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Medical Image Analysis Medical Image Analysis Image Formation Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003.

Medical Image Analysis Image Formation Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003

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Page 1: Medical Image Analysis Image Formation Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003

Medical Image AnalysisMedical Image AnalysisImage Formation

Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003.

Page 2: Medical Image Analysis Image Formation Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003

Color representation◦RGB: red, green, blue◦ISH: intensity, saturation, hue

Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003.

Page 3: Medical Image Analysis Image Formation Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003

Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003.

From www.wikipedia.org

Page 4: Medical Image Analysis Image Formation Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003

Image Coordinate SystemImage Coordinate SystemObject: Image:TranslationRotation

Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003.

),,( f),,( zyxg

Page 5: Medical Image Analysis Image Formation Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003

Image Coordinate SystemImage Coordinate System

Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003.

z

Image-Formation System h

Object Domain

Image Domain

x

y

Radiating Object f() Image g(x,y,z)

Figure 2.1. The object and image domain coordinates systems.

Page 6: Medical Image Analysis Image Formation Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003

Linear Systems and Impulse Linear Systems and Impulse ResponseResponse

Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003.

}{}{}{ 2121 IbhIahbIaIh

Page 7: Medical Image Analysis Image Formation Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003

Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003.

Reconstructed Cross-Sectional Image

Radiation Source

z

Image-Formation Systemh

Object Domain

Image Domain

Selected Cross-Section

x

yRadiating Object

Image

Figure 2.2. A schematic block diagram of a general 3-D image formation system requiring an external radiation source (such as light) for photographic imaging or x-ray for transmission imaging.

Page 8: Medical Image Analysis Image Formation Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003

Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003.

z

Reconstructed Cross-Sectional Image

Image-Formation Systemh

Object Domain

Image Domain

Selected Cross-Section

x

y

Radiating Object

Image

Figure 2.3. A schematic block diagram of an emission based image formation system commonly used for fluorescence or nuclear medicine imaging modalities.

Page 9: Medical Image Analysis Image Formation Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003

Pin-hole ImagingPin-hole Imaging

Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003.

Pin-hole

Object Plane Focal Plane Image Plane

f(x1,y1)

g(x2,y2)z1z2

x

z

y

Figure 2.4. A schematic diagram of a pin-hole imaging camera.

Page 10: Medical Image Analysis Image Formation Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003

Fourier TransformFourier TransformLinearityScalingTranslationConvolutionCross-correlationAuto-correlationParseval’s theoremSeparability

Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003.

Page 11: Medical Image Analysis Image Formation Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003

Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003.

Figure 2.5. (a) A vertical stripe image generated from a sinusoidal waveform of a period of 8 pixels and (b) the logarithmic magnitude image of its Fourier transform

Page 12: Medical Image Analysis Image Formation Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003

Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003.

Figure 2.6. (a) A rotated stripe image and (b) the logarithmic magnitude image of its Fourier transform.

Page 13: Medical Image Analysis Image Formation Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003

Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003.

Figure 2.7. (a) An image with a square region at the center and (b) the logarithmic magnitude image of its Fourier transform.

Page 14: Medical Image Analysis Image Formation Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003

Radon TransformRadon Transform

Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003.

x

y

q

p

p

f(x,y)

P(p,)

Figure 2.8. Line integral projection P(p,q) of the two-dimensional Radon transform.

Page 15: Medical Image Analysis Image Formation Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003

Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003.

Projection p1

Projection p2

Projection p3

Reconstruction Space

A

B

Figure 2.9. A schematic diagram for reconstructing images from projections. Three projections are back-projected to reconstruct objects A and B.

Page 16: Medical Image Analysis Image Formation Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003

SamplingSamplingNyquist rate

Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003.

Figure 2.10. (a) A 2-D distribution of Gaussian impulses in the spatial domain and (b) its representation in the Fourier domain.

Page 17: Medical Image Analysis Image Formation Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003

Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003.

x

y

ymax

xmaxxmax

ymax

Fa(x,y)

(a)

Figure 2.11. (a) The Fouier spectrum of a bandlimited two-dimensional signal; (b) Sampling of the bandlimited signal with a sampling frequency higher than the Nyquist rate; (c). Undersampling of the bandlimited signal with a sampling frequency lower than the Nyquist rate.

Page 18: Medical Image Analysis Image Formation Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003

Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003.

(b)

Page 19: Medical Image Analysis Image Formation Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003

Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003.

(c)

Page 20: Medical Image Analysis Image Formation Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003

Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003.

Figure 2.12. (a) A vertical stripe image generated from a sinusoidal waveform of a period of 1.8 pixels, (b) the logarithmic magnitude image of its Fourier transform, (c) the central cross section of the logarithmic magnitude of the Fourier transform, along the horizontal direction, of the signal shown in Figure 2.5 (a), which is sampled satisfying the Nyquist criterion, and (d) the central cross section along the horizontal direction of the logarithmic magnitude of the Fourier transform of the aliasing pattern shown in Figure 2.12 (a).

Page 21: Medical Image Analysis Image Formation Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003

Over-sampled

Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003.

x

Log |F(x, 0)|

Page 22: Medical Image Analysis Image Formation Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003

Aliasing

Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003.

x

Log |F(x, 0)|

Page 23: Medical Image Analysis Image Formation Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003

Discrete Fourier Discrete Fourier TransformTransform

Figures come from the textbook: Medical Image Analysis, by Atam P. Dhawan, IEEE Press, 2003.

1

0

1

0

)(2),(),(

M

x

N

y

N

yv

M

xuj

eyxfvuF

1

0

1

0

)(2),(

1),(

M

u

N

v

N

yv

M

xuj

evuFMN

yxf