Lecture Notes in Computer Science 12263

Founding Editors

Gerhard GoosKarlsruhe Institute of Technology, Karlsruhe, Germany

Juris HartmanisCornell University, Ithaca, NY, USA

Editorial Board Members

Elisa BertinoPurdue University, West Lafayette, IN, USA

Wen GaoPeking University, Beijing, China

Bernhard SteffenTU Dortmund University, Dortmund, Germany

Gerhard WoegingerRWTH Aachen, Aachen, Germany

Moti YungColumbia University, New York, NY, USA

More information about this series at http://www.springer.com/series/7412

Anne L. Martel • Purang Abolmaesumi •

Danail Stoyanov • Diana Mateus •

Maria A. Zuluaga • S. Kevin Zhou •

Daniel Racoceanu • Leo Joskowicz (Eds.)

Medical Image Computingand Computer AssistedIntervention – MICCAI 202023rd International ConferenceLima, Peru, October 4–8, 2020Proceedings, Part III

123

EditorsAnne L. MartelUniversity of TorontoToronto, ON, Canada

Purang AbolmaesumiThe University of British ColumbiaVancouver, BC, Canada

Danail StoyanovUniversity College LondonLondon, UK

Diana MateusÉcole Centrale de NantesNantes, France

Maria A. ZuluagaEURECOMBiot, France

S. Kevin ZhouChinese Academy of SciencesBeijing, China

Daniel RacoceanuSorbonne UniversityParis, France

Leo JoskowiczThe Hebrew University of JerusalemJerusalem, Israel

ISSN 0302-9743 ISSN 1611-3349 (electronic)Lecture Notes in Computer ScienceISBN 978-3-030-59715-3 ISBN 978-3-030-59716-0 (eBook)https://doi.org/10.1007/978-3-030-59716-0

LNCS Sublibrary: SL6 – Image Processing, Computer Vision, Pattern Recognition, and Graphics

© Springer Nature Switzerland AG 2020This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of thematerial is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation,broadcasting, reproduction on microfilms or in any other physical way, and transmission or informationstorage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology nowknown or hereafter developed.The use of general descriptive names, registered names, trademarks, service marks, etc. in this publicationdoes not imply, even in the absence of a specific statement, that such names are exempt from the relevantprotective laws and regulations and therefore free for general use.The publisher, the authors and the editors are safe to assume that the advice and information in this book arebelieved to be true and accurate at the date of publication. Neither the publisher nor the authors or the editorsgive a warranty, expressed or implied, with respect to the material contained herein or for any errors oromissions that may have been made. The publisher remains neutral with regard to jurisdictional claims inpublished maps and institutional affiliations.

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Preface

The 23rd International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI 2020) was held this year under the most unusualcircumstances, due to the COVID-19 pandemic disrupting our lives in ways that wereunimaginable at the start of the new decade. MICCAI 2020 was scheduled to be held inLima, Peru, and would have been the first MICCAI meeting in Latin America.However, with the pandemic, the conference and its program had to be redesigned todeal with realities of the “new normal”, where virtual presence rather than physicalinteractions among attendees, was necessary to comply with global transmissioncontrol measures. The conference was held through a virtual conference managementplatform, consisting of the main scientific program in addition to featuring 25 work-shops, 8 tutorials, and 24 challenges during October 4–8, 2020. In order to keep a partof the original spirit of MICCAI 2020, SIPAIM 2020 was held as an adjacent LatAmconference dedicated to medical information management and imaging, held duringOctober 3–4, 2020.

The proceedings of MICCAI 2020 showcase papers contributed by the authors tothe main conference, which are organized in seven volumes of Lecture Notes inComputer Science (LNCS) books. These papers were selected after a thorough double-blind peer-review process. We followed the example set by past MICCAI meetings,using Microsoft’s Conference Managing Toolkit (CMT) for paper submission and peerreviews, with support from the Toronto Paper Matching System (TPMS) to partiallyautomate paper assignment to area chairs and reviewers.

The conference submission deadline had to be extended by two weeks to account forthe disruption COVID-19 caused on the worldwide scientific community. From 2,953original intentions to submit, 1,876 full submissions were received, which werereduced to 1,809 submissions following an initial quality check by the program chairs.Of those, 61% were self-declared by authors as Medical Image Computing (MIC), 6%as Computer Assisted Intervention (CAI), and 32% as both MIC and CAI. Following abroad call to the community for self-nomination of volunteers and a thorough reviewby the program chairs, considering criteria such as balance across research areas,geographical distribution, and gender, the MICCAI 2020 Program Committee com-prised 82 area chairs, with 46% from North America, 28% from Europe, 19% fromAsia/Pacific/Middle East, 4% from Latin America, and 1% from Australia. We investedsignificant effort in recruiting more women to the Program Committee, following theconference’s emphasis on equity, inclusion, and diversity. This resulted in 26% femalearea chairs. Each area chair was assigned about 23 manuscripts, with suggestedpotential reviewers using TPMS scoring and self-declared research areas, while domainconflicts were automatically considered by CMT. Following a final revision and pri-oritization of reviewers by area chairs in terms of their expertise related to each paper,

over 1,426 invited reviewers were asked to bid for the papers for which they had beensuggested. Final reviewer allocations via CMT took account of reviewer bidding,prioritization of area chairs, and TPMS scores, leading to allocating about 4 papers perreviewer. Following an initial double-blind review phase by reviewers, area chairsprovided a meta-review summarizing key points of reviews and a recommendation foreach paper. The program chairs then evaluated the reviews and their scores, along withthe recommendation from the area chairs, to directly accept 241 papers (13%) andreject 828 papers (46%); the remainder of the papers were sent for rebuttal by theauthors. During the rebuttal phase, two additional area chairs were assigned to eachpaper using the CMT and TPMS scores while accounting for domain conflicts. Thethree area chairs then independently scored each paper to accept or reject, based on thereviews, rebuttal, and manuscript, resulting in clear paper decisions using majorityvoting. This process resulted in the acceptance of a further 301 papers for an overallacceptance rate of 30%. A virtual Program Committee meeting was held on July 10,2020, to confirm the final results and collect feedback of the peer-review process.

For the MICCAI 2020 proceedings, 542 accepted papers have been organized intoseven volumes as follows:

• Part I, LNCS Volume 12261: Machine Learning Methodologies• Part II, LNCS Volume 12262: Image Reconstruction and Machine Learning• Part III, LNCS Volume 12263: Computer Aided Intervention, Ultrasound and

Image Registration• Part IV, LNCS Volume 12264: Segmentation and Shape Analysis• Part V, LNCS Volume 12265: Biological, Optical and Microscopic Image Analysis• Part VI, LNCS Volume 12266: Clinical Applications• Part VII, LNCS Volume 12267: Neurological Imaging and PET

For the main conference, the traditional emphasis on poster presentations wasmaintained; each author uploaded a brief pre-recorded presentation and a graphicalabstract onto a web platform and was allocated a personal virtual live session in whichthey talked directly to the attendees. It was also possible to post questions onlineallowing asynchronous conversations – essential to overcome the challenges of a globalconference spanning many time zones. The traditional oral sessions, which typicallyincluded a small proportion of the papers, were replaced with 90 “mini” sessions whereall of the authors were clustered into groups of 5 to 7 related papers; a live virtualsession allowed the authors and attendees to discuss the papers in a panel format.

We would like to sincerely thank everyone who contributed to the success ofMICCAI 2020 and the quality of its proceedings under the most unusual circumstancesof a global pandemic. First and foremost, we thank all authors for submitting andpresenting their high-quality work that made MICCAI 2020 a greatly enjoyable andsuccessful scientific meeting. We are also especially grateful to all members of theProgram Committee and reviewers for their dedicated effort and insightful feedbackthroughout the entire paper selection process. We would like to particularly thank theMICCAI society for support, insightful comments, and continuous engagement withorganizing the conference. Special thanks go to Kitty Wong, who oversaw the entire

vi Preface

process of paper submission, reviews, and preparation of conference proceedings.Without her, we would have not functioned effectively. Given the “new normal”, noneof the workshops, tutorials, and challenges would have been feasible without the trueleadership of the satellite events organizing team led by Mauricio Reyes: ErikMeijering (workshops), Carlos Alberola-López (tutorials), and Lena Maier-Hein(challenges). Behind the scenes, MICCAI secretarial personnel, Janette Wallace andJohanne Langford, kept a close eye on logistics and budgets, while Mehmet Eldegezand his team at Dekon Congress and Tourism led the professional conference orga-nization, working tightly with the virtual platform team. We also thank our sponsors forfinancial support and engagement with conference attendees through the virtual plat-form. Special thanks goes to Veronika Cheplygina for continuous engagement withvarious social media platforms before and throughout the conference to publicize theconference. We would also like to express our gratitude to Shelley Wallace for helpingus in Marketing MICCAI 2020, especially during the last phase of the virtual con-ference organization.

The selection process for Young Investigator Awards was managed by a team ofsenior MICCAI investigators, led by Julia Schnabel. In addition, MICCAI 2020 offeredfree registration to the top 50 ranked papers at the conference whose primary authorswere students. Priority was given to low-income regions and Latin American students.Further support was provided by the National Institutes of Health (support granted forMICCAI 2020) and the National Science Foundation (support granted to MICCAI2019 and continued for MICCAI 2020) which sponsored another 52 awards for USA-based students to attend the conference. We would like to thank Marius Linguraru andAntonion Porras, for their leadership in regards to the NIH sponsorship for 2020, andDinggang Shen and Tianming Liu, MICCAI 2019 general chairs, for keeping an activebridge and engagement with MICCAI 2020.

Marius Linguraru and Antonion Porras were also leading the young investigatorsearly career development program, including a very active mentorship which we dohope, will significantly catalize young and briliant careers of future leaders of ourscientific community. In link with SIPAIM (thanks to Jorge Brieva, Marius Linguraru,and Natasha Lepore for their support), we also initiated a Startup Village initiative,which, we hope, will be able to bring in promissing private initiatives in the areas ofMICCAI. As a part of SIPAIM 2020, we note also the presence of a workshop forPeruvian clinicians. We would like to thank Benjaming Castañeda and Renato Gandolfifor this initiative.

MICCAI 2020 invested significant efforts to tightly engage the industry stakeholdersin our field throughout its planning and organization. These efforts were led by ParvinMousavi, and ensured that all sponsoring industry partners could connect with theconference attendees through the conference’s virtual platform before and during themeeting. We would like to thank the sponsorship team and the contributions

Preface vii

of Gustavo Carneiro, Benjamín Castañeda, Ignacio Larrabide, Marius Linguraru,Yanwu Xu, and Kevin Zhou.

We look forward to seeing you at MICCAI 2021.

October 2020 Anne L. MartelPurang Abolmaesumi

Danail StoyanovDiana Mateus

Maria A. ZuluagaS. Kevin Zhou

Daniel RacoceanuLeo Joskowicz

viii Preface

Organization

General Chairs

Daniel Racoceanu Sorbonne Université, Brain Institute, FranceLeo Joskowicz The Hebrew University of Jerusalem, Israel

Program Committee Chairs

Anne L. Martel University of Toronto, CanadaPurang Abolmaesumi The University of British Columbia, CanadaDanail Stoyanov University College London, UKDiana Mateus Ecole Centrale de Nantes, LS2N, FranceMaria A. Zuluaga Eurecom, FranceS. Kevin Zhou Chinese Academy of Sciences, China

Keynote Speaker Chair

Rene Vidal The John Hopkins University, USA

Satellite Events Chair

Mauricio Reyes University of Bern, Switzerland

Workshop Team

Erik Meijering (Chair) The University of New South Wales, AustraliaLi Cheng University of Alberta, CanadaPamela Guevara University of Concepción, ChileBennett Landman Vanderbilt University, USATammy Riklin Raviv Ben-Gurion University of the Negev, IsraelVirginie Uhlmann EMBL, European Bioinformatics Institute, UK

Tutorial Team

Carlos Alberola-López(Chair)

Universidad de Valladolid, Spain

Clarisa Sánchez Radboud University Medical Center, The NetherlandsDemian Wassermann Inria Saclay Île-de-France, France

Challenges Team

Lena Maier-Hein (Chair) German Cancer Research Center, GermanyAnnette Kopp-Schneider German Cancer Research Center, GermanyMichal Kozubek Masaryk University, Czech RepublicAnnika Reinke German Cancer Research Center, Germany

Sponsorship Team

Parvin Mousavi (Chair) Queen’s University, CanadaMarius Linguraru Children’s National Institute, USAGustavo Carneiro The University of Adelaide, AustraliaYanwu Xu Baidu Inc., ChinaIgnacio Larrabide National Scientific and Technical Research Council,

ArgentinaS. Kevin Zhou Chinese Academy of Sciences, ChinaBenjamín Castañeda Pontifical Catholic University of Peru, Peru

Local and Regional Chairs

Benjamín Castañeda Pontifical Catholic University of Peru, PeruNatasha Lepore University of Southern California, USA

Social Media Chair

Veronika Cheplygina Eindhoven University of Technology, The Netherlands

Young Investigators Early Career Development Program Chairs

Marius Linguraru Children’s National Institute, USAAntonio Porras Children’s National Institute, USA

Student Board Liaison Chair

Gabriel Jimenez Pontifical Catholic University of Peru, Peru

Submission Platform Manager

Kitty Wong The MICCAI Society, Canada

Conference Management

DEKON GroupPathable Inc.

x Organization

Program Committee

Ehsan Adeli Stanford University, USAShadi Albarqouni ETH Zurich, SwitzerlandPablo Arbelaez Universidad de los Andes, ColombiaUlas Bagci University of Central Florida, USAAdrien Bartoli Université Clermont Auvergne, FranceHrvoje Bogunovic Medical University of Vienna, AustriaWeidong Cai The University of Sydney, AustraliaChao Chen Stony Brook University, USAElvis Chen Robarts Research Institute, CanadaStanley Durrleman Inria, FranceBoris Escalante-Ramírez National Autonomous University of Mexico, MexicoPascal Fallavollita University of Ottawa, CanadaEnzo Ferrante CONICET, Universidad Nacional del Litoral,

ArgentinaStamatia Giannarou Imperial College London, UKOrcun Goksel ETH Zurich, SwitzerlandAlberto Gomez King’s College London, UKMiguel Angel González

BallesterUniversitat Pompeu Fabra, Spain

Ilker Hacihaliloglu Rutgers University, USAYi Hong University of Georgia, USAYipeng Hu University College London, UKHeng Huang University of Pittsburgh and JD Finance America

Corporation, USAJuan Eugenio Iglesias University College London, UKMadhura Ingalhalikar Symbiosis Center for Medical Image Analysis, IndiaPierre Jannin Université de Rennes, FranceSamuel Kadoury Ecole Polytechnique de Montreal, CanadaBernhard Kainz Imperial College London, UKMarta Kersten-Oertel Concordia University, CanadaAndrew King King’s College London, UKIgnacio Larrabide CONICET, ArgentinaGang Li University of North Carolina at Chapel Hill, USAJianming Liang Arizona State University, USAHongen Liao Tsinghua University, ChinaRui Liao Siemens Healthineers, USAFeng Lin Nanyang Technological University, ChinaMingxia Liu University of North Carolina at Chapel Hill, USAJiebo Luo University of Rochester, USAXiongbiao Luo Xiamen University, ChinaAndreas Maier FAU Erlangen-Nuremberg, GermanyStephen McKenna University of Dundee, UKBjoern Menze Technische Universität München, GermanyMehdi Moradi IBM Research, USA

Organization xi

Dong Ni Shenzhen University, ChinaMarc Niethammer University of North Carolina at Chapel Hill, USAJack Noble Vanderbilt University, USAIpek Oguz Vanderbilt University, USAGemma Piella Pompeu Fabra University, SpainHedyeh Rafii-Tari Auris Health Inc., USAIslem Rekik Istanbul Technical University, TurkeyNicola Rieke NVIDIA Corporation, USATammy Riklin Raviv Ben-Gurion University of the Negev, IsraelHassan Rivaz Concordia University, CanadaHolger Roth NVIDIA Corporation, USASharmishtaa Seshamani Allen Institute, USALi Shen University of Pennsylvania, USAFeng Shi Shanghai United Imaging Intelligence Co., ChinaYonggang Shi University of Southern California, USAMichal Sofka Hyperfine Research, USAStefanie Speidel National Center for Tumor Diseases (NCT), GermanyMarius Staring Leiden University Medical Center, The NetherlandsHeung-Il Suk Korea University, South KoreaKenji Suzuki Tokyo Institute of Technology, JapanTanveer Syeda-Mahmood IBM Research, USAAmir Tahmasebi CodaMetrix, USAXiaoying Tang Southern University of Science and Technology, ChinaTolga Tasdizen The University of Utah, USAPallavi Tiwari Case Western Reserve University, USASotirios Tsaftaris The University of Edinburgh, UKArchana Venkataraman Johns Hopkins University, USASatish Viswanath Case Western Reserve University, USAHongzhi Wang IBM Almaden Research Center, USALinwei Wang Rochester Institute of Technology, USAQian Wang Shanghai Jiao Tong University, ChinaGuorong Wu University of North Carolina at Chapel Hill, USADaguang Xu NVIDIA Corporation, USAZiyue Xu NVIDIA Corporation, USAPingkun Yan Rensselaer Polytechnic Institute, USAXin Yang Huazhong University of Science and Technology,

ChinaZhaozheng Yin Stony Brook University, USATuo Zhang Northwestern Polytechnical University, ChinaGuoyan Zheng Shanghai Jiao Tong University, ChinaYefeng Zheng Tencent, ChinaLuping Zhou The University of Sydney, Australia

xii Organization

Mentorship Program (Mentors)

Ehsan Adeli Stanford University, USAStephen Aylward Kitware, USAHrvoje Bogunovic Medical University of Vienna, AustriaLi Cheng University of Alberta, CanadaMarleen de Bruijne University of Copenhagen, DenmarkCaroline Essert University of Strasbourg, FranceGabor Fichtinger Queen’s University, CanadaStamatia Giannarou Imperial College London, UKJuan Eugenio Iglesias

GonzalezUniversity College London, UK

Bernhard Kainz Imperial College London, UKShuo Li Western University, CanadaJianming Liang Arizona State University, USARui Liao Siemens Healthineers, USAFeng Lin Nanyang Technological University, ChinaMarius George Linguraru Children’s National Hospital, George Washington

University, USATianming Liu University of Georgia, USAXiongbiao Luo Xiamen University, ChinaDong Ni Shenzhen University, ChinaWiro Niessen Erasmus MC - University Medical Center Rotterdam,

The NetherlandsTerry Peters Western University, CanadaAntonio R. Porras University of Colorado, USADaniel Racoceanu Sorbonne University, FranceIslem Rekik Istanbul Technical University, TurkeyNicola Rieke NVIDIA, USAJulia Schnabel King’s College London, UKRuby Shamir Novocure, SwitzerlandStefanie Speidel National Center for Tumor Diseases Dresden, GermanyMartin Styner University of North Carolina at Chapel Hill, USAXiaoying Tang Southern University of Science and Technology, ChinaPallavi Tiwari Case Western Reserve University, USAJocelyne Troccaz CNRS, Grenoble Alpes University, FrancePierre Jannin INSERM, Université de Rennes, FranceArchana Venkataraman Johns Hopkins University, USALinwei Wang Rochester Institute of Technology, USAGuorong Wu University of North Carolina at Chapel Hill, USALi Xiao Chinese Academy of Science, ChinaZiyue Xu NVIDIA, USABochuan Zheng China West Normal University, ChinaGuoyan Zheng Shanghai Jiao Tong University, ChinaS. Kevin Zhou Chinese Academy of Sciences, ChinaMaria A. Zuluaga EURECOM, France

Organization xiii

Additional Reviewers

Alaa Eldin AbdelaalAhmed AbdulkadirClement Abi NaderMazdak AbulnagaGanesh AdluruIman AganjPriya AggarwalSahar AhmadSeyed-Ahmad AhmadiEuijoon AhnAlireza Akhondi-aslMohamed AkroutDawood Al ChantiIbraheem Al-DhamariNavid Alemi KoohbananiHanan AlghamdiHassan AlhajjHazrat AliSharib AliOmar Al-KadiMaximilian AllanFelix AmbellanMina AmiriSameer AntaniLuigi AntelmiMichela AntonelliJacob AntunesSaeed AnwarFernando ArambulaIgnacio Arganda-CarrerasMohammad Ali ArminJohn AshburnerMd AshikuzzamanShahab AslaniMehdi AstarakiAngélica AtehortúaGowtham AtluriKamran AvanakiAngelica Aviles-RiveroSuyash AwateDogu Baran AydoganQinle BaMorteza Babaie

Hyeon-Min BaeWoong BaeWenjia BaiUjjwal BaidSpyridon BakasYaël BalbastreMarcin BalickiFabian BalsigerAbhirup BanerjeeSreya BanerjeeSophia BanoShunxing BaoAdrian BarbuCher BassJohn S. H. BaxterAmirhossein BayatSharareh BayatNeslihan BayramogluBahareh BehboodiDelaram BehnamiMikhail BelyaevOualid BenkarimAicha BenTaiebCamilo BermudezGiulia BertòHadrien BertrandJulián BetancurMichael BeyelerParmeet BhatiaChetan BholeSuvrat BhooshanChitresh BhushanLei BiCheng BianGui-Bin BianSangeeta BiswasStefano B. BlumbergJanusz BobulskiSebastian BodenstedtEster BonmatiBhushan BorotikarJiri BorovecIlaria Boscolo Galazzo

xiv Organization

Alexandre BousseNicolas BoutryBehzad BozorgtabarNadia BrancatiChristopher BridgeEsther BronRupert BrooksQirong BuTim-Oliver BuchholzDuc Toan BuiQasim BukhariNinon BurgosNikolay BurlutskiyRussell ButlerMichał ByraHongmin CaiYunliang CaiSema CandemirBing CaoQing CaoShilei CaoTian CaoWeiguo CaoYankun CaoAaron CarassHeike CarolusAdrià CasamitjanaSuheyla Cetin KarayumakAhmad ChaddadKrishna ChaitanyaJayasree ChakrabortyTapabrata ChakrabortySylvie ChambonMing-Ching ChangVioleta ChangSimon ChatelinSudhanya ChatterjeeChristos ChatzichristosRizwan ChaudhryAntong ChenCameron Po-Hsuan ChenChang ChenChao ChenChen ChenCheng ChenDongdong Chen

Fang ChenGeng ChenHao ChenJianan ChenJianxu ChenJia-Wei ChenJie ChenJunxiang ChenLi ChenLiang ChenPingjun ChenQiang ChenShuai ChenTianhua ChenTingting ChenXi ChenXiaoran ChenXin ChenYuanyuan ChenYuhua ChenYukun ChenZhineng ChenZhixiang ChenErkang ChengJun ChengLi ChengXuelian ChengYuan ChengVeronika CheplyginaHyungjoo ChoJaegul ChooAritra ChowdhuryStergios ChristodoulidisAi Wern ChungPietro Antonio CicaleseÖzgün ÇiçekRobert CierniakMatthew ClarksonDana CobzasJaume Coll-FontAlessia ColonnaMarc CombaliaOlivier CommowickSonia Contreras OrtizPierre-Henri ConzeTimothy Cootes

Organization xv

Luca CorinziaTeresa CorreiaPierrick CoupéJeffrey CraleyArun C. S. KumarHui CuiJianan CuiZhiming CuiKathleen CurranHaixing DaiXiaoliang DaiKer Dai Fei ElmerAdrian DalcaAbhijit DasNeda DavoudiLaura DazaSandro De ZanetCharles DelahuntHerve DelingetteBeatrice DemirayYang DengHrishikesh DeshpandeChristian DesrosiersNeel DeyXinghao DingZhipeng DingKonstantin DmitrievJose DolzInes DominguesJuan Pedro Dominguez-MoralesHao DongMengjin DongNanqing DongQinglin DongSuyu DongSven DorkenwaldQi DouP. K. DouglasSimon DrouinKaren DrukkerNiharika D’SouzaLei DuShaoyi DuXuefeng DuDingna DuanNicolas Duchateau

James DuncanJared DunnmonLuc DuongNicha DvornekDmitry V. DylovOleh DzyubachykMehran EbrahimiPhilip EdwardsAlexander EfflandJan EggerAlma EguizabalGudmundur EinarssonAhmed ElazabMohammed S. M. ElbazShireen ElhabianAhmed EltanbolySandy EngelhardtErtunc ErdilMarius ErdtFloris ErnstMohammad EslamiNazila EsmaeiliMarco EspositoOscar EstebanJingfan FanXin FanYonghui FanChaowei FangXi FangMohsen FarziJohannes FauserAndrey FedorovHamid FehriLina FelsnerJun FengRuibin FengXinyang FengYifan FengYuan FengHenrique FernandesRicardo FerrariJean FeydyLucas FidonLukas FischerAntonio Foncubierta-RodríguezGermain Forestier

xvi Organization

Reza ForghaniNils Daniel ForkertJean-Rassaire FouefackTatiana FountoukidouAina Frau-PascualMoti FreimanSarah FriskenHuazhu FuXueyang FuWolfgang FuhlIsabel FunkePhilipp FürnstahlPedro FurtadoRyo FurukawaElies Fuster-GarciaYoussef GahiJin Kyu GahmLaurent GajnyRohan GalaHarshala GammulleYu GanCong GaoDongxu GaoFei GaoFeng GaoLinlin GaoMingchen GaoSiyuan GaoXin GaoXinpei GaoYixin GaoYue GaoZhifan GaoSara GarbarinoAlfonso Gastelum-StrozziRomane GauriauSrishti GautamBao GeRongjun GeZongyuan GeSairam GeethanathYasmeen GeorgeSamuel GerberGuido GerigNils GessertOlivier Gevaert

Muhammad Usman GhaniSandesh GhimireSayan GhosalGabriel GirardBen GlockerEvgin GoceriMichael GoetzArnold GomezKuang GongMingming GongYuanhao GongGerman GonzalezSharath GopalKarthik GopinathPietro GoriMaged GoubranSobhan GoudarziBaran GözcüBenedikt GrafMark GrahamBertrand GranadoAlejandro GranadosRobert GruppChristina GsaxnerLin GuShi GuYun GuRicardo GuerreroHoussem-Eddine GueziriDazhou GuoHengtao GuoJixiang GuoPengfei GuoYanrong GuoYi GuoYong GuoYulan GuoYuyu GuoKrati GuptaVikash GuptaPraveen Gurunath BharathiPrashnna GyawaliStathis HadjidemetriouOmid Haji MaghsoudiJustin HaldarMohammad Hamghalam

Organization xvii

Bing HanHu HanLiang HanXiaoguang HanXu HanZhi HanZhongyi HanJonny HancoxChristian HansenXiaoke HaoRabia HaqMichael HardistyStefan HarrerAdam HarrisonS. M. Kamrul HasanHoda Sadat HashemiNobuhiko HataAndreas HauptmannMohammad HavaeiHuiguang HeJunjun HeKelei HeTiancheng HeXuming HeYuting HeMattias HeinrichStefan HeldmannNicholas HellerAlessa HeringMonica HernandezEstefania Hernandez-MartinCarlos Hernandez-MatasJavier Herrera-VegaKilian HettTsung-Ying HoNico HoffmannMatthew HoldenSong HongSungmin HongYoonmi HongCorné HoogendoornAntal HorváthBelayat HossainLe HouAi-Ling HsuPo-Ya Hsu

Tai-Chiu HsungPengwei HuShunbo HuXiaoling HuXiaowei HuYan HuZhenhong HuJia-Hong HuangJunzhou HuangKevin HuangQiaoying HuangWeilin HuangXiaolei HuangYawen HuangYongxiang HuangYue HuangYufang HuangZhi HuangArnaud HuaulméHenkjan HuismanXing HuoYuankai HuoSarfaraz HusseinJana HutterKhoi HuynhSeong Jae HwangEmmanuel IarussiIlknur IckeKay IgweAlfredo IllanesAbdullah-Al-Zubaer ImranIsmail IrmakciSamra IrshadBenjamin IrvingMobarakol IslamMohammad Shafkat IslamVamsi IthapuKoichi ItoHayato ItohOleksandra IvashchenkoYuji IwahoriShruti JadonMohammad JafariMostafa JahanifarAndras JakabAmir Jamaludin

xviii Organization

Won-Dong JangVincent JaouenUditha JarayathneRonnachai JaroensriGolara JavadiRohit JenaTodd JensenWon-Ki JeongZexuan JiHaozhe JiaJue JiangTingting JiangWeixiong JiangXi JiangXiang JiangJianbo JiaoZhicheng JiaoAmelia Jiménez-SánchezDakai JinTaisong JinYueming JinZe JinBin JingYaqub JonmohamadiAnand JoshiShantanu JoshiChristoph JudFlorian JugYohan JunAlain JungoAbdolrahim KadkhodamohammadiAli Kafaei Zad TehraniDagmar KainmuellerSiva Teja KakiletiJohn KalafutKonstantinos KamnitsasMichael C. KampffmeyerQingbo KangNeerav KaraniDavood KarimiSatyananda KashyapAlexander KatzmannPrabhjot KaurAnees KaziErwan KerrienHoel Kervadec

Ashkan KhakzarFahmi KhalifaNadieh KhaliliSiavash KhallaghiFarzad KhalvatiHassan KhanBishesh KhanalPulkit KhandelwalMaksym KholiavchenkoMeenakshi KhoslaNaji KhosravanSeyed Mostafa KiaRon KikinisDaeseung KimGeena KimHak Gu KimHeejong KimHosung KimHyo-Eun KimJinman KimJinyoung KimMansu KimMinjeong KimSeong Tae KimWon Hwa KimYoung-Ho KimAtilla KiralyYoshiro KitamuraTakayuki KitasakaSabrina KletzTobias KlinderKranthi KolliSatoshi KondoBin KongJun KongTomasz KonopczynskiEnder KonukogluBongjin KooKivanc KoseAnna KreshukAnithaPriya KrishnanPavitra KrishnaswamyFrithjof KruggelAlexander KrullElizabeth KrupinskiHulin Kuang

Organization xix

Serife KucurDavid KüglerArjan KuijperJan KukackaNilima KulkarniAbhay KumarAshnil KumarKuldeep KumarNeeraj KumarNitin KumarManuela KunzHolger KunzeTahsin KurcThomas KurmannYoshihiro KurodaJin Tae KwakYongchan KwonAymen LaadhariDmitrii LachinovAlexander LadikosAlain LalandeRodney LalondeTryphon LambrouHengrong LanCatherine LaporteCarole LartizienBianca Lassen-SchmidtAndras LassoNgan LeLeo LebratChanghwan LeeEung-Joo LeeHyekyoung LeeJong-Hwan LeeJungbeom LeeMatthew LeeSangmin LeeSoochahn LeeStefan LegerÉtienne LégerBaiying LeiAndreas LeibetsederRogers Jeffrey Leo JohnJuan LeonWee Kheng LeowAnnan Li

Bo LiChongyi LiHaohan LiHongming LiHongwei LiHuiqi LiJian LiJianning LiJiayun LiJunhua LiLincan LiMengzhang LiMing LiQing LiQuanzheng LiShulong LiShuyu LiWeikai LiWenyuan LiXiang LiXiaomeng LiXiaoxiao LiXin LiXiuli LiYang Li (Beihang University)Yang Li (Northeast Electric Power

University)Yi LiYuexiang LiZeju LiZhang LiZhen LiZhiyuan LiZhjin LiZhongyu LiChunfeng LianGongbo LiangLibin LiangShanshan LiangYudong LiangHaofu LiaoRuizhi LiaoGilbert LimBaihan LinHongxiang LinHuei-Yung Lin

xx Organization

Jianyu LinC. LindnerGeert LitjensBin LiuChang LiuDongnan LiuFeng LiuHangfan LiuJianfei LiuJin LiuJingya LiuJingyu LiuKai LiuKefei LiuLihao LiuLuyan LiuMengting LiuNa LiuPeng LiuPing LiuQuande LiuQun LiuShengfeng LiuShuangjun LiuSidong LiuSiqi LiuSiyuan LiuTianrui LiuXianglong LiuXinyang LiuYan LiuYuan LiuYuhang LiuAndrea LoddoHerve LombaertMarco LorenziJian LouNicolas Loy RodasAllen LuDonghuan LuHuanxiang LuJiwen LuLe LuWeijia LuXiankai LuYao Lu

Yongyi LuYueh-Hsun LuChristian LucasOeslle LucenaImanol LuengoRonald LuiGongning LuoJie LuoMa LuoMarcel LuthiKhoa LuuBin LvJinglei LvIlwoo LyuQing LyuSharath M. S.Andy J. MaChunwei MaDa MaHua MaJingting MaKai MaLei MaWenao MaYuexin MaAmirreza MahbodSara MahdaviMohammed MahmoudGabriel MaicasKlaus H. Maier-HeinSokratis MakrogiannisBilal MalikAnand MalpaniIlja ManakovMatteo ManciniEfthymios ManeasTommaso MansiBrett MarinelliRazvan MarinescuPablo Márquez NeilaCarsten MarrYassine MarrakchiFabio MartinezAntonio Martinez-TorteyaAndre MastmeyerDimitrios Mavroeidis

Organization xxi

Jamie McClellandVerónica Medina BañuelosRaghav MehtaSachin MehtaLiye MeiRaphael MeierQier MengQingjie MengYu MengMartin MentenOdyssée MerveillePablo MesejoLiang MiShun MiaoStijn MichielseMikhail MilchenkoHyun-Seok MinZhe MinTadashi MiyamotoAryan MobinyIrina MocanuSara MocciaOmid MohareriHassan Mohy-ud-DinMuthu Rama Krishnan MookiahRodrigo MorenoLia MorraAgata MosinskaSaman MotamedMohammad Hamed MozaffariAnirban MukhopadhyayHenning MüllerBalamurali MurugesanCosmas MwikirizeAndriy MyronenkoSaad NadeemAhmed NaglahVivek NatarajanVishwesh NathRodrigo NavaFernando NavarroLydia Neary-ZajiczekPeter NeherDominik NeumannGia NgoHannes Nickisch

Dong NieJingxin NieWeizhi NieAditya NigamXia NingZhenyuan NingSijie NiuTianye NiuAlexey NovikovJorge NovoChinedu NwoyeMohammad ObeidMasahiro OdaThomas O’DonnellBenjamin OdrySteffen Oeltze-JafraAyşe OktayHugo OliveiraMarcelo OliveiraSara OliveiraArnau OliverSahin OlutJimena OlveresJohn OnofreyEliza OrasanuFelipe Orihuela-EspinaJosé OrlandoMarcos OrtegaSarah OstadabbasYoshito OtakeSebastian OtaloraCheng OuyangJiahong OuyangCristina Oyarzun LauraMichal Ozery-FlatoKrittin PachtrachaiJohannes PaetzoldJin PanYongsheng PanPrashant PandeyJoao PapaGiorgos PapanastasiouConstantin PapeNripesh ParajuliHyunjin ParkSanghyun Park

xxii Organization

Seyoun ParkAngshuman PaulChristian PayerChengtao PengJialin PengLiying PengTingying PengYifan PengTobias PenzkoferAntonio PepeOscar PerdomoJose-Antonio Pérez-CarrascoFernando Pérez-GarcíaJorge Perez-GonzalezSkand PeriLoic PeterJorg PetersJens PetersenCaroline PetitjeanMicha PfeifferDzung PhamRenzo PhellanAshish PhophaliaMark PickeringKilian PohlIulia PopescuKarteek PopuriTiziano PortenierAlison PouchArash PourtaherianPrateek PrasannaAlexander PreuhsRaphael PrevostJuan PrietoViswanath P. S.Sergi PujadesKumaradevan PunithakumarElodie PuybareauHaikun QiHuan QiXin QiBuyue QianZhen QianYan QiangYuchuan QiaoZhi Qiao

Chen QinWenjian QinYanguo QinWu QiuHui QuKha Gia QuachPrashanth R.Pradeep Reddy RaamanaJagath RajapakseKashif RajpootJhonata RamosAndrik RampunParnesh RanigaNagulan RatnarajahRichard RauMehul RavalKeerthi Sravan RaviDaniele RavìHarish RaviPrakashRohith ReddyMarkus RempflerXuhua RenYinhao RenYudan RenAnne-Marie RickmannBrandalyn RiedelLeticia RittnerRobert RobinsonJessica RodgersRobert RohlingLukasz RoszkowiakKarsten RothJosé RoucoSu RuanDaniel RueckertMirabela RusuErica RutterJaime S. CardosoMohammad SabokrouMonjoy SahaPramit SahaDushyant SahooPranjal SahuWojciech SamekJuan A. Sánchez-MargalloRobin Sandkuehler

Organization xxiii

Rodrigo Santa CruzGianmarco SantiniAnil Kumar SaoMhd Hasan SarhanDuygu SarikayaImari SatoOlivier SautMattia SavardiRamasamy SavithaFabien ScalzoNico ScherfAlexander SchlaeferPhilipp SchleerLeopold SchmettererJulia SchnabelKlaus SchoeffmannPeter SchuefflerAndreas SchuhThomas SchultzMichael SchwierMichael SdikaSuman SedaiRaghavendra SelvanSourya SenguptaYoungho SeoLama SeoudAna SequeiraSaeed SeyyediGiorgos SfikasSobhan ShafieiReuben ShamirShayan ShamsHongming ShanYeqin ShaoHarshita SharmaGregory SharpMohamed ShehataHaocheng ShenMali ShenYiqiu ShenZhengyang ShenLuyao ShiXiaoshuang ShiYemin ShiYonghong ShiSaurabh Shigwan

Hoo-Chang ShinSuprosanna ShitYucheng ShuNadya ShusharinaAlberto SignoroniCarlos A. SilvaWilson SilvaPraveer SinghRamandeep SinghRohit SinglaSumedha SinglaAyushi SinhaRajath SoansHessam SokootiJaemin SonMing SongTianyu SongYang SongYouyi SongAristeidis SotirasArcot SowmyaRachel SparksBella SpecktorWilliam SpeierZiga SpiclinDominik SpinczykChetan SrinidhiVinkle SrivastavLawrence StaibPeter SteinbachDarko SternJoshua StoughJustin StraitRobin StrandMartin StynerHai SuPan SuYun-Hsuan SuVaishnavi SubramanianGérard SubsolCarole SudreYao SuiAvan SuinesiaputraJeremias SulamShipra SumanJian Sun

xxiv Organization

Liang SunTao SunKyung SungChiranjib SurYannick SuterRaphael SznitmanSolale TabarestaniFatemeh Taheri DezakiRoger TamJosé Tamez-PeñaChaowei TanJiaxing TanHao TangSheng TangThomas TangXiongfeng TangZhenyu TangMickael TardyEu Wern TehAntonio Tejero-de-PablosPaul ThienphrapaStephen ThompsonFelix ThomsenJiang TianYun TianAleksei TiulpinHamid TizhooshMatthew ToewsOguzhan TopsakalJordina TorrentsSylvie TreuilletJocelyne TroccazEmanuele TruccoVinh Truong HoangChialing TsaiAndru Putra TwinandaNorimichi UkitaEranga UkwattaMathias UnberathTamas UngiMartin UrschlerVerena UslarFatmatulzehra UsluRégis VaillantJeya Maria Jose ValanarasuMarta Vallejo

Fons van der SommenGijs van TulderKimberlin van WijnenYogatheesan VaratharajahMarta VarelaThomas VarsavskyFrancisco VasconcelosS. Swaroop VedulaSanketh VedulaHarini VeeraraghavanGonzalo Vegas Sanchez-FerreroAnant VemuriGopalkrishna VeniRuchika VermaUjjwal VermaPedro VieiraJuan Pedro Vigueras GuillenPierre-Frederic VillardAthanasios VlontzosWolf-Dieter VoglIngmar VoigtEugene VorontsovBo WangCheng WangChengjia WangChunliang WangDadong WangGuotai WangHaifeng WangHongkai WangHongyu WangHua WangHuan WangJun WangKuanquan WangKun WangLei WangLi WangLiansheng WangManning WangRuixuan WangShanshan WangShujun WangShuo WangTianchen WangTongxin Wang

Organization xxv

Wenzhe WangXi WangXiangxue WangYalin WangYan Wang (Sichuan University)Yan Wang (Johns Hopkins University)Yaping WangYi WangYirui WangYuanjun WangYun WangZeyi WangZhangyang WangSimon WarfieldJonathan WeberJürgen WeeseDonglai WeiDongming WeiZhen WeiMartin WeigertMichael WelsJunhao WenMatthias WilmsStefan WinzeckAdam WittekMarek WodzinskiJelmer WolterinkKen C. L. WongJonghye WooChongruo WuDijia WuJi WuJian Wu (Tsinghua University)Jian Wu (Zhejiang University)Jie Ying WuJunyan WuMinjie WuPengxiang WuXi WuXia WuXiyin WuYe WuYicheng WuYifan WuZhengwang WuTobias Wuerfl

Pengcheng XiJames XiaSiyu XiaYingda XiaYong XiaLei XiangDeqiang XiaoLi Xiao (Tulane University)Li Xiao (Chinese Academy of Science)Yuting XiaoHongtao XieJianyang XieLingxi XieLong XieXueqian XieYiting XieYuan XieYutong XieFangxu XingFuyong XingTao XiongChenchu XuHongming XuJiaofeng XuKele XuLisheng XuMin XuRui XuXiaowei XuYanwu XuYongchao XuZhenghua XuCheng XueJie XueWufeng XueYuan XueFaridah YahyaChenggang YanKe YanWeizheng YanYu YanYuguang YanZhennan YanChangchun YangChao-Han Huck YangDong Yang

xxvi Organization

Fan Yang (IIAI)Fan Yang (Temple University)Feng YangGe YangGuang YangHeran YangHongxu YangHuijuan YangJiancheng YangJie YangJunlin YangLin YangXiao YangXiaohui YangXin YangYan YangYujiu YangDongren YaoJianhua YaoJiawen YaoLi YaoChuyang YeHuihui YeMenglong YeXujiong YeAndy W. K. YeungJingru YiJirong YiXin YiYi YinShihui YingYoungjin YooChenyu YouSahar YousefiHanchao YuJinhua YuKai YuLequan YuQi YuYang YuZhen YuPengyu YuanYixuan YuanPaul YushkevichGhada ZamzmiDong Zeng

Guodong ZengOliver ZettinigZhiwei ZhaiKun ZhanBaochang ZhangChaoyi ZhangDaoqiang ZhangDongqing ZhangFan Zhang (Yale University)Fan Zhang (Harvard Medical School)Guangming ZhangHan ZhangHang ZhangHaopeng ZhangHeye ZhangHuahong ZhangJianpeng ZhangJinao ZhangJingqing ZhangJinwei ZhangJiong ZhangJun ZhangLe ZhangLei ZhangLichi ZhangLin ZhangLing ZhangLu ZhangMiaomiao ZhangNing ZhangPengfei ZhangPengyue ZhangQiang ZhangRongzhao ZhangRu-Yuan ZhangShanzhuo ZhangShu ZhangTong ZhangWei ZhangWeiwei ZhangWenlu ZhangXiaoyun ZhangXin ZhangYa ZhangYanbo ZhangYanfu Zhang

Organization xxvii

Yi ZhangYifan ZhangYizhe ZhangYongqin ZhangYou ZhangYoushan ZhangYu ZhangYue ZhangYulun ZhangYunyan ZhangYuyao ZhangZijing ZhangCan ZhaoChangchen ZhaoFenqiang ZhaoGangming ZhaoHaifeng ZhaoHe ZhaoJun ZhaoLi ZhaoQingyu ZhaoRongchang ZhaoShen ZhaoTengda ZhaoTianyi ZhaoWei ZhaoXuandong ZhaoYitian ZhaoYiyuan ZhaoYu ZhaoYuan-Xing ZhaoYue ZhaoZixu ZhaoZiyuan ZhaoXingjian ZhenHao ZhengJiannan ZhengKang Zheng

Yalin ZhengYushan ZhengJia-Xing ZhongZichun ZhongHaoyin ZhouKang ZhouSanping ZhouTao ZhouWenjin ZhouXiao-Hu ZhouXiao-Yun ZhouYanning ZhouYi Zhou (IIAI)Yi Zhou (University of Utah)Yuyin ZhouZhen ZhouZongwei ZhouDajiang ZhuDongxiao ZhuHancan ZhuLei ZhuQikui ZhuWeifang ZhuWentao ZhuXiaofeng ZhuXinliang ZhuYingying ZhuYuemin ZhuZhe ZhuZhuotun ZhuXiahai ZhuangAneeq ZiaVeronika ZimmerDavid ZimmererLilla ZölleiYukai ZouGerald ZwettlerReyer Zwiggelaa

xxviii Organization

Contents – Part III

CAI Applications

Reconstructing Sinus Anatomy from Endoscopic Video – Towardsa Radiation-Free Approach for Quantitative Longitudinal Assessment . . . . . . 3

Xingtong Liu, Maia Stiber , Jindan Huang , Masaru Ishii,Gregory D. Hager, Russell H. Taylor, and Mathias Unberath

Inertial Measurements for Motion Compensation in Weight-BearingCone-Beam CT of the Knee . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14

Jennifer Maier, Marlies Nitschke, Jang-Hwan Choi, Garry Gold,Rebecca Fahrig, Bjoern M. Eskofier, and Andreas Maier

Feasibility Check: Can Audio Be a Simple Alternative to Force-BasedFeedback for Needle Guidance? . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24

Alfredo Illanes, Axel Boese, Michael Friebe, and Christian Hansen

A Graph-Based Method for Optimal Active Electrode Selectionin Cochlear Implants . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34

Erin Bratu, Robert Dwyer, and Jack Noble

Improved Resection Margins in Surgical Oncology Using IntraoperativeMass Spectrometry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 44

Amoon Jamzad, Alireza Sedghi, Alice M. L. Santilli,Natasja N. Y. Janssen, Martin Kaufmann, Kevin Y. M. Ren,Kaitlin Vanderbeck, Ami Wang, Doug McKay, John F. Rudan,Gabor Fichtinger, and Parvin Mousavi

Self-Supervised Domain Adaptation for Patient-Specific, Real-TimeTissue Tracking . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54

Sontje Ihler, Felix Kuhnke, Max-Heinrich Laves, and Tobias Ortmaier

An Interactive Mixed Reality Platform for Bedside Surgical Procedures . . . . . 65Ehsan Azimi, Zhiyuan Niu, Maia Stiber, Nicholas Greene, Ruby Liu,Camilo Molina, Judy Huang, Chien-Ming Huang, and Peter Kazanzides

Ear Cartilage Inference for Reconstructive Surgery with ConvolutionalMesh Autoencoders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 76

Eimear O’ Sullivan, Lara van de Lande, Antonia Osolos,Silvia Schievano, David J. Dunaway, Neil Bulstrode,and Stefanos Zafeiriou

Robust Multi-modal 3D Patient Body Modeling . . . . . . . . . . . . . . . . . . . . . 86Fan Yang, Ren Li, Georgios Georgakis, Srikrishna Karanam,Terrence Chen, Haibin Ling, and Ziyan Wu

A New Electromagnetic-Video Endoscope Tracking Method viaAnatomical Constraints and Historically Observed Differential Evolution . . . . 96

Xiongbiao Luo

Malocclusion Treatment Planning via PointNet Based SpatialTransformation Network . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 105

Xiaoshuang Li, Lei Bi, Jinman Kim, Tingyao Li, Peng Li, Ye Tian,Bin Sheng, and Dagan Feng

Simulation of Brain Resection for Cavity Segmentation Using Self-supervised and Semi-supervised Learning. . . . . . . . . . . . . . . . . . . . . . . . . . 115

Fernando Pérez-García, Roman Rodionov, Ali Alim-Marvasti,Rachel Sparks, John S. Duncan, and Sébastien Ourselin

Local Contractive Registration for Quantification of Tissue Shrinkagein Assessment of Microwave Ablation . . . . . . . . . . . . . . . . . . . . . . . . . . . . 126

Dingkun Liu, Tianyu Fu, Danni Ai, Jingfan Fan, Hong Song,and Jian Yang

Reinforcement Learning of Musculoskeletal Control fromFunctional Simulations. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 135

Emanuel Joos, Fabien Péan, and Orcun Goksel

Image Registration

MvMM-RegNet: A New Image Registration Framework Basedon Multivariate Mixture Model and Neural Network Estimation . . . . . . . . . . 149

Xinzhe Luo and Xiahai Zhuang

Database Annotation with Few Examples: An Atlas-Based FrameworkUsing Diffeomorphic Registration of 3D Trees . . . . . . . . . . . . . . . . . . . . . . 160

Pierre-Louis Antonsanti, Thomas Benseghir, Vincent Jugnon,and Joan Glaunès

Pair-Wise and Group-Wise Deformation Consistency in DeepRegistration Network . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 171

Dongdong Gu, Xiaohuan Cao, Shanshan Ma, Lei Chen, Guocai Liu,Dinggang Shen, and Zhong Xue

Semantic Hierarchy Guided Registration Networks for Intra-subjectPulmonary CT Image Alignment. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 181

Liyun Chen, Xiaohuan Cao, Lei Chen, Yaozong Gao, Dinggang Shen,Qian Wang, and Zhong Xue

xxx Contents – Part III

Highly Accurate and Memory Efficient Unsupervised Learning-BasedDiscrete CT Registration Using 2.5D Displacement Search. . . . . . . . . . . . . . 190

Mattias P. Heinrich and Lasse Hansen

Unsupervised Learning Model for Registration of Multi-phaseUltra-Widefield Fluorescein Angiography. . . . . . . . . . . . . . . . . . . . . . . . . . 201

Gyoeng Min Lee, Kwang Deok Seo, Hye Ju Song, Dong Geun Park,Ga Hyung Ryu, Min Sagong, and Sang Hyun Park

Large Deformation Diffeomorphic Image Registration with LaplacianPyramid Networks. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 211

Tony C. W. Mok and Albert C. S. Chung

Adversarial Uni- and Multi-modal Stream Networks for MultimodalImage Registration . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 222

Zhe Xu, Jie Luo, Jiangpeng Yan, Ritvik Pulya, Xiu Li, William Wells III,and Jayender Jagadeesan

Cross-Modality Multi-atlas Segmentation Using Deep Neural Networks . . . . . 233Wangbin Ding, Lei Li, Xiahai Zhuang, and Liqin Huang

Longitudinal Image Registration with Temporal-Orderand Subject-Specificity Discrimination . . . . . . . . . . . . . . . . . . . . . . . . . . . . 243

Qianye Yang, Yunguan Fu, Francesco Giganti, Nooshin Ghavami,Qingchao Chen, J. Alison Noble, Tom Vercauteren, Dean Barratt,and Yipeng Hu

Flexible Bayesian Modelling for Nonlinear Image Registration . . . . . . . . . . . 253Mikael Brudfors, Yaël Balbastre, Guillaume Flandin,Parashkev Nachev, and John Ashburner

Are Registration Uncertainty and Error Monotonically Associated? . . . . . . . . 264Jie Luo, Sarah Frisken, Duo Wang, Alexandra Golby,Masashi Sugiyama, and William Wells III

MR-to-US Registration Using Multiclass Segmentation of HepaticVasculature with a Reduced 3D U-Net . . . . . . . . . . . . . . . . . . . . . . . . . . . 275

Bart R. Thomson, Jasper N. Smit, Oleksandra V. Ivashchenko,Niels F. M. Kok, Koert F. D. Kuhlmann, Theo J. M. Ruers,and Matteo Fusaglia

Detecting Pancreatic Ductal Adenocarcinoma in Multi-phase CT Scansvia Alignment Ensemble . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 285

Yingda Xia, Qihang Yu, Wei Shen, Yuyin Zhou, Elliot K. Fishman,and Alan L. Yuille

Contents – Part III xxxi

Biomechanics-Informed Neural Networks for Myocardial Motion Trackingin MRI . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 296

Chen Qin, Shuo Wang, Chen Chen, Huaqi Qiu, Wenjia Bai,and Daniel Rueckert

Fluid Registration Between Lung CT and Stationary ChestTomosynthesis Images . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 307

Lin Tian, Connor Puett, Peirong Liu, Zhengyang Shen,Stephen R. Aylward, Yueh Z. Lee, and Marc Niethammer

Anatomical Data Augmentation via Fluid-Based Image Registration . . . . . . . 318Zhengyang Shen, Zhenlin Xu, Sahin Olut, and Marc Niethammer

Generalizing Spatial Transformers to Projective Geometry withApplications to 2D/3D Registration . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 329

Cong Gao, Xingtong Liu, Wenhao Gu, Benjamin Killeen,Mehran Armand, Russell Taylor, and Mathias Unberath

Instrumentation and Surgical Phase Detection

TeCNO: Surgical Phase Recognition with Multi-stage TemporalConvolutional Networks. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 343

Tobias Czempiel, Magdalini Paschali, Matthias Keicher, Walter Simson,Hubertus Feussner, Seong Tae Kim, and Nassir Navab

Surgical Video Motion Magnification with Suppressionof Instrument Artefacts . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 353

Mirek Janatka, Hani J. Marcus, Neil L. Dorward, and Danail Stoyanov

Recognition of Instrument-Tissue Interactions in Endoscopic Videosvia Action Triplets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 364

Chinedu Innocent Nwoye, Cristians Gonzalez, Tong Yu,Pietro Mascagni, Didier Mutter, Jacques Marescaux, and Nicolas Padoy

AutoSNAP: Automatically Learning Neural Architectures for InstrumentPose Estimation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 375

David Kügler, Marc Uecker, Arjan Kuijper,and Anirban Mukhopadhyay

Automatic Operating Room Surgical Activity Recognitionfor Robot-Assisted Surgery. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 385

Aidean Sharghi, Helene Haugerud, Daniel Oh, and Omid Mohareri

xxxii Contents – Part III

Navigation and Visualization

Can a Hand-Held Navigation Device Reduce Cognitive Load?A User-Centered Approach Evaluated by 18 Surgeons. . . . . . . . . . . . . . . . . 399

Caroline Brendle, Laura Schütz, Javier Esteban, Sandro M. Krieg,Ulrich Eck, and Nassir Navab

Symmetric Dilated Convolution for Surgical Gesture Recognition . . . . . . . . . 409Jinglu Zhang, Yinyu Nie, Yao Lyu, Hailin Li, Jian Chang,Xiaosong Yang, and Jian Jun Zhang

Deep Selection: A Fully Supervised Camera Selection Networkfor Surgery Recordings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 419

Ryo Hachiuma, Tomohiro Shimizu, Hideo Saito, Hiroki Kajita,and Yoshifumi Takatsume

Interacting with Medical Volume Data in Projective Augmented Reality . . . . 429Florian Heinrich, Kai Bornemann, Kai Lawonn, and Christian Hansen

VR Simulation of Novel Hands-Free Interaction Concepts for SurgicalRobotic Visualization Systems . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 440

Fang You, Rutvik Khakhar, Thomas Picht, and David Dobbelstein

Spatially-Aware Displays for Computer Assisted Interventions . . . . . . . . . . . 451Alexander Winkler, Ulrich Eck, and Nassir Navab

Ultrasound Imaging

Sensorless Freehand 3D Ultrasound Reconstruction via DeepContextual Learning . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 463

Hengtao Guo, Sheng Xu, Bradford Wood, and Pingkun Yan

Ultra2Speech - A Deep Learning Framework for Formant FrequencyEstimation and Tracking from Ultrasound Tongue Images . . . . . . . . . . . . . . 473

Pramit Saha, Yadong Liu, Bryan Gick, and Sidney Fels

Ultrasound Video Summarization Using Deep Reinforcement Learning . . . . . 483Tianrui Liu, Qingjie Meng, Athanasios Vlontzos, Jeremy Tan,Daniel Rueckert, and Bernhard Kainz

Predicting Obstructive Hydronephrosis Based on Ultrasound Alone . . . . . . . . 493Lauren Erdman, Marta Skreta, Mandy Rickard,Carson McLean, Aziz Mezlini, Daniel T. Keefe, Anne-Sophie Blais,Michael Brudno, Armando Lorenzo, and Anna Goldenberg

Semi-supervised Training of Optical Flow Convolutional NeuralNetworks in Ultrasound Elastography . . . . . . . . . . . . . . . . . . . . . . . . . . . . 504

Ali K. Z. Tehrani, Morteza Mirzaei, and Hassan Rivaz

Contents – Part III xxxiii

Three-Dimensional Thyroid Assessment from Untracked2D Ultrasound Clips . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 514

Wolfgang Wein, Mattia Lupetti, Oliver Zettinig, Simon Jagoda,Mehrdad Salehi, Viktoria Markova, Dornoosh Zonoobi,and Raphael Prevost

Complex Cancer Detector: Complex Neural Networks on Non-stationaryTime Series for Guiding Systematic Prostate Biopsy . . . . . . . . . . . . . . . . . . 524

Golara Javadi, Minh Nguyen Nhat To, Samareh Samadi,Sharareh Bayat, Samira Sojoudi, Antonio Hurtado, Silvia Chang,Peter Black, Parvin Mousavi, and Purang Abolmaesumi

Self-Supervised Contrastive Video-Speech Representation Learningfor Ultrasound . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 534

Jianbo Jiao, Yifan Cai, Mohammad Alsharid, Lior Drukker,Aris T. Papageorghiou, and J. Alison Noble

Assisted Probe Positioning for Ultrasound Guided Radiotherapy UsingImage Sequence Classification . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 544

Alex Grimwood, Helen McNair, Yipeng Hu, Ester Bonmati,Dean Barratt, and Emma J. Harris

Searching Collaborative Agents for Multi-plane Localizationin 3D Ultrasound . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 553

Yuhao Huang, Xin Yang, Rui Li, Jikuan Qian, Xiaoqiong Huang,Wenlong Shi, Haoran Dou, Chaoyu Chen, Yuanji Zhang, Huanjia Luo,Alejandro Frangi, Yi Xiong, and Dong Ni

Contrastive Rendering for Ultrasound Image Segmentation. . . . . . . . . . . . . . 563Haoming Li, Xin Yang, Jiamin Liang, Wenlong Shi, Chaoyu Chen,Haoran Dou, Rui Li, Rui Gao, Guangquan Zhou, Jinghui Fang,Xiaowen Liang, Ruobing Huang, Alejandro Frangi, Zhiyi Chen,and Dong Ni

An Unsupervised Approach to Ultrasound Elastography with End-to-endStrain Regularisation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 573

Rémi Delaunay, Yipeng Hu, and Tom Vercauteren

Automatic Probe Movement Guidance for Freehand Obstetric Ultrasound . . . 583Richard Droste, Lior Drukker, Aris T. Papageorghiou,and J. Alison Noble

Video Image Analysis

ISINet: An Instance-Based Approach for SurgicalInstrument Segmentation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 595

Cristina González, Laura Bravo-Sánchez, and Pablo Arbelaez

xxxiv Contents – Part III

Reliable Liver Fibrosis Assessment from Ultrasound Using GlobalHetero-Image Fusion and View-Specific Parameterization . . . . . . . . . . . . . . 606

Bowen Li, Ke Yan, Dar-In Tai, Yuankai Huo, Le Lu, Jing Xiao,and Adam P. Harrison

Toward Rapid Stroke Diagnosis with Multimodal Deep Learning . . . . . . . . . 616Mingli Yu, Tongan Cai, Xiaolei Huang, Kelvin Wong, John Volpi,James Z. Wang, and Stephen T. C. Wong

Learning and Reasoning with the Graph Structure Representationin Robotic Surgery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 627

Mobarakol Islam, Lalithkumar Seenivasan, Lim Chwee Ming,and Hongliang Ren

Vision-Based Estimation of MDS-UPDRS Gait Scores for AssessingParkinson’s Disease Motor Severity. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 637

Mandy Lu, Kathleen Poston, Adolf Pfefferbaum, Edith V. Sullivan,Li Fei-Fei, Kilian M. Pohl, Juan Carlos Niebles, and Ehsan Adeli

Searching for Efficient Architecture for Instrument Segmentationin Robotic Surgery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 648

Daniil Pakhomov and Nassir Navab

Unsupervised Surgical Instrument Segmentation via Anchor Generationand Semantic Diffusion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 657

Daochang Liu, Yuhui Wei, Tingting Jiang, Yizhou Wang,Rulin Miao, Fei Shan, and Ziyu Li

Towards Accurate and Interpretable Surgical Skill Assessment:A Video-Based Method Incorporating Recognized Surgical Gesturesand Skill Levels . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 668

Tianyu Wang, Yijie Wang, and Mian Li

Learning Motion Flows for Semi-supervised Instrument Segmentationfrom Robotic Surgical Video . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 679

Zixu Zhao, Yueming Jin, Xiaojie Gao, Qi Dou, and Pheng-Ann Heng

Spectral-spatial Recurrent-Convolutional Networks for In-VivoHyperspectral Tumor Type Classification . . . . . . . . . . . . . . . . . . . . . . . . . . 690

Marcel Bengs, Nils Gessert, Wiebke Laffers, Dennis Eggert,Stephan Westermann, Nina A. Mueller, Andreas O. H. Gerstner,Christian Betz, and Alexander Schlaefer

Synthetic and Real Inputs for Tool Segmentation in Robotic Surgery . . . . . . 700Emanuele Colleoni, Philip Edwards, and Danail Stoyanov

Contents – Part III xxxv

Perfusion Quantification from Endoscopic Videos: Learning to ReadTumor Signatures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 711

Sergiy Zhuk, Jonathan P. Epperlein, Rahul Nair, Seshu Tirupathi,Pól Mac Aonghusa, Donal F. O’Shea, and Ronan Cahill

Asynchronous in Parallel Detection and Tracking (AIPDT): Real-TimeRobust Polyp Detection . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 722

Zijian Zhang, Hong Shang, Han Zheng, Xiaoning Wang, Jiajun Wang,Zhongqian Sun, Junzhou Huang, and Jianhua Yao

OfGAN: Realistic Rendition of Synthetic Colonoscopy Videos . . . . . . . . . . . 732Jiabo Xu, Saeed Anwar, Nick Barnes, Florian Grimpen, Olivier Salvado,Stuart Anderson, and Mohammad Ali Armin

Two-Stream Deep Feature Modelling for Automated Video EndoscopyData Analysis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 742

Harshala Gammulle, Simon Denman, Sridha Sridharan,and Clinton Fookes

Rethinking Anticipation Tasks: Uncertainty-Aware Anticipation of SparseSurgical Instrument Usage for Context-Aware Assistance . . . . . . . . . . . . . . . 752

Dominik Rivoir, Sebastian Bodenstedt, Isabel Funke,Felix von Bechtolsheim, Marius Distler, Jürgen Weitz,and Stefanie Speidel

Deep Placental Vessel Segmentation for Fetoscopic Mosaicking . . . . . . . . . . 763Sophia Bano, Francisco Vasconcelos, Luke M. Shepherd,Emmanuel Vander Poorten, Tom Vercauteren, Sebastien Ourselin,Anna L. David, Jan Deprest, and Danail Stoyanov

Deep Multi-view Stereo for Dense 3D Reconstruction from MonocularEndoscopic Video . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 774

Gwangbin Bae, Ignas Budvytis, Chung-Kwong Yeung,and Roberto Cipolla

Endo-Sim2Real: Consistency Learning-Based Domain Adaptationfor Instrument Segmentation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 784

Manish Sahu, Ronja Strömsdörfer, Anirban Mukhopadhyay,and Stefan Zachow

Author Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 795

xxxvi Contents – Part III