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Circular ver. Mar 20, 2019

KHUPO 19th ANNUAL INTERNATIONAL

PROTEOMICS CONFERENCE

‘Proteomics for Precision Medicine’

March 28 (Thu) – 29 (Fri), 2019

5F, Global Education Center for Engineers,

Seoul National University, Seoul, Korea

The Korean Human Proteome Organization

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WELCOME MESSAGE

Dear colleagues,

We are delighted to announce that KHUPO's 19th Annual International Proteomics

Conference is scheduled to be held March 28–29, 2019 at Global Education Center for

Engineers located in Seoul National University. On behalf of the Organizing Committee,

I cordially welcome you to this wonderful event.

The theme of this year’s conference is “Proteomics for Precision Medicine”. Four plenary

lectures and ten symposia are planned. The symposia will cover various subjects

including two clinical proteomics sessions. We have also reserved one session for

presentations by scientists in their early career to encourage the participation of the

young talents in the field. As KHUPO is entering its 19th year and chosen to host

AOHUPO 2020, our annual conference will continue to provide an excellent platform

for sharing the ideas and building friendship among the participants.

I look forward to greeting you all in Seoul at the 19th Annual International Proteomics

Conference.

Best Wishes,

Je-Yoel Cho, DVM, PhD

President, The Korean Human Proteome Organization

Professor, Department of Biochemistry, College of Veterinary Medicine

Seoul National University

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ORGANIZING COMMITTEE

President Je-Yoel Cho, Seoul National University

Board of Trustee

Ho Jeong Kwon, Yonsei University

Chan-Wha Kim, Korea University

Byoung Chul Park, Korea Research Institute of Bioscience and

Biotechnology

Young Mok Park, Korea Basic Science Institute

Young-Ki Paik, Yonsei University

Jong Shin Yoo, Korea Basic Science Institute

Bonghee Lee, Gachon University

Kyung Soo Hahm, BioLeaders Corp.

Vice Presidents

Young-Soo Kim, Seoul National University

Cheolju Lee, Korea Institute of Science and Technology

Hyo Hyun Baek, Shimadzu Scientific Korea Corp.

Jin Han, Inje University

Hun Choi, Scinco Co., LTD

Secretary General J. Eugene Lee, Korea Research Institute of Standards and Science

Secretary of Academic Affair Eugene C. Yi, Seoul National University

Jin Young Kim, Korea Basic Science Institute

Member of Academic Affair

Min-Sik Kim, Daegu Gyeongbuk Institute of Science and Technology

Young Hye Kim, Korea Basic Science Institute

Jun-Seok Lee, Korea Institute of Science and Technology

Secretary of Planning Kwang Pyo Kim, Kyung Hee University

Hyun Joo An, Chungnam National University

Secretary of Financial Affair Hookeun Lee, Gachon University

Kang-Sik Park, Kyung Hee University

Secretary of Editorial Affair Jeehyeon Bae, Chung-Ang University

Jae Ho Kim, Pusan National University

Member of Editorial Affair Jong Hyuk Yoon, Korea Brain Research Institute

Secretary of Education Zee-Yong Park, Gwangju Institute of Science and Technology

Ji Eun Lee, Korea Institute of Science and Technology

Secretary of International Cooperation Tae-Hoon Lee, Chonnam National University

Kyunghee Byun, Gachon University

Secretary of Membership

Sayeon Cho, Chung-Ang University

Moon-Chang Baek, Kyungpook National University School of

Medicine

Secretary of Advertising Hye-Jung Kim, KBIO New Drug Development Center

Byong Chul Yoo, National Cancer Center

Secretary of Public Relation

Moon Ju Cho, Bruker Korea Co., LTD

Marcelino Bae, Waters Korea Limited

Kyoung Jun Ahn, Scinco Co., LTD.

Eunyoung Lim, Thermo Fisher Scientific Korea

Yong-Seung Shin, Agilent Technologies

Byung-Hee Shin, AB SCIEX Korea

Chair, Committee for Election Affair Sung Goo Park, Korea Research Institute of Bioscience and

Biotechnology

Chair, Committee for Fund-Raising

Affair

Byoung Chul Park, Korea Research Institute of Bioscience and

Biotechnology

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GENERAL INFORMATION

Title 19th Annual International Proteomics Conference

Theme Proteomics for Precision Medicine

Date March 28 (Thu) – 29 (Fri), 2019

Venue 5F, Global Education Center for Engineers, Seoul National University

Program 4 Plenary Lectures, 10 Symposia, Poster Session, Reception etc.

Industrial Events Exhibition, Exhibition Tour, etc.

Expected

Participants 300 Participants (over 8 countries)

Organized by The Korean Human Proteome Organization

Official Language English

Website http://2019.khupo.org

PLENARY SPEAKERS

Stephen Pennington

(University College

Dublin)

David James

(University of

Sydney)

Harald Mischak

(Mosaiques

Diagnostics)

Jong Shin Yoo

(Korea Basic Science

Institute)

SYMPOSIA

Protein Modification Young Scientists

Proteins in Pathology Exploring the Unknown Proteins

Biomarkers for Disease Antibody & Biologics

Omics Research in Aging Multi-omics

Clinical Proteomics Proteogenomics

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PROGRAM AT A GLANCE

16:00

Break 20 min Break 20 min

12:00

Exhibition Tour&Poster(12:40-14:00) Exhibition Tour&Poster(12:40-14:00)

13:00

Break 20 min

SYM-4(15:30-16:40)

"Omics Research in

Aging"

SYM-5(15:30-16:40)

"Clinical

Proteomics"

SYM-9(15:30-16:40)

"Multi-omics"

SYM-10(15:30-16:40)

"Proteogenomics"

14:00

SYM-2(14:00-15:10)

"Proteins in

Pathology"

SYM-3(14:00-15:10)

"Biomarkers for

Diseases"

SYM-7(14:00-15:10)

"Exploring the

Unknown

Proteins"

17:00

PL-2(17:00-17:40) by David James PL-4(17:00-17:40) by Jong Shin Yoo

General Assembly(17:40-)

Awards&Closing(17:40-)

18:00

Reception(18:30-)

SYM-1(9:40-10:50)

"Protein Modification"

Registration

Opening Ceremony(9:30-9:40)

March 28 (Thu) March 29 (Fri)

8:00

9:00

SYM-8(14:00-15:10)

"Antibody &

Biologics"

15:00

Break 20 min

Lunch(11:50-12:40)

10:00

11:00Break 20 min

PL-1(11:10-11:50)

by Stephen Pennington

Lunch(11:50-12:40)

Break 20 min

PL-3(11:10-11:50)

by Harald Mischak

SYM-6(10:00-10:50)

"Young Scientists"

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SCIENTIFIC PROGRAM

March 28 (Thu), 2019

8:30- Registration

9:30-9:40 Opening Ceremony

SYM-1 Protein Modification (Chair: Hyun Joo An, Chungnam National University)

Room 520

9:40-10:03 Brain somatic mutations in neurological disorders

Jeong Ho Lee (KAIST)

10:03-10:26

Monitoring of Non-human Glycan Motif in Biotherapeutics for Immunogenicity

Prediction

Unyong Kim (GLYCAN Co., Ltd.)

10:26-10:49

Defining the molecular mechanism of the UBA6-USE1 in lung cancer

Peter Chang Whan Lee (University of Ulsan College of Medicine, ASAN Medical

Center)

10:50-11:10 Break

PL-1 (Chair: Je-Yoel Cho, Seoul National University)

Room 520

11:10-11:50

Development and Delivery Advanced Protein Biomarker Tests for an Era of

Precision Medicine

Stephen Pennington (University College Dublin)

11:50-12:40 Lunch

Exhibition Tour & Poster

12:40-14:00

SYM-2 Proteins in Pathology

(Chair: Youngsoo Kim, Seoul

National University College of

Medicine, Han Suk Ryu, Seoul

National University Hospital)

Room 520

SYM-3 Biomarkers for Diseases

(Chair: Sang Hoon Song, Seoul

National University Hospital)

Room 517

14:00-14:17

Prediction of response to PD-1

blockade by immune cell profiling.

(Machine learning analysis of

multiplex IHC images)

Discovery and validation of cancer

biomarkers by DIA and targeted

proteomics

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Woo Ho Kim (Seoul National

University College of Medicine)

Sumio Ohtsuki (Kumamoto

University)

14:17-14:34

Tyrosine aminoacyl-tRNA synthetase

sensitize breast cancer to the

combined chemotherapeutic regimen

Han Suk Ryu (Seoul National

University Hospital)

Exosomes are Tiny vesicle but Huge

impact on cancer biomarker study

Jisook Park (Samsung Medical Center,

Sungkyunkwan University School of

Medicine)

14:34-14:51

Improved Quantitation of HER2

protein by Multiple Reaction

Monitoring Mass Spectrometry in

Formalin-Fixed Paraffin-Embedded

(FFPE) Breast Cancer Tissue

Youngsoo Kim (Seoul National

University College of Medicine)

Discovery of blood biomarker for

major mental illness by high-

throughput plasma proteome profiling

Dohyun Han (Seoul National

University Hospital)

14:51-15:08

In-depth Serum Proteomics Reveals

Biomarkers of Psoriasis Severity and

Response to Traditional Chinese

Medicine

Xiaobo Yu (Beijing Proteome

Research Center)

Serum Trace Elements and Their

Associations with Breast Cancer

Subgroups in Korean Breast Cancer

Patients

Rihwa Choi (Green Cross

Laboratories)

15:10-15:30 Break

SYM-4 Omics Research in Aging

(Chair: Je Kyung Seong, Seoul

National University)

Room 520

SYM-5 Clinical Proteomics

(Chair: Hyewon Chung, Konkuk

University School of Medicine,

Konkuk University Medical Center)

Room 517

15:30-15:47

Developmental proteomics: the

importance of age specific differences

in the human plasma proteome

Vera Ignjatovic (Murdoch Children’s

Research Institute)

Clinical Proteomic Study and

Diagnostic Application for Antibiotic

Resistant Bacteria Using High-End to

Low-End Mass Spectrometry

Je-Hyun Baek (Seegene Medical

Foundation)

15:47-16:04

Effect of aging on lipidomic changes in

mouse serum, kidney, and heart by

nanoflow UHPLC-ESI-MS/MS

Clinical proetomics, divergence and

convergence of mass spectrometry

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Myeong Hee Moon (Yonsei University) Kyunggon Kim (Asan Medical

Center/University of Ulsan)

16:04-16:21

The role of Dlk1-Dio3 miRNA cluster in

muscle aging

Kwang-Pyo Lee (Korea Research

Institute of Bioscience &

Biotechnology)

Quantitative proteomic analysis of

aqueous humor from patients

with age-related macular degeneration

Hyewon Chung (Konkuk University

School of Medicine, Konkuk University

Medical Center)

16:21-16:38

Proteomic analysis of an Alzheimer's-

in-a-dish model

Young Hye Kim (Korea Basic Science

Institute)

In-depth proteomic analysis of pleural

effusion for lung cancer biomarker

discovery

Chia-Jung Yu (Chang Gung University)

16:40-17:00 Break

PL-2 (Chair: Je Kyung Seong, Seoul National University)

Room 520

17:00-17:40

Global redox proteome and phosphoproteome analysis reveals novel mode of

Akt regulation

David James (University of Sydney)

17:40- General Assembly

Room 520

18:30- Reception

1F BBQ cafe

March 29 (Fri), 2019

SYM-6 Young Scientists (Chair: Jun Won Choi, Korea Institute of Science and

Technology)

Room 520

10:00-10:10

Proteomics approach to discover the unrinary protein biomarkers to predict

kidney function decline in type 2 diabetes

Hee-Sung Ahn (Asan Medical Center)

10:10-10:20

Raft-localized CD147 with proximal proteins confers drug-resistance

phenotype in cancer stemness

Sohyun Kim (Seoul National University)

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10:20-10:30

iNrich, a rapid and robust method to enrich N-terminal proteome in a highly

multiplexable platform

Shinyeong Ju (Korea Institute of Science and Technology)

10:30-10:40 Novel protein markers for both human and canine breast tumors in plasma

Hyoung-Min Park (Seoul National University)

10:40-10:50

N-Glycoprotein Biomarkers for Detection of Hepatocellular Carcinoma by

Parallel Reaction Monitoring

Kwang Hoe Kim (Korea Basic Science Institute)

10:50-11:10 Break

PL-3 (Chair: Youngsoo Kim, Seoul National University College of Medicine)

Room 520

11:10-11:50

Application of proteomics in clinical diagnosis and patient management: from

discovery to actual routine implementation

Harald Mischak (Mosaiques Diagnostics)

11:50-12:40 Lunch

Exhibition Tour & Poster

12:40-14:00

SYM-7 Exploring the Unknown

Proteins

(Chair: Ho Jeong Kwon, Yonsei

University)

Room 520

SYM-8 Antibody & Biologics

(Chair: Junho Chung, Seoul National

University College of Medicine)

Room 517

14:00-14:23

Exploring the Function of Dark

Proteome for Biomedical

Applications

Young-Ki Paik (Yonsei University)

14:00-

14:17

Fully international system of

units-traceable protein

quantification: what we can

really measure

Ji-Seon Jeong (Korea Research

Institute of Standards and

Science)

14:23-14:46

Identification of Missing Proteins

in Human Olfactory Epithelial

Tissue by Liquid

14:17-

14:34

Development of a Novel

Internalizing Human Antibody

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Chromatography-Tandem Mass

Spectrometry

Heeyoun Hwang (Korea Basic

Science Institute)

Targeting TSPAN8-Expressing

Epithelial Ovarian Cancer

Sukmook Lee (Kookmin

University)

14:46-15:09

What we can learn from

biomarker study; priori

probability, patient-derived cancer

model, and proteogenomics

Tadashi Kondo (National Cancer

Center)

14:34-

14:51

Current status and challenges

of 'antibody-drug

conjugate(ADC)' for anti-

cancer therapy

Dae Hee Kim (Scripps Korea

Antibody Institute)

14:51-

15:08

Antibodyome analysis using

proteome microarrays

Chien-Sheng Chen (National

Cheng Kung University)

15:10-15:30 Break

SYM-9 Multi-omics

(Chair: Eugene C. Yi, Seoul

National University)

Room 520

SYM-10 Proteogenomics

(Chair: Sang Myung Woo, National

Cancer Center)

Room 517

15:30-15:47

Multi-omics of the myocardium

during ischemia / reperfusion

injury

Stuart Cordwell (The University

of Sydney)

Proteomics analysis of mitotic

chromosomes with using nano Random

Forest

Shinya Ohta (Kochi University)

15:47-16:04

Metabolic signatures of steroids

in clinical endocrinology

Man Ho Choi (Korea Institute of

Science and Technology)

Proteogenomic data sharing of

National Cancer Center Korea

Dongwan Hong (National Cancer

Center)

16:04-16:21 Multi-Omics analysis of pancreatic

ductal adenocarcinomas

Proteogenomics: the path to precision

medicine in cholangiocarcinoma

Sang Myung Woo (National Cancer

Center)

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Min-Sik Kim (Daegu Gyeongbuk

Institute of Science and

Technology)

16:21-16:38

Multiomics-Engaging colors

Sureyya Ozcan (Middle East

Technical University)

Proteogenomic Analysis of a Model

Diatom

Feng Ge (University of Chinese

Academy of Sciences)

16:40-17:00 Break

PL-4 (Chair: Jin Young Kim, Korea Basic Science Institute)

Room 520

17:00-17:40 Glycoproteomics and Clinical Applications by Mass Spectrometry

Jong Shin Yoo (Korea Basic Science Institute)

17:40- Awards & Closing

Room 520

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POSTER SESSION

All poster presentations must be in English. Presenters are responsible for setting up

their displays, being present during the entire scheduled poster session, and removing

their displays at the conclusion of the poster session. On your assigned day, please

plan to spend the entire session at your poster for questions and discussion. Each

poster should be allocated on a poster board corresponding to its abstract number.

※ Posters are displayed for entire day, although presenters are only required to be

present at their board from 12:40 to 14:00 on March 29 (Fri).

※ Poste Size 90cm wide x 120cm high (Board Size 95cm wide x 165cm high)

※ Poster Set-up March 28 (Thu) 8:00-11:00, Poster Session March 29 (Fri) 12:40-14:00,

Poster Removal March 29 (Fri) after 18:00

Category

Protein Modification

Proteins in Pathology

Biomarkers for Diseases

Omics Research in Aging

Clinical Proteomics

Young Scientists

Exploring the Unknown Proteins

Antibody & Biologics

Multi-omics

Proteogenomics

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Exhibition Information

Date & Time: March 28 (Thu) – 29 (Fri) 9:00-18:00

Place: 5F Lobby, Global Education Center for Engineers, Seoul National

University

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Booth No.

No. Exhibitor No. Exhibitor

1 SMAnalytical 11 Shimadzu Scientific Korea Corp.

2 Younginfrontier 12 Agilent Technologies

3 Kim & Friends Inc., 13 CHEMBRIDGE

4

Waters Korea Limited

14 Korea Basic Science Institute

5 15 Korea Centers for Disease Control

and Prevention

6 AB SCIEX Korea Pte. Ltd. 16 PhileKorea Technology, Inc

7 Bio-Medical Science Co., Ltd. 17 SARTORIUS KOREA BIOTECH Co, Ltd

8 SeouLin Bioscience 18 Bruker Korea, SCINCO

9 ANYGEN CO., LTD. 19

10 Binaree, Inc.

Exhibition Tour

Time Exhibitor Time Exhibitor

12:40-12:45 SMAnalytical 13:15-13:20 Binaree, Inc.

12:45-12:50 Younginfrontier 13:20-13:25 Shimadzu Scientific Korea

Corp.

12:50-12:55 Waters Korea Limited 13:25-13:30 Korea Centers for Disease

Control and Prevention

12:55-13:00 AB SCIEX Korea Pte. Ltd. 13:30-13:35 PhileKorea Technology, Inc

13:00-13:05 Bio-Medical Science Co., Ltd. 13:35-13:40 SARTORIUS KOREA BIOTECH

Co, Ltd

13:05-13:10 SeouLin Bioscience 13:40-13:45 Bruker Korea, SCINCO

13:10-13:15 ANYGEN CO., LTD.

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VENUE

5F, Global Education Center for Engineers (GECE, building no. 38), Seoul National

University

Address: 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, Korea

Homepage: http://convention.gece.snu.ac.kr/convxe/index.php

Floor Plan

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TRANSPORTATION

From Incheon Airport to GECE

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From Gimpo Airport to GECE

18

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Awards

Qualification: Poster presenters

The number of people: 10 people

Award details: Cash prize and Certificate

Winner announcement: March 29 (Fri) 17:40 Awards & Closing Ceremony

Sponsored by

Welcome Reception

Date & Time: March 28 (Thu) 18:30

Venue: 1F BBQ cafe, Global Education Center for Engineers, Seoul National

University

Sponsored by