View
218
Download
2
Tags:
Embed Size (px)
Citation preview
LeadershipLawrence Cornett, Ph.D., University of AR for Medical Sciences
Helen Beneš, Ph.D., University of AR for Medical SciencesDonald Bobbitt, Ph.D., University of Arkansas, Fayetteville
Mary Good, Ph.D., University of Arkansas at Little Rock
Caroline Miller-Robinson, B.S. – Project CoordinatorAlice R. Smith, B.A. – Special Projects
Founded October 2001 by
3-year $6,000,000 Grant Award from NIH NCRR’s IDeA Program
IDeA StatesIDeA States
Purpose of BRIN: to promote biomedical research infrastructure
in IDeA States (NIH/NCRR)
Arkansas
Rank*
*NSF/NIH
Total R&D (2000) $ 454,401 42
Academic R&D (2000) $ 130,894 40
Total R&D/GSP (2000) 0.67 47
($$ in thousands)*
0
10
20
30
40
50
60
2000 2001 2002
NIH
Fund
ing
(mill
ions
of
dolla
rs)
Institutions Involved in Arkansas BRIN
Arkansas State University
University of Arkansasat Pine Bluff
Hendrix College
University of Central Arkansas
University of Arkansas
at Monticello
Lyon College
Arkansas Tech University
Ouachita Baptist University
UALR
UAMS
UAF
Harding University
John Brown University
Henderson State University
Arkansas BRIN Organization
• Expand biomedical research opportunities for undergraduate faculty and students through collaborations with graduate research institutions in Arkansas
• Stimulate more proposals for federal grants in the biomedical sciences from Arkansas scientists
• Advance statewide expertise in the rapidly developing disciplines of bioinformatics, genomics, proteomics and digital microscopy
BioinformaticsCore
AdministrativeCore
Recruitment/Mentoring
Core
BiotechnologyCore
Steering Committee
External Advisory
Committee
Administrative Core
• Develop website, http://BRIN.UAMS.edu
• Develop promotional materials
• Promote collaborations and participation in
the Arkansas BRIN through outreach
activities
• Provide support for other Cores
Presentations: • Science Policy• Biotechnology Company
Sales• Government Research• Academic Research
Student Career DayApril 2002 & April 2003 – Total of 102 undergraduate students
representing 11 undergraduate universities & colleges in Arkansas
Outreach Activities
Grant Writing Workshop
• Pharmaceutical
Research• Pharmaceutical sales• Scientific
Correspondence• Patent Law
June 27, 2003 – 23 BRIN faculty Keynote speaker Anthony Coelho, Jr., PhD, Review Policy Officer, NIH
Concurrent workshops: • Grant writing for success• Mock Study Session• Peer Review Process
• An Eye on the Clock – Time
Management• Dos & Don’ts of Grant Writing• IRB & IACUC
Biotechnology Core
• Enhance existing facilities
• Expand research opportunities for undergraduate faculty and students through access to instrumentation and expertise
• Advance statewide expertise in the rapidly developing disciplines of genomics, proteomics and digital microscopy
• Sponsor workshops to educate researchers in different disciplines
Genomics, Proteomics and Digital Microscopy Facilities
Proteomics WorkshopUniversity of Arkansas,
FayettevilleJune 2003
cDNA Microarray Core Facility
Proteomics Facilities
Digital Microscopy FacilityOnline Tutorial
July 2003
UAMS Facility UAF Facility
Microarray Working Group - Bimonthly Meetings
Microarray Symposium for BRIN Fellows, June 2002
BioinformaticsBioinformatics Core Core
Central goal:to create a critical mass of faculty and
support staff with expertise in bioinformatics &
to facilitate their communication & interaction to meet needs of the AR research community
Director: Mary Good, Ph.D. Associate Directors: Steve F. Jennings, Ph.D. –
EducationGary Thompson, Ph.D. – Research
Definitions for BIOINFORMATICS:
• a novel discipline integrating computer and information science to acquire, organize, store, analyze, and visualize biological and biomedical data
• a discipline building upon computational biology to develop and apply methods for data analysis, mathematical modeling and computational simulation techniques to study biological systems
• Recruit Bioinformatics Faculty UAF, UALR & UAMS
• Develop a Joint Graduate Program in BioinformaticsUALR, UAF, UAMS
• Establish Access Grid StudiosTo facilitate interactions among Arkansas BRIN institutions
Bioinformatics Core
Faculty RecruitmentsFaculty Recruitments
• Tom Kieber-Emmons, Ph.D. to UAMS
Director of Basic Breast Cancer Research
http:/bioinformatics.uams.edu
Established The Bioinformatics Center
• Steve L. Jennings, Ph.D. to UALR
Associate Director of BRIN’S Bioinformatics CoreEstablished the
MidSouth Regional Center for Bioinformatics
ArkansasAccess Grid Conference
CentersUniversity of Arkansas at Little
Rock
University of ArkansasHoused at Mullins LibraryEst. completion Fall 2003
Access Grid Conference Centers under construction
Arkansas State UniversityHoused at Dean B. Ellis
LibraryEst. completion Fall 2003
University of Arkansas for Medical Sciences
Recruitment & Mentoring Core
• Support recruitment of faculty to undergraduate institutions
• Provide mentored research opportunities for undergraduate faculty
• Provide summer research opportunities for undergraduate students
Students select a research lab
Arkansas BRIN provides• Stipend• Housing/Travel Allowance• Research Supply Budget
Students agree to• Present a poster at Arkansas BRIN Research
Day• Prepare a research paper
Mentored Student Fellowships
Summer 2003 – 16 Funded
UAPB
ASU
Lyon
UCA
Hendrix
UAF
OBU
UAM
UALR
Mentored Student Success
2003 – B.S. from UALR in
Management Information Systems & Business Administration
2003 – hired full-time by Microarray Core Facility (UAMS)
to interface databases & work with Bioinformatics Center
Nikiya Meeks -
2002 BRIN Summer Fellow
UAPB
ASU
Lyon
UCA
Hendrix
JBU
OBU
Faculty Recruitment to Undergraduate
Institutions
Arkansas BRIN provides: A startup package
Undergraduate school agrees to
• A tenure-track faculty appointment with an institutional (9-month) salary commitment
• A commitment to sufficient protected time for faculty development of a research program
Faculty agree to• Commitment to developing a research program • Involvement in the Arkansas BRIN• Involve students in research
Mentored Faculty Fellowships
Faculty & Mentor prepare proposal
Arkansas BRIN provides:• Stipend• Housing/Travel Allowance • Research Supply Budget
Faculty agree to:• Build long term relationship with
mentor• Involve undergraduate students in
research
UAPB
ASULyon
UCA
Hendrix
JBU
OBU
Harding
HSU
ATU
Summer & Academic-Year – 20 Funded
Mentored Faculty Successes
• Pradip Bandyopadhyay, Ph.D. - Professor, Hendrix CollegeReceived a fundable score for an NIH AREA Grant to continue research started with Arkansas BRIN funding
• Mark Sutherland, Ph.D. - Associate Professor, Hendrix College Summer research continued with funding from mentor’s NSF supplement
• Philip Jemilohun, Ph.D. - Assistant Professor, Recruited to UAPBReceived a fundable score for an NIH AREA Grant
• Anne Grippo, Ph.D. and Roger Buchanan, Ph.D. - Associate Professors, AR State University Research now being funded by the Arkansas Biosciences Institute
Arkansas Biomedical Research Infrastructure
Network
UAM
UAPB
UAMSUALR
Hendrix
ASUUAF Lyon
OBU
UCA
HSU
JBU
HardingHendrix
ATU
MidSouth Regional Center for Bioinformatics
• Established by funding from AR BRIN & UALR’s CyberCollege
Steven F. Jennings – Executive DirectorRoger Hall – Technical DirectorLisa Henderson – Managing Director
• Equipment – Sun Microsystems (matching grant)
• Workshop on Programming Skills for Bioinformatics Software
4 sessions, June – August 2003: “Use of perl and bioperl”
• NSF EPSCoR grant proposal to fund outreach programs
• Plans for I2 connection to UAMS to support Oracle database & Spotfire Microarray Analysis software
• Jointly offered by UAMS & UALR Faculty
• Exploiting Unique Expertises of Each Campus:Information & Computer Science; BiostatisticsBiomedical Research
• Curriculum built of currently taught and new courses
• Lab rotations in four Core Areas – bioinformatics, life sciences, biostatistics, computer & information sciences
• M.S., Ph.D. degrees or Advanced Professional Certificate
Joint Graduate Program in Bioinformatics