Thyroid Disease

10:00-10:20 Coffee Break @ Prefunction Foyer

10:20-10:40 Thomas Weber, University of Hamburg, Germany Laboratory Diagnostics in Dementia

10:40-11:00 Maria Del Carmen Dominguez Grandal, University Hospital Complex of Vigo, Spain Cystinuria: The Importance of Sediment

11:00-11:20 Michael Punsoni, University of Nebraska Medical Center, Omaha, NE Diagnostic Criteria of Diffuse Gliomas and Implications for Management

11:20-11:40 Edwin Roger Parra Cuentas, The University of Texas MD Anderson Cancer Center, Houston, TX Cancer Immunoprofiling Using Multiplexed Platforms and Biomarker Discovery

11:40-12:00 Agata Zieba-Wicher, Navinci Diagnostics, Sweden The Next Generation in situ Staining for Improved Protein Detection

12:00-12:20 Wenbin Tan, University of South Carolina School of Medicine, Columbia, SC Molecular Pathogenesis of Port Wine Stain Blood Vessels

12:20-12:40 Maram Abdaljaleel, University of Jordan, Jordan CD34 Immunostain Increases the Sensitivity of Fetal Vascular Malperfusion Diagnosis in Placentas

of Stillbirths

12:40-13:00 Neda Zarrin-Khameh, Baylor College of Medicine, Houston, TX Fine Needle Aspiration of Alveolar Soft Part Sarcoma

DaY...Two Feb 18Tuesday

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13:00-14:00 Lunch Break @ Dallas/Houston

14:00-14:20 Donghwa Baek, Houston Methodist Hospital, Houston, TX Monophasic Epithelial Synovial Sarcoma Initially Diagnosed as Metastatic Adenocarcinoma of

Unknown Primary

14:20-14:40 Daniel O’Conor, Baylor College of Medicine, Houston, TX Musculoskeletal Injuries in Spaceflight

14:40-15:00 Vasanthi Mowat, Covance CRS Ltd, UK Interpreting Adversity of Histopathological Findings in Safety Assessment Studies

15:00-15:20 Shunhua Guo, Indiana University School of Medicine, Indianapolis, IN Vasculitis Manifested as Multiple Mass Lesions

15:20-15:40 Erika Resetkova, UT MD Anderson Cancer Center, Houston, TX Diagnosis, Classification and Current Therapeutic Approaches to High Risk Lesions of the Breast

in the UT MD Anderson Cancer Center

15:40-16:00 Coffee Break @ Prefunction Foyer

16:00-16:20 Marja Nevalainen, Medical College of Wisconsin, Wauwatosa, WI Positive STAT5 Protein and Locus Amplification Status Predicts Recurrence after Radical

Prostatectomy to Assist Clinical Precision Management of Prostate Cancer

16:20-16:40 Carlos P. Sosa, Mayo Clinic, Eagan, MN mRNA Expression-Based and Novel Fusions Detection in Genitourinary Cancers: Prognosis and

Discovery

16:40-17:00 Adam L. Booth, University of Texas Medical Branch, Galveston, TX Implementation of a Novel Patient-Pathologist Consultation Program and Survey of Patient

Experience

17:00-17:20 Ke (Corey) Xu, St. Jude Children’s Research Hospital, Memphis, TN Structure and Evolution of Double Minutes in Diagnosis and Relapse Brain Tumors

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17:20-18:00 Poster Session @ Prefunction Foyer

P-01 Andrew Rostron, Public Health England, UK Newborn Outcome System (NBO) – Public Health England

P-02 Ding Dai, Virginia Commonwealth University School of Medicine, Richmond, VA A Unique Case Report of Rectal Prolapse as an Initial Manifestation of Malignant Peritoneal Epithelioid

Mesothelioma

P-03 Eduardo Cambruzzi, Santa Casa de Misericordia Hospital, Brazil Silent Corticotroph Pituitary Adenoma: Clinical Course and Histological Findings

P-04 Guangjing Zhu, University of Maryland, Baltimore, MD Hepatocellular Neoplasm in Transplanted Liver: New Versus Recurrent?

P-05 Dietmar Enko, Medical University of Graz, Austria Iron Status Determination with Conventional and New Biomarkers in Patients with Helicobacter pylori

Infection

P-06 Subhashree Mallika Krishnan, Beaumont Hospital, Westland, MI Prevalence of Helicobacter pylori in Sleeve Gastrectomy (SG) Specimens and a Case Report of Large

Ectopic Pancreas Polyp

P-07 Arizumi Kikuchi, Daiyukai Research Institute for Medical Science, Japan Improving MicroRNA Extraction by Reagent Optimization

P-08 Ahsan Siddiqi, Mayo Clinic, Jacksonville, FL Ossifying Granular Cell Tumor

P-09 Ahsan Siddiqi, Mayo Clinic, Jacksonville, FL Metastatic Thyroid Carcinoma to the Kidneys; Presenting as Bilateral Renal Masses: A Rare Case Report

and Literature Review

Session-III @ Seattle IDigital & Computational| Molecular | Onco | Immuno & Forensic Pathology

Chairs: Timothy C. Thompson, MD Anderson Cancer Centre, Houston, TX Elizabeth Chlipala, Premier Laboratory, LLC, Longmont, CO

09:00-09:20 Timothy C. Thompson, MD Anderson Cancer Centre, Houston, TX PARP Inhibition Suppresses GR MYCN CDK5 RB1 E2F1 Signaling and Neuroendocrine

Differentiation in Castration-Resistant Prostate Cancer

09:20-09:40 Elizabeth Chlipala, Premier Laboratory, LLC, Longmont, CO NSH/DPA Online Digital Pathology Certificate of Completion

09:40-10:00 Hua Xu, The University of Texas Health Science Center, Houston, TX Cancer Information Extraction from Pathology Reports Using Natural Language Processing (NLP)

10:00-10:20 Dana Quesinberry, University of Kentucky, Lexington, KY Impact of a Drug Overdose Decedent Toxicology Testing Legislative Mandate on Informing

Coroner Death Investigation and Certification Practices

10:20-10:40 Coffee Break @ Prefunction Foyer

10:40-11:00 Raju C. Reddy, University of Pittsburgh, Pittsburgh, PA Key Functions and Therapeutic Prospects of Nur77 in Inflammation Related Lung Diseases

11:00-11:20 Rongqin Ren, Ohio State University, Columbus, OH Resolving HER2 Discrepancies in Breast Cancer Using Genomic Profiling

11:20-11:40 Torsten Landwehr, LMU Munich, Germany Sports-related Deaths

11:40-12:00 Joshy George, Jackson Laboratory for Genomic Medicine, Farmington, CT Machine Learning in Biology and Medicine

12:00-12:20 Steven J Soldin, NIH, Bethesda, MD The Role of Mass Spectrometry in Optimizing the Diagnosis and Treatment of Adrenal Disease

12:20 Lunch & Departures @ Dallas/Houston

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UNITED Scientific Group

A non-profit organization

We wish to see youat

MedPath-2021Houston, TX

# 8105, Rasor Blvd - Suite #112, PLANO, TX 75024, USAPh: +1-469-854-2280/81; Toll Free: +1-844-395-4102; Fax: +1-469-854-2278

Email: [email protected]: https://medicalpathology.unitedscientificgroup.org/