Las Vegas, NV4-Dec-10

Emarit Ranu MSEE MSBS, Ewan Gillespie MBA, Kerry Bradley MS Boston Scientific Neuromodulation

Valencia, CAUSA

The Benefits of Tight Contact Spacing: Computational Model on Avoiding Stimulation Gaps

Modeling: E. Ranu.

Modeling based on: Rattay, F, “Analysis of models for extracellular fiber stimulation,” IEEE Trans Biomed Eng., Jul;36(7):676-82, 1989.

2/522

22

2

2 2

4 zx

zxI

x

Vf elee

(mV/cm2)

• Maps the change in potential on the nerve.

• A function of position relative to electrode.

• Shows the level depolarization and hyperpolarization.

• Any depolarization above threshold causes neurons to fire.

Activating Function: Contact Distance

Modeling: E. Ranu.

Modeling based on: Rattay, F, “Analysis of models for extracellular fiber stimulation,” IEEE Trans Biomed Eng., Jul;36(7):676-82, 1989.

2/522

22

2

2 2

4 zx

zxI

x

Vf elee

(mV/cm2)

• Maps the change in potential on the nerve.

• A function of position relative to electrode.

• Shows the level depolarization and hyperpolarization.

• Any depolarization above threshold causes neurons to fire.

Activating Function: Contact Distance

Modeling: E. Ranu.

Modeling based on: Rattay, F, “Analysis of models for extracellular fiber stimulation,” IEEE Trans Biomed Eng., Jul;36(7):676-82, 1989.

2/522

22

2

2 2

4 zx

zxI

x

Vf elee

(mV/cm2)

• Maps the change in potential on the nerve.

• A function of position relative to electrode.

• Shows the level depolarization and hyperpolarization.

• Any depolarization above threshold causes neurons to fire.

Activating Function: Contact Distance

Modeling: E. Ranu.

Modeling based on: Rattay, F, “Analysis of models for extracellular fiber stimulation,” IEEE Trans Biomed Eng., Jul;36(7):676-82, 1989.

2/522

22

2

2 2

4 zx

zxI

x

Vf elee

(mV/cm2)

• Maps the change in potential on the nerve.

• A function of position relative to electrode.

• Shows the level depolarization and hyperpolarization.

• Any depolarization above threshold causes neurons to fire.

Activating Function: Contact Distance

Modeling: E. Ranu.

Modeling based on: Rattay, F, “Analysis of models for extracellular fiber stimulation,” IEEE Trans Biomed Eng., Jul;36(7):676-82, 1989.

2/522

22

2

2 2

4 zx

zxI

x

Vf elee

(mV/cm2)

• Maps the change in potential on the nerve.

• A function of position relative to electrode.

• Shows the level depolarization and hyperpolarization.

• Any depolarization above threshold causes neurons to fire.

Activating Function: Contact Distance

Tight Contact Spacing: Rolling Cathodes

Modeling based on: Rattay, F, “Analysis of models for extracellular fiber stimulation,” IEEE Trans Biomed Eng., Jul;36(7):676-82, 1989.

Modeling: E. Ranu.

Wide Contact Spacing: Rolling Cathodes

Modeling based on: Rattay, F, “Analysis of models for extracellular fiber stimulation,” IEEE Trans Biomed Eng., Jul;36(7):676-82, 1989.

Modeling: E. Ranu.

The Benefits of Tight Contact Spacing

Modeling based on: Rattay, F, “Analysis of models for extracellular fiber stimulation,” IEEE Trans Biomed Eng., Jul;36(7):676-82, 1989.

TightContinuous

WideDiscontinuities

Modeling: E. Ranu.