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LECTURE 05: CHROMOSOMAL BASIS OF INHERITANCE II
CH3 key concepts historical development of
the chromosome theory... genetics + cell biology
chromosomes mitosis & meiosis chromosome behavior &
inheritance patterns organelle chromosomes*
MENDELIAN ANALYSIS: 2 GENES
MENDELIAN ANALYSIS: 2 GENES
MITOSIS & MEIOSIS
MITOSIS & MEIOSIS
cell cycle
INTERPHASE
MITOSIS & MEIOSIS
sisterchromatids
MITOSIS & MEIOSIS
microtubule attachment to the kinetochore
MITOSIS & MEIOSIS
MITOSIS & MEIOSIS
sister chromatidsseparate poles
nuclear spindle prominentchromosomes equatorial plane
sister chromatidscluster poles
chromosomesuncoil;
nuclear membranereappears
visible sister chromatids;
nuclear membranebreak down
chromosomescondense
MITOSIS & MEIOSIS
I: reduction division: 2n n
sisterchromatids
non-sisterchromatids
tetrads, orbivalents
homologous chromosomes or homologues
MITOSIS & MEIOSIS
centromeresdivide
II: mitotic division: n n
no pairing(with what?)
MITOSIS & MEIOSIS
Prophase I
MITOSIS & MEIOSIS
MITOSIS & MEIOSIS
MITOSIS & MEIOSIS
MITOSIS & MEIOSIS
MITOSIS & MEIOSIS
MITOSIS & MEIOSIS
MITOSIS & MEIOSIS
bivalent pairing due to synaptonemal complex proteins associated with chromatid crossing over @ chiasmata
MITOSIS & MEIOSIS
MITOSIS & MEIOSIS
MITOSIS & MEIOSIS
MITOSIS & MEIOSIS
MITOSIS & MEIOSIS
MITOSIS & MEIOSIS
MITOSIS & MEIOSIS
CHROMOSOMES & INHERITANCE
DIPLOIDLIFE CYCLE
CHROMOSOMES & INHERITANCE
HAPLOIDLIFE CYCLE
CHROMOSOMES & INHERITANCE
ALTERNATINGLIFE CYCLE
(PLANTS)
CHROMOSOMES & INHERITANCE
ALTERNATINGLIFE CYCLE
OF CORN
CHROMOSOMES & INHERITANCE
CHROMOSOMES & INHERITANCE
CHROMOSOMES & INHERITANCE
CHROMOSOMES & INHERITANCE
CHROMOSOMES & INHERITANCE
CHROMOSOMES & INHERITANCE+
+
–
–
Neurospora
crassa
haploidfungus
CHROMOSOMES & INHERITANCE
CHROMOSOMES & INHERITANCE
CHROMOSOMES & INHERITANCE
wild type mutant pink x albino al+ al
that’s better ... centromeres illustrated correctly...
equivalent daughter cells
CHROMOSOMES & INHERITANCE
mitosis in diploid cell dihybrid A/a ; B/b ... centromeres illustrated
incorrectly... (text books do this sometimes)
meiosis in diploid cell dihybrid A/a ; B/b segregation independent assortment 1:1:1:1 gametic ratio
CHROMOSOMES & INHERITANCE
CHROMOSOMES & INHERITANCE
CHROMOSOMAL BASIS OF INHERITANCE: PROBLEMS
in Griffiths chapter 3, beginning on page 109, you should be able to do questions 1, 2, 5-10, 12, 16, 18-20, 22, 25-30, 32, 33, 40
begin with the solved problems on page 108 if you are having difficulty
try Schaum’s Outline questions in chapter 1