76
Latest Research in the field of Homeopathy & Medical Sciences: In India & throughout the world DR.K.M.NISANTH NAMBISON M.D (Hom.), FBIH (Lon.), PGDCA, MDP (IIM) (Gold Medalist) Ass. Professor, Surgery Department, Govt. Homoeopathic Medical College, Bhopal (M.P) www.nambisons.com , www.diagnozit.com

Latest research in Homeopathy

Embed Size (px)

DESCRIPTION

Latest researches in Homeopathy has been complied to show effectiveness of Homeopathy & its scientificity.

Citation preview

Page 1: Latest research in Homeopathy

Latest Research in the field of Homeopathy & Medical Sciences: In

India & throughout the world

DR.K.M.NISANTH NAMBISONM.D (Hom.), FBIH (Lon.), PGDCA, MDP (IIM)

(Gold Medalist)Ass. Professor,

Surgery Department, Govt. Homoeopathic Medical College, Bhopal (M.P)

www.nambisons.com , www.diagnozit.com

Page 2: Latest research in Homeopathy

Salamat Petang

Page 3: Latest research in Homeopathy

Absence of evidence is not the evidence of

absence. -Dr. Carl Sagan

Page 4: Latest research in Homeopathy

Homeopathy is fast making inroads into the medical care sector. As always, Homeopaths confront with the question “Does Homeopathy have any good research?” “Does it really work?” “How does it work?” Lancet published a paper on 27 August, 2005 claiming that ‘Homeopathy is Placebo’ which made the situation worse.

Page 5: Latest research in Homeopathy

This paper aims at exploring the development in the field of Homoeopathy & Modern Medicine to enable every Homeopath to defend his science in the society, & expose the lawlessness of the so-called Modern Medicine.

Page 6: Latest research in Homeopathy

The most controversial & debated issue in Homeopathy is serially diluted Homeopathic Medicines.

According to Physicist Robert L. Park, former executive director of the American Physical Society, has noted that since the least amount of a substance in a solution is one molecule

This would require a container more than

30,000,000,000 times the size of the Earth

a 30C would have to have at least one molecule of the original substance solution dissolved in a minimum of

1,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000, 000,000,000,000,000 molecules of water.

Page 7: Latest research in Homeopathy

" Park has also noted that "to expect to get even one molecule of the 'medicinal' substance allegedly present in 30X pills, it would be necessary to take some two billion of them, which would total about a thousand tons of lactose plus whatever impurities the lactose contained".

The laws of chemistry state that there is a limit to the dilution that can be made without losing the original substance altogether. This limit, which is related to

Avogadro's number, is roughly equal to homeopathic

potencies of 12C or 24X (1 part in 1024).

(Ernst E (2005). "Is homeopathy a clinically valuable approach?". Trends Pharmacol. Sci. 26 (11): 547–8.)

Page 8: Latest research in Homeopathy

Luc Montagnier is a French virologist and joint recipient of the 2008 Nobel Prize in Physiology/Medicine, for his discovery of the Human Immunodeficiency Virus (HIV).

Luc Montagnier

Page 9: Latest research in Homeopathy

Electromagnetic signals from bacterial DNA

Montagnier has published research detecting electromagnetic signals (EMS) from bacterial DNA (M. Pirum and E. Coli) after serial agitated dilution in water, and detection of EMS in the plasma and in the DNA extracted from the plasma of patients with Alzheimer's and Parkinson's disease, multiple sclerosis and rheumatoid arthritis.

Page 10: Latest research in Homeopathy

Luc MONTAGNIER et al. Filtrated of a culture supernatant of Mycoplasma pirum, yielded apparently sterile fluid. The first low dilutions were usually negative (no EMS), showing the background noise only. But, Positive signals (Emitting EMS) were obtained at dilutions ranging from 10−5 to 10−8 or 10−12.

Page 11: Latest research in Homeopathy
Page 12: Latest research in Homeopathy
Page 13: Latest research in Homeopathy

Some more examples, make us realize that high diluted or single molecule can actually do lot of things:

•Beta-endorphins are known to modulate natural killer-cell

activity in dilutions of 10-18.

•Interleukin-1, an important part of the immune system, has

been found to exhibit increased T-cell clone proliferation at <10-19. •Pheromones emitted by animals and insects, result in hypersensitive reactions with even a single molecule. (Scientists, as on date, have no means to assess the effects of any thing which has no molecule.)

(Dana Ullman, Homeopathic Medicine: Making The Case For Nanopharmacology Nutrition Science News Spring 2002)

Page 14: Latest research in Homeopathy

This what the skeptics of Homeopathy trying to do.

Page 15: Latest research in Homeopathy

WHO report, which states that most of the studies published in the last 40 years have shown homeopathic remedies to be superior to placebo and "equivalent to conventional medicines in the treatment of illnesses, in both humans and animals".

Page 16: Latest research in Homeopathy

The World Health Organisation states that Homoeopathy is the second most used medical system internationally, with over $1 Billon in expenditures for such therapy.

Lawrence M.Tierney, Jr. et al, “Current Medical Diagnosis & Treatment”, USA: The McGraw-Hill Companies, Inc. 2004 (1701-03; 43Ed)

Page 17: Latest research in Homeopathy

Here are some of the popular Homeopathic researches complied & categorized to make everyone realize

that a lot of work has been done in this area:

META-ANALYSIS

Page 18: Latest research in Homeopathy

Twenty to 30 percent of French & German physicians use Homoeopathy in clinical practice. In Great Britain, five Homoeopathic hospitals are part of the National health System, and over 30% of generalists use Homoeopathy. In the United states, there are more that 500 physicians and 5000 non-physicians using Homoeopathy in clinical practice, and 2.5 million Americans currently use Homoeopathic medicines – of which two-thirds are self-prescribed spending more than $250 million annually.

Page 19: Latest research in Homeopathy

In 1987, one of the internationally important Homeopathic research which took the centerstage was done by French immunologist Jacques Benveniste who submitted a paper to the journal Nature while working at INSERM. The paper purported to have discovered that basophils released histamine when exposed to a homeopathic dilution of anti-immunoglobulin E, a type of white blood cell.

Page 20: Latest research in Homeopathy

Are the Clinical Effects of Homeopathy Placebo Effects? A Meta-analysis of Placebo-Controlled Trials: This state of the art Meta analysis reviewed 186 studies, 89 of which fit pre-defined criteria. Rather than count and compare the number of trials, which show efficacy of treatment, the researchers pooled the data from the various studies to assess data. The results showed that patients taking homeopathic medicines were 2.45 times more likely to experience a positive therapeutic effect than placebo. (K. Linde, N. Clausius, G. Ramirez, et al; September 20, 1997; Lancet, 350:834-843)

META-ANALYSIS

Page 21: Latest research in Homeopathy

Critical Review and Meta-Analysis of Serial Agitated

Dilutions in Experimental Toxicology:

This meta-analysis of 105 studies in toxicology showed

that homeopathic medicines may be useful in treating

toxic exposures. This meta-analysis was conducted by

a similar group of researchers who recently published a

meta-analysis on clinical studies in The Lancet.

META-ANALYSIS

(K. Linde, W.B. Jonas, D. Melchart, D., et al; January 1, 1994; Human and Experimental Toxicology, 1994, 13:481-92

Page 22: Latest research in Homeopathy

Clinical Trials of Homeopathy: This is the most widely cited meta-analysis of clinical research prior to 1991. This meta-analysis reviewed 107 studies of homeopathic medicines, 81 of which (or 77%) showed positive effect. Of the best 22 studies, 15 showed efficacy. The researchers concluded: "The evidence presented in this review would probably be sufficient for establishing homeopathy as a regular treatment for certain indications." Further, "The amount of positive evidence even among the best studies came as a surprise to us.“

J. Kleijnen, P. Knipschild, G. ter Riet: February 9, 1991: British Medical Journal, 302:316-323

META-ANALYSIS

Page 23: Latest research in Homeopathy

Skeptics of Homeopathy need a break….

Page 24: Latest research in Homeopathy

OTHER CLINICAL STUDIES

Homeopathic Treatment of Uterine Fibroid and Ovarian Cyst: Pulsatilla 200c,Medorrhinum 200c, Sabina 200c, Sepia 200c and Tuberculunum 1000c were used according to the presenting symptom for the treatment of Uterine Fibroid and Ovarian Cyst The patients were assessed on the basis changes in the symptoms during the period of 3-4 months and ultrasound done after that to assess the size of fibroid. Cure rate - 48%, Rate of positive response to Homeopathy treatment - 85%.

(Dr. G.K. Shangloo et al; April 18, 2007)

Page 25: Latest research in Homeopathy

OTHER CLINICAL STUDIES

Clinical management of idiopathic epilepsy in dogs with homeopathic Belladonna 200C: a case series:

Epilepsy is an important neurological disorder in dogs.

Belladonna 200C was evaluated in 10 dogs with idiopathic epilepsy. During the seizure phase, 3-4 drops of Belladonna 200C were administered orally at 15 min intervals until considerable reduction in seizure activity, then four times daily. Four dogs with head shaking syndrome in addition to seizures were given Cocculus 6C, 3-4 drops orally weekly for 3 months in addition.

Page 26: Latest research in Homeopathy

OTHER CLINICAL STUDIES

Numbers of fits reduced to 2-3 during first 2 weeks post-therapy and then became occasional in next 2 weeks. With continuation of Belladonna therapy, no fits were observed during 2-7 months follow-up. In two cases epileptic fits reappeared within 15-25 days of cessation of therapy. Belladonna therapy was resumed and seizure control was again achieved. Owners were advised to continue the therapy at least twice daily until there were no fits for 2-3 months. Liver specific enzymes were monitored, no abnormalities were observed.

(Homeopathy. 2007 Jan;96(1):46-8. JP Varshney; January 1, 2007; Division of Medicine, Indian Veterinary Research Institute, Izatnagar, India. [email protected] )

Page 27: Latest research in Homeopathy

Hospital Study Shows Improved Health in 70% of Patients Using Homeopathy:

The results of a six-year study at the Bristol Homeopathic Hospital in England showed that more that 70 percent of patients with severe illness showed very positive health changes after taking homeopathic remedies prescribed by their doctor.  More than 6,500 patients participated in this study.

Page 28: Latest research in Homeopathy

Hospital Study Shows Improved Health in 70% of Patients Using Homeopathy:

Diseases included eczema, asthma, migraine headaches, irritable bowel syndrome, menopause, arthritis, depression, and chronic fatigue syndrome.  The largest improvements were seen in children.  In fact, over 89% of children under the age of 16 with asthma reported significant improvement with homeopathic treatments.  Of this group, 75% felt either "better" or "much better", as did 68% of eczema patients under 16 years of age.

Page 29: Latest research in Homeopathy

Most of the patients in this study had tried conventional treatments first without any success.  This  study was

reported in the BBC News, November 21, 2005 and by the British Homeopathic Association.

D.S. Spence, et al; Journal of Alternative and Complementary Medicine, 2005, 11(5):793-798.

BBC News

Page 30: Latest research in Homeopathy

HOMEOPATHY versus CONVENTIONAL TREATMENT in respiratory tract complaints:

In an outcome study, 30 practitioners in four countries enrolled 500 consecutive patients with at least one of three complaints: upper respiratory tract complaints including allergies; lower respiratory tract complaints including allergies; or ear complaints. Of 456 patients, 281 received homeopathy and 175 conventional treatment.

Page 31: Latest research in Homeopathy

The primary outcomes criterion was response to treatment, defined as cured or major improvement after 14 days of treatment. Results showed a response rate of 82.6% in the homeopathy group compared to 67.3% in the group receiving conventional medicine. The authors concluded that homeopathy appeared to be at least as effective as conventional treatment of patients with the three conditions studied.

Riley D, Fischer M, Singh B, Haidvogl M, Heger M. Homeopathy and conventional medicine: an outcomes study comparingeffectiveness in a

primary care setting. J Altern Complement Med 2001; 7: 149–159.

Page 32: Latest research in Homeopathy

Sweet pills for children…..

Page 33: Latest research in Homeopathy

Homeopathic Treatment of ADHD (Attention Deficit Hyperactivity Disorder):

A Controlled Study: Forty-three children were randomly assigned to either placebo or homeopathic treatment groups, and then those initially given a placebo were given an individualized homeopathic medicine. All subjects underwent a homeopathic interview to determine which individualized remedy was appropriate. Results show significant improvement once the patient began taking the homeopathic medicine.

J. Lamont; British Homoeopathic Journal, October, 1997, 86:196-200.

Page 34: Latest research in Homeopathy

Acute Otitis Media in Children:

A Comparison of Conventional and Homeopathic Treatment: This study of 131 children allowed parents to choose homeopathic or conventional medical care from their ear, nose, and throat doctor. 103 children underwent homeopathic treatment, while 28 underwent conventional care. in German in Hals-Nasen-Ohren (Head, Nose, and Otolyngarology, August, 1996:462-66).

Page 35: Latest research in Homeopathy

Acute Otitis Media in Children: cont….

They found that the total recurrences of the homeopathic treated group was .41 per patient, while the antibiotic treatment group was .70 per patient. Of the "homeopathic" children who did have another earache, 29.3% had a maximum of three recurrences, while 43.5% of the "antibiotic" children had a maximum of six recurrences.

K.H. Friese, S. Kruse, H. Moeller; Biomedical Therapy, 60,4,1997:113-116 (Originally published

Page 36: Latest research in Homeopathy

Now, let us see some action of Homeopathic Medicines on Animals.

Page 37: Latest research in Homeopathy

Animal clinical studies: In a blinded study where rats were treated for urinary infections results showed that rats treated with homeopathic remedies had clear reduction of bacterial colonies. Results were at least as clear as for treatment with antibiotics. Untreated rats had no changes in bacteria colonies, compared to a reduction to 33 % of original bacteria levels in rats treated with antibiotics, and 22 % and 39 % in rats treated with homeopathic remedies (Phosphorus and self-nosode).Gonçalves et al. O uso da homeopatia no tratamento da infecção urinária

em ratas. Anais do VIII SINAPIH; 20-22 May, 2004: p.25-26.

Page 38: Latest research in Homeopathy

A study of homeopathically potentised remedies showed a reduction in the need for repetition of insemination and semen loss in treatment of fertilisation of female pigs. Riaucourt A. L´Exemple de la Filière Porcine. Annals of the “Entretiens Internationaux de Monaco 2002”, 5-6 October, 2002.

In a study of homeopathically potentised remedies the incidence of haematomas was reduced by 30 % in turkeys during transportation. The study was randomised, placebo controlled and double blinded. Filliat C. Particularité de l´utilisation de l´homéopathie en production avicole. Annals of the “Entretiens Internationaux de Monaco 2002”, 5-6 October 2002.

Page 39: Latest research in Homeopathy

Homeopathy versus conventional treatment in otitis media: Prospective observational study, comparision of Homeopathy versus conventional treatment in acute otitis media. Conclusion: Homeopathy should be first line treatment in acute otitis media. Results showed median duration of pain of 2 days in the homeopathy-group and 3 days in the conventional medicine group. 70.7 % of the children receiving homeopathic treatment did not have another ear infection the next year and 29.3 % had a maximum of three ear infections within one year. 56.5 % in the conventional medicine group did not have another ear infection the next year and 43.5 % had a maximum of six ear infections the next year. Results showed that in the group receiving homeopathic treatment only 5 out of 103 children needed antibiotics. Friese K-H, Kruse S, Ludtke R, Moeller H "Homeopathic treatment of otitis media in children: comparisons with conventional therapy". Int J Clin Pharmacol Ther. 1997; 35: 296-301.

Page 40: Latest research in Homeopathy

Recent, well-done studies on ECHINACEA show that it is not effective in preventing colds. However, in one study, 120 people with cold-like symptoms took 20 drops of echinacea every two hours for 10 days and had briefer colds than others.

http://www.webmd.com/cold-and-flu/cough08/cold-treatments Reviewed by Brunilda Nazario, MD on December 23, 2008

Page 41: Latest research in Homeopathy

Acute otitis media in children. In a trial of 230 children who were given homeopathic treatment to treat acute otitis media, pain control was achieved in 39% of the patients after 6 h and another 33% after 12 h. The resolution rates were 2.4 times faster than in placebo controls. No complications were observed and compared to conventional treatment the homeopathic approach was 14% cheaper. Frei H, Thurneysen A. Homeopathy in acute otitis media in children: treatment effect or spontaneous resolution? Br Homeopath J 2001; 90: 180–182.

Glue ear in children. In a pilot study in children suffering from glue ear treated with homeopathy 75% had normal tympanogram, compared to 31% in the group treated with conventional medicine. A higher proportion of children receiving home opathic treatment had a hearingloss less than 20 dB at follow-up, though the difference was not statistically significant. Harrison H, Fixsen A, Vickers A. A randomized comparison of homoeopathic, standard care for the treatment of glue ear in children. Compl Therap Med 1999; 7: 132–135.

Page 42: Latest research in Homeopathy

Polycystic Ovary Syndrome. 36 women suffering from Polycystic Ovary Syndrome (PCOS), and fitting the mental picture of the homoeopathic remedy Pulsatilla, were given Pulsatilla 6C, 4 hourly throughout the day for 2 weeks after the end of menstruation, and this was repeated for 4 consecutive cycles. At the end of the trial 30 of the 36 women had complete disappearance of the symptoms of PCOS and the production of normal ovulating follicles and a further 4 of the 36 became asymptomatic. Sanchez-Resendiz J., Guzman-Gomez F., Polycystic Ovary Syndrome. Boletin Mexicano de Homeopatica, 30, 1997, 11-15.

Page 43: Latest research in Homeopathy

Pre menstrual syndrome (PMS). In a randomized controlled double-blind clinical trial (1992-94) 19 women suffering from PMS were treated with individually with homeopathy. 90 % of the patients who had receieved homeopathic treatment experienced more than 30 % improvement. Only 37.5 % of patients who received placebo experienced a similar improvement. Sick-days before menses were reduced from 0.75 to 0 in the homeopathy-group, and was unchanged in the control group. Use of conventional drugs was also reduced in the homeopathy-group.

Yakir M, Kreitler S, Brzezinski A, Vithoulkas G, Oberbaum M, Bentwich Z. Effects of homeopathic treatment in women with premenstrual syndrome: a pilot study. Br Homeopath J. 2001 Jul ;90(3): 148-53.

Page 44: Latest research in Homeopathy

Homeopathy and oestrogen withdrawal. 40 out of 45 women with breast cancer withdrawing from oestrogen and then treated homeopathically, experienced significant improvement in their primary symptoms, anxiety and depression, as well as improvement in quality of life. Primary symptoms changed from 7.8 to 5.4, and from 7.2 to 4.1 (p<0.001). The homeopathic approach appears to be clinically useful in the management of oestrogen withdrawal symptoms in women with breast cancer. Thompson EA, Reilly D. The homeopathic approach to the treatment of symptoms of oestrogen withdrawal in breast cancer patients. A prospective observational study. Homeopathy. 2003 Jul;92(3):131-4.

Homeopathy in menopausal complaints. In a prospective study 82 % of 102 patients reported improvement of menopause symptoms after homeopathic treatment. Main symptoms noted were hot flushes and sweats, tiredness, anxiety, sleeping difficulties, mood swings and headaches. Women referred to homeopathy were those who either could not take hormone related treatment (HRT), for whom HRT was unsuccessful, who did not want or who had to come off HRT. Mean length of homeopathic treatment was 5 months. Relton, C. NHS Homeopathy Menopause Service. Outcome Study.

Page 45: Latest research in Homeopathy

Rheumatoid arthritis. Forty-six patients with rheumatoid arthritis received an individualised remedy or placebo in a 3-month randomised trial. Both groups were allowed to continue standard anti-inflammatory drugs. After 3 months, the double-blind code was broken and remedies were given to members of the placebo group in a single crossover study. Articular index, limbering up time, grip strength and pain all showed statistically significant differences. Gibson RG, Gibson SLM, MacNeill AD, Buchanan WW Homeopathic therapy in rheumatoid arthritis: evaluation by double-blind clinical therapeutic trial. British Journal of Clinical Pharmacology 1980; 9: 453-459.

Osteoarthritis. In this trial, 65 sufferers of Osteoarthritis (OA) were split into 2 groups, and through a double blinding process were given either a homoeopathic medicine or Acetaminophen, a commonly prescribed drug for pain relief in OA. Researchers found that homoeopathy provided a level of pain relief that was superior to Acetaminophen, and produced no adverse reactions. Shealy C.N., Thomlinson P.R., Cox R.H., and Bormeyer V. Osteoarthritis Pain: A Comparison of Homoeopathy and Acetaminophen. American Journal of Pain Management, 8, 3, July 1998, 89-91.

Page 46: Latest research in Homeopathy

Fibromyalgia. A double-blind, randomised, placebo-controlled trial of individualised homeopathic treatment (LM potency) versus placebo concluided that idividualised homeopathy is significantly better than placebo in lessening tender point pain and improving the quality of life and global health of persons with fibromyalgia. Bell IR, Lewis II DA, Brooks AJ, Schwartz GE, Lewis SE, Walsh BT, Baldwin CM. Improved clinical status in fibromyalgia patients treated with individualized homeopathic remedies versus placebo http://rheumatology. oupjournals.org/cgi/ reprint/keh111.

Fibrositis: In a randomised placebo-controlled trial of patients with fibrositis, only those patients in whom Rhus toxicodendron was ‘unequivocally indicated’ were admitted to the study. After 1 month’s treatment, the were highly significant improvements in objective and subjective parameters. Fisher P. An experimental double-blind clinical trial in homoeopathy. British Homoeopathic Journal 1986; 75: 142-147.

Page 47: Latest research in Homeopathy

Reduced labor time & complications: French researchers recently completed a double-blind trial using a homeopathic formula to treat pregnant women. the study found this homeopathic formula to reduce labor time and decrease abnormal labor. the average labor time of the women given the homeopathic formula was 5.1 hours, while the placebo group was 8.5 hours. only 11.3 percent of the women given the homeopathic formula had any abnormal labor, while 40 percent of the placebo group had an abnormal labor.Pierre Dorfman, Marie Noel Lasserre. and Max Tetau, "Preparation a l’accounchement par homeopathie: Experimentation en double-insu versus placebo" (Preparation for Birth by Homeopathy; Experimentation by Double-Blind Versus Placebo), Cahrs de Biotherapie. 94 (April 1987): 77-81.

Page 48: Latest research in Homeopathy

Dental Neuralgia: Another double-blind Homeopathy trial was conducted on patients with dental neuralgic pain following tooth extraction. An impressive 76 percent of those given the Homeopathic medicine Arnica and Hypericum experienced relief of pain.Henry Albertini et al.. "Homeopathic Treatment of Neuralgia Using Arnica and Hypericum: A Summary of 60 Observations," Journal of the American Institute of Homeopathy. 78 (September 1985): 126-128.

Vertigo & nausea: The respected GERMAN PHARMACOLOGICAL JOURNAL demonstrated a statistically significant improvement in REDUCING VERTIGO AND NAUSEA with a Homeopathic combination formula.C.F. Claussen, J. Bergmann. G. Bertora .and E. Claussen. "Homoopathische Kombinatlon bel Vertigo and Nausea." Arzneim. Forsch/Drug Res., 34(1984) 1791-98.

Page 49: Latest research in Homeopathy

A variety of surveys measuring patient satisfaction and improvement with homeopathy: A survey of more than 900 patients treated homeopathically showed substantial improvement in quality of life over the first 6 months after treatment and this effect remained more or less stable over the following years. Güthlin C, Lange O and Walach H. Measuring the effects of acupuncture and homoeopathy in general practice: An uncontrolled prospective documentation approach. BMC Public Health 2004, 4:6.

British prospective survey of homeopathic treatment of 223 patients, 1996. 90% improvement or more: 32%. 60% improvement or more: 65% 50% improvement or more: 72%. Report on NHS practice-based homoeopathy project. Analysis of effectiveness and cost of homoeopathic treatment within a GP practice at St. Margaret's Surgery, Bradford on Avon, Wilts. Elizabeth A Christie, Andrew T Ward ISBN 1 901262 006

Retrospective survey of homeopathic treatment, Danmarks Farmaceutiske Højskole, 1995. 73% of patients stated they improved after homeopathic treatment. Andersen HE, Eldov P. Klassisk hom?opati -og dens brugere. Institut for Samfundsfarmaci, Danmarks Farmaceutiske H?jskole. 1995. Andersen, Helle Egebjerg. En unders?gelse af Klassisk Homøpati. Teorier, praksis og brugererfaringer. 1999. ISBN 87-987279-0-7

Page 50: Latest research in Homeopathy

BASIC RESEARCHThermodynamics of extremely diluted aqueous solutions: An extensive thermodynamic study has been carried out on aqueous solutions obtained through successive dilutions and succussions of 1% in weight of some solutes up to extremely diluted solutions, (less than 1x10-5 mol kg-1) obtained via several 1/100 successive dilution processes. The interaction of acids or bases with the extremely diluted solutions has been studied calorimetrically at 25°C. Measurements have been performed of the heats of mixing of acid or basic solutions, having different concentrations, with bidistilled water or with the extremely diluted solutions. Despite the extreme dilution of the solutions, an exothermic heat of mixing in excess has been found, in about the 92% of the cases, with respect to the corresponding heat of mixing with the untreated solvent. Here [it is shown] that successive dilutions and succussions may alter permanently the physical-chemical properties of the solvent water. The nature of the phenomena here described still remains unexplained, but significant experimental results are obtained.Vittorio Elia and Marcella Niccoli; June 1, 1999; Annals of the New York Academy of Sciences, June 1999

Page 51: Latest research in Homeopathy

Can Biological Activity be Maintained at Ultra-high Dilution? An Overview of Homeopathy, Evidence and Bayesian Philosophy: The objective of this article is to critically review the major pieces of evidence on ultra-high dilution (UHD) effects and suggest how the scientific community should respond to its challenge. Such evidence has been conducted on a diverse range of assays -- immunologic, physiological, behavioral, biochemical, and clinical in the form of trials of homeopathic remedies. Evidence of UHD effects has attracted the attention of physicists who have speculated on their physical mechanisms. ...It is argued that if the phenomenon was uncontroversial, the evidence suffices to show that UHD effects exist. However, given that the observations contradict well-established theory, normal science has to be abandoned and scientists need to decide for themselves what the likelihood of UHD effects are. ...The difficulty in publishing high-quality UHD research in conventional journals prevents a fair assessment of UHD effects. Given that the existence of UHD effects would revolutionize science and medicine, and given the considerable empirical evidence of them, the philosophies of science tell us that possible UHD effects warrant serious investigation and serious attention by scientific journals.A.K. Vallance;The journal of Alternative and Complementary Medicine 1998 4:1;49-76

Page 52: Latest research in Homeopathy

Characterization of Differing Effects Caused by Homeopathically Prepared and Conventional Dilutions Using Cytochrome P450 2E1 and Other Enzymes as Detection Systems: Target of investigation was to ascertain differences in the effects of homeopathic potencies (D) and equally concentrated conventional dilutions (V) on p-nitrocatechol formation catalyzed by CYP 2E1. Arsenicum album and potassium cyanatum (D) were compared to equivalent dilutions of As203 and KCN (V). Significant differences in enzyme activity were found. The difference of influence exists and this may be attributable to the manufacturing process of homeopathic drugs, namely, the stepwise dilution with intermediate agitation.J. Dittmann and G. Harisch; The Journal of Alternative and Complementary Medicine 1996 2:2,279-290.

Transmission of Hormone Information by Non-molecular Means: This, and another study (The Effect of Highly Diluted Agitated Thyroxine on the Climbing Activity of Frogs), show that a homeopathic medicine can influence the growth and development of tadpoles in water. P.C. Endler, W. Pongratz, R. van Wijk, et al; FASEB Journal, 1994, 8, Abs.2313.

Page 53: Latest research in Homeopathy

Further Biological Effects Induced by Ultra High Dilutions: Inhibition by a Magnetic Field: This, and another study (Highly Dilute Antigen Increases Coronary Flow of Isolated Hart from Immunized Guinea-pigs), show that certain magnetic fields can neutralize the effects of a homeopathic medicine.J. Benveniste, P.C. Endler and J. Schulte, (eds.); Ultra High Dilution Dordrecht: Kluwer Academic, 1994, 35.

The Effect of Highly Diluted Agitated Thyroxine on the Climbing Activity of Frogs: This, and another study (Transmission of Hormone Information by Non-molecular Means), show that a homeopathic medicine can influence the growth and development of tadpoles in water. P.C. Endler, W. Pongratz, G. Kastberg, et al; Veterinary and Human Toxicology, 1994, 36:56.

Highly Dilute Antigen Increases Coronary Flow of Isolated Heart from Immunized Guinea-pigs: This, and the other study (Further Biological Effects Induced by Ultra High Dilutions), show that certain magnetic fields can neutralize the effects of a homeopathic medicine. J. Benveniste, B. Arnoux, L. Hadji; FASEB Journal, 1992, 6:Abs.1610.

Page 54: Latest research in Homeopathy

Effect on Mouse Peritoneal Macrophages of Orally Administered Very High Dilutions of Silica: This study showed Silica 6C and Silica 10C induced a statistically significant increase in immune function, as measured in macrophages in the blood of mice. E. Davenas, B. Poitevin, and J. Benveniste; European Journal of Pharmacology, April, 1987, 135:313-319.

ANTIVIRAL: A recent double-blinded study has shown the antiviral effect of homeopathic remedies eight of the ten remedies tested inhibited viruses in chicken embryos from 50 to 100 percent depending on the potencies used. L.M. Singh and G. Gupta, "Antiviral Efficacy of Homeopathic Drugs Against Animal Viruses," British Homeopathic Journal, 74 (July 1985): 168-174.

HEAVY METALS: The respected journal. Human Toxicology. published a study showing that Homeopathic doses of arsenic eliminated crude doses of trapped arsenic that had been previously fed to rats.J.C. Cazin et al.. "A Study of the Effect of Decimal and Centesimal Dilution of Arsenic on Retention and Mobilization of Arsenic in the Rat," Human Toxicology, July 1987.

Page 55: Latest research in Homeopathy

LOWERED SERUM CHOLESTEROL: Four german scientists at a veterinary college showed that Homeopathic chelidonium had lowered serum cholesterol when given twice a day to rabbits on a cholesterol rich diet.V. Baumans, C.J. Bol, W.M.T. oWe Luttikhuis, and A.C. Beynen. "Does Chelidonium 3X Lower Serum Cholesterol?" British Homeopathic Journal, 76 (January 1987): 14-15.

REDUCED LABOR PROBLEMS: British Veterinarian, Christopher Day, had conducted several pilot studies demonstrating how Homeopathic Remedies had reduced labor problems in cattle. still births in pigs, and mastitis in catlle.Christopher Day, "Control of Stillbirths in Pigs Using Homeopathy." Veterinary Record, 114 (March 3, 1984): 216 reprinted in American Institute of Homeopathy, 779 (December 1986): 146-147. Christopher Day, "Clinical Trials in Bovine Mastitis: Use of Nosodes for Prevention," British Homeopathic Journal, 75 (January 1986): 11-15.

ANTI-CANCER: The Cancer Research Center in India found that of the 77 mice That received a transplant in fibrosarcoma, 52 percent survived more than one year with Homeopathic Remedies. The 77 mice That were untreated died within 10-15 days.H. Choudhury, "Cure of Cancer in Experimental Mice with Certain Biochemic Salts," British Homeopathic Journal, 69 (1980): 168-170.

Page 56: Latest research in Homeopathy

PAIN CONTROL: Scientists at a British SchooL of Pharmacy found that rodents given Hypericum were able to inhibit pain responses. Rodents were able to remain on a hot plate longer than the control group. When given NaLoxone. which inhibits pain killing endorphins, the protective effects of Hypericum was reduced, showing that Homeopathic Hypericum activates endorphins when needed. Please note that these rodents were free to walk off the hot plate whenever discomfort was noticed.G.R. Keysall, K.L. Williamson, and B.D. Tolman. "The Testing of Some Homeopathic Preparations in Rodents, "Proceedings of the 40th International Homeopathic Congress (Lyon. France, 1985). pp. 228-231

ALLERGIES: Homeopathic Apis and Histamine have a significant effect on reducing the release of certain allergy-causing chemicals from Basophils, which demonstrates one reason for Homeopathy’s positive effects on allergies.Jean Boiron. Jacky Abecassls. and Philippe Belon. "The Effects of Hahnemannian Potencies of 7c Histaminum and 7c Apis Mellifica upon Basophil Degranulation in Allergic Patients." Aspects of Research in Homoepathy (Lyon: Boiron, 1983), pp. 61-66.

DELAYED MICE INTOXICATION: A controlled experiment on mice intoxicated with alcohol, has shown that giving mice Nux vomica 30 reduced the time between getting intoxicated and righting themselves by 44%. This experiment was double blind and fulfilled all criteria expected of such experiments. (Sukul A, Sinhabau SP and Sukul NC. Reduction of alcohol induced sleep time in albino mice by potentized Nux vomica prepared with 90% ethanol. Br Homoeopath J. 88: 58-61. 1999.)

Page 57: Latest research in Homeopathy

MALT DIASTASE: The pioneering work of Boyd bound the worlds of homoeopathy and Arndt-Schulz together in the early 1940s with a series of tightly controlled experiments, and set the stage for work much later on as to how homoeopathic medicine may work. Boyd worked with the enzyme malt diastase, which was already known to be inhibited by crude doses of the salt mercuric chloride, and measured its speed in the hydrolysis of starch. He also used a number of homoeopathically prepared dilutions of mercuric chloride, including a batch at 61x, where there was no likelihood of any of the original salt remaining - it was pure water. He also worked with distilled water as a control. He showed that crude doses of mercuric chloride inhibited diastase activity, as was already well known, and that distilled water had no effect. But he also showed, with statistically significant results, that mercuric chloride 61x accelerated diastase activity. Boyd: The Action of Microdoses of Mercuric Chloride on Malt Diastase. Brit Hom J; 31; 1-28 (1941) and 32; 106-111 (1942)

Page 58: Latest research in Homeopathy
Page 59: Latest research in Homeopathy

LABORATORY EVIDENCE — The number one criticism of the scientific community has been the "infinitesimal" nature or the dilution principle of Homeopathy. Homeopaths do agree that once a remedy is diluted beyond 24x or 12C potencies they are diluted beyond Avagadro's Number (6.23 x 10-23) which theoretically indicates that no molecules are present in the original substance. However, both LABORATORY AND CLINICAL RESULTS over The last 190 years have demonstrated definite effectiveness with Homeopathic remedies beyond this dilution. A recent NUCLEAR MAGNETIC RESONANCE (NMR) study showed that all twenty-three different Homeopathic Remedies and Potencies tested had DISTINCTIVE READINGS OF SUBMOLECULAR ACTIVITY, while The Placebos did not. This demonstrates That homeopathy's function is not so much chemical but energetic. As Chiropractors, you will observe dramatic clearing of sensory nerve Interference and pathological reflex activity causing chronic recurring subluxation activity and dis-ease. Adam Sacks. "Nuclear Magnetic Resonance Spectroscopy of Homeopathic Remedies," Journal of Holistic Medicine, 5 (Fall-Winter 1983): 172-175: RB. Smith and G.W. Boericke, "Changes Caused By Succussion on N.M.R, Patterns and Bioassay of Bradykinin Triacetate (BKTA) Succussions and Dilution Journal of The American Institute of Homeopathy, 61 (November-December 1968): 197-212.

Page 60: Latest research in Homeopathy

ECONOMETRICUse of complementary and alternative medicine in a general pediatric clinic: This study looked at CAM usage by a population of parents attending a pediatric outpatient clinic at a university-affiliated general hospital in Quebec, Canada over a four week period (Jean, 2007). CAM therapies included chiropractic, naturopathy, homeopathy, massage, acupuncture, Reiki/energy care, hypnosis, osteopathic manipulation, folk remedies, and any hands-on techniques to promote health. A total of 114 children were included in the study, and 54 percent of these children had received CAM care, a higher number than reported in previous studies. The most popular forms of treatment were homeopathy, chiropractic, and naturopathy, all of which we would define as holistic systems of pediatric care. It is interesting that 39 percent of these families had sought homeopathic care for their child, a higher figure than in most other studies. The fact that most of these children presented to this clinic for chronic problems may explain the high level of holistic care and the high level of homeopathic care in this population.Jean D, Cyr C. Use of complementary and alternative medicine in a general pediatric clinic. Pediatrics. July 2007; 120 (1):e138-e141. 

Page 61: Latest research in Homeopathy

Charges, utilization, and practice patterns from a pilot insurance program covering alternative medical services: Study conducted in Seattle, WA which compared the utilization and cost of homeopathic, naturopathic, and acupuncture services. Researchers concluded that homeopathic care was the least costly and that patient visits to homeopaths were less often than to other alternative care professionals. (This study, however, did not compare utilization or costs against conventional medical care). Jacobs, J, Smith, N.; American Public Health Association Conference, New York City, November 18-21, 1996.

Cost-effectiveness of homeopathic treatment in a dental practice: This study evaluated a single homeopathic dentist's practice and suggested that it was more cost-effective than conventional dental care. British Homoeopathic Journal. January, 1993;82,1:22-28

Page 62: Latest research in Homeopathy

Caisse Nationale de l'Assurance Maladie des Travailleurs Salaris (January 1, 1996): A study of 130,000 prescriptions confirmed the results of the 1991 French Government Report: Social Security Statistics: Conducted by the French government in 1991, this study showed a significantly reduced cost from homeopathic care versus conventional medical care. The totality of costs associated with homeopathic care per physician was approximately one-half of the totality of care provided by conventional primary care physicians. However, because homeopathic physicians, on average, saw significantly fewer patients, the overall cost per patient under homeopathic care was still a significant 15% less. It is also appeared that these savings increase the longer a physician has been using homeopathy.CNAM (National Inter-Regulations System) 61, January 1991.

Page 63: Latest research in Homeopathy

LATEST DEVELOPMENT IN THE FIELD OF MODERN MEDICINEThe so-called Modern Medicine obviously doesn’t have any law, which governs their line of treatment. One they propose some line of treatment the other day they find it wrong. Here are a few examples:Delaying DPT Vaccination may reduce incidence of childhood asthma- Laurie Barclay, MDChildhood asthma is reduced by half when the first dose of diphtheria, pertussis, and tetanus (DPT) is delayed by more than 2 months vs given during the recommended period, according to the results of a retrospective longitudinal study reported in the March issue of the Journal of Allergy & Clinical Immunology.Among 11,531 children who received at least 4 doses of DPT, the risk for asthma was halved in children in whom administration of the first dose of DPT was delayed by more than 2 months. For children with delays in administration of all 3 doses, the likelihood of asthma was 0.39 (95% confidence interval [CI], 0.18 - 0.86).

Page 64: Latest research in Homeopathy

Conclusion:Among children who received at least 4 doses of DPT, the risk for asthma was reduced by 50% in children in whom administration of the first dose of DPT was delayed by more than 2 months from the recommended period. For children with delays in administration of all 3 doses of DPT, the risk of developing asthma was decreased by 60%. The reduction in asthma risk for the second and third doses mainly resulted from the delay in the first dose.

Homeopathic Comment: A lot has been said about the possible hazards of vaccination in Homoeopathic literature & the theory of suppression. The above study is the acceptance of proposition of Dr.Hahnemann.

DPT Molecule

Page 65: Latest research in Homeopathy

Nonoperative Treatment of Osteoporotic Compression:Concerns have been raised over posterior spinal stress resulting from the employment of extension bracing in patients with osteoporotic vertebral compression fractures. In addition, research indicates that the use of vertebroplasty and kyphoplasty in the treatment of such fractures can increase the risk of adjacent vertebral body fractures. Therefore, conservative treatment should be the choice of treatment.Grant Cooper, MD The University Hospitals of Columbia and Cornell; Julie Lin, MD Weill Medical College of Cornell University Joseph M Lane, MD Weill Medical College of Cornell University

Anticoagulation treatment shows no improvement (Cardio embolic Stroke)(Michael J Schneck, MD Loyola University Chicago Lei Xu, MD, PhD Loyola University Chicago)

A meta-analysis indicates that in patients with acute cardioembolic stroke, early anticoagulation treatment is not associated with improved outcomes.

Page 66: Latest research in Homeopathy

Shingles Linked to Family History of Herpes Zoster Hien T. Nghiem, MD

May 20, 2008 — There is an association between shingles and a family history of herpes zoster (HZ), according to the results of a case-control study reported in the May issue of Archives of Dermatology.

Homeopathic Comment: Transfer of Miasm from parents to their offsprings / to next generation has been proposed in the theory of Miasms.

Depressive Conditions Linked to Asthma Severity Laurie Barclay, MD

May 16, 2008 — Depressive conditions reported by both patients and their primary care physicians are associated with increased asthma severity, according to a report in the May issue of Chest.

Homeopathic Comment: SOMATIC DISEASES OF PSYCHOLOGICAL ORIGIN A variety of diseases including peptic ulcer have been identified to be of Psychological origin (Psycho-somatic) which was previously believed to be purely somatic by Modern Medicine. Importance of mental symptoms & mental causations in origin of somatic disease has been off late accepted.

Page 67: Latest research in Homeopathy

The Modern Medicine researches are market driven & profit generating gimmicks. There is nothing called good sense that prevails on them & hence the so-called most effective medicine turns out to be a disaster & is subsequently banned. Is there anyone who questions their scientificity? The Thalidomide Disaster 1977Friday, Aug. 10, 1962 Appalling reports continued to roll in. So far as is known, close to 8,000 babies have been born deformed (who should be held responsible) because their mothers used a sleeping-pill-tranquilizer called thalidomide (TIME, Feb. 23). All this added up to the greatest prescription disaster in medical history.

Page 68: Latest research in Homeopathy

§ 64- During the primary action of the artificial morbific agents (medicines) on our healthy body, as seen in the following examples, our vital force seems to conduct itself merely in a passive (receptive) manner, and appears, so to say, compelled to permit the impressions of the artificial power acting from without to take place in it and thereby after its state of health; it then, however, appears to rouse itself again, as it were, and to develop (A) the exact opposite condition of health (counteraction, secondary action ) to this effect (primary action) produced upon it, if there be such an opposite, and that in as great a degree as was the effect (primary action) of the artificial morbific agent on it, and proportionate to its own energy; - or (B) if there be not in nature a state exactly the opposite of the primary action, it appears to endeavor to indifferentiate itself, that is, to make its superior power available in the extinction of the change wrought in it from without (by the medicine), in the place of which it substitutes its normal state (secondary action, curative action).

Page 69: Latest research in Homeopathy

Proton-Pump Inhibitor Withdrawal May Cause Rebound Acid Hypersecretion CME/CE

News Author: Laurie Barclay, MDCME Author: Laurie Barclay, MD

July 6, 2009 — Proton-pump inhibitor (PPI) therapy for 8 weeks induces acid-related symptoms in healthy volunteers after withdrawal, according to the results of a randomized, double-blind, placebo-controlled trial reported in the July issue of Gastroenterology."Rebound acid hypersecretionRebound acid hypersecretion (RAHS) has been demonstrated after 8 weeks of treatment with a proton-pump inhibitor (PPI)," write Christina Reimer, from Køge University Hospital, Copenhagen University in Copenhagen, Denmark, and colleagues. "If RAHS induces acid-related symptoms, this might lead to PPI dependency and thus have important implications.“http://cme.medscape.com/viewarticle/705250?src=cmenews

Page 70: Latest research in Homeopathy

THESE VERY COMMONLY USED DRUGS HAVE BEEN GLOBALLY BANNED:ANALGIN: This is a pain-killer. Reason for ban: Bone marrow depression.   CISAPRIDE: Acidity, constipation. Reason for ban: irregular heartbeatDROPERIDOL: Anti-depressant. Reason for ban: Irregular heartbeat. FURAZOLIDONE: Antidiarrhoeal. Reason for ban: Cancer. NIMESULIDE: Painkiller, fever. Reason for ban: Liver failure.   NITROFURAZONE: Antibacterial cream. Reason for ban: Cancer.   PHENOLPHTHALEIN:   Laxative. Reason for ban: Cancer.   PHENYLPROPANOLAMINE: cold and cough. Reason for ban: stroke. OXYPHENBUTAZONE:   Non-steroidal anti-inflammatory drug. Reason for ban: Bone marrow depression.   PIPERAZINE:   Anti-worms. Reason for ban: Nerve damage. QUINIODOCHLOR:   Anti-diarrhoeal. Reason for ban: Damage to sight.

Page 72: Latest research in Homeopathy

I think, I have done my job. Right!

Page 73: Latest research in Homeopathy

DR.K.M.NISANTH & DR.SMITA NISANTH

An ordinary teacher teaches, good An ordinary teacher teaches, good teacher demonstrates, an excellent teacher demonstrates, an excellent

teacher inspires.teacher inspires.

Page 74: Latest research in Homeopathy

www.nambisons.com , www.diagnozit.com

Page 76: Latest research in Homeopathy

DIP YOURSELF IN THE high TEA

www.nambisons.com , www.diagnozit.com