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BMT InfoNet Celebrating a Second Chance at Life Survivorship Symposium April 1723, 2021 Visit www.bmtinfonet.org 1 Managing Sleep Challenges after Transplant Celebrating a Second Chance at Life Survivorship Symposium April 17- 23, 2021 Eric Zhou PhD Dana-Farber Cancer Institute MANAGING SLEEP PROBLEMS AFTER TRANSPLANT BMT InfoNet [email protected] Eric Zhou, PhD Assistant Professor | Harvard Medical School Staff Psychologist | DanaFarber Cancer Institute 1 2

MANAGING SLEEP PROBLEMS AFTER TRANSPLANT

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BMT InfoNet Celebrating a Second Chance at Life Survivorship Symposium

April 17‐23, 2021

Visit www.bmtinfonet.org 1

Managing Sleep Challenges after Transplant

Celebrating a Second Chance at Life Survivorship Symposium

April 17- 23, 2021Eric Zhou PhD

Dana-Farber Cancer Institute

MANAGING SLEEP PROBLEMS AFTER TRANSPLANT

BMT [email protected]

Eric Zhou, PhDAssistant Professor | Harvard Medical School

Staff Psychologist | Dana‐Farber Cancer Institute

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BMT InfoNet Celebrating a Second Chance at Life Survivorship Symposium

April 17‐23, 2021

Visit www.bmtinfonet.org 2

Sleep is Important

HOW MANY HOURS OF SLEEP DO ADULTS NEED PER NIGHT?

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BMT InfoNet Celebrating a Second Chance at Life Survivorship Symposium

April 17‐23, 2021

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What is Good Sleep?

Quantity

Continuity

Timing

Sleep Quality

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Health Consequences

Cardiovascular disease

Diabetes

Obesity

Depression

Anxiety

Behavioral problems

Suicide attempts

Alcohol use

Quality of life

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April 17‐23, 2021

Visit www.bmtinfonet.org 5

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April 17‐23, 2021

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Our data suggest that 

• an improvement in sleep efficiency by 10% 

• among women with sleep efficiency <85%

• could potentially lead to a 32% increase in survival time

CANCER SPECIFIC

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April 17‐23, 2021

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• Insomnia disorder

• Obstructive sleep apnea

• Central sleep apnea

• Sleep related hypoventilation disorder

• Sleep related hypoxemia disorder

• Narcolepsy (Type I/II)

• Idiopathic hypersomnia

• Kleine‐Levin syndrome

• Delayed sleep‐wake phase disorder

• Advanced sleep‐wake phase disorder

• Non‐24 sleep‐wake disorder

• Shift work disorder

• Jet lag disorder

• Confusional arousals

• Sleepwalking

• Sleep terrors

• Sleep related eating disorder

• REM sleep behavior disorder

• Sleep enuresis

• Restless legs syndrome

SLEEP DISORDERS

INSOMNIA

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INSOMNIA SYMPTOMS ARE COMMON

Insomnia is Trivialized

BMT

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SPEAK UP!

91.2%78.1%

60.8%

0%

20%

40%

60%

80%

100%

Mild Moderate Severe

PCP Not Aware of Sleep 

Problems

Insomnia Severity

DOCTORS DON’T FIND OUT

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WHEN WAS THE LAST TIME YOUR PCP ASKED

How is your sleep?

WHAT HAVE YOU TRIED TO DO?

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PRESCRIPTION MEDICATION

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Taking an anticholinergic for the equivalent of three years or more was associated with a 54% higher dementia risk 

than taking the same dose for three months or less.

MELATONIN

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WHAT SHOULD YOU DO?

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WHAT IS CBT-I?

6-8 sessions over 6 months

Sleep restrictionStimulus controlSleep hygieneCognitive therapyRelaxation

Match time in bed to total sleep durationUse bed only for sleepImprove behaviors that affect sleepAddress maladaptive sleep cognitionsPractice relaxation exercises

4 over 2

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YOUR NEW MANTRA

COLLECT DATA

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SLEEP DIARIES

SLEEP RESTRICTION

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STIMULUS CONTROL

SLEEP HYGIENE

1. Eliminate the bedroom clock

2. Exercise in the late afternoon/early evening

3. Minimize caffeine, alcohol, and nicotine

4. Eat a light bedtime snack

5. Reduce liquid consumption before bed

6. Reduce electronics use

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If I don’t sleep well tonight, I don’t know 

how I’m going to be able to work tomorrow.

This has to stop. My _____ is going to 

come back if I don’t sleep.

I’m never going to fall asleep with so much to worry about right now.

COGNITIVE THERAPY

SLEEP OCCURS IN CONTEXT OF LIFE

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As Easy As…

www.behavioralsleep.org

FINDING A SPECIALIST

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ALTERNATIVES

“The amount of sleep required by the average person is 5 minutes more.”

‐Wilson Mizner

Eric Zhou, [email protected]

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April 17‐23, 2021

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Questions?

Celebrating a Second Chance at Life Survivorship Symposium 2021

bmtinfonet.org ✦ [email protected] ✦ 847- 433-3313

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