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Lecture 15: Pathogenicity
Dr. Dimos
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Pathogenicity Vs. Virulence
Pathogenicity: is a broad conceptthat describes an organisms
potentialto cause infection or disease.
Virulence:is the accurate term fordescribing the degree of
pathogenicity.
The virulence of a microbe is
determined by its ability to 1!establish itself in the host and
"!cause damage.
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The steps involved #hen a microbecauses disease in a host.
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chanisms of adhesionby pathogens.
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Three #ays microbesdamage the host.
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The origins and e%ects of circulatinge&oto&ins and
endoto&in.
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'tages in the course of infection
and disease
Dashed lines represent periods #ith a
variable length.
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Disease Table (ontinued:
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)astrointestinalTract
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'almonella
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'lamonella *dhering and +nvading
)ut $ucosa
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Pathogenicity+sland
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'tructure of the 'almonella type +++secretion system T,''!
P th i it + l d
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Pathogenicity +sland
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+mmune 'ystem
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*ntibody$olecule
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The -ive Types of *ntibodies
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o# *ntibodies +nterac#ith *ntigens
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The Process of*naphyla&is and
*llergy
