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CAREER VIEW NATURE|Vol 441|22 June 2006 1024 RECRUITERS & ACADEMIA GRADUATE JOURNAL Write and wrong There are many books on scientific methodology, but guidelines for writing a good scientific paper are harder to come by. My month-long battle with a manuscript has made me ponder many aspects of writing. First, there is the choice of scope. The best articles put their subject in a wider framework, but it’s a fine line between relevant and ridiculous parallels. As a sociobiologist, I’m wary of making careless comparisons of ants to humans, despite frequent requests from friends both within and outside science. Then there is the eternal temptation to promise more than your results deliver. My paper is on kin selection and insects. Do I suggest that it will change the way we study ants, the way we see social insects, or the roots of social interaction? The insanely inflated claims of some papers make me side with a friend of mine, who once suggested that articles should include only methods and results, leaving interpretation to the reader. And how much room is there for speculation? Writing my paper has inspired many ideas about my ant system that remain untested. Gratuitous musings may transmit the ideas, but they make many reviewers see red. After weeks of rewrites, I finally submitted my manuscript. At the moment, I have no clear picture of what it says or, indeed, why any of it matters. But I’m hopeful that given some time, I will be pleasantly surprised by my handiwork. Katja Bargum is a graduate student in the Department of Biological and Environmental Sciences at the University of Helsinki, Finland. Since I graduated in 2003 with a bachelor’s in biology, my professional life has been an on-again, off-again drama. Should I move to a graduate programme straight away? Or should I test the waters outside of the hallowed halls of academia? I chose the latter. I'm glad I did. I had little wind left in my jib after four tough years. The challenge has been to remain active and keep my mind astute in the ever- changing fields of biology and ecology. Small, volunteer gigs and journal- reading sufficed for a while, but I soon became more aggressive in applying for full-time positions. I first targeted biology departments and also sought private-sector and federal positions. Many opportunities I saw were for full-time volunteers, most requiring major expense and lasting a short time. Then in early 2005 I spotted a volunteer post at the Primate Habituation Programme at the Dzanga- Ndoki National Park in the Central African Republic. I had never been there and had never worked with primates. With a one-year commitment, I wouldn’t feel like a tourist. I applied, got the position and was soon on my way. The goal of the programme, based at a camp called Bai Hokou, is to acclimatize western lowland gorillas and semi-terrestrial mangabeys to the presence of humans. An eco-tourism programme was set up with the backing of the government, the conservation charity WWF and the German aid agency GTZ. The revenue is placed in a programme for local communities. Tourists have been visiting since 2001, although acclimatization efforts are labour-intensive and ongoing. The position enabled me to witness a new model of wildlife conservation that had to weather poachers and limited government supervision. It was a stark contrast to the carefully choreographed efforts I’d seen in the United States. Because I was either fixing fuses, cooking over a wood fire or following gorillas, I gave little thought to what would come next. So, since coming home, I’m once again excruciatingly over-analysing my career options. I now plan to capitalize on the discipline and intellectual stimulation I gained in the Congo basin by pursuing a master’s degree in evolutionary biology with an emphasis on conservation. In the mean time, I’m doing public presentations about working with wild animals in an effort to raise awareness of conservation issues. Ayres Christ is currently splitting time between Washington DC and Tennessee. A recurring theme of Paul Gilna’s career has been to serve the scientific community while working at the cutting edge of computational biology. His work to set up computational tools and annotated genetic-sequence databases, such as GenBank, has aided the research of countless scientists. After earning a degree in pharmacology at University College Dublin, Gilna pursued a PhD focused on the drugs affecting the hormones oestrogen and progesterone. Advised by mentors to enter the new world of molecular biology, he serendipitously met molecular biologist Pierre Chambon. Gilna’s collaboration with Chambon’s group and colleagues at the University of Chicago in Illinois culminated in the cloning and sequencing of human oestrogen and progesterone receptors. While a postdoc at Chicago, Gilna published papers that would become the basis of current genetic testing for the predisposition to breast cancer. At this point, however, he opted out of research to use the computational-biology skills he had taught himself. A position at GenBank, the annotated collection of publicly available gene sequences at Los Alamos National Laboratory, met his goals. “I was looking for something more tangible as evidence that what I doing was of assistance to others,” he says. Gilna constructed the now familiar requirement that authors of journal articles submit gene sequences to GenBank in exchange for an accession number printed with the article. The procedure made digital data available to researchers and streamlined the process of lifting printed data from journals. He was co-principal investigator until GenBank moved to the National Institutes of Health. After two years at the National Science Foundation, Gilna returned to Los Alamos to oversee the human-genome sequencing arm of the Department of Energy’s Joint Genome Institute. One of his best achievements, he says, was aiding its transition to microbial genome sequencing. His new role is executive director of the CAMERA project, which provides computational and data-analysis tools to decipher the collective genetic codes obtained from as-yet unculturable ocean microbes. The partnership between the J. Craig Venter Institute at the University of California, San Diego, and the San Diego Supercomputer Center will test his ability to lead disparate groups. “The challenge is not only that this is a new partnership, but that it is creating the new field of metagenomics,” he says. Virginia Gewin MOVERS Paul Gilna, executive director, Community Cyber- infrastructure for Advanced Marine Microbial Ecology Research and Analysis (CAMERA) project, San Diego, California 2001–06: Director/manager, Center for Human Genome Studies, Los Alamos National Laboratory (LANL), New Mexico 1998–2000: Programme director, computation biology and database activity programmes, National Science Foundation, Washington DC 1994–98: Programme manager, biology and environmental research, LANL, New Mexico Lessons from the jungle Nature Publishing Group ©2006

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Page 1: Lessons from the jungle

CAREER VIEW NATURE|Vol 441|22 June 2006

1024

RECRUITERS & ACADEMIA

GRADUATE JOURNAL

Write and wrongThere are many books on scientific methodology, but guidelines for writing agood scientific paper are harder to come by. My month-long battle with amanuscript has made me ponder many aspects of writing.

First, there is the choice of scope. The best articles put their subject in a widerframework, but it’s a fine line between relevant and ridiculous parallels. As asociobiologist, I’m wary of making careless comparisons of ants to humans,despite frequent requests from friends both within and outside science.

Then there is the eternal temptation to promise more than your resultsdeliver. My paper is on kin selection and insects. Do I suggest that it will changethe way we study ants, the way we see social insects, or the roots of socialinteraction? The insanely inflated claims of some papers make me side with afriend of mine, who once suggested that articles should include only methodsand results, leaving interpretation to the reader.

And how much room is there for speculation? Writing my paper has inspiredmany ideas about my ant system that remain untested. Gratuitous musingsmay transmit the ideas, but they make many reviewers see red.

After weeks of rewrites, I finally submitted my manuscript. At the moment, I have no clear picture of what it says or, indeed, why any of it matters. But I’mhopeful that given some time, I will be pleasantly surprised by my handiwork. ■

Katja Bargum is a graduate student in the Department of Biological andEnvironmental Sciences at the University of Helsinki, Finland.

Since I graduated in 2003 with abachelor’s in biology, my professionallife has been an on-again, off-againdrama. Should I move to a graduateprogramme straight away? Or should Itest the waters outside of the hallowedhalls of academia? I chose the latter.

I'm glad I did. I had little wind left inmy jib after four tough years. Thechallenge has been to remain active and keep my mind astute in the ever-changing fields of biology and ecology.Small, volunteer gigs and journal-reading sufficed for a while, but I soonbecame more aggressive in applying forfull-time positions.

I first targeted biology departmentsand also sought private-sector andfederal positions. Many opportunities Isaw were for full-time volunteers, mostrequiring major expense and lasting ashort time. Then in early 2005 I spotteda volunteer post at the PrimateHabituation Programme at the Dzanga-Ndoki National Park in the CentralAfrican Republic. I had never been thereand had never worked with primates.With a one-year commitment, Iwouldn’t feel like a tourist. I applied, gotthe position and was soon on my way.

The goal of the programme, based at a camp called Bai Hokou, is toacclimatize western lowland gorillasand semi-terrestrial mangabeys to the

presence of humans. An eco-tourismprogramme was set up with the backingof the government, the conservationcharity WWF and the German aidagency GTZ. The revenue is placed in a programme for local communities.Tourists have been visiting since 2001,although acclimatization efforts arelabour-intensive and ongoing.

The position enabled me to witness anew model of wildlife conservation thathad to weather poachers and limitedgovernment supervision. It was a starkcontrast to the carefully choreographedefforts I’d seen in the United States.

Because I was either fixing fuses,cooking over a wood fire or followinggorillas, I gave little thought to whatwould come next. So, since cominghome, I’m once again excruciatinglyover-analysing my career options.

I now plan to capitalize on thediscipline and intellectual stimulation I gained in the Congo basin by pursuing a master’s degree inevolutionary biology with an emphasis on conservation. In the mean time, I’m doing publicpresentations about working with wild animals in an effort to raiseawareness of conservation issues. ■

Ayres Christ is currently splittingtime between Washington DC andTennessee.

A recurring theme of Paul Gilna’s career has been to servethe scientific community while working at the cutting edgeof computational biology. His work to set up computationaltools and annotated genetic-sequence databases, such asGenBank, has aided the research of countless scientists.

After earning a degree in pharmacology at UniversityCollege Dublin, Gilna pursued a PhD focused on the drugsaffecting the hormones oestrogen and progesterone.Advised by mentors to enter the new world of molecularbiology, he serendipitously met molecular biologist PierreChambon. Gilna’s collaboration with Chambon’s group and colleagues at the University of Chicago in Illinoisculminated in the cloning and sequencing of humanoestrogen and progesterone receptors.

While a postdoc at Chicago, Gilna published papers thatwould become the basis of current genetic testing for thepredisposition to breast cancer. At this point, however, heopted out of research to use the computational-biologyskills he had taught himself. A position at GenBank, theannotated collection of publicly available gene sequencesat Los Alamos National Laboratory, met his goals. “I waslooking for something more tangible as evidence that whatI doing was of assistance to others,” he says.

Gilna constructed the now familiar requirement thatauthors of journal articles submit gene sequences toGenBank in exchange for an accession number printed withthe article. The procedure made digital data available toresearchers and streamlined the process of lifting printeddata from journals. He was co-principal investigator untilGenBank moved to the National Institutes of Health.

After two years at the National Science Foundation, Gilnareturned to Los Alamos to oversee the human-genomesequencing arm of the Department of Energy’s JointGenome Institute. One of his best achievements, he says,was aiding its transition to microbial genome sequencing.

His new role is executive director of the CAMERAproject, which provides computational and data-analysistools to decipher the collective genetic codes obtainedfrom as-yet unculturable ocean microbes. The partnershipbetween the J. Craig Venter Institute at the University ofCalifornia, San Diego, and the San Diego SupercomputerCenter will test his ability to lead disparate groups. “Thechallenge is not only that this is a new partnership, but thatit is creating the new field of metagenomics,” he says. ■

Virginia Gewin

MOVERS Paul Gilna, executive director, Community Cyber-infrastructure for Advanced Marine MicrobialEcology Research and Analysis (CAMERA)project, San Diego, California

2001–06: Director/manager,Center for Human GenomeStudies, Los Alamos NationalLaboratory (LANL), New Mexico1998–2000: Programmedirector, computation biologyand database activityprogrammes, National ScienceFoundation, Washington DC1994–98: Programme manager,biology and environmentalresearch, LANL, New Mexico

Lessons from the jungle

22.6 Jobs Career View MH 16/6/06 5:22 PM Page 1024

Nature Publishing Group ©2006