Dr. Lipkowitz, Professor, has been named Chairman of the Departmenteffective August 1, 2003. He replaces Dr. John Hershberger who served asChairman. Dr. Hershberger will continue as Associate Chairman.

Dr. Lipkowitz earned his bachelor’s degree at SUNY, Geneseo in 1971, anda Ph.D. from Montana State University in 1975. He served as a postdoctoralfellow in 1976 at the Ohio State University and was Visiting Research Facultyin 1980 at Princeton University.

He joins us from Indiana University-Purdue University at Indianapolis. Hisresearch interests are in Computational Chemistry. His current work focuseson studies of enantioselective binding in chiral chromatography; studies ofmolecular structure with empirical force fields and molecular orbital theory;studies in chirality.

Kenny Lipkowitz joins Department

Department of Chemistry

North Dakota State UniversityBiochemistry - IACC Building

Volume 1 Number 1

Dr. Kenny Lipkowitz

Fall 2003

& Molecular Biology

Chemistry - Ladd Hall

The chairman of the ChemistryDepartment has asked the universityto merge the Department ofBiochemistry and Molecular Biologywith the Chemistry Department andto rename the organization as theDepartment of Chemistry andMolecular Biology. The name of thenew department is unique amongstchemistry departments nationwideand it reflects our interest in makingconnections with scientists in otherdisciplines who also work at themolecular level.

The size domain in which chemiststhink and work is typically on theangstrom to nanometer scale. Hence,much of our view of the scientificlandscape is usually a molecularview. Nowadays there exist manypeople from disciplines as disparateas biology and geology in thesciences to technologists, engineersand manufacturers standing at the

threshold of the nano-doorway, eagerto enter this realm of smallness wecall “home.” As scientists who arewell versed in the art and science of“nano,” we chemists welcome thoseresearchers to our small and importantworld; it is more than a matter ofcollegiality to help those newcomersstep into the molecular world bysharing what we know with them…it is a significant investment in ourfuture to seek and nurture suchassociations. The interface withmolecular biology is thus timely,prudent and necessary.

The Biochemistry and MolecularBiology Department currently hassix faculty members including: D. KSrivastava, Derek Killilea, RobertSparks and Steven Meinhardt, whoremain active in teaching and researchalong with James Fleeker and ArlandOleson who are retired. We are nowsearching for a new assistant

professor to replace Professor Fleekerand soon thereafter we shall seek areplacement for Professor Oleson.Those new faculty members couldbe traditional biochemists, molecularbiologists, medicinal chemists orsomething else. They could beexperimentalists, informaticists ortheorists; given the encompassingnature of the new department we havethe latitude to develop in a way thattraditional chemistry departmentscan’t and we are excited about theprospects for our future. An emphasison agriculturally related molecularscience will be maintained but growthinto new areas related to health willsoon take place. The Department ofChemistry and Molecular Biology willexpand onto the third floor of the IACCbuilding. We will soon be working onan integrated curriculum at thegraduate and undergraduate levels andwe will have a new website for the newdepartment by 1, January 2004.

Creation of a New Department

The Department of Chemistry & Molecular Biology 2 Fall 2003

An Introduction From the Chairman

At 7:15 pm, on Monday evening,September 26th of last year after mygraduate course on applied bondingtheory had concluded, I looked outfrom my office window at the mutedglow of the day’s sunset reflectingfrom the buildings of downtownIndianapolis; the sight of sandstone-reflected orange, red and almost-purple was warm and alluring, and itwas one that I had grown accustomedto seeing for nearly 3 decades. Iasked myself if this was the view Iwanted to see for the next twodecades of my life, and, as attachedto that city as I had become over theyears, the surprising answer was no…it was time to move on.

I became Chair of Chemistry at NDSUthis summer and I now live far fromthe city lights on a small farm nearHorace. Looking out upon the prairiefields, I find them too alluring in astark, flat way, and I know there willbe many contemplative early-eveningmoments for me to enjoy here; I amalready happy.

I am a Computational Chemist.Computational Chemistry is amultidisciplinary endeavor thattranscends traditional barriersseparating Mathematics, Physics,Chemistry and Biology. This disciplineis de facto a consequence of thecomputer and I have had theopportunity to ride the wave ofinnovation and to help mould this fieldof science and determine where it isgoing. That notwithstanding, mybackground is in synthetic chemistry;I was granted tenure in the PurdueUniversity School of Science basedon my syntheses using pericyclicreactions. I became more interestedin understanding and predicting theoutcome of those reactions than in theproducts themselves, and I found thatquantum theories could be applied tothis class of reactions to help explainand predict their outcomes. I lived adouble life in synthesis and theoryand I published that way. On the onehand I attended hard-core syntheticchemistry meetings with organic andmedicinal chemists and on the otherhand I attended theory meetings with

physicists and physical chemists. Ipublished under two names: KennethLipkowitz, the synthetic chemist andKenny Lipkowitz, the theorist.

In the early days we relied uponclunky, slow, mainframe computersthat were shared with other research-ers, students and administrators,

complete isolation from one another,leaving both groups oblivious to thebenefits each could bring to the other’sdiscipline.

I started by developing workshops,symposia and national meetings onthe topic of computational chemistry.I was elected as a faculty member atthe Summer Workshops in AppliedQuantum Mechanics sponsored bythe Quantum Chemistry ProgramExchange (QCPE). I used thisopportunity to guide the workshopattendees more towards syntheticchemistry and towards using a non-quantum mechanical method calledmolecular mechanics, which is nowa mainstay of modern molecularsimulation and molecular design in thepolymer, agrochemical and pharma-ceutical industries. I also co-organizedthe first international conference onMolecular Mechanics in Indianapolisin 1983 with my colleague from EliLilly and Company, Don Boyd. Basedon the success of that conferencewe wrote a proposal to the GordonResearch Conferences to developa new research conference oncomputational chemistry. Our proposalwas accepted and Don and I were thefirst co-chairmen of the GordonResearch Conference on Computa-tional Chemistry. I also began givinglectures on the topic of molecularmechanics at national AmericanChemical Society meetings andstarted warning bench chemists tonot treat the software as a “black box.”It was clear that the bench chemistswanted to use theory in their work butthere were so many pitfalls to avoidthat it became almost impossible totrain them properly via semi-annualmeetings alone. Worse yet was therealization that the theory bookswere almost impenetrable to benchchemists.

To rectify that I put forth a series oflaboratory experiments for undergradu-ates to help them learn aboutcomputational chemistry in theirformative years of training. I wantedto fully integrate bench work withcomputing. That effort was followed

Dr. Kenny Lipkowitz

Cont’d page 3

but within a few years computermanufacturers were able to makemachinery that was affordable fordepartments and even for individualresearch groups. The availability ofaffordable computers was enoughimpetus for me to completely switchfrom synthesis to theory. That financialreason wasn’t why I switched,however. My real reason for focusingon computational chemistry wasinstead based on the observation thatneither group understood what theother group was doing. And theycertainly didn’t talk to one anotherabout either science or teaching.My goal, then, was twofold: to bridgethe gap between these two groups(theorists and bench chemists) andto push forward the discipline ofcomputational chemistry.

I made a concerted effort to bridgethis gap in both research and teaching.The need to develop pedagogyinvolving computational chemistrywent hand-in-hand with my researchbecause at that time there were nobooks, classes or meetings that wouldallow for cross-fertifilization to takeplace. Instead, separate theory andsynthesis conferences were held, in

The Department of Chemistry & Molecular Biology 3 Fall 2003

An Introduction From the Chairmancont’d

by the introduction of a book seriescalled Reviews in ComputationalChemistry. This book series differsfrom a typical research oriented reviewseries in that it is pedagogicallydriven. As editor of the series we askour invited authors to begin fromground zero and provide a low-leveltutorial for the non-specialist on thetopic being reviewed. If I could do itall over again I would call the seriesTutorials in Computational Chemistrybecause it has the reputation of atutorial series anyway. Reviews inComputational Chemistry is now onthe ISI list of the top10 most-citedserials and there is a reason for that;we first educate the bench chemistand then we provide critical reviews ofthe field so that they can better carryout their research. The divide betweenbench chemists and theorists hasshrunk; experimentalists are doingtheory and there are more and moretheoreticians becoming involved insynthesis and medicinal chemistry,especially under the umbrella of“informatics.” This trend is likely tocontinue into the near future.

My research has always beenmultidisciplinary and at that veryexotic but thin boundary betweentheory and application. The emphasisof my work is on chirality, especiallyin the areas of chiral separations inchromatography and more recentlydesigning chiral catalysts forasymmetric induction. One of thestrengths of this department is insynthetic chemistry (organic,polymers, inorganic) and that wasone of the compelling reasons forme to come here.

Now that you know something aboutme, I invite you to stop in when youget back to Fargo and to introduceyourself. If that’s not possible, I lookforward to seeing you at the next ACSmeeting. At the very least, we willkeep you apprised of all the newdevelopments that will soon takeplace in Chemistry as it merges withthe Department of Biochemistry andMolecular Biology. Until then I wishyou good health and continuedsuccess with your work.

PromotedJohn Hershbergerhas been promotedto Professor bythe State Board ofHigher Educationat its May meetingand approved byPresident JosephChapman.

Dr. Hershberger earned his bachelor’sdegree at the University of California,Santa Barbara in 1982, and a Ph.Dfrom Yale University in 1986. He joinedthe NDSU in 1989.

His research interests are chemicalreaction kinetics and dynamics, withemphasis on the study of elementaryradical-radical and radical-moleculereactions of interest primarily incombustion chemistry. He is alsointerested in atmospheric chemistryand chemical vapor depositionprocess. More information about hisresearch can be found on the web.

http://www.chem.ndsu.nodak.edu/faculty/hershberger.html

He is also an excellent pianist.

John Hershberger

Professor D.K. Srivastava

WelcomeProfessor S. Derek KillileaProfessor D. K. SrivastavaDr. Steven MeinhardtDr. Robert SparksAnn Huseby

(From the former Biochemistry Department)

New FacultyUwe Burghaus joins NDSU and comesfrom Ruhr-Universitaet Bochum inGermany where he has been aResearcher/Lecturer.

He received hisPh.D. in 1995 fromthe Free Universityin Berlin. In jointprojects with theFritz-Haber Inst.(Max PlanckSociety), he studiedlow temperature

Emilio XavierEsposito is thenew Staff Compu-tational Chemist.He earned hisPh.D. fromDuquesne Univer-

Uwe Burghaus

scholar at USC) he switched hisinterest to metal oxide catalysts,specializing in methanol synthesis.In 2002 he finished his habilitation inPhys. Chem. on that topic. Togetherwith his students he will be focusingon metal oxide catalysts studied withthe molecular beam scattering tech-nique and with an electron spectro-scopic method - HREELS.

CO oxidation,which is important for cleaningexhaust pollution by a three-waycatalyst. After postdoctoral fellow-ships (UCSB, Genoa, brief visiting

Emilio Esposito sity in the springof 2003.

Emilio’s research interests are QSAR,comparative (homology) modelling,and simulated docking.

He is excited to be at NDSU and tohave the opportunity to work with newpeople and new research projects. Inhis spare time Emilio enjoys skating,hiking and rock climbing.

The Department of Chemistry & Molecular Biology 4 Fall 2003

2002 Individual Gifts

Steven BahrDr. James E. BilligmeierDr. Donald W. BoerthMichael BourdeauN. Bradford BrakkeDr. Jan F. BranthaverDr. Charles E. BuckDr. David L. CarlsonM. V. CarneriYenson E. ChinDr. Armin L. ClobesMr. & Mrs. Austin CummingsDowney C. Cunningham, Jr.Dr. Daryl J. DoyleParker EricksonEarl EvenstadDr. James L. FaschingAlvin E. Fasching, Jr.Julian H. FossenRonald L. FredericksonMr. & Mrs. Robert FrieseJohn L. GaleJulie A.H. GeorgeDr. John T. GilmoreDixie GrossmanElnore A. GrowVernon L. GuyerDr. Byung H. HanDr. & Mrs. Richard HansenBrian C. HeathMr. & Mrs. Clarence HildebrandDr. & Mrs. Loren HillDr. Darold D. HoltenClarence E. HottmanDr. Fu C. HuangDr. Earl C. HutchinsDr. & Mrs. Morris JohnsonDr. Craig A. KapferElwood S. KendrickDr. Michael KlinkhammerDr. Steve KloosDr. Jerome M. KnoblichDr. Dennis R. KnudsenFrancis KochDonald F. Koenecke

Dr. P. R. LakshmananPark W. LawrenceArthur N. LeadbetterDr. & Mrs. James LofgrenDr. Maxwell LucciRobert J. LudwigsenDelon D. MaasDr. Glen E. MartinDr. Gregory J. McCarthyLinda B. McHarnessAllan R. MeathRoxane F. MeidingerDr. & Mrs. Marvin MillerDr. Bradford J. MuellerDr. David W. NaegeliCurtis H. NelsonTimothy O. NelsonRobert A. NewmanDr. Robert E. OlsonGrant & Gabrielle OlsonStephen S. OlsonScott L. PetersonMrs. Christa R. RajendraDr. Reuben D. RiekeLynette I. RiggioDr. David J. RisloveRay M. RobinsonArt SchafferDr. & Mrs. Joseph SchmitMary Beth SchwehrDean & Tammy SlettenMr. & Mrs. W. Blair SmallwoodSusan M. SnyderDr. & Mrs. James SugiharaEdwin W. SwitzerLara K. TebeliusDavid ThraneDr. & Mrs. Robert TuckerMrs. Judy TuominenFrederick B. TurnerIrvin L. WangsnessRoger C. WedelDr. Duane E. WeisshaarWillard G. WittemanRoy WongDr. Wayne Worner

Scholarships Awarded FromThese Gifts were:

DONALD BOLIN MEMORIAL SCHOLARSHIP:Awarded to outstanding student majorsin Chemistry:

Christine Bultema, Fargo, NDLindell Kemmet, Tappan, NDKarla Radke, Fargo, NDAmy Richter, Rugby, ND

CHEMISTRY DEPARTENT HONOR SCHOLARSHIP:Scholarship presented to chemistry majorson the basis of scholastic achievement.

Krista Berge, Fargo, NDEvan Erickson, Lakeville, MN

RALPH DUNBAR MEMORIAL SCHOLARSHIP:Scholarships awarded to chemistry majorson the basis of scholastic achievement andcharacter as exemplified by Ralph E. Dunbar,Dean of the College of Chemistry andPhysics, 1945-1960.

Courtney Boucher, Worthington, MNHeidi Doctor, Jamestown, NDEvan Erickson, Lakeville, MNDerik Hoerner, Richardton, NDAaron Krueger, MInot, NDSpicer Lattu, Littlefork, MNShawn Power, Langdon, NDJerry Tveidt, Pierre, SD

ROY MILDE FELLOWSHIP AWARD:A scholarship presented to an outstandinggraduate student who has been enrolled in thechemistry program for more than one year.Preference is given to graduates of highschools and colleges in ND and the uppermidwest.

Jake Zimmerman, Wolf Point, MT

JAMES & MAY SUGIHARA SCHOLARSHIP:A scholarship presented to outstandingstudents majoring in chemistry.

Jessica Goreham, Fargo, NDSandra Hagen, Watertown, SDCurtis Kovash, Jr,, Mandan, ND

RICHARD GLENN WEDEL MEMORIAL SCHOLARSHIP:A scholarship presented to an outstandingstudent majoring in chemistry.

Daniel Keys, Carrington, ND

UNDERGRADIATE RESEARCH FELLOWSHIPS IN CHEMISTRY:These mentorships are awarded to freshmenmajoring in chemistry who demonstrate strongpotential for chemical research. The awardincludes a research position in a facultyresearch laboratory and a $1200 stipend.

David Schulz, Fargo, NDJonathan Pinke, Vergan, MNCurtiss Kovash, Jr., Mandan, NDSpicer Lattu, Littlefor, MN

See pictures page 5 Honors Day

The faculty, staff and students wish to thank the following alumni, friends, andfaculty for their generous gifts and pledges received from January 1, 2002through December 31, 2002:

2002 Corporate Matching Gifts

Altria Group Inc - Employee Involv ProgramBP Matching FundChevron Texaco CorporationDow Chemical CompanyExxon Mobil Foundation3M Company

Proctor & Gamble CompanyShell Oil Company FoundationMobil FoundationOsmonics, Inc.

The Department of Chemistry & Molecular Biology 5 Fall 2003

Honors Day

Graduation

Dr. & Mrs. Sugihara with Jessica Goreham.Karla Radkle and Associate Chairman, Dr. JohnHershberger.

Amy Richter Receives 2003Goldwater Scholarship

Amy Richter is one of two NDSU studentsselected for the prestigious Barry M.Goldwater Scholarships. Known as thepremier undergraduate award of its typein mathematics, natural sciences andengineering. The one and two-yearscholarships cover the cost of tuition,

On May 10, 2003 NDSU Chemistry grads joined the procession of graduates incommencement ceremonies held at the Fargodome. Below is a list of graduatecandidates as well as photos taken that day.

Bachelor’s Degrees:John GoeringSandra HagenRyan HeggeDaniel KeysMeghann KiddBradley KlindtLinda MizeurPanny NeisenGregory RohdeTheresa RosendahlScott Rothstein

Dr. John Hershberger and Gregory Rhode.

Daniel SattlerGalen SedoNathan Silvernail

Master’s Degrees:Jason Hallman

Ph.D Degrees:Jie HeGuoliang Chen

Dr. Dennis Tallman and Guoliang Chen.

Jie He.

housing, fees and books up to $7,500per year. Students are nominated by thefaculties of colleges and universitiesnationwide and selected through anindependent review process.

Richter, a chemistry major whosehometown is Rugby, ND., plans topursue a doctorate in chemistry, work inanalytical chemistry or polymer science

research and eventually teach. She is a2002-03 recipient of the Donald BolinMemorial Scholarship, the Albert C. BeanSr. Foundation Scholarship, George A.Nichols Scholarship and the ValsparFoundation Scholarship. In 2001-02, shereceived a chemistry department honorscholarship. Her advisor is DennisTallman, professor of Chemistry.

Award Winners

North Dakota EPSCoR has an-nounced the winners of the summer2003 Advanced UndergraduateResearch Awards (AURA) program.AURA provides undergraduatestudents up to $2,800 and theopportunity to participate in faculty-mentored research projects at NDSUand the University of North Dakota.Competing students submit applica-tions based on research topicssubmitted each fall by faculty fromthe sciences, engineering andmathematics. A faculty reviewcommittee ranks each student’sapplication, and awards are givendirectily to the winners. North Dakitaresidents and students enrolled atNorth Dakota University Systeminstitutions are eligible.

Chemistry students on the NDSUcampus award winners, their hometowns and mentors are:

Paul Barron, Ruthton, MN., Wenfang Sun.

Brandon Gustafson, West Fargo, NDGreg Cook.

Karla Radke, Fargo, ND Seth Rasmussen.

The AURA program has grown froma three-student pilot program in1987, to an average of 20 studentseach year between NDSU andUND. A total of 290 undergraduatestudents have received the awards.

ND EPSCoR is a federally and statefunded program designed to improvethe ability of university researchers tocompete more effectively for federal,regional and private research grantsin the sciences, engineering andmathematics.www.ndsu.nodak.edu/epscor

The Department of Chemistry & Molecular Biology 6 Fall 2003

News From Our Former Graduates

“I am currently working at the Univer-sity of Texas Medical Branch in a labwhere we are developing treatmentsagainst biological weapons attacks,and other products related to AIDSand cancer research.”

David E. VolkPhD Chemistry 1996

***

“I do receive the deparment newsletter.Keep them coming, I love them. I’mstill at Concordia College, Moorhead,MN and loving it. Have been full-timenow for the last 4 years. I took overthe Organic chemistry program fromDaryl Ostercamp (a legend here) afterhe completed his 42nd year of teach-ing and retired. Keep in touch.”

Drew RutherfordPhD Chemistry 1996

***

“I graduated from Dr. Boudjouk;s groupwith a M.S. in 1995. I currently workfor Cargill, Inc. as a New ProductDevelopment Manager. Ironically, Iwork for a former NDSU alumni whoalso graduated from Dr. Boudjouk’sgroup by the name of Kevin Andersonwho is Cargill’s Director of TechnologyDepartment. Kevin’s group in Cargilldevelops both products and technolo-gies for Cargill customers. Productsare typically chemically and physicallyengineered from the vast amount ofntural polymers Cargill, Inc. processesworld-wide daily. Some examples ofnatural polymer starting materials arecorn, soy beans, oats, sunflower,linseed, palm, etc. Kevin’s group alsodevelops technologies. Some of thelatest of Kevin’s inventions have beennew analytical techniques for measur-ing complex carbohydrate substrates.”

David GarlieM.S. Chemistry 1995

***

“A little information about me. I ammarried to wife Naomi and have twochildren, Nathan and Elayna. I went

back to NDSU in the fall of 1998 forElectrical Engineering and graduatedin August of 2000. I am employed as acommunications consultant/engineerby CC&I Engineering, Inc. located inPerham, MN.”

Michael KawlewskiB.S. Chemistry 1997B. S. Engineering & Architecture 2000

***

“It is very nice to hear from you. It isquite a long time after I left NDSU.After leaving NDSU in 1999, I didPost-Doc research at the Universityof Pittsburgh until September 2001.Since them I am working at PPGIndustries as a Sr. Research Chemist.”

Beon-Kyu KimPhD Chemistry 1999

***

“It looks like you found me! Currentlyat Harvard University, working towardsa Ph.D in organic chemistry (Mastersdegree was earned in June 2002).

The big news: I’m getting marriedAugust 16th here in Boston. Good tohear from you. Hope to see thenewsletter in my box soon.”

Scott PetersonBS 2000 former Dr.Cook undergrad

***

“I have been receiving the newsletter...they are great! I am finishing my 3rdyear of grad school at USM polymerscience dept., working on a PhD.”

Todd RoperBS 2000 ***

We have been trying to reach alumni via e-mail. Some of successful responses: ALUMNI:

ALUMNI: Please send us your e-mail address. We want to keep in touch.

r.overby@ndsu.nodak.edu

“The news is that I have retired after37 years at Montana State Universityin the Chemistry and BiochemistryDepartment. I have taken a newposition part time. The new position isDirector of the U-DOC Program thatserves high school students that wantto be doctors or dentists. It is specifi-cally for high school students thathave very high grades, have com-pleted their junior or senior year andcome from small communities,financially disadvantaged families,families where the parents have notattended college and minority families.They are here at MSU for six weekswhere they are given opportunities tosee what college is like and to map aplan to go to college and to preparefor application to medical or dentalschool. I also teach ‘my section’ of thefirst year medical school biochemistryand then we go off to Arizona for thewinters.”

Larry JacksonBiochemistry PhD 1966

***

“I graduated from NDSU in 1953 witha BS in Chemistry. Will be lookingforward to hearing the latest, espe-cially now that there are so manychanges being made.”

Esther BlaslBS 1953

***

“I am currently working on my PhD inPharmaceutical Sciences through theUniversity of Cincinnati. I am conduct-ing my research in Washington, DC inthe FDA’s Office of Cosmetics &Colors. My research is based on theevaluation of skin absorption, metabo-lism, and irritation promotion ofcosmetic ingredients.”

Angela EpplerBS 2000

***

Please keep us updated on address changes:r.overby@ndsu.nodak.edu

Also, if in town we will enjoy seeing you!

The Department of Chemistry & Molecular Biology 7 Fall 2003

compiled with field and industry datain writing petitions that are submittedto the EPA. Over the past 26 years theNDSU laboratory has analyzed over120 different projects covering cropsfrom dry beans to safflower to mint.

Three unique features of the IR-4Laboratory on the NDSU campusare that it obtains data to be used forpetitions to the EnvironmentalProtection Agency, it is the onlyGood Laboratory Practices (GLP)laboratory at NDSU and it is fullyfunded by USDA.

Currently the IR-4 Laboratory projectscover familiar crops such as turnips,beets, blueberries, peas, etc. Anunusual crop currently assigned tothe lab is mayhaw. Mayhaw is a berrycrop indigenous to the southern UnitedStates that is used for making jams,jellies, syrups and tastes like acrabapple. In a typical year, samplesfrom about 20 field sites from two tofour different projects are analyzed.IR-4 is one of the most productive

An analytical research lab on the thirdfloor of Loftsgard Hall quietly works onprotecting you and your food. It is partof a national cooperative effortbetween the United States Depart-ment of Agriculture (USDA), theCooperative State ResearchEducation and Extension Service(CSREES), and the AgriculturalResearch Service (ARS) to ensurethat the public is exposed to as littleas possible of the chemicals used tocontrol pests on foods while stillproviding growers with the tools theyneed to provide a safe and plentifulfood supply. This effort or project isknown as the Inter-Regional Project 4or IR-4, and it is now part of theDepartment of Chemistry andMolecular Biology.

IR-4 was established in 1963 by thedirectors of the State AgriculturalExperiment Stations of the land grantuniversities and the USDA to provideinformation to obtain regulatoryclearance for chemicals to be used onsmall acreage crops such as fruitsand vegetables. The agriculturalchemical industry lacks economicincentives to obtain registrations forthe use of these chemicals on minorcrops, and there was a need toprovide plant protection chemicals forfruits and vegetables. In 1977 theproject was widened to includeornamental crops such as nursery andflower crops, perennials, turf grasses,and forest seedlings.

The process begins at extensionfarms throughout the United Statesand Canada that grow the crops andapply the chemicals. These crops arethen shipped to one of four regionallaboratories at Cornell University(Geneva), Michigan State University,University of California Davis and theUniversity of Florida. There, theamount of chemical residue isdetermined.

The laboratory at NDSU is associatedwith the Michigan State laboratory,providing expanded capability forsample analysis.

Pesticide residue analysis began atNDSU in the Department of Agricul-tural Chemistry in 1964 by Drs. R.H.Smith and H.R. Klosterman incollaboration with Dr. D. Nelson,Department of Horticulture, and hascontinued to this day.

Inter-Regional Project 4 LabBy: Dr. Steven Meinhardt

Allen Peckrul, Roger Erber and Sheila Haugen.

Director: Dr. Steven Meinhardt.

The IR-4 laboratory was establishedat NDSU in 1974 in the Departmentof Biochemistry and was directed byDr. Doug Bristol.

In 1977, Dr. James Fleeker took overthe project and was the laboratorydirector until his retirement earlier thisyear.

In June 2003, Dr. Steven Meinhardtbecame the third director of thisfacility. The laboratory is staffed bytwo full time technicians, Allen Peckruland Roger Erber (both with more thanten years experience in analyticalchemistry) and one part timetechnician, Sheila Haugen. Thetechnicians develop analyticalmethods and process the samples.Most analysis is performed either byhigh performance liquid chromatogra-phy (HPLC) or gas chromatography(GC). There has been an increase inthe number of methods involvingmass spectrometry and it is hopedthat in the future the laboratory will beequipped with a GC mass spectrom-etry system. After sample analysis,analytical summary reports are writtenby the laboratory director and sent toIR-4 Headquarters. The information is

government programs, in part due tothe cooperation of the states and thehard work of the individuals in it. Theneed for this effort will continue intothe future and the satellite lab atNDSU will continue to ensure a safefood supply and support the needs oflocal and national growers.

The Department of Chemistry & Molecular Biology 8 Fall 2003

National ScienceFoundation Awards:

Professor Mukund Sibi -“Enantioselective Synthesis of B AminoAcids” awarded $511,000 for four years.

Dr. Greg Cook -“New Directions in Selectivity via Palladiumand Indium Mediated Methodology” awarded$313,000 for four years.

Under the Eisenhower/Title II Funds,ND secondary science teachers areparticipating in a summer seriesof graduate-level science courses,Chemistry II (Chemistry 432/632).

Date: June 9 - July 16Time: 1:15 - 3:05 pm M,T,W,ThLab: 3:15 - 4:25 pm M,T,W.Th

Dr. Denley Jacobson, ChemistryDepartment.

www.ndsu.edu/csme

Summer ProfessionalDevelopment Program for Science TeachersJune 9 - July 16

“R I S E”(Research Initiative ForScientific Enhancement) Grant“Improvement of ND TribalCollege Chemistry Instruction

Gary Stolzenberg and Denley Jacobson worked on the cooperative educationeffort with ND tribal colleges to improve preparation of healthcare professionalsservicing Native Americans.

A NIH grant, under their RISE (Research Initiative for Scientific Enhancementprogram) supported workshops at NDSU for Tribal College personnel onlaboratory techniques in organic and analytical chemistry, relating especiallyto water quality and constituents of plants. The funding is for 3 years; thisevolved from a preliminary workship at NDSU-Chemistry in 1999.

OtherActivities:

The Department of Chemistry& Molecular Biology

North Dakota State UniversityPO Box 5516

Fargo, ND 58105

Rose Overby, EditorDr. Kenny Lipkowitz, Chair

Dr. John Hershberger,Associate Chair

To obtain a copy or submit comments:e-mail:

R.Overby@ndsu.nodak.edu

New Graduate Students2003-2004Chad Amb Portland, NDPhilip Durham Indianapolis, INRyuji Hayashi Tokyo, JapanDon Klocke Carrington, NDJoel Lischefski Appleton, WISheikh Mustakim Dhaka, BangladeshScott Rothstein Sauk Rapid, MNJonathan Stack Indianapolis, INLi Wen Chengdu, China

Jake (from Lake Region) points out the dramaticdifference in detergent like properties by usingSudan III as a solubility indicator.

Charmaine Disrud works withstudents to follow the steps necessaryto making soap

Congratulations

Mukund Sibi

Greg Cook

The Department of Chemistry & Molecular Biology 9 Fall 2003

N o r t h D a k o t a S t a t e S c i e n ce & E n g i n e e r i n g F a i r

The Southeastern ND RegionalScience and Engineering Fair,sponsored by North Dakota StateUniversity and Society of AutomotiveEngineers was held at NDSU onMarch 18, 2003. The territory includedthe counties of Griggs, Steele,Barnes, Cass, Ransom, Richland andSargent.

Devany Schulz, SullivanMiddle School,, Fargo,ND,“Slick Solutions”.

The Winner.Amanda MauchHankinson, ND

Mara Paulson, SullivanMiddle School, Fargo, ND.

Visitors to the NMR Lab during Science & Eng. Fair days, April 3-4, 2003.

The annual state Science Olympiad competititon washeld on Saturday, April 26 at NDSU. The events werefor Division C schools (grades 9-12) and Division Bschools (grades 6-9).

Junior High from Des Lacs/Burlington,ND placed 2nd.

ND Governor’s SchoolJune 8 - July 19, 2003

The Governor’s School is free to students who havecompleted their sophomore or junior year in high school.It is held annually on the campus on North Dakota StateUniversity. If you are chosen to attend, you’ll live instudent residence halls on campus and eat meals in thestudent dining halls. You will be responsible for your owntransportation to and from home, as well as personalexpenses such as snacks and laundry.

http:govschl.ndsu.nodak.edu/gs98.html

The Department of Chemistry & Molecular Biology 10 Fall 2003

September 26-28,2003

Family Weekend is a chance forfamilies of current students to visitcampus and spend time with their sonor daughter while experiencing art,academics and athletics at NDSU.

More than 500 family memberstypically participate in the annualevent. Families can attend suchactivities as the president’s breakfast,pre-game barbecue and footballgame.

Family Weekend atNDSU

Research Experience for Undergraduates

Research in the PrairiesMay 25-Aug 2, 2003

North Dakota State UniversityChemistry & Pharmaceutical Sciences

Students involved in the 10 week program are paired with a participating faculty mentor and immersed in an independentresearch program. They will gain insight from the expertise of participating faculty members and will benefit from theopportunity to perform cutting-edge research using the facilities state-of-the art equipment. Participants are expected todedicate their time to the research program; therefore, students should not enroll for summer courses or take on employ-ment during the 10 week REU program. A stipend of $3,600 is awarded to each student.www.ndsu.nodak.edu/cobre/REU/REU.html

Wireless PersonalResponse SystemThis new technology helps facultykeep track of every person in a largeclass, including the student noddingoff in the back.

Additional events also are planned.For a detailed schedule, call Orientation andStudent Success at 701/231-8379.

Brian Nguyen, Laura Mergen, James Irwin, Darci Evans, Michael Low.Aaron Krueger not pictured.

REU 2003 Students:

Mentor:Brian Nguyen Dr. Stefan BalazNDSU Pharmacy

Laura Mergen Dr. Mahesh JasegaConcordia College

Michael Low Dr. Mukund SibiConcordia College

Aaron Krueger Dr. Sanku MallikNDSU

James Irwin Dr. Stefan BalazYoungstown State Pharmacy

Darci Evans Dr. Kenton RodgersJamestown College

The system—palm-sized transmitters,portable receivers and software—require every member of a class toanswer the instructor’s questions.Students use the transmitters toregister their answers.

The system tallies the students’responses, projecting a bar graph ona large screen. The display tellsstudents if they’re getting a concept,and teachers if they are conveying it.NDSU is a rarity for the number ofinstructors qualified to teach this way.

The Department of Chemistry & Molecular Biology 11 Fall 2003

ton

The Morgan Hill, Calif., firm’s plantwill develop and manufacture “smarttags,” which could revolutionizeretailing and supply-chain manage-ment. Known as “Radio FrequencyIdentification” tags, the chips areaffixed to products and informationis collected by radio transmission.The plant could be in operationas early as 2005, with about 300employees by 2006-07.

Alien Technologyselects NDSU

In Dunbar Hall: Center for Nanoscale Scienceand Enginnering process engineer BerndScholz works in the cleanroom on the NDSUcampus. Alien Technology Corp. plans onlocating a manufacturing plant in theuniversity’s Research and Technology Park.

L A B S

Materials Characterization Lab, Dunbar Hall.

Working with the Laser.

Hamilton LabChemistry Classes &Lab EnrollmentsChemistry 117 Lecture 54 studentsChemistry 117-2 Lecture 172 studentsChemistry 117 Labs 8 sectionsChemistry 121-1 Lecture 451 studentsChemistry 121-2 Lecture 454 studentsChemistry 122 Lecture 215 studentsChemistry 121 Labs 32 sectionsChemistry 122 Labs 5 sections

Evan Erickson, Darla Powell, Jason Rolfstad,Karen Beckman, David Schultz and Dr. DavidHamilton.

Chemistry DepartmentOffers Free Tutoring

Dr. Melvin Morris, Professor Emeritus, receivedthe College of Science and Math Award forDistringuished Service. He continues to offer“FreeTutoring” every day in the ChemistryDepartment and is very popular especially nearexam time.

American ChemicalSociety 225th ACSNational MeetingNew Orleans, Louisiana

Dr. Rasmussen, Dr. Hamilton with Chem Club atACS meeting.

Lipkowitz Lab moving in, Ladd Hall.

Ladd Hall, Chemisry Library:Heather Heger, Librarian.

New Biochemistry Teaching Lab, Dunbar Hall.

North Dakota State UniversityDepartment of Chemistry & Molecular BiologyP. O. Box 5516Fargo, ND 58105-5516

Non-Profit OrgU. S. Postage Paid

Permit No. 818Fargo, ND 58105

NMR LabBy Dan Wanner, NMR Manager

This composite photography, by NemSchlect, shows a panorama of theNMR lab. Not shown on the left are thecomputer workstations for the 300 and400 MHz NMR spectrometers. Thepicture is taken from just in front ofthe 400 MHz sample preparationbench which is also not shown. The400 MHz superconducting magnetstands out in the foreground, sup-ported by box-like anti-virbration legs.The oak platform to the left of the 400MHz magnet cryostat enables usersto insert their samples into the upperbarrel of the magnet. An upper barrelis in the bore of the magnet and isclearly noticeable in the center of the300 MHz cryostat, located directly

behind the large printer in the leftforeground. The two large stainlesssteel tubes, crossbar, and checkvalveassembly on top of the cryostats arecalled the helium manifold and serveto vent the evaporated helium gas andalso to transport liquid helium into thehelium cryostat below. The 500 MHzcryostat is in the right-center back-ground of the photograph, along theback wall and directly beneath thesmaller of the two overhead bays. The300 MHz and 400 MHz magnetcryostats are located beneath thelarge central bay, recessed to allowenough ceiling height for the liquidhelium transfer rods to be inserted intothe helium manifold. The helium levelsensor can be seen on top of the 400MHz spectrometer console which is tothe right and behind the 400 MHz

cryostat. The 500 MHz spectrometerconsole is concealed behind the 400MHz magnet and console; the 300MHz console is located behind theprinter in the foreground. Shelves,cabinets, and work benches are setalong three of the four walls. Thefourth wall, on the right side of thephotograph mounts air and nitrogengas supplies, filters, and two airconditioning units which keep theNMR lab between 66-68 Farenheitdegrees. The dashed safety line to theleft and left center of the photo marksthe position of the five Gauss fringe ofthe magnetic field. The fringe field isalso marked by two safety chains withwarning signs. The liquid nitrogentransfer dewar rests in the center ofthe photo. It is used for weekly liquidliquid nitrogen fills.