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BMT InfoNet Celebrating a Second Chance at Life Survivorship Symposium
April 17‐23, 2021
Visit www.bmtinfonet.org 1
Managing Sleep Challenges after Transplant
Celebrating a Second Chance at Life Survivorship Symposium
April 17- 23, 2021Eric Zhou PhD
Dana-Farber Cancer Institute
MANAGING SLEEP PROBLEMS AFTER TRANSPLANT
Eric Zhou, PhDAssistant Professor | Harvard Medical School
Staff Psychologist | Dana‐Farber Cancer Institute
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BMT InfoNet Celebrating a Second Chance at Life Survivorship Symposium
April 17‐23, 2021
Visit www.bmtinfonet.org 2
Sleep is Important
HOW MANY HOURS OF SLEEP DO ADULTS NEED PER NIGHT?
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BMT InfoNet Celebrating a Second Chance at Life Survivorship Symposium
April 17‐23, 2021
Visit www.bmtinfonet.org 3
What is Good Sleep?
Quantity
Continuity
Timing
Sleep Quality
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BMT InfoNet Celebrating a Second Chance at Life Survivorship Symposium
April 17‐23, 2021
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Health Consequences
Cardiovascular disease
Diabetes
Obesity
Depression
Anxiety
Behavioral problems
Suicide attempts
Alcohol use
Quality of life
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BMT InfoNet Celebrating a Second Chance at Life Survivorship Symposium
April 17‐23, 2021
Visit www.bmtinfonet.org 5
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BMT InfoNet Celebrating a Second Chance at Life Survivorship Symposium
April 17‐23, 2021
Visit www.bmtinfonet.org 6
Our data suggest that
• an improvement in sleep efficiency by 10%
• among women with sleep efficiency <85%
• could potentially lead to a 32% increase in survival time
CANCER SPECIFIC
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BMT InfoNet Celebrating a Second Chance at Life Survivorship Symposium
April 17‐23, 2021
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• Insomnia disorder
• Obstructive sleep apnea
• Central sleep apnea
• Sleep related hypoventilation disorder
• Sleep related hypoxemia disorder
• Narcolepsy (Type I/II)
• Idiopathic hypersomnia
• Kleine‐Levin syndrome
• Delayed sleep‐wake phase disorder
• Advanced sleep‐wake phase disorder
• Non‐24 sleep‐wake disorder
• Shift work disorder
• Jet lag disorder
• Confusional arousals
• Sleepwalking
• Sleep terrors
• Sleep related eating disorder
• REM sleep behavior disorder
• Sleep enuresis
• Restless legs syndrome
SLEEP DISORDERS
INSOMNIA
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BMT InfoNet Celebrating a Second Chance at Life Survivorship Symposium
April 17‐23, 2021
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INSOMNIA SYMPTOMS ARE COMMON
Insomnia is Trivialized
BMT
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BMT InfoNet Celebrating a Second Chance at Life Survivorship Symposium
April 17‐23, 2021
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SPEAK UP!
91.2%78.1%
60.8%
0%
20%
40%
60%
80%
100%
Mild Moderate Severe
PCP Not Aware of Sleep
Problems
Insomnia Severity
DOCTORS DON’T FIND OUT
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BMT InfoNet Celebrating a Second Chance at Life Survivorship Symposium
April 17‐23, 2021
Visit www.bmtinfonet.org 10
WHEN WAS THE LAST TIME YOUR PCP ASKED
How is your sleep?
WHAT HAVE YOU TRIED TO DO?
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BMT InfoNet Celebrating a Second Chance at Life Survivorship Symposium
April 17‐23, 2021
Visit www.bmtinfonet.org 11
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BMT InfoNet Celebrating a Second Chance at Life Survivorship Symposium
April 17‐23, 2021
Visit www.bmtinfonet.org 12
PRESCRIPTION MEDICATION
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BMT InfoNet Celebrating a Second Chance at Life Survivorship Symposium
April 17‐23, 2021
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Taking an anticholinergic for the equivalent of three years or more was associated with a 54% higher dementia risk
than taking the same dose for three months or less.
MELATONIN
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BMT InfoNet Celebrating a Second Chance at Life Survivorship Symposium
April 17‐23, 2021
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WHAT SHOULD YOU DO?
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BMT InfoNet Celebrating a Second Chance at Life Survivorship Symposium
April 17‐23, 2021
Visit www.bmtinfonet.org 15
WHAT IS CBT-I?
6-8 sessions over 6 months
Sleep restrictionStimulus controlSleep hygieneCognitive therapyRelaxation
Match time in bed to total sleep durationUse bed only for sleepImprove behaviors that affect sleepAddress maladaptive sleep cognitionsPractice relaxation exercises
4 over 2
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BMT InfoNet Celebrating a Second Chance at Life Survivorship Symposium
April 17‐23, 2021
Visit www.bmtinfonet.org 16
YOUR NEW MANTRA
COLLECT DATA
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BMT InfoNet Celebrating a Second Chance at Life Survivorship Symposium
April 17‐23, 2021
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SLEEP DIARIES
SLEEP RESTRICTION
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BMT InfoNet Celebrating a Second Chance at Life Survivorship Symposium
April 17‐23, 2021
Visit www.bmtinfonet.org 18
STIMULUS CONTROL
SLEEP HYGIENE
1. Eliminate the bedroom clock
2. Exercise in the late afternoon/early evening
3. Minimize caffeine, alcohol, and nicotine
4. Eat a light bedtime snack
5. Reduce liquid consumption before bed
6. Reduce electronics use
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BMT InfoNet Celebrating a Second Chance at Life Survivorship Symposium
April 17‐23, 2021
Visit www.bmtinfonet.org 19
If I don’t sleep well tonight, I don’t know
how I’m going to be able to work tomorrow.
This has to stop. My _____ is going to
come back if I don’t sleep.
I’m never going to fall asleep with so much to worry about right now.
COGNITIVE THERAPY
SLEEP OCCURS IN CONTEXT OF LIFE
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BMT InfoNet Celebrating a Second Chance at Life Survivorship Symposium
April 17‐23, 2021
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As Easy As…
www.behavioralsleep.org
FINDING A SPECIALIST
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BMT InfoNet Celebrating a Second Chance at Life Survivorship Symposium
April 17‐23, 2021
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ALTERNATIVES
“The amount of sleep required by the average person is 5 minutes more.”
‐Wilson Mizner
Eric Zhou, [email protected]
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BMT InfoNet Celebrating a Second Chance at Life Survivorship Symposium
April 17‐23, 2021
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Questions?
Celebrating a Second Chance at Life Survivorship Symposium 2021
bmtinfonet.org ✦ [email protected] ✦ 847- 433-3313
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