Last Updated 11/04/2021 Page: 2

TCT 2021

Last Updated 11/04/2021 Page: 2

THURSDAY, NOVEMBER 04, 2021 3 - Structural Heart Disease #1 - Columbia University Medical Center, New York City, NY 3 - Structural Heart Disease #2 - Erasmus University-Thoraxcenter, Rotterdam, the Netherlands 3 - Coronary #1 - Mount Sinai Medical Center, New York City, NY 3 - Coronary #2 - Columbia University Medical Center, New York City, NY 3 - TCT 2021 Thomas J. Linnemeier Spirit of Interventional Cardiology Young Investigator Award – Astonishing Group 4 - Hot Topic: Controversies From ESC & ACC/AHA – Valvular Heart Disease Guidelines 4 - Structural Heart Disease #3 - Mount Sinai Medical Center, New York City, NY - LAAO 5 - Structural Heart Disease #4 - Columbia University Medical Center, New York City, NY 5 - Coronary #3 - Mount Sinai Medical Center, New York City, NY 5 - Structural Heart Disease #5 - Erasmus University-Thoraxcenter, Rotterdam, the Netherlands 5 - Satellite: Clinical Science to Landmark Trials of LV Unloading in HR-PCI and CS 6 - Coronary Hot Topic #1: Revascularization Decisions in Chronic Coronary Syndromes, Part 1 6 - Coronary Hot Topic #1: Revascularization Decisions in Chronic Coronary Syndromes, Part 2 6 - Structural Hot Topic #1: Two Deep Dives – Bicuspids and Bioprosthetic Valve Failure, Part 1 7 - Structural Hot Topic #1: Two Deep Dives – Bicuspids and Bioprosthetic Valve Failure, Part 2 7 - Late-Breaking Clinical Trials Session I, In Collaboration With Lancet 7 - Late-Breaking Clinical Science Session I, In Collaboration With Circulation 8 - Special Hot Topic Session: COVID Vaccine Update 8 - Coronary Hot Topic #2 & #3: LM and Bifurcation Essentials – From Evidence to Experience 8 - Structural Hot Topic #3: Two Deep Dives – Tricuspid Leaflet Grasping and Replacement Therapies, Part 1 9 - Structural Hot Topic #3: Two Deep Dives – Tricuspid Leaflet Grasping and Replacement Therapies, Part 2 9 - Coronary Hot Topic #4: The Challenges of Complex Lesions – A Case-Based Problem-Oriented Symposium, Part 1, Supported through Unrestricted Educational Grants from Medtronic and Boston Scientific Corporation 10 - Coronary Hot Topic #4: The Challenges of Complex Lesions – A Case-Based Problem-Oriented Symposium, Part 2, Supported through Unrestricted Educational Grants From Medtronic and Boston Scientific Corporation 10 - Satellite: Coronary DCB: The European Standard and Still Not in the U.S. Toolbox? Why, When and How? 10 - Featured Clinical Research Session I 11 - Structural Hot Topic #2: Expanding Vision of Transcatheter Tricuspid Valve Therapies 11 - TCT Shark Tank 12 - FDA Town Hall Session I: Impact of COVID-19 12 - FDA Town Hall Session II: Responding to a Black Swan Event 12 - FDA Town Hall Session III: Pragmatic Clinical Trials 12 - Emerging Technological Trends I: Transcatheter Mitral & Tricuspid Technologies - Part I 13 - Emerging Technological Trends I: Transcatheter Mitral & Tricuspid Technologies - Part 2 13 - What’s Novel in Interventional Hypertension 14 - Best of Abstracts 14 - Satellite: Ability to beat diabetes globally with an innovative DES+DCB platform 15 - Satellite: Optimizing Outcomes in Calcific Cardiovascular Disease: Real-World Techniques with the Diamondback 360® Orbital Atherectomy System 15 - Satellite: Novel Technologies for Interventional Guidance – 4D ICE, Fusion, and Holograms 15 - Innovation at TCT World Connect: LAA Occlusion and Cerebral Protection Sponsored by CRF 16 - Satellite: Small Annulus, Big Clinical Benefits? 16 - Satellite: Ultra-low contrast PCI case studies in high-risk patients: Techniques and tools to optimize outcomes THURSDAY, NOVEMBER 04, 2021 16 - Aortic Stenosis, Aortic Insufficiency, and TAVR I 16 - Imaging and Physiology I 17 - SCAD and Non-Atherosclerotic Causes of MI 17 - PCI and PCI Outcomes I 17 - CTO Intervention 18 - ACS, STEMI, and Cardiogenic Shock 18 - Artificial Intelligence and Deep Learning 18 - COVID-19 19 - Aortic Aneurysm and Dissection 19 - Ventricular Remodeling and Septal Closure 19 - Mitral Valve Disease and Intervention I 20 - Mitral Valve Disease and Intervention II 20 - Aortic Valve Disease and Intervention I 20 - Aortic Valve Disease and Intervention II 20 - Cardiogenic Shock and Hemodynamic Support 21 - Left Atrial Appendage 21 - Networking Reception 21 - Industry Hub 22 - Virtual Exhibit Hall FRIDAY, NOVEMBER 05, 2021 22 - Structural Heart Disease #6 - Emory University, Atlanta, GA 22 - Coronary #4 - Royal Victoria Hospital, Belfast, Northern Ireland 22 - Coronary #5 - Royal Victoria Hospital, Belfast, Northern Ireland 22 - Coronary #6 - Emory University, Atlanta, GA 22 - TCT 2021 Thomas J. Linnemeier Spirit of Interventional Cardiology Young Investigator Award – Extraordinary Group 23 - Hot Topic: How to Get Better as an Interventionalist – Learning From Complications, Supported through Unrestricted Educational Grants From Medtronic and Boston Scientific Corporation 23 - Hot Topic: Revascularization Guidelines – From “Certainty" (Class I and III) to "Probability" (Class II); Where Are the Gaps? 23 - Coronary #7 - University of Washington, Seattle, WA 24 - Coronary #8 - Humanitas Medical Center, Milan, Italy, This live case is sponsored by CRF and supported through unrestricted educational grants from Alvimedica and Concept Medical 24 - Structural Heart Disease #7 - Emory University, Atlanta, GA 24 - Structural Heart Disease #8 - University of Washington, Seattle, WA 24 - Coronary Hot Topic #5: CTO Essentials – Pathway and Tips and Tricks for Success, Part 1 24 - Coronary Hot Topic #5: CTO Essentials – Pathway and Tips and Tricks for Success, Part 2 25 - Structural Hot Topic #5: Mitral Transcatheter Edge-to-Edge Repair (TEER) – Clinical Insights and Controversies 25 - Late-Breaking Clinical Trials Session II, In Collaboration With JAMA 26 - Late-Breaking Clinical Science Session II, In Collaboration With The European Heart Journal 26 - Coronary Hot Topic #7: Outstanding Issues in STEMI Management – MV Disease, Myocardial Salvage, and More, Part 1 26 - Coronary Hot Topic #7: Outstanding Issues in STEMI Management – MV Disease, Myocardial Salvage, and More, Part 2 27 - Structural Hot Topic #4: TAVR Lifelong Management Journey With Aortic Stenosis 27 - Structural Hot Topic #7: TAVR – Knowledge Gaps, Controversies, and Unresolved Issues, Part 1 27 - Structural Hot Topic #7: TAVR – Knowledge Gaps, Controversies, and Unresolved Issues, Part 2 28 - Coronary Hot Topic #8: Balancing the Full Spectrum of Bleeding and Ischemic Risk in PCI, Part 1 28 - Coronary Hot Topic #8: Balancing the Full Spectrum of Bleeding and Ischemic Risk in PCI, Part 2 28 - Satellite: A Heart Team Walks Into a Conference Room... 29 - Featured Clinical Research Session II 29 - SCAI at TCT: New Directions in Cardiogenic Shock 29 - Coronary Hot Topic #6: Cardiogenic Shock and Cardiac Arrest Revisited 30 - Emerging Technological Trends II: Cath Lab of the Future and Emerging PCI Tools 30 - FDA Town Hall Session IV: Tricuspid Valve Interventions 30 - FDA Town Hall Session V: Heart Failure Interventions 31 - FDA Town Hall Session VI: Left Atrial Appendage Interventions 31 - FDA Town Hall Session VII: Digital Health Apps 31 - Emerging Technological Trends III: Interventional Heart Failure and Neuromodulation Therapies 32 - Structural Hot Topic #6: Mitral Valve Repair – Beyond Leaflet Grasping 32 - Structural Hot Topic #8: TMVR (Replacement) – Current Clinical Indications, Potential Technical Advantages, and Limitations 32 - Best of Challenging Cases 33 - Satellite: Advancing Coronary Intervention with Sirolimus-Coated Balloons 33 - Satellite: Advanced PCI Techniques in Real World Cases 34 - Satellite: Advancing the Future of Intracardiac Echo in Structural Heart Disease Procedures 34 - Satellite: New Insights on the Consistency of Coronary IVL Data 34 - Satellite: Coronary Aspiration in 2021: Results of the Cheetah Study 34 - Satellite: Transforming Hypertension Treatment: Updates on MEDTRONIC's SPYRAL-HTN Global Clinical Trial Program 35 - Innovation @ TCT World Connect: Innovation Trends in TAVR Technologies, Sponsored by CRF 35 - Satellite: Balancing Ischemic and Bleeding Risk with Antiplatelet Therapy: Personalizing Treatment to Optimize Outcomes 35 - Satellite: Real-world, Lytic-free Evidence for Treatment of Pulmonary Embolism with Inari Medical’s FlowTriever 36 - Aortic Stenosis, Aortic Insufficiency, and TAVR II

36 - Mitral Disease and Intervention 37 - Tricuspid Valve Disease and Intervention 37 - TVT Registry Studies 37 - Plaque Modification 38 - Left Main and Bifurcation Disease and Intrervention 38 - Endovascular Diseases and Intervention 39 - Antiplatelet and Antithrombotic Drug Studies 39 - Endovascular Diseases and Intervention I 39 - Endovascular Diseases and Intervention II 40 - Left Main and Bifurcation Intervention 40 - CTO I 40 - CTO II 41 - Unusual PCI Cases I 41 - Unusual PCI Cases II 41 - Aortic and Tricuspid Valve Disease and Intervention 42 - Industry Hub 42 - Virtual Exhibit Hall SATURDAY, NOVEMBER 06, 2021 42 - Structural Heart Disease #9 - Cedars-Sinai Medical Center, Los Angeles, CA 42 - Coronary #9 - Abbott Northwestern, Minneapolis, MN 42 - Coronary #10 - Humanitas Medical Center, Milan, Italy, This live case is sponsored by CRF and supported through unrestricted educational grants from Alvimedica and Concept Medical. 43 - Structural Heart Disease #10 - Abbott Northwestern, Minneapolis, MN 43 - Award Presentation: Shark Tank 43 - Hot Topic: PCI Bleeding Avoidance Strategies – Expert Case Management 43 - Coronary #11 - University Heart Center, Bad Krozingen, Germany 44 - Coronary #12 - University Heart Center, Bad Krozingen, Germany 44 - Structural Heart Disease #11 - Cedars-Sinai Medical Center, Los Angeles, CA 44 - Structural Heart Disease #12 - Abbott Northwestern, Minneapolis, MN 44 - CME Satellite: Latest in Transcatheter Repair Therapies for Mitral Regurgitation: TEER, Annuloplasty& Chordal Repair (Available in person and on demand only) 45 - Coronary Hot Topic #9: Case-Based Physiology Assessment and Procedural Guidance 45 - Structural Hot Topic #9: Two Deep Dives – Mitral Imaging and Case Studies in Mitral Valve Disease, Part 1 46 - Structural Hot Topic #9: Two Deep Dives – Mitral Imaging and Case Studies in Mitral Valve Disease, Part 2 46 - Late-Breaking Clinical Trials Session III, In Collaboration With JACC 47 - Late-Breaking Clinical Science Session III 47 - Structural Hot Topic #10: TAVR Hot Topic – Valve Hemodynamics and PPM Assessment 48 - Structural Hot Topic #11: Left Atrial Appendage Closure, Part 1 48 - Structural Hot Topic #11: Left Atrial Appendage Closure, Part 2 49 - Coronary Hot Topic #12: Intravascular Imaging Using IVUS and OCT – A Case-Based Direct Comparison 49 - Structural Hot Topic #12: PFO Closure – Concepts and Controversies 50 - Satellite: Transforming Hypertension Treatment: From Evidence to Consensus to Action 50 - Coronary Hot Topic #10: SCAD, MINOCA, INOCA, Takotsubo Syndrome 51 - Coronary Hot Topic #11: New Directions: From ISCHEMIA to Vulnerable Plaque 51 - Interventional Heart Failure 1: Overview 52 - Interventional Heart Failure 2: Acute Decompensated Heart Failure 52 - Interventional Heart Failure 3: Patient Monitoring 53 - Endovascular Featured Clinical Research 53 - Endovascular: Lower Extremity PAD State-of-the-art 53 - Endovascular: CLI 54 - Endovascular: Pulmonary Embolism – Controversies and Crossroads 54 - Featured Clinical Research Session III 55 - Satellite: The Conundrum of Managing Chronic Coronary Disease: DPI or DAPT? 55 - Satellite: Sirolimus Coated Balloon: What the FUTURE holds for PAD 56 - Satellite: Master The Complex 56 - Satellite: Smith Center Symposium on Intravascular Ultrasound for Lower Extremity Arterial and Venous Intervention 57 - Satellite: Advancing the Treatment of Uncontrolled Hypertension with Ultrasound RDN 57 - Satellite: Pulmonary Artery Denervation for Pulmonary Hypertension 57 - Satellite: Intrepid TMVR Early Experiences 58 - Satellite: Leading with evidence, choosing with confidence -TARGET Release, It Works 58 - Aortic Stenosis, Aortic Insufficiency, and TAVR III 59 - Imaging and Physiology II 59 - Structural Heart Disease and Intervention 59 - LAA Closure 60 - PCI and PCI Outcomes II 60 - Pulmonary Vascular Diseases 61 - PCI Complications 61 - Plaque Modification and Lithotripsy 61 - ACS, NSTEMI, and STEMI 62 - Industry Hub 62 - Virtual Exhibit Hall

TCT 2021 | THURSDAY, NOVEMBER 04, 2021


THURSDAY, NOVEMBER 04, 2021 - _

Structural Heart Disease #1 - Columbia University Medical Center, New York City, NY

Live Cases Structural: Valve _

Live Case Theater

THURSDAY, NOVEMBER 04, 2021 8:00 AM - 8:55 AM

This session is CME/MOC accredited.

8:00 AM - 8:55 AM

Structural Heart Disease #1 - Columbia University Medical Center, New York City, NY Live Case Moderators: Martin B. Leon Live Case Co-Moderators: Michael J. Mack Live Case Discussants: Anita W. Asgar, João L. Cavalcante, Charles J. Davidson, Sammy Elmariah Live Case Operators: Isaac George, Rebecca T. Hahn, Susheel K. Kodali

8:00_AM Structural Heart Disease #1 - Columbia University Medical Center, New York City, NY

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Structural Heart Disease #2 - Erasmus University-Thoraxcenter, Rotterdam, the Netherlands


Live Case Theater



9:00 AM - 10:00 AM

Structural Heart Disease #2 - Erasmus University-Thoraxcenter, Rotterdam, the Netherlands Live Case Moderators: Eberhard Grube Live Case Co-Moderators: Lars Sondergaard Live Case Discussants: Alexandre Abizaid, Kendra J. Grubb, Julia Seeger, Corrado Tamburino Live Case Operators: Joost Daemen, Wijnand Den Dekker, Roberto Diletti, Nicolas M. Van Mieghem, Jeroen M. Wilschut

9:00_AM Live Case Introduction of Structural Heart Disease #2 - Erasmus University-Thoraxcenter, Rotterdam, the Netherlands

Moderator: Martin B. Leon

9:05_AM Structural Heart Disease #2 - Erasmus University-Thoraxcenter, Rotterdam, the Netherlands

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Coronary #1 - Mount Sinai Medical Center, New York City, NY

Coronary: CHIP Coronary: Core Live Cases _

Live Case Theater



10:00 AM - 10:55 AM

Coronary #1 - Mount Sinai Medical Center, New York City, NY Live Case Moderators: Gregg W. Stone Live Case Co-Moderators: William W. O'Neill Live Case Discussants: Itsik Ben-Dor, Donald Cutlip, William F. Fearon Virtual Live Case Discussants: Kathleen Kearney Live Case Operators: Annapoorna Kini, Samin K. Sharma

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Coronary #2 - Columbia University Medical Center, New York City, NY


Live Case Theater



10:55 AM - 11:50 AM

Coronary #2 - Columbia University Medical Center, New York City, NY Live Case Moderators: Paul S. Teirstein Live Case Co-Moderators: Gary S. Mintz Live Case Discussants: Bruno Scheller Virtual Live Case Discussants: Alexandre Abizaid, Mirvat Alasnag, David A. Cox Live Case Operators: Ajay J. Kirtane, Akiko Maehara, Jeffrey W. Moses

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TCT 2021 Thomas J. Linnemeier Spirit of Interventional Cardiology Young Investigator Award – Astonishing Group

Live Case Theater

THURSDAY, NOVEMBER 04, 2021 1:00 PM - 1:15 PM

This session is not accredited.

1:00 PM - 1:15 PM

TCT 2021 Thomas J. Linnemeier Spirit of Interventional Cardiology Young Investigator Award – Astonishing Group



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Hot Topic: Controversies From ESC & ACC/AHA – Valvular Heart Disease Guidelines

Live Case Theater



1:15 PM - 2:45 PM

Controversies in the Management of Valvular Heart Disease – Beyond Guidelines

1:15_PM Introduction and Objectives Intro/ Closing Presenter: Bernard Prendergast

1:17_PM Guidelines – What They Are And What They Are Not Lecturer: Robert O. Bonow

1:24_PM Beyond Guidelines – Novel Approaches to Achieve Evidence-Based Practice

Virtual Lecturer: Catherine M. Otto 1:31_PM Case Scenarios

65-Year-Old With Severe AS And Bicuspid Valve - SAVR or TAVI? Virtual Moderators: Patrick T. O'Gara Discussants: John K. Forrest, Stephen H. Little, Michael J. Reardon, Hendrik Treede

1:31_PM Case Presentation: 65-Year-Old With Severe AS And Bicuspid Valve - SAVR or TAVI?

Case Presenter: Karim Al-Azizi*

1:35_PM What the Guidelines Say Virtual Lecturer: Vera Rigolin

1:40_PM What the Heart Team Says Discussant: John K. Forrest, Stephen H.

Little, Michael J. Reardon, Hendrik Treede

1:46_PM Case Outcome Case Presenter: Karim Al-Azizi*

75-Year-Old With Severe AS And Proximal LAD Stenosis - TAVI Alone, TAVI Plus PCI or SAVR Plus CABG? Virtual Moderators: Bernard Prendergast Discussants: John K. Forrest, Stephen H. Little, Michael J. Reardon, Hendrik Treede

1:48_PM Case Presentation: 75-Year-Old With Severe AS And Proximal LAD Stenosis - TAVI Alone, TAVI Plus PCI or SAVR Plus CABG?

Case Presenter: Yousif Ahmad

1:52_PM What the Guidelines Say Virtual Lecturer: Davide Capodanno

1:57_PM What the Heart Team Says Discussant: John K. Forrest, Tsuyoshi

Kaneko, Stephen H. Little, Michael J. Reardon

2:03_PM Case Outcome Case Presenter: Yousif Ahmad

70-Year-Old With Severe Symptomatic Primary MR and Intermediate Surgical Risk Virtual Moderators: Bernard Prendergast Discussants: Anita W. Asgar, Tsuyoshi Kaneko, Azeem Latib Virtual Discussants: Jeroen J. Bax

2:05_PM Case Presentation: 70-Year-Old With Severe Symptomatic Primary MR and Intermediate Surgical Risk

Case Presenter: Aakriti Gupta

2:09_PM What the Guidelines Say Virtual Lecturer: Victoria Delgado

2:14_PM What the Heart Team Says Discussants: Anita W. Asgar, Tsuyoshi

Kaneko, Azeem LatibVirtual Discussants: Jeroen J. Bax

2:20_PM Case Outcome Case Presenter: Aakriti Gupta

79-Year-Old Woman With Mechanical MVR, Severe TR and Early RV Dysfunction. Virtual Moderators: Patrick T. O'Gara Discussants: Anita W. Asgar, Tsuyoshi Kaneko, Azeem Latib Virtual Discussants: Jeroen J. Bax

2:22_PM Case Presentation: 79-Year-Old Woman With Mechanical MVR, Severe TR and Early RV Dysfunction

Case Presenter: Tom Cahill

2:26_PM What the Guidelines Say Virtual Lecturer: Stephan Baldus

2:31_PM What the Heart Team Says Discussants: Anita W. Asgar, Tsuyoshi

Kaneko, Azeem LatibVirtual Discussants: Jeroen J. Bax

2:37_PM Case Outcome Case Presenter: Tom Cahill

2:39_PM Summary and Take Home Messages Intro/ Closing Presenter: Patrick T. O'Gara

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Structural Heart Disease #3 - Mount Sinai Medical Center, New York City, NY - LAAO

Live Cases Structural: Non-Valve _

Live Case Theater





2:45 PM - 3:40 PM

Structural Heart Disease #3 - Mount Sinai Medical Center, New York City, NY - LAAO Live Case Moderators: Mohamad Alkhouli Live Case Co-Moderators: Brijeshwar Maini Live Case Discussants: Maurice Buchbinder, Omar K. Khalique, Carlos E. Sanchez Virtual Live Case Discussants: Reda Ibrahim Live Case Operators: Srinivas R. Dukkipati, Vivek Y. Reddy

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Structural Heart Disease #4 - Columbia University Medical Center, New York City, NY

Live Cases Structural: Non-Valve _

Live Case Theater



3:45 PM - 4:40 PM

Structural Heart Disease #4 - Columbia University Medical Center, New York City, NY Live Case Moderators: Jacqueline Saw Live Case Co-Moderators: Saibal Kar Live Case Discussants: Megan Coylewright, Brijeshwar Maini, Ramon Quesada Virtual Live Case Discussants: Horst Sievert Live Case Operators: Rebecca T. Hahn, Nadira Hamid, Vivian G. Ng, Robert J. Sommer, Torsten P. Vahl

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Live Case Theater



4:45 PM - 5:40 PM


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Structural Heart Disease #5 - Erasmus University-Thoraxcenter, Rotterdam, the Netherlands

Live Cases Structural: Non-Valve Structural: Valve _

Live Case Theater



5:45 PM - 6:45 PM

Structural Heart Disease #5 - Erasmus University-Thoraxcenter, Rotterdam, the Netherlands Live Case Moderators: Azeem Latib Live Case Co-Moderators: Michael J. Reardon Live Case Discussants: Michael A. Borger, Katherine B. Harrington, Ganesh Manoharan, Giuseppe Tarantini Live Case Operators: Joost Daemen, Wijnand Den Dekker, Roberto Diletti, Nicolas M. Van Mieghem, Jeroen M. Wilschut

5:45_PM Live Case Introduction for Structural Heart Disease #5 - Erasmus University-Thoraxcenter, Rotterdam, the Netherlands

Moderator: Martin B. Leon 5:50_PM Structural Heart Disease #5 - Erasmus University-Thoraxcenter,

Rotterdam, the Netherlands _

Satellite: Clinical Science to Landmark Trials of LV Unloading in HR-PCI and CS

Satellites _

Clinical Science Theater



6:30 AM - 7:30 AM

Clinical Science to Landmark Trials of LV Unloading in HR-PCI and CS

6:30_AM PROTECT Series leading to PROTECT IV Satellite Presenter: Gregg W. Stone

6:45_AM Real World Evidence leading to RECOVER IV Satellite Presenter: William W. O'Neill

7:00_AM Door to Unload: Implications for STEMI, HR-PCI and Cardiogenic Shock



Virtual Satellite Presenter: Navin K. Kapur 7:10_AM Breaking the Small-Bore Barrier

Satellite Presenter: Amir Kaki 7:25_AM Q&A/Panel Discussion

Discussants: Daniel Burkhoff, Amir Kaki, William W. O'Neill, Gregg W. StoneVirtual Discussants: Navin K. Kapur

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Coronary Hot Topic #1: Revascularization Decisions in Chronic Coronary Syndromes, Part 1

Coronary: Core _




8:00 AM - 8:45 AM

Coronary Hot Topic #1: Revascularization Decisions in Chronic Coronary Syndromes, Part 1 Moderators: Sripal Bangalore Virtual Moderators: Rasha Al-Lamee Discussants: Suzanne J. Baron Virtual Discussants: Jagat Narula, Giulio G. Stefanini

8:00_AM Introduction Intro/ Closing Presenter: Rasha Al-Lamee, Sripal Bangalore

8:02_AM The ISCHEMIA Sub-studies: Highlights and Take-Home Messages Virtual Lecturer: David J. Maron

8:09_AM Roundtable Discussion Guest Discussant: David J. Maron

8:17_AM Quality of Life Matters to Patients: How ISCHEMIA and ORBITA Have Informed Our Practice

Lecturer: Suzanne V. Arnold 8:23_AM Roundtable Discussion

Discussant: Suzanne V. Arnold 8:31_AM What’s Next for Chronic Coronary Syndromes? Upcoming Clinical

Trials Virtual Lecturer: Christopher Rajkumar

8:37_AM Roundtable Discussion and Wrap-up Guest Discussant: Christopher Rajkumar

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Coronary Hot Topic #1: Revascularization Decisions in Chronic Coronary Syndromes, Part 2

Coronary: Core _




8:45 AM - 9:30 AM

Coronary Hot Topic #1: Revascularization Decisions in Chronic Coronary Syndromes, Part 2 Moderators: Dipti Itchhaporia, Gregg W. Stone Discussants: David J. Cohen, Margaret B. McEntegart Virtual Discussants: Pamela S. Douglas

8:45_AM Introduction Intro/ Closing Presenter: Dipti Itchhaporia, Gregg W. Stone

8:46_AM Debate 1: Pro – Functional Testing Matters; We Need to Follow the ACC/AHA Guidelines

Virtual Lecturer: Raymond Y. Kwong 8:52_AM Debate 1: Con – Anatomy First; NICE Guidelines Got It Right

Virtual Lecturer: Nick Curzen 8:58_AM Debate 1: Discussion 9:07_AM Debate 2: Pro – The ISCHEMIA Trial Results Do Not Apply to CABG;

Our Outcomes Are Different! Virtual Lecturer: Mario FL Gaudino

9:13_AM Debate 2: Con – The ISCHEMIA Results Apply to All Revascularization; We All Need to Reconsider Our Approach

Lecturer: Sripal Bangalore 9:19_AM Debate 2: Discussion & Wrap-up

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Structural Hot Topic #1: Two Deep Dives – Bicuspids and Bioprosthetic Valve Failure, Part 1

Structural: Valve _




9:30 AM - 10:15 AM

Session I: TAVR in Bioprosthetic Valve Failure Moderators: Keith B. Allen, Ran Kornowski Discussants: Vinayak N. Bapat, Tsuyoshi Kaneko Virtual Discussants: Danny Dvir

9:30_AM Bioprosthetic Valve Failure: Redo SAVR or ViV TAVR? Lecturer: Kendra J. Grubb

9:37_AM Roundtable Discussion Guest Discussant: Kendra J. Grubb

9:41_AM Mitigating Coronary Obstruction: Snorkel or Slice Virtual Lecturer: Jaffar M. Khan

9:48_AM Roundtable Discussion Guest Discussant: Jaffar M. Khan

9:52_AM Bioprosthetic Valve Fracture: All or Some, When, and How? Lecturer: Adnan K. Chhatriwalla

9:59_AM Roundtable Discussion



Guest Discussant: Adnan K. Chhatriwalla 10:03_AM TAV in TAV: The First TAVR Matters

Virtual Lecturer: Janarthanan Sathananthan 10:10_AM Roundtable Discussion and Wrap-up

Guest Discussant: Janarthanan Sathananthan _

Structural Hot Topic #1: Two Deep Dives – Bicuspids and Bioprosthetic Valve Failure, Part 2

Structural: Valve _




10:15 AM - 11:00 AM

Session II. TAVR in Bicuspid Aortic Valve Disease Moderators: John K. Forrest Virtual Moderators: Thomas Modine Discussants: Alexandra J. Lansky, Tamim M. Nazif, Rishi Puri, Basel Ramlawi

10:15_AM Introduction and Session Objectives Intro/ Closing Presenter: John K. Forrest

10:16_AM Lessons From the CTA: For Bicuspid It’s About Calcium Not About Sievers

Lecturer: Raj Makkar 10:21_AM Implant Strategies for Optimizing Procedural Outcomes in Bicuspid

TAVR Virtual Lecturer: Didier Tchetche

10:26_AM Review of Bicuspid TAVR Data in Intermediate and High-Risk Patients

Lecturer: Hasan Jilaihawi 10:31_AM Roundtable Discussion 10:38_AM TAVR in Bicuspid Low-Risk Patients Flaming Hot Debate: A Low-Risk

Randomized Trial in Bicuspid AS Is Needed! 10:38_AM Con: Absolutely Not – A Waste of Time and

Money Lecturer: Lindsey Prescher

10:44_AM Pro: Emphatically YES – And Here Is the Design

Virtual Lecturer: Vinod H. Thourani

10:50_AM Roundtable Discussion 10:58_AM Final Thoughts and Next Steps in Bicuspid TAVR

Intro/ Closing Presenter: John K. Forrest _

Late-Breaking Clinical Trials Session I, In Collaboration With Lancet

Late Breaking Science _


THURSDAY, NOVEMBER 04, 2021 11:00 AM - 12:00 PM


11:00 AM - 12:00 PM

Late-Breaking Clinical Trials Session I, In Collaboration With Lancet Co-Moderators: Gregg W. Stone Virtual Moderators: Stuart Spencer Discussants: Nils Johnson, Marc Etienne Jolicoeur, Ran Kornowski Virtual Discussants: Bernard De Bruyne, Mario FL Gaudino, Marie-Claude Morice, Gennaro Sardella

11:00_AM FAME 3: A Randomized Trial of FFR-Guided Stenting Compared With CABG

Presenter: William F. Fearon 11:12_AM Discussion

Guest Discussant: William F. Fearon 11:20_AM FAVOR III China: A Sham-Controlled Randomized Trial Comparing

QFR-Guided and Angiography-Guided PCI Virtual Presenter: Bo Xu

11:32_AM Discussion Guest Discussant: Bo Xu

11:40_AM SUGAR: A Randomized Trial of Amphilimus-eluting Stents and Zotarolimus-eluting Stents in Patients With Diabetes

Virtual Presenter: Rafael Romaguera 11:52_AM Discussion

Guest Discussant: Rafael Romaguera _

Late-Breaking Clinical Science Session I, In Collaboration With Circulation





1:00 PM - 2:00 PM

Late-Breaking Clinical Science Session I, In Collaboration With Circulation Moderators: Sunil V. Rao Co-Moderators: Joseph A. Hill Discussants: Ioanna Kosmidou, Dharam J. Kumbhani, Jennifer Rymer Virtual Discussants: Felix Mahfoud, Mamas Mamas, Lorenz Raber, Patrick W. Serruys



1:00_PM OPTIMUM: Early Outcomes From a Prospective Registry of PCI in Patients at Prohibitive Risk for CABG

Presenter: David E. Kandzari 1:10_PM Discussion

Guest Discussant: David E. Kandzari 1:15_PM EROSION III: A Randomized Trial of OCT-Guided Intervention in STEMI

Patients With Early Infarct Artery Patency Virtual Presenter: Haibo Jia

1:25_PM Discussion Guest Discussant: Haibo Jia

1:30_PM RADIANCE-HTN: Six-Month Outcomes of a Randomized Trial of Renal Denervation Versus a Sham Procedure for Resistant Hypertension – Impact of Treatment-Blinded Medication Titration

Virtual Presenter: Ajay J. Kirtane 1:40_PM Discussion

Guest Discussant: Ajay J. Kirtane 1:45_PM iFR-SWEDEHEART: Five-Year Outcomes of a Randomized Trial of iFR-

Guided vs. FFR-Guided PCI Virtual Presenter: Matthias Götberg

1:55_PM Discussion Guest Discussant: Matthias Götberg

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Special Hot Topic Session: COVID Vaccine Update




2:00 PM - 2:20 PM

Special Hot Topic Session: COVID Vaccine Updates Moderators: Ran Kornowski, Roxana Mehran Discussants: Guy Witberg Virtual Discussants: Robert M. Califf, Elazer R. Edelman, James B. Hermiller Jr, Farouc A. Jaffer

2:00_PM Myocarditis After Covid-19 Vaccination: What Clinicians Need to Know

Lecturer: Guy Witberg 2:08_PM Roundtable Discussion

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Coronary Hot Topic #2 & #3: LM and Bifurcation Essentials – From Evidence to Experience

Coronary: Core _




2:20 PM - 4:00 PM

Left Main and Bifurcation Summit Moderators: Antonio Colombo, David E. Kandzari Virtual Discussants: Alaide Chieffo, Cindy L. Grines, David Hildick-Smith, Kathleen Kearney

2:20_PM The Most Relevant Studies Regarding Bifurcation Lesions in the Past Two Years

Lecturer: Nadia R. Sutton 2:28_PM Should We Have a Different Approach for Left Main Bifurcation

Lesions vs Non-Left Main Bifurcation Lesions? Virtual Lecturer: Shao-Liang Chen

2:35_PM Why the Ostial Circumflex Has More Restenosis and How to Prevent It

Virtual Lecturer: Vladimir Dzavik 2:42_PM Top Tips and Tricks for Bifurcation: My Top Five

Virtual Lecturer: Thierry Lefevre 2:50_PM Roundtable Discussion 3:00_PM Cases Supporting Provisional and Planned Two-Stent Methods

3:00_PM Case 1: Provisional With One Stent – Does FFR Help Us?

Virtual Case Presenter: Bon-Kwon Koo

3:08_PM Case 2: Provisional Ending With Two Stents Lecturer: Katherine Kunkel

3:16_PM Case 3: Planned Two Stents and Why I Chose This Two-Stent Technique

Virtual Case Presenter: Sahil Khera

3:24_PM Roundtable Discussion 3:34_PM My Personal Approach to Bifurcation Lesions in 2021

Lecturer: Antonio Colombo 3:42_PM The Role of Drug Coated Balloons in Bifurcation Lesions

Virtual Lecturer: Robert A. Byrne 3:50_PM Roundtable Discussion & Wrap-Up: Top Ten Things About

Bifurcations You Should Know but the Trials Don’t Tell You _

Structural Hot Topic #3: Two Deep Dives – Tricuspid Leaflet Grasping and Replacement Therapies, Part 1

Structural: Valve _






4:00 PM - 4:45 PM

Session I: Transcatheter Tricuspid Leaflet Grasping Therapies Moderators: Charles J. Davidson, Molly Szerlip Discussants: Edwin Ho Virtual Discussants: Mackram F. Eleid, Jörg Hausleiter, Pradeep K. Yadav

4:00_PM Standardized Nomenclature for Leaflet Anatomy and Utility for Pre-procedural TEER Planning

Virtual Lecturer: Philipp Lurz 4:05_PM Imaging Optimization and Algorithm for Procedural Success

Lecturer: Scott M. Chadderdon 4:10_PM Triluminate Registry: Lessons Learned for TEER Trial Design

Lecturer: Georg Nickenig 4:15_PM Pascal EFS, EU Registry, and Compassionate Use Outcomes

Lecturer: Charles J. Davidson 4:20_PM Who Is the Ideal Candidate for TEER? Clinical and Anatomical

Considerations Lecturer: Jason H. Rogers

4:25_PM Case Presentations 4:25_PM Triluminate

Case Presenter: Paul Sorajja

4:28_PM CLASP Case Presenter: Molly Szerlip

4:31_PM Roundtable Discussion and Wrap-Up _

Structural Hot Topic #3: Two Deep Dives – Tricuspid Leaflet Grasping and Replacement Therapies, Part 2

Structural: Valve _




4:45 PM - 5:30 PM

Session II. Transcatheter Tricuspid Valve Replacement Moderators: Azeem Latib, Raj Makkar Discussants: Stanley J. Chetcuti, Jennifer Cowger, Molly Szerlip Virtual Discussants: Gorav Ailawadi

4:45_PM Transcatheter Tricuspid Valve Replacement: Overview of Current Clinical State

Lecturer: Molly Szerlip 4:52_PM Keys to Procedural Success

4:52_PM Understanding the IVC to Tricuspid Annulus Anatomic Relationship

Virtual Lecturer: Torsten P. Vahl

4:57_PM Don't Trip on the Wires: Managing Pacemaker Leads During TTVR

Virtual Lecturer: Neil P. Fam

5:02_PM Identification and Management of Patients at High Risk for Conduction Abnormalities

Lecturer: Azeem Latib

5:07_PM Roundtable Discussion

5:12_PM Decision-Making Hot Topics 5:12_PM The Slippery Slope of "Too Much RV

Dysfunction for TTVR" (Lessons From Surgery)

Virtual Lecturer: Paul A. Grayburn

5:18_PM The Role of Heart Failure Optimization Pre- and Post-Procedure

Virtual Lecturer: Sean P. Pinney

5:24_PM Roundtable Discussion and Wrap-Up: Repair or Replacement _

Coronary Hot Topic #4: The Challenges of Complex Lesions – A Case-Based Problem-Oriented Symposium, Part 1, Supported through Unrestricted Educational Grants from Medtronic and Boston Scientific Corporation

Coronary: Core _




5:30 PM - 6:15 PM

Session 1: Have We Conquered Calcium? Moderators: Kevin Bainey, Margaret B. McEntegart Discussants: Kevin J. Croce, Sanjog Kalra Virtual Discussants: Perwaiz M. Meraj

5:30_PM Introduction Intro/ Closing Presenter: Kevin Bainey, Margaret B. McEntegart

5:32_PM Case Presentation: Challenging Calcified CAD Case Presenter: Katherine Kunkel

5:35_PM Rotational Atherectomy First, Ask Questions Later! Lecturer: Rhian E. Davies

5:41_PM Orbital Atherectomy: One Burr Fits All! Lecturer: Evan Shlofmitz

5:47_PM IVL: Be Modern! Lecturer: Stefan Harb

5:53_PM Balloons Do the Trick: Save the Bucks! Virtual Lecturer: Megha Prasad



5:59_PM Roundtable Discussion: How I Would Treat This Case? 6:10_PM Case Outcome: Challenging Calcified CAD

Case Presenter: Katherine Kunkel 6:13_PM Closing Thoughts & Adjourn

Intro/ Closing Presenter: Kevin Bainey, Margaret B. McEntegart _

Coronary Hot Topic #4: The Challenges of Complex Lesions – A Case-Based Problem-Oriented Symposium, Part 2, Supported through Unrestricted Educational Grants From Medtronic and Boston Scientific Corporation

Coronary: Core _




6:15 PM - 7:00 PM

Session 2: Unresolved Issues in Complex Coronary PCI Moderators: Darshan Doshi Virtual Moderators: Jean Fajadet Discussants: Allen Jeremias Virtual Discussants: Mitul P. Patel, Megha Prasad, Robert Francis Riley

6:15_PM Debate: How Do We Know PCI Is Successful? Imaging Endpoints Make the Most Sense

Lecturer: Natalia Pinilla-Echeverri 6:20_PM Debate: How Do We Know PCI Is Successful? Physiology Will

Rule Lecturer: Allen Jeremias

6:25_PM Debate Discussion: How Do We Know PCI Is Successful? 6:29_PM Case Presentation: My Burr Is Stuck, Now What?

Virtual Case Presenter: Kathryn Dawson 6:33_PM Roundtable Discussion 6:39_PM Case Conclusion and Tips: My Burr Is Stuck, Now What?

Virtual Case Presenter: Kathryn Dawson 6:44_PM Case Presentation: And There Was No Reflow…

Case Presenter: Jeremy D. Rier 6:48_PM Roundtable Discussion 6:54_PM Case Conclusion and Tips: And There Was No Reflow…

Case Presenter: Jeremy D. Rier 6:59_PM Closing Thoughts & Adjourn

Intro/ Closing Presenter: Jean Fajadet _

Satellite: Coronary DCB: The European Standard and Still Not in the U.S. Toolbox? Why, When and How?

Satellites _

Innovation Theater



6:30 AM - 7:30 AM

Coronary DCB: The European Standard and Still Not in the U.S. Toolbox? Why, When and How?

6:30_AM Non-Stent Based Local Drug Delivery: Importance in Interventional Cardiology Today

Satellite Presenter: Juan F. Granada 6:42_AM Where are we now? Current Global Acceptance of Coronary DCB as a

Standard of Care vs. DES Satellite Presenter: Bruno Scheller

6:52_AM Real-World Examples of Drug-Coated Balloon Integration into Interventional Procedures

Virtual Satellite Presenter: rosli mohd ali 7:02_AM Recognizing the Value Proposition of DCB in the Real-World

Satellite Presenter: David J. Cohen 7:12_AM Discussion

Moderators: Alexandra J. Lansky, Jorge F. SaucedoDiscussants: David J. Cohen, Juan F. Granada, Bruno SchellerVirtual Discussants: rosli mohd ali

_

Featured Clinical Research Session I

Innovation Theater



8:00 AM - 9:00 AM

Featured Research Clinical Research Session I Co-Moderators: Gary S. Mintz Virtual Moderators: Anthony DeMaria Discussants: Mauricio G. Cohen, Ariel Finkelstein, Hector M. Garcia-Garcia, Shigeru Saito Virtual Discussants: Philipp Blanke, Jennifer A. Tremmel, Carlos E. Uribe

8:00_AM Canadian SCAD: Long-Term Clinical Outcomes of SCAD From the Nationwide Prospective North American Registry

Presenter: Jacqueline Saw 8:08_AM Discussion

Guest Discussant: Jacqueline Saw 8:12_AM SR-SCAD: Long-Term Clinical Outcomes of SCAD From the Nationwide

Prospective Spanish Registry Virtual Presenter: Marcos Garcia-Guimaraes

8:20_AM Discussion Guest Discussant: Marcos Garcia-Guimaraes

8:24_AM Outcomes of Repeat TAVR With Balloon-Expandable Sapien 3/Ultra Valves



Presenter: Raj Makkar 8:32_AM Discussion

Guest Discussant: Raj Makkar 8:36_AM Outcomes of Repeat TAVR According to the Initial and Subsequent

TAVR Type Presenter: Uri Landes

8:44_AM Discussion Guest Discussant: Uri Landes

8:48_AM HALT: Long-Term Clinical Impact of Hypoattenuating Leaflet Thickening After TAVR

Virtual Presenter: Santiago Garcia 8:56_AM Discussion

Guest Discussant: Santiago Garcia _

Structural Hot Topic #2: Expanding Vision of Transcatheter Tricuspid Valve Therapies

Structural: Valve _

Innovation Theater



9:00 AM - 10:00 AM

Expanding Vision of Transcatheter Tricuspid Valve Therapies Moderators: Francesco Maisano Virtual Moderators: Jörg Hausleiter Discussants: Laura Davidson Virtual Discussants: Mackram F. Eleid, Josep Rodés-Cabau

9:00_AM Risk Scores for Tricuspid Valve Intervention: Defining Cohort C Virtual Lecturer: Gorav Ailawadi

9:06_AM Imaging for Transcatheter Tricuspid Valve Interventions: Is This the Limiting Factor?

Virtual Lecturer: Rebecca T. Hahn 9:11_AM Roundtable Discussion 9:20_AM Flash Debate

9:20_AM Transcatheter Repair Devices Will Be the Dominant Solution

Virtual Lecturer: Jörg Hausleiter

9:25_AM Transcatheter Replacement Devices Will Be the Dominant Solution

Lecturer: Firas Zahr

9:30_AM Roundtable Discussion 9:40_AM Controversies Surrounding Transcatheter Devices: Durability,

Anticoagulation, Conduction, and More Virtual Lecturer: Josep Rodés-Cabau

9:45_AM Novel Transcatheter Tricuspid Valve Devices: A Lens Into the Future Lecturer: Azeem Latib

9:50_AM Roundtable Discussion and Wrap-up _

TCT Shark Tank

Innovation & FDA Townhall _

Innovation Theater



10:00 AM - 12:00 PM

TCT Innovation: Shark Tank

10:00_AM Interventional Innovation in the Post-COVID 19 Era: Lessons Learned and the Future Path Forward

Moderators: Peter J J. Fitzgerald, Martin B. LeonDiscussants: Andrew Cleeland, Ian T. Meredith, Stanton J. Rowe

10:20_AM TCT Shark Tank Innovation Competition Moderators: Louis A. Cannon, Andrew CleelandDiscussants: Rafael

Beyar, Daniel Burkhoff, Peter J J. Fitzgerald, Robert S. Schwartz 10:20_AM Introduction to TCT2021 Innovation

Competition Lecturer: Juan F. Granada

10:25_AM LungPacer: Diaphragm Pacing Therapy System for Mechanically Ventilated Patients

Moderators: James S. Eadie Lecturers: Doug Evans

10:33_AM Q&A

10:41_AM MMI Symani: Microrobotic Surgical System Moderators: Rafael Beyar

Lecturers: Mark Toland

10:49_AM Q&A

10:57_AM Medyria PhysioCath: A Step Ahead in Coronary Physiology Assessment (TCT42939)

Moderators: Allen Jeremias Lecturers: Mauro Massimo Sette

11:05_AM Q&A

11:13_AM ViewMind: Neurocognitive Digital Biomarkers Powered by AI

Moderators: Peter J J. Fitzgerald Lecturers: Mark Edwards

11:21_AM Q&A

11:29_AM Amplitude Vascular: Novel Approach to Intravascular Lithotripsy

Moderators: J. Aaron Grantham Lecturers: Hitinder Gurm



11:37_AM Q&A

11:45_AM Aquapass: Non-Invasive Treatment for Fluid Overload in Chronic Heart Failure Patients

Moderators: William T. Abraham Lecturers: Yaacov Nitzan

11:53_AM Q&A

_

FDA Town Hall Session I: Impact of COVID-19


Innovation Theater



1:00 PM - 1:30 PM

Impact of COVID-19 Moderators: Roxana Mehran Virtual Moderators: Bram D. Zuckerman Discussants: Donald Cutlip, Aaron V. Kaplan, Ian T. Meredith Virtual Discussants: Robert M. Califf, Mitchell W. Krucoff, Laura Mauri

1:00_PM Impact of the COVID-19 Pandemic on FDA: Review of Changes and Looking Ahead

Virtual Lecturer: William H. Maisel 1:10_PM Panel Discussion

Guest Discussant: William H. Maisel _

FDA Town Hall Session II: Responding to a Black Swan Event


Innovation Theater



1:30 PM - 2:00 PM

Responding to a Black Swan Event Moderators: Gregg W. Stone Virtual Moderators: Andrew Farb Discussants: Jodi J. Akin, Ori Ben-Yehuda, Sandeep Brar, JoAnn Lindenfeld Virtual Discussants: Deepak L. Bhatt, Heng Li, Janet Wittes

1:30_PM Adapting Clinical Trials to a Black Swan Event, from the FDA Perspective

Virtual Lecturer: Andrew Farb 1:35_PM Adapting Clinical Trials to a Black Swan Event, from Industry

Perspective Lecturer: Sandeep Brar

1:40_PM Panel Discussion _

FDA Town Hall Session III: Pragmatic Clinical Trials


Innovation Theater



2:00 PM - 2:30 PM

Pragmatic Clinical Trials Moderators: Martin B. Leon Virtual Moderators: Nicole Ibrahim Discussants: Michael J. Mack Virtual Discussants: Annetine C. Gelijns, Norman L. Stockbridge, Alec S. Vahanian, Changfu Wu

2:00_PM Pragmatic Clinical Trials: The Future is Now? Virtual Lecturer: Sreekanth Vemulapalli

2:10_PM Panel Discussion Guest Discussant: Sreekanth Vemulapalli

_

Emerging Technological Trends I: Transcatheter Mitral & Tricuspid Technologies - Part I

Innovation _

Innovation Theater



2:30 PM - 3:30 PM

Emerging Technological Trends I Transcatheter Mitral & Tricuspid Technologies Moderators: Raj Makkar Virtual Moderators: Thomas Modine Discussants: Oscar A. Mendiz, Michael Joseph Rinaldi, Toby Rogers Virtual Discussants: Tariq Ahmad, Nicolo Piazza, Julia Seeger

2:30_PM A Glimpse into the Future of Catheter Based-Mitral Intervention



2:30_PM Sapien M3 Trans-Septal TMVR: Case Presentation and Clinical Program Description

Lecturer: Raj Makkar

2:42_PM Featured Lecture: Air Embolism During Large Bore Cardiovascular Procedures- The Big Elephant in the Room

Lecturer: Tilo Kölbel


2:55_PM Innovation in Mitral Valve Repair Technologies 2:55_PM Transseptal Transcatheter Mitral Valve

Chordal Repair Using the CardioMech Valve Repair System: Early First in Human Experience

Lecturer: Michael Joseph Rinaldi

3:02_PM Transfemoral Multi-segment Chordal Replacement and Annuloplasty in a Single Device for Degenerative MR (Vesalius Cardiovascular)

Lecturer: Peter Skarsgard

3:09_PM Ventricular Reshaping Technologies 3:09_PM V-Sling: Transcatheter Ventricular Repair

Devices for Heart Failure Patients (Cardiac Success)

Lecturer: Gregg W. Stone

3:16_PM Transcatheter Mitral Cerclage Annuloplasty for Functional Mitral Regurgitation: Technology Review and Case Presentations

Lecturer: Toby Rogers


_

Emerging Technological Trends I: Transcatheter Mitral & Tricuspid Technologies - Part 2

Innovation _

Innovation Theater



3:30 PM - 4:00 PM

Innovation in Transcatheter Tricuspid Valve Replacement Technologies Virtual Moderators: Eberhard Grube, Thomas Modine Discussants: Philippe Genereux, Leonardo Paim, Jonathan G. Schwartz

3:30_PM Tricuspid Valve Replacement With a Novel Transcatheter Heart Valve Replacement System: Early Human Clinical Experience (TRiCares)

Lecturer: Hendrik Treede 3:37_PM Safety and Efficacy of the TricValve® Transcatheter Bicaval Valves

System in the Superior and Inferior Vena Cava in Patients with Severe Tricuspid Regurgitation

Virtual Lecturer: Rodrigo D. Estevez-Loureiro 3:44_PM Temporary Implantation of the CroiValve DUO Coaptation Valve in

Patients with Massive and Torrential Tricuspid Regurgitation Virtual Lecturer: Stephen A. O'Connor

3:51_PM Roundtable Discussion _

What’s Novel in Interventional Hypertension

Innovation Theater



4:00 PM - 6:00 PM

What’s Novel in Interventional Hypertension

4:00_PM Session I: Hypertension Management and Challenges in 2021 Moderators: Michael JonasVirtual Moderators: Eric A.

SecemskyDiscussants: Jay S. GiriVirtual Discussants: Natalie A. Bello, Debbie Cohen, MD, Naomi Fisher

4:00_PM Dietary and Pharmacologic Approaches to Hypertension Management in 2021 – What’s New and What’s Changed

Virtual Lecturer: Debbie Cohen, MD

4:10_PM Patient Preferences for Interventional versus Pharmaceutical Treatments Among U.S. Adults with Uncontrolled Hypertension

Lecturer: Michael A. Weber


4:23_PM Session II: Device-Based Hypertension Trial Update — What’s New, What’s Relevant, What’s Next, Supported through an Unrestricted Educational Grant from ReCor Medical

Moderators: Florian RaderVirtual Moderators: Joost DaemenVirtual Discussants: Keith C. Ferdinand, Philipp Lurz, Andrew Sharp

4:23_PM Preclinical Studies of Renal Denervation and Application to Clinical Trials and Practice

Virtual Lecturer: Aloke Finn

4:31_PM Update on RADIANCE Trials Program (Ultra-Sound Renal Denervation): Clinical Trials Status Update

Virtual Lecturer: Ajay J. Kirtane



4:41_PM TARGET BP Trials Program (Chemical Renal Denervation): Clinical Trials Status Update

Virtual Lecturer: Felix Mahfoud

4:49_PM The SPYRAL Clinical Trials Program (Radiofrequency Renal Denervation): Clinical Trials Status Update

Lecturer: David E. Kandzari

4:59_PM Roundtable Disucssion

5:09_PM Pacemaker-Mediated Baroreflex Stimulation: New Clinical Data and Further Follow-up

Lecturer: Daniel Burkhoff

5:17_PM Next Steps for Clinical Studies of Interventional Hypertensive Therapies

Virtual Lecturer: Naomi Fisher


5:30_PM Session III: Interventional Hypertension in the Clinic Virtual Moderators: Joost Daemen, Felix MahfoudDiscussants: Jay S.

Giri, David E. KandzariVirtual Discussants: Chandan Devireddy, Payal Kohli

5:30_PM Debate: My Patient has a Blood Pressure of 150/90 Despite 2 Maximally Dosed Medications – Time for Interventional Therapy!

Virtual Lecturer: Michel Azizi

5:37_PM Debate: My Patient has a Blood Pressure of 150/90 Despite 2 Maximally Dosed Medications – Time for a Third Medication!

Virtual Lecturer: Herbert D. Aronow

5:44_PM Best Practices for the Future Implementation of Interventional Therapies for Hypertension

Virtual Lecturer: Michael Bloch


_

Best of Abstracts

Innovation Theater



6:00 PM - 7:00 PM

Best of Abstracts Moderators: Steven R. Bailey, Jolanta M. Siller-Matula Virtual Discussants: Sonya Burgess, Christine Jee-Young Chung, Joachim Schofer

6:00_PM Changes in Left Ventricular Global Longitudinal Strain in Patients With Heart Failure and Secondary Mitral Regurgitation: The COAPT Trial

Virtual Presenter: Stephan Milhorini Pio

6:07_PM Discussion Guest Discussant: Stephan Milhorini Pio

6:12_PM Cardiac Neuromodulation Therapy reduces Systolic Blood Pressure and Pulse Pressure in Patients With Isolated Systolic Hypertension in a Randomized Double-Blind Study

Presenter: Daniel Burkhoff 6:19_PM Discussion

Discussant: Daniel Burkhoff 6:24_PM Prognosis and Medical Cost of Measuring Fractional Flow Reserve in

Percutaneous Coronary Intervention Virtual Presenter: David Hong

6:31_PM Discussion Guest Discussant: David Hong

6:36_PM Adequacy of Blood Pressure Control in High-Risk Hypertensive Patients: The DEGREE Study

Virtual Presenter: Victor Zeijen 6:43_PM Discussion

Guest Discussant: Victor Zeijen 6:48_PM Buffer

_

Satellite: Ability to beat diabetes globally with an innovative DES+DCB platform

Satellites _

World Connect Studio



6:30 AM - 7:30 AM

Ability to beat diabetes globally with an innovative DES+DCB platform

6:30_AM Session Objectives and Opening Remarks Satellite Presenter: Roxana Mehran

6:31_AM Addressing the unmet needs of overlooked diabetic patients: Do we need dedicated DES platform?

Virtual Satellite Presenter: Roxana Mehran 6:39_AM An Innovative DES+DCB platform to treat diabetics: The Envisolution

Technology Moderators: Roxana MehranVirtual Satellite Presenters: Alexandre

Abizaid 6:46_AM Discussion

Moderators: Roxana MehranDiscussants: Antonio ColomboVirtual Discussants: Alexandre Abizaid, Marie-Claude Morice, Luca Testa

6:51_AM Abluminus DES+ : insights and updates on the clinical program Moderators: Roxana MehranVirtual Satellite Presenters: Luca Testa

7:01_AM Ability OCT Study - Imaging Study comparing Abluminus DES vs. Xience Family

Moderators: Roxana MehranVirtual Satellite Presenters: Antonio Colombo



7:11_AM Time to go Global – largest RCT to treat diabetics: ABILITY DIABETES GLOBAL

Moderators: Roxana MehranVirtual Satellite Presenters: Marie-Claude Morice

7:21_AM Discussion & Conclusion Moderators: Roxana MehranDiscussants: Antonio ColomboVirtual

Discussants: Alexandre Abizaid, Marie-Claude Morice, Luca Testa _

Satellite: Optimizing Outcomes in Calcific Cardiovascular Disease: Real-World Techniques with the Diamondback 360® Orbital Atherectomy System

Satellites _




10:00 AM - 11:00 AM

Optimizing Outcomes in Calcific Cardiovascular Disease: Real-World Techniques with the Diamondback 360® Orbital Atherectomy System

10:00_AM Welcome and Case Introduction Discussants: Emmanouil S. Brilakis, Kevin J. Croce, Ki ParkVirtual

Discussants: Michael Kim, Nicolas M. Van MieghemSatellite Presenters: Jasvindar Singh

10:05_AM Case Preparation, Accessing the Lesion and the Use of Imaging to Inform Treatment

Discussants: Emmanouil S. Brilakis, Kevin J. Croce, Ki ParkVirtual Discussants: Michael Kim, Nicolas M. Van MieghemSatellite Presenters: Jasvindar Singh

10:30_AM Orbital Atherectomy Best Practices for Challenging Lesions Discussants: Emmanouil S. Brilakis, Kevin J. Croce, Ki ParkVirtual


10:55_AM Case Wrap-Up and Takeaways Discussants: Emmanouil S. Brilakis, Kevin J. Croce, Ki ParkVirtual


_

Satellite: Novel Technologies for Interventional Guidance – 4D ICE, Fusion, and Holograms

Satellites _




1:00 PM - 2:00 PM

Novel Technologies for Interventional Guidance – 4D ICE, Fusion, and Holograms

1:00_PM Introduction and Welcome Satellite Presenter: Helene Houle

1:03_PM The Importance of Echocardiography in Structural Heart Interventions

Virtual Satellite Presenter: Praveen Mehrotra 1:17_PM First Experiences with Holographic Therapy Guidance

Virtual Satellite Presenter: Jacob Dutcher 1:30_PM Novel 4D ICE Imaging Using the NUVISION™ Ultrasound Catheter

Virtual Satellite Presenter: Shephal Doshi 1:45_PM ICE for LAAC: from 2D to 4D

Virtual Satellite Presenter: Brett Gidney _

Innovation at TCT World Connect: LAA Occlusion and Cerebral Protection Sponsored by CRF

Innovation _




2:00 PM - 3:00 PM

LAA Occlusion and Cerebral Protection Sponsored by CRF Moderators: Ramon Quesada, Jacqueline Saw Discussants: Jason H. Rogers, Giora Weisz Virtual Discussants: Dariusz Jagielak, Jens Erik Nielsen-Kudsk

2:00_PM Featured Lecture: Clinical Outcomes of LAAO versus NOACS in Atrial Fibrillation in Patients with Prior Ischemic Stroke: Is There Room for Improvement in Clinical Outcomes?

Virtual Lecturer: Jens Erik Nielsen-Kudsk 2:07_PM Emerging LAA Technologies

2:07_PM Next Generation LAA Exclusion System to Reduce Stroke Risk in AF Patients (Append)

Virtual Lecturer: Zachi Berger

2:14_PM Introducing XCLUDE Integrated Solution. World's First Dedicated LAA 3D Sizing Device and Next-Gen LAA Exclusion Device

Virtual Lecturer: Flavio Airoldi

2:21_PM LAA Closure with the Laminar Device: technology and Clinical Update

Lecturer: Jason H. Rogers


2:34_PM Emerging Concepts in Cerebral Protection 2:34_PM Cerebral Protection in TAVR: The

PROTEMBO C Trial Lecturer: Tobias Schmidt



2:41_PM The EMBRACE Transcatheter Embolic Protection Device

Virtual Lecturer: Elvin Kedhi

2:48_PM Captis: Full-Body Embolic Protection Device Virtual Lecturer: Haim Danenberg


_

Satellite: Small Annulus, Big Clinical Benefits?

Satellites _




3:00 PM - 4:00 PM

Small Annulus, Big Clinical Benefits?

3:00_PM The Incidence of Small Annulus Patients Virtual Satellite Presenter: Howard C. Herrmann

3:07_PM Unique Attributes of Small Annulus Patients Virtual Satellite Presenter: Didier Tchetche

3:16_PM Case Presentation Virtual Discussants: Howard C. Herrmann, Roxana Mehran, Didier

TchetcheVirtual Satellite Presenters: Mohamed Abdel-Wahab 3:33_PM Why is it "SMART" to Focus on Women with Valvular Heart Disease?

Virtual Discussants: Mohamed Abdel-Wahab, Howard C. Herrmann, Didier TchetcheVirtual Satellite Presenters: Roxana Mehran

3:49_PM Discussion Virtual Discussant: Mohamed Abdel-Wahab, Howard C. Herrmann,

Roxana Mehran, Didier Tchetche _

Satellite: Ultra-low contrast PCI case studies in high-risk patients: Techniques and tools to optimize outcomes

Satellites _




4:00 PM - 5:00 PM

Ultra-low contrast PCI case studies in high-risk patients: Techniques and tools to optimize outcomes

4:00_PM Introduction to case: Zero contrast PCI in the RCA for an ACS patient with MVD

Moderators: Ziad A. AliSatellite Presenters: Allen Jeremias 4:01_PM Zero contrast PCI in the RCA for an ACS patient with MVD

Moderators: Ziad A. AliVirtual Satellite Presenters: Allen Jeremias 4:26_PM Discussion: Zero contrast PCI in the RCA for an ACS patient with MVD

Moderators: Ziad A. AliDiscussants: Karim Al-Azizi, Allen Jeremias 4:30_PM Introduction to case: Ultra-low contrast PCI in the LAD for a patient

with CKD and LAA occlusion device Moderator: Karim Al-Azizi

4:31_PM Ultra-low contrast PCI in the LAD for a patient with CKD and LAA occlusion device

Virtual Satellite Presenter: Karim Al-Azizi 4:56_PM Discussion: Ultra-low contrast PCI in the LAD for a patient with CKD

and LAA occlusion device Moderators: Karim Al-AziziDiscussants: Ziad A. Ali, Allen Jeremias

THURSDAY, NOVEMBER 04, 2021 - _

Aortic Stenosis, Aortic Insufficiency, and TAVR I

Structural: Valve _

Moderated Posters



8:00 AM - 8:36 AM

Aortic Stenosis, Aortic Insufficiency, and TAVR I Moderators: Itsik Ben-Dor, Brijeshwar Maini Discussants: Mazen Albaghdadi

8:00_AM TCT 41: Treatment and Outcomes of Aortic Stenosis in Elderly Patients in the United States: Temporal Trends and Age Differences

Moderated Poster Presenter: Alexis Kofi Okoh 8:07_AM Discussion 8:12_AM TCT 42: Impact of Right Ventricle-Pulmonary Artery Coupling on

Clinical Outcomes After Transcatheter and Surgical Aortic Valve Replacement: An Analysis of the PARTNER 3 Trial

Moderated Poster Presenter: Tom Cahill 8:19_AM Discussion 8:24_AM TCT 45: Indications and Clinical Outcomes With Surgical Explantation

of Chronically Implanted TAVR Prostheses A Report From the HjärtKIRurgi Registry and SWENTRY TAVR Registry

Moderated Poster Presenter: Amalin Sorajja 8:31_AM Discussion

_

Imaging and Physiology I

Coronary: Core _

Moderated Posters





9:15 AM - 9:51 AM

Imaging and Physiology I Moderators: Morton J. Kern Discussants: M Chadi Alraies, Nils Johnson

9:15_AM TCT 79: Changes in Coronary Lipid Composition During 2-Year Follow-up After Acute Myocardial Infarction: Serial NIRS-IVUS Assessment From The PROSPECT ABSORB Trial

Moderated Poster Presenter: Mitsuaki Matsumura 9:22_AM Discussion 9:27_AM TCT 81: Absolute Zero-Contrast Percutaneous Coronary Intervention

Under Intra Vascular Ultrasound guidance in Chronic Kidney Disease Patients – From Despair to Hope?

Moderated Poster Presenter: Pratap Kumar 9:34_AM Discussion 9:39_AM TCT 82: Thin-Cap Fibroatheroma Rather Than Any Lipid Plaques

Increases the Risk of Cardiovascular Events: Insights From the COMBINE FFR-OCT Trial

Moderated Poster Presenter: Wojciech Wojakowski 9:46_AM Discussion

_

SCAD and Non-Atherosclerotic Causes of MI

Coronary: Core _

Moderated Posters



11:00 AM - 11:41 AM

SCAD and Non-Atherosclerotic Causes of MI Moderators: Tanvir K. Bajwa, Giora Weisz Discussants: Susan M. Joseph, Frederick Welt

11:00_AM TCT 124: Spontaneous Coronary Artery Dissection – Effect of Angiographic Type 1 SCAD on Percutaneous Intervention and Clinical Outcomes

Moderated Poster Presenter: Cameron McAlister 11:07_AM Discussion

11:12_AM TCT 125: Incidence and Outcomes of Cardiogenic Shock Among Women With Spontaneous Coronary Artery Dissection

Moderated Poster Presenter: Mohammed Osman 11:19_AM Discussion 11:24_AM Discussion 11:29_AM TCT 127: Diagnostic Yield of Routine Invasive Coronary Physiology

Assessment in Patients with Ischemia and No Obstructive Coronary Artery Disease

Moderated Poster Presenter: Steffne Kunnirickal 11:36_AM Discussion

_

PCI and PCI Outcomes I

Coronary: Core _

Moderated Posters



12:00 PM - 12:24 PM

PCI and PCI Outcomes I Moderators: Steven R. Bailey Discussants: Somjot S. Brar, David L. Fischman, Stefan Harb

12:00_PM TCT 109: Ten-year All-cause Death After Percutaneous or Surgical Revascularization in Diabetic Patients With Complex Coronary Artery Disease

Moderated Poster Presenter: Patrick W. Serruys 12:07_PM Discussion 12:12_PM TCT 113: Ten Years Survival Benefit and Appropriateness of Surgical

or Percutaneous Revascularization Based On Individual Predicted All-Cause Mortality In Patients With Complex Coronary Artery Disease

Moderated Poster Presenter: Patrick W. Serruys 12:19_PM Discussion

_

CTO Intervention

Coronary: CHIP _

Moderated Posters





1:00 PM - 1:24 PM

CTO Intervention Moderators: Khaldoon F. Alaswad, Nicholas Joseph Lembo Discussants: Stephane Rinfret, R. Michael Wyman

1:00_PM TCT 68: Chronic Total Occlusion (CTO) Percutaneous Coronary Intervention (PCI) for patients with prior CABG: Insights from a Pooled Analysis of Four Multicenter Registries

Moderated Poster Presenter: Evangelia Vemmou 1:07_PM Discussion 1:12_PM TCT 72: Primary Versus Secondary Retrograde Approach in Chronic

Total Occlusion Interventions Moderated Poster Presenter: Spyridon Kostantinis

1:19_PM Discussion _

ACS, STEMI, and Cardiogenic Shock

Coronary: CHIP _

Moderated Posters



2:30 PM - 2:54 PM

ACS, STEMI, and Cardiogenic Shock Moderators: Mauricio G. Cohen, Ricardo Santiago Discussants: Mazen Albaghdadi, Kevin Bainey, David A. Wood

2:30_PM TCT 30: A Comparative Analysis of Patient Characteristics in Cardiogenic Shock Trials: Differences Between Randomized Trials and Real-World Registries

Moderated Poster Presenter: Michael Megaly 2:37_PM Discussion 2:42_PM TCT 31: Frailty Adjusted Risk Score for Outcomes in Type 2

Myocardial Infarction Moderated Poster Presenter: Katerina Jurkoshek


Artificial Intelligence and Deep Learning

Coronary: Core Structural: Valve _

Moderated Posters



3:30 PM - 3:54 PM

Artificial Intelligence and Deep Learning Moderators: Dipti Itchhaporia Discussants: Robert S. Schwartz, Richard S. Stack

3:30_PM TCT 59: Comprehensive Coronary Plaque Assessment Software – OCTOPUS-v2

Moderated Poster Presenter: Juhwan Lee 3:37_PM Discussion 3:42_PM TCT 60: Deep Learning Algorithm Predicts Presence of Angiographic

Coronary Artery Disease in Stable Patients Using Only a Standard 12-lead Electrocardiogram

Moderated Poster Presenter: Utkars Jain 3:49_PM Discussion

_

COVID-19

Coronary: CHIP _

Moderated Posters



4:30 PM - 5:30 PM

COVID-19 Moderators: Timothy D. Henry, Mladen I. Vidovich Discussants: David L. Fischman, Hitinder Gurm

4:30_PM TCT 63: NACMI (North American COVID-19 Myocardial Infarction) Risk Score for Prediction of In-Hospital Mortality

Moderated Poster Presenter: Payam Dehghani 4:37_PM Discussion 4:42_PM TCT 64: Racial Differences and In-Hospital Mortality Associated With

Stress-Induced Cardiomyopathy During the COVID-19 Pandemic Moderated Poster Presenter: Banveet Kaur Khetarpal

4:49_PM Discussion 4:54_PM TCT 65: Characteristics of COVID-19 Patients With Thrombosis and

Impact on Clinical Outcomes Moderated Poster Presenter: Giorgio A. Medranda

5:01_PM Discussion 5:06_PM TCT 66: Choice and Outcomes of Left Main Coronary Disease

Revascularization Strategies in England Before and After the COVID-19 Era

Moderated Poster Presenter: Mohamed Osama Mohamed



5:13_PM Discussion 5:18_PM TCT 67: Mechanical Circulatory Support in COVID-19 Patients

Presenting With Myocardial Infarction: Analysis From the North American COVID-19 Myocardial Infarction Registry

Moderated Poster Presenter: Raviteja Guddeti 5:25_PM Discussion

_

Aortic Aneurysm and Dissection

Endovascular _

Moderated Challenging Cases



8:00 AM - 8:24 AM

Aortic Aneurysm and Dissection Moderators: D. Christopher Metzger Discussants: Somjot S. Brar, Tilo Kölbel

8:00_AM TCT 523: Transcatheter Management of Thoracic Aorta Pseudoaneurysm

Moderated Challenging Case Presenter: Tai Pham 8:07_AM Discussion 8:12_AM TCT 525: Expansion to Prevent Extension: Deployment of TAVR Valve

to Treat Iatrogenic Type A Aortic Dissection Moderated Challenging Case Presenter: Alexander E. Sullivan

8:19_AM Discussion _

Ventricular Remodeling and Septal Closure

Structural: Non-Valve _




9:15 AM - 10:15 AM

Ventricular Remodeling and Septal Closure Moderators: David A. Baran, Srihari S. Naidu Discussants: Jennifer Cowger

9:15_AM TCT 615: Decommissioning Of Left Ventricular Assist Device by Percutaneous Closure of Outflow Graft Using VSD occluder device and Amplatzer Vascular Plug

Moderated Challenging Case Presenter: Mohit Pahuja 9:22_AM Discussion 9:27_AM TCT 616: Endovascular Stenting for LVAD Outflow Tract Thrombosis

Moderated Challenging Case Presenter: Syed Haidry 9:34_AM Discussion 9:39_AM TCT 617: TCT 617: Less Invasive Ventricular Enhancement Procedure

(LIVE): First Case at HUMC Moderated Challenging Case Presenter: Sayf Altabaqchali

9:46_AM Discussion 9:51_AM TCT 618: Percutaneous Closure of an Apical Left Ventricular

Pseudoaneurysm Moderated Challenging Case Presenter: Rohit Vyas

9:58_AM Discussion 10:03_AM TCT 619: Trans-septal Pseudoaneurysm Closure After a Mechanical

Bentall Procedure—A Long and Winding Road to Success Moderated Challenging Case Presenter: Rafael Harari


Mitral Valve Disease and Intervention I

Structural: Valve _




11:00 AM - 11:48 AM

Mitral Valve Disease and Intervention I Moderators: Suzanne V. Arnold, Edwin Ho Discussants: Mayra Guerrero, Lindsey Prescher, Nishtha Sodhi

11:00_AM TCT 573: Challenging Transseptal Puncture for Percutaneous Mitral Paravalvular Leak Closure

Moderated Challenging Case Presenter: Charlene Lo Rohm 11:07_AM Discussion 11:12_AM TCT 574: Simultaneous Transcatheter Aortic and Mitral Valves

Replacements With Alcohol Septal Ablation Moderated Challenging Case Presenter: Matthew Douglas Saybolt

11:19_AM Discussion 11:24_AM TCT 576: A Rare and Fatal Complication of MitraClip

Moderated Challenging Case Presenter: Kanaan Mansoor 11:31_AM Discussion



11:36_AM TCT 577: Transcatheter Valve-in-Valve for Severe Mitral Prosthetic Stenosis: The Narrow Left Ventricular Outflow Tract May Fix Itself

Moderated Challenging Case Presenter: Soohyun Alice Chang 11:43_AM Discussion

_

Mitral Valve Disease and Intervention II

Structural: Valve _




12:00 PM - 12:36 PM

Mitral Valve Disease and Intervention II Moderators: Itsik Ben-Dor, Marc R. Katz Discussants: Mazen Albaghdadi, Peter Skarsgard

12:00_PM TCT 578: Transcatheter Mitral Valve-In-Valve Replacement In Bioprosthetic Mitral Valve Stenosis With Large Paravalvular Leak And Sub-Valvular Left Ventricular Pseudoaneurysm

Moderated Challenging Case Presenter: Vandan Upadhyaya 12:07_PM Discussion 12:12_PM TCT 580: A Case Of Severe Paravalvular Leak After Mitral Valve-In-

MAC Using Edwards Sapien 26mm Valve And A Hybrid Approach Moderated Challenging Case Presenter: Laith Derbas

12:19_PM Discussion 12:24_PM TCT 582: Percutaneous Transcatheter Mitral Valve Repair In Patient

With Dextrocardia And Cardiogenic Shock Moderated Challenging Case Presenter: Arvind Reddy Devanabanda


Aortic Valve Disease and Intervention I

Endovascular Structural: Valve _




1:00 PM - 1:48 PM

Aortic Valve Disease and Intervention I

1:00_PM TCT 526: Two Problems Same Time Moderated Challenging Case Presenter: Itsik Ben-Dor

1:07_PM Discussion 1:12_PM TCT 528: Surgical Resection of Prosthetic Valve Leaflets Under Direct

Vision with Valve-in-Valve TAVR (SURPLUS ViV) Moderated Challenging Case Presenter: Luigi Pirelli

1:19_PM Discussion 1:24_PM TCT 529: Simultaneous Transfemoral Transcatheter Aortic Valve

Implantation And Thoracic Endovascular Aortic Repair With Chimney Technique.

Moderated Challenging Case Presenter: Cristian Maximiliano Garmendia

1:31_PM Discussion 1:36_PM TCT 530: Successful Transcatheter Heart Valve Repositioning Using A

Double-Snare Technique Moderated Challenging Case Presenter: Victor Alfonso Jimenez

Jimenez Diaz 1:43_PM Discussion

_

Aortic Valve Disease and Intervention II

Structural: Valve _




2:30 PM - 3:06 PM

Aortic Valve Disease and Intervention II Moderators: Suzanne J. Baron, Fayaz Shawl Discussants: Anibal A. Damonte

2:30_PM TCT 531: Percutaneous Management of Self-Expanding Transcatheter Aortic Valve Embolization Into The Left Ventricle

Moderated Challenging Case Presenter: Carlos Andres Gonzalez-Lengua

2:37_PM Discussion 2:42_PM TCT 534: LVOT Injury After Transcatheter Aortic Valve Replacement

Moderated Challenging Case Presenter: Lily Chen 2:49_PM Discussion 2:54_PM TCT 535: Device Embolization of TAVR Valve In Ascending Aorta

Requiring Surgical Aortic Valve Replacement Moderated Challenging Case Presenter: Yash Jobanputra


Cardiogenic Shock and Hemodynamic Support

Coronary: CHIP Structural: Non-Valve Structural: Valve _






3:30 PM - 4:30 PM

Cardiogenic Shock and Hemodynamic Support Moderators: David A. Baran, Mauricio G. Cohen Discussants: Jennifer Cowger, Zachary George, Jacob Kriegel

3:30_PM TCT 536: Impella 5.5 as a Bridge To Repair in a Post-Infarct Ventricular Septal Defect

Moderated Challenging Case Presenter: Vidang Nguyen 3:37_PM Discussion 3:42_PM TCT 537: Dual Impella Support (Impella CP & RP Impella) for

Biventricular Cardiogenic Shock Just Hours Post-op After CABG With Significant Recovery

Moderated Challenging Case Presenter: Ramandeep Mand 3:49_PM Discussion 3:54_PM TCT 538: Percutaneous Decommissioning of a HeartWare Left

Ventricular Assist Device in a Patient With Myocardial Recovery Moderated Challenging Case Presenter: Carey D. Kimmelstiel

4:01_PM Discussion 4:06_PM TCT 539: Use of Percutaneous Intra-aortic Mechanical Circulatory

Support to Treat Acute Decompensated Heart Failure With Worsening Renal Function

Moderated Challenging Case Presenter: Mir Babar Basir 4:13_PM Discussion 4:18_PM TCT 540: LAVA-ECMO for Cardiogenic Shock and Acute Aortic

Regurgitation as a Bridge to Valve-in-Valve TAVR and PCI Moderated Challenging Case Presenter: Michael Chiang


Left Atrial Appendage





4:30 PM - 5:30 PM

Left Atrial Appendage Moderators: Elliott Michael Groves, Carlos E. Sanchez Discussants: Diego D. Grinfeld, Tilo Kölbel, Issam D. Moussa

4:30_PM TCT 563: Left Atrial Appendage Occlusion via Transhepatic Access in a Patient With Inferior Vena Cava Occlusion

Moderated Challenging Case Presenter: Ahmed El Shaer 4:37_PM Discussion 4:42_PM TCT 564: A New Perspective: Intracardiac Echocardiographic

Guidance for the Implantation of a Left Atrial Appendage Occluder Device (Watchman) with a Leadless Pacemaker (Micra)

Moderated Challenging Case Presenter: Kristen Nicole Brown 4:49_PM Discussion 4:54_PM TCT 565: Left Atrial Intramural Hematoma

Moderated Challenging Case Presenter: Aditya Kesari 5:01_PM Discussion 5:06_PM TCT 566: Residual Left Atrial Appendage Leak Following Percutaneous

Left Atrial Appendage Occlusion: An Arising Problem of The Emerging Procedure

Moderated Challenging Case Presenter: Chanavuth Kanitsoraphan 5:13_PM Discussion 5:18_PM TCT 567: Unusual Case of Severe Left Circumflex Coronary Artery

Stenosis Following Left Atrial Appendage Closure Moderated Challenging Case Presenter: Naeem K. Tahirkheli

5:25_PM Discussion THURSDAY, NOVEMBER 04, 2021 - _

Networking Reception

Networking Reception



7:30 PM - 9:00 PM

Networking Reception _

Industry Hub

Industry Hub



TCT 2021 | FRIDAY, NOVEMBER 05, 2021


8:00 AM - 5:30 PM

Industry Hub _

Virtual Exhibit Hall

Virtual Exhibit



8:00 AM - 5:30 PM


FRIDAY, NOVEMBER 05, 2021 - _

Structural Heart Disease #6 - Emory University, Atlanta, GA


Live Case Theater

FRIDAY, NOVEMBER 05, 2021 8:00 AM - 8:55 AM


8:00 AM - 8:55 AM

Structural Heart Disease #6 - Emory University, Atlanta, GA Live Case Moderators: Vinayak N. Bapat Live Case Co-Moderators: Adnan K. Chhatriwalla Live Case Discussants: Rebecca T. Hahn, Michael Joseph Rinaldi, David A. Wood Virtual Live Case Discussants: Jaffar M. Khan Live Case Operators: Vasilis Babaliaros, Adam B. Greenbaum

_

Coronary #4 - Royal Victoria Hospital, Belfast, Northern Ireland


Live Case Theater



9:00 AM - 10:00 AM

Coronary #4 - Royal Victoria Hospital, Belfast, Northern Ireland Live Case Moderators: Giora Weisz Live Case Co-Moderators: Simon Redwood Live Case Discussants: Andreas Baumbach, Kevin J. Croce, Robbert J. De Winter, Manel Sabate Live Case Operators: Colm Hanratty, Margaret B. McEntegart, James C. Spratt, Simon J. Walsh

9:00_AM Live Case Introduction of Coronary #4 - Royal Victoria Hospital, Belfast, Northern Ireland

Moderator: Giora Weisz 9:05_AM Coronary #4 - Royal Victoria Hospital, Belfast, Northern Ireland

_

Coronary #5 - Royal Victoria Hospital, Belfast, Northern Ireland

Coronary: CHIP Live Cases _

Live Case Theater



10:00 AM - 11:00 AM

Coronary #5 - Royal Victoria Hospital, Belfast, Northern Ireland Live Case Moderators: Cindy L. Grines Live Case Co-Moderators: Javier Escaned Live Case Discussants: Michael Foley, Nils Johnson, Nicholas Joseph Lembo, Megha Prasad Live Case Operators: Colm Hanratty, Margaret B. McEntegart, James C. Spratt, Simon J. Walsh

10:00_AM Live Case Introduction of Coronary #5 - Royal Victoria Hospital, Belfast, Northern Ireland

Moderator: Giora Weisz 10:05_AM Coronary #5 - Royal Victoria Hospital, Belfast, Northern Ireland

_

Coronary #6 - Emory University, Atlanta, GA


Live Case Theater



11:00 AM - 11:55 AM

Coronary #6 - Emory University, Atlanta, GA Live Case Moderators: Jeffrey W. Moses Live Case Co-Moderators: David E. Kandzari Live Case Discussants: Hector M. Garcia-Garcia Virtual Live Case Discussants: Marie-Claude Morice, Mitul P. Patel, Ashok Seth Live Case Operators: Wissam A. Jaber, William Nicholson, Stephane Rinfret

_

TCT 2021 Thomas J. Linnemeier Spirit of Interventional Cardiology Young Investigator Award – Extraordinary Group

Live Case Theater



FRIDAY, NOVEMBER 05, 2021 1:00 PM - 1:15 PM


1:00 PM - 1:15 PM

TCT 2021 Thomas J. Linnemeier Spirit of Interventional Cardiology Young Investigator Award – Extraordinary Group Presenters: Gregg W. Stone Finalists: Vasileios F. Panoulas, Jolanta M. Siller-Matula Virtual Finalists: Georg Goliasch

_

Hot Topic: How to Get Better as an Interventionalist – Learning From Complications, Supported through Unrestricted Educational Grants From Medtronic and Boston Scientific Corporation

Live Case Theater



1:15 PM - 2:15 PM

Hot Topic: How to Get Better as an Interventionalist – Learning From Complications, Supported through Unrestricted Educational Grants From Medtronic and Boston Scientific Corporation Moderators: Ajay J. Kirtane Virtual Moderators: William L. Lombardi Discussants: J. Aaron Grantham, Arasi Maran Virtual Discussants: Jennifer A. Tremmel

1:15_PM Historical Perspective on Cath Lab Complications: How Far We’ve Come

Virtual Lecturer: Cindy L. Grines 1:25_PM Roundtable Discussion

Virtual Discussant: Cindy L. Grines 1:30_PM Hemodynamic Collapse: Case and Algorithm

Virtual Lecturer: Craig A. Thompson 1:37_PM Roundtable Discussion

Guest Discussant: Craig A. Thompson 1:45_PM Avoiding and Managing Large Bore Access Complications: The

(New) Essential Skill for Interventionalists Virtual Lecturer: James M. McCabe

1:52_PM Roundtable Discussion 2:00_PM “Critical Appraisal of Complications: How to Get (and Allow

Yourself to Feel) Better” Lecturer: Sanjog Kalra

2:07_PM Roundtable Discussion and Wrap-up Guest Discussant: Sanjog Kalra

_

Hot Topic: Revascularization Guidelines – From “Certainty" (Class I and III) to "Probability" (Class II); Where Are the Gaps?

2:15 PM - 2:30 PM

Session 1. Revascularization vs. Medical Therapy in Chronic Coronary Syndromes Co-Moderators: Jacqueline E. Tamis-Holland Virtual Moderators: Paul Knaapen Discussants: Mladen I. Vidovich Virtual Discussants: Kenneth Chin, Ulf Landmesser, David J. Maron

2:15_PM Evidence Gaps: What’s Needed in the New Guidelines? Virtual Lecturer: Rasha Al-Lamee

2:21_PM Roundtable Discussion Virtual Discussant: Rasha Al-Lamee

2:30 PM - 2:45 PM

Session 2. Revascularization in Multivessel and Left Main Disease Moderators: David J. Moliterno, Jacqueline E. Tamis-Holland Discussants: Alfredo E. Rodriguez Virtual Discussants: Sidney C. Smith, Joanna J. Wykrzykowska

2:30_PM Evidence gaps: What’s Needed in the New Guidelines? Lecturer: David J. Cohen

2:36_PM Roundtable Discussion Discussant: David J. Cohen

2:45 PM - 3:00 PM

Session 3. Revascularization in STEMI and NSTEMI Moderators: Stephen G. Ellis Discussants: Jacqueline E. Tamis-Holland Virtual Discussants: Alice K. Jacobs, Sanjit S. Jolly, Sameer Mehta

2:45_PM Evidence Gaps: What’s Needed in the New Guidelines? Lecturer: Duane S. Pinto

2:51_PM Roundtable Discussion Discussant: Duane S. Pinto

_

Coronary #7 - University of Washington, Seattle, WA


Live Case Theater



3:00 PM - 3:55 PM

Coronary #7 - University of Washington, Seattle, WA Live Case Moderators: Margaret B. McEntegart Live Case Co-Moderators: J. Aaron Grantham Live Case Discussants: Khaldoon F. Alaswad, Allen Jeremias, Binita Shah Virtual Live Case Discussants: Craig A. Thompson Live Case Operators: Kathleen Kearney, William L. Lombardi, James M. McCabe



Live Case Theater





_

Coronary #8 - Humanitas Medical Center, Milan, Italy, This live case is sponsored by CRF and supported through unrestricted educational grants from Alvimedica and Concept Medical


Live Case Theater



4:00 PM - 5:00 PM

Coronary #8 - Humanitas Medical Center, Milan, Italy, This live case is sponsored by CRF and supported through unrestricted educational grants from Alvimedica and Concept Medical Live Case Moderators: Carlo Di Mario Live Case Co-Moderators: Shmuel Banai Live Case Discussants: J. Dawn Abbott, Giulio Guagliumi, Michael Haude, Thierry Lefevre Live Case Operators: Antonio Colombo

4:00_PM Live Case Introduction of Coronary #8 - Humanitas Medical Center, Milan, Italy

Moderator: Giora Weisz 4:05_PM Coronary #8 - Humanitas Medical Center, Milan, Italy

_

Structural Heart Disease #7 - Emory University, Atlanta, GA


Live Case Theater



5:00 PM - 5:55 PM

Structural Heart Disease #7 - Emory University, Atlanta, GA Live Case Moderators: Susheel K. Kodali Live Case Co-Moderators: Toby Rogers Live Case Discussants: Itsik Ben-Dor, Nirat Beohar Virtual Live Case Discussants: Marie-Annick Clavel, G. Burkhard Mackensen Live Case Operators: Vasilis Babaliaros, Adam B. Greenbaum, Jaffar M. Khan, Robert J. Lederman

_

Structural Heart Disease #8 - University of Washington, Seattle, WA


Live Case Theater

FRIDAY, NOVEMBER 05, 2021

6:00 PM - 6:55 PM

Structural Heart Disease #8 - University of Washington, Seattle, WA Live Case Moderators: Mayra Guerrero Live Case Co-Moderators: Steven F. Bolling Live Case Discussants: Karim Al-Azizi*, Tsuyoshi Kaneko, Michael Joseph Rinaldi Virtual Live Case Discussants: Isaac George Live Case Operators: William L. Lombardi, James M. McCabe

_

Coronary Hot Topic #5: CTO Essentials – Pathway and Tips and Tricks for Success, Part 1

Coronary: Core _




8:00 AM - 8:45 AM

Session 1: CTO PCI – The Basics Moderators: Dimitri Karmpaliotis, Margaret B. McEntegart Discussants: Ricardo Santiago Virtual Discussants: James C. Spratt, Masahisa Yamane

8:00_AM Introduction Intro/ Closing Presenter: Dimitri Karmpaliotis, Margaret B.

McEntegart 8:02_AM Indications for CTO PCI in 2021

Lecturer: Darshan Doshi 8:10_AM Roundtable Discussion

Discussant: Darshan Doshi 8:16_AM CTO PCI Crossing Algorithms

Lecturer: Anja Oksnes 8:24_AM Roundtable Discussion

Discussant: Anja Oksnes 8:30_AM How to Survive Complications of CTO PCI

Lecturer: Kevin J. Croce 8:38_AM Roundtable Discussion and Wrap-Up

Discussant: Kevin J. Croce _

Coronary Hot Topic #5: CTO Essentials – Pathway and Tips and Tricks for Success, Part 2

Coronary: Core _






6:00 PM - 6:55 PM




8:45 AM - 9:30 AM

Session 2: CTO PCI – The Controversies Moderators: Emmanouil S. Brilakis, Gerald S. Werner Discussants: Allison B. Hall, Anja Oksnes Virtual Discussants: Joseph A. Dens, Satoru Sumitsuji

8:45_AM Introduction Intro/ Closing Presenter: Emmanouil S. Brilakis, Gerald S. Werner

8:47_AM Debate 1: Extraplaque Wire Entry – Parallel Wire Is the Most Reliable Answer

Virtual Lecturer: Kambis Mashayekhi 8:53_AM Debate 1: Extraplaque Wire Entry – Device-Based Re-Entry Is the

Most Reliable Answer Lecturer: Arasi Maran

8:59_AM Debate 1: Extraplaque Wire Entry Discussion 9:09_AM Case Presentation: Introduction

Case Presenter: Allison B. Hall 9:14_AM Roundtable Discussion: How Would I Treat This Case? 9:24_AM Case Presentation: Outcome

Case Presenter: Allison B. Hall 9:29_AM Closing Thoughts & Adjourn

Intro/ Closing Presenter: Emmanouil S. Brilakis, Gerald S. Werner _

Structural Hot Topic #5: Mitral Transcatheter Edge-to-Edge Repair (TEER) – Clinical Insights and Controversies

Structural: Valve _




9:30 AM - 11:00 AM

Mitral Transcatheter Edge-to-Edge Repair (TEER) – Clinical Insights and Controversies Moderators: Paul Sorajja Virtual Moderators: Jörg Hausleiter Virtual Discussants: Stefan Anker, Patrick M. McCarthy, Ralph Stephan von Bardeleben

9:30_AM What’s New in the 2020 Valvular Heart Disease Guidelines for Primary and Secondary MR?

Lecturer: Robert O. Bonow 9:37_AM Emerging Data From the TVT and STS Mitral Registries

Lecturer: Paul Sorajja 9:44_AM New Insights From COAPT

Lecturer: Gregg W. Stone

9:51_AM TEER in Patients With Multivalvular Disease and/or RV Dysfunction Virtual Lecturer: Ralph Stephan von Bardeleben

9:58_AM Roundtable Discussion 10:08_AM Debate: Optimal Therapy for a Symptomatic 75-Year-Old With P2

Prolapse 10:08_AM Pro: TEER Is the Optimal Therapy TODAY!

Lecturer: Saibal Kar

10:13_AM Con: Surgery Is the Optimal Therapy TODAY!

Virtual Lecturer: Michael A. Acker

10:18_AM Roundtable Discussion 10:23_AM Optimal Medical Therapy (and CRT) Before TEER in Secondary MR:

What Regimen, What Duration? 10:23_AM My Perspectives: I

Lecturer: JoAnn Lindenfeld

10:28_AM *CONVERT TO DISCUSSION: My Perspectives: II

Virtual Lecturer: Milton Packer

10:33_AM Roundtable Discussion 10:39_AM Perspectives on TEER Trials in Primary MR: From Prohibitive to

Intermediate and Low Risk Virtual Lecturer: Joanna Chikwe

10:46_AM Perspectives on TEER Trials in Secondary MR (Control Groups, Enrollment Issues, and More)

Lecturer: Ori Ben-Yehuda 10:53_AM Roundtable Discussion and Wrap-up

_

Late-Breaking Clinical Trials Session II, In Collaboration With JAMA



FRIDAY, NOVEMBER 05, 2021 11:00 AM - 12:00 PM


11:00 AM - 12:00 PM

Late-Breaking Clinical Trials Session II, In collaboration With JAMA Moderators: Martin B. Leon Virtual Moderators: Gregory Curfman Discussants: Suzanne J. Baron, Robert O. Bonow, Sammy Elmariah, Neal S. Kleiman Virtual Discussants: Julinda Mehilli, Patrick T. O'Gara, Nicolo Piazza

11:00_AM SURTAVI: Five-Year Results From a Randomized Trial of TAVR vs. SAVR in Patients at Intermediate Surgical Risk



Virtual Presenter: Nicolas M. Van Mieghem 11:12_AM Discussion

Guest Discussant: Nicolas M. Van Mieghem 11:20_AM PARTNER 3: Two-Year Economic Outcomes From a Randomized Trial

of TAVR vs. SAVR in Patients at Low Surgical Risk Presenter: David J. Cohen

11:32_AM Discussion Guest Discussant: David J. Cohen

11:40_AM CHOICE-CLOSURE: A Randomized Trial of Plug-Based Versus Suture-Based Large-Bore Vascular Closure

Virtual Presenter: Mohamed Abdel-Wahab 11:52_AM Discussion

Guest Discussant: Mohamed Abdel-Wahab _

Late-Breaking Clinical Science Session II, In Collaboration With The European Heart Journal





1:00 PM - 2:00 PM

Late-Breaking Clinical Science Session 2, In Collaboration With The European Heart Journal Co-Moderators: Manesh R. Patel Virtual Moderators: Filippo Crea Discussants: Krzysztof Bartus, Anibal A. Damonte, Saibal Kar, Omar K. Khalique, Nadia R. Sutton Virtual Discussants: David R. Holmes Jr., Philippe Gabriel Steg

1:00_PM AMULET IDE: One-Year Device Closure From a Randomized Trial of Amulet Versus Watchman for Left Atrial Appendage Occlusion

Presenter: Dhanunjaya Lakkireddy 1:10_PM Discussion

Guest Discussant: Dhanunjaya Lakkireddy 1:15_PM PRAGUE-17: Three-Year Outcomes From a Randomized Trial of Left

Atrial Appendage Closure Versus Direct Acting Oral Anticoagulation in Patients With Atrial Fibrillation

Virtual Presenter: Pavel Osmancik 1:25_PM Discussion

Guest Discussant: Pavel Osmancik 1:30_PM MASTER-DAPT: A Randomized Trial of Abbreviated Antiplatelet

Therapy - Outcomes in High Bleeding Risk Patients With High Thrombotic and Ischemic Risk

Virtual Presenter: Pieter C. Smits 1:40_PM Discussion

Guest Discussant: Pieter C. Smits 1:45_PM STOPDAPT-2 Total Cohort: Pooled Results From Two Randomized

Trials of Clopidogrel Monotherapy After 1-Month DAPT Following PCI According to ACS Presentation and Ischemic and Bleeding Risk

Virtual Discussants: Ko YamamotoVirtual Presenters: Yuki Obayashi 1:55_PM Discussion

Guest Discussant: Yuki Obayashi, Ko Yamamoto _

Coronary Hot Topic #7: Outstanding Issues in STEMI Management – MV Disease, Myocardial Salvage, and More, Part 1

Coronary: Core _




2:00 PM - 2:30 PM

Revascularization in Multivessel Disease Moderators: Somjot S. Brar, George D. Dangas Discussants: Natalia Pinilla-Echeverri Virtual Discussants: Adrian P. Banning, Stefan K. James, Navin K. Kapur

2:00_PM Optimising Pharmacoinvasive Therapies for STEMI Patients Prior to PCI

Virtual Lecturer: Robert C. Welsh 2:06_PM Roundtable Discussion 2:10_PM Invasive Assessment of Non-Culprit Lesions in STEMI: How Can We

Assess Which Non-Culprit Lesions Needs Revascularization Prior to Hospital Discharge?

Virtual Lecturer: Shamir R. Mehta 2:18_PM Options for Immediate vs Staging Multivessel Revascularization in

STEMI Lecturer: Timothy D. Henry


Coronary Hot Topic #7: Outstanding Issues in STEMI Management – MV Disease, Myocardial Salvage, and More, Part 2

Coronary: Core _




2:30 PM - 3:00 PM

Infarct Size Reduction



2:30_PM Management of High Thrombus Burden: What Is the Role of Aspiration/ Intravenous Antipletelets/Intracoronary Lytic?

Lecturer: J. Dawn Abbott 2:36_PM How Do We Identify Patients With Microvascular Dysfunction and

Define Their Risk (Pressure Wire, Angiography, MRI)? Virtual Lecturer: Adrian P. Banning

2:42_PM Drug Therapy for No Re-Flow Lecturer: Somjot S. Brar

2:48_PM Special (Device/Drug) Approaches to Infarct Size Reduction Virtual Lecturer: Giovanni Luigi De Maria


Structural Hot Topic #4: TAVR Lifelong Management Journey With Aortic Stenosis

Structural: Valve _




3:00 PM - 4:00 PM

Lifelong Journey of the AS Patient Moderators: Michael J. Reardon Virtual Moderators: Bernard Prendergast Discussants: Adnan K. Chhatriwalla, Tsuyoshi Kaneko, Stephanie L. Mick Virtual Discussants: Helene Eltchaninoff

3:00_PM Introduction and Session Objectives Intro/ Closing Presenter: Michael J. Reardon

3:02_PM The Journey in Clinical Context (Case Presentation) Case Presenter: Itsik Ben-Dor

3:05_PM How Does the Data Inform Our Decision-making? Virtual Lecturer: Lars Sondergaard

3:15_PM Heart Team Discussion Guest Discussant: Itsik Ben-Dor, Lars Sondergaard

3:25_PM Short-term Priorities: Optimal Intervention for the Patient With Longer Life Expectancy

Lecturer: Amar Krishnaswamy 3:35_PM Heart Team Discussion

Guest Discussant: Amar Krishnaswamy 3:45_PM Longer-term Concerns: What Comes Next?

Lecturer: Tsuyoshi Kaneko 3:55_PM Conclusions and Take-home Messages

Intro/ Closing Presenter: Bernard Prendergast _

Structural Hot Topic #7: TAVR – Knowledge Gaps, Controversies, and Unresolved Issues, Part 1

Structural: Valve _




4:00 PM - 4:45 PM

Session I. TAVR Controversies Moderators: Samir R. Kapadia, Michael J. Reardon Discussants: Suzanne J. Baron, Megan Coylewright Virtual Discussants: Simon Redwood, Julia Seeger

4:00_PM Point-Counterpoint: Subclinical Leaflet Thrombosis 4:00_PM Unclear Clinical Significance

Virtual Lecturer: Lars Sondergaard

4:05_PM Clinically Significant Phenomenon With Consequences

Lecturer: Raj Makkar

4:10_PM Roundtable Discussion Guest Discussant: Raj Makkar, Lars

Sondergaard

4:15_PM Point-Counterpoint: Conduction Abnormalities After TAVR 4:15_PM Important Consideration for Valve Selection

Lecturer: Tamim M. Nazif

4:20_PM *CONVERT TO DISCUSSON: Minimal Impact on Clinical Endpoints

Virtual Lecturer: Hemal Gada

4:25_PM Roundtable Discussion Guest Discussant: Hemal Gada, Tamim M.

Nazif

4:30_PM Point-Counterpoint: Cerebral Protection 4:30_PM Not Indicated for Routine TAVR

Lecturer: John K. Forrest

4:35_PM Routine Use Is Entirely Justifiable Lecturer: Axel Linke

4:40_PM Roundtable Discussion and Wrap-up Guest Discussant: John K. Forrest, Axel Linke

_

Structural Hot Topic #7: TAVR – Knowledge Gaps, Controversies, and Unresolved Issues, Part 2

Structural: Valve _






4:45 PM - 5:30 PM

Session II. TAVR Knowledge Gaps Moderators: Kendra J. Grubb, Samir R. Kapadia Discussants: Stephanie L. Mick Virtual Discussants: Thomas Modine, Patrick T. O'Gara

4:45_PM Rationale of Earlier AS Treatment: Asymptomatic Severe AS and Moderate AS

Virtual Lecturer: Nicolas M. Van Mieghem 4:51_PM Roundtable Discussion

Virtual Discussant: Nicolas M. Van Mieghem 4:56_PM Understanding SVD and BVF: VARC-3 and European Definitions

Virtual Lecturer: Philippe Pibarot 5:02_PM Roundtable Discussion

Guest Discussant: Philippe Pibarot 5:07_PM Evidence-Based Antiplatelet and Antithrombotic Therapy for

TAVR Virtual Lecturer: Stephan Windecker

5:13_PM Roundtable Discussion Guest Discussant: Stephan Windecker

5:18_PM Early Discharge After TAVR Lecturer: Amar Krishnaswamy

5:24_PM Roundtable Discussion and Wrap-up Discussant: Amar Krishnaswamy

_

Coronary Hot Topic #8: Balancing the Full Spectrum of Bleeding and Ischemic Risk in PCI, Part 1

Coronary: Core _




5:30 PM - 6:30 PM

Session 1: Risk Prediction and Management Virtual Moderators: Rasha Al-Lamee, Marie-Claude Morice Virtual Discussants: Mirvat Alasnag, Roisin Colleran, Marco Valgimigli

5:30_PM Introduction Intro/ Closing Presenter: Marie-Claude Morice

5:31_PM Ischemic Risk Prediction and Stratification After PCI: The State of the Art in 2021

Lecturer: Gennaro Giustino 5:39_PM Bleeding Risk Prediction and Stratification After PCI: The State of

the Art in 2021

Virtual Lecturer: Sunil V. Rao 5:47_PM Roundtable Discussion 6:01_PM Case Presentation: A Patient at High Ischemic and Bleeding Risks

Virtual Case Presenter: Angelo Quagliana 6:06_PM Debate: Follow the Ischemic Risk, Prolong DAPT!

Virtual Lecturer: Robert W. Yeh 6:12_PM Debate: Follow the Bleeding Risk, Shorten DAPT!

Lecturer: Dominick J. Angiolillo 6:18_PM Debate Discussion: Follow the Risk 6:28_PM Closing Thoughts & Adjourn

Virtual Moderator: Marie-Claude Morice _

Coronary Hot Topic #8: Balancing the Full Spectrum of Bleeding and Ischemic Risk in PCI, Part 2

Coronary: Core _




6:30 PM - 7:00 PM

Session 2: Update on Latest Evidence on High Bleeding Risk Patients Moderators: Usman Baber Virtual Moderators: Rasha Al-Lamee Virtual Discussants: Robert A. Byrne, Davide Capodanno, Mitchell W. Krucoff

6:30_PM Introduction 6:31_PM DAPT Duration in High Bleeding Risk Patients: Lessons From

Registries Virtual Lecturer: Davide Cao

6:38_PM DAPT Duration in High Bleeding Risk Patients: Lessons From RCTs Virtual Lecturer: Marco Valgimigli

6:45_PM DAPT Duration in the Afib Patient: Where Do We Stand? Virtual Lecturer: Renato D. Lopes

6:52_PM Roundtable Discussion and Wrap-up _

Satellite: A Heart Team Walks Into a Conference Room...

Satellites _

Innovation Theater





6:30 AM - 7:30 AM

A Heart Team Walks Into a Conference Room...

6:30_AM The Heart Team Today Discussants: Guilherme Attizzani, Antonie Keller, Neal S.

KleimanSatellite Presenters: Joshua Rovin 6:40_AM Same Patient, Different Treatment Approach?

Discussants: Guilherme Attizzani, Antonie Keller, Joshua RovinSatellite Presenters: Neal S. Kleiman

6:53_AM A Tale of Two Guidelines: ESC vs. AHA/ACC Discussants: Guilherme Attizzani, Neal S. Kleiman, Joshua

RovinSatellite Presenters: Antonie Keller 7:05_AM It All Comes Down to Durability

Discussants: Antonie Keller, Neal S. Kleiman, Joshua RovinSatellite Presenters: Guilherme Attizzani

7:20_AM Discussion Discussant: Guilherme Attizzani, Antonie Keller, Neal S. Kleiman,

Joshua Rovin _

Featured Clinical Research Session II

Innovation Theater



8:00 AM - 9:00 AM

TCT 2021 Featured Clinical Research Session II Co-Moderators: John D. Carroll Virtual Moderators: Sanjit S. Jolly Discussants: Morton J. Kern, Akiko Maehara Virtual Discussants: Carlo Di Mario, Javier Escaned, Vijay Kunadian, Francesco Prati

8:00_AM CAD III: One-year Outcomes of Intravascular Lithotripsy for Treatment of Severely Calcified Coronary Arteries

Lecturer: Matthew J. Price 8:08_AM Discussion

Guest Discussant: Jonathan Michael Hill 8:12_AM CHEETAH: Multicenter Study of Continuous Mechanical Aspiration

Thrombectomy Prior to PCI in Patients With High Thrombus Burden Presenter: Santhosh Jay Mathews

8:20_AM Discussion Guest Discussant: Santhosh Jay Mathews

8:24_AM ILIAS: Multicenter Study of Five-year Clinical Outcomes According to FFR and CFR Assessments and Revascularization Decisions

Virtual Presenter: Tim P. Van de Hoef 8:32_AM Discussion

Guest Discussant: Tim P. Van de Hoef 8:36_AM FFR REACT: A Randomized Trial of FFR-Guided PCI Optimization by

IVUS Versus No Optimization

Virtual Presenter: Joost Daemen 8:44_AM Discussion

Guest Discussant: Joost Daemen 8:48_AM AUGUSTUS: A Randomized Trial of Antithrombotic Strategies in

Patients With Atrial Fibrillation: 4-Way Outcomes Analysis Virtual Presenter: Otavio Berwanger

8:56_AM Discussion Guest Discussant: Otavio Berwanger

_

SCAI at TCT: New Directions in Cardiogenic Shock

Innovation Theater



9:00 AM - 10:00 AM

SCAI at TCT: New Directions in Cardiogenic Shock Moderators: Timothy D. Henry, Srihari S. Naidu Discussants: Marc D. Feldman Virtual Discussants: Jacob C. Jentzer, Mitchell W. Krucoff, Pascal Vranckx

9:00_AM SCAI SHOCK Classification Validation Studies: Results and Insights Virtual Lecturer: Jacob C. Jentzer

9:10_AM Featured Lecture: The SCAI SHOCK Classification Update - Rationale and Modifications

Lecturer: Srihari S. Naidu 9:20_AM CSRC Cardiogenic Shock Program: Working Groups and Progress

Virtual Lecturer: Mitchell W. Krucoff 9:27_AM Ongoing Cardiogenic Shock Trials in Europe

Lecturer: Holger Thiele 9:37_AM Ongoing/Planned Cardiogenic Shock Trials in the US

Lecturer: William W. O'Neill 9:45_AM Roundtable Discussion With Audience Q&A

_

Coronary Hot Topic #6: Cardiogenic Shock and Cardiac Arrest Revisited

Coronary: Core _

Innovation Theater





10:00 AM - 11:00 AM

Cardiogenic Shock and Cardiac Arrest Revisited Moderators: Binita Shah Virtual Discussants: Navin K. Kapur

10:00_AM Cardiogenic Shock and Cardiac Arrest Virtual Discussants: Tanveer RabGuest Discussants: Sandeep

Nathan, Ranya Sweis 10:00_AM Cardiogenic Shock and Cardiac Arrest State-

of-the-Art: Risk Scores and Evidence-Based Management

Lecturer: Mir Babar Basir


10:24_AM Debate 1: Should Multivessel PCI Be Performed Acutely in All or Many Patients With Cardiogenic Shock?

Guest Discussant: J. Dawn Abbott, Jeffrey W. Moses, Srihari S. Naidu 10:24_AM Con: Should Multivessel PCI Be Performed

Acutely in All or Many Patients With Cardiogenic Shock?

Lecturer: Holger Thiele

10:29_AM Pro: Should Multivessel PCI Be Performed Acutely in All or Many Patients With Cardiogenic Shock?

Lecturer: William W. O'Neill


10:42_AM Debate 2: Is Impella CP the First-line MCS of Choice for Acute MI and Cardiogenic Shock?

Virtual Discussants: Cindy L. GrinesGuest Discussants: Daniel Burkhoff

10:42_AM Pro: Is Impella CP the First-line MCS of Choice for Acute MI and Cardiogenic Shock?

Virtual Lecturer: A. Reshad Garan

10:47_AM Con: Is Impella CP the First-line MCS of Choice for Acute MI and Cardiogenic Shock?

Lecturer: Sandeep Nathan

10:52_AM Roundtable Discussion and Wrap-Up

_

Emerging Technological Trends II: Cath Lab of the Future and Emerging PCI Tools


Innovation Theater



11:00 AM - 12:00 PM

Emerging Technological Trends II: Cath Lab of the Future and Emerging PCI Tools

11:00_AM Electroanatomical Navigation for Arterial Stenting with Near-Zero X-Ray or Iodine-Based Contrast Medium: Insights from Experimental Data

Lecturer: Jean-Francois Dorval 11:07_AM Scanning Laser Angioscopy: A New High-Resolution Multimodal

Platform for Intravascular Diagnosis and Therapy Lecturer: Luis Savastano

11:14_AM REDEFINE: A Prospective, Randomized Evaluation of the ControlRad System to Reduce Radiation Exposure During Cardiac Catheterization Procedures

Lecturer: Simon R. Dixon 11:21_AM Roundtable Discussion 11:30_AM A Novel Sirolimus-Eluting Iron-Based Bioresorbable Scaffold

Implantation in Single De Novo Coronary Lesions: Two-Year Clinical and Imaging Outcomes from the First in Man Study (IBS-FIM)

Virtual Lecturer: Runlin Gao 11:37_AM Laser Balloon Calcium Fracture in Calcified Human Coronary Arteries

Lecturer: Marc D. Feldman 11:44_AM First-in-Man Use of the NeVa™ Stent Retriever in Patients with

Acute Coronary Syndromes Virtual Lecturer: Angelo Quagliana

11:51_AM Roundtable Discussion _

FDA Town Hall Session IV: Tricuspid Valve Interventions


Innovation Theater



1:00 PM - 1:30 PM

Tricuspid Valve Interventions Moderators: Rebecca T. Hahn Virtual Moderators: Jaime Raben Discussants: Scott Lim, Georg Nickenig, Paul Sorajja Virtual Discussants: Ankurita Datta, Ted E. Feldman, Meir Shinnar

1:00_PM Tricuspid Valve Interventions - Adding Quality of Life to Years, from Industry Perspective

Lecturer: Suzanne V. Arnold 1:05_PM Tricuspid Valve Interventions - Adding Quality of Life to Years, from

FDA Perspective Virtual Lecturer: Mauro Moscucci


FDA Town Hall Session V: Heart Failure Interventions


Innovation Theater





1:30 PM - 2:00 PM

Heart Failure Interventions Moderators: William T. Abraham, Gregg W. Stone Discussants: Daniel Burkhoff Virtual Discussants: Marvin A. Konstam, Christopher O'Connor, Ileana L. Pina

1:30_PM Heart Failure Interventions – Defining Optimal Medical Therapy in a Device Trial, From Academic Perspective

Lecturer: William T. Abraham 1:35_PM Heart Failure Interventions – Defining Optimal Medical Therapy in a

Device Trial, From FDA Perspective Virtual Lecturer: Meir Shinnar


FDA Town Hall Session VI: Left Atrial Appendage Interventions


Innovation Theater



2:00 PM - 2:30 PM

Left Atrial Appendage Interventions Moderators: Dhanunjaya Lakkireddy Virtual Moderators: Rachel Neubrander Discussants: Dominic Allocco, Saibal Kar Virtual Discussants: Shephal Doshi, Kan Fang, Vivek Y. Reddy

2:00_PM Left Atrial Appendage Interventions – Closing the Key Evidence Gaps to Move the Field Forward, From Academic Perspective

Virtual Lecturer: Vivek Y. Reddy 2:05_PM Left Atrial Appendage Interventions – Closing the Key Evidence Gaps

to Move the Field Forward, From FDA Perspective Virtual Lecturer: Kan Fang


FDA Town Hall Session VII: Digital Health Apps


Innovation Theater



2:30 PM - 3:00 PM

Digital Health Apps Virtual Moderators: Tariq Ahmad, Jessica Paulsen Virtual Discussants: Mintu P. Turakhia, George Van Hare, Niraj Varma

2:30_PM Digital Health Apps in Cardiovascular Device Trials, a Clinician's Perspective

Virtual Lecturer: Mintu P. Turakhia 2:35_PM Digital Health Apps in Cardiovascular Device Trials, From FDA

Perspective Virtual Lecturer: George Van Hare


Emerging Technological Trends III: Interventional Heart Failure and Neuromodulation Therapies

Innovation Theater



3:00 PM - 4:00 PM

Emerging Technological Trends III: Interventional Heart Failure and Neuromodulation Therapies Moderators: Jerry D. Estep, Marat Fudim Discussants: Mazen Albaghdadi, Robert S. Schwartz Virtual Discussants: James E. Udelson

3:00_PM Interventional Heart Failure 3:00_PM Alleviant System: Implant-Free Interatrial

Shunt Creation for Heart Failure Lecturer: Jacob Kriegel

3:07_PM Implant-less Percutaneous Atrial Shunt-Catheter (PAS-C) System: InterShunt

Lecturer: Harlee Sorkin

3:14_PM Biventricular Non-Blood Contacting Cardiac Assist Device for Acute Heart Failure Syndrome (CorInnova)

Lecturer: William C. Altman


3:30_PM Neuromodulation Therapies and Pacemakers



3:30_PM Catheter-Based Greater Splanchnic Nerve Ablation in Chronic Heart Failure: Preserved vs. Reduced Left Ventricular Ejection Fraction (Axon Therapies)

Virtual Lecturer: Vivek Y. Reddy

3:37_PM Cardiac Neuromodulation Therapy Effect on Systolic Blood Pressure and Pulse Pressure in Patients with Isolated Systolic Hypertension In A Randomized Double-Blind Study Together With Long Term Follow Up Results (Backbeat Medical)

Lecturer: Daniel Burkhoff

3:44_PM Creative Temporary Pacemaker Strategies for Structural Heart Procedures

Virtual Lecturer: David Daniels

3:49_PM A Validation Study of the OpSens LV Pressure Guidewire

Lecturer: Philippe Genereux


_

Structural Hot Topic #6: Mitral Valve Repair – Beyond Leaflet Grasping

Structural: Valve _

Innovation Theater



4:00 PM - 5:00 PM

Mitral Valve Repair: Beyond Leaflet Grasping Moderators: Anita W. Asgar, Susheel K. Kodali Discussants: Ulrich Schäfer, Firas Zahr Virtual Discussants: Isaac George, Eberhard Grube

4:00_PM Limitations of TEER and Justification for Additional Transcatheter Repair Concepts

Lecturer: Georg Nickenig 4:07_PM Roundtable Discussion 4:11_PM Annular Repair Strategies (Millipede, Carillon, Cardioband)

Lecturer: Jason H. Rogers 4:18_PM Leaflet Augmentation Technologies (Half-Moon, Polares, Dura-Sutra)

Lecturer: Firas Zahr 4:25_PM Roundtable Discussion 4:33_PM Chordal Repair Approaches (Harpoon, Pipeline, Chordart, Neochord,

CardioMech)

Lecturer: Anita W. Asgar 4:40_PM Roundtable Discussion 4:44_PM The Future of Mitral Valve Repair: Combination or Sequential

Therapies Virtual Lecturer: Ralph Stephan von Bardeleben

4:51_PM Roundtable Discussion 4:55_PM MR Case Presentation and Heart Team Discussion and Wrap-Up

Virtual Lecturer: Anu Tunuguntla _

Structural Hot Topic #8: TMVR (Replacement) – Current Clinical Indications, Potential Technical Advantages, and Limitations

Structural: Valve _

Innovation Theater



5:00 PM - 6:00 PM

TMVR (Replacement): Current Clinical Indications, Potential Technical Advantages, and Limitations Moderators: Paul Sorajja, Molly Szerlip Discussants: Mayra Guerrero Virtual Discussants: Howard C. Herrmann, Nicolo Piazza

5:00_PM Introduction Intro/ Closing Presenter: Paul Sorajja

5:02_PM Where the Roads Cross: A High Surgical Risk Case With Mitral Anatomy Suitable for Repair

Case Presenter: Anita W. Asgar 5:07_PM Roundtable Heart Team Discussion 5:17_PM Reconciling Anatomical Indications With TMVR Technical

Advantages and Limitations Lecturer: Brian K. Whisenant

5:24_PM Roundtable Heart Team Discussion 5:30_PM Where the Road Gets Bumpy: A Hostile Anatomy Case for TMVR

Virtual Case Presenter: Vinod H. Thourani 5:37_PM Roundtable Heart Team Discussion 5:45_PM Defining the Path Forward for TMVR: Successfully Treated MAC

Case Virtual Lecturer: Gorav Ailawadi

5:52_PM Roundtable Heart Team Discussion 5:59_PM Closing Remarks & Adjourn

_

Best of Challenging Cases

Innovation Theater





6:00 PM - 7:12 PM

Best of Challenging Cases Moderators: Stephen G. Ellis Virtual Moderators: Bimmer E. Claessen Discussants: David L. Fischman Virtual Discussants: Olivier F. Bertrand, David A. Cox

6:00_PM Percutaneous Retrieval of a Malfunctioning WATCHMAN Device Presenter: Coty W. Jewell

6:07_PM Discussion Discussant: Coty W. Jewell

6:12_PM Total Percutaneous Revascularization Of The Hand To Treat Refractory Digital Ischemia In Advanced Systemic Sclerosis

Presenter: Salman Arain 6:19_PM Discussion

Discussant: Salman Arain 6:24_PM A Square Peg in a Round Hole - Bailout Valve-in-Valve Transcatheter

Prosthetic Mitral Valve Replacement for Critical Mitral Stenosis on Extracorporeal Membrane Oxygenation and Subsequent Paravalvular Leak Plugging

Virtual Presenter: Tom Meredith 6:31_PM Discussion

Guest Discussant: Tom Meredith 6:36_PM Successful Percutaneous Mechanical Thrombectomy After Failure of

Systemic Thrombolytics to Treat Intermediate-High-Risk Bilateral Pulmonary Embolism in a COVID-19 Patient

Presenter: Samy Selim 6:43_PM Discussion

Discussant: Samy Selim 6:48_PM Transcathter Closure of an Acquired Aortopulmonary Window After

Surgical Aortic Valve Replacement Due to Endocarditis: A 3D Computer-based Prototyping Case Report

Virtual Presenter: Vinicius Daher Vaz 6:55_PM Discussion

Guest Discussant: Vinicius Daher Vaz 7:00_PM Emergent Transseptal Transcatheter Mitral Valve-in-Valve

Implantation in Patient With Cardiogenic Shock Presenter: Prasanthi Yelavarthy

7:07_PM Discussion Discussant: Prasanthi Yelavarthy

_

Satellite: Advancing Coronary Intervention with Sirolimus-Coated Balloons

Satellites _




8:00 AM - 9:00 AM

Advancing Coronary Intervention with Sirolimus-Coated Balloons

8:00_AM Session Objectives and Opening Remarks Satellite Presenter: Martin B. Leon

8:01_AM MagicTouch SCB with Nanolute Technology: Pre-clinical insights and rationale

Moderators: Martin B. LeonVirtual Satellite Presenters: Aloke Finn 8:08_AM Discussion

Moderators: Martin B. LeonDiscussants: Antonio ColomboVirtual Discussants: Sandeep Basavarajaiah, Bernardo Cortese, Aloke Finn, Patrick W. Serruys

8:11_AM Be Safe; Be Smart: Where to use DCB in current PCI practice? Moderators: Martin B. LeonVirtual Satellite Presenters: Antonio

Colombo 8:19_AM Discussion

Moderators: Martin B. LeonDiscussants: Antonio ColomboVirtual Discussants: Sandeep Basavarajaiah, Bernardo Cortese, Aloke Finn, Patrick W. Serruys

8:23_AM The role of sirolimus-coated balloon for the near future: Where shall we go

Moderators: Martin B. LeonVirtual Satellite Presenters: Bernardo Cortese

8:31_AM Discussion Moderators: Martin B. LeonDiscussants: Antonio ColomboVirtual

Discussants: Sandeep Basavarajaiah, Bernardo Cortese, Aloke Finn, Patrick W. Serruys

8:35_AM Real world case experience and clinical outcomes with the MagicTouch Sirolimus Coated Balloon

Moderators: Martin B. LeonVirtual Satellite Presenters: Sandeep Basavarajaiah

8:43_AM Discussion Moderators: Martin B. LeonDiscussants: Antonio ColomboVirtual


8:47_AM The MAGICAL trial – Insights from the upcoming US IDE DCB study Satellite Presenter: Martin B. Leon

8:52_AM Roundtable Discussion Moderators: Martin B. LeonDiscussants: Antonio ColomboVirtual


_

Satellite: Advanced PCI Techniques in Real World Cases

Satellites _






9:00 AM - 10:00 AM

Advanced PCI Techniques in Real World Cases

9:00_AM Welcome & Introduction Moderator: Rhian E. Davies

9:03_AM Large Sheath Access and Closure Virtual Satellite Presenter: Ehtisham Mahmud

9:15_AM Panel Discussion Moderators: Rhian E. DaviesDiscussants: Arasi Maran, Duane S.

PintoVirtual Discussants: Ehtisham Mahmud 9:20_AM Radial in Complex PCI

Satellite Presenter: Duane S. Pinto 9:35_AM Panel Discussion

Moderators: Rhian E. DaviesDiscussants: Arasi Maran, Duane S. PintoVirtual Discussants: Ehtisham Mahmud

9:40_AM Contemporary CTO - ADR Techniques Satellite Presenter: Arasi Maran

9:55_AM Panel Discussion Moderators: Rhian E. DaviesDiscussants: Arasi Maran, Duane S.

PintoVirtual Discussants: Ehtisham Mahmud _

Satellite: Advancing the Future of Intracardiac Echo in Structural Heart Disease Procedures

Satellites _




10:00 AM - 11:00 AM

Advancing the Future of Intracardiac Echo in Structural Heart Disease Procedures

10:00_AM Welcome and Introduction Video Satellite Presenter: Carlos E. Sanchez

10:02_AM Left Atrial Appendage Closure Procedure Satellite Presenter: Carlos E. Sanchez

10:15_AM AcuNav Volume ICE for MitraClip Virtual Satellite Presenter: Gagan D. Singh

10:30_AM 4D ICE for Tomorrow Virtual Satellite Presenter: Vaikom Mahadevan

10:50_AM Q&A Moderators: Carlos E. SanchezVirtual Discussants: Vaikom

Mahadevan, Gagan D. Singh _

Satellite: New Insights on the Consistency of Coronary IVL Data

Satellites _




11:00 AM - 12:00 PM

New Insights on the Consistency of Coronary IVL Data

11:00_AM Introduction & MOA Overview Satellite Presenter: Ziad A. Ali

11:12_AM Disrupt CAD III 1yr Data Satellite Presenter: Matthew J. Price

11:24_AM Disrupt CAD Pooled Eccentric vs Concentric Analysis Satellite Presenter: Ziad A. Ali

11:36_AM Disrupt CAD Pooled Nodular Calcium Analysis Satellite Presenter: Akiko Maehara

11:48_AM Disrupt CAD Pooled Female vs Male Analysis Satellite Presenter: Alexandra J. Lansky

_

Satellite: Coronary Aspiration in 2021: Results of the Cheetah Study

Satellites _




1:00 PM - 2:00 PM

Coronary Aspiration in 2021: Results of the Cheetah Study

1:00_PM Power Aspiration: Key Results from The Cheetah Study Discussants: D. Christopher Metzger, Sahil A. ParikhSatellite

Presenters: Santhosh Jay Mathews 1:20_PM Coronary Aspiration in My Practice: Case Presentations

Discussants: Santhosh Jay Mathews, Sahil A. ParikhSatellite Presenters: D. Christopher Metzger

1:40_PM Continuous Mechanical Aspiration: Myocardial Perfusion and the Prevention of No Reflow

Discussants: Santhosh Jay Mathews, D. Christopher MetzgerSatellite Presenters: Sahil A. Parikh

_

Satellite: Transforming Hypertension Treatment: Updates on MEDTRONIC's SPYRAL-HTN Global Clinical Trial Program

Satellites _




2:00 PM - 3:00 PM

Transforming Hypertension Treatment: Updates on MEDTRONIC's SPYRAL-HTN Global Clinical Trial Program



2:00_PM Introduction & Objectives Moderator: Raymond R. Townsend

2:05_PM Leading with Level 1 Evidence: Data from SPYRAL-HTN Clinical Program

Virtual Satellite Presenter: Michael Böhm 2:15_PM Real World Experience: Insights from the Global SYMPLICITY Registry

Virtual Satellite Presenter: Flavio L. Ribichini 2:25_PM Pre-Clinical Evidence: Radiofrequency RDN Effectiveness and

Durability Virtual Satellite Presenter: Andrew Sharp

2:35_PM Latest Evidence in the SPYRAL-HTN Clinical Program Satellite Presenter: Raymond R. Townsend

2:45_PM Question & Answers Moderator: Raymond R. Townsend

2:55_PM Key Learnings & Conclusions Moderator: Raymond R. Townsend

_

Innovation @ TCT World Connect: Innovation Trends in TAVR Technologies, Sponsored by CRF

Innovation _




3:00 PM - 4:00 PM

Innovation Trends in TAVR Technologies, Sponsored by CRF Moderators: Axel Linke, Oscar A. Mendiz Discussants: Philippe Genereux, Susheel K. Kodali Virtual Discussants: Federico De Marco, Ariel Finkelstein

3:00_PM Innovation in the TAVR Space: Remaining Challenges and Opportunities

Virtual Lecturer: Eberhard Grube 3:08_PM Roundtable Discussion 3:12_PM Evaluation of the OpSens OptoWire III and its Novel TAVR Algorithm

to Measure Pressure Gradient before and After TAVR Compared With Hemodynamic Value Derived by Catheterization and Echocardiogram

Lecturer: Philippe Genereux 3:19_PM A Pressure Wire for Valve Implantation and Continuous

Hemodynamic Monitoring During TAVR Procedures: Initial Experience with the SavvyWire

Virtual Lecturer: Josep Rodés-Cabau 3:25_PM DurAVR THV: A Novel 3D Single Piece Valve Designed for Improved

Durability and Hemodynamics Lecturer: Samir R. Kapadia

3:32_PM Roundtable Discussion 3:39_PM First Dedicated Transcatheter Leaflet Splitting Device From Bench

to FIH (ShortCut) Lecturer: Susheel K. Kodali

3:46_PM AorticLab GEMINI - Functional Recovery of Stenotic Aortic Valve With A Double Ultrasound Wave Effect

Virtual Lecturer: Federico De Marco 3:53_PM Roundtable Discussion

_

Satellite: Balancing Ischemic and Bleeding Risk with Antiplatelet Therapy: Personalizing Treatment to Optimize Outcomes

Satellites _




4:00 PM - 5:00 PM

Balancing Ischemic and Bleeding Risk with Antiplatelet Therapy: Personalizing Treatment to Optimize Outcomes

4:00_PM Introduction Satellite Presenter: George D. Dangas

4:05_PM Antiplatelet Therapy for Patients with Diabetes Undergoing PCI Virtual Satellite Presenter: Deepak L. Bhatt

4:15_PM When to Shorten DAPT: Key Messages Satellite Presenter: George D. Dangas

4:25_PM Finding the Sweet Spot: Balancing Reducing Ischemic Risk and Reducing Bleeding Risk with Antiplatelet Therapy

Virtual Satellite Presenter: Deepak L. Bhatt 4:30_PM Case #1: Bleeding and Ischemic Complications from the EXCEL

Trial Satellite Presenter: Gregg W. Stone

4:45_PM Case #2: Antiplatelet Therapy Disruption Challenges After Stenting Satellite Presenter: George D. Dangas

_

Satellite: Real-world, Lytic-free Evidence for Treatment of Pulmonary Embolism with Inari Medical’s FlowTriever

Satellites _






5:00 PM - 6:00 PM

Real-world, Lytic-free Evidence for Treatment of Pulmonary Embolism with Inari Medical’s FlowTriever

5:00_PM Introduction to Inari Medical Satellite Presenter: Thomas Tu

5:03_PM Case Presentation Satellite Presenter: Sanjum S. Sethi

5:10_PM Acute and Long-term Improvements Following FlowTriever Mechanical Thrombectomy in Pulmonary Embolism Patients:Six-Month Results From the FLASH Registry

Satellite Presenter: Catalin Toma 5:25_PM The Future of the PE space

Moderators: Thomas TuDiscussants: Wissam A. Jaber, Sanjum S. Sethi, Catalin Toma

5:35_PM PEERLESS RCT Study Review Satellite Presenter: Wissam A. Jaber

5:50_PM Q&A/Panel Discussion Moderators: Thomas TuDiscussants: Wissam A. Jaber, Sanjum S. Sethi,

Catalin Toma _

Aortic Stenosis, Aortic Insufficiency, and TAVR II

Structural: Valve _

Moderated Posters



8:00 AM - 8:48 AM

Aortic Stenosis, Aortic Insufficiency, and TAVR II Moderators: João L. Cavalcante, Brijeshwar Maini Discussants: Karim Al-Azizi*, Elliott Michael Groves, Uri Landes

8:00_AM TCT 46: Deformation of Transcatheter Aortic Valve Prostheses: Implications for Hypo-Attenuating Leaflet Thickening

Moderated Poster Presenter: Miho Fukui 8:07_AM Discussion 8:12_AM TCT 48: Incidence and Outcomes of Atrial Fibrillation in Patients

Undergoing TAVR vs SAVR: Experience From SURTAVI and Low Risk Randomized Studies

Moderated Poster Presenter: Amit N. Vora 8:19_AM Discussion 8:24_AM TCT 49: Incidence of Permanent Pacemaker Implantation Using the

Cusp Overlap Technique: A Large Single-Center Analysis Moderated Poster Presenter: Ahmed Aladham

8:31_AM Discussion

8:36_AM TCT 51: Complete Cerebral Protection via Left Radial Approach during Transcatheter Aortic Valve Replacement – Results from the PROTEMBO C Trial

Moderated Poster Presenter: Tobias Schmidt 8:43_AM Discussion

_

Mitral Disease and Intervention

Structural: Valve _

Moderated Posters



9:15 AM - 10:27 AM

Mitral Disease and Intervention Moderators: Steven F. Bolling, Neil J. Weissman Discussants: Michael Joseph Rinaldi, Nishtha Sodhi, Poonam Velagapudi

9:15_AM TCT 102: Assessing the Risk of Neo-Left Ventricular Outflow Tract Obstruction in Transcatheter Mitral Valve Replacement: Are We Treating All the Patients That Can be Treated?

Moderated Poster Presenter: Keshav Kohli 9:22_AM Discussion 9:27_AM TCT 103: Safety and Effectiveness of Transcatheter Edge-to-Edge

Repair With MitraClip™ in Atrial Functional MR: An Analysis of the Global EXPAND Study

Moderated Poster Presenter: Nishtha Sodhi 9:34_AM Discussion 9:39_AM TCT 104: One Year Clinical Outcomes Following Open Transatrial

Transcatheter Mitral Valve Replacement in Patients With Severe Mitral Annular Calcification

Moderated Poster Presenter: Michael I. Brener 9:46_AM Discussion 9:51_AM TCT 105: Impact of pulmonary hypertension differentiation on the

outcome of patients undergoing MitraClip® therapy Moderated Poster Presenter: Tobias Schmidt

9:58_AM Discussion 10:03_AM TCT 106: Transcatheter Edge-To-Edge Mitral Valve Repair in Non-

COAPT Like Patients: Incidence and Predictors of 2-Year Good Outcome

Moderated Poster Presenter: Andrea Scotti 10:10_AM Discussion 10:15_AM TCT 107: Impact of Baseline Tricuspid Regurgitation Severity on

Clinical Outcomes After Transcatheter Edge-To-Edge Repair of the Mitral Valve With the MitraClipTM System



Moderated Poster Presenter: Jawad N. Chohan 10:22_AM Discussion

_

Tricuspid Valve Disease and Intervention

Structural: Valve _

Moderated Posters



11:00 AM - 12:00 PM

Tricuspid Valve Disease and Intervention Moderators: Basel Ramlawi, Jonathan G. Schwartz Discussants: João L. Cavalcante, Peter J J. Fitzgerald

11:00_AM TCT 138: Right Ventricular Remodeling and Clinical Outcomes Following Transcatheter Tricuspid Valve Intervention

Moderated Poster Presenter: Lyle Dershowitz 11:07_AM Discussion 11:12_AM TCT 139: Use of Steerable Guide Catheter to Improve Intracardiac

Ultrasound in Transcatheter Tricuspid Valve Edge to Edge Repair Moderated Poster Presenter: Patricio Alzamora

11:19_AM Discussion 11:24_AM TCT 140: A Novel Device For TR Reduction With A Feature Of ‘3D

Leaflet’ Hanging In The Center Of The Tricuspid Valve With An Atraumatic Anchoring Mechanism: The Pivot-TR System

Moderated Poster Presenter: Lee Seung-Whan 11:31_AM Discussion 11:36_AM TCT 141: In-Hospital Characteristics and Outcomes Among Patients

Treated with Off-Label Tricuspid Valve Transcatheter Edge to Edge Repair: An Analysis from The National In-Patient Sample 2016-2018

Moderated Poster Presenter: Nirat Beohar 11:43_AM Discussion 11:48_AM TCT 142: Clinical Outcomes Among Patients With Severe Tricuspid

Valve Regurgitation Moderated Poster Presenter: Vishal N. Rao


TVT Registry Studies

Structural: Valve _

Moderated Posters



12:00 PM - 1:00 PM

TVT Registry Studies Moderators: Toby Rogers, Ranya Sweis Discussants: Maria C. Alu, Wayne B. Batchelor, John D. Carroll

12:00_PM TCT 143: Transfemoral Versus Alternative Access for Transcatheter Aortic Valve Replacement With Evolut Platform

Moderated Poster Presenter: Michael Caskey 12:07_PM Discussion 12:12_PM TCT 144: Procedural and 30-day Outcomes of Patients Undergoing

TAVI-in TAVI: Insights from the TVT Registry Moderated Poster Presenter: Alan Zajarias

12:19_PM Discussion 12:24_PM TCT 145: Temporal Trends and Hospital Variation in Pacemaker

Implantation Following TAVR – Insights From the STS/ACC TVT Registry

Moderated Poster Presenter: Amit N. Vora 12:31_PM Discussion 12:36_PM TCT 146: Same Day Discharge After TAVR, TEER, TMVR, Watchman

Device Implantations: Call of the Pandemic or Expected Evolution? Moderated Poster Presenter: Mehul Patel

12:43_PM Discussion 12:48_PM TCT 147: Transcatheter Aortic Valve Replacement in Large Annuli

Valves with the Supra-Annular, Self-Expandable Evolut Platform: Insights From the STS/ACC TVT Registry

Moderated Poster Presenter: Luis Augusto Palma Dallan 12:55_PM Discussion

_

Plaque Modification

Coronary: CHIP _

Moderated Posters





1:00 PM - 2:00 PM

Plaque Modification Moderators: Issam D. Moussa Discussants: Lorenzo Azzalini, Neal S. Kleiman, Fayaz Shawl

1:00_PM TCT 119: Association Between Degree of Coronary Artery Calcification, Clinical Presentation, and Adverse Clinical Outcomes After PCI: A Patient-Level Pooled Analysis of Eleven Randomized Trials

Moderated Poster Presenter: Mahesh V. Madhavan 1:07_PM Discussion 1:12_PM TCT 120: Optical Coherence Tomography Characterization of

Shockwave Intravascular Lithotripsy for Treatment of Calcified Coronary Lesions: Patient-level Pooled Analysis of the Disrupt CAD OCT Sub-studies

Moderated Poster Presenter: Ziad A. Ali 1:19_PM Discussion 1:24_PM TCT 121: Intravascular Lithotripsy is Effective in the Treatment

Calcified Nodules: Patient-level Pooled Analysis From the Disrupt CAD OCT Sub-studies

Moderated Poster Presenter: Ziad A. Ali 1:31_PM Discussion 1:36_PM TCT 122: Sex-Specific Characteristics and Outcomes in Coronary

Intravascular Lithotripsy: A Patient-Level Analysis of the Disrupt CAD Studies

Moderated Poster Presenter: Yasin Hussain 1:43_PM Discussion 1:48_PM TCT 123: Evaluation of Pulsatile Intravascular Lithotripsy for

Controlled Fragmentation of Calcified Plaque in a Perfused Cadaver Model

Moderated Poster Presenter: Jon C. George 1:55_PM Discussion

_

Left Main and Bifurcation Disease and Intrervention

Coronary: CHIP _

Moderated Posters



2:30 PM - 3:18 PM

Left Main and Bifurcation Disease and Intrervention Moderators: Ricardo A. Costa, Miroslaw Ferenc Discussants: Salman Arain, Louis A. Cannon, Aaron V. Kaplan

2:30_PM TCT 97: Clinical Outcomes of Unprotected Left Main ST-Segment Elevation Myocardial Infarction

Moderated Poster Presenter: Aaqib H. Malik 2:37_PM Discussion 2:42_PM TCT 99: Clinical Outcomes in High Bleeding Risk Patients With

Bifurcations After Percutaneous Coronary Intervention With Resolute Onyx and One Month Dual Antiplatelet Therapy

Moderated Poster Presenter: Ajay J. Kirtane 2:49_PM Discussion 2:54_PM TCT 100: Real-World Experience and Outcomes of Protected versus

Unprotected Left Main Percutaneous Coronary Intervention: Insights from the VA CART Program

Moderated Poster Presenter: Yasin Hussain 3:01_PM Discussion 3:06_PM TCT 101: Long-term Outcomes Following Percutaneous Coronary

Intervention Versus Coronary Artery Bypass Grafting for Treating In-stent Restenosis in Unprotected Left Main Coronary Artery: Multicenter LM-DRAGON Registry

Moderated Poster Presenter: Wojciech Wojakowski 3:13_PM Discussion

_

Endovascular Diseases and Intervention

Endovascular _

Moderated Posters



3:30 PM - 4:30 PM

Endovascular Diseases and Intervention Moderators: William A. Gray Discussants: Anvar Babaev, Subhash Banerjee, James S. Eadie

3:30_PM TCT 73: Differential Risk Profiles and Presentation in Patients Hospitalized for Lower Extremity Peripheral Artery Disease by Ethnicity

Moderated Poster Presenter: Yulanka Castro 3:37_PM Discussion 3:42_PM TCT 74: Comparison of Standard Renal Denervation Procedure Versus

Novel Distal and Branch Vessel Ablation With Brachial Arterial Access Moderated Poster Presenter: Ivo Petrov

3:49_PM Discussion 3:54_PM TCT 75: Comparison of Large Bore Mechanical Thrombectomy and

Catheter Directed Thrombolysis in Patients With Acute Pulmonary Embolism: A Single Center Experience



Moderated Poster Presenter: Errol Inci 4:01_PM Discussion 4:06_PM TCT 76: Cardiology Cathlab-Based Management of Thrombotic

Carotid Stenoses in Acute Ischaemic Stroke en Route to a Full Interventional Stroke Service - Tools, Techniques, Local Stroke Unit Collaboration: Challenges and Patient Outcomes.

Moderated Poster Presenter: Piotr Musialek 4:13_PM Discussion 4:18_PM TCT 77: Temporal Trends, Practice Variation, and Associated

Outcomes With Use of Intravascular Ultrasound During Peripheral Arterial Intervention

Moderated Poster Presenter: Eric A. Secemsky 4:25_PM Discussion

_

Antiplatelet and Antithrombotic Drug Studies

Coronary: Core _

Moderated Posters



4:30 PM - 5:18 PM

Antiplatelet and Antithrombotic Drug Studies Moderators: Francesco Franchi, Sandeep Nathan Discussants: M Chadi Alraies, Vinay Kumar Bahl, Jennifer Rymer

4:30_PM TCT 35: One-Month Dual Antiplatelet Therapy After PCI With Resolute Onyx DES: Final 2-Year Results From Onyx One Clear

Moderated Poster Presenter: David E. Kandzari 4:37_PM Discussion 4:42_PM TCT 36: Double Versus Triple Antithrombotic Therapy After

Percutaneous Coronary Intervention: Contemporary Real-world Results From the WOEST2 Registry

Moderated Poster Presenter: Wilbert Bor 4:49_PM Discussion 4:54_PM TCT 38: Ticagrelor With and Without Aspirin in Patients With a Prior

Coronary Artery Bypass Graft Undergoing Percutaneous Coronary Intervention: The TWILIGHT-CABG Sub-Analysis.

Moderated Poster Presenter: Frans Joseph Beerkens 5:01_PM Discussion 5:06_PM TCT 39: Bleeding and Ischemic Outcomes With Ticagrelor

Monotherapy According to Body Mass Index: TWILIGHT-BMI Analysis

Moderated Poster Presenter: Carlo Andrea Pivato 5:13_PM Discussion

_

Endovascular Diseases and Intervention I

Endovascular _




8:00 AM - 9:00 AM

Endovascular Diseases and Intervention I Moderators: Danielle Bajakian, James S. Eadie Discussants: D. Christopher Metzger

8:00_AM TCT 551: Exploiting the Transformation Temperature to Reform an Infolded Nitinol Self-Expanding Peripheral Stent

Moderated Challenging Case Presenter: Giorgio A. Medranda 8:07_AM Discussion 8:12_AM TCT 552: Use of the Penumbra Lightning CAT-12 System in the

Evaluation of an Intracardiac Defibrillator Lead Mass Moderated Challenging Case Presenter: Ali Ebrahimi

8:19_AM Discussion 8:24_AM TCT 553: Exercise Induced Brachial Artery Pseudoaneurysm Treated

By Balloon Assisted Direct Human Thrombin Injection Moderated Challenging Case Presenter: Ramachandra Barik

8:31_AM Discussion 8:36_AM TCT 554: Percutaneous Endovascular Treatment of An Unusual Cause

Of Syncope Moderated Challenging Case Presenter: Justin Kenneth Ugwu

8:43_AM Discussion 8:48_AM TCT 556: Endovascular Treatment of Takayasu Arteritis in 13 y.o. Girl

Complicated With an Acute Occlusion of LCCA Moderated Challenging Case Presenter: Oksana Trebacz


Endovascular Diseases and Intervention II

Endovascular _






9:15 AM - 10:15 AM

Endovascular Diseases and Intervention II Moderators: William A. Gray, Jennifer Rymer Discussants: Anvar Babaev, Fayaz Shawl

9:15_AM TCT 558: Embolization of an Aneurysm in the Internal Iliac Artery, Followed by Correction of the Abdominal Aneurysm With the 'Aptus' System

Moderated Challenging Case Presenter: Jorge Luis Vivar Sanchez 9:22_AM Discussion 9:27_AM TCT 559: Venoplasty in Arteriovenous Fistula Dysfunction a

Palliative Endovascular Approach Moderated Challenging Case Presenter: Jeethender Kumar Kala

9:34_AM Discussion 9:39_AM TCT 560: Severe Mesenteric Ischemia in a Patient With Chronic

Lupus Vasculitis Treated Successfully by Endovascular Intervention Moderated Challenging Case Presenter: Aaron Brice

9:46_AM Discussion 9:51_AM TCT 561: A Multimodality Approach to IVC and Venous Thrombosis:

So Many Devices, So Little Data Moderated Challenging Case Presenter: Ashley Mohadjer

9:58_AM Discussion 10:03_AM TCT 562: Superficial Femoral Artery Aneurysm and Arteriovenous

Fistula Presenting as Critical Limb Ischemia Treated Successfully With Endovascular Repair

Moderated Challenging Case Presenter: Haitham Mazek 10:10_AM Discussion

_

Left Main and Bifurcation Intervention

Coronary: CHIP _




11:00 AM - 11:05 AM

Left Main and Bifurcation Intervention Moderators: Nicholas Joseph Lembo Discussants: Somjot S. Brar, Gennaro Giustino

_

CTO I

Coronary: CHIP _




12:00 PM - 12:48 PM

CTO I Moderators: Rhian E. Davies, Frederick Welt Discussants: Anja Oksnes, R. Michael Wyman

12:00_PM TCT 541: Complex Right Coronary Chronic Total Occlusion Solved With Intentional Trapliner Induced Dissection and Re-Entry

Moderated Challenging Case Presenter: Raj Chandwaney 12:07_PM Discussion 12:12_PM TCT 543: Image Guided Intervention for LMCA CTO in Takaysu

Arteritis Moderated Challenging Case Presenter: Pratap Kumar

12:19_PM Discussion 12:24_PM TCT 544: Retrograde CTO recannulization of mid LAD via Ipsilateral

Septal Collaterals using a Single Guiding Catheter Moderated Challenging Case Presenter: Ali Mahmood

12:31_PM Discussion 12:36_PM TCT 545: Utilizing Reverse Wire Technique to Solve Ostial LAD CTO

Moderated Challenging Case Presenter: Leah Raj 12:43_PM Discussion

_

CTO II

Coronary: CHIP _




1:00 PM - 1:48 PM

CTO II Moderators: Khaldoon F. Alaswad Discussants: Stefan Harb, Giora Weisz

1:00_PM TCT 546: Acute (re)occlusion, Techniques for Chronic Total Occlusion in an Acute Setting



Moderated Challenging Case Presenter: Judit Karacsonyi 1:07_PM Discussion 1:12_PM TCT 547: Flush Ostial RCA-CTO: When Retrograde Approach Is The

Only Option Moderated Challenging Case Presenter: Rami Abu Fanne

1:19_PM Discussion 1:24_PM TCT 548: Retrograde CTO PCI Rendezvous Technique

Moderated Challenging Case Presenter: Luis Areiza 1:31_PM Discussion 1:36_PM TCT 550: Power-Carlino, A Novel Method to Overcome Difficult-to-

Penetrate Proximal Cap Moderated Challenging Case Presenter: Michael Megaly


Unusual PCI Cases I

Coronary: Core _




2:30 PM - 3:06 PM

Unusual PCI Cases I Moderators: Gennaro Giustino Discussants: Hitinder Gurm

2:30_PM TCT 604: Hemoptysis From SVG Aneurysm Fistulization to Bronchial Tree Sealed With Covered Stent to Aneurysm Entrance

Moderated Challenging Case Presenter: Christopher Wasco 2:37_PM Discussion 2:42_PM TCT 606: Percutaneous Treatment of a Giant Saphenous Vein Graft

Aneurysm Moderated Challenging Case Presenter: Brandon Boyer

2:49_PM Discussion 2:54_PM TCT 607: Coronary Artery Tether Wiring

Moderated Challenging Case Presenter: Brittany Owen 3:01_PM Discussion

_

Unusual PCI Cases II

Coronary: CHIP Coronary: Core Structural: Non-Valve Structural: Valve _




3:30 PM - 4:30 PM

Unusual PCI Cases II Moderators: Morton J. Kern, Wojtek Wojakowski Discussants: Alfredo E. Rodriguez

3:30_PM TCT 609: Percutaneous Closure of a Large Diagonal Coronary Artery to Left Ventricular Fistula

Moderated Challenging Case Presenter: Jose Roberto Martinez-Parachini

3:37_PM Discussion 3:42_PM TCT 610: Intravascular Lithotripsy and Percutaneous Coronary

Intervention for Heavily Calcified Left Main Stenosis and Transcatheter Aortic Valve Replacement Under Upfront Extracorporeal Membrane Oxygenation Cardiopulmonary Support

Moderated Challenging Case Presenter: Hassan Harbi 3:49_PM Discussion 3:54_PM TCT 611: Look Before You Leap: Cardioplegia Mapping for Alcohol

Septal Ablation Moderated Challenging Case Presenter: Nicole Dexter

4:01_PM Discussion 4:06_PM TCT 612: Unprotected Left Main Disease and TAVR: What Do We Do

First? Moderated Challenging Case Presenter: Ronald Edgardo Rivas Gálvez

4:13_PM Discussion 4:18_PM TCT 613: A Unique Cause of Coronary Obstruction After Transcatheter

Aortic Valve Replacement Moderated Challenging Case Presenter: Chih-Wei Chang


Aortic and Tricuspid Valve Disease and Intervention

Structural: Valve _




4:30 PM - 5:18 PM

Aortic and Tricuspid Valve Disease and Intervention Moderators: Ori Ben-Yehuda, Nadira Hamid Discussants: Charles J. Davidson, Miroslaw Ferenc, Jonathan G. Schwartz

4:30_PM TCT 601: Percutaneous Repair for Primary Triscuspid Regugitation With Flail TV Leaflet

Moderated Challenging Case Presenter: Amer Alaiti 4:37_PM Discussion

TCT 2021 | SATURDAY, NOVEMBER 06, 2021


4:42_PM TCT 602: Percutaneous Atrial Septal Defect Closure in an Adult With Ebstein Anomaly as a Palliative Therapy for Recurrent Stroke

Moderated Challenging Case Presenter: Alex Cubberley 4:49_PM Discussion 4:54_PM TCT 581: Transcutaneous Edge-to-Edge Mitral Valve Repair With

Mitral Annular & Subvalvular Calcification Moderated Challenging Case Presenter: Adithya Mathews

5:01_PM Discussion 5:06_PM TCT 532: Kinked TAVR

Moderated Challenging Case Presenter: Sunny Goel 5:13_PM Discussion

_

Industry Hub

Industry Hub



8:00 AM - 5:30 PM

Industry Hub _


Virtual Exhibit



8:00 AM - 5:30 PM


SATURDAY, NOVEMBER 06, 2021 - _

Structural Heart Disease #9 - Cedars-Sinai Medical Center, Los Angeles, CA


Live Case Theater

SATURDAY, NOVEMBER 06, 2021 8:00 AM - 9:00 AM


8:00 AM - 9:00 AM

Structural Heart Disease #9 - Cedars-Sinai Medical Center, Los Angeles, CA Live Case Moderators: Vinod H. Thourani Live Case Co-Moderators: Torsten P. Vahl Live Case Discussants: David Daniels, Mark J. Russo, Molly Szerlip, Hendrik Treede Live Case Operators: Raj Makkar

8:00_AM Live Case Introduction for Structural Heart Disease #9 - Cedars-Sinai Medical Center, Los Angeles, CA

Moderator: Martin B. Leon 8:05_AM Structural Heart Disease #9 - Cedars-Sinai Medical Center, Los

Angeles, CA _

Coronary #9 - Abbott Northwestern, Minneapolis, MN


Live Case Theater



9:00 AM - 9:55 AM

Coronary #9 - Abbott Northwestern, Minneapolis, MN Live Case Moderators: Ajay J. Kirtane Live Case Co-Moderators: David J. Moliterno Live Case Discussants: Morton J. Kern Virtual Live Case Discussants: Rasha Al-Lamee, Sunil V. Rao, Georgios Sianos Live Case Operators: Emmanouil S. Brilakis, M. Nicholas M. Burke

_

Coronary #10 - Humanitas Medical Center, Milan, Italy, This live case is sponsored by CRF and supported through unrestricted educational grants from Alvimedica and Concept Medical.


Live Case Theater



10:00 AM - 11:00 AM

Coronary #10 - Humanitas Medical Center, Milan, Italy, This live case is sponsored by CRF and supported through unrestricted educational grants from Alvimedica and Concept Medical Live Case Moderators: Ran Kornowski Live Case Co-Moderators: Richard Shlofmitz Live Case Discussants: Alaide Chieffo, George D. Dangas, Yves R. Louvard, Luigi Salemme Live Case Operators: Antonio Colombo

10:00_AM Live Case Introduction of Coronary #10 - Humanitas Medical Center, Milan, Italy

Moderator: Antonio Colombo, Giora Weisz 10:02_AM Coronary #10 - Humanitas Medical Center, Milan, Italy 10:55_AM Conclusion



Moderator: Antonio Colombo _

Structural Heart Disease #10 - Abbott Northwestern, Minneapolis, MN


Live Case Theater

SATURDAY, NOVEMBER 06, 2021 11:00 AM - 12:00 PM


11:00 AM - 12:00 PM

Structural Heart Disease #10 - Abbott Northwestern, Minneapolis, MN Live Case Moderators: Michael J. Reardon Live Case Co-Moderators: Gilbert H. L. Tang Live Case Discussants: Christine Jee-Young Chung, Tsuyoshi Kaneko, Carlos E. Sanchez, Kimberly Skelding Live Case Operators: Vinayak N. Bapat, Paul Sorajja

11:00_AM Live Case Introduction for Structural Heart Disease #10 - Abbott Northwestern, Minneapolis, MN

Moderator: Vinayak N. Bapat, Martin B. Leon 11:02_AM Structural Heart Disease #10 - Abbott Northwestern, Minneapolis,

MN 11:56_AM Conclusion

Moderator: Vinayak N. Bapat, Martin B. Leon _

Award Presentation: Shark Tank

Live Case Theater

SATURDAY, NOVEMBER 06, 2021 1:00 PM - 1:15 PM


1:00 PM - 1:15 PM

Award Presentation: Shark Tank Award Presenter: Juan F. Granada, Grzegorz L. Kaluza, Robert S. Schwartz

1:00_PM Award Presentation Lecturer: Juan F. Granada

1:08_PM Shark Tank Winner Technology Presentation Lecturer: Unassigned1 Unassigned1

_

Hot Topic: PCI Bleeding Avoidance Strategies – Expert Case Management

Live Case Theater



1:15 PM - 2:45 PM

Hot Topic: PCI Bleeding Avoidance Strategies – Expert Case Management Moderators: Roxana Mehran, Gregg W. Stone Virtual Discussants: Tullio Palmerini, Sunil V. Rao, Kimberly Skelding

1:15_PM Pre-PCI Phase: Identifying the High Bleeding Risk Patient Virtual Lecturer: Roisin Colleran

1:25_PM PCI Phase: Bleeding Avoidance Strategies in the High Bleeding Risk Patient

Lecturer: Dominick J. Angiolillo 1:35_PM Roundtable Discussion

Guest Discussant: Dominick J. Angiolillo 1:45_PM Case #1 Introduction: A Patient With High Bleeding and High

Ischemic Risk Virtual Case Presenter: Davide Cao

1:48_PM Roundtable Discussion Guest Discussant: Davide Cao

1:57_PM Case #1 Resolution: A Patient With High Bleeding and High Ischemic Risk

Virtual Case Presenter: Davide Cao 2:00_PM Post-PCI Phase (Patient in NSR): Long-term Prevention of Bleeding

Virtual Lecturer: Davide Capodanno 2:10_PM Post-PCI Phase (Patient in AFib): Long-term Prevention of Bleeding

Virtual Lecturer: C. Michael Gibson 2:20_PM Roundtable Discussion

Guest Discussant: C. Michael Gibson 2:30_PM Case #2 Introduction: A Patient With Major Bleeding Post-PCI

Virtual Case Presenter: Kelly C. Epps 2:33_PM Roundtable Discussion 2:42_PM Case #2 Resolution: A Patient With Major Bleeding Post-PCI

Virtual Case Presenter: Kelly C. Epps _

Coronary #11 - University Heart Center, Bad Krozingen, Germany


Live Case Theater





2:45 PM - 3:45 PM

Coronary #11 - University Heart Center, Bad Krozingen, Germany Live Case Moderators: Gerald S. Werner Live Case Co-Moderators: Masahiko Ochiai Live Case Discussants: Chaim S. Lotan, Akiko Maehara, Tanveer Rab, Giora Weisz Live Case Operators: Mohamed Ayoub, Kambis Mashayekhi

2:45_PM Introduction of Live Case Coronary #11 - University Heart Center, Bad Krozingen, Germany

Moderator: Giora Weisz 2:50_PM Coronary #11 - University Heart Center, Bad Krozingen, Germany

_

Coronary #12 - University Heart Center, Bad Krozingen, Germany


Live Case Theater



3:45 PM - 4:45 PM

Coronary #12 - University Heart Center, Bad Krozingen, Germany Live Case Moderators: James C. Spratt Live Case Co-Moderators: Duane S. Pinto Live Case Discussants: Tullio Palmerini, Stephane Rinfret, David G. Rizik, Rajiv Tayal Live Case Operators: Mohamed Ayoub, Kambis Mashayekhi

3:45_PM Introduction of Live Case Coronary #12 - University Heart Center, Bad Krozingen, Germany

Moderator: Giora Weisz 3:50_PM Coronary #12 - University Heart Center, Bad Krozingen, Germany

_

Structural Heart Disease #11 - Cedars-Sinai Medical Center, Los Angeles, CA


Live Case Theater



4:45 PM - 5:45 PM

Structural Heart Disease #11 - Cedars-Sinai Medical Center, Los Angeles, CA Live Case Moderators: Samir R. Kapadia Live Case Co-Moderators: Juan F. Granada Live Case Discussants: Wayne B. Batchelor, Howard C. Herrmann, Anna Sannino, Firas Zahr Live Case Operators: Raj Makkar

4:45_PM Live Case Introduction for Structural Heart Disease #11 - Cedars-Sinai Medical Center, Los Angeles, CA

Moderator: Martin B. Leon 4:50_PM Structural Heart Disease #11 - Cedars-Sinai Medical Center, Los

Angeles, CA _

Structural Heart Disease #12 - Abbott Northwestern, Minneapolis, MN


Live Case Theater



5:45 PM - 6:40 PM

Structural Heart Disease #12 - Abbott Northwestern, Minneapolis, MN Live Case Moderators: Ramon Quesada Live Case Co-Moderators: Rebecca T. Hahn Virtual Live Case Discussants: David H. Adams, Paolo Denti, Maurizio Taramasso, Ralph Stephan von Bardeleben Live Case Operators: Vinayak N. Bapat, Paul Sorajja

_

CME Satellite: Latest in Transcatheter Repair Therapies for Mitral Regurgitation: TEER, Annuloplasty& Chordal Repair (Available in person and on demand only)

Satellites _



This session is not accredited. Discussants: Charles J. Davidson, Samir R. Kapadia, Scott Lima\nChairs: Mayra Guerrero, Susheel K. Kodalia\n

6:30 AM - 7:30 AM

Latest in Transcatheter Repair Therapies for Mitral Regurgitation: TEER, Annuloplasty& Chordal Repair Discussants: Megan Coylewright, Samir R. Kapadia, Konstantinos P. Koulogiannis, Scott Lim, Michael Joseph Rinaldi Chairs: Mayra Guerrero, Susheel K. Kodali



6:30_AM Welcome and Introductions Presenter: Mayra Guerrero, Susheel K. Kodali

6:31_AM TEER in “Yellow Light” zone: Insights from Global Experience Presenter: Megan Coylewright

6:41_AM Discussion 6:45_AM Transcatheter Annuloplasty - Can it Replicate Surgery

Presenter: Scott Lim 6:54_AM Indirect Annuloplasty Technology- Lessons Learned Over the Past

Decade Presenter: Samir R. Kapadia

7:01_AM Discussion 7:08_AM Early Outcomes with Beating Heart, Image-Guided Chordal Repair

Virtual Presenter: Konstantinos P. Koulogiannis 7:15_AM Transseptal Chordal Repair Technology - The Promise and The

Pitfalls Presenter: Michael Joseph Rinaldi

7:22_AM Discussion 7:26_AM Panel: What Will it Take to Make the Toolbox Approach a Reality? 7:30_AM Adjourn

_

Coronary Hot Topic #9: Case-Based Physiology Assessment and Procedural Guidance

Coronary: Core _




8:00 AM - 9:30 AM

Case-Based Physiology Assessment and Procedural Guidance Moderators: William F. Fearon, Allen Jeremias Discussants: Binita Shah Virtual Discussants: Claire E. Raphael, Habib Samady

8:00_AM Case-Based Learning: When to Use FFR vs NHPR and Are All NHPR the Same?

Virtual Lecturer: Jung-Min Ahn 8:08_AM Case-Based Learning: Managing Non-culprit Lesions in the STEMI

Patient With Coronary Physiology Lecturer: Pieter C. Smits

8:16_AM Case-Based Learning: Using Coronary Physiology to Guide CABG Virtual Lecturer: Emanuele Barbato

8:24_AM Roundtable Discussion 8:32_AM Case-Based Learning: Using Coronary Physiology to Guide

Revascularization in the Patient With Aortic Stenosis Virtual Lecturer: Christopher Cook

8:40_AM Case-Based Learning: Rationale and Techniques for Physiology Guided PCI – Distinguishing Focal From Diffuse Disease

Lecturer: Binita Shah 8:48_AM Case-Based Learning: Rationale and Techniques for Post-PCI

Coronary Physiology Assessment Virtual Lecturer: Damien Collison

8:56_AM Roundtable Discussion 9:04_AM Debate: It’s All About the Flow – Ischemia Predicts Events!

Lecturer: William F. Fearon 9:12_AM Debate: It’s All About the Plaque – Atherosclerotic Burden Is the

Most Important Predictor! Lecturer: Ziad A. Ali


Structural Hot Topic #9: Two Deep Dives – Mitral Imaging and Case Studies in Mitral Valve Disease, Part 1

Structural: Valve _




9:30 AM - 10:15 AM

Session I. Imaging Considerations in Transcatheter Mitral Valve Therapies



9:30_AM Classification and Quantification of Mitral Regurgitation Virtual Lecturer: Linda D. Gillam

9:37_AM Myths and Misperceptions of Proportionate vs Disproportionate MR

Virtual Lecturer: Paul A. Grayburn 9:44_AM Optimal Echo Techniques for MR Assessment: TTE or TEE? 2D or

3D? Virtual Lecturer: Konstantinos P. Koulogiannis

9:51_AM Structured CT Imaging Methods for Planning TMVR Virtual Lecturer: Jonathon A. Leipsic


Structural Hot Topic #9: Two Deep Dives – Mitral Imaging and Case Studies in Mitral Valve Disease, Part 2

Structural: Valve _




10:15 AM - 11:00 AM

Session II. Case Studies in Mitral Valve Disease Moderators: Anita W. Asgar, Megan Coylewright Discussants: Saibal Kar Virtual Discussants: Ralph Stephan von Bardeleben

10:15_AM Introduction Intro/ Closing Presenter: Anita W. Asgar

10:17_AM Case 1: Green Light – TMVr Based on Echo Imaging Virtual Case Presenter: Gnalini Sathananthan

10:21_AM Roundtable Discussion Guest Discussant: Gnalini Sathananthan

10:27_AM Case 2: Yellow Light TMVr – Case With Borderline MVOA and Prior Failed Surgical Annuloplasty

Case Presenter: Marc R. Katz 10:31_AM Roundtable Discussion

Discussant: Marc R. Katz 10:37_AM Case 3: Yellow Light TMVr – Barlow’s Valve With Multiple

Prolapsing Segments

Case Presenter: Vivian G. Ng 10:41_AM Roundtable Discussion

Discussant: Vivian G. Ng 10:47_AM Case 4: Red Light TMVr – MAC With MS/MR

Virtual Case Presenter: Leora Yarboro 10:51_AM Roundtable Discussion and Wrap-up

Discussant: Leora Yarboro 10:57_AM Closing Remarks & Adjourn

Intro/ Closing Presenter: Anita W. Asgar _

Late-Breaking Clinical Trials Session III, In Collaboration With JACC





11:00 AM - 12:00 PM

Late-Breaking Clinical Trials Session III, In Collaboration With JACC Co-Moderators: David J. Moliterno Virtual Moderators: Valentin Fuster Discussants: Stephen G. Ellis, Dhanunjaya Lakkireddy Virtual Discussants: Robert A. Byrne, Shephal Doshi, Anu Lala-Trindade, Clyde W. Yancy

11:00_AM SWISS-APERO: A Randomized Trial of the Amulet Versus Watchman FLX Devices for Left Atrial Appendage Closure

Presenter: Roberto Galea 11:12_AM Discussion

Guest Discussant: Roberto Galea 11:20_AM OPT-PEACE: A Double-blind Randomized Trial of the Effect of

Different Antiplatelet Regimens on Gastrointestinal Injury Virtual Presenter: Yaling Han

11:32_AM Discussion Guest Discussant: Yaling Han



11:40_AM GUIDE-HF: A Randomized Trial of Hemodynamic-Guided Management of Heart Failure – Outcomes According to Ejection Fraction

Virtual Presenter: Michael R. Zile 11:52_AM Discussion

Guest Discussant: JoAnn Lindenfeld _

Late-Breaking Clinical Science Session III





1:00 PM - 2:00 PM

Late-Breaking Clinical Science Session III Co-Moderators: Juan F. Granada Virtual Moderators: Fernando Alfonso Discussants: Anita W. Asgar, Wayne B. Batchelor, Steven F. Bolling Virtual Discussants: João L. Cavalcante, Marc Gillinov, Maurizio Taramasso

1:00_PM A Randomized Trial of Sirolimus-coated Versus Paclitaxel-coated Balloons in De Novo Coronary Lesions

Virtual Presenter: Wan Azman Wan Ahmad 1:08_PM BIO-RISE CHINA: A Randomized Trial of a Biolimus-Coated Balloon

Versus POBA in Small Vessel Coronary Artery Disease Virtual Presenter: Yaling Han

1:16_PM One-year Outcomes of Two Parallel Randomized Trials of Sirolimus-Coated and Paclitaxel-Coated Balloons in Coronary In-Stent Restenosis Lesions

Presenter: Bruno Scheller 1:24_PM Discussion 1:34_PM Intrepid TMVR Early Feasibility: Thirty-Day Outcomes Following

Transfemoral Transseptal Transcatheter Mitral Valve Replacement Presenter: Firas Zahr

1:42_PM Discussion

1:47_PM TRISCEND: Six-Month Outcomes of Transfemoral Tricuspid Valve Replacement in Patients With Tricuspid Regurgitation

Presenter: Susheel K. Kodali 1:55_PM Discussion

_

Structural Hot Topic #10: TAVR Hot Topic – Valve Hemodynamics and PPM Assessment

Structural: Valve _




2:00 PM - 3:00 PM

TAVR Hot Topic: Valve Hemodynamics and PPM Assessment Moderators: Amr E. Abbas, Rebecca T. Hahn Discussants: Itsik Ben-Dor Virtual Discussants: Jeroen J. Bax, Julien Ternacle

2:00_PM What Is the Definition and Clinical Impact of Prosthesis-Patient Mismatch in TAVR

Virtual Lecturer: Philippe Pibarot 2:08_PM Roundtable Discussion

Guest Discussant: Philippe Pibarot 2:12_PM Echo vs Cath Discordance in the Measurement of Transvalvular

Pressure Gradients Lecturer: Amr E. Abbas

2:20_PM Roundtable Discussion Discussant: Amr E. Abbas

2:24_PM Special Considerations of Valve Hemodynamics and Prosthesis-Patient Mismatch in the Small Annulus

Virtual Lecturer: Howard C. Herrmann 2:32_PM Roundtable Discussion

Guest Discussant: Howard C. Herrmann 2:36_PM Special Considerations of Valve Hemodynamics and Prosthesis-

Patient Mismatch Following Valve-in-Valve Virtual Lecturer: Janarthanan Sathananthan



2:44_PM Roundtable Discussion Guest Discussant: Janarthanan Sathananthan

2:48_PM Prosthetic Valve Selection and Implant Techniques for Prevention of PPM/High Residual Gradients Following SAVR, TAVR, or Valve-in-Valve

Lecturer: David A. Wood 2:56_PM Roundtable Discussion and Wrap-up

Discussant: David A. Wood _

Structural Hot Topic #11: Left Atrial Appendage Closure, Part 1





3:00 PM - 3:45 PM

Session I. Key Controversies in Transcatheter LAA closure Moderators: Saibal Kar, Matthew J. Price Discussants: Elliott Michael Groves, Vivian G. Ng, Jacqueline Saw Virtual Discussants: Vivek Y. Reddy

3:00_PM Optimal Pharmacotherapy Post-LAAC 3:00_PM Antiplatelet Therapy Is Sufficient for DRT

Prevention After LAAC Lecturer: Jacqueline Saw

3:05_PM Oral Anticoagulation Should Be the Default Strategy After LAAC

Lecturer: Matthew J. Price


3:15_PM Can LAAC Be Just Another Case in the Cath Lab Without an Anesthesiologist and Imager?

3:15_PM ICE Imaging Should Be the Default Approach to LAAC Procedural Imaging

Lecturer: Mohamad Alkhouli

3:20_PM ICE Imaging Is Not Ready for Prime-Time: TEE Should Be the Default Approach

Lecturer: Brijeshwar Maini


3:29_PM NOACs vs LAAO for Stroke Prevention in AF Patients Who Are Indicated for OAC

3:29_PM LAAO or NOACs for Stroke Prevention in Most AF Patients: Clinical Trials Are Necessary

Virtual Lecturer: Vivek Y. Reddy

3:35_PM Equipoise Is a Myth: NOACs Will Be Superior to LAAO

Virtual Lecturer: Renato D. Lopes

3:40_PM Roundtable Discussion and Wrap-up

_

Structural Hot Topic #11: Left Atrial Appendage Closure, Part 2





3:45 PM - 4:30 PM

Session II. Left Atrial Appendage Closure: Procedural Advances and New Devices Moderators: Mohamad Alkhouli, Dee Dee Wang Discussants: Krzysztof Bartus Virtual Discussants: Bushra S. Rana, Lars Sondergaard

3:45_PM Introduction Intro/ Closing Presenter: Mohamad Alkhouli, Dee Dee Wang

3:47_PM A Case Where I Was Really Happy to Have Pre-Procedural CT Planning as Additive Planning for Intraprocedural TEE

Case Presenter: Dee Dee Wang 3:51_PM Roundtable Discussion

Discussant: Dee Dee Wang 3:55_PM A Case Where I Was Really Happy to Have Intraprocedural ICE When

TEE Was Not First Line Virtual Case Presenter: Shephal Doshi



3:59_PM Roundtable Discussion Virtual Discussant: Shephal Doshi

4:02_PM Patient Anatomical Selection for LAAO: Should There Be Imaging Consensus Anatomical Criteria?

Lecturer: Dee Dee Wang 4:06_PM Roundtable Discussion

Discussant: Dee Dee Wang 4:10_PM Closing Complex Anatomies LAAO Devices

Lecturer: Brian K. Whisenant 4:14_PM Roundtable Discussion

Discussant: Brian K. Whisenant 4:18_PM LAAO in 2030: My 5 Top Predictions for the Field

Virtual Lecturer: David R. Holmes Jr. 4:24_PM Roundtable Discussion

Guest Discussant: David R. Holmes Jr. 4:28_PM Closing Thoughts & Adjourn

Intro/ Closing Presenter: Mohamad Alkhouli, Dee Dee Wang _

Coronary Hot Topic #12: Intravascular Imaging Using IVUS and OCT – A Case-Based Direct Comparison

Coronary: Core _




4:30 PM - 6:00 PM

Intravascular Imaging Using IVUS and OCT : A Case-Based Direct Comparison Moderators: Ziad A. Ali, Gary S. Mintz Discussants: Zachary George, Akiko Maehara Virtual Discussants: Claudia Cosgrove

4:30_PM Case 1: IVUS vs OCT Using the MLD-MAX Algorithm for PCI-Guidance – Direct Comparison

Case Presenter: Evan Shlofmitz 4:38_PM Roundtable Discussion

Discussant: Evan Shlofmitz 4:45_PM Case 2: Removing Ambiguity in NSTE-ACS Using Intravascular

Imaging by OCT vs IVUS – Direct Comparison

Case Presenter: Natalia Pinilla-Echeverri 4:53_PM Roundtable Discussion

Discussant: Natalia Pinilla-Echeverri 5:00_PM Case 3: Mechanism and Management of In-stent Restenosis by OCT

vs IVUS – Direct Comparison Virtual Case Presenter: Do-Yoon Kang

5:08_PM Roundtable Discussion Guest Discussant: Do-Yoon Kang

5:15_PM Case 4: OCT vs IVUS-Guided Management of Coronary Calcification – Direct Comparison

Virtual Case Presenter: Duk-Woo Park 5:23_PM Roundtable Discussion

Guest Discussant: Duk-Woo Park 5:30_PM Case 5: Left Main Bifurcation by IVUS vs OCT – Direct Comparison

Virtual Case Presenter: Daniel Chamie 5:38_PM Roundtable Discussion

Guest Discussant: Daniel Chamie 5:45_PM Case 6: Multi-Modality Imaging and Physiology to Diagnose Angina

Without Angiographic Stenosis Virtual Case Presenter: Jennifer A. Tremmel

5:53_PM Roundtable Discussion and Wrap-up Guest Discussant: Jennifer A. Tremmel

_

Structural Hot Topic #12: PFO Closure – Concepts and Controversies





6:00 PM - 7:00 PM

PFO Closure: Concepts and Controversies Moderators: Megan Coylewright, Robert J. Sommer Virtual Discussants: David William Dodick, David Hildick-Smith, John M. Lasala, John F. Rhodes



6:00_PM Technical Workshop on PFO Closure: Managing Challenging Anatomy – My Way Case-Based Presentations

6:00_PM Aneurysmal Septum Primum Virtual Case Presenter: John M. Lasala

6:04_PM Long, Rigid Tunnels Case Presenter: Megan Coylewright

6:08_PM Multi-Fenestrated Septum Primum Virtual Case Presenter: David Hildick-Smith

6:12_PM Femoral Venous Pathway Obstruction: Alternate Vascular Approaches

Virtual Case Presenter: John F. Rhodes

6:16_PM When Bad Things Happen to Good People: Avoiding and Managing PFO Complications

Lecturer: Carey D. Kimmelstiel 6:22_PM Roundtable Discussion 6:30_PM Featured Hot Topic: A Platelet-Mediated Mechanism for PFO and

Migraine Headache- Update on RELIEF Virtual Lecturer: David William Dodick

6:36_PM Roundtable Discussion 6:40_PM PFO Controversies: Data-Free Zones

6:40_PM Should All PFOs Be Closed After an Ischemic Stroke?

Virtual Discussant: Steven R. Messe

6:44_PM Should PFO Anatomic Features Influence Clinical Decision-making?

Virtual Discussant: Howard C. Herrmann

6:48_PM Should PFO Closure Be Considered in Patients Outside the Age Groups Included in the RCTs?

Discussant: Carey D. Kimmelstiel

6:52_PM Does the Choice and Duration of Post-PFO Implant Antithrombotic Therapy Matter?

Virtual Discussant: David Hildick-Smith

6:56_PM Post-PFO Closure Atrial Fibrillation: What Is the Real Incidence and Is It Clinically Important?

Discussant: Robert J. Sommer

_

Satellite: Transforming Hypertension Treatment: From Evidence to Consensus to Action

Satellites _

Innovation Theater



6:30 AM - 7:30 AM

Transforming Hypertension Treatment: From Evidence to Consensus to Action

6:30_AM Introduction & Objectives Satellite Presenter: Raymond R. Townsend

6:35_AM Leading with Evidence: Latest Data on Renal Denervation Satellite Presenter: Raymond R. Townsend

6:45_AM Leading with Evidence: US Patient Preference Virtual Satellite Presenter: Atul Pathak

6:55_AM Establishing Consensus: European Guidance Updates Virtual Satellite Presenter: Konstantinos P. Tsioufis

7:05_AM Establishing Consensus: US Guidance Updates Satellite Presenter: Eric A. Secemsky

7:15_AM Who is right for RDN? Virtual Satellite Presenter: Joachim Weil

7:25_AM Key Learnings & Conclusions Satellite Presenter: Raymond R. Townsend

_

Coronary Hot Topic #10: SCAD, MINOCA, INOCA, Takotsubo Syndrome

Coronary: Core _

Innovation Theater



8:00 AM - 9:00 AM

SCAD, MINOCA, INOCA, Takotsubo Syndrome



8:00_AM Introduction Intro/ Closing Presenter: Jacqueline Saw

8:02_AM Case-Based Presentation 1: SCAD – When to Intervene and When Not to Intervene

Virtual Case Presenter: Sarah Zaman 8:09_AM Roundtable Discussion

Guest Discussant: Sarah Zaman 8:14_AM Case-Based Presentation 2: MINOCA – Common Things Are

Common (Plaque Rupture, Erosion) Virtual Case Presenter: Harmony Reynolds

8:21_AM Roundtable Discussion 8:25_AM Case-Based Presentation 3: Takotsubo Syndrome – Update and

Impact of COVID on TTS Virtual Case Presenter: Salvatore Brugaletta

8:32_AM Roundtable Discussion Guest Discussant: Salvatore Brugaletta

8:36_AM Case-Based Presentation 4: INOCA – How to Diagnose and Treat Coronary Spasm

Case Presenter: Bruce Samuels 8:43_AM Roundtable Discussion

Guest Discussant: Bruce Samuels 8:47_AM Case-Based Presentation 5: INOCA – How to Diagnose and Treat

Coronary Microvascular Dysfunction (CMD) Virtual Case Presenter: Colin Berry

8:54_AM Roundtable Discussion Guest Discussant: Colin Berry

8:58_AM Take-home Messages Intro/ Closing Presenter: Mamas Mamas

_

Coronary Hot Topic #11: New Directions: From ISCHEMIA to Vulnerable Plaque

Coronary: CHIP _

Innovation Theater



9:00 AM - 10:00 AM

New Directions: From ISCHEMIA to Vulnerable Plaque Moderators: Akiko Maehara, Ron S. Waksman Virtual Discussants: David Erlinge, Bon-Kwon Koo, James E. Muller

9:00_AM Case Presentation 1 Case: Vulnerable Stenosis by CTA, but FFR Negative or Borderline (From Dr. Koo); Vulnerable Stenosis by OCT/IVUS/NIRS/s Ischemia (From Dr. Erlinge)

Virtual Case Presenter: Jeehoon Kang 9:05_AM Beyond ISCHEMIA: Role of CT Angiography for Plaque Extent and

Morphology Virtual Lecturer: Jagat Narula

9:13_AM Local Hemodynamics for Plaque Vulnerability Virtual Lecturer: Shengxian Tu

9:21_AM What Plaque Characteristics Cause Future Events: Plaque Burden, Lipid, Ischemia, or Other?

Virtual Lecturer: David Erlinge 9:29_AM Vulnerable Plaques Detected With OCT Adds to Physiology

Virtual Lecturer: Colin Berry 9:37_AM Is It Prime Time to Treat Vulnerable Plaque?

Lecturer: Gregg W. Stone 9:45_AM Roundtable Discussion and Wrap-Up

_

Interventional Heart Failure 1: Overview

Innovation Theater



10:00 AM - 11:00 AM

Overview Moderators: Daniel Burkhoff, Jerry D. Estep Discussants: Marat Fudim Virtual Discussants: Javed Butler, Anu Lala-Trindade, Milton Packer



10:00_AM Overview of Devices for HF: Current and Future Prospects Lecturer: Marat Fudim

10:05_AM LV Reconstruction I: Ancora Lecturer: Nadira Hamid

10:11_AM LV Reconstruction II: Bioventrix Lecturer: Gregg W. Stone

10:17_AM Interatrial Shunts: Physiological Rationale and Hemodynamic Effects

Lecturer: Daniel Burkhoff 10:24_AM Neuromodulation for Heart Failure

10:24_AM CVRx - Barostimulation -- CVRx and LivaNova

Virtual Lecturer: Michael R. Zile

10:30_AM Impulse Dynamics - CCM Virtual Lecturer: Javed Butler

10:36_AM **CONVERT TO DISCUSSION** AXON Therapeutics

Virtual Lecturer: Sanjiv Shah

10:42_AM Roundtable Discussion With Audience Q&A _

Interventional Heart Failure 2: Acute Decompensated Heart Failure

Innovation Theater



11:00 AM - 12:00 PM

Interventional Heart Failure 2: Acute Decompensated Heart Failure Moderators: Daniel Burkhoff, James E. Udelson Discussants: Daniel R. Bensimhon Virtual Discussants: Manreet Kanwar, Navin K. Kapur, Sean P. Pinney

11:00_AM ADHF Pathophysiology and Emerging Devices (DRIIPPS) Virtual Lecturer: W. H. Wilson Tang

11:08_AM Manipulation of Renal Preload and Afterload for Acute Decompensated Heart Failure

Virtual Lecturer: Navin K. Kapur 11:15_AM New Approaches to Diuresis - Reprieve

Virtual Lecturer: Jeffrey Testani 11:23_AM Treating the Lymphatic System for Acute and Chronic HF

Lecturer: Marat Fudim 11:31_AM AquaPass

Lecturer: Doron Aronson 11:38_AM FUROSCIX CRLs (scPharmaceuticals)

Lecturer: Daniel R. Bensimhon 11:46_AM Roundtable Discussion With Audience Q&A

_

Interventional Heart Failure 3: Patient Monitoring

Innovation Theater



1:00 PM - 2:00 PM

Interventional Heart Failure 3: Patient Monitoring Moderators: Marat Fudim, JoAnn Lindenfeld Discussants: Daniel R. Bensimhon, Daniel Burkhoff Virtual Discussants: Donna Mancini

1:00_PM PA Pressure Monitoring: Leasons Learned From CHAMPION and GUIDE-HF

Lecturer: JoAnn Lindenfeld 1:12_PM Can Multi-Parameter Noninvasive Systems be as Effective as

Invasive PA Pressure? Virtual Lecturer: John P. Boehmer

1:20_PM Newer Invasive Pressure Monitoring Devices Lecturer: Liviu Klein

1:28_PM Use of Transthoracic Radar Monitoring for Assessing Volume Status (Sensible Medical)

Lecturer: Daniel R. Bensimhon 1:34_PM Inferior Vena Caval Size Monitoring

Virtual Lecturer: Jeffrey Testani 1:40_PM Changes in Voice Patterns for Monitoring Volume Status (Cardio)

Virtual Lecturer: Chaim S. Lotan 1:46_PM Roundtable Discussion With Audience Q&A



_

Endovascular Featured Clinical Research

Endovascular _

Innovation Theater



2:00 PM - 3:00 PM

Endovascular Featured Clinical Research Co-Moderators: Robert A. Lookstein, Sahil A. Parikh Discussants: Subhash Banerjee, Peter J J. Fitzgerald, Tilo Kölbel Virtual Discussants: Marc P. Bonaca, Marianne Brodmann, Douglas E. Drachman

2:00_PM Acute and Long-term Improvements Following FlowTriever Mechanical Thrombectomy in Pulmonary Embolism Patients: Six-Month Results From the FLASH Registry

Presenter: Catalin Toma 2:08_PM Discussion

Guest Discussant: Catalin Toma 2:12_PM Determinants of Drug-coated Balloon Failure in Femoropopliteal

Intervention. Insights From a Patient-level Pooled Analysis Lecturer: Prakash Krishnan

2:20_PM Discussion Guest Discussant: Prakash Krishnan

2:24_PM Utilization of Intravascular Ultrasound During Peripheral Venous Intervention Among Medicare Beneficiaries

Presenter: Eric A. Secemsky 2:32_PM Discussion

Guest Discussant: Eric A. Secemsky 2:36_PM Directional Versus Orbital Atherectomy of Femoropopliteal Artery

Lesions: Angiographic and Intravascular Ultrasound Outcomes Presenter: Anvar Babaev

2:44_PM Discussion Guest Discussant: Anvar Babaev

2:48_PM Hybrid Drug Eluting Scaffold for Large Vessel Arterial Drug Delivery Presenter: Sahil A. Parikh

2:56_PM Discussion Guest Discussant: Sahil A. Parikh

_

Endovascular: Lower Extremity PAD State-of-the-art

Endovascular _

Innovation Theater



3:00 PM - 4:00 PM

Lower Extremity PAD State-of-the-art Moderators: D. Christopher Metzger, Sahil A. Parikh Discussants: Lawrence A. Garcia, Prakash Krishnan, Peter A. Soukas Virtual Discussants: Marianne Brodmann

3:00_PM Medical Therapy for PAD: PCSK9, SGLT2, Anticoagulation and Beyond

Virtual Lecturer: Connie N. Hess 3:08_PM Have We Gotten to the Final Word on Paclitaxel Safety?

Lecturer: Eric A. Secemsky 3:16_PM Discussion: SFA Treatment Algorithm 3:20_PM Case Presentation: Long Segment SFA Occlusion

Case Presenter: Mohammad Mehdi Ansari 3:24_PM Role of Drug Eluting Technologies as Definitive Therapy

Virtual Lecturer: Thomas Zeller 3:32_PM Atherectomy as an Adjunct to Long-term Patency

Lecturer: Ravish Sachar 3:40_PM Scaffolds are Back - What's Old is New

Lecturer: Sahil A. Parikh 3:48_PM Discussion: SFA Treatment Algorithm 3:52_PM Opportunities to Improve Outcomes: IVUS

Lecturer: Eric A. Secemsky _

Endovascular: CLI

Endovascular _

Innovation Theater





4:00 PM - 5:00 PM

CLI Moderators: Robert A. Lookstein, Kenneth Rosenfield Discussants: Danielle Bajakian Virtual Discussants: Robert Earl Beasley, Jun Li, Peter A. Schneider

4:00_PM New Data on Racial Disparities Virtual Lecturer: Foluso Fakorede

4:07_PM Discussion 4:10_PM New Tech for CLI: Scaffolds

Virtual Lecturer: Brian G. DeRubertis 4:17_PM New Tech for CLI: Atherectomy

Virtual Lecturer: Peter P. Monteleone 4:24_PM New Tech for CLI: Distal Access

Virtual Lecturer: Arthur C. Lee 4:31_PM New Tech for CLI: DVA

Virtual Lecturer: Mehdi H. Shishehbor 4:38_PM Discussion 4:45_PM Drug Elution Challenges and Opportunities

Lecturer: Wojtek Wojakowski 4:53_PM Discussion: Below the Knee Drug Elution: Will it Ever Work?

_

Endovascular: Pulmonary Embolism – Controversies and Crossroads

Endovascular _

Innovation Theater



5:00 PM - 6:00 PM

Pulmonary Embolism – Controversies and Crossroads Moderators: Jay S. Giri, Robert A. Lookstein Discussants: Vikas Aggarwal, Teresa L. Carman, Kenneth Rosenfield, Sanjum S. Sethi

5:00_PM Clinical Trials Paving the Way for Data Lecturer: Robert A. Lookstein

5:08_PM Discussion 5:10_PM Massive PE Case

Virtual Case Presenter: Matthew T. Finn 5:15_PM The Role of MCS Assisted With Catheter Directed Therapy

Lecturer: Sanjum S. Sethi 5:23_PM The Role of Open Embolectomy

Virtual Lecturer: Brent Keeling 5:31_PM CDT: EKOS and Beyond

Virtual Lecturer: Gregory Piazza 5:38_PM Thrombectomy: Inari, Penumbra, and Angiovac

Lecturer: Kenneth Rosenfield 5:45_PM What About Anticoagulation Alone?

Lecturer: Teresa L. Carman 5:52_PM Discussion

_

Featured Clinical Research Session III

Innovation Theater





6:00 PM - 7:00 PM

TCT 2021 Featured Clinical Research Session III Moderators: Stephen G. Ellis, Martin B. Leon Discussants: Daniel Burkhoff, Nadira Hamid Virtual Discussants: Kenneth Chin, Runlin Gao, Stefan K. James, Adnan Kastrati, Yoshinobu Onuma

6:00_PM BIO-RESORT: Five-Year Outcomes from a Randomized Trial of Three Drug-Eluting Stents in Patients With Coronary Artery Disease

Virtual Presenter: Eline Ploumen 6:08_PM Discussion

Guest Discussant: Eline Ploumen 6:12_PM BIODEGRADE: Three-Year Outcomes From a Randomized Trial of

Biolimus-eluting Versus Zotarolimus-eluting Stents in Patients With Coronary Artery Disease

Presenter: IN-HO CHAE 6:20_PM Discussion

Guest Discussant: IN-HO CHAE 6:24_PM TIDES-ACS: Three-Year Outcomes From a Randomized Trial of

Titanium Nitride Oxide-Coated Versus Everolimus-eluting Stents in Patients With Acute Coronary Syndromes

Virtual Presenter: Pasi Karjalainen 6:32_PM Discussion 6:36_PM AccuCinch: Outcomes of Transcatheter LV Volume Reduction in HFrEF

With a Transcatheter Ventricular Restoration System Virtual Presenter: Ulrich P. Jorde

6:44_PM Discussion Guest Discussant: Ulrich P. Jorde

6:48_PM EXPAND G4: Core Laboratory Echocardiographic Outcomes From a Multicenter Study of a Fourth Generation TEER System to Treat Mitral Regurgitation

Presenter: Evelio Rodriguez 6:56_PM Discussion

Guest Discussant: Evelio Rodriguez _

Satellite: The Conundrum of Managing Chronic Coronary Disease: DPI or DAPT?

Satellites _




9:00 AM - 10:00 AM

The Conundrum of Managing Chronic Coronary Disease: DPI or DAPT?

9:00_AM Understanding the Options: DAPT or DPI in Patients with Chronic Coronary Disease

Virtual Presenter: Deepak L. Bhatt 9:10_AM Disease State and Comorbidities: How Specific Clinical Issues Drive

Therapeutic Decision-making in Patients with Chronic Coronary Disease

Virtual Presenter: Marc P. Bonaca 9:20_AM Go With the Flow? Differential Rheology in the Coronary and

Peripheral Vascular Beds Virtual Presenter: Paul Gurbel

9:30_AM Case Studies and Faculty Discussion: Making the “Right” Decision in the Absence of Head-to-Head Trial

Virtual Discussant: Deepak L. Bhatt, Marc P. Bonaca, Paul Gurbel 9:45_AM Faculty Panel Discussion

Virtual Discussant: Deepak L. Bhatt, Marc P. Bonaca, Paul Gurbel _

Satellite: Sirolimus Coated Balloon: What the FUTURE holds for PAD

Satellites _




10:00 AM - 11:00 AM

Sirolimus Coated Balloon: What the FUTURE holds for PAD



10:00_AM Session Objectives & Opening Remarks Satellite Presenter: Sahil A. Parikh

10:01_AM The potential of Sirolimus Coated Balloon as a better option for PAD Intervention

Moderators: Sahil A. ParikhVirtual Satellite Presenters: Aloke Finn 10:08_AM Discussion

Moderators: Sahil A. ParikhVirtual Discussants: Stefano Barco, Edward Choke, Aloke Finn, Ulf Teichgräber

10:13_AM 1-year results of XTOSI trial with case reviews and updates on the FUTURE BTK and SFA RCT

Moderators: Sahil A. ParikhVirtual Satellite Presenters: Edward Choke

10:25_AM Discussion Moderators: Sahil A. ParikhVirtual Discussants: Stefano Barco,

Edward Choke, Aloke Finn, Ulf Teichgräber 10:30_AM SIRONA – Head to Head comparison of Sirolimus Vs Paclitaxel Drug

Eluting Balloon for Femoral Popliteal Artery Moderators: Sahil A. ParikhVirtual Satellite Presenters: Ulf

Teichgräber 10:40_AM Discussion


10:45_AM SirPAD - The largest Randomised trial with a Sirolimus Coated Balloon for Peripheral Arterial Disease Treatment

Moderators: Sahil A. ParikhVirtual Satellite Presenters: Stefano Barco 10:52_AM Discussion & Conclusion


_

Satellite: Master The Complex

Satellites _




11:00 AM - 12:00 PM

Master The Complex

11:00_AM IVUS Guided PCI for Calcified lesions Moderators: Rafael CavalcanteVirtual Discussants: Dhiman Kahali,

Pratap Kumar, Ajit R. Menon, balbir singhSatellite Presenters: Ajay J. Kirtane

11:10_AM Algorithmic Approach to Plaque Modification: My Experience Moderators: Rafael CavalcanteDiscussants: Ajay J. KirtaneVirtual

Discussants: Dhiman Kahali, Pratap Kumar, balbir singhVirtual Satellite Presenters: Ajit R. Menon

11:20_AM Zero Contrast IVUS Guided PCI: A New Reality Moderators: Rafael CavalcanteDiscussants: Ajay J. KirtaneVirtual

Discussants: Dhiman Kahali, Ajit R. Menon, balbir singhVirtual Satellite Presenters: Pratap Kumar

11:30_AM Strategies for Successful LM Bifurcation PCI Moderators: Rafael CavalcanteDiscussants: Ajay J. KirtaneVirtual

Discussants: Dhiman Kahali, Pratap Kumar, Ajit R. MenonVirtual Satellite Presenters: balbir singh

11:40_AM Latest Evidence on Short DAPT & HBR Patients Discussants: Ajay J. KirtaneVirtual Discussants: Dhiman Kahali,

Pratap Kumar, Ajit R. Menon, balbir singhSatellite Presenters: Rafael Cavalcante

11:50_AM Round Table Discussion & Wrap Up Moderators: Rafael CavalcanteDiscussants: Ajay J. KirtaneVirtual

Discussants: Dhiman Kahali, Pratap Kumar, Ajit R. Menon, balbir singh

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Satellite: Smith Center Symposium on Intravascular Ultrasound for Lower Extremity Arterial and Venous Intervention

Satellites _




1:00 PM - 2:00 PM

Smith Center Symposium on Intravascular Ultrasound for Lower Extremity Arterial and Venous Intervention

1:00_PM IVUS Arterial Overview and Systematic Review Satellite Presenter: Sahil A. Parikh

1:08_PM How I Use IVUS during Arterial Intervention Satellite Presenter: D. Christopher Metzger

1:16_PM Moderated Discussion Discussant: Danielle Bajakian, Robert A. Lookstein, Santhosh Jay

Mathews, D. Christopher Metzger, Sahil A. Parikh, Eric A. Secemsky 1:25_PM IVUS Venous Overview and Systematic Review

Satellite Presenter: Santhosh Jay Mathews 1:33_PM How I Use IVUS during Venous Intervention



Satellite Presenter: Robert A. Lookstein 1:41_PM Moderated Discussion

Discussant: Danielle Bajakian, Robert A. Lookstein, Santhosh Jay Mathews, D. Christopher Metzger, Sahil A. Parikh, Eric A. Secemsky

1:52_PM IVUS Consensus Document Results Satellite Presenter: Eric A. Secemsky

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Satellite: Advancing the Treatment of Uncontrolled Hypertension with Ultrasound RDN

Satellites _




2:00 PM - 3:00 PM

Advancing the Treatment of Uncontrolled Hypertension with Ultrasound RDN

2:00_PM Welcome Moderator: Ajay J. Kirtane

2:02_PM Get To Know Ultrasound RDN (uRDN) Virtual Satellite Presenter: Chandan Devireddy

2:12_PM Update On The Latest Clinical Evidence Satellite Presenter: Ajay J. Kirtane

2:27_PM Case Experience From Germany Virtual Satellite Presenter: Felix Mahfoud

2:37_PM Preparing For Implementation Of RDN: Where Do We Go From Here?

Virtual Satellite Presenter: Naomi Fisher 2:47_PM Panel Discussion

Virtual Discussants: Chandan Devireddy, Naomi Fisher, Felix MahfoudSatellite Presenters: Ajay J. Kirtane

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Satellite: Pulmonary Artery Denervation for Pulmonary Hypertension

Satellites _




3:00 PM - 4:00 PM

Pulmonary Artery Denervation for Pulmonary Hypertension

3:00_PM Opening Speech Satellite Presenter: Gregg W. Stone

3:03_PM Pulmonary Artery Hypertension Classification and Autonomic Nervous System Involvement

Virtual Satellite Presenter: Soban Umar 3:13_PM Panel Discussion 3:18_PM Outcomes of Pulmonary Artery Denervation for Treatment of PAH

Satellite Presenter: Gregg W. Stone 3:30_PM Panel Discussion 3:38_PM Long-term Mortality after PADN in Patients with PAH

Virtual Satellite Presenter: Shao-Liang Chen 3:46_PM Panel Discussion 3:51_PM A “Curable” PAH Patient by PADN

Virtual Satellite Presenter: Hang Zhang 3:58_PM Closing Remarks

Satellite Presenter: Gregg W. Stone _

Satellite: Intrepid TMVR Early Experiences

Satellites _






4:00 PM - 5:00 PM

Intrepid TMVR Early Experiences

4:00_PM Intrepid TA Data Review and Program Update Satellite Presenter: Martin B. Leon

4:15_PM Expanding Treatable Anatomies with TMVR Satellite Presenter: Scott Lim

4:30_PM Intrepid TMVR-TF Experience Virtual Satellite Presenter: Firas Zahr

4:45_PM Discussion Discussant: Martin B. Leon, Scott Lim

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Satellite: Leading with evidence, choosing with confidence -TARGET Release, It Works

Satellites _




6:00 PM - 7:00 PM

Leading with evidence, choosing with confidence -TARGET Release, It Works

6:00_PM Opening & Welcome Satellite Presenter: Martin B. Leon

6:03_PM TARGET AC 4-year Results & Deep Dive in Diabetes Subgroup Virtual Satellite Presenter: Alexandra J. Lansky

6:13_PM Discussion Moderators: Martin B. LeonVirtual Discussants: Andreas Baumbach,

Yaling Han, Alexandra J. Lansky, Bo Xu 6:21_PM TARGET CTO 1-year Results

Virtual Satellite Presenter: Yaling Han 6:31_PM Discussion

Moderators: Martin B. LeonVirtual Discussants: Andreas Baumbach, Yaling Han, Bo Xu

6:39_PM TARGET Clinical Trials Roadmap & TARGET IV NA Trial Design

Satellite Presenter: Martin B. Leon 6:49_PM Discussion

Moderators: Martin B. LeonVirtual Discussants: Andreas Baumbach, Yaling Han, Bo Xu

6:57_PM Closing Satellite Presenter: Martin B. Leon

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Aortic Stenosis, Aortic Insufficiency, and TAVR III

Structural: Valve _

Moderated Posters



8:00 AM - 9:12 AM

Aortic Stenosis, Aortic Insufficiency, and TAVR III Moderators: Ariel Finkelstein Discussants: Stanley J. Chetcuti, Omar K. Khalique, Duane S. Pinto

8:00_AM TCT 53: Same Day Discharge Post-Transcatheter Aortic Valve Replacement Using a Standardized Clinical Pathway During the COVID-19 Pandemic: The PROTECT TAVR Study

Moderated Poster Presenter: Madeleine Barker 8:07_AM Discussion 8:12_AM TCT 54: Trends in Utilization and Outcomes Associated With Use of

Transcatheter Aortic Valve Replacement According to Frailty Moderated Poster Presenter: Aaqib H. Malik

8:19_AM Discussion 8:24_AM TCT 55: Lifetime Management of Patients With Symptomatic Severe

Aortic Stenosis: A Computed Tomography Simulation of Serial Transcatheter Aortic Valve Replacements

Moderated Poster Presenter: Giorgio A. Medranda 8:31_AM Discussion 8:36_AM TCT 56: Long-Term Clinical Outcome and Performance of Balloon-

Expandable versus Self-Expanding Transcatheter Aortic Valve Replacement



Moderated Poster Presenter: Andrea Scotti 8:43_AM Discussion 8:48_AM TCT 57: Updated Clinical and Procedural Outcomes in TAVR for

Bicuspid versus Tricuspid Aortic Valve Stenosis Moderated Poster Presenter: Mohammad Mehdi Ansari

8:55_AM Discussion 9:00_AM TCT 44: The Impact of Transcatheter Aortic Valve Replacement on

Gastrointestinal Bleeding in Aortic Stenosis Moderated Poster Presenter: Catalin Toma


Imaging and Physiology II

Coronary: CHIP Coronary: Core _

Moderated Posters



9:15 AM - 9:51 AM

Imaging and Physiology II Moderator: Hector M. Garcia-Garcia

9:15_AM TCT 84: Serial NIRS-IVUS Assessment of Changes in Coronary Lumen Area During 2-Year Follow-up: Insights From the PROSPECT ABSORB Trial

Moderated Poster Presenter: Mitsuaki Matsumura 9:22_AM Discussion 9:27_AM TCT 85: Mechanisms of In-Stent Restenosis in the Ostial Right

Coronary Artery Moderated Poster Presenter: Kei Yamamoto

9:34_AM Discussion 9:39_AM TCT 86: Anatomic and Functional Discordance Among Patients With

Non-Obstructive Coronary Disease Moderated Poster Presenter: Jennifer Rymer


Structural Heart Disease and Intervention

Coronary: CHIP Structural: Non-Valve _

Moderated Posters



11:00 AM - 12:00 PM

Structural Heart Disease and Intervention Moderators: Ioanna Kosmidou Discussants: Maurice Buchbinder, Ruby Satpathy

11:00_AM TCT 129: Use of the PRECISE 3D-CT Morphological Classification for Percutaneous Closure Treatment Selection in Patients With Ventricular Septal Rupture.

Moderated Poster Presenter: Eduardo A. Arias 11:07_AM Discussion 11:12_AM TCT 130: Initial Results From the VECTOR-HF Trial- A System for

Remote Left Atrial Pressure Monitoring for Patients With Heart Failure

Moderated Poster Presenter: Leor Perl 11:19_AM Discussion 11:24_AM TCT 131: Incidence and Time Course of Atrial Fibrillation Following

PFO Closure in Patients With Implantable Loop Recorder Device Moderated Poster Presenter: Johanna Ben-Ami

11:31_AM Discussion 11:36_AM TCT 132: Short and Long Term Performance of Alcohol Septal

Ablation in Patients With Hypertrophic Obstructive Cardiomyopathy Moderated Poster Presenter: Ahmad Mahmoud

11:43_AM Discussion 11:48_AM TCT 133: New Onset Atrial Fibrillation After Patent Foramen Ovale

Closure in Patients Over the Age of 60 Moderated Poster Presenter: Hoang Nguyen


LAA Closure


Moderated Posters





12:00 PM - 12:24 PM

LAA Closure Moderators: Maurice Buchbinder, Carlos E. Sanchez Discussants: Brijeshwar Maini, Ramon Quesada, Ruby Satpathy

12:00_PM TCT 95: TEE- and Fluoroscopy-guided WATCHMAN Implantation Without Administration of Iodinated Contrast

Moderated Poster Presenter: Torsten P. Vahl 12:07_PM Discussion 12:12_PM TCT 96: Trends and Readmissions Rates After Left Atrial Appendage

Occlusion According to Frailty Moderated Poster Presenter: Aaqib H. Malik


PCI and PCI Outcomes II

Coronary: CHIP Coronary: Core _

Moderated Posters



1:00 PM - 1:24 PM

PCI and PCI Outcomes II Moderators: Donald Cutlip, Stephen G. Ellis Discussants: IN-HO CHAE, Gennaro Giustino, Alfredo E. Rodriguez

1:00_PM TCT 116: Impact of Optimal Medical Therapy on 10-Year Mortality After Coronary Revascularization

Moderated Poster Presenter: Patrick W. Serruys 1:07_PM Discussion 1:12_PM TCT 118: Propensity-Adjusted Population-Based Analysis of Impella in

Patients Undergoing High-Risk PCI From a Large-Scale Claims Dataset Moderated Poster Presenter: Alexandra J. Lansky


Pulmonary Vascular Diseases

Endovascular Structural: Non-Valve _




8:00 AM - 9:00 AM

Pulmonary Vascular Diseases Moderators: M Chadi Alraies, Wissam A. Jaber Discussants: Vikas Aggarwal, Subhash Banerjee, James S. Eadie

8:00_AM TCT 594: Arterial Circle Of Vieussens And Pulmonary Artery Fistula: A Rare Clinical Association

Moderated Challenging Case Presenter: Anand Reddy Maligireddy 8:07_AM Discussion 8:12_AM TCT 595: Transcatheter Correction of Superior Sinus Venosus Atrial

Septal Defect (SVASD) With Partial Anamolous Pulmonary Venous Connection (PAPVC) Using Aortic Stent Graft



Moderated Challenging Case Presenter: Radha Priya Yalamanchi 8:19_AM Discussion 8:24_AM TCT 596: Transcatheter Pulmonic Valve Implantation of a Sapien Ultra

Valve Within a Palmaz Stent in a Patient Presenting With Severe Pulmonic Homograft Stenosis

Moderated Challenging Case Presenter: Imran BAIG 8:31_AM Discussion 8:36_AM TCT 597: Endovascular Treatment of Massive Interatrial Thrombus

Moderated Challenging Case Presenter: Santhosh Jay Mathews 8:43_AM Discussion 8:48_AM TCT 598: Pulmonary Vein Stenosis Secondary to Fibrosing

Mediastinitis With Hemodynamic Assessment Before and After Stenting

Moderated Challenging Case Presenter: Brenden Ingraham 8:55_AM Discussion

_

PCI Complications

Coronary: CHIP _




9:15 AM - 9:39 AM

PCI Complications Moderators: Steven R. Bailey, Rafael Beyar Discussants: David L. Fischman, Jacqueline E. Tamis-Holland

9:15_AM TCT 586: Cause If You Perfed It You Could Have Put A Ring On It: The First In Human Use Of The Ringer Perfusion Balloon Catheter For The Management Of Coronary Perforation

Moderated Challenging Case Presenter: Christopher Li 9:22_AM Discussion 9:27_AM TCT 587: Coronary Angioplasty Turned Catastrophic: Never-

Ending Complications

Moderated Challenging Case Presenter: Siddhartha Mengi 9:34_AM Discussion

_

Plaque Modification and Lithotripsy

Coronary: CHIP Endovascular _




11:00 AM - 11:48 AM

Plaque Modification and Lithotripsy Moderators: Lorenzo Azzalini, Hayder Hashim Discussants: Perwaiz M. Meraj, Ravish Sachar

11:00_AM TCT 589: Unexpected Complication of Shockwave Lithoplasty in a Previously Stented Coronary Artery

Moderated Challenging Case Presenter: Eric Chang 11:07_AM Discussion 11:12_AM TCT 590: ‘Rota Tripsy’ of Tortuous Calcified LAD/D1 Bifurcation

Moderated Challenging Case Presenter: Ali Farooq 11:19_AM Discussion 11:24_AM TCT 591: Intravascular Lithotripsy to the Rescue. Underexpanded

Stent With Recurrent STEMIs Moderated Challenging Case Presenter: Adnan Kassier

11:31_AM Discussion 11:36_AM TCT 592: Percutaneous Axillary Access For Endovascular Iliac Artery

Revascularization, Including CO2 Angiography, IVUS Based Re-Entry and Lithoplasty, In The Setting Of Bilateral Hostile Groins

Moderated Challenging Case Presenter: Hady Lichaa 11:43_AM Discussion

_

ACS, NSTEMI, and STEMI





9:15 AM - 9:39 AM

PCI Complications Moderators: Steven R. Bailey, Rafael Beyar Discussants: David L. Fischman, Jacqueline E. Tamis-Holland

9:15_AM TCT 586: Cause If You Perfed It You Could Have Put A Ring On It: The First In Human Use Of The Ringer Perfusion Balloon Catheter For The Management Of Coronary Perforation


Ending Complications Moderated Challenging Case Presenter: Siddhartha Mengi







11:00 AM - 11:48 AM

Plaque Modification and Lithotripsy Moderators: Lorenzo Azzalini, Hayder Hashim Discussants: Perwaiz M. Meraj, Ravish Sachar



Moderated Challenging Case Presenter: Ali Farooq 11:19_AM Discussion

11:24_AM TCT 591: Intravascular Lithotripsy to the Rescue. Underexpanded Stent With Recurrent STEMIs

Moderated Challenging Case Presenter: Adnan Kassier 11:31_AM Discussion 11:36_AM TCT 592: Percutaneous Axillary Access For Endovascular Iliac Artery



_






12:45 PM - 1:45 PM

ACS, NSTEMI, and STEMI Moderators: Francesco Franchi, Diego D. Grinfeld Discussants: Vikas Aggarwal, Marc D. Feldman, Zachary George

12:45_PM TCT 515: Erdheim-Chester Disease Presenting as a STEMI Moderated Challenging Case Presenter: Abdullah Pervaiz

12:52_PM Discussion 12:57_PM TCT 516: A Challenging Case Of STEMI With Cardiogenic Shock Due

To Early Failure Of Vein Graft Bypass Post Biological Bentall Intervention On A 54 Year-Old Woman: Successful PCI Guided By CTA

Moderated Challenging Case Presenter: Michel Doucet 1:04_PM Discussion 1:09_PM TCT 517: Anterior STEMI With Cardiogenic Shock Post-cardiac Arrest

and CPR: Remarkable LV Recovery With Coronary SuperSaturated Oxygen Delivery Combined With Impella and PCI



9:15 AM - 9:51 AM

PCI Complications Moderators: Steven R. Bailey, Rafael Beyar Discussants: David L. Fischman, Marie-Claude Morice, Jacqueline E. Tamis-Holland

9:15_AM TCT 584: Case Series Reporting Perforations A Cathlab Nightmare How to Get Out of This Critical Complication

Moderated Challenging Case Presenter: Rohit Mody 9:22_AM Discussion 9:27_AM TCT 586: Cause If You Perfed It You Could Have Put A Ring On It: The

First In Human Use Of The Ringer Perfusion Balloon Catheter For The Management Of Coronary Perforation


Ending Complications Moderated Challenging Case Presenter: Siddhartha Mengi




Moderated Challenging Case



11:00 AM - 11:48 AM

Plaque Modification and Lithotripsy Moderators: Lorenzo Azzalini, Hayder Hashim Discussants: Subhash Banerjee, Perwaiz M. Meraj, Ravish Sachar



Moderated Challenging Case Presenter: Ali Farooq 11:19_AM Discussion 11:24_AM TCT 591: Intravascular Lithotripsy to the Rescue. Underexpanded

Stent With Recurrent STEMIs Moderated Challenging Case Presenter: Adnan Kassier

11:31_AM Discussion 11:36_AM TCT 592: Percutaneous Axillary Access For Endovascular Iliac Artery



_



Moderated Challenging Case



12:45 PM - 1:45 PM

ACS, NSTEMI, and STEMI Moderators: Francesco Franchi, Diego D. Grinfeld Discussants: Vikas Aggarwal, Marc D. Feldman, Zachary George

12:45_PM TCT 515: Erdheim-Chester Disease Presenting as a STEMI Moderated Challenging Case Presenter: Abdullah Pervaiz

12:52_PM Discussion 12:57_PM TCT 516: A Challenging Case Of STEMI With Cardiogenic Shock Due

To Early Failure Of Vein Graft Bypass Post Biological Bentall Intervention On A 54 Year-Old Woman: Successful PCI Guided By CTA

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Last Updated 11/04/2021 Page: 2