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[ ANNUAL REPORT 2003 ] Kyphon’s vision: Improve patient quality of life through revolutionizing the practice of medicine.

Kyphon Annual Report 03

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Improving patient's lives through Innovation, evolution and ultimate revolution of this spinal compression fracture repair technology.

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Page 1: Kyphon Annual Report 03

[ A N N U A L R E P O R T 2 0 0 3 ]

Kyphon’s vision: Improvepatient quality of lifethrough revolutionizingthe practice of medicine.

Page 2: Kyphon Annual Report 03

Kyphon is driven by our mission:To be the recognized global leader in restoring spinal function through minimally invasive therapies.

>>

Page 3: Kyphon Annual Report 03

[ T O O U R S H A R E H O L D E R S , C U S T O M E R S A N D E M P L O Y E E S ]

I am pleased to report the progress of Kyphon during 2003. This was asignificant and important year in thedevelopment, growth and financialperformance of our Company. Duringthe year, we successfully broadenedfocus from our initial market opportunity in enabling the treatmentof osteoporosis-related vertebral fractures and have now built a broaderfoundation to become a leading innovator in minimally invasive spinal fracture therapies.

Our strategic expansion was supportedby strong financial and operationalachievements throughout 2003. Forthe year, net sales increased 74% to$131 million and we leveraged thisgrowth into pro forma net income of$8.7 million, or $0.21 per share. Afteryears of significant investment in ourbusiness, fiscal 2003 was our firstprofitable year. Our organization isvery proud of this achievement. >>

Richard W. MottPresident and Chief Executive Officer

Page 4: Kyphon Annual Report 03

INNOVATION

> > Ron Luperine , retired banker Age: 62

Diagnosis:

Location: Castro Valley, Calif. USA

Steroid-induced fracture

A lung ailment slowed Mr. Luperine down for four years, causing doctors toprescribe a corticosteroid. Unfortunately, the drugs caused him to lose bonemass—a common side-effect of steroid regimens—and he developed osteoporosis. His resulting spinal fracture was so debilitating that a painpump was implanted to manage the pain. Following a Balloon Kyphoplastyprocedure to treat his fracture, the pump was removed, and Mr. Luperine isnow happy to “be living and getting around again.”

I NNOVAT ION CREATES OPPOR TUN ITY Kyphon was founded upon a truly

innovative technology. Our kyphoplasty and fracture reduction products enable spine

specialists to provide therapies to a significant patient community that they did not

treat previously. This community represents our core market of patients with spinal

fractures caused by osteoporosis.

This technological advance—balloon-based, minimally invasive spinal fracture

treatment—creates a significant market opportunity for Kyphon. We believe that

550,000 patients are diagnosed with 700,000 vertebral compression fractures due to

osteoporosis each year in the United States and Europe. During 2003, we believe that

our products were used in over 33,000 procedures, which represents only six percent

of our $2.2 billion core market opportunity.

With innovation as our guiding principle, we are developing additional therapies to

provide spine specialists with alternatives for patients with a variety of spinal fractures.

In the near term, we are concentrating on developing minimally invasive procedural

solutions for spinal fractures caused by cancer and trauma.

With the addition of these incremental market opportunities, we will address the

three most common causes of spinal fractures and a potential market of over 900,000

fractures, valued at $3 billion, annually.

Page 5: Kyphon Annual Report 03

2001 2002 2003

36

76

131

Revenue (in millions)

Recent advances in surgical imaging technology are enabling minimallyinvasive, image-guided surgery in the spine.

Page 6: Kyphon Annual Report 03

1

2

EVOLUTION

20022001 2003

New Products

Far left: KyphX® Latitude™ Curette enablesuniform scraping and scoring of bone in the spine.Left: KyphX® Bone Biopsy Device cutscleanly through cancellous bone for easyspecimen collection.

2003 WAS A YEAR OF GROWTH AND EVOLUT ION FOR KYPHON

This past year included a series of important milestones in Kyphon’s evolution

as a leading medical device company.

During the year, we established a strong foundation for continued growth by

focusing on enhancing our organizational infrastructure. Specifically, we

expanded our senior leadership team, grew our employee base to over 440

individuals, and implemented the Six Sigma methodology for identifying areas

of operational improvement and employing successful solutions.

To support this growth, we recently moved into new corporate headquarters in

Sunnyvale, California, more than doubling our facility space. This new facility

will allow for significant growth in our technology research, development

and manufacturing capacity, while supporting the implementation of our

marketing and sales strategies.

BU I LD ING A POWERFUL CHANNEL TO THE MARKET Our direct

sales organization plays a vital role in working with the 3,900 spine specialists

we had trained worldwide by the end of this past year. We expanded our

surgical sales organization during 2003 as we continued to support significant

interest from the spine specialist community. As a complement to this effort, we

deployed a second, independently managed Spine Education Specialist (SES)

sales organization in 2003. This group is focused on educating the broader

medical community about treatment options for patients with spinal fractures.

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Page 7: Kyphon Annual Report 03

> > Christine Siegel, teacher Age: 57

Diagnosis:

Location: Greenbrae, Calif. USA

Myeloma-induced fractures

Fighting a blood cancer like multiple myeloma is frightening enough;add the consequences of related spinal fractures and life can be moredifficult. Ms. Siegel lost 6 inches of height from five fractures in herback due to myeloma and was “bed ridden for over a year while taking (strong opoids) for pain.” After a Balloon Kyphoplasty procedure to repair four spinal fractures, she threw away all of thepain killers. “The cancer caused me to fall apart, this procedure putme back together again.”

KyphX® Exact™ Inflatable Bone Tamp with rigid stainless steel shaft allows for fine-tuning of unidirectional balloon inflation for focused fracture reduction.

KyphX® Elevate™ Inflatable Bone Tamp with advanced balloon design results in preferential inferior/superior inflation profile.

Page 8: Kyphon Annual Report 03

REVOLUTION

> > Jan Van Mol

creative agency owner Age: 36

Diagnosis:

Location: Louvain, Belgium

While vacationing in France, Mr.Van Mol was flying his hang gliderwhen something went terribly wrong.The sail collapsed, causing him toslam his back into a high tree and suffer a spinal fracture and a brokenarm. After a painful nine-hourcar ride back to Belgium, he wastreated with a Balloon Kyphoplastyprocedure using a biomaterial. “Iimmediately started walking. In twoweeks, I was able to ride on mymotorcycle again.”

Traumatic fracture

Page 9: Kyphon Annual Report 03

2001 2002 2003

Spine Specialists Trained Worldwide

3900

2700

1500

I believe that we are unique in the medical device industry in employing two

separate but complementary sales organizations that work with the surgical and

primary care physician communities.

FOCUS ON NEW PRODUCT DEVELOPMENT Our powerful channel to

the market enables Kyphon to monitor the evolving dynamics and needs of the

spine community so we can provide our customers with new products that will

enhance their practices. Specifically, we launched 12 new products during

2003, which is a significant achievement for our organization.

Looking ahead to 2004 and beyond, I am very excited about our April 1, 2004

510(k) clearance by the U.S. Food & Drug Administration (FDA) of our

proprietary KyphX® HV-R™ PMMA Bone Cement for use in kyphoplasty. We

now will be able to provide and promote a complete procedural solution for

spine specialists who treat patients with these spinal fractures. Perhaps more

importantly, we believe clearance to promote the cleared clinical outcomes of

kyphoplasty to the referring physician community and among patients and

caregivers will continue to enhance our ability to penetrate our core market

over the long term.

This clearance is a seminal milestone in the history of our Company and has

clearly established Kyphon as a world class innovator in minimally invasive

spinal fracture therapies.

A REVOLUT ION IN M IN IMALLY INVAS IVE SP INE SURGERY

We believe that kyphoplasty is the first example of what will become a signifi-

cant trend in spine surgery: minimally invasive, restorative therapies that

enable spine specialists to provide patients with significant clinical outcomes

and short hospital stays. The strategic goal of Kyphon is to be the recognized

leader in this ongoing movement and we are actively investigating next

generation technologies.

Page 10: Kyphon Annual Report 03

2001 2002 2003 20022001 2003

Global Sales Force Countries Served

85

130

215

10

1719

ESTABL I SH ING A GLOBAL FRANCH ISE With the success we have had generating operating leverage

in our core business in the U.S. and primary countries in Europe, this is the right time for Kyphon to invest

in geographic expansion. International sales contributed 10 percent of our corporate revenue in 2003, which

reflects the significant but nascent opportunity for kyphoplasty outside of the U.S. During the year, we set

the stage for expanding our operations further into Europe as well as into Canada, and parts of Central and

South America. In addition, we completed an important planning process preparing for our entrance into

Japan, the world’s third largest medical device market. Progress in all of these geographies is important to our

business, and we will continue to invest in establishing kyphoplasty with our products as a treatment

alternative throughout the world.

PREPARED FOR CONT INUED SUCCESS As I contemplate all of the advances we made in 2003, and

the momentum we carry into 2004, I couldn’t be more excited. I believe that the foundation we have estab-

lished is a testament to the talent and dedication of the Kyphon employees throughout the world. The entire

Kyphon team appreciates and thanks all of our shareholders for their continued support and the recognition

of our growing family of customers.

Sincerely,

Richard W. MottPresident and Chief Executive Officer

Sales Today

Near Term Expansion

Key Longer Term Goals

Page 11: Kyphon Annual Report 03

MANAGEMENT TEAM

Richard W. MottPresident, Chief Executive Officer and Director

Karen D. Talmadge, Ph.D.Executive Vice President, Chief ScienceOfficer, Co-Founder and Director

Jeffrey L. KaiserVice President, Finance andAdministration and Chief FinancialOfficer

Cindy M. DomecusVice President, Clinical Research and Regulatory Affairs

Avram A. Edidin, Ph.D.Vice President, Research andDevelopment

Mary K. HaileyVice President, Reimbursement

Stephen C. HamsVice President, Human Resources

Anthony J. RecuperoVice President, Sales

Elizabeth A. RothwellVice President, Quality and Operations

David M. ShawVice President, Legal Affairs andGeneral Counsel

Julie D. TracyVice President, Marketing

Bert VanderveldeVice President and General Manager,Kyphon Europe

BOARD OF D IRECTORS

James T. TreaceChairman of the Board of DirectorsJ & A Group, LLC

Stephen M. CampeInvestor Growth Capital, Inc.

Douglas W. KohrsAmerican Medical Systems, Inc.

Jack W. LasersohnThe Vertical Group

Elizabeth H. WeathermanWarburg Pincus, LLC

Richard W. MottPresident and Chief Executive Officer,Kyphon Inc.

Karen D. Talmadge, Ph.D.Executive Vice President, Chief ScienceOfficer, and Co-Founder, Kyphon Inc.

ANNUAL MEET ING

Kyphon’s annual meeting will be held at 2:00 p.m., June 16, 2004 at Kyphon’s corporate offices,1221 Crossman AvenueSunnyvale, California 94089

ADDIT IONAL INFORMATION

Corporate CounselWilson Sonsini Goodrich & RosatiPalo Alto, California

Public Accounting FirmPricewaterhouseCoopersSan Jose, California

Stock Transfer AgentU.S. Stock Transfer Corporation1745 Gardena AvenueGlendale, California 91204Phone: 800.835.8778

> > Ellen Simpson, M.D., retired pediatric cardiologist Age: 86 (left)

Chris Kern , former x-ray technician Age: 84 (right)

Andy, canine companion (far right)

Diagnosis:

Locations: San Francisco and Fairfax, Calif. USA

Dr. Simpson (four fractures from osteoporosis repaired in August 2003) and Ms. Kern(two fractures repaired in January 2003) met at a holiday party and found out that theyhad much in common—retired healthcare professionals who love gardening and livingactive lives in Northern California. They are also two of the hundreds of thousands ofpeople who suffer spinal fractures due to osteoporosis each year in the United States. Whatbrought these two women together for this photograph is a procedure called BalloonKyphoplasty. They underwent the procedure to treat the pain, deformity and diminishedquality of life they were suffering due to their fractures. Both are excited now about living pain free lives and getting back to their respective gardens.

Osteoporotic fractures

Page 12: Kyphon Annual Report 03

Corporate Offices: Kyphon Inc. 1221 Crossman Avenue Sunnyvale, California 94089 USA Phone: 408.548.6500

www.kyphon . com

© 2004 Kyphon Inc. All rights reserved.