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7/30/2019 Liver Scoring Tab
http://slidepdf.com/reader/full/liver-scoring-tab 1/21
Parameter Negative PositiveTumor size <50% of liver (Radio Button) > 50% of liver (Radio Button)
Ascites Absent (Radio Button) Present (Radio Button)
Serum albumin >3 g/dl (Radio Button) < 3 g/dl (Radio Button)
Bilirubin <3 mg/dl (Radio Button) >3 mg/dl (Radio Button)
Okuda Text Box
Score will Calculate Automatically on
the Basis of Below Parameters and
Should Be Displayed in the Text box
Okuda I
Okuda II
Okuda III
Okuda
if No Postive Factor is Selected
if 1 OR 2 Postive Factor is Selected
if 3 OR 4 Postive Factor is Selected
7/30/2019 Liver Scoring Tab
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Parameter Score 0 Score 1
Child- Pugh stage A (RB) B (RB)
Tumour morphlogyUninodular
and extension
<=50%(RB)
Multinodular andextension
<=50%(RB)
AFP (ng/ml) <400 (RB) >400(RB)
Portal vein thrombosis no(RB) Yes(RB)
Clip Stage Text Box
Early Stage if Score is ZERO
Intermediate Stage if score is 1-3 points
Advanced stage if score is 4 - 6 points
CLIP
Score will Calculate Automati
Parameters and Should Be
7/30/2019 Liver Scoring Tab
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Score 2
C (RB)
Massive orextension
>50%(RB)
(RB) Radio Button
only one Radio button will be sel
cally on the Basis of Below
isplayed in the Text box
and final score will be the additionwill be selected
7/30/2019 Liver Scoring Tab
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cted from each row
f corresponding radio button whichn particular row
7/30/2019 Liver Scoring Tab
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BCLC stage PST Tumour stage Okuda stage Liver function staus
Stage A: early HCC 0
A1 0 Single,<5 cm INo portal hypertensionand nomal bilirubin
A2 0 Single,<5 cm I
portal hypertension and
nomal bilirubin
A3 0 Single,<5 cm I
portal hypertension and
abnomal bilirubin
A4 0 3 tumours <3 cm I-II Child - pugh A-B
Stage B: intermediate HCC 0 Large multinodular I-II Child - pugh A-B
Stage C: advanced HCC 1-2*
Vascular invasion or
extrahepatic spread* I-II Child - pugh A-BStage D: end stage HCC 3-Apr Any III Child-Pugh C
BCLCA
B
C
D
BCLC
Drop Down list
Tumour status
Stage A and B: all criteria should be fulfilled.
Stage C: at least one criterion ; *PST 1-2 or vascular invasion /extrahepatic spread.
Stage D: at least one criterion;PST 3-4 or Okuda stage III/ Child -Pugh C.
7/30/2019 Liver Scoring Tab
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this is for Display purpose only
and in the Last Provide a Drop Down.
7/30/2019 Liver Scoring Tab
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Grade
0(RB)
1(RB)
2(RB)
3(RB)4(RB)
5(RB)
ECOG Text Box
RB Radio Button
Dead
Selected Grade will Automatically
E
Fully active, Able to carry on all pre-disease performance without restriction
Restricted in physicallly strenuous activity but ambulatory and able to carry out work o
Ambulatory and capable of all selfcare but unable to carry out any work activities.Up a
Capable of only limited selfcare, confined to bed or chair more then 50% of waking houCompletely disablesd. Cannot carry on any selfcare.Totally confined to bed or chair
7/30/2019 Liver Scoring Tab
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and only one Radio Button will be Selected from the above Categoryisplay in the Text box.
OG
f a light or sedentary nature, e.g., light house work, Office Work
d about more than 50% of waking Hours
rs
ECOG
7/30/2019 Liver Scoring Tab
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Measure 1 point 2 points
Total bilirubin,umol/I(mg/dl) <34(<2)(RB) 34-50(2-3)(RB)
Serum albumin, g/l >35(RB) 28-35(RB)
PT INR <1.7(4)(RB) 1.71-2.20(4-6)(RB)
Ascites None(RB) Mild (RB)
Hepatic encephalopathy None(RB) Grade I-II(RB)
CTP Score Text Box
CTP Score
Score will Calculate Au
Selected Parameters an
7/30/2019 Liver Scoring Tab
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3 points
>50(3)(RB)
<28(RB)
>2.20(>6)(RB)
Severe(RB)
Grade III-IV (or refractory)(RB)
only one Radio button will be sel
and final score will be the addition
omatically on the Basis of Above
d Should Be Displayed in the Text
box
7/30/2019 Liver Scoring Tab
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cted from each row
f corresponding radio button which
7/30/2019 Liver Scoring Tab
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Category Variables Score CategorySex Female (RB) Plus 2 HLA
AP:AST(orALT)ratio >3(RB) Minus2 Immune Disease
<1.5(RB) Plus 2
y globulin or lgG level
above normal >2.0(RB) Plus 3 Other markers
1.5 2.0(RB) Plus 2
<1.0(RB) 0
ANA, SMA, or LKM1 titers >1:80(RB) Plus 3 Histological features
1;80(RB) Plus 2
01:40:00(RB) Plus 1
<1:40(RB) 0
AMA Positve (RB) Minus 4 Treatment response
Viral markers Positive(RB) Minus 3
Negative(RB) Minus 3
Drugs Yes (RB) Minus 4 Pretreatment aggregate score:
No (RB) Plus 1
Alcohol <25 g/day(RB) Plus 2 posttreatment aggregate score:
>60 g/day(RB) Minus 2
Only one will be Selected from
And Please Treat
Plus as + SignAnd Please Treat
Minus as - Sign
RB Radio Button
Probable diagnosis 12 17
ALH SCORE
Definite Diagnosis>15
Probable Diagnosis 10 15
Definite diagnosis >17
7/30/2019 Liver Scoring Tab
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Variables ScoreDR3 Or DR4(RB) Plus 1
Thyroiditis, colitis, others (RB) Plus2
Anti SLA, anti actin, anti LC1,pANCA(RB) Plus 2
Interface hepatitis (RB) Plus 3
Plasmacytic(RB) Plus 1
Rosettes(RB) Plus1
None of above(RB) Minus5
Billary changes(RB) Minus3
other features(RB) Minus3
Complete(RB) Plus2
Relapse(RB) Plus 3
Text Box
Text Box
a Particular Category
Score wi
Above P
Score wi
Above P
7/30/2019 Liver Scoring Tab
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ll Calculate Automatically on the Basis of
rameters and Should Be Displayed in the
Text box
ll Calculate Automatically on the Basis of
rameters and Should Be Displayed in the
Text box
7/30/2019 Liver Scoring Tab
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MELD = 3.78[Ln serum bilirubin (mg/dL)] + 11.2[LnINR] +9.57[LnserumCREATINI
is given a value of 1]
Maddrey's (Discriminant Function ) = 4.6* (PT in seconds prolonged ) + Total bilir
Lilley Model score: Text Box
7/30/2019 Liver Scoring Tab
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E (MG/DL)] +6.43 [Any value less than one
bin
In the Lilley Model Score,
Require
Automatically Take Values
TAB and calculated
Automatically Take Values
TAB and calculated
7/30/2019 Liver Scoring Tab
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only a text box is
rom Investigation
the Score
rom Investigation
the Score
7/30/2019 Liver Scoring Tab
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Mrecist for HCC
only Check Box Required
1 CR=Disappearance of any intratumoral arterial enhancement in all target lesions (Check Box)
2 PR =At least a 30% decrease in the sum of diameters of viable ( enhancement in the arterial ph
3 SD= Any cases that do not qualigy for either partial response or progressive disease (Check Bo
4 PD = An increase of at least 20% in the sum of the diameters of viable (enhancing ) target lesio
7/30/2019 Liver Scoring Tab
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mRECIST
ase)target lesion, taking as reference the baseli
)
ns, taking as reference the smallest sum of the
7/30/2019 Liver Scoring Tab
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ne sum of the diameters of target lesions (Check Box)
diameters of viable ( enhancing ) target lesions recorded since treatment
7/30/2019 Liver Scoring Tab
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tarted (Check Box)